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Bleeding, Thrombosis and Vascular Biology

Editor-in-Chief: Giovanni de Gaetano, Italy | eISSN: 2785-5309

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  • PO106 | INTERACTIONS BETWEEN DIRECT ORAL ANTICOAGULANTS AND ANTIEPILEPTIC DRUGS (INTER-DOAC): A PROSPECTIVE OBSERVATIONAL STUDY A. Rafanelli1, C. Pizzanelli3, M. Biagini1, P. Chiarugi4, M. Casini4, P. Capozza5, G. Guarini5, L. Malloggi4, G. Siciliano3, R. De Caterina5|6, L. Carrozzi1|2, F. Pistelli1|2, L. Marconi2, A. Celi1|2, R. Pancani2 | 1Pulmonary Division, Dep. of Surgical, Medical and Molecular Pathology and Critical Care Medicine, University of Pisa, Pisa, Italy; 2Pulmonary Unit, Cardiothoracic and Vascular Dep., University Hospital of Pisa, Pisa, Italy; 3Neurology Unit, Dep. of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy; 4Clinical Chemistry Laboratory, Dep. of Laboratory Medicine, University Hospital of Pisa, Pisa, Italy; 5Cardiology Unit, Cardiothoracic and Vascular Dep., University Hospital of Pisa, Pisa, Italy; 6Cardiology Division, Dep. of Surgical, Medical and Molecular Pathology and Critical Care Medicine, University of Pisa, Pisa, Italy

    Annalisa Rafanelli
    26-10-2026
    https://doi.org/10.4081/btvb.2026.922
    48
    PDF: 25
  • PO041 | VARIABLE CLINICAL RESPONSE TO RECOMBINANT PORCINE FVIII IN ACQUIRED HAEMOPHILIA A: A TWO CASE EXPERIENCE WITH LABORATORY SUPPORTED MONITORING AM. Pizzini1, M. Bovara2, M. Sebastiani2, A. Fusco1, C. Fantoni1, M. Silingardi1, R. Mancini2, A. Coppola3 | 1Ambulatorio Emostasi & Trombosi, Dipartimento Medico - Ospedale Maggiore Bologna, Italy; 2Laboratorio Unico Metropolitano - Ospedale Maggiore Bologna, Italy; 3SDD Centro Hub Emofilia e MEC, Azienda Ospedaliero-Universitaria di Parma, Italy

    Attilia Maria Pizzini
    26-10-2026
    https://doi.org/10.4081/btvb.2026.857
    67
    PDF: 28
  • In this issue

    Giovanni de Gaetano, Chiara Cerletti
    10-07-2026
    https://doi.org/10.4081/btvb.2026.578
    1207
    PDF: 69
  • CO41 | Failure in assisted reproductive techniques: insights from the first registry E. Grandone1,3,4, C. Lodigiani2, D. Colaizzo3, M. Passaretti2, J. Khizroeva4, A. De Laurenzo3, P. Totaro5, E. Bucherini6, D. Baldini7, V. Bitsadze4, A. Makatsarya4, M. Mastroianno3, G. Piazza8, M. Othman9, M. Margaglione1 | 1University of Foggia, Italy; 2Humanitas University, Rozzano, Italy; 3IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy; 4First Sechenov University, Russia; 5Santa Maria Hospital, Bari, Italy; 6Angiologia, Faenza, Italy; 7Momo Fertilife, Bisceglie, Italy; 8Brigham Women Hospital, USA; 9Queen’s University, Kingston, Canada

    22-10-2025
    https://doi.org/10.4081/btvb.2025.310
    594
    PDF: 21
  • CO33 | Acquired hemophilia A in Liguria, Italy: what six years of data reveal C. Vernarecci1, A. C. Molinari1, P. Ballarino2, M. Caiti2, E. Cenni2, P. Moscatelli2, L. Banov1 | 1IRCCS Istituto Giannina Gaslini, Genova; 2IRCCS Policlinico San Martino, Genova, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.240
    628
    PDF: 41
  • PO142 | CROSS-TALK BETWEEN HEART AND BRAIN IN ATRIAL FIBRILLATION: ASSOCIATIONS BETWEEN CARDIAC REMODELING AND CEREBROVASCULAR LESION BURDEN IN THE STRAT-AF STUDY F. Alfano1|2, C. Barbato3, M. Berteotti1|2, L. Cosco1|2, A. Sammartino1|2, G. Guidotti1|2, V. Liberati1|2, G. Iula1|2, M. Papi1|2, A. Fidanzati1|2, B. Formelli3, E. Barucci3, G. Salti3, F. Fratini3, T. Lo Castro3, C. Parenti4, E. Fainardi2|5, A. Di Carlo4, E. Salvadori1, A. Poggesi1|3, R. Marcucci1|2 | 1Department of Experimental and Clinical Medicine, University of Florence, Firenze, Italy; 2Center for Atherothrombotic Diseases, Careggi University Hospital, Firenze, Italy; 3NEUROFARBA Department, Neuroscience Section, University of Florence, Firenze, Italy; 4Institute of Neuroscience, Italian National Research Council, Sesto Fiorentino, Italy; 5Neuroradiology Unit, Careggi University Hospital, Firenze, Italy

    Francesco Alfano
    26-10-2026
    https://doi.org/10.4081/btvb.2026.958
    59
    PDF: 29
  • PO078 | CARDIOVASCULAR EVENTS AND SUBCLINICAL ATHEROSCLEROSIS IN HEMOPHILIA A AND B PATIENTS: A MULTICENTER COHORT STUDY A. Napolitano, E. Zanon, L. Spiezia, G. Camporese, P. Scarinzi, F. Ahmad, G. Saggiorato, C. Bulato, S. Toffanin, S. Gavasso, P. Zerbinati, C. Simion, E. Campello, P. Simioni | Department of Medicine, University of Padova, Italy

    Angela Napolitano
    26-10-2026
    https://doi.org/10.4081/btvb.2026.894
    43
    PDF: 28
  • PO020 | EXTRACELLULAR VESICLE PROFILES REFLECT THROMBO-INFLAMMATORY ACTIVATION AND ARE ASSOCIATED WITH CLINICAL OUTCOMES IN LIVER CIRRHOSIS E. Campello1|3, S. Toffanin1|3, A. Zanetto2|3, F. Kymentie2|3, C. Bulato1|3, B. Serena1|3, C. Radu1|3, P. Burra2|3, F.P. Russo2|3, L. Fabris1|3, M. Senzolo2|3, P. Simioni1|3 | 1Department of Medicine; 2Gastroenterology Unit; 3University of Padova, Italy

    Elena Campello
    26-10-2026
    https://doi.org/10.4081/btvb.2026.836
    58
    PDF: 23
  • PO86 | Emicizumab in patients with moderate hemophilia A and severe bleeding phenotype: single-center real-world experience A.L. Faccini, M. Biglietto, S. Sorella, E. Crisanti, M. Antonacci, R. Mormile, R. Ciciani, E. Baldacci, C. Santoro, S. Ligia | Hematology, Department of Translational and Precision Medicine Sapienza University of Roma, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.355
    767
    PDF: 35
  • PO19 | Joint health status in patients with moderate hemophilia A: a cross-sectional multi-center study I.L. Calcaterra1, F. Picasso2, F. Valeri3, E. Baldacci4, M. Napolitano5, C. Guerrino1, E. Zanon6, C. Santoro4, S. Siragusa7, C. Martinoli2, M. Di Minno1 | 1Department of Clinical Medicine and Surgery, Regional Reference Centre for Coagulation Disorders, Federico II University, Naples; 2Department of Health Sciences “DISSAL”, Università di Genova; 3Regional Centre for Hemorrhagic and Thrombotic Diseases, AOU Città della Salute e della Scienza, Turin; 4Haematology, Department of Translational and Precision Medicine, Sapienza University, Roma; 5Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, University of Palermo and Haematology Unit and Rare Disorders Hospital “V. Cervello”, Palermo; 6Haemophilia Centre, General Medicine, Padua University Hospital, Padua; 7Department PROMISE, University of Palermo, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.279
    615
    PDF: 36
  • CS07 | Endothelial dysfunction and impaired angiogenesis in Hermansky-Pudlak syndrome (HPS) type 1: studies with endothelial colony forming cells F. Tondi1, G. Purgatorio1, C. Sgromo2, E. Giglio1, E. Petito1, E. Falcinelli1, G. Guglielmini1, A. Follenzi2, P. Gresele1, L. Bury1*, C. Olgasi3* | *Shared senior authorship; 1Department of Medicine and Surgery, Section of Internal and Cardiovascular Medicine, University of Perugia; 2Department of Health Sciences, School of Medicine, University of Piemonte Orientale, Novara; 3Department of Translational Medicine, School of Medicine, University of Piemonte Orientale, Novara, Italy

    16-09-2025
    https://doi.org/10.4081/btvb.2025.204
    309
  • PO118 | VARIATION OF EGFR IN PATIENT IN DOACS THERAPY S. Vivolo, C. Gagliardi, A. Ciampa | U.O.S.D. Centro Emostasi Aorn S. G. Moscati Avellino, Italy

    Sabrina Vivolo
    26-10-2026
    https://doi.org/10.4081/btvb.2026.934
    71
    PDF: 28
  • PO049 | WHOLE-BLOOD THROMBIN GENERATION ASSAY REVEALS HYPERCOAGULABLE STATE IN SICKLE CELL DISEASE IN STEADY STATE AND CORRELATES WITH CLINICAL EVENTS A. Bravin1, E. Campello1, A. Bertomoro1, C. Bulato1, B. Serena1, S. Toffanin1, G. Bogoni1, F. Lucente1, M.P. Boaro2, G. Reggiani2, R. Colombatti2, P. Simioni1 | 1Department of Medicine, University of Padova, Italy; 2Pediatric Hematology-Oncology and Bone Marrow Transplant Unit, Department of Woman's and Child's Health, Padova University Hospital, Italy

    Angela Bravin
    26-10-2026
    https://doi.org/10.4081/btvb.2026.865
    57
    PDF: 27
  • CO43 | Early platelet dysfunction in sepsis: an ICU pilot study S. Sorrentino1, C. Gori2, L. D’Innocenzo1, M. De Siati1, Mg. Bocci3, E. De Candia1 | 1Unit of Haemostasis and Thrombosis Diseases, Fondazione Policlinico Universitario A. Gemelli, IRCCS, Roma; 2UOC Shock & Trauma, Azienda Ospedaliera San Camillo Forlanini, Roma; 3National Institute for Infectious Diseases, Lazzaro Spallanzani, IRCCS, Roma, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.249
    669
    PDF: 24
  • PO150 | FACTOR XII DEFICIENCY IN THE SETTING OF RECURRENT THROMBOSIS AND EXTENDED VENOUS OBSTRUCTION: A CASE ANALYSIS L. Leoni1, G. Pata1, A. Domenighini1, L. Crippa2, T. D'aliberti1, G. Galimberti1, F. Paciullo1, P. Rovere Querini1 | 1Internal Medicine Unit; 2Coagulation Service Thrombosis Research Unit, IRCCS San Raffaele Scientific Institute, Milano, Italy

    Laura Leoni
    26-10-2026
    https://doi.org/10.4081/btvb.2026.966
    43
    PDF: 24
  • PO091 | RESPONSE AND CARDIOVASCULAR SAFETY OF FOSTAMATINIB IN CHRONIC IMMUNE THROMBOCYTOPENIA: A REAL WORLD ANALYSIS C. Giubbilei, G. Giustini, A. Baffioni, V. Carrai | SOD Ematologia, Azienda Universitaria Ospedaliera Careggi, Firenze, Italy

    Cristina Giubbilei
    26-10-2026
    https://doi.org/10.4081/btvb.2026.907
    52
    PDF: 24
  • PO030 | PLATELET AGGREGOMETRY AS POTENTIAL TOOL TO EVALUATE ANTI-PLATELET RESPONSE IN MYELOPROLIFERATIVE NEOPLASMS: COMPARISON OF DIFFERENT TECHNIQUES AND INITIAL RESULTS A. Galbiati, I. Bertozzi, C. Fortino, D. Regazzo, L. Gianesello, F. Sartorello, V. Azzaro, G. Saggiorato, A. Napolitano, L. Fabris, P. Simioni | Department of Medicine, University of Padova, Italy

    Alessandro Galbiati
    26-10-2026
    https://doi.org/10.4081/btvb.2026.846
    49
    PDF: 33
  • Still unmet problems with low molecular weight heparin prophylaxis of venous thromboembolism. An Italian survey

    Stefania Cavazza, Gualtiero Palareti*
    03-10-2025
    https://doi.org/10.4081/btvb.2025.177
    1465
    PDF: 317
    HTML: 214
    Supplementary: 104
  • PO33 | Whole blood hypercoagulable profiles in patients with rheumatoid arthritis L. Spiezia1, A. Giollo2, C. Samà1, A. Benetti1, L. Di Luozzo2, M. Salvato2, A. Doria2, P. Simioni1 | 1First Chair of Internal Medicine, Thrombotic and Hemorrhagic Diseases Unit, Department of Medicine, University Hospital of Padova; 2Rheumatology Unit, Department of Medicine, University Hospital of Padova, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.296
    645
    PDF: 24
  • CO21 | Viscoelastic testing in inherited bleeding disorders: a cross-sectional comparison between viscoelastic coagulation monitoring and rotational thromboelastometry C. Simion, C. Samà, C. Bulato, G. Gottardi, D. Regazzo, E. Campello, P. Simioni | Department of Medicine – DIMED, University of Padua, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.227
    662
    PDF: 27
  • PO129 | CLINICAL BENEFIT OF RECOMBINANT ADAMTS13 IN CTTP ASSOCIATED WITH HOMOZYGOUS PD173G MUTATION AND UNDETECTABLE ACTIVITY M. Sacco1, S. Lancellotti1, M. Basso1, R. De Cristofaro1|2 | 1Servizio Malattie Emorragiche e Trombotiche, Fondazione Policlinico Universitario Gemelli IRCCS, Roma, Italy; 2Dipartimento di Medicina e Chirurgia Traslazionale, Università Cattolica S. Cuore, Roma, Italy

    Raimondo De Cristofaro
    26-10-2026
    https://doi.org/10.4081/btvb.2026.945
    49
    PDF: 25
  • PO058 | IMMUNOMODULATORY EFFECTS OF FOSTAMATINIB IN A PATIENT WITH EVANS SYNDROME, TRIPLE-POSITIVE ANTIPHOSPHOLIPID ANTIBODIES AND RELATED COAGULATION ABNORMALITIES S. Bergonzi1|2|4, G. Murante1|2|4, M. Capetta1|2|4, F. Valeri1|2, C. Dainese1|2, A. Valpreda3|4, R. Pastorino3|4, F. Bocchi3|4, B. Bruno2|4, A. Borchiellini1|2 | 1Regional Centre for Hemorrhagic and Thrombotic Diseases; 2Division of Hematology; 3Central Laboratory Baldi and Riberi, AOU Città della Salute e della Scienza, Università di Torino, Italy; 4Department of Molecular Biotechnology and Health Sciences, University of Turin, Italy

    Sara Bergonzi
    26-10-2026
    https://doi.org/10.4081/btvb.2026.874
    52
    PDF: 28
  • PO004 | SEX-RELATED DIFFERENCES AND PREDICTORS OF MORTALITY IN MAJOR ORTHOPEDIC SURGERY: INSIGHTS FROM THE ORTHO-START REGISTRY A. de Laurenzo1, E. Antonucci2, C. Rostagno3, D. Barcellona4, D. Colaizzo1, G. di Rienzo5, F. Gorgoglione1, G. Maccagnano6, F. Marongiu2, M. Mastroianno1, M. Marzolo7, L. Mirabella6, B. Moretti8, A.M. Moretti9, A. Ostuni6, G. Palareti2, M. Margaglione6, E. Grandone1|6 | 1Fondazione I.R.C.C.S. “Casa Sollievo della Sofferenza”, S. Giovanni R. (Foggia), Italy; 2Fondazione Arianna, Bologna, Italy; 3Department of Internal and Postoperative Medicine, Careggi University Hospital, Firenze, Italy; 4Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy; 5UOC Patologia Clinica-Ospedale Altamura ASL Bari, Italy; 6University of Foggia, Policlinico Riuniti Foggia, Italy; 7Angiology Unit, Ospedale di Rovigo, Rovigo, Italy; 8School of Medicine, AOU Consorziale Policlinico, University of Bari "Aldo Moro", Italy; 9President of GISeG (Italian Group for Health and Gender), Bari, Italy

    Elvira Grandone
    26-10-2026
    https://doi.org/10.4081/btvb.2026.820
    48
    PDF: 24
  • PO69 | Whole blood thrombin generation hypercoagulable profile in a patient with hemolytic crisis due to paroxysmal nocturnal hemoglobinuria: a case report A. Napolitano, L. Spiezia, C. Bulato, E. Campello, P. Simioni | First Chair of Internal Medicine, Department of Medicine, University-Hospital of Padua Medical School, Padua, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.338
    718
    PDF: 25
  • CO51 | Novel biomarkers of neurological damage in acute immune-mediated thrombotic thrombocytopenic purpura A. Truma1,2, I. Mancini1, F. Verde2,3, J. A. Giannotta1, A. Artoni1, B. Ferrari1, P. Agosti1,2, M. Gagliardi1, A. Ratti3,4, N. Ticozzi2,3, F. Peyvandi1,2 | 1Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Milan; 2Università degli Studi di Milano, Department of Pathophysiology and Transplantation, Milan; 3Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan; 4Università degli Studi di Milano, Department of Medical Biotechnology and Translational Medicine, Milan, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.261
    602
    PDF: 18
  • PO105 | IMPACT OF ECOG PERFORMANCE STATUS ON CANCER-ASSOCIATED THROMBOSIS TREATED WITH DOACS: DATA FROM A MULTICENTER COHORT STUDY R. Talerico1, F. Mancinetti1, C. Sacco2, M. Mazzetti3, E. Campello4, S. Birocchi5, S. Beccatini6, A. Porfidia1, C. Lodigiani2, P. Simioni4, G.M. Podda5, I. Mastandrea2, C. Becattini6, R. Pola1, M.C. Vedovati6 | 1Thrombosis Unit, Department of Geriatric, Orthopedic, and Rheumatologic Sciences, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy; 2Thrombosis and Hemorrhagic Diseases Unit, IRCCS Humanitas Research Hospital, Rozzano, Milano, Italy; 3Interdisciplinary Internal Medicine, Careggi University Hospital, Firenze, Italy; 4First Chair of Internal Medicine and Thrombotic and Hemorrhagic Diseases Unit, Department of Medicine, University of Padova, Italy; 5Medicine II Unit, ASST Santi Paolo e Carlo, Department of Health Sciences, University of Milano, Milano, Italy; 6Internal, Vascular and Emergency Medicine– Stroke Unit, University of Perugia, Perugia, Italy

    Rosa Talerico
    26-10-2026
    https://doi.org/10.4081/btvb.2026.921
    49
    PDF: 25
  • PO040 | PHARMACODYNAMIC CHARACTERIZATION OF THROMBIN GENERATION IN SEVERE HEMOPHILIA A PATIENTS ON EMICIZUMAB PROPHYLAXIS: A REAL-WORLD LONGITUDINAL STUDY M. Bergamaschi, A. Pallotta, M. Biglietto, S. Sorella, S. Ligia, E. Baldacci, A. Chistolini, C. Santoro, R. Mormile | Department of translational and precision Medicine, Sapienza, University of Rome, Italy

    Martina Bergamaschi
    26-10-2026
    https://doi.org/10.4081/btvb.2026.856
    58
    PDF: 26
  • PO41 | Comparison of the haemorrhagic phenotype between female and male patients affected by autosomal inherited bleeding disorders in a single-centre cohort B. Borsellino1,3, C. Zuccotti2, L. Guarnera3,4, C. Biasoli5, P. Pedrazzi5, T. Martini1 | 1Haemophilia Centre, Immune-Haematology and Transfusion Medicine, University Hospital “Città della Salute e della Scienza”, Turin, Italy; 2Department of Clinical Pathology, Bufalini Hospital, Cesena, Italy; 3Department of Biomedicine and Prevention, PhD in Immunology, Molecular Medicine and Applied Biotechnology, University of Roma Tor Vergata, Roma, Italy; 4Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH, USA; 5Haemophilia and Transfusion Centre, Bufalini Hospital, Cesena, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.304
    632
    PDF: 32
  • CO32 | Major surgery in patients with severe hemophilia A without inhibitors receiving prophylaxis with fitusiran E. Zanon, C. Simion, A. Napolitano, L. Spiezia, P. Simioni | Haemophilia Center, First Chair of Internal Medicine, Department of Medicine, University-Hospital of Padua Medical School, Padua, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.239
    582
    PDF: 33
  • PO141 | PLASMA METABOLOMIC PROFILING IDENTIFIES PLATELET-RELATED METABOLIC CHANGES AFTER PFO CLOSURE IN MIGRAINE WITH AURA F. Marincola1, N. Zuddas1, F. Cannas1, A. Becchetti2, L.V. Renna3, M. Brambilla2, R. Cardani3, M. Conti2, K. Nallio2, M. Chessa3, D. Trabattoni2, V. Fanos4, M. Camera2|5 | 1Università degli Studi di Cagliari, Cagliari, Italy; 2Centro Cardiologico Monzino IRCCS, Milano, Italy; 3IRCCS Policlinico San Donato, San Donato, Milano, Italy; 4University Hospital of Cagliari, Cagliari, Italy; 5Università degli Studi di Milano, Department of Pharmaceutical Sciences, Milano, Italy

    Maria Conti
    26-10-2026
    https://doi.org/10.4081/btvb.2026.957
    58
    PDF: 21
  • PO077 | BALANCING BLEEDING AND THROMBOSIS: SAFETY OF LOW-MOLECULAR-WEIGHT HEPARIN THROMBOPROPHYLAXIS IN PATIENTS WITH HEMOPHILIA UNDERGOING MAJOR SURGERY S. Bergonzi1|2|3, G. Murante1|2|3, M. Capetta1|2|3, F. Valeri1|2, C. Dainese1|2, A. Valpreda3|4, R. Pastorino3|4, F. Bocchi3|4, B. Bruno2|3, A. Borchiellini1|2 | 1Regional Centre for Hemorrhagic and Thrombotic Diseases, AOU Città della Salute e della Scienza, Turin, Italy; 2Division of Hematology, AOU Città della Salute e della Scienza, Università di Torino, Italy; 3Department of Molecular Biotechnology and Health Sciences, University of Turin, Italy; 4Central Laboratory Baldi and Riberi, AOU Città della Salute e della Scienza, Università di Torino, Italy

    Sara Bergonzi
    26-10-2026
    https://doi.org/10.4081/btvb.2026.893
    49
    PDF: 26
  • PO019 | LONGITUDINAL COAGULATION PROFILING BY THROMBIN GENERATION AND CIRCULATING MICROVESISCLES OF INDIVIDUALS UNDERGOING GENDER-AFFIRMING HORMONE THERAPY E. Campello, A. Scala, A. Napolitano, C. Simion, C. Bulato, S. Toffanin, S. Gavasso, B. Serena, A. Montagna, A. Garolla, P. Simioni | Department of Medicine, University of Padova, Italy

    Elena Campello
    26-10-2026
    https://doi.org/10.4081/btvb.2026.835
    53
    PDF: 28
  • PO84 | Beyond the scores: unmasking a silent pulmonary embolism in essential thrombocythemia N. Battino | ASL Sulcis Iglesiente PO CTO, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.353
    659
    PDF: 21
  • PO18 | Does muscle mass matter? Appendicular lean mass as a determinant of anti-XA activity in elderly patientes B.M. Zanforlini1, V. Bernardi1, E. Campello2, E.M. Bicego1, C. Curreri1, A. Vaticano1, C. Sartori1, L. Manfron1, A. Perencin1, P. Rollo1, A. Baruffol1, L. Ruoso1, C. Simion2, C. Bulato2, P. Berto2, P. Simioni2, G. Sergi1 | 1Department of Medicine, Geriatrics Section, University of Padova; 2Haemorrhagic and Thrombotic Diseases Unit, Department of Medicine DIMED, Padova University Hospital, Padova, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.278
    614
    PDF: 21
  • CS03 | Khorana risk score and genomic profiling for prediction of venous thromboembolism in ovarian cancer P. Santini, F. Mancinetti, S.M.P. D’Ambrosio, M. Bigossi, A. D’Errico, E. Fondi, G. Fracassa, E. Ianuà, L. Mastrantoni, G. Anderson, F. Camarda, I. Marino, J. Preziosi, M. Buttarelli, M. Manfredelli, A. Minucci, F. Persiani, L. Giacò, T. Pasciuto, I. Conti, I. Mozzetta, C. Marchetti, V. Salutari, G. Scambia, C. Nero, R. Pola | Agostino Gemelli University Polyclinic Foundation IRCCS, Roma, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.200
    775
    PDF: 24
  • PO117 | LONGITUDINAL THROMBIN GENERATION PROFILING IN A PATIENT WITH SEVERE HEMOPHILIA A DURING ANTITHROMBIN-LOWERING THERAPY, CANCER, AND MAJOR SURGERY C. Simion, C. Bulato, E. Campello, E. Zanon, B. Serena, S. Toffanin, P. Simioni | Department of Medicine, University of Padova, Italy

    Chiara Simion
    26-10-2026
    https://doi.org/10.4081/btvb.2026.933
    56
    PDF: 26
  • PO048 | EFFICACY OF RITUXIMAB TREATMENT IN A CASE OF A RELAPSED AND REFRACTORY ACQUIRED VON WILLEBRAND DISEASE SECONDARY TO PRIMARY CUTANEOUS MARGINAL ZONE B-CELL LYMPHOMA L. Gurgoglione1, F. Saladino2, E. Morsia2, N. Viola3, S. Rupoli1, A. Poloni2 | 1Clinical Hematology, AOU delle Marche, Ancona, Italy; 2Università Politecnica delle Marche, Ancona, Italy; 3Clinical Immulogy, AOU delle Marche, Ancona, Italy

    Laura Gurgoglione
    26-10-2026
    https://doi.org/10.4081/btvb.2026.864
    56
    PDF: 30
  • PO49 | Use of emicizumab in two patients with acquired hemophilia A: a new therapeutic approach S. Sorella, J. Micozzi, E. Baldacci, M. Biglietto, R. Mormile, A. Chistolini, R. Ciciani, L. Torrieri, N. Zhdanovskaya, M. Lorenzon, A. Delli Paoli, S. Ligia, C. Santoro | Hematology, Department of Translational and Precision Medicine, Policlinico Umberto I, Sapienza University of Roma, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.318
    680
    PDF: 32
  • CO42 | Oxidative stress may contribute to enhanced thrombopoiesis through miR-150: implications for aspirin response R. Liani1, P.G.M. Simeone1, M. Alfonsetti1, M. Frezza1, R. Tripaldi1, S. Ciotti1, M. Luongo2, F. Cipollone1, L. Vanella3, F. Santilli1 | 1Department of Medicine and Aging, and Center for Advanced Studies and Technology “CAST”, G. d’Annunzio University of Chieti-Pescara, Chieti; 2Immunotransfusion Service, Clinical Haematology of Chieti University Hospital, Chieti; 3Department of Drug Sciences, University of Catania, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.248
    589
    PDF: 22
  • PO148 | ANALYTICAL DISCREPANCY IN PLATELET COUNTING REVEALING MYH9-RD: A CASE REPORT M. De Girolamo, A. Marrocchi, F. Vitone, M. Scapaticci, M. Bovara, T. Papillo, R. Mancini | Laboratorio Unico Metropolitano, Bologna, Italy

    Marco De Girolamo
    26-10-2026
    https://doi.org/10.4081/btvb.2026.964
    41
    PDF: 30
  • PO087 | BEYOND POSITIVITY: THE HIERARCHICAL ROLE OF IMMUNOASSAYS IN HEPARIN INDUCED THROMBOCYTOPENIA G. Murante1|2|3, S. Bergonzi1|2|3, M. Capetta1|2|3, F. Valeri1|2, C. Dainese1|2, A. Valpreda4, R. Pastorino1|3, F. Bocchi1|3, A. Porreca5, B. Bruno2|3, A. Borchiellini1|2 | 1Regional Centre for Hemorrhagic and Thrombotic Diseases, AOU Città della Salute e della Scienza di Torino, Italy; 2Division of Hematology, AOU Città della Salute e della Scienza, Università di Torino, Italy; 3Dep. of Molecular Biotechnology and Health Sciences, University of Turin, Italy; 4Central Lab. Baldi and Riberi, AOU Città della Salute e della Scienza di Torino, Italy; 5Dep. of Human Sciences and Quality of Life Promotion, Clinical and Molecular Epidemiology, IRCCS San Raffaele Roma, Italy

    Giovanni Murante
    26-10-2026
    https://doi.org/10.4081/btvb.2026.903
    62
    PDF: 24
  • PO027 | IGFBP-6 REGULATES PLATELET PROCOAGULANT ACTIVITY AT THE INTERFACE BETWEEN INFLAMMATION AND COAGULATION L. Bury1, E. Falcinelli1, E. Petito1, L. Leijonancker2, H. van Ooijen2, S. Petkov2, A.R.D. Coda3, C. Raucci1, V. Fazzi1, D. Sarnà1, C. Becattini1, P. Gresele1, A. Liso4 | 1Department of Medicine and Surgery, Section of Internal and Cardiovascular Medicine, University of Perugia, Perugia, Italy; 2Pixelgen Technologies AB, Stockholm, Sweden; 3C.R.E.A.T.E.-Center for Research and Innovation in Medicine, Department of Medical and Surgical Sciences, University of Foggia, Italy; 4Department of Medicine and Surgery, University of Perugia, Perugia and Hematology/Oncology Unit, Terni Hospital, Terni, Italy

    Loredana Bury
    26-10-2026
    https://doi.org/10.4081/btvb.2026.843
    58
    PDF: 27
  • PO32 | Effect of the sodium-glucose co-transporter-2 (SGLT2) inhibitors on platelet activation and lipid peroxidation: results of a pilot study P.G.M. Simeone1, R. Liani1, M. Alfonsetti1, B. Cancelli1, M. Frezza1, G. Raggiunti1, S. Zeeba2, F. Cipollone1, G. Renda2, F. Santilli1 | 1Department of Medicine and Aging Sciences, Center for Advanced Studies and Technology, University of Chieti; 2Department of Neuroscience, Imaging and Clinical Sciences, G. D’Annunzio University of Chieti-Pescara; 3University Cardiology Division, Heart Department, Policlinico SS Annunziata, Chieti, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.293
    623
    PDF: 23
  • CO19 | Hypercoagulability in wild-type transthyretin amyloidosis: evidence from whole blood thromboelastometry A. Napolitano1, L. Spiezia1, C. Samà1, A. Benetti1, G. Sinigiani2, L. De Michieli2, A. Cipriani2, P. Simioni1 | 1First Chair of Internal Medicine, Department of Medicine, University Hospital of Padua; 2Department of Cardiothoracic and Vascular Sciences & Public Health, University Hospital of Padua, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.223
    612
    PDF: 21
  • PO128 | FROM SEVERE THROMBOSIS TO SUCCESSFUL PREGNANCIES: ORTHOTOPIC LIVER TRANSPLANTATION IN INHERITED AFIBRINOGENEMIA WITH BUDD–CHIARI SYNDROME G. Murante1|2|6, S. Bergonzi1|2|6, M. Capetta1|2|6, F. Valeri1|2, C. Dainese1|2, A. Valpreda4, R. Pastorino1|6, F. Bocchi1|6, R. Romagnoli5, S. Martini3, B. Bruno2|6, A. Borchiellini1|2 | 1Regional Centre for Hemorrhagic and Thrombotic Diseases; 2Division of Hematology; 3SSD Hepatic insufficiency and Liver Transplant; 4Central Lab. Baldi and Riberi; 5General Surgery 2U - Liver Transplant Center, Molinette Hospital, AOU Città della Salute e della Scienza di Torino, Italy; 6Dep. of Molecular Biotechnology and Health Sciences, University of Turin, Italy

    Giovanni Murante
    26-10-2026
    https://doi.org/10.4081/btvb.2026.944
    48
    PDF: 27
  • PO056 | SYNERGISTIC EFFECT OF RECOMBINANT FACTOR INFUSION ON THROMBIN GENERATION IN HEMOPHILIA PATIENTS UNDER EMICIZUMAB OR CONCIZUMAB PROPHYLAXIS F. Bocchi1|2, R. Pastorino1|2, M. Capetta1|2|3, S. Bergonzi1|2|3, G. Murante1|2|3, F. Valeri2|3, C. Dainese2|3, A. Valpreda4, B. Bruno1|3, A. Borchiellini2|3 | 1Department of Molecular Biotechnology and Health Sciences, University of Turin, Italy; 2Regional Center for Thrombotic and Hemorrhagic Diseases; 3Division of Hematology; 4Central Lab Baldi and Riberi, AOU Città della Salute e della Scienza di Torino, Italy

    Matilde Capetta
    26-10-2026
    https://doi.org/10.4081/btvb.2026.872
    62
    PDF: 27
  • PO001 | EMERGENCY DEPARTMENT MANAGEMENT OF PULMONARY EMBOLISM IN CANCER PATIENTS: PROGNOSTIC STRATIFICATION AND OUTCOMES A. Decursu1, L. Galli2, LM. Caiano2, S. Bozzato2, E. Ruggeri1, F. Paletta3, L. Vulcano1, L. Bertù1, F. Cortellaro2, W. Ageno4, MP. Donadini1|2 | 1Università degli studi dell'Insubria, Italy; 2ASST Sette Laghi, Italy; 3Università degli studi di Milano-Bicocca, Italy; 4Università degli studi di Padova, Italy

    Alessandro Decursu
    26-10-2026
    https://doi.org/10.4081/btvb.2026.817
    53
    PDF: 23
  • PO68 | Whole blood hypercoagulable profiles in a patient with markedly elevated lipoprotein(A) plasma levels and thrombotic complications: a case report C. Portinari, M. Biolo, A. Napolitano, L. Spiezia, A. Colpo, S. Zambon, A. Zambon, P. Simioni | Department of Medicine, Padova University Hospital, Padova, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.337
    658
    PDF: 32
  • CO50 | Diagnostic accuracy of the heparin-induced multiple electrode aggregometry (HIMEA) functional test for heparin-induced thrombocytopenia M. Bovara1, M. Sebastiani2, Am. Gori3,4, A. Rogolino3,4, A. Bertelli3,4, G. Ciarrocca Taranta3,4, R. Marcucci3,4, M. Sartori5, B. Cosmi5, M. Silingardi6, A. M. Pizzini6, A. Marrocchi1, R. Mancini1 | 1Laboratorio Unico Metropolitano Ospedale Maggiore, AUSL Bologna; 2IRCCS Istituto delle Scienze Neurologiche, Bologna; 3Centro Malattie Aterotrombotiche Azienda Ospedaliera Universitaria Careggi, Firenze; 4Dipartimento di Medicina Sperimentale e Clinica, Università di Firenze; 5U.O. di Angiologia e Malattie della Coagulazione dell’Azienda Ospedaliero Universitaria Policlinico S. Orsola-Malpighi, Bologna; 6Medicina Interna Ospedale Maggiore, Bologna, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.260
    638
    PDF: 25
  • PO104 | BLEEDING AND THROMBOTIC OUTCOMES DURING EXTENDED DIRECT ORAL ANTICOAGULANT THERAPY: AN EIGHT YEAR RETROSPECTIVE ANALYSIS G. Sottilotta1, G. Praticò1, S. Cuzzocrea1, D. Megalizzi1, F. Luise2 | 1UOSD Microcitemie - Emostasi e Trombosi. Grande Ospedale Metropolitano di Reggio Calabria, Italy; 2Laboratorio Analisi. Grande Ospedale Metropolitano di Reggio Calabria, Italy

    Gianluca Sottilotta
    26-10-2026
    https://doi.org/10.4081/btvb.2026.920
    69
    PDF: 27
  • PO037 | TEMPO: A MOBILE HEALTH APPLICATION FOR PERSONALIZED MANAGEMENT OF HEMOPHILIA R. Gualtierotti1|2, F. Franco3, L. Bedogni4, M. Fassi1, A.A Giachi1, S. Mascetti5, M. Manzoni5, F. Poggi6, M. Pellegrini6, C. Suffritti1, F. Peyvandi1|2 | 1Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Milano, Italy; 2Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milano, Italy; 3Department of Physics, Informatics and Mathematics (FIM), University of Modena and Reggio Emilia, Modena, Italy; 4Department of Sciences and Method for Engineering (DISMI), University of Modena and Reggio Emilia, Modena, Italy; 5Department of Computer Science, Università degli Studi di Milano, Milano, Italy; 6Institute for Cognitive Sciences and Technologies (ISTC), National Research Council (CNR), Bologna, Italy

    Marco Fassi
    26-10-2026
    https://doi.org/10.4081/btvb.2026.853
    73
    PDF: 34
  • PO40 | Management of paediatric patients affected by mild factor VII deficiency undergoing surgery B. Borsellino1,2, B. Pollio1, I. Ricca1, R. Albiani1, T. Martini1 | 1Haemophilia Centre, Immune-Haematology and Transfusion Medicine, University Hospital “Città della Salute e della Scienza”, Turin; 2Department of Biomedicine and Prevention, PhD in Immunology, Molecular Medicine and Applied Biotechnology, University of Roma Tor Vergata, Roma, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.303
    584
    PDF: 17
  • CO30 | Joint prosthetic surgery in patients with hemophilia A: clinical-functional outcomes and quality of life E. Zanon1, A. Napolitano1, A. Berizzi2, P. Simioni1 | 1Haemophilia Center, First Chair of Internal Medicine, Department of Medicine, University-Hospital of Padua Medical School, Padua; 2Orthopedics and Traumatology Unit, University-Hospital of Padua Medical School, Padua, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.236
    708
    PDF: 41
  • PO140 | HISTORY OF FALLS IN PATIENTS WITH ATRIAL FIBRILLATION: A SYSTEMATIC REVIEW AND META-ANALYSIS A.P. Speziale1, G. Buoninfante1, A. Ronca2|4, B. Corica3, V. Trapani1, M. Moretti1, G. Annecchini1, R. Cangemi1, V. Raparelli1, M. Proietti2|4, S. Basili1, G.F. Romiti5 | 1Department of Translational and Precision Medicine, Sapienza University of Roma, Roma, Italy; 2Department of Clinical Sciences and Community Health, University of Milano, Milano, Italy; 3University of Modena and Reggio Emilia, Modena, Italy; 4Division of Subacute Care, IRCCS Istituti Clinici Scientifici Maugeri, Milano, Italy; 5Department of Wellbeing, Health and Environmental Sustainability, Sapienza University of Roma, Rieti, Italy

    Angela Pia Speziale
    26-10-2026
    https://doi.org/10.4081/btvb.2026.956
    45
    PDF: 23
  • PO075 | HEMOSTATIC AND CARDIOVASCULAR PROFILES IN HEMOPHILIA PATIENTS WITH AND WITHOUT ATHEROSCLEROSIS A. Napolitano, E. Zanon, L. Spiezia, G. Camporese, P. Scarinzi, F. Ahmad, G. Saggiorato, C. Bulato, F. Sartorello, S. Toffanin, A. Montagna, V. Azzaro, C. Simion, E. Campello, P. Simioni | Department of Medicine, University of Padova, Italy

    Angela Napolitano
    26-10-2026
    https://doi.org/10.4081/btvb.2026.891
    45
    PDF: 23
  • PO015 | OSA VS. CHA FOR RPFVIII MEASURE: STILL AN ISSUE? G. Gazzelli, Y. Azzanelli, C. Vernarecci, F. Marotta, F. Giacopelli, B. Tappino, L. Banov, A.C. Molinari | IRCCS Istituto Giannina Gaslini Genova, Italy

    Angelo Claudio Molinari
    26-10-2026
    https://doi.org/10.4081/btvb.2026.831
    58
    PDF: 23
  • PO82 | Retrospective application of the TH2 score in a multicenter cohort of ITP patients: a reliable predictive tool or a score in need of refinement? C. Giubbilei1, M. Defina2, S. Rosati3, M. Rocco3, A. Votto4, F. Simonetti5, F. Paoletti6, V. Carrai1 | 1Hematology Unit, AOU Careggi; 2Hematology unit AOU Senese; 3Hematology Unit Azienda Sanitaria Toscana Centro; 4Hematology Unit, AOU Pisana; 5Hematology Unit, Ospedale Versilia; 6Hematology Unit, Azienda Sanitaria Nord Ovest, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.351
    584
    PDF: 23
  • PO16 | Antithrombotic treatment and outcomes in retinal vein occlusion: a retrospective cohort study and comparison with historical group S.A. Malerba1,2, M.T. Sartori1, G. Libralon1, C. Dalla Porta1, P. Simioni1 | 1First Medical Clinic, Department of medicine- DIMED, Università degli Studi di Padova; 2Medicina Generale, Ospedale dell’Angelo, Mestre, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.277
    625
    PDF: 21
  • CO01 | Statin therapy for the prevention of venous thromboembolism in cancer patients: a systematic review and meta-analysis F. Catalani, R. Del Giorno, R. Canevascini, W. Ageno, L. Gabutti, G. Prouse, L. Giovannacci | Ospedale Regionale di Bellinzona, Switzerland.

    22-10-2025
    https://doi.org/10.4081/btvb.2025.199
    715
    PDF: 22
  • PO113 | A STRANGE CASE OF RECURRENT ISOLATED DIGITAL ARTERIAL THROMBOSIS M.M. Poggi, D. Bruni | SOC Medicina 1, Nuovo Ospedale Prato, Prato, Italy

    Matteo Maria Poggi
    26-10-2026
    https://doi.org/10.4081/btvb.2026.929
    46
    PDF: 29
  • PO047 | TRANSIENT IDIOPHATIC ACQUIRED VON WILLEBRAND SYNDROME: A RARE CHALLENGING CONDITION WITH A POSSIBLE RAPIDLY AND FAVOURABLE EVOLUTION G. Murante1|2|4, S. Bergonzi1|2|4, M. Capetta1|2|4, F. Valeri1|2, C. Dainese1|2, A. Valpreda3, R. Pastorino1|4, F. Bocchi1|4, B. Bruno2|4, A. Borchiellini1|2 | 1Regional Centre for Hemorrhagic and Thrombotic Diseases; 2Division of Hematology; 3Central Lab. Baldi and Riberi, AOU Città della Salute e della Scienza di Torino, Italy; 4Dep. of Molecular Biotechnology and Health Sciences, University of Turin, Italy

    Giovanni Murante
    26-10-2026
    https://doi.org/10.4081/btvb.2026.863
    59
    PDF: 22
  • In this issue

    Giovanni de Gaetano, Chiara Cerletti
    18-03-2026
    https://doi.org/10.4081/btvb.2026.472
    372
    PDF: 107
  • PO48 | Thrombotic risk evaluation and thrombophilia testing in β-thalassemia patients: a retrospective cohort analysis from a reference regional center G.M. Camarda1,2*, S. Raso1*, R. Di Maggio1, M. Vinciguerra3, A. Giangreco1, A. Inzerillo1, A. Maggio, M. Napolitano1,2 | *These authors contributed equally to this abstract; 1Hematology and Rare Diseases Unit, Azienda Ospedaliera Ospedali Riuniti Villa Sofia-Cervello, Palermo; 2Division of Hematology Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties “ProMISE”, Palermo; 3UOSD Molecular Diagnosis of Rare Blood Diseases, Azienda Ospedaliera, Ospedali Riuniti Villa Sofia, Cervello, Palermo, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.317
    673
    PDF: 39
  • CO39 | Artificial intelligence in hemophilia management: challenging the need for experts G. Sottilotta1, D. Megalizzi1, F. Luise2 | 1UOSD Microcitemie - Emostasi e Trombosi. Grande Ospedale Metropolitano Bianchi-Melacrino-Morelli, Reggio Calabria; 2Laboratorio Analisi, Grande Ospedale Metropolitano Bianchi-Melacrino-Morelli, Reggio Calabria, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.246
    629
    PDF: 21
  • PO147 | FEBRILE BILATERAL PULMONARY EMBOLISM IN A YOUNG ADULT WITH PFAPA SYNDROME: A POSSIBLE PROTHROMBO-INFLAMMATORY CONTRIBUTOR IN A MULTIFACTORIAL EVENT A. Dal Corso | Internal Medicine and Vascular Medicine, Pederzoli Hospital, Peschiera del Garda, Verona, Italy

    Alessandro Dal Corso
    26-10-2026
    https://doi.org/10.4081/btvb.2026.963
    46
    PDF: 22
  • PO086 | INHERITED PLATELET GPIV DEFICIENCY: FIRST DESCRIPTION OF TWO PATIENTS WITH BLEEDING DIATHESIS L. Bury1, S. Sorrentino2, E. Falcinelli1, G. Guglielmini1, V. Fazzi1, A. Ferretti2, P. Concolino3|4, F. Cirillo5, P. Gresele1, E. De Candia2|6 | 1Department of Medicine and Surgery, Section of Internal and Cardiovascular Medicine, University of Perugia, Perugia, Italy; 2Dipartimento di Medicina e Chirurgia Traslazionale, Università Cattolica del Sacro Cuore, Facoltà di Medicina, Roma, Italy; 3Departmental Unit of Molecular and Genomic Diagnostics, Fondazione Policlinico Gemelli IRCCS, Roma, Italy; 4Genomics Core Facility, G-STeP, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Roma, Italy; 5Department of Clinical Medicine and Surgery, Federico II University of Naples, Naples, Italy; 6Dipartimento di Scienze di Laboratorio ed Ematologiche, Policlinico Universitario A. Gemelli IRCCS, Roma, Italy. L. Bury first authorship, P. Gresele senior authorship

    Loredana Bury
    26-10-2026
    https://doi.org/10.4081/btvb.2026.902
    63
    PDF: 26
  • PO026 | AUTOSOMAL DOMINANT ITGA2B AND ITGB3 VARIANTS EXPAND THE PHENOTYPIC SPECTRUM OF ΑIIBΒ3-RELATED PLATELET DISORDERS S. Ferrari, D. Regazzo, L. Onorati, A. Galbiati, L. Spiezia, A. Bertomoro, P. Simioni | Department of Medicine, University of Padova, Italy

    Silvia Ferrari
    26-10-2026
    https://doi.org/10.4081/btvb.2026.842
    58
    PDF: 26
  • PO31 | Comparative analysis of anticoagulant therapy in patients over 90 years old: vitamin K antagonists versus direct oral anticoagulants G. Sottilotta1, P. Arrigo2, S. Cuzzocrea1, D. Megalizzi1, F. Luise3 | 1UOSD Microcitemie, Emostasi e Trombosi, Grande Ospedale Metropolitano di Reggio Calabria; 2Associazione Italiana Pazienti Anticoagulati, Sezione di Reggio Calabria; 3Laboratorio Analisi. Grande Ospedale Metropolitano di Reggio Calabria, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.292
    611
    PDF: 22
  • CO17 | Clinical relevance of isolated anti-phosphatidylserine/ prothrombin antibody positivity A. Hoxha1, P. Žigon2,3, L. Katja2,3, S. Čučnik2,4, Ž. Rotar2,5, S. Gavasso1, P. Zerbinati1, G. Gobbo1, P. Simioni1 | 1University of Padua, Internal Medicine Unit, Thrombotic and Hemorrhagic Centre, Department of Medicine-DIMED, Padua, Italy; 2University Medical Centre Ljubljana, Department of Rheumatology, Ljubljana, Slovenia; 3University of Primorska, Faculty of Mathematics, Natural Sciences and Information Technologies, Koper, Slovenia; 4University of Ljubljana, Faculty of Pharmacy, Ljubljana, Slovenia; 5University of Ljubljana, Faculty of Medicine, Ljubljana, Slovenia

    22-10-2025
    https://doi.org/10.4081/btvb.2025.221
    652
    PDF: 30
  • PO124 | BLEEDING COMPLICATIONS DURING ANTICOAGULATION WITH DOACS FOR NVAF AND THEIR MOST COMMON RISK FACTORS A. delle Femine, P. Di Micco, P. Sommese, M. Di Napoli, A. Di Salvatore, M. Galdiero, A. Lobasso, R. Serpico, V. Brunelli, A. Di Fusco, C. di Gennaro | U.O.C. Medicina Interna, Osp. Santa Maria delle Grazie, Pozzuoli, Italy

    Augusto Delle Femine
    26-10-2026
    https://doi.org/10.4081/btvb.2026.940
    45
    PDF: 22
  • PO055 | THROMBIN GENERATION PROFILES IN PATIENTS WITH WILD-TYPE TRANSTHYRETIN AMYLOIDOSIS L. Spiezia1, A. Napolitano1, C. Bulato1, S. Toffanin1, A. Benetti1, C. Samà1, L. De Michieli2, G. Sinigiani2, A. Cipriani2, P. Simioni1 | 1Dipartimento di Medicina, Azienda Osp. Università di Padova, Italy; 2Dipartimento di Scienze cardio toraco vascolari, Azienda Osp. Università di Padova, Italy

    Luca Spiezia
    26-10-2026
    https://doi.org/10.4081/btvb.2026.871
    48
    PDF: 26
  • PO66 | Viscoelastic tests in disseminated intravascular coagulation associated with aortic aneurysm A. M. Pizzini1, C. Biasoli2, M. Bovara3, E. Gesuete1, A. Fusco1, C. Fantoni1, P. Pedrazzi2, R. Mancini3, M. Silingardi1 | 1Ambulatorio Emostasi & Trombosi, Dipartimento Medico, Ospedale Maggiore AUSL Bologna; 2SSI Presa in Carico delle Malattie Emorragiche e Tromboemboliche della Romagna; 3Laboratorio Unico Metropolitano AUSL Bologna, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.335
    671
    PDF: 26
  • CO49 | The burden of cerebral small vessel disease in ITTP patients from acute phase to remission A. Truma1,2, F. M. Lo Russo1, G. Conte1,2, I. Mancini1, M. Abbattista1, J. A. Giannotta1, A. Artoni1, B. Ferrari1, P. Agosti1,2, F. M. Triulzi1,2, F. Peyvandi1,2 | 1Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Milan; 2Università degli Studi di Milano, Department of Pathophysiology and Transplantation, Milan, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.259
    645
    PDF: 26
  • PO100 | PREVALENCE OF CODING-REGION VARIANTS IN THE PROC GENE IN A SINGLE-CENTER COHORT OF PC-DEFICIENT SUBJECTS F. Ramundo, T. Malara, M. Rossi, T. Za, AM. Ciminello, S. Betti, F. Bartolomei, F. Di Landro, P. Arcuri, P. Chiusolo, V. De Stefano, E. Rossi | Catholic University, Fondazione Policlinico A.Gemelli IRCCS, Italy

    Francesco Ramundo
    26-10-2026
    https://doi.org/10.4081/btvb.2026.916
    44
    PDF: 24
  • PO035 | ASSESSMENT OF HIGH-ON-TREATMENT PLATELET REACTIVITY IN PATIENTS ON DUAL ANTIPLATELET THERAPY USING THE FULLY AUTOMATED COAGULATION ANALYZER SYSMEX CN-6500: A COMPARATIVE STUDY WITH THREE POINT-OF-CARE TESTS E. Falcinelli1, L. Bury1, E. Giglio1, A.M. Mezzasoma1, V. Fazzi1, M. del Pinto2, M. Lenti3, A. Rechner2, P. Gresele1 | 1Dept of Medicine and Surgery, Section of Internal and Cardiovascular Medicine; 2Dept. of Cardiology; 3Dept of Vascular Surgery, University of Perugia, Italy; 4Sysmex Europe

    Emanuela Falcinelli
    26-10-2026
    https://doi.org/10.4081/btvb.2026.851
    62
    PDF: 24
  • CO-51 | HEMOSTATIC AND CARDIOVASCULAR PROFILES IN HEMOPHILIA PATIENTS WITH AND WITHOUT ATHEROSCLEROSIS A. Napolitano, E. Zanon, L. Spiezia, G. Camporese, P. Scarinzi, F. Ahmad, G. Saggiorato, C. Bulato, S. Toffanin, S. Gavasso, F. Sartorello, C. Simion, E. Campello, P. Simioni | Hemophilia Center, University Hospital of Padua, Italy

    Angela Napolitano
    14-10-2026
    https://doi.org/10.4081/btvb.2026.661
    57
    PDF: 20
  • PO38 | Rates of hemorrhagic events and hemodialysis circuit thrombosis in patients with end-stage renal disease on hemodialytic treatment receiving a factor-XI inhibitor: a systematic review and meta-analysis D. Santagata, G. Barbui, M.P. Donadini, A. Squizzato | Department of Medicine and Surgery, Research Center on Thromboembolic Disorders and Antithrombotic Therapies, University of Insubria, Varese and Como, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.301
    629
    PDF: 37
  • CO27 | Intracerebral hemorrhage in hemophilia A and B: a 10-year prospective multicenter study in Italy (2012–2022) E. Zanon1, A. Napolitano1, A. Porreca2, F. Demartis3, A. Coppola4, C. Santoro5, I. Cantori6, A. C. Molinari7, C. Biasioli8, M. Luciani9, G. Sottilotta10, B. Pollio11, A. Borchiellini12, A. Tosetto13, P. Flora14, P. Simioni1 | 1Haemophilia Center, First Chair of Internal Medicine, Department of Medicine, University-Hospital of Padua Medical School, Padua; 2Department of Human Sciences and Promotion of the Quality of Life, Unit of Clinical and Molecular Epidemiology IRCCS San Raffaele Roma Open University, Roma; Unit of Clinical and Molecular Epidemiology IRCCS San Raffaele, Roma; 3Centre for Bleeding Disorders, Careggi University Hospital of Firenze; 4Azienda Ospedaliero Universitaria di Parma; 5Hematology Division, Umberto I University Hospital of Roma; 6Haemophilia Center, Department of Transfusion Medicine, Hospital of Macerata; 7IRCCS Istituto Giannina Gaslini, Genova; 8Haemophilia and Transfusion Centre, Bufalini Hospital, Cesena; 9Children’s Hospital Bambino Gesù, Roma; 10Haemophilia Center, Department of Onco-Hematology and Radioterapy, Hospital of Reggio Calabria; 11Haemophilia Pediatric Center, Transfusion Medicine, City of Health and Science of Turin; 12City of Health and Science of Turin; 13Hemorrhagic and Thrombotic Diseases Unit, S. Bortolo Hospital of Vicenza; 14RCCS Foundation Ca’ Granda Maggiore Policlinico Hospital, Milan, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.233
    712
    PDF: 42
  • PO139 | PFO-LIKE INTRACARDIAC FLOW IS SUFFICIENT TO INDUCE A PROTHROMBOTIC PLATELET PHENOTYPE: EVIDENCE FROM A MICROFLUIDIC MODEL OF PATENT FORAMEN OVALE M. Conti1, V. Guadagno2, D. Trabattoni1, A. Becchetti1, F. Morelli2, L. Fusini1, M. Brambilla1, S. Bozzi2, A. Redaelli2, M. Camera1|3 | 1Centro Cardiologico Monzino IRCCS, Milano, Italy; 2Politecnico di Milano, Department of Electronics, Informatics and Bioengineering (DEIB), Milano, Italy; 3Università degli Studi di Milano, Department of Pharmaceutical Sciences, Milano, Italy

    Maria Conti
    26-10-2026
    https://doi.org/10.4081/btvb.2026.955
    62
    PDF: 32
  • PO067 | LONG‑TERM SAFETY AND EFFECTIVENESS OF VITAMIN K ANTAGONISTS IN PATIENTS WITH ANTIPHOSPHOLIPID ANTIBODIES: A RETROSPECTIVE COHORT ANALYSIS G. Sottilotta1, G. Praticò1, D. Megalizzi1, F. Luise2 | 1UOSD Centro per le Microcitemie - Servizio Emostasi e Trombosi; 2Laboratorio Analisi, Grande Ospedale Metropolitano di Reggio Calabria, Italy

    Gianluca Sottilotta
    26-10-2026
    https://doi.org/10.4081/btvb.2026.883
    49
    PDF: 27
  • PO009 | THROMBOPHILIA AND ASSISTED REPRODUCTIVE TECHNOLOGY: PRELIMINARY RESULTS FROM A SINGLE CENTER RETROSPECTIVE COHORT STUDY G. Burrei2, E. Malloggi1, S. Moruzzi1, L. Delfino1, F. Pizzolo1, L. Panepinto1, F. Presa1, C. Spillere1, A. Moschella1, F. Zoccatelli1, S. Friso1, N. Martinelli1, S. Suardi1 | 1Department of Medicine, University Hospital, Verona, Italy; 2General Medicine Unit, Magalini Hospital, Villafranca di Verona, Italy

    Giulia Burrei
    26-10-2026
    https://doi.org/10.4081/btvb.2026.825
    78
    PDF: 28
  • PO28 | CLINICAL IMPLICATIONS OF ANTICOAGULANT DRUG INTERACTIONS WITH TARGETED AND IMMUNE THERAPIES IN ONCOLOGY: A CONTEMPORARY RISK STRATIFICATION FRAMEWORK D. Dhami1, C. Solowiej Singh 1, M. Dhami 2 | 1Abrazo Internal Medicine Residency; 2Eastern Connecticut Hematology Oncology, Norwich, CT, USA

    ICTHIC 2026
    16-04-2026
    https://doi.org/10.4081/btvb.2026.523
    598
    PDF: 106
  • PO81 | Direct oral anticoagulants in atypical site vein thrombosis: a single centre experience focused on cancer patients U. Mazzarelli1, A. Guida1, L. Agrelli1, M. Amato1, R. Guarrasi2, L. Santaniello2, C. Cardamone1, P. Vitale1, M. Triggiani1 | 1Centro per le Malattie Emorragiche Congenite e Malattie Trombotiche UOC Clinica Immunologica e Reumatologica AOU S. Giovanni di Dio e Ruggi d’Aragona, Salerno; 2UOC Clinica Oncologica AOU S. Giovanni di Dio e Ruggi d’Aragona, Salerno, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.350
    650
    PDF: 33
  • PO15 | Venous thromboembolism risk associated with midline catheters and peripherally inserted central catheters: a systematic review and meta-analysis D. Santagata1, F. Subri1, F. Dentali1,2, M.P. Donadini1, I. Giarretta2 | 1Department of Medicine and Surgery, Research Center on Thromboembolic Disorders and Antithrombotic Therapies, University of Insubria, Varese and Como; 2Department of Internal Medicine, Ospedale di Circolo and Fondazione Macchi, Varese, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.276
    597
    PDF: 25
  • PO112 | REFRAMING THE ENIGMA: ACQUIRED HEMOPHILIA A AS A HARBINGER OF HHV-8–ASSOCIATED MULTICENTRIC CASTLEMAN DISEASE M. Palladino1, G. Gammaitoni1, C. Santoro2, M. Muscaritoli1 | 1Medicina Interna e Nutrizione Clinica-Dip. Medicina Traslazionale e di Precisione; 2Ematologia- Dip. Medicina Traslazionale e di Precisione, Umberto I Roma, Italy

    Mariangela Palladino
    26-10-2026
    https://doi.org/10.4081/btvb.2026.928
    48
    PDF: 29
  • PO046 | BLEEDING PHENOTYPE AND PLATELET FUNCTION TESTS IN BERNARD-SOULIER SYNDROME: A CORRELATION STUDY L. Onorati, S. Ferrari, D. Regazzo, A. Galbiati, A. Cerbo, L. Gianesello, C. Samà, A. Bertomoro, L. Spiezia, P. Simioni | Dipartimento di Medicina, Azienda Osp. Università di Padova, Italy

    Luca Spiezia
    26-10-2026
    https://doi.org/10.4081/btvb.2026.862
    58
    PDF: 25
  • BEST-03 | CRISPR-CAS9 CORRECTION IN SEVERE HEMOPHILIA A A. Benetti1, C.M. Radu1, M. Trevisan2, C. Samà1, C. Simion1, E. Campello1, P. Simioni1 | 1First Chair of Internal Medicine and Thrombotic and Haemorrhagic Diseases Unit, Department of Medicine, Padova University Hospital, Italy; 2Department of Molecular Medicine, University of Padua, Italy

    Andrea Benetti
    14-10-2026
    https://doi.org/10.4081/btvb.2026.603
    149
    PDF: 26
  • Cardiovascular risk in hormone replacement therapy

    Doris Barcellona
    09-02-2026
    https://doi.org/10.4081/btvb.2026.411
    2730
    PDF: 361
  • PO47 | Hemophilia A and antithrombin deficiency: a case of natural hemostatic rebalancing L. Torrieri, S. Ligia, E. Baldacci, R. Mormile, S. Sorella, R. Ciciani, M. Biglietto, N. Zhdanovskaya, A. Delli Paoli, A. Tirnetta, M. Lorenzon, C. Santoro | Hematology, Department of Translational and Precision Medicine, Policlinico Umberto I, Sapienza University of Roma, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.316
    653
    PDF: 20
  • CO36 | Inhibitor titer at diagnosis and clinical course in acquired hemophilia A: a single-center experience C. Simion, B. Stocco, E. Dalla Porta, E. Campello, G. Furlan, L. Spiezia, G. Saggiorato, F. Sartorello, E. Zanon, P. Simioni | Department of Medicine – DIMED, University of Padua, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.243
    601
    PDF: 41
  • PO146 | COMPARISON OF COAGULATION AND CHROMOGENIC METHODS IN PHARMACOKINETICS WITH EXTENDED HALF-LIFE FACTOR VIII R. Pastorino1|2, F. Bocchi1|2, G. Murante1|2|3, S. Bergonzi1|2|3, M. Capetta1|2|3, F. Valeri2|3, C. Dainese2|3, A. Valpreda4, B. Bruno1|3, A. Borchiellini2|3 | 1Department of Molecular Biotechnology and Health Sciences, University of Turin, Torino, Italy; 2Regional Centre for Thrombotic and Hemorrhagic Diseases; 3Division of Hematology; 4Central Lab Baldi and Riberi, AOU Città della salute e della Scienza di Torino, Torino, Italy

    Rebecca Pastorino
    26-10-2026
    https://doi.org/10.4081/btvb.2026.962
    64
    PDF: 24
  • PO083 | WOMEN AND HEMOPHILIA: ASSESSMENT OF THE BLEEDING PHENOTYPE – ANALYSIS OF THE BRESCIA COHORT N. Portesi, S. Pontoglio, G. Carracchia, G. Albrici, E. Bertoni, G. Martini | ASST Spedali Civili di Brescia, Italy

    Nicola Portesi
    26-10-2026
    https://doi.org/10.4081/btvb.2026.899
    48
    PDF: 24
  • PO025 | CHARACTERIZATION OF PLATELET DYSFUNCTION IN NOONAN SYNDROME PATIENTS S. Sorrentino1, I. Lazzareschi2, A. Ferretti1, R. Onesimo2, A. Romano3, G. Zampino2, C. Leoni2, E. De Candia1 | 1UOS Piastrinopenie Congenite e Piastrinopatie, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Roma, Italy; 2UOC Pediatria, Fondazione Policlinico Universitario Agostino Gemelli IRCSS, Roma, Italy; 3UOC Oncologia Pediatrica, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Roma, Italy

    Silvia Sorrentino
    26-10-2026
    https://doi.org/10.4081/btvb.2026.841
    47
    PDF: 26
  • PO25 | Baseline thrombin generation test does not predict thrombotic events in acute leukemia: a monocentric prospective study M. Biglietto, R. Mormile, M.L. Bisegna, A. Laganà, A. L. Faccini, A. Papa, E. Baldacci, C. Santoro, M.S. De Propris, A. Chistolini | Hematology, Department of Translational and Precision Medicine Sapienza University of Roma, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.286
    672
    PDF: 22
  • CO15 | Longitudinal coagulation profiling of individuals undergoing gender-affirming hormone therapy: the hyper-gender study A. Napolitano, E. Campello, A. Scala, C. Simion, C. Bulato, S. Gavasso, C. Samà, A. Benetti, S. Toffanin, G. Faggian, R. Scafa, A. Garolla, P. Simioni | First Chair of Internal Medicine, Department of Medicine, University Hospital of Padua; Unit of Andrology and Reproductive Medicine, Department of Medicine, University Hospital of Padua, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.219
    692
    PDF: 24
  • PO123 | PERIOPERATIVE MANAGEMENT OF FEMORAL FRACTURE SURGERY IN AN ELDERLY PATIENT WITH ACQUIRED HEMOPHILIA A RECEIVING EMICIZUMAB C. Simion, E. Zanon, B. Stocco, G. Saggiorato, F. Sartorello, C. Bulato, P. Simioni | Department of Medicine, University of Padova, Italy

    Chiara Simion
    26-10-2026
    https://doi.org/10.4081/btvb.2026.939
    53
    PDF: 21
  • PO053 | PLATELET AGGREGATION AND THROMBIN GENERATION IN MULTIPLE MYELOMA: A PROSPECTIVE STUDY M. Biglietto, M. Mormile, A. Piciocchi, F. Fazio, M. Capriata, S. Sorella, E. Baldacci, A. Chistolini, M.T. Petrucci, C. Santoro | Sapienza University of Roma, Italy

    Mario Biglietto
    26-10-2026
    https://doi.org/10.4081/btvb.2026.869
    65
    PDF: 31
  • PO65 | Utilization of emicizumab in acquired hemophilia A: a case report C. Caputo, P. Conca, I.L. Calcaterra, E. Cimino, M. Romeo, M. Aversano, E. Franco, C. De Luca, G. D’errico, L. Jr Valletta, M. Di Minno, A. Tufano | Department of Clinical Medicine and Surgery, Federico II University, Naples, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.334
    642
    PDF: 36
  • CO47 | Genetic characterization of the KIV2 LPA polymorphism in subjects with bicuspid aortic valve with different clinical complications R. Orsi1, G. Barbieri1, E. Sticchi1,2, A. Kura1, L. Squillantini1, P. Cantini1, A. Rogolino2, M. Berteotti1,2, S. Nistri3, P. Stefàno4, R. Marcucci1,2, B. Giusti1,2 | 1Department of Experimental and Clinical Medicine, University of Firenze; 2Centre for Atherothrombotic Diseases, AOU Careggi, Firenze; 3Cardiology, CMSR Veneto Medica, Altavilla Vicentina; 4Cardiac Surgery, AOU-Careggi, Firenze, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.257
    634
    PDF: 23
  • PO158 | A RARE CASE OF ISCHEMIC STROKE: CAROTID WEBS C. Mazzei, I. Costanzo, D. Fumarulo, S. Bernardi, G. Trinchera, M. Littera, M. Mazzetti, C. Tamburini | Medicina Interna Interdisciplinare, A.O.U. Careggi, Firenze, Italy

    Chiara Mazzei
    26-10-2026
    https://doi.org/10.4081/btvb.2026.974
    83
    PDF: 27
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Bleeding, Thrombosis and Vascular Biology

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