Thrombophilia work-up and clinical outcomes in Indian patients with unprovoked venous and arterial thrombosis aged 18-50 years

Harimadhavan, Monisha; Ram, Bharath; G, Karthick R; Shetty, Devi Prasad; Prabhu, Shilpa; S, Nataraj K; Nayak, Akshatha; Damodar, Sharat; Zanon, Ezio; Castaman, Giancarlo; Federici, Augusto Bramante; Mancuso, Maria Elisa; Pasut, Gianfranco; Tosetto, Alberto; Rocino, Angiola; Santoro, Rita Carlotta; Barcellona, Doris; Tripodi, Armando; Di Castelnuovo, Augusto; Persichillo, Mariarosaria; Candura, Fabio; Marchesini, Emanuela; Forni, Gian Luca; Gringeri, Alessandro; Gentilini, Ilaria; Tricoli, Mirko; Najjar, Osama; Teofili, Luciana

doi:10.4081/btvb..193

Editorials

In this issue

Giovanni de Gaetano, Chiara Cerletti

https://doi.org/10.4081/btvb.2026.588

386

PDF: 72
- PDF
In memoriam of Prof. Armando D’Angelo (1952-2024)

Franco Piovella, Björn Dahlbäck, Raimondo De Cristofaro, Jim Morrissey, Bruce L. Davidson, Stefanie Mahan, Hugo ten Cate, Alex Spyropoulos, Charles Mahan, Charles T. Esmon, Valerio De Stefano, Francesco Bernardi

https://doi.org/10.4081/btvb.2026.589

429

PDF: 102
- PDF

Reviews

Expanding the genetic landscape of hereditary thrombophilia: classical defects, novel variants, and genomic perspectives. A narrative review

Chiara Simion, Elena Campello, Walter Ageno, Paolo Simioni

https://doi.org/10.4081/btvb.2026.427

229

PDF: 45

SUPPLEMENTARY FILES: 27
- PDF
- SUPPLEMENTARY FILES
The expanded universe of thrombin: a comprehensive review of its hemostasis-independent roles and structure-function relationships

Monica Sacco, Stefano Lancellotti, Antonietta Ferretti, Maria Basso, Leonardo Di Gennaro, Raimondo De Cristofaro

https://doi.org/10.4081/btvb.2026.462

72

PDF: 31
- PDF
Lupus anticoagulant: a never-ending story. New insights from anti-prothrombin antibodies

Vittorio Pengo

https://doi.org/10.4081/btvb.2026.469

66

PDF: 36
- PDF
Perioperative management of patients taking direct oral anticoagulants: challenges in high-bleed-risk surgery and neuraxial anesthesia

Maria P. Ntalouka, Eleni M. Arnaoutoglou, James D. Douketis

https://doi.org/10.4081/btvb.2026.471

89

PDF: 41
- PDF
Inflammation and hemostatic system: a selection of involved clinical disorders

Francesco Marongiu, Antonella Mameli, Silvia Marongiu, Doris Barcellona

https://doi.org/10.4081/btvb.2026.474

63

PDF: 38
- PDF

Original Articles

Development and implementation of a mathematical model for inpatient warfarin dosing: rationale and methods

Nikolaos Tsaftaridis, Mark Goldin, Kanta Ochani, Todd Levy, Theodoros P. Zanos, Alex C. Spyropoulos

https://doi.org/10.4081/btvb.2026.195

215

PDF: 42
- PDF
Whole exome sequencing in a family with thromboangiitis obliterans

Barbara Lunghi, Dario Balestra, Nicole Ziliotto, Giulia Pavani, Matteo Bovolenta, Patrizia Della Valle, Mirko Pinotti, Giovanna Marchetti, Armando D'Angelo, Francesco Bernardi

https://doi.org/10.4081/btvb.2026.367

223

PDF: 35

SUPPLEMENTARY FILES: 22
- PDF
- SUPPLEMENTARY FILES
Clinical characteristics, prescription patterns and clinical outcomes of patients with extended therapy with direct oral anticoagulants for unprovoked venous thromboembolism Insights from the RIETE Registry

Alicia Lorenzo, Carmine Siniscalchi, Silvia Natalia Morales, Teresa Sancho, Reina Valle, Aida Gil-Diaz, Parham Sadeghipour, Patricia Sigüenza, Manuel Monreal, the RIETE Investigators

https://doi.org/10.4081/btvb.2026.403

366

PDF: 46

SUPPLEMENTARY FILES: 24

APPENDIX: 31
The LIKT sequence in C-terminus of tissue factor pathway inhibitor (TFPIα) crucially important for the synergistic TFPIα-cofactor activity of protein S and FV-short

Björn Dahlbäck, Sinh Tran, Piotr Draczkowski

https://doi.org/10.4081/btvb.2026.414

371

PDF: 34
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Impact of CYP2C19 loss-of-function variants on outcomes in atrial fibrillation patients undergoing percutaneous coronary intervention: rationale and study design of the WOEST-3 genetic substudy

Simona Chiusolo, Ashley Verburg, Carmela Morizzo, Ron H.N. Van Schaik, Maja Matic, Marieke J.H. Coenen, Michael Maeng, Jurrien ten Berg, Raffaele De Caterina

https://doi.org/10.4081/btvb.2026.421

267

PDF: 27

APPENDIX: 17
- PDF
- APPENDIX
Trypsin is as procoagulant as factor XIIa

Stephanie A. Smith, James H. Morrissey

https://doi.org/10.4081/btvb.2026.564

368

PDF: 45
- PDF

Case Reports

A case of inadvertent overdose with argatroban in a 13-month-old toddler in the cardiac catheterization lab setting

Charles E. Mahan

https://doi.org/10.4081/btvb.2026.567

74

PDF: 31
- PDF

Commentaries

Defending tranexamic acid and sensible scientific clinical trial design

Bruce L. Davidson

https://doi.org/10.4081/btvb.2026.405

60

PDF: 44
- PDF

Current Issue

Vol. 5 No. 3 (2026): In memory of Armando D’Angelo

Editorials

In this issue

In memoriam of Prof. Armando D’Angelo (1952-2024)

Reviews

Expanding the genetic landscape of hereditary thrombophilia: classical defects, novel variants, and genomic perspectives. A narrative review

The expanded universe of thrombin: a comprehensive review of its hemostasis-independent roles and structure-function relationships

Lupus anticoagulant: a never-ending story. New insights from anti-prothrombin antibodies

Perioperative management of patients taking direct oral anticoagulants: challenges in high-bleed-risk surgery and neuraxial anesthesia

Inflammation and hemostatic system: a selection of involved clinical disorders

Original Articles

Development and implementation of a mathematical model for inpatient warfarin dosing: rationale and methods

Whole exome sequencing in a family with thromboangiitis obliterans

Clinical characteristics, prescription patterns and clinical outcomes of patients with extended therapy with direct oral anticoagulants for unprovoked venous thromboembolism Insights from the RIETE Registry

The LIKT sequence in C-terminus of tissue factor pathway inhibitor (TFPIα) crucially important for the synergistic TFPIα-cofactor activity of protein S and FV-short

Impact of CYP2C19 loss-of-function variants on outcomes in atrial fibrillation patients undergoing percutaneous coronary intervention: rationale and study design of the WOEST-3 genetic substudy

Trypsin is as procoagulant as factor XIIa

Case Reports

A case of inadvertent overdose with argatroban in a 13-month-old toddler in the cardiac catheterization lab setting

Commentaries

Defending tranexamic acid and sensible scientific clinical trial design

authors

reviewers

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Keywords