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  A commitment to global collaboration, welcoming international participation and advancing science for the benefit of patients

  Pantep Angchaisuksiri, Wolfram Ruf, Jeffrey Weitz, Sam Schulman, Guy A. Young

  01-07-2025

  https://doi.org/10.4081/btvb.2025.188

  1069

  PDF: 149

  HTML: 0

• 29th National Conference of the Italian Society for the Study of Hemostasis and Thrombosis, 2025

  Guest Editor: Valerio De Stefano, Course President

  22-10-2025

  https://doi.org/10.4081/btvb.2025.408

  77
• 

  The key to fibrinolysis and thrombolysis

  Roger Lijnen, Désiré Collen

  09-09-2025

  https://doi.org/10.4081/btvb.2025.368

  286

  PDF: 70

  HTML: 42
• 

  Welcome to the 12th International Conference on Thrombosis and Hemostasis Issues in Cancer! Oral Communications and Posters

  Anna Falanga, Benjamin Brenner, Alok A. Khorana

  16-05-2024

  https://doi.org/10.4081/btvb.2024.139

  510

  PDF: 469
• 

  Science and scientists under attack

  Valerio De Stefano

  23-05-2023

  https://doi.org/10.4081/btvb.2023.80

  383

  PDF: 184

• PO54 | Resolvin response in bronchial asthma patients: endotype and clinical severity R. Liani¹, I. Altomare², P.G.M. Simeone¹, M. Alfonsetti¹, M. Mucci³, D. Madonna¹, S. Lattanzio¹, A. Ricci⁴, A.M. Draicchio², A. De Sanctis², P. Di Mattia², F. Papa², E. Cavallucci², F. Cipollone¹, A. Recchiuti³, F. Santilli¹ | ¹Department of Medicine and Aging, and Center for Advanced Studies and Technology “CAST”, G. d’Annunzio University of Chieti-Pescara, Chieti; ²Allergy and Immunology Section, Department Internal Medicine, G. d’Annunzio University, School of Medicine, Chieti; ³Department of Medical, Oral and Biotechnological Sciences, and Center for Advanced Studies and Technology “CAST”, G. d’Annunzio University, Chieti-Pescara; ⁴Department of Pharmacy, University G. d’Annunzio of Chieti Pescara, Chieti, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.323

  67
• 

  Well begun is half done

  Giovanni de Gaetano

  14-12-2022

  https://doi.org/10.4081/btvb.2022.61

  1571

  PDF: 185

• CO01 | Statin therapy for the prevention of venous thromboembolism in cancer patients: a systematic review and meta-analysis F. Catalani, R. Del Giorno, R. Canevascini, W. Ageno, L. Gabutti, G. Prouse, L. Giovannacci | Ospedale Regionale di Bellinzona, Switzerland.

  22-10-2025

  https://doi.org/10.4081/btvb.2025.199

  89

• PO84 | Beyond the scores: unmasking a silent pulmonary embolism in essential thrombocythemia N. Battino | ASL Sulcis Iglesiente PO CTO, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.353

  68

• PO18 | Does muscle mass matter? Appendicular lean mass as a determinant of anti-XA activity in elderly patientes B.M. Zanforlini¹, V. Bernardi¹, E. Campello², E.M. Bicego¹, C. Curreri¹, A. Vaticano¹, C. Sartori¹, L. Manfron¹, A. Perencin¹, P. Rollo¹, A. Baruffol¹, L. Ruoso¹, C. Simion², C. Bulato², P. Berto², P. Simioni², G. Sergi¹ | ¹Department of Medicine, Geriatrics Section, University of Padova; ²Haemorrhagic and Thrombotic Diseases Unit, Department of Medicine DIMED, Padova University Hospital, Padova, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.278

  69

• CO42 | Oxidative stress may contribute to enhanced thrombopoiesis through miR-150: implications for aspirin response R. Liani¹, P.G.M. Simeone¹, M. Alfonsetti¹, M. Frezza¹, R. Tripaldi¹, S. Ciotti¹, M. Luongo², F. Cipollone¹, L. Vanella³, F. Santilli¹ | ¹Department of Medicine and Aging, and Center for Advanced Studies and Technology “CAST”, G. d’Annunzio University of Chieti-Pescara, Chieti; ²Immunotransfusion Service, Clinical Haematology of Chieti University Hospital, Chieti; ³Department of Drug Sciences, University of Catania, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.248

  66

• PO49 | Use of emicizumab in two patients with acquired hemophilia A: a new therapeutic approach S. Sorella, J. Micozzi, E. Baldacci, M. Biglietto, R. Mormile, A. Chistolini, R. Ciciani, L. Torrieri, N. Zhdanovskaya, M. Lorenzon, A. Delli Paoli, S. Ligia, C. Santoro | Hematology, Department of Translational and Precision Medicine, Policlinico Umberto I, Sapienza University of Roma, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.318

  70

• CO19 | Hypercoagulability in wild-type transthyretin amyloidosis: evidence from whole blood thromboelastometry A. Napolitano¹, L. Spiezia¹, C. Samà¹, A. Benetti¹, G. Sinigiani², L. De Michieli², A. Cipriani², P. Simioni¹ | ¹First Chair of Internal Medicine, Department of Medicine, University Hospital of Padua; ²Department of Cardiothoracic and Vascular Sciences & Public Health, University Hospital of Padua, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.223

  80
• 

  Still unmet problems with low molecular weight heparin prophylaxis of venous thromboembolism. An Italian survey

  Stefania Cavazza, Gualtiero Palareti*

  03-10-2025

  https://doi.org/10.4081/btvb.2025.177

  77

  PDF: 22

  HTML: 0

  XML: 0

  Supplementary: 3

• PO32 | Effect of the sodium-glucose co-transporter-2 (SGLT2) inhibitors on platelet activation and lipid peroxidation: results of a pilot study P.G.M. Simeone¹, R. Liani¹, M. Alfonsetti¹, B. Cancelli¹, M. Frezza¹, G. Raggiunti¹, S. Zeeba², F. Cipollone¹, G. Renda², F. Santilli¹ | ¹Department of Medicine and Aging Sciences, Center for Advanced Studies and Technology, University of Chieti; ²Department of Neuroscience, Imaging and Clinical Sciences, G. D’Annunzio University of Chieti-Pescara; ³University Cardiology Division, Heart Department, Policlinico SS Annunziata, Chieti, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.293

  66

• PO68 | Whole blood hypercoagulable profiles in a patient with markedly elevated lipoprotein(A) plasma levels and thrombotic complications: a case report C. Portinari, M. Biolo, A. Napolitano, L. Spiezia, A. Colpo, S. Zambon, A. Zambon, P. Simioni | Department of Medicine, Padova University Hospital, Padova, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.337

  70

• CO50 | Diagnostic accuracy of the heparin-induced multiple electrode aggregometry (HIMEA) functional test for heparin-induced thrombocytopenia M. Bovara¹, M. Sebastiani², Am. Gori^3,4, A. Rogolino^3,4, A. Bertelli^3,4, G. Ciarrocca Taranta^3,4, R. Marcucci^3,4, M. Sartori⁵, B. Cosmi⁵, M. Silingardi⁶, A. M. Pizzini⁶, A. Marrocchi¹, R. Mancini¹ | ¹Laboratorio Unico Metropolitano Ospedale Maggiore, AUSL Bologna; ²IRCCS Istituto delle Scienze Neurologiche, Bologna; ³Centro Malattie Aterotrombotiche Azienda Ospedaliera Universitaria Careggi, Firenze; ⁴Dipartimento di Medicina Sperimentale e Clinica, Università di Firenze; ⁵U.O. di Angiologia e Malattie della Coagulazione dell’Azienda Ospedaliero Universitaria Policlinico S. Orsola-Malpighi, Bologna; ⁶Medicina Interna Ospedale Maggiore, Bologna, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.260

  66

• CO30 | Joint prosthetic surgery in patients with hemophilia A: clinical-functional outcomes and quality of life E. Zanon¹, A. Napolitano¹, A. Berizzi², P. Simioni¹ | ¹Haemophilia Center, First Chair of Internal Medicine, Department of Medicine, University-Hospital of Padua Medical School, Padua; ²Orthopedics and Traumatology Unit, University-Hospital of Padua Medical School, Padua, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.236

  76

• PO40 | Management of paediatric patients affected by mild factor VII deficiency undergoing surgery B. Borsellino^1,2, B. Pollio¹, I. Ricca¹, R. Albiani¹, T. Martini¹ | ¹Haemophilia Centre, Immune-Haematology and Transfusion Medicine, University Hospital “Città della Salute e della Scienza”, Turin; ²Department of Biomedicine and Prevention, PhD in Immunology, Molecular Medicine and Applied Biotechnology, University of Roma Tor Vergata, Roma, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.303

  67

• PO82 | Retrospective application of the TH2 score in a multicenter cohort of ITP patients: a reliable predictive tool or a score in need of refinement? C. Giubbilei¹, M. Defina², S. Rosati³, M. Rocco³, A. Votto⁴, F. Simonetti⁵, F. Paoletti⁶, V. Carrai¹ | ¹Hematology Unit, AOU Careggi; ²Hematology unit AOU Senese; ³Hematology Unit Azienda Sanitaria Toscana Centro; ⁴Hematology Unit, AOU Pisana; ⁵Hematology Unit, Ospedale Versilia; ⁶Hematology Unit, Azienda Sanitaria Nord Ovest, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.351

  77

• PO16 | Antithrombotic treatment and outcomes in retinal vein occlusion: a retrospective cohort study and comparison with historical group S.A. Malerba^1,2, M.T. Sartori¹, G. Libralon¹, C. Dalla Porta¹, P. Simioni¹ | ¹First Medical Clinic, Department of medicine- DIMED, Università degli Studi di Padova; ²Medicina Generale, Ospedale dell’Angelo, Mestre, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.277

  67

• CO39 | Artificial intelligence in hemophilia management: challenging the need for experts G. Sottilotta¹, D. Megalizzi¹, F. Luise² | ¹UOSD Microcitemie - Emostasi e Trombosi. Grande Ospedale Metropolitano Bianchi-Melacrino-Morelli, Reggio Calabria; ²Laboratorio Analisi, Grande Ospedale Metropolitano Bianchi-Melacrino-Morelli, Reggio Calabria, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.246

  67

• PO48 | Thrombotic risk evaluation and thrombophilia testing in β-thalassemia patients: a retrospective cohort analysis from a reference regional center G.M. Camarda^1,2*, S. Raso^1*, R. Di Maggio¹, M. Vinciguerra³, A. Giangreco¹, A. Inzerillo¹, A. Maggio, M. Napolitano^1,2 | ^*These authors contributed equally to this abstract; ¹Hematology and Rare Diseases Unit, Azienda Ospedaliera Ospedali Riuniti Villa Sofia-Cervello, Palermo; ²Division of Hematology Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties “ProMISE”, Palermo; ³UOSD Molecular Diagnosis of Rare Blood Diseases, Azienda Ospedaliera, Ospedali Riuniti Villa Sofia, Cervello, Palermo, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.317

  61

• CO17 | Clinical relevance of isolated anti-phosphatidylserine/ prothrombin antibody positivity A. Hoxha¹, P. Žigon^2,3, L. Katja^2,3, S. Čučnik^2,4, Ž. Rotar^2,5, S. Gavasso¹, P. Zerbinati¹, G. Gobbo¹, P. Simioni¹ | ¹University of Padua, Internal Medicine Unit, Thrombotic and Hemorrhagic Centre, Department of Medicine-DIMED, Padua, Italy; ²University Medical Centre Ljubljana, Department of Rheumatology, Ljubljana, Slovenia; ³University of Primorska, Faculty of Mathematics, Natural Sciences and Information Technologies, Koper, Slovenia; ⁴University of Ljubljana, Faculty of Pharmacy, Ljubljana, Slovenia; ⁵University of Ljubljana, Faculty of Medicine, Ljubljana, Slovenia

  22-10-2025

  https://doi.org/10.4081/btvb.2025.221

  84

• PO31 | Comparative analysis of anticoagulant therapy in patients over 90 years old: vitamin K antagonists versus direct oral anticoagulants G. Sottilotta¹, P. Arrigo², S. Cuzzocrea¹, D. Megalizzi¹, F. Luise³ | ¹UOSD Microcitemie, Emostasi e Trombosi, Grande Ospedale Metropolitano di Reggio Calabria; ²Associazione Italiana Pazienti Anticoagulati, Sezione di Reggio Calabria; ³Laboratorio Analisi. Grande Ospedale Metropolitano di Reggio Calabria, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.292

  60

• PO66 | Viscoelastic tests in disseminated intravascular coagulation associated with aortic aneurysm A. M. Pizzini¹, C. Biasoli², M. Bovara³, E. Gesuete¹, A. Fusco¹, C. Fantoni¹, P. Pedrazzi², R. Mancini³, M. Silingardi¹ | ¹Ambulatorio Emostasi & Trombosi, Dipartimento Medico, Ospedale Maggiore AUSL Bologna; ²SSI Presa in Carico delle Malattie Emorragiche e Tromboemboliche della Romagna; ³Laboratorio Unico Metropolitano AUSL Bologna, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.335

  62

• CO49 | The burden of cerebral small vessel disease in ITTP patients from acute phase to remission A. Truma^1,2, F. M. Lo Russo¹, G. Conte^1,2, I. Mancini¹, M. Abbattista¹, J. A. Giannotta¹, A. Artoni¹, B. Ferrari¹, P. Agosti^1,2, F. M. Triulzi^1,2, F. Peyvandi^1,2 | ¹Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Milan; ²Università degli Studi di Milano, Department of Pathophysiology and Transplantation, Milan, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.259

  65

• CO27 | Intracerebral hemorrhage in hemophilia A and B: a 10-year prospective multicenter study in Italy (2012–2022) E. Zanon¹, A. Napolitano¹, A. Porreca², F. Demartis³, A. Coppola⁴, C. Santoro⁵, I. Cantori⁶, A. C. Molinari⁷, C. Biasioli⁸, M. Luciani⁹, G. Sottilotta¹⁰, B. Pollio¹¹, A. Borchiellini¹², A. Tosetto¹³, P. Flora¹⁴, P. Simioni¹ | ¹Haemophilia Center, First Chair of Internal Medicine, Department of Medicine, University-Hospital of Padua Medical School, Padua; ²Department of Human Sciences and Promotion of the Quality of Life, Unit of Clinical and Molecular Epidemiology IRCCS San Raffaele Roma Open University, Roma; Unit of Clinical and Molecular Epidemiology IRCCS San Raffaele, Roma; ³Centre for Bleeding Disorders, Careggi University Hospital of Firenze; ⁴Azienda Ospedaliero Universitaria di Parma; ⁵Hematology Division, Umberto I University Hospital of Roma; ⁶Haemophilia Center, Department of Transfusion Medicine, Hospital of Macerata; ⁷IRCCS Istituto Giannina Gaslini, Genova; ⁸Haemophilia and Transfusion Centre, Bufalini Hospital, Cesena; ⁹Children’s Hospital Bambino Gesù, Roma; ¹⁰Haemophilia Center, Department of Onco-Hematology and Radioterapy, Hospital of Reggio Calabria; ¹¹Haemophilia Pediatric Center, Transfusion Medicine, City of Health and Science of Turin; ¹²City of Health and Science of Turin; ¹³Hemorrhagic and Thrombotic Diseases Unit, S. Bortolo Hospital of Vicenza; ¹⁴RCCS Foundation Ca’ Granda Maggiore Policlinico Hospital, Milan, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.233

  72

• PO38 | Rates of hemorrhagic events and hemodialysis circuit thrombosis in patients with end-stage renal disease on hemodialytic treatment receiving a factor-XI inhibitor: a systematic review and meta-analysis D. Santagata, G. Barbui, M.P. Donadini, A. Squizzato | Department of Medicine and Surgery, Research Center on Thromboembolic Disorders and Antithrombotic Therapies, University of Insubria, Varese and Como, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.301

  60
• 

  At the age of three

  Giovanni de Gaetano, Chiara Cerletti

  16-12-2024

  https://doi.org/10.4081/btvb.2024.166

  366

  PDF: 92

• PO81 | Direct oral anticoagulants in atypical site vein thrombosis: a single centre experience focused on cancer patients U. Mazzarelli¹, A. Guida¹, L. Agrelli¹, M. Amato¹, R. Guarrasi², L. Santaniello², C. Cardamone¹, P. Vitale¹, M. Triggiani¹ | ¹Centro per le Malattie Emorragiche Congenite e Malattie Trombotiche UOC Clinica Immunologica e Reumatologica AOU S. Giovanni di Dio e Ruggi d’Aragona, Salerno; ²UOC Clinica Oncologica AOU S. Giovanni di Dio e Ruggi d’Aragona, Salerno, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.350

  75

• PO15 | Venous thromboembolism risk associated with midline catheters and peripherally inserted central catheters: a systematic review and meta-analysis D. Santagata¹, F. Subri¹, F. Dentali^1,2, M.P. Donadini¹, I. Giarretta² | ¹Department of Medicine and Surgery, Research Center on Thromboembolic Disorders and Antithrombotic Therapies, University of Insubria, Varese and Como; ²Department of Internal Medicine, Ospedale di Circolo and Fondazione Macchi, Varese, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.276

  73

• CO36 | Inhibitor titer at diagnosis and clinical course in acquired hemophilia A: a single-center experience C. Simion, B. Stocco, E. Dalla Porta, E. Campello, G. Furlan, L. Spiezia, G. Saggiorato, F. Sartorello, E. Zanon, P. Simioni | Department of Medicine – DIMED, University of Padua, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.243

  65

• PO47 | Hemophilia A and antithrombin deficiency: a case of natural hemostatic rebalancing L. Torrieri, S. Ligia, E. Baldacci, R. Mormile, S. Sorella, R. Ciciani, M. Biglietto, N. Zhdanovskaya, A. Delli Paoli, A. Tirnetta, M. Lorenzon, C. Santoro | Hematology, Department of Translational and Precision Medicine, Policlinico Umberto I, Sapienza University of Roma, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.316

  76

• CO15 | Longitudinal coagulation profiling of individuals undergoing gender-affirming hormone therapy: the hyper-gender study A. Napolitano, E. Campello, A. Scala, C. Simion, C. Bulato, S. Gavasso, C. Samà, A. Benetti, S. Toffanin, G. Faggian, R. Scafa, A. Garolla, P. Simioni | First Chair of Internal Medicine, Department of Medicine, University Hospital of Padua; Unit of Andrology and Reproductive Medicine, Department of Medicine, University Hospital of Padua, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.219

  72

• PO25 | Baseline thrombin generation test does not predict thrombotic events in acute leukemia: a monocentric prospective study M. Biglietto, R. Mormile, M.L. Bisegna, A. Laganà, A. L. Faccini, A. Papa, E. Baldacci, C. Santoro, M.S. De Propris, A. Chistolini | Hematology, Department of Translational and Precision Medicine Sapienza University of Roma, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.286

  63

• PO65 | Utilization of emicizumab in acquired hemophilia A: a case report C. Caputo, P. Conca, I.L. Calcaterra, E. Cimino, M. Romeo, M. Aversano, E. Franco, C. De Luca, G. D’errico, L. Jr Valletta, M. Di Minno, A. Tufano | Department of Clinical Medicine and Surgery, Federico II University, Naples, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.334

  62

• CO47 | Genetic characterization of the KIV2 LPA polymorphism in subjects with bicuspid aortic valve with different clinical complications R. Orsi¹, G. Barbieri¹, E. Sticchi^1,2, A. Kura¹, L. Squillantini¹, P. Cantini¹, A. Rogolino², M. Berteotti^1,2, S. Nistri³, P. Stefàno⁴, R. Marcucci^1,2, B. Giusti^1,2 | ¹Department of Experimental and Clinical Medicine, University of Firenze; ²Centre for Atherothrombotic Diseases, AOU Careggi, Firenze; ³Cardiology, CMSR Veneto Medica, Altavilla Vicentina; ⁴Cardiac Surgery, AOU-Careggi, Firenze, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.257

  61

• CO24 | Extracellular vesicles profiles in patients with wild-type transthyretin amyloidosis S. Toffanin¹, L. Spiezia¹, C.M. Radu¹, A. Napolitano¹, A. Benetti¹, C. Samà¹, E. Campello¹, L. De Michieli², G. Sinigiani², A. Cipriani², P. Simioni¹ | ¹First Chair of Internal Medicine, Department of Medicine, University-Hospital of Padua Medical School, Padua; ²Department of Cardiac, Thoracic and Vascular Sciences and Public Health, University of Padua, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.230

  65

• PO37 | Single centre experience on anticoagulation in carriers of non-mild inherited thrombophilia: direct oral anticoagulants (DOAC) efficacy and safety M. D’uva^1,2, G. La Barba¹, G. Montanaro¹, M. Di Ianni^1,2, P. Ranalli^1,2 | ¹Hematology Unit, S. Spirito Hospital, Pescara; ²Department of Medicine and Aging Sciences, D’Annunzio University, Chieti, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.300

  67

• PO80 | Heparin-induced thrombocytopenia: a monocentric experience with danaparoid L. D’Innocenzo, S. Sorrentino, M. De Siati, A. Ferretti, E. De Candia | Unit of Haemostasis and Thrombosis Diseases, Fondazione Policlinico Universitario A. Gemelli, IRCCS, Roma, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.349

  71

• PO09 | Comparison of different aggregometry methods for evaluation of platelet function in patients with myeloproliferative neoplasms C. Fortino, I. Bertozzi, D. Regazzo, L. Gianesello, G. Nuozzi, F. Sartorello, V. Azzaro, G. Saggiorato, A. Bertomoro, P. Simioni | First Medical Clinic, Department of Medicine – DIMED, Università degli Studi di Padova, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.271

  65

• CO35 | Bleeding phenotype characterization in patients with congenital bleeding disorders: a multigenic approach using next generation sequencing to identify coagulation-modulating variants C. Simion, L. Gianesello, C. Bulato, A. Benetti, E. Campello, A. Giannella, G. Ceolotto, E. Zanon, L. Spiezia, P. Simioni | Department of Medicine – DIMED, University of Padua, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.242

  67

• PO02 | Pregnancy and delivery in women with hemophilia and carriers are still challenging: a ten years analysis from The Italian Association of Hemophilia Centers (AICE) M. Napolitano¹, M. Mattana², C. Cammarata¹, M. Leotta³, S. Linari⁴, M.E. Mancuso⁵, G. F. Rivolta⁶, C. Santoro⁷, L. Valdrè⁸, R.C. Santoro³, S. Siragusa¹ | ¹Department of Health Promotion, Mother and Child Care, Internal Medicine and Med, Palermo; University of Palermo, Italy; ²Department of Precision Medicine in Medical, Surgical and Critical Care “Me. Pre. Cc”, University of Palermo; ³Hemostasis and Thrombosis Unit, Azienda Ospedaliera Universitaria Dulbecco, Catanzaro; ⁴Center for Bleeding Disorders, Careggi University Hospital, Firenze; ⁵Center for Thrombosis and Hemorrhagic Diseases, IRCCS Humanitas Research Hospital, Rozzano, Milan; ⁶Regional Reference Center for the Treatment of Congenital Hemorrhagic Diseases, Parma University Hospital, Parma; ⁷Hematology, University Hospital Policlinico Umberto I, Roma; ⁸Inherited Bleeding Disorders Unit, IRCCS AOUBO, Bologna, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.312

  66

• CO12 | Left internal carotid artery thrombosis in a patient with antiphospholipid antibody syndrome successfully treated with eculizumab A. Hoxha¹, L. Nico², F. Viaro³, L. Fabris¹, Y.F. Herrera¹, M. Munari⁴, C. Baracchini³, F. Causin², P. Simioni¹ | ¹Internal Medicine Unit, Thrombotic and Haemorrhagic Centre, Department of Medicine - DIMED, University of Padua; ²Neuradiology Unit, University Hospital of Padua; ³Stroke Unit, Neurology Department, University of Padua; ⁴Intensive Care Unit, University Hospital of Padua, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.216

  80

• PO89 | Apixaban for secondary prevention of venous thromboembolism in hemodialysis patients: pharmacokinetic profile and safety outcomes S. Guglielmo¹, E. De Bon², L. Scarano¹, R. Fabris¹, E. Pierobon³, S. Barbar² | ¹Internal Medicine, Department of Medicine; ²Thrombotic and Hemorrhagic Disorders Unit, Department of Medicine; ³Nephrology and Dialysis Unit, Azienda ULSS 6 Euganea, Cittadella and Camposampiero, Padua, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.359

  87

• PO24 | Emicizumab prophylaxis and bleeding outcomes: a single center clinical experience A. Taglietti¹, S. Ligia¹, F. Paoletti¹, R. Mormile¹, E. Baldacci², A. Chistolini¹, C. Santoro^1,2 | ¹Hematology, Department of Translational and Precision Medicine, Sapienza University of Roma; ²Hematology, Azienda Ospedaliera Universitaria Policlinico Umberto I, Roma, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.285

  62

• PO64 | A silent hemorrhage in the immuno-thrombotic chaos of antiphospholipid syndrome G. Autiero, S.A. Malerba, A. Malaguti, M. Dalla Vestra, F. Presotto | Medicina Generale, Ospedale dell’Angelo, Mestre-Venezia, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.333

  66

• CO46 | Comparison of reticulated platelet procoagulant role in liver cirrhosis vs. fibrosis S. Toffanin¹, E. Campello¹, A. Zanetto², G. Gagliardi¹, A. Napolitano¹, E. Stocco¹, G. Gobbo¹, E. Pinto², C. M. Radu¹, M. Senzolo², L. Fabris¹, P. Simioni¹ | ¹First Chair of Internal Medicine, Department of Medicine, University-Hospital of Padua Medical School, Padova; ²Department of Surgery Oncology and Gastroenterology, Gastroenterology and Multivisceral Transplant Unit, Padova University Hospital, Padova, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.256

  71

• CO23 | Markers of inflammation and hypofibrinolysis are associated with cognitive dysfunction and motor performances in atrial fibrillation patients on oral anticoagulant therapy: insights from the Strat-AF study F. Alfano^1,2, F. Cesari^1,2, A.M. Gori^1,2, M. Berteotti^1,2, E. Salvadori³, B. Giusti^1,2, A. Bertelli^1,2, F. Fratini⁴, A. Rogolino^1,2, B. Formelli^4,5, F. Pescini^4,5, E. Fainardi⁶, E. Barucci⁴, G. Salti⁵, A. Cavaliere⁴, A. Ginestroni⁶, A. Poggesi^4,5, R. Marcucci^1,2 | ¹Department of Experimental and Clinical Medicine, University of Firenze; ²Center for Atherothrombotic Diseases, Careggi University Hospital, Firenze; ³Department of Biomedical and Clinical Sciences, University of Milan; ⁴NEUROFARBA Department, Neuroscience Section, University of Firenze; ⁵Stroke Unit, Careggi University Hospital, Firenze; ⁶Neuroradiology Unit, Careggi University Hospital, Department of Experimental and Clinical Biomedical Sciences, University of Firenze, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.229

  73

• PO35 | Cerebral veins thrombosis in patients with and without myeloproliferative neoplasm: a real life retrospective monocentric study I. Bertozzi, M.T. Sartori, M. Zerbinati, G. Libralon, A. Galbiati, P. Simioni | First Medical Clinic, Department of Medicine - DIMED, Università degli Studi di Padova, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.298

  64
• 

  Welcome to AICE and sincere wishes for peace for the new year 2024

  Giovanni de Gaetano

  27-12-2023

  https://doi.org/10.4081/btvb.2023.107

  1296

  PDF: 154

• PO79 | Trying to hit the hit in the shadow of renal failure: a complex case managed with danaparoid S. Chessa^1,2, M. Anedda², M.V. Cherchi², M. Vacca^1,2, M. Caboni², J. Pilia², A.M. Bussu², M. Mantega², G. Costanzo¹, D. Firinu¹, S. Del Giacco¹, A. Mameli³, D. Barcellona³ | ¹Department of Medical Science and Public Health, University of Cagliari; ²Internal Medicine, ASL Sulcis, PO Sirai, Carbonia; ³Department of Medical Sciences and Public Health, Hemostasis and Thrombosis Unit, University of Cagliari and AOU of Cagliari, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.348

  75

• PO06 | Extracellular vesicles profiles in patients with porto-sinusoidal vascular disease S. Toffanin¹, E. Campello¹, A. Zanetto², C. M. Radu¹, E. Pinto², K. Fernande², C. Bulato¹, B. Serena¹, L. Spiezia¹, P. Burra², M. Senzolo², P. Simioni¹ | ¹First Chair of Internal Medicine, Department of Medicine, University Hospital of Padua Medical School, Padua; ²Department of Surgery Oncology and Gastroenterology, Gastroenterology and Multivisceral Transplant Unit, University Hospital of Padua, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.268

  70

• CO34 | Evaluation of emicizumab concentration and thrombin generation in a cohort of severe hemophilia A patients with and without inhibitor A. Taglietti¹, S. Ligia¹, F. Paoletti¹, R. Mormile¹, E. Baldacci², A. Chistolini¹, C. Santoro^1,2 | ¹Hematology, Department of Translational and Precision Medicine, Sapienza University of Roma; ²Hematology, Azienda Ospedaliera Universitaria Policlinico Umberto I, Roma, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.241

  66

• PO01 | Diagnosis of inherited platelet function disorders by platelet aggregometry using a fully automated coagulation analyzer E. Falcinelli¹, A.M. Mezzasoma¹, L. Bury¹, R. Martini¹, I. Tano¹, A. Rechner², P. Gresele¹ | ¹Department of Medicine, Section of Internal and Cardiovascular Medicine, University of Perugia, Italy; ²Sysmex Europe, Germany

  22-10-2025

  https://doi.org/10.4081/btvb.2025.311

  65

• CO03 | Early discharge and home treatment of low-risk pulmonary embolism: a cohort study E. Ruggeri¹, L. Vulcano¹, W. Ageno², F. Cortellaro³, M.P. Donadini^3,4 | ¹Scuola di Medicina, Università degli Studi dell’Insubria, Varese; ²Dipartimento di Medicina, Università degli Studi di Padova; ³Pronto Soccorso e Medicina d’Urgenza, Ospedale di Circolo, ASST Sette Laghi, Varese; ⁴Dipartimento di Medicina e Chirurgia, Università degli Studi dell’Insubria, Varese, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.208

  86

• PO88 | Bacterial lysate “lantigen B” induces proliferation of B and NK cells and the release of related cytokines M. Alfonsetti¹, R. Liani¹, P. Di Mattia³, M. Tredicine⁴, F. Papa³, Q. Niu⁵, M. Di Gioacchino², F. Santilli^1,3 | ¹Department of Medicine and Aging, Center for Advanced Studies and Technology, University of Chieti, Italy; ²Institute for Clinical Immunotherapy and Advanced Biological Treatments, Pescara, Italy; ³Specialization School of Allergy and Clinical Immunology, G. d’Annunzio University, Chieti, Italy; ⁴Department of Medical, Oral, and Biotechnology Science, University G. d’Annunzio, Chieti-Pescara, Chieti, Italy; ⁵Department of Occupational Health, School of Public Health, Shanxi Medical University, Taiyuan, Shanxi, China

  22-10-2025

  https://doi.org/10.4081/btvb.2025.358

  74

• PO21 | Exploring endothelial damage: the interplay between coagulopathy, capillary leak and vasoplegia in sepsis M. Facci¹, G. Turcato¹, A. Zaboli², L. Filippi¹, P. Ferretto¹, M. Maggi¹, F. Lucente¹, D. Milazzo¹, A. Bresolin¹, M. Marchetti¹ | ¹UOC Medicina Generale, Ospedale Alto Vicentino, Santorso, (VI); ²Innovation, Research and Teaching Service “SABES-ASDAA” of Azienda Sanitaria dell’Alto Adige, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.281

  58

• PO56 | Safety of anticoagulant treatment in patients with splanchnic vein thrombosis and history of portal hypertension-related bleeding R. Talerico¹, S. Pellegrino¹, A. Plessier², F.R. Ponziani³, A. Porfidia¹, F. Landi¹, A. Gasbarrini³, R. Pola¹, F. Santopaolo³ | ¹Department of Geriatric, Orthopedic, and Rheumatologic Sciences, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Roma, Italy; ²Université de Paris, AP-HP, C, DMU DIGEST, Centre de Référence des Maladies Vasculaires du Foie, FILFOIE, ERN RARE-LIVE. Centre de recherche sur l’inflammation, Inserm, Paris, France; ³Department of Medical and Surgical Sciences, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Roma, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.325

  69

• CO45 | Role of urinary 11-dehydro-thromboxane B2 as a predictor of preeclampsia in pregnant high-risk women on low-dose aspirin treatment P.G.M. Simeone¹, R. Liani¹, M. Alfonsetti¹, A. Ricci¹, V. Cianci¹, S. Zeeba², M. Molino³, S. Palma², R. Malizia⁴, M. Luongo⁴, A. Di Castelnuovo⁵, F. Cipollone¹, F. D’antonio⁶, F. Ricci², G. Renda², F. Santilli¹ | ¹Department of Medicine and Aging Sciences, Center for Advanced Studies and Technology, University of Chieti; ²Department of Neuroscience, Imaging and Clinical Sciences, G D’Annunzio University of Chieti-Pescara, Chieti; University Cardiology Division, Heart Department, Policlinico SS Annunziata, Chieti; ³Clinical Pathology of Chieti University Hospital; ⁴Immunotransfusion Service, Clinical Haematology of Chieti University Hospital, Chieti; ⁵Mediterranea Cardiocentro, Napoli; ⁶Centre for Fetal Care and High-Risk Pregnancy, Department of Obstetrics and Gynecology, University of Chieti, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.251

  70

• CO22 | Assessment of coagulation profiles in septic patients using viscoelastic coagulation monitoring and rotational thromboelastometry in an internal medicine setting G. Gottardi, C. Simion, D. Regazzo, C. Samà, G.P. Arcidiacono, L. Gianesello, E. Campello, P. Simioni | Department of Medicine – DIMED, University of Padua, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.228

  70

• PO34 | A negative oncologic follow up doesn’t always really mean no cancer: two case report of cancer-associated thrombotic microangiopathy E. Cosi, A. Bertomoro, G. Bogoni, I. Bertozzi, I. Cortella, P. Simioni | Clinica Medica ORI, Azienda Ospedale-Università Padova, DIDAS, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.297

  70

• PO70 | Clinical safety and monitoring of apixaban combined with tacrolimus and everolimus in kidney transplant patients: a prospective study S. Guglielmo¹, E. De Bon², L. Scarano¹, R. Fabris¹, E. Pierobon³, S. Barbar² | ¹Internal Medicine, Department of Medicine, Azienda ULSS 6 Euganea, Cittadella; ²Thrombotic and Hemorrhagic Disorders Unit, Department of Medicine, Azienda ULSS 6 Euganea, Cittadella; ³Nephrology and Dialysis Unit, Azienda ULSS 6 Euganea, Cittadella and Camposampiero, Padova, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.339

  57

• PO05 | Intensive FVIII replacement in haemophilia patients with hypertrophic synovium: a randomized study I.L. Calcaterra¹, E. Baldacci², R. Marino³, F. Valeri⁴, R.C. Santoro⁵, G. Pasta⁶, C. Martinoli⁷, M. Di Minno¹ | ¹Department of Clinical Medicine and Surgery, Federico II University, Naples; ²Haematology, University Hospital Policlinico Umberto I, Roma; ³Haemophilia Center and thrombosis, Policlinico, Bari; ⁴Regional Centre for Haemorrhagic and Thrombotic Diseases, AOU Città Della Salute e Della Scienza; Turin; ⁵Centre for Hemorrhagic and Thrombotic Disorders, Pugliese Ciaccio Hospital, Catanzaro; ⁶Fondazione IRCCS San Matteo Hospital, Pavia; ⁷Department of Health Science DISSAL, University of Genoa, Unit of Radiology and IRCCS San Martino Hospital, Genoa, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.267

  60

• CO33 | Acquired hemophilia A in Liguria, Italy: what six years of data reveal C. Vernarecci¹, A. C. Molinari¹, P. Ballarino², M. Caiti², E. Cenni², P. Moscatelli², L. Banov¹ | ¹IRCCS Istituto Giannina Gaslini, Genova; ²IRCCS Policlinico San Martino, Genova, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.240

  69

• CO41 | Failure in assisted reproductive techniques: insights from the first registry E. Grandone^1,3,4, C. Lodigiani², D. Colaizzo³, M. Passaretti², J. Khizroeva⁴, A. De Laurenzo³, P. Totaro⁵, E. Bucherini⁶, D. Baldini⁷, V. Bitsadze⁴, A. Makatsarya⁴, M. Mastroianno³, G. Piazza⁸, M. Othman⁹, M. Margaglione¹ | ¹University of Foggia, Italy; ²Humanitas University, Rozzano, Italy; ³IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy; ⁴First Sechenov University, Russia; ⁵Santa Maria Hospital, Bari, Italy; ⁶Angiologia, Faenza, Italy; ⁷Momo Fertilife, Bisceglie, Italy; ⁸Brigham Women Hospital, USA; ⁹Queen’s University, Kingston, Canada

  22-10-2025

  https://doi.org/10.4081/btvb.2025.310

  71

• CS03 | Khorana risk score and genomic profiling for prediction of venous thromboembolism in ovarian cancer P. Santini, F. Mancinetti, S.M.P. D’Ambrosio, M. Bigossi, A. D’Errico, E. Fondi, G. Fracassa, E. Ianuà, L. Mastrantoni, G. Anderson, F. Camarda, I. Marino, J. Preziosi, M. Buttarelli, M. Manfredelli, A. Minucci, F. Persiani, L. Giacò, T. Pasciuto, I. Conti, I. Mozzetta, C. Marchetti, V. Salutari, G. Scambia, C. Nero, R. Pola | Agostino Gemelli University Polyclinic Foundation IRCCS, Roma, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.200

  91

• PO86 | Emicizumab in patients with moderate hemophilia A and severe bleeding phenotype: single-center real-world experience A.L. Faccini, M. Biglietto, S. Sorella, E. Crisanti, M. Antonacci, R. Mormile, R. Ciciani, E. Baldacci, C. Santoro, S. Ligia | Hematology, Department of Translational and Precision Medicine Sapienza University of Roma, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.355

  91

• PO19 | Joint health status in patients with moderate hemophilia A: a cross-sectional multi-center study I.L. Calcaterra¹, F. Picasso², F. Valeri³, E. Baldacci⁴, M. Napolitano⁵, C. Guerrino¹, E. Zanon⁶, C. Santoro⁴, S. Siragusa⁷, C. Martinoli², M. Di Minno¹ | ¹Department of Clinical Medicine and Surgery, Regional Reference Centre for Coagulation Disorders, Federico II University, Naples; ²Department of Health Sciences “DISSAL”, Università di Genova; ³Regional Centre for Hemorrhagic and Thrombotic Diseases, AOU Città della Salute e della Scienza, Turin; ⁴Haematology, Department of Translational and Precision Medicine, Sapienza University, Roma; ⁵Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, University of Palermo and Haematology Unit and Rare Disorders Hospital “V. Cervello”, Palermo; ⁶Haemophilia Centre, General Medicine, Padua University Hospital, Padua; ⁷Department PROMISE, University of Palermo, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.279

  69

• CO43 | Early platelet dysfunction in sepsis: an ICU pilot study S. Sorrentino¹, C. Gori², L. D’Innocenzo¹, M. De Siati¹, Mg. Bocci³, E. De Candia¹ | ¹Unit of Haemostasis and Thrombosis Diseases, Fondazione Policlinico Universitario A. Gemelli, IRCCS, Roma; ²UOC Shock & Trauma, Azienda Ospedaliera San Camillo Forlanini, Roma; ³National Institute for Infectious Diseases, Lazzaro Spallanzani, IRCCS, Roma, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.249

  70

• CO21 | Viscoelastic testing in inherited bleeding disorders: a cross-sectional comparison between viscoelastic coagulation monitoring (VCM) and rotational thromboelastometry (ROTEM) C. Simion, C. Samà, C. Bulato, G. Gottardi, D. Regazzo, E. Campello, P. Simioni | Department of Medicine – DIMED, University of Padua, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.227

  71

• CS07 | Endothelial dysfunction and impaired angiogenesis in Hermansky-Pudlak syndrome (HPS) type 1: studies with endothelial colony forming cells F. Tondi¹, G. Purgatorio¹, C. Sgromo², E. Giglio¹, E. Petito¹, E. Falcinelli¹, G. Guglielmini¹, A. Follenzi², P. Gresele¹, L. Bury^1*, C. Olgasi^3* | ^*Shared senior authorship; ¹Department of Medicine and Surgery, Section of Internal and Cardiovascular Medicine, University of Perugia; ²Department of Health Sciences, School of Medicine, University of Piemonte Orientale, Novara; ³Department of Translational Medicine, School of Medicine, University of Piemonte Orientale, Novara, Italy

  16-09-2025

  https://doi.org/10.4081/btvb.2025.204

  70

• PO33 | Whole blood hypercoagulable profiles in patients with rheumatoid arthritis L. Spiezia¹, A. Giollo², C. Samà¹, A. Benetti¹, L. Di Luozzo², M. Salvato², A. Doria², P. Simioni¹ | ¹First Chair of Internal Medicine, Thrombotic and Hemorrhagic Diseases Unit, Department of Medicine, University Hospital of Padova; ²Rheumatology Unit, Department of Medicine, University Hospital of Padova, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.296

  66

• PO69 | Whole blood thrombin generation hypercoagulable profile in a patient with hemolytic crisis due to paroxysmal nocturnal hemoglobinuria: a case report A. Napolitano, L. Spiezia, C. Bulato, E. Campello, P. Simioni | First Chair of Internal Medicine, Department of Medicine, University-Hospital of Padua Medical School, Padua, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.338

  75

• CO51 | Novel biomarkers of neurological damage in acute immune-mediated thrombotic thrombocytopenic purpura A. Truma^1,2, I. Mancini¹, F. Verde^2,3, J. A. Giannotta¹, A. Artoni¹, B. Ferrari¹, P. Agosti^1,2, M. Gagliardi¹, A. Ratti^3,4, N. Ticozzi^2,3, F. Peyvandi^1,2 | ¹Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Milan; ²Università degli Studi di Milano, Department of Pathophysiology and Transplantation, Milan; ³Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan; ⁴Università degli Studi di Milano, Department of Medical Biotechnology and Translational Medicine, Milan, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.261

  49

• CO32 | Major surgery in patients with severe hemophilia A without inhibitors receiving prophylaxis with fitusiran E. Zanon, C. Simion, A. Napolitano, L. Spiezia, P. Simioni | Haemophilia Center, First Chair of Internal Medicine, Department of Medicine, University-Hospital of Padua Medical School, Padua, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.239

  70

• PO41 | Comparison of the haemorrhagic phenotype between female and male patients affected by autosomal inherited bleeding disorders in a single-centre cohort B. Borsellino^1,3, C. Zuccotti², L. Guarnera^3,4, C. Biasoli⁵, P. Pedrazzi⁵, T. Martini¹ | ¹Haemophilia Centre, Immune-Haematology and Transfusion Medicine, University Hospital “Città della Salute e della Scienza”, Turin, Italy; ²Department of Clinical Pathology, Bufalini Hospital, Cesena, Italy; ³Department of Biomedicine and Prevention, PhD in Immunology, Molecular Medicine and Applied Biotechnology, University of Roma Tor Vergata, Roma, Italy; ⁴Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH, USA; ⁵Haemophilia and Transfusion Centre, Bufalini Hospital, Cesena, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.304

  60