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  The landscape of rare coagulation factor deficiency management in Italy: a national hemophilia center survey

  Silvia Linari, Renato Marino, Marzia Leotta, Antonio Coppola, Patrizia Di Gregorio, Augusto Bramante Federici, Flora Peyvandi, Cristina Santoro, Ezio Zanon, Rita Carlotta Santoro

  05-11-2025

  https://doi.org/10.4081/btvb.2025.369

  1331

  PDF: 215

  HTML: 133

  Appendix: 119

• CO27 | Intracerebral hemorrhage in hemophilia A and B: a 10-year prospective multicenter study in Italy (2012–2022) E. Zanon¹, A. Napolitano¹, A. Porreca², F. Demartis³, A. Coppola⁴, C. Santoro⁵, I. Cantori⁶, A. C. Molinari⁷, C. Biasioli⁸, M. Luciani⁹, G. Sottilotta¹⁰, B. Pollio¹¹, A. Borchiellini¹², A. Tosetto¹³, P. Flora¹⁴, P. Simioni¹ | ¹Haemophilia Center, First Chair of Internal Medicine, Department of Medicine, University-Hospital of Padua Medical School, Padua; ²Department of Human Sciences and Promotion of the Quality of Life, Unit of Clinical and Molecular Epidemiology IRCCS San Raffaele Roma Open University, Roma; Unit of Clinical and Molecular Epidemiology IRCCS San Raffaele, Roma; ³Centre for Bleeding Disorders, Careggi University Hospital of Firenze; ⁴Azienda Ospedaliero Universitaria di Parma; ⁵Hematology Division, Umberto I University Hospital of Roma; ⁶Haemophilia Center, Department of Transfusion Medicine, Hospital of Macerata; ⁷IRCCS Istituto Giannina Gaslini, Genova; ⁸Haemophilia and Transfusion Centre, Bufalini Hospital, Cesena; ⁹Children’s Hospital Bambino Gesù, Roma; ¹⁰Haemophilia Center, Department of Onco-Hematology and Radioterapy, Hospital of Reggio Calabria; ¹¹Haemophilia Pediatric Center, Transfusion Medicine, City of Health and Science of Turin; ¹²City of Health and Science of Turin; ¹³Hemorrhagic and Thrombotic Diseases Unit, S. Bortolo Hospital of Vicenza; ¹⁴RCCS Foundation Ca’ Granda Maggiore Policlinico Hospital, Milan, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.233

  674

  PDF: 26
• 

  Gene therapy for hemophilia B

  Pier Mannuccio Mannucci

  12-12-2025

  https://doi.org/10.4081/btvb.2025.425

  676

  PDF: 90

  HTML: 105
• 

  Diagnostic and management practices for inherited fibrinogen disorders: a nationwide survey of Italian Hemophilia Treatment Centers

  Renato Marino, Silvia Linari, Marzia Leotta, Antonio Coppola, Chiara Biasoli, Maria Elisa Mancuso, Flora Peyvandi, Cristina Santoro, Ezio Zanon, Rita Carlotta Santoro

  02-12-2025

  https://doi.org/10.4081/btvb.2025.372

  899

  PDF: 117

  HTML: 121

  Supplementary: 78

  Appendix: 79

• CO-01 | BLEEDING EVENTS IN MILD HEMOPHILIA A AND VON WILLEBRAND DISEASE TYPE 1 YEARLY TREATABLE WITH DESMOPRESSIN IN ITALY A. Gringeri^1|2, P.M. Mannucci³, G.C. Castaman⁴, F. Peyvandi^3|5 | ¹Fondazione Charta, Milano, Italy; ²Centro di Sanità Solidale, Lucca, Italy; ³Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center and Fondazione Luigi Villa, Milano, Italy; ⁴Centre for Bleeding Disorders and Coagulation, Careggi University Hospital, Firenze, Italy; ⁵Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Italy

  Alessandro Gringeri

  14-10-2026

  https://doi.org/10.4081/btvb.2026.611

  12

  PDF: 3

• CO-52 | CARDIOVASCULAR EVENTS AND SUBCLINICAL ATHEROSCLEROSIS IN HEMOPHILIA A AND B PATIENTS: A MULTICENTER COHORT STUDY A. Napolitano, E. Zanon, L. Spiezia, G. Camporese, P. Scarinzi, F. Ahmad, G. Saggiorato, C. Bulato, S. Toffanin, S. Gavasso, F. Sartorello, C. Simion, E. Campello, P. Simioni | Hemophilia Center, University Hospital of Padua, Italy

  Angela Napolitano

  14-10-2026

  https://doi.org/10.4081/btvb.2026.662

  11

  PDF: 2

• CO-76 | MILD HEMOPHILIA A CARRIER WITH CONCOMITANT STORAGE POOL DISEASE: DIAGNOSTIC CHALLENGES IN A SYMPTOMATIC FEMALE PATIENT A. Strangio, M. Leotta. A. Ierardi, R.C. Santoro | Hemophilia center, AOU Renato Dulbecco, Catanzaro, Italy

  Alessandra Strangio

  14-10-2026

  https://doi.org/10.4081/btvb.2026.686

  9

  PDF: 5

• CO-51 | HEMOSTATIC AND CARDIOVASCULAR PROFILES IN HEMOPHILIA PATIENTS WITH AND WITHOUT ATHEROSCLEROSIS A. Napolitano, E. Zanon, L. Spiezia, G. Camporese, P. Scarinzi, F. Ahmad, G. Saggiorato, C. Bulato, S. Toffanin, S. Gavasso, F. Sartorello, C. Simion, E. Campello, P. Simioni | Hemophilia Center, University Hospital of Padua, Italy

  Angela Napolitano

  14-10-2026

  https://doi.org/10.4081/btvb.2026.661

  10

  PDF: 1

• CO-21 | FUSION 2: VALIDATION AND CLINICAL PERFORMANCE OF AN INTEGRATED ULTRASOUND–FUNCTIONAL ASSESSMENT SYSTEM IN HEMOPHILIA M.E. Susi¹, E.A. Boccalandro², A. Giuffrida³, I. Ricca⁴, P. Imazio⁵, E. Bonetti⁶, I. Nichele⁷ B. Pollio⁸, E. Zanon⁹, E. Baldacci¹⁰, C. Santoro¹⁰, G. Delios⁴, S. Ligia¹⁰, M. Biglietto¹⁰, I. Calcaterra¹¹, M. Napolitano¹², M. Bodini², C. Simion⁹, B. Borsellino⁸, G. Pasta¹³, M.N.D. Di Minno¹¹, C. Martinoli^14|15 | ¹DIMES, Department of Experimental Medicine, University of Genoa, Italy; ²Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center and Fondazione Luigi Villa, Milano, Italy; ³Hemophilia Center, Borgo Roma Hospital, Integrated University Hospital of Verona, Italy; ⁴Immunology and Transfusion Medicine Service, Hemophilia Center, Ivrea Hospital, Local Health Authority TO4, Ivrea, Italy; ⁵Rehabilitation and Functional Recovery Service, Pediatric Orthopedics Unit, Regina Margherita Children’s Hospital, City of Health and Science University Hospital of Turin, Italy; ⁶Pediatric Oncohematology Unit, Borgo Trento Hospital, Integrated University Hospital of Verona, Italy; ⁷Haemophilia and Thrombosis Center, Haematology Department, San Bortolo Hospital, Vicenza, Italy; ⁸Transfusion Medicine and Immunohematology Service, Regina Margherita Children’s Hospital, City of Health and Science University Hospital of Turin, Italy; ⁹Coagulation Disorders and Hemophilia Center, University Hospital of Padova, Italy; ¹⁰Unit of Special Diagnosis and Therapy of Hemostasis and Thrombosis, Hematology Department, Policlinico Umberto I, Sapienza University of Rome, Italy; ¹¹Department of Clinical Medicine and Surgery, Regional Reference Centre for Coagulation Disorders, Federico II University, Napoli, Italy; ¹²Dipartimento PROMISE, Università degli Studi di Palermo and UOC Ematologia e Malattie Rare, PO “Cervello”, Palermo, Italy; ¹³Orthopedics and Traumatology Clinic, IRCCS Policlinico San Matteo Foundation, Pavia, Italy; ¹⁴DISSAL, Department of Health Sciences, University of Genoa, Italy; ¹⁵UOC Emergency and Musculoskeletal Radiology, IRCCS AOM San Martino Hospital, Genova, Italy

  Maria Elena Susi

  14-10-2026

  https://doi.org/10.4081/btvb.2026.631

  8

  PDF: 1
• 

  Diagnostic challenges in current laboratory practice at Italian Hemophilia Centers: findings from a nationwide survey

  Tiziano Martini, Alessandra Valpreda, Marina Marchetti, Alberto Catalano, Laura Contino, Raimondo De Cristofaro, Augusto Bramante Federici, Ilaria Quaglia, Rossana Rossi, Rita Carlotta Santoro, Armando Tripodi, Angelo Claudio Molinari

  12-03-2026

  https://doi.org/10.4081/btvb.2026.431

  414

  PDF: 109

  Supplementary: 51

• CO-26 | CLINICAL, LABORATORY AND METABOLIC CHARACTERISTICS OF ADULT PATIENTS WITH HEMOPHILIA A J. Di Paolo, M. Di Loreto, R. Malizia, M. Luongo, P. Massaro, M. Di Mascio, S. Verna | Immunohematology Service, Asl 02 Abruzzo, Chieti, Italy

  Josephine Di Paolo

  14-10-2026

  https://doi.org/10.4081/btvb.2026.636

  10

  PDF: 2

• CO39 | Artificial intelligence in hemophilia management: challenging the need for experts G. Sottilotta¹, D. Megalizzi¹, F. Luise² | ¹UOSD Microcitemie - Emostasi e Trombosi. Grande Ospedale Metropolitano Bianchi-Melacrino-Morelli, Reggio Calabria; ²Laboratorio Analisi, Grande Ospedale Metropolitano Bianchi-Melacrino-Morelli, Reggio Calabria, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.246

  604

  PDF: 13
• 

  Bioequivalence of von Willebrand factor-containing concentrates: implications for the choice in patients with von Willebrand disease. A position paper from the Italian Association of Hemophilia Centers

  Ezio Zanon, Giancarlo Castaman, Augusto Bramante Federici, Maria Elisa Mancuso, Gianfranco Pasut, Alberto Tosetto, Angiola Rocino, Rita Carlotta Santoro

  26-01-2026

  https://doi.org/10.4081/btvb.2026.415

  1270

  PDF: 337

  HTML: 163

• CO-32 | TRAUMA MANAGEMENT IN SEVERE HEMOPHILIA A: A CASE REPORT J. Di Paolo, R. Malizia, M. Luongo, P. Massaro, M. Di Mascio, S. Verna | Immunohematology Service, ASL 02 Abruzzo, Chieti, Italy

  Josephine Di Paolo

  14-10-2026

  https://doi.org/10.4081/btvb.2026.642

  8

  PDF: 1

• CO-18 | PSYCHOMETRIC ASSESSMENT OF PATIENT REPORTED EXPERIENCES WITH ARTIFICIAL INTELLIGENCE TOOLS IN HEMOPHILIA CARE G. Sottilotta ^1|2 , G. Praticò ¹ , D. Megalizzi ¹ , M. Hart ² , C. Komar ² , F. Luise ³ | ¹ UOSD Centro Microcitemie - Servizio Emostasi e Trombosi. Grande Ospedale Metropolitano di Reggio Calabria, Italy; ² Save One Life Inc., USA; ³ Laboratorio Analisi. Grande Ospedale Metropolitano di Reggio Calabria, Italy

  Gianluca Sottilotta

  14-10-2026

  https://doi.org/10.4081/btvb.2026.628

  11

  PDF: 3

• CO-07 | ITALIAN RESOURCE USE IN MILD HEMOPHILIA A AND TYPE 1 VON WILLEBRAND DISEASE A. Gringeri^1|2, G.C. Castaman³ | ¹Fondazione Charta, Milano, Italy; ²Centro di Sanità Solidale, Lucca, Italy; ³Centre for Bleeding Disorders and Coagulation, Careggi University Hospital, Firenze, Italy

  Alessandro Gringeri

  14-10-2026

  https://doi.org/10.4081/btvb.2026.617

  10

  PDF: 4
• 

  Tailored therapy with turoctocog alfa pegol according to patient’s lifestyle and hemorrhagic phenotype: from clinical trial to real-life

  Ilaria Nichele, Giuseppe Carli, Alberto Tosetto

  22-04-2024

  https://doi.org/10.4081/btvb.2024.104

  1067

  PDF: 375

• CO38 | Management of pregnancy, delivery, and postpartum in Italian carriers and women with hemophilia A and B S. Linari¹, B. Pollio², A. Ferretti³, M. Napolitano⁴, E. Grandone⁵, S. Siboni⁶, Ab. Aru⁷, E. Bertoni⁸, C. Biasoli⁹, I. Cantori¹⁰, P. Di Gregorio¹¹, G. Lassandro¹², G. Sottilotta¹³, A. Strangio¹⁴, Mr. Villa¹⁵, A. Rocino¹⁶, G. Castaman¹ | ¹Center for Bleeding Disorders and Coagulation, Careggi University Hospital, Firenze; ²Regional Reference Center for Inherited Bleeding and Thrombotic Disorders, Transfusion Medicine, Regina Margherita Children Hospital, Turin; ³Center for Hemorrhagic and Thrombotic Diseases, IRCCS A. Gemelli University Hospital Foundation, Roma; ⁴Department of Health Promotion, Maternal-Childhood, Internal Medicine of Excellence G. D’Alessandro, University of Palermo; ⁵Thrombosis and Hemostasis Unit, Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo; ⁶Angelo Bianchi Bonomi Hemophilia and Thrombosis Center and Fondazione Luigi Villa, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan; ⁷Pediatric Onco-Hematology Center, Microcitemico Hospital Cagliari; ⁸Pediatric Oncohematology and Bone Marrow Transplant “BMT” Unit, Children’s Hospital, Spedali Civili, Brescia; ⁹Hemophilia and Transfusion Center, Bufalini Hospital, Cesena; ¹⁰Hemophilia Center, Department of Transfusion Medicine, Hospital of Macerata; ¹¹Transfusion Medicine Department, SS. Annunziata Hospital, Chieti; ¹²B. Trambusti General and Specialised Pediatrics Unit, Giovanni XXIII Hospital, University of Bari; ¹³Hemophilia Center, Grande Ospedale Metropolitano, Reggio Calabria; ¹⁴Center for Hemorrhagic and Thrombotic Disorders, Pugliese Ciaccio Hospital, Catanzaro; ¹⁵Hemophilia and Thrombosis Center, Haematology Unit, Ospedale del Mare Hospital, Naples; ¹⁶Past President of the Italian Association of Hemophilia Centers, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.245

  575

  PDF: 15

• CO-12 | BEYOND CLOTTING FACTORS: NURSING AS A CORNERSTONE OF LIFELONG HEMOPHILIA CARE M.V. Puliga¹, C. Manzi², A. Besagni³, S. Linari¹, C. Carulli⁴, M. Morfini⁵ | ¹SODc Malattie Emorragiche e della Coagulazione, AOU Careggi, Firenze, Italy; ²SSD Malattie Emorragiche Congenite, IRCCS Policlinico Sant'Orsola, Bologna, Italy; ³Indipendente, Italy; ⁴Clinica Ortopedica, Università di Firenze, SOD Ortopedia, AOU Careggi, Firenze, Italy; ⁵Associazione Italiana Centri Emofilia, AICE, Milano, Italy

  Maria-Virginia Puliga

  14-10-2026

  https://doi.org/10.4081/btvb.2026.622

  13

  PDF: 2

• CO-31 | WHEN NECK PAIN HIDES A SPINAL BLEED: ANTERIOR CERVICAL EPIDURAL HEMATOMA IN A CHILD WITH HEMOPHILIA B E. Dalla Porta, C. Simion, E. Zanon, B. Stocco, L. Spiezia, P. Simioni | Hemophilia Center, University Hospital of Padua, Italy

  Edoardo Dalla Porta

  14-10-2026

  https://doi.org/10.4081/btvb.2026.641

  11

  PDF: 2

• BEST-07 | ULTRASOUND EVALUATION AND JOINT SCORING IN MILD HEMOPHILIA A: A SINGLE-CENTER CASE SERIES FOR THE IDENTIFICATION OF SUBCLINICAL ARTHROPATHY M. Leotta, A. Strangio, R.C. Santoro | Hemophilia Hemostasis and Thrombosis Unit, Azienda Ospedaliero Universitaria Renato Dulbecco, Catanzaro, Italy

  Marzia Leotta

  14-10-2026

  https://doi.org/10.4081/btvb.2026.607

  10

  PDF: 3

• CO-02 | NEONATAL GENOMIC SCREENING ENABLES PRE-SYMPTOMATIC DIAGNOSIS AND PREVENTIVE MANAGEMENT OF HEMOPHILIA B. Borsellino¹, B. Pollio¹, P. Quarello^2|3, T. Martini¹, C. Linari⁴, M. Carabotta⁵, C. Cagnazzo², S. Minucci⁶, F. Fagioli^2|3 | ¹Paediatric Haemophilia Centre, Immune-Haematology and Transfusion Medicine, University Hospital "Città della Salute e della Scienza", Torino, Italy; ²Paediatric Onco-Hematology, Stem Cell Transplantation and Cellular Therapy Division, Regina Margherita Children’s Hospital, Torino, Italy; ³Department of Paediatric and Public Health Sciences, University of Turin, Italy; ⁴Department of Laboratory Medicine, Azienda Ospedaliera Universitaria Città della Salute e della Scienza, Torino, Italy; ⁵Department of Pediatrics, G. d'Annunzio University, Chieti, Italy; ⁶Italian Institute for Genomic Medicine, IRCCS, Candiolo, Italy

  Beatrice Borsellino

  14-10-2026

  https://doi.org/10.4081/btvb.2026.612

  13

  PDF: 4
• 

  The evolving landscape of gene therapy for congenital severe hemophilia: a 2024 state of the art

  Giovanni Di Minno, Gaia Spadarella, Ilenia Lorenza Calcaterra, Giancarlo Castaman, Paolo Simioni, Raimondo De Cristofaro, Cristina Santoro, Flora Peyvandi, Matteo Di Minno

  04-09-2024

  https://doi.org/10.4081/btvb.2024.144

  2070

  PDF: 359

  SUPPLEMENTARY MATERIAL: 217

• CO32 | Major surgery in patients with severe hemophilia A without inhibitors receiving prophylaxis with fitusiran E. Zanon, C. Simion, A. Napolitano, L. Spiezia, P. Simioni | Haemophilia Center, First Chair of Internal Medicine, Department of Medicine, University-Hospital of Padua Medical School, Padua, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.239

  549

  PDF: 18

• CO-49 | JOINT STATUS EVALUATION BY ULTRASOUND AND FUNCTIONAL ASSESSMENT IN PERSONS WITH NON SEVERE HEMOPHILIA ON PROPHYLAXIS WITH FOCUS ON THOSE WITH 5-YR FOLLOW UP G. Quintavalle¹, M.I. Tassoni¹, B.M. Roccon¹, G.F. Rivolta¹, C. Costantino², R.M. Polo³, A. Matichecchia¹, A. Tagliaferri¹, A. Coppola¹ | ¹SSD Centro Hub Emofilia e Malattie Emorragiche Congenite, Az. Ospedaliero-Universitaria di Parma, Italy; ²SSD Riabilitazione Ambulatoriale e Ortogeriatrica, Az. Ospedaliero-Universitaria di Parma, Italy; ³Clinica Ortopedica, Az. Ospedaliero-Universitaria di Parma, Italy

  Gabriele Quintavalle

  14-10-2026

  https://doi.org/10.4081/btvb.2026.659

  10

  PDF: 2

• CO-55 | DEVELOPMENT OF ENGINEERED LONG-ACTING BYPASSING FX VIA ALBUMIN FUSION FOR HEMOPHILIA WITH INHIBITORS A. Martucci¹, R. Tarantino¹, K.H. Aaen², M. Pinotti¹, J.T. Andersen², A. Branchini¹ | ¹Department of Life Sciences and Biotechnology, University of Ferrara, Ferrara, Italy; ²Institute of Clinical Medicine, Department of Pharmacology, University of Oslo, Norway

  Alessandro Martucci

  14-10-2026

  https://doi.org/10.4081/btvb.2026.665

  9

  PDF: 2

• CO30 | Joint prosthetic surgery in patients with hemophilia A: clinical-functional outcomes and quality of life E. Zanon¹, A. Napolitano¹, A. Berizzi², P. Simioni¹ | ¹Haemophilia Center, First Chair of Internal Medicine, Department of Medicine, University-Hospital of Padua Medical School, Padua; ²Orthopedics and Traumatology Unit, University-Hospital of Padua Medical School, Padua, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.236

  684

  PDF: 29

• CO-24 | BALANCING BLEEDING AND THROMBOSIS: SAFETY OF LOW-MOLECULAR-WEIGHT HEPARIN THROMBOPROPHYLAXIS IN PATIENTS WITH HEMOPHILIA UNDERGOING MAJOR SURGERY S. Bergonzi^1|2|3, G. Murante^1|2|3, M. Capetta^1|2|3, F. Valeri^1|2, C. Dainese^1|2, A. Valpreda^3|4, R. Pastorino^3|4, F. Bocchi^3|4, B. Bruno^2|3, A. Borchiellini^1|2 | ¹Regional Centre for Hemorrhagic and Thrombotic Diseases, AOU Città della Salute e della Scienza, Torino, Italy; ²Division of Hematology, AOU Città della Salute e della Scienza, University of Turin, Italy; ³Department of Molecular Biotechnology and Health Sciences, University of Turin, Italy; ⁴Central Laboratory Baldi and Riberi, AOU Città della Salute e della Scienza, University of Turin, Italy

  Sara Bergonzi

  14-10-2026

  https://doi.org/10.4081/btvb.2026.634

  10

  PDF: 1

• CO-03 | BEYOND CONVENTIONAL TESTING: NANOPORE LONG-READ SEQUENCING FOR RECURRENT F8 INVERSIONS IN HEMOPHILIA A A. Taiani^1|2, F. Riccardi¹, L. Cozzuto⁴, A. Delgado⁴, S. Busciglio^1|2, G. Quintavalle¹, A. Matichecchia¹, I. Tassoni¹, B.M. Roccon¹, I. R. Cannizzaro², A. Luberto², J. Ponomarenko⁴, A. Percesepe³, V. Barili², A. Coppola¹ | ¹Regional Hub Center for Hemophilia and Congenital Bleeding Disorders, University Hospital of Parma, Italy; ²Medical Genetics, Department of Medicine and Surgery, University of Parma, Italy; ³Medical Genetics, University Hospital of Parma, Italy; ⁴Centre Genomic Regulation, CRG, Barcelona, Spain

  Antonietta Taiani

  14-10-2026

  https://doi.org/10.4081/btvb.2026.613

  10

  PDF: 2

• PO47 | Hemophilia A and antithrombin deficiency: a case of natural hemostatic rebalancing L. Torrieri, S. Ligia, E. Baldacci, R. Mormile, S. Sorella, R. Ciciani, M. Biglietto, N. Zhdanovskaya, A. Delli Paoli, A. Tirnetta, M. Lorenzon, C. Santoro | Hematology, Department of Translational and Precision Medicine, Policlinico Umberto I, Sapienza University of Roma, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.316

  614

  PDF: 11

• CO-23 | PERIOPERATIVE MANAGEMENT OF MILD-TO-MODERATE HEMOPHILIA: A COMPARATIVE STUDY OF EXTENDED HALF-LIFE VERSUS STANDARD HALF-LIFE CONCENTRATES ON CLINICAL OUTCOMES AND FACTOR CONSUMPTION M. Capetta^1|2|3, F. Valeri^1|2, C. Dainese^1|2, S. Bergonzi^1|2|3, G. Murante^1|2|3, A. Valpreda⁴, R. Pastorino^1|3, F. Bocchi^1|3, B. Bruno^2|3, A. Borchiellini^1|2 | ¹Regional Centre for Hemorrhagic and Thrombotic Diseases, AOU Città della Salute e della Scienza, Torino, Italy; ²Division of Hematology, AOU Città della Salute e della Scienza, University of Turin, Italy; ³Department of Molecular Biotechnology and Health Sciences, University of Turin, Italy; ⁴Central Laboratory Baldi and Riberi, AOU Città della Salute e della Scienza, University of Turin, Italy

  Matilde Capetta

  14-10-2026

  https://doi.org/10.4081/btvb.2026.633

  12

  PDF: 2

• CO-86 | A RARE CASE OF ACQUIRED HEMOPHILIA A ASSOCIATED WITH MYELOPROLIFERATIVE NEOPLASM A. Ierardi, A. Strangio, M. Leotta, R.C. Santoro | Hemophilia, Hemostasis and Thrombosis Unit, Azienda Ospedaliero Universitaria Renato Dulbecco, Catanzaro, Italy

  Antonella Ierardi

  14-10-2026

  https://doi.org/10.4081/btvb.2026.696

  9

  PDF: 4

• CO-29 | A RARE BLEEDING PRESENTATION IN MODERATE HEMOPHILIA A: PARAVESICAL HEMATOMA WITH PENOSCROTAL EXTENSION MIMICKING A UROLOGICAL EMERGENCY B. Stocco, C. Simion, E. Zanon, E. Dalla Porta, P. Simioni | Hemophilia Center, University Hospital of Padua, Italy

  Benedetta Stocco

  14-10-2026

  https://doi.org/10.4081/btvb.2026.639

  7

  PDF: 3

• PO02 | Pregnancy and delivery in women with hemophilia and carriers are still challenging: a ten years analysis from The Italian Association of Hemophilia Centers (AICE) M. Napolitano¹, M. Mattana², C. Cammarata¹, M. Leotta³, S. Linari⁴, M.E. Mancuso⁵, G. F. Rivolta⁶, C. Santoro⁷, L. Valdrè⁸, R.C. Santoro³, S. Siragusa¹ | ¹Department of Health Promotion, Mother and Child Care, Internal Medicine and Med, Palermo; University of Palermo, Italy; ²Department of Precision Medicine in Medical, Surgical and Critical Care “Me. Pre. Cc”, University of Palermo; ³Hemostasis and Thrombosis Unit, Azienda Ospedaliera Universitaria Dulbecco, Catanzaro; ⁴Center for Bleeding Disorders, Careggi University Hospital, Firenze; ⁵Center for Thrombosis and Hemorrhagic Diseases, IRCCS Humanitas Research Hospital, Rozzano, Milan; ⁶Regional Reference Center for the Treatment of Congenital Hemorrhagic Diseases, Parma University Hospital, Parma; ⁷Hematology, University Hospital Policlinico Umberto I, Roma; ⁸Inherited Bleeding Disorders Unit, IRCCS AOUBO, Bologna, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.312

  679

  PDF: 19

• PO78 | Acquired hemophilia A as a paraneoplastic syndrome: two cases report on a rare coexistence M. Gagliardi, L. Capone, A. Ciampa | Centro Emostasi, AORN Moscati, Avellino, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.347

  627

  PDF: 19

• CO-28 | SYNERGISTIC EFFECT OF RECOMBINANT FACTOR INFUSION ON THROMBIN GENERATION IN HEMOPHILIA PATIENTS UNDER EMICIZUMAB OR CONCIZUMAB PROPHYLAXIS F. Bocchi^1|2, R. Pastorino^1|2, G. Murante^1|2|3, S. Bergonzi^1|2|3, M. Capetta^1|2|3, F. Valeri^2|3, C. Dainese^2|3, A. Valpreda⁴, B. Bruno^1|3, A. Borchiellini^2|3 | ¹Department of Molecular Biotechnology and Health Sciences, University of Turin, Italy; ²Regional Centre for Thrombotic and Hemorrhagic Diseases, AOU Città della salute e della Scienza di Torino, Italy; ³Division of Hematology, AOU Città della Salute e della Scienza, University of Turin, Italy; ⁴Central Lab Baldi and Riberi, AOU Città della salute e della Scienza di Torino, Italy

  Francesca Bocchi

  14-10-2026

  https://doi.org/10.4081/btvb.2026.638

  11

  PDF: 3

• CO-15 | HEMOPHILIA AND PHYSICAL ACTIVITY: A SURVEY ON THE CURRENT STATUS OF SPORTS ACCESSIBILITY IN THE ITALIAN POPULATION L. Laterza¹, M. Attanasi¹, C. Cassone², P. Giordano³, G. Lassandro³ | ¹University of Bari "Aldo Moro", Interdisciplinary of Medicine, Bari, Italy; ²Fedemo, Milano, Italy; ³Pediatric Haemophilia Center - AOUC Pol. Giovanni XXXIII, University of Bari "Aldo Moro", Italy

  Luisa Laterza

  14-10-2026

  https://doi.org/10.4081/btvb.2026.625

  11

  PDF: 4

• CO-58 | SUCCESSFUL TREATMENT WITH EFANESOCTOCOG ALFA OF INTRACRANIAL HEMORRHAGE IN A NEWBORN AFFECTED BY SEVERE HEMOPHILIA A T. Martini¹, B. Borsellino^1|2, B. Pollio¹ | ¹Hemophilia Centre, Immune-Haematology and Transfusion Medicine, University Hospital “Città della Salute e della Scienza”, Torino, Italy; ²Department of Biomedicine and Prevention, PhD in Immunology, Molecular Medicine and Applied Biotechnology, University of Rome Tor Vergata, Roma, Italy

  Tiziano Martini

  14-10-2026

  https://doi.org/10.4081/btvb.2026.668

  10

  PDF: 2
• 

  Hemophilia-free mind: a call to action

  Tiziano Martini, Chiara Gorio, Cristina Dainese, Rita Carlotta Santoro, Giancarlo Castaman

  10-03-2026

  https://doi.org/10.4081/btvb.2026.465

  529

  PDF: 124

• CO-08 | IMPLEMENTING A HUB-AND-SPOKE MODEL FOR HEMOPHILIA DIAGNOSIS AND CARE IN BURKINA FASO THROUGH TRAINING OF “HEALTH ASSISTANTS” C. Gorio¹, E. Kafando², A. Buzzi³ | ¹Oncohematology Unit ASST Spedali Civili Brescia, Italy; ²Centre Hospitalier Universitaire Charles de Gaulle, Italy; ³Fondazione Paracelso ETS, Milano, Italy

  Chiara Gorio

  14-10-2026

  https://doi.org/10.4081/btvb.2026.618

  9

  PDF: 2
• 

  Palestinian patients associations appeal on World Hemophilia Day

  Sara Mellano

  17-04-2024

  https://doi.org/10.4081/btvb.2024.136

  794

  PDF: 261

• CO-33 | REAL-WORLD EXPERIENCE WITH MARSTACIMAB PROPHYLAXIS IN SEVERE HEMOPHILIA A WITHOUT INHIBITORS AND ADVANCED HEMOPHILIC ARTHROPATHY A. Casson¹, I. Ricca¹, A. Barchieri¹, G. Guido¹, M. Tucciarone¹, P. Ocello¹, C. Francisco², P. Abrate², G. Delios¹ | ¹Centro Malattie Trombotiche ed Emorragiche - SC Servizio Trasfusionale ASL TO4, Ivrea, Torino, Italy; ²SC Farmacia Ospedaliera ASL TO4, Ivrea, Torino, Italy

  Andrea Casson

  14-10-2026

  https://doi.org/10.4081/btvb.2026.643

  11

  PDF: 2

• CO-13 | USE OF THE MULTIDIMENSIONAL HEMOPHILIA PAIN QUESTIONNAIRE IN PATIENTS WITH SEVERE HEMOPHILIA A TREATED WITH EMICIZUMAB: A PILOT CROSS-SECTIONAL, SINGLE-CENTER STUDY I.L. Calcaterra, S. Donnarumma, G. D’Errico, C. De Luca, C. Caputo, P. Ciciola, E. Cimino, M. Di Minno | Università Federico II di Napoli, Italy

  Ilenia Lorenza Calcaterra

  14-10-2026

  https://doi.org/10.4081/btvb.2026.623

  9

  PDF: 2

• CO-61 | REAL-WORLD IMPLEMENTATION OF GENE THERAPY FOR HEMOPHILIA: A SHARED PATHWAY AMONG HEALTHCARE AUTHORITY, SPECIALIST CENTERS AND PATIENT ORGANIZATIONS IN THE EMILIA-ROMAGNA REGION A. Coppola¹, L. Valdrè², C. Biasoli³, E. Ferri Grazzi⁴, E. Rozzi⁵, M. Volta⁵, R. Giroldini⁶, A. Tagliaferri¹ | ¹SSD Centro Hub Emofilia e Malattie Emorragiche Congenite, Azienda Ospedaliero-Universitaria di Parma, Italy; ²SSD Malattie Emorragiche Congenite, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Italy; ³SSI Presa in Carico delle Malattie Emorragiche e Tromboemboliche, AUSL Romagna, Ospedale Bufalini, Cesena, Italy; ⁴FEDRED, Federazione delle Associazioni Emofilici della Regione Emilia Romagna, Italy; ⁵Servizio Assistenza Ospedaliera, Malattie Rare, Direzione Generale Cura della Persona, Salute e Welfare, Regione Emilia Romagna, Italy; ⁶Area Governo del Farmaco e Dispositivi Medici, Direzione Generale Cura della Persona, Salute e Welfare, Regione Emilia Romagna, Italy

  Antonio Coppola

  14-10-2026

  https://doi.org/10.4081/btvb.2026.671

  8

  PDF: 2

• CO-46 | MILD HEMOPHILIA A AND JOINT HEALTH IN REAL LIFE: IS THAT AN EMERGING ISSUE? A SINGLE CENTER EXPERIENCE G. Murante^1|2|3, F. Valeri^1|2, S. Bergonzi^1|2|3, M. Capetta^1|2|3, C. Dainese^1|2, A. Valpreda⁴, R. Pastorino^1|3, F. Bocchi^1|3, B. Bruno^2|3, A. Borchiellini^1|2 | ¹Regional Centre for Hemorrhagic and Thrombotic Diseases, AOU Città della Salute e della Scienza of Turin, Italy; ²Division of Hematology, AOU Città della Salute e della Scienza, University of Turin, Italy; ³Dep. of Molecular Biotechnology and Health Sciences, University of Turin, Italy; ⁴Central Lab. Baldi and Riberi, AOU Città della Salute e della Scienza of Turin, Italy

  Giovanni Murante

  14-10-2026

  https://doi.org/10.4081/btvb.2026.656

  9

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• CO-30 | AL AMYLOIDOSIS IN A PATIENT WITH SEVERE HEMOPHILIA A AND INHIBITORS WHO HAD A MONOZYGOTIC TWIN: SAME GENES, DIFFERENT OUTCOMES M. Biglietto^1|2, S. Sorella¹, S. Ligia¹, C. Andriola¹, R. Mormile¹, E. Baldacci¹, A. Chistolini¹, C. Santoro¹ | ¹Hematology, Department of Translational and Precision Medicine, Sapienza University of Rome, Italy; ²Department of Molecular Biology, Sapienza University of Rome, Italy

  Mario Biglietto

  14-10-2026

  https://doi.org/10.4081/btvb.2026.640

  10

  PDF: 2

• CO-53 | LIVER FIBROSIS, STEATOSIS AND SUBCLINICAL ATHEROSCLEROSIS IN PATIENTS WITH HEMOPHILIA: A CROSS-SECTIONAL STUDY C. Simion^1|2, B. Stocco^1|2, I. Condonato^1|2, E. Dalla Porta^1|2, A. Napolitano^1|2, E. Zanon^1|2, L. Fabris¹, L. Spiezia^1|2, P. Simioni^1|2 | ¹First Chair of Internal Medicine and Thrombotic and Haemorrhagic Diseases Unit, Department of Medicine, Padova University Hospital, Italy; ²Hemophilia Center, Padova University Hospital, Italy

  Chiara Simion

  14-10-2026

  https://doi.org/10.4081/btvb.2026.663

  9

  PDF: 3

• CO28 | Cognitive, adaptive abilities and behavioral symptoms in children and adolescents with hemophilia: a pilot study R. Vallone¹, M. Luciani², A. Smigliani², M. F. Mansueto³, S. Vicari^1,4, D. Menghini¹ | ¹Child and Adolescent Neuropsychiatry Unit, Bambino Gesù Children’s Hospital, IRCCS, Roma; ²OncoHematology Unit, Bambino Gesù Children’s Hospital, IRCCS, Roma; ³Department of Oncology U.O. Hematology AUO Policlinico, Paolo Giaccone, Palermo; ⁴Department of Life Science and Public Health, Università Cattolica del Sacro Cuore, Roma, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.234

  662

  PDF: 19

• CO-77 | PERINATAL MANAGEMENT IN WOMAN WITH MILD HEMOPHILIA B: A TWIN PREGNANCY CASE T. Martini¹, B. Borsellino^1|2, B. Pollio¹ | ¹Haemophilia Centre, Immune-Haematology and Transfusion Medicine, University Hospital “Città della Salute e della Scienza”, Torino, Italy; ²Department of Biomedicine and Prevention, PhD in Immunology, Molecular Medicine and Applied Biotechnology, University of Rome Tor Vergata, Roma, Italy

  Tiziano Martini

  14-10-2026

  https://doi.org/10.4081/btvb.2026.687

  11

  PDF: 2

• CO-10 | APPLICATIONS OF ARTIFICIAL INTELLIGENCE IN HEMOPHILIA MANAGEMENT: INNOVATIONS AND FUTURE PERSPECTIVES A. Ierardi, M. Leotta, A. Strangio, S. Prejanò, R.C. Santoro | UO Hemophilia, Hemostasis and Thrombosis. Azienda Ospedaliero Universitaria Renato Dulbecco, Catanzaro, Italy

  Antonella Ierardi

  14-10-2026

  https://doi.org/10.4081/btvb.2026.620

  10

  PDF: 2
• 

  Gene transfer in hemophilia A: not cogent yet

  Pier Mannuccio Mannucci

  20-04-2022

  https://doi.org/10.4081/btvb.2022.32

  2558

  PDF: 426

• CO-42 | LONGITUDINAL THROMBIN GENERATION PROFILING IN A PATIENT WITH SEVERE HEMOPHILIA A DURING ANTITHROMBIN-LOWERING THERAPY, CANCER, AND MAJOR SURGERY C. Simion^1|2, C. Bulato¹, E. Campello^1|2, E. Zanon^1|2, B. Serena¹, S. Toffanin¹, P. Simioni^1|2 | ¹First Chair of Internal Medicine and Thrombotic and Haemorrhagic Diseases Unit, Department of Medicine, Padova University Hospital, Italy; ²Hemophilia Center, Padova University Hospital, Italy

  Chiara Simion

  14-10-2026

  https://doi.org/10.4081/btvb.2026.652

  9

  PDF: 1

• CO-20 | REAL-WORLD EXPERIENCE ON THE MANAGEMENT OF MILD HEAD INJURY IN A COHORT OF CHILDREN WITH HEMOPHILIA A WITH AND WITHOUT INHIBITORS TREATED WITH EMICIZUMAB B. Pollio¹, B. Borsellino^1|2, T. Martini¹ | ¹Haemophilia Centre, Immune-Haematology and Transfusion Medicine, University Hospital “Città della Salute e della Scienza”, Torino, Italy; ²Department of Biomedicine and Prevention, PhD in Immunology, Molecular Medicine and Applied Biotechnology, University of Rome Tor Vergata, Roma, Italy

  Tiziano Martini

  14-10-2026

  https://doi.org/10.4081/btvb.2026.630

  12

  PDF: 2
• 

  Pharmacokinetics of extended half-life albumin-fused factor IX and heterogeneous F9 variants in hemophilia B: a retrospective cohort study

  Barbara Lunghi, Massimo Morfini, Silvia Linari, Dario Balestra, Alessio Branchini, Lisa Pieri, Donata Belvini, Laura Banov, Cristina Santoro, Giancarlo Castaman, Francesco Bernardi

  02-03-2026

  https://doi.org/10.4081/btvb.2026.413

  438

  PDF: 126

  Supplementary: 94
• 

  Von Willebrand Disease (VWD) 100 years after its first description: the research of Italian investigators for a better management of VWD patients

  Augusto B. Federici, Giancarlo Castaman, Paolo Gresele, Alberto Tosetto

  09-10-2026

  https://doi.org/10.4081/btvb.2026.580

  107

  PDF: 61

• CO-39 | MYELOID CELL FUNCTION AND CYTOKINE PROFILES IN PEDIATRIC HEMOPHILIA A: INSIGHTS FROM FACTOR VIII AND EMICIZUMAB PROPHYLAXIS T. Martini¹, A. Cottonaro², S. Akula², B. Pollio¹, I. Ricca³, J. Agnelli Giacchello⁴, P. Sciancalepore⁴, R. Santi⁴, A. Follenzi^2|4, S. Merlin² | ¹Haemophilia Centre, Immune-Haematology and Transfusion Medicine, University Hospital “Città della Salute e della Scienza”, Torino, Italy; ²Department of Health Sciences, Università del Piemonte Orientale, Novara, Italy; ³Transfusion Medicine, Ivrea Hospital, Ivrea, Italy; ⁴Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo, Alessandria, Italy

  Tiziano Martini

  14-10-2026

  https://doi.org/10.4081/btvb.2026.649

  18

  PDF: 2

• CO-62 | ACCESS TO ULTRA-LONG HALF-LIFE FACTOR VIII AS THE DEFINITIVE MOTIVATION FOR IMMUNE TOLERANCE INDUCTION IN THE ERA OF NON-REPLACEMENT THERAPIES B. Borsellino¹, T. Martini¹, I. Ricca², C. Linari³, B. Pollio¹ | ¹Paediatric Haemophilia Centre, Immune-Haematology and Transfusion Medicine, University Hospital "Città della Salute e della Scienza", Torino, Italy; ²Transfusion Medicine, Ivrea Hospital, Ivrea, Italy; ³Department of Laboratory Medicine, Azienda Ospedaliera Universitaria Città della Salute e della Scienza, Turin, Italy

  Beatrice Borsellino

  14-10-2026

  https://doi.org/10.4081/btvb.2026.672

  13

  PDF: 2

• CO-04 | INTEGRATING EXPERTISE: IMPLEMENTATION OF A MULTIDISCIPLINARY PATHWAY FOR GENETIC TESTING AND COUNSELLING IN INHERITED BLEEDING DISORDERS E. Zacchi^1|2, L. Piscitelli¹, C. Manzi¹, L. Godino², F. Riccardi³, A. Vaisfeld^2|4, L. Valdrè¹ | ¹Inherited Bleeding Disorders Unit, IRCCS AOUBO, Bologna, Italy; ²Medical Genetics Unit, IRCCS AOUBO, Bologna, Italy; ³Regional Hub Centre for Hemophilia and Inherited Bleeding Disorders, University Hospital of Parma, Italy; ⁴Department of Medical and Surgical Sciences, University of Bologna, Italy

  Eliana Zacchi

  14-10-2026

  https://doi.org/10.4081/btvb.2026.614

  9

  PDF: 2

• CO-37 | STEW-EFA STUDY: MULTICENTER EVALUATION OF ONE-STAGE AND CHROMOGENIC ASSAYS FOR EFANESOCTOCOG ALFA MEASUREMENT ON STAGO AND WERFEN PLATFORMS A.C. Molinari¹, M. Marchetti², A. Catalano³, L. Contino⁴, R. De Cristofaro⁵, A.B. Federici⁶, T. Martini⁷, I. Quaglia⁸, R. Rossi⁹, R. Santoro¹⁰, A. Tripodi¹¹, A. Valpreda¹² | ¹Regional Reference Centre for Hemorrhagic Diseases, Department of Hemato-Oncology, IRCCS Istituto Giannina Gaslini, Genova, Italy; ²Department of Immunohematology and Transfusion Medicine, ASST Papa Giovanni XXIII, Bergamo, Italy; ³Società per la Promozione dell'educazione Medica (S.P.E.Me), Italy; ⁴Hemostasis and Thrombosis Unit, AOU SS Antonio e Biagio e C Arrigo, Alessandria, Italy; ⁵Dipartimento di Medicina e Chirurgia Traslazionale, Facoltà di Medicina e Chirurgia "Agostino Gemelli," Università Cattolica S. Cuore, Roma, Italy - Servizio Malattie Emorragiche e Trombotiche, Fondazione Policlinico Universitario "A. Gemelli" Istituto di Ricerca e Cura a Carattere Scientifico, Roma, Italy; ⁶School of Medicine and Surgery, University of Milan-Bicocca, Milano, Italy; ⁷Hemophilia Centre, Immune-Hematology and Transfusion Medicine, University Hospital “Città della Salute e della Scienza", Torino, Italy; ⁸Center for Thrombosis and Hemorrhagic Diseases, IRCCS Humanitas Research Hospital Rozzano, Milan, Italy; ⁹Laboratory of Clinical Chemistry and Hematology, University Hospital of Parma, Italy; ¹⁰Hemophilia, Hemostasis, and Thrombosis Unit, Azienda Ospedaliero Universitaria Dulbecco, Catanzaro, Italy; ¹¹IRCCS Ca' Granda Maggiore Hospital Foundation and Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Milano, Italy; ¹²Central Laboratory Baldi and Riberi, AOU Città della Salute e della Scienza, Turin, Italy, reference laboratory of the Regional Center for Hemostasis and Thrombosis.

  Angelo Claudio Molinari

  14-10-2026

  https://doi.org/10.4081/btvb.2026.647

  10

  PDF: 2
• 

  Efficacy, safety and surgical management with concizumab prophylaxis in three young patients affected by severe hemophilia with inhibitors

  Silvia Linari, Lisa Pieri, Raffaella Pasquino, Eleonora Piellucci, Monica Attanasio, Francesca Salvianti, Giancarlo Castaman

  11-05-2026

  https://doi.org/10.4081/btvb.2026.467

  1314

  PDF: 209

• CO-60 | A TURNING POINT IN THE MANAGEMENT OF HEMOPHILIA B WITH INHIBITORS: OUTCOMES OF CONCIZUMAB PROPHYLAXIS IN TWO CHILDREN FROM EXPLORER10 G. Quintavalle¹, A. Matichecchia¹, M.I. Tassoni¹, B.M. Roccon¹, F. Riccardi¹, R.P. Serra², A. Tiri², P. Bertolini², A. Tagliaferri¹, A. Coppola¹ | ¹Regional Hub Center for Hemophilia and Congenital Bleeding Disorders, University Hospital of Parma, Italy; ²Pediatric Hematology-Oncology Unit, University Hospital of Parma, Italy

  Antonio Coppola

  14-10-2026

  https://doi.org/10.4081/btvb.2026.670

  9

  PDF: 2

• PO86 | Emicizumab in patients with moderate hemophilia A and severe bleeding phenotype: single-center real-world experience A.L. Faccini, M. Biglietto, S. Sorella, E. Crisanti, M. Antonacci, R. Mormile, R. Ciciani, E. Baldacci, C. Santoro, S. Ligia | Hematology, Department of Translational and Precision Medicine Sapienza University of Roma, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.355

  738

  PDF: 20

• CO-16 | VIRTUAL EVALUATIONS OF JOINT HEALTH USING WEARABLE SENSORS IN PERSONS WITH HEMOPHILIA: THE VESPA STUDY PROTOCOL S. Riva, R. Mahaffey | St. Mary's University London, UK

  Silvia Riva

  14-10-2026

  https://doi.org/10.4081/btvb.2026.626

  9

  PDF: 5
• 

  Is non-alcoholic fatty liver disease a prothrombotic risk factor?

  Niccolò Bitto, Vincenzo La Mura, Anna Ludovica Fracanzani, Armando Tripodi

  19-05-2023

  https://doi.org/10.4081/btvb.2023.81

  1128

  PDF: 540

• CO-59 | CONCIZUMAB IN A YOUNG CHILD WITH SEVERE HEMOPHILIA B WITH INHIBITOR: EFFECTIVE BLEED CONTROL AND SAFE HOME MANAGEMENT T. Martini¹, B. Borsellino^1|2, B. Pollio¹ | ¹Hemophilia Centre, Immune-Haematology and Transfusion Medicine, University Hospital “Città della Salute e della Scienza”, Torino, Italy; ²Department of Biomedicine and Prevention, PhD in Immunology, Molecular Medicine and Applied Biotechnology, University of Rome Tor Vergata, Roma, Italy

  Tiziano Martini

  14-10-2026

  https://doi.org/10.4081/btvb.2026.669

  14

  PDF: 2

• CO-22 | CLINICAL FEATURES IN PATIENTS WITH NON-SEVERE HEMOPHILIA A: THE DISCOVERY SCORE PROPOSAL FOR PROPHYLAXIS PRESCRIPTION M.N.D. Di Minno¹, E. Baldacci², C. Biasoli³, A. Borchiellini⁴, F. Daniele⁵, P. Di Gregorio⁶, C. Gorio⁷, G. Malcangi⁸, E. Marchesini⁹, I. Ricca¹⁰, R. Santoro¹¹, S. Siragusa¹², M.R. Villa¹³, E. Zanon¹⁴, A. Tagliaferri¹⁵, A. Coppola¹⁵ | ¹Hub Centre for Thrombotic and Hemorrhagic Disorders, Federico II University Hospital, Napoli, Italy; ²Haematology, University Hospital Policlinico Umberto I, Roma, Italy; ³Interdepartmental Simple Structure for the Management of Hemorrhagic and Thromboembolic Diseases, M. Bufalini Hospital, Cesena, Italy; ⁴Regional Centre for Hemorrhagic and Thrombotic Diseases, AOU Città della Salute e della Scienza, Torino, Italy; ⁵Haemostasis and Thrombosis Service, Ospedale Civile dell'Annunziata, Cosenza, Italy; ⁶Transfusion Medicine Department, "SS. Annunziata" Hospital, Chieti, Italy; ⁷Pediatric Onco-Hematology Unit, Children's Hospital, ASST-Spedali Civili, Brescia, Italy; ⁸Haemophilia and Thrombosis Center, University Hospital Policlinico-Giovanni XXIII, Bari, Italy; ⁹Hemophilia Centre, SC Vascular and Emergency Department, University of Perugia, Italy; ¹⁰Centro Emofilia, Città della Salute e della Scienza, Torino, Italy; ¹¹Hemostasis and Thrombosis Unit, Azienda Ospedaliero Universitaria Dulbecco, Catanzaro, Italy; ¹²Centro di Riferimento Regionale per le Emocoagulopatie Congenite, Palermo, Italy; ¹³Hematology Unit, Ospedale Santa Maria di Loreto, Napoli, Italy; ¹⁴Hemophilia and Thrombosis Center, University Hospital of Padua, Italy; ¹⁵Hemophilia and Thrombosis Center, Azienda Ospedaliera di Parma, Italy

  Matteo Di Minno

  14-10-2026

  https://doi.org/10.4081/btvb.2026.632

  11

  PDF: 2

• CO-34 | SIMPLIFIED PERIOPERATIVE MANAGEMENT WITH N8-GP (TUROCTOCOG ALFA PEGOL) IN MAJOR ABDOMINAL SURGERY IN MILD HEMOPHILIA A WITH SEVERE BLEEDING PHENOTYPE: A CASE REPORT J. Di Paolo, R. Malizia, M. Luongo, P. Massaro, M. Di Mascio, S. Verna | Immunohematology Service, ASL 02 Abruzzo, Chieti, Italy

  Josephine Di Paolo

  14-10-2026

  https://doi.org/10.4081/btvb.2026.644

  8

  PDF: 2

• PO44 | Emicizumab in acquired haemophilia A M. Leotta, A. Strangio, A. Ierardi, S. Prejanò, R C. Santoro | Hemostasis and Thrombosis Unit, Department Hemato-Oncology, Azienda Ospedaliero-Universitaria Renato; Dulbecco, Catanzaro, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.307

  615

  PDF: 19

• CO-75 | ASSAY DISCREPANCY IN HEMOPHILIA A CARRIERS: CLINICAL AND GENETIC INSIGHTS M. Leotta, A. Strangio, A. Ierardi, R.C. Santoro | Hemophilia Treatment Center AOU Dulbecco, Catanzaro, Italy

  Marzia Leotta

  14-10-2026

  https://doi.org/10.4081/btvb.2026.685

  9

  PDF: 5

• CO33 | Acquired hemophilia A in Liguria, Italy: what six years of data reveal C. Vernarecci¹, A. C. Molinari¹, P. Ballarino², M. Caiti², E. Cenni², P. Moscatelli², L. Banov¹ | ¹IRCCS Istituto Giannina Gaslini, Genova; ²IRCCS Policlinico San Martino, Genova, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.240

  602

  PDF: 25

• PO67 | Pancreatic cancer in a 71-year-old severe hemophilia A patient with inhibitors and sustained zero bleeding during emicizumab prophylaxis M. Biglietto, A.L. Faccini, S. Sorella, E. Crisanti, M. Antonacci, A. Taglietti, M. Gherardini, A. Tirnetta, S. Ligia, R. Mormile, R. Ciciani, E. Baldacci, C. Santoro | Hematology, Department of Translational and Precision Medicine Sapienza University of Roma, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.336

  649

  PDF: 24

• CO-27 | INNOVATIVE USE OF EPTACOG BETA TO TREAT ACUTE ELBOW HEMARTHROSIS IN A PEDIATRIC PATIENT WITH HEMOPHILIA B AND A HISTORY OF INHIBITORS, UNDERGOING SECONDARY PROPHYLAXIS WITH CONCIZUMAB L. Laterza¹, P. Giordano², G. Lassandro² | ¹University of Bari "Aldo Moro", Interdisciplinary Department of Medicine, Bari, Italy; ²Pediatric Haemophilia Center-AOUC Pol. Giovanni XXXIII, University of Bari “Aldo Moro”, Bari, Italy

  Luisa Laterza

  14-10-2026

  https://doi.org/10.4081/btvb.2026.637

  11

  PDF: 2

• CO-67 | CONGENITAL DYSFIBRINOGENEMIA: BLEEDING PHENOTYPE, THROMBOTIC COMPLICATIONS, AND LONG-TERM MANAGEMENT IN A MULTICENTER COHORT M. Biglietto^1|2, M. Presti¹, R.C. Santoro³, I. Nichele⁴, M. Napolitano⁵, S. Pasca⁶, A. Borchiellini⁷, B. Pollio⁸, E. Zanon⁹, G. Barillari¹⁰, A. Poz¹⁰, S. Sorella¹, S. Ligia¹, R. Mormile¹, E. Baldacci¹, G. Castaman¹¹, F. Peyvandi^12|13, C. Santoro¹ | ¹Hematology, Department of Translational and Precision Medicine, Sapienza University of Rome, Italy; ²Department of Molecular Biology, Sapienza University of Rome, Italy; ³Hemostasis and Thrombosis Unit, Azienda Ospedaliera Pugliese-Ciaccio, Catanzaro, Italy; ⁴Hematology Unit, Azienda ULSS 8 Berica - San Bortolo Hospital, Vicenza, Italy; ⁵Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, University of Palermo, Italy; ⁶Coagulation Diseases Center, Transfusion Medicine Department - Azienda Sanitaria Universitaria Integrata del Trentino, Trento, Italy; ⁷Centro di Riferimento Regionale Malattie Emorragiche e Trombotiche dell'Adulto, Divisione di Ematologia, Università Città della Salute e della Scienza di Torino, Italy; ⁸SIMT Immunohematology and Transfusion Medicine Service, Diagnostic Department, A.O. Città della Salute e della Scienza, Torino, Italy; ⁹Department of Medicine, Haemophilia Centre, University Hospital of Padua, Italy; ¹⁰Center for Hemorrhagic and Thrombotic Diseases, General and University Hospital S. Maria della Misericordia, Udine, Italy; ¹¹Centre for Bleeding Disorders and Coagulation, Careggi University Hospital, Firenze, Italy; ¹²IRCCS Fondazione Ca' Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Milano, Italy; ¹³Università degli Studi di Milano, Department of Pathophysiology and Transplantation, Milano, Italy

  Mario Biglietto

  14-10-2026

  https://doi.org/10.4081/btvb.2026.677

  10

  PDF: 2

• CO-50 | LEFT ATRIAL APPENDAGE OCCLUSION IN PATIENTS WITH ATRIAL FIBRILLATION AND BLEEDING DISORDERS: A SINGLE-CENTER EXPERIENCE B.M. Roccon¹, M.I. Tassoni¹, G. Quintavalle¹, G. Benatti², F. Gurgoglione², R. Rossi³, C. Cattabiani³, L. Vignali², A. Tagliaferri¹, A. Coppola¹ | ¹SSD Centro Hub Emofilia e Malattie Emorragiche Congenite, Azienda Ospedaliero-Universitaria di Parma, Italy; ²SSD Cardiologia Interventistica, Azienda Ospedaliero-Universitaria di Parma, Italy; ³Laboratorio di Coagulazione, UOC Patologia Clinica, Azienda Ospedaliero-Universitaria di Parma, Italy

  Antonio Coppola

  14-10-2026

  https://doi.org/10.4081/btvb.2026.660

  11

  PDF: 2
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  Growing weapons to fight hemophilia

  Pier Mannuccio Mannucci

  23-02-2023

  https://doi.org/10.4081/btvb.2023.64

  1477

  PDF: 573

• CO-57 | NXT007 PROPHYLAXIS IN PEOPLE WITH HEMOPHILIA A WITH OR WITHOUT FACTOR VIII INHIBITORS: COMBINED ANALYSIS OF TWO PHASE I/II MULTIPLE-ASCENDING-DOSE STUDIES M.E. Mancuso^1|2, M. Shima³, J.M. Staber⁴, Y.C. Chen⁵, F.J. López-Jaime⁶, M.C. Shen⁷, G. Ventriglia⁸, M. Takeyama⁹, C. Schmitt⁸, Y.S. Park¹⁰, A. Kiialainen⁸, N. Mizuno¹¹, M. Niggli⁸, T. Miyake¹¹, D. Matino¹², T. Saito¹¹, V. Jiménez-Yuste¹³, R. Kobayashi¹¹, D. Hart¹⁴, K. Nogami¹⁵ | ¹Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milano, Italy; ²Center for Thrombosis and Hemorrhagic Diseases, IRCCS Humanitas Research Hospital, Rozzano, Milano, Italy; ³Thrombosis and Hemostasis Research Center, Nara Medical University, Kashihara, Nara, Japan; ⁴Stead Family Department of Pediatrics, Carver College of Medicine, University of Iowa, Iowa City, USA; ⁵Hemophilia Care and Research Center, Tri-Service General Hospital, National Defense Medical University, Taipei, Taiwan; ⁶Servicio de Hematología, Hospital Universitario Regional de Málaga / Instituto de Investigación Biomédica de Málaga (IBIMA), Málaga, Spain; ⁷Department of Internal Medicine, Changhua Christian Hospital, Changhua, Taiwan; ⁸F. Hoffmann-La Roche Ltd, Basel, Switzerland; ⁹Division of Hemophilia, National Hospital Organization, Osaka National Hospital, Osaka, Japan; ¹⁰Department of Pediatrics, Kyung Hee University Hospital at Gangdong, Seoul, South Korea; ¹¹Chugai Pharmaceutical Co., Ltd, Tokyo, Japan; ¹²McMaster University, Hamilton, Ontario, Canada; ¹³La Paz University Hospital-IdiPAZ, Autónoma University, Madrid, Spain; ¹⁴Roche Products Ltd, Welwyn Garden City, UK; ¹⁵Department of Pediatrics, Nara Medical University, Kashihara, Nara, Japan

  Maria Elisa Mancuso

  14-10-2026

  https://doi.org/10.4081/btvb.2026.667

  10

  PDF: 3

• PO65 | Utilization of emicizumab in acquired hemophilia A: a case report C. Caputo, P. Conca, I.L. Calcaterra, E. Cimino, M. Romeo, M. Aversano, E. Franco, C. De Luca, G. D’errico, L. Jr Valletta, M. Di Minno, A. Tufano | Department of Clinical Medicine and Surgery, Federico II University, Naples, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.334

  612

  PDF: 21

• CO-81 | DIGITAL NETWORKING FOR ACQUIRED HEMOPHILIA A: A REGION-WIDE CARE PATHWAY FROM DIAGNOSIS TO FOLLOW-UP M. Mattana¹, M.F. Mansueto², S. Raso¹, S. Siragusa^2|3, R. Tomasello¹, M. Napolitano^1|3 | ¹A.O.O.R. Villa Sofia Cervello P.O. Cervello-UOC di Ematologia per le Malattie Rare del Sangue e degli Organi Ematopoietici, Palermo, Italy; ²UOC Ematologia Policlinico P.Giaccone Palermo, Italy; ³Dipartimento Promozione della Salute, Materno-Infantile, di Medicina Interna e Specialistica di Eccellenza(PROMISE), Università degli studi di Palermo, Italy

  Marta Mattana

  14-10-2026

  https://doi.org/10.4081/btvb.2026.691

  8

  PDF: 2
• 

  The key to fibrinolysis and thrombolysis

  Roger Lijnen, Désiré Collen

  09-09-2025

  https://doi.org/10.4081/btvb.2025.368

  1681

  PDF: 518

  HTML: 260

• CO-73 | WHEN BLEEDING MIMICS THROMBOSIS: DIAGNOSTIC DELAY AND THROMBOTIC COMPLICATIONS IN ACQUIRED HEMOPHILIA A R. Tomasello¹, M. Mattana¹, S. Raso¹, F. Schirò¹, P. Polidori², M.I. Di Lena³, F. La Gattuta⁴, M. Napolitano¹ | ¹Ematologia e malattie rare, PO Cervello di Palermo, Italy; ²Farmacia ospedaliera, PO Cervello di Palermo, Italy; ³Direzione medica, PO Cervello di Palermo, Italy; ⁴Radiologia interventistica, PO Villa Sofia di Palermo, Italy

  Riccardo Tomasello

  14-10-2026

  https://doi.org/10.4081/btvb.2026.683

  12

  PDF: 2

• CO-80 | EMICIZUMAB PLASMA CONCENTRATIONS AND CLINICAL OUTCOMES IN ACQUIRED HEMOPHILIA A: A REAL-WORLD SINGLE-CENTER EXPERIENCE C. Simion^1|2, E. Zanon^1|2, C. Bulato¹, B. Stocco^1|2, F. Righetto¹, F. Sartorello¹, P. Simioni^1|2 | ¹First Chair of Internal Medicine and Thrombotic and Haemorrhagic Diseases Unit, Department of Medicine, Padova University Hospital, Italy; ²Hemophilia Center, Padova University Hospital, Italy

  Chiara Simion

  14-10-2026

  https://doi.org/10.4081/btvb.2026.690

  13

  PDF: 2

• CO-25 | MILD HEMOPHILIA A AND JOINT HEALTH IN REAL LIFE: IS THAT AN EMERGING ISSUE? A SINGLE CENTER EXPERIENCE F. Valeri¹, G. Murante¹, C. Dainese¹, M. Capetta¹, S. Bergonzi¹, R. Pastorino¹, F. Bocchi¹, B. Bruno², A. Borchiellini¹ | ¹Regional Centre for Haemorrhagic and Thrombotic Disease, Hematology Division, AOU Città della Salute e della Scienza, Torino, Italy; ²Division of Hematology, AOU Città della Salute e della Scienza, Department of Molecular Biotechnology and Health sciences, University of Turin, Italy

  Federica Valeri

  14-10-2026

  https://doi.org/10.4081/btvb.2026.635

  11

  PDF: 2

• CO-89 | FEMORAL FRACTURE SURGERY IN AN ELDERLY, FRAIL PATIENT WITH ACQUIRED HEMOPHILIA A RECEIVING EMICIZUMAB PROPHYLAXIS: A CASE REPORT C. Simion^1|2, E. Zanon^1|2, B. Stocco^1|2, F. Sartorello¹, C. Bulato¹, G. Saggiorato¹, P. Simioni^1|2 | ¹First Chair of Internal Medicine and Thrombotic and Haemorrhagic Diseases Unit, Department of Medicine, Padova University Hospital, Italy; ²Hemophilia Center, Padova University Hospital, Italy

  Chiara Simion

  14-10-2026

  https://doi.org/10.4081/btvb.2026.699

  9

  PDF: 5

• CO-54 | DECREASED BONE MINERAL DENSITY IN HEMOPHILIA IS NOT CORRELATED WITH INCREASED RISK OF FRACTURES M.R. Fasulo¹, F. Carrone², G. Mazziotti^3|4, A. Colombo¹, C. Lodigiani¹, M.E. Mancuso^1|4 | ¹Center for Thrombosis and Hemorrhagic Diseases, IRCCS Humanitas Research Hospital, Rozzano, Milano, Italy; ²Endocrinology and Diabetology Unit, Humanitas Mater Domini, Castellanza, Varese, Italy; ³Endocrinology, Diabetology and Medical Andrology Unit, Metabolic Bone Diseases and Osteoporosis Section, IRCCS Humanitas Research Hospital, Rozzano, Milano, Italy; ⁴Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milano, Italy

  Maria Rosaria Fasulo

  14-10-2026

  https://doi.org/10.4081/btvb.2026.664

  11

  PDF: 3

• CO-38 | CALIBRATION OF HUMAN COAGULATION FACTOR VIII IN NOVEL QUALITY CONTROL MATERIALS: A COLLABORATIVE STUDY G. Gullifa¹, A. Carocci¹, C. Albertini^1|2, L. Luchetti¹, M.T. Pasquino¹, M. Simeoni¹, L. Mandarino¹, C. Adriano^1|3, R. Risoluti³, S. Massimi¹ | ¹Centro Nazionale per il Controllo e la Valutazione dei Farmaci, Istituto Superiore di Sanità, Roma, Italy; ²Centro Nazionale Sangue, Istituto Superiore di Sanità, Roma, Italy; ³Sapienza Università di Roma, Italy

  Giuseppina Gullifa

  14-10-2026

  https://doi.org/10.4081/btvb.2026.648

  9

  PDF: 2

• PO49 | Use of emicizumab in two patients with acquired hemophilia A: a new therapeutic approach S. Sorella, J. Micozzi, E. Baldacci, M. Biglietto, R. Mormile, A. Chistolini, R. Ciciani, L. Torrieri, N. Zhdanovskaya, M. Lorenzon, A. Delli Paoli, S. Ligia, C. Santoro | Hematology, Department of Translational and Precision Medicine, Policlinico Umberto I, Sapienza University of Roma, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.318

  651

  PDF: 21

• CO-78 | REAL-WORLD MANAGEMENT OF ACQUIRED HEMOPHILIA A: FOCUS ON RECOMBINANT PORCINE FVIII AS FIRST-LINE HEMOSTATIC TREATMENT AND LONG-TERM OUTCOMES M. Leotta, A. Strangio, A. Ierardi, R.C. Santoro | Hemophilia, Hemostasis and Thrombosis Centre, Azienda Ospedaliero Universitaria Renato Dulbecco, Catanzaro, Italy

  Marzia Leotta

  14-10-2026

  https://doi.org/10.4081/btvb.2026.688

  10

  PDF: 2
• 

  Development of a shared decision-making tool for gene therapy in hemophilia A in Italy

  Giovanni Di Minno, Sarah Bigi, Serena Barello, Enrico Ferri Grazzi, Marco Follino, Maria Francesca Mansueto, Mariasanta Napolitano, Rita Carlotta Santoro, Giancarlo Castaman

  22-06-2026

  https://doi.org/10.4081/btvb.2026.426

  912

  PDF: 128

  SUPPLEMENTARY MATERIAL: 76

• CO36 | Inhibitor titer at diagnosis and clinical course in acquired hemophilia A: a single-center experience C. Simion, B. Stocco, E. Dalla Porta, E. Campello, G. Furlan, L. Spiezia, G. Saggiorato, F. Sartorello, E. Zanon, P. Simioni | Department of Medicine – DIMED, University of Padua, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.243

  573

  PDF: 28
• 

  Safety of COVID-19 mRNA vaccination in patients with history of acquired hemophilia A: a case series

  Luca Puccetti, Vincenzo Sammartano, Federico Caroni, Margherita Malchiodi, Paola Calzoni, Eleonora Franceschini, Lucrezia Galasso, Monica Bocchia

  17-10-2022

  https://doi.org/10.4081/btvb.2022.40

  3046

  PDF: 428

• CO35 | Bleeding phenotype characterization in patients with congenital bleeding disorders: a multigenic approach using next generation sequencing to identify coagulation-modulating variants C. Simion, L. Gianesello, C. Bulato, A. Benetti, E. Campello, A. Giannella, G. Ceolotto, E. Zanon, L. Spiezia, P. Simioni | Department of Medicine – DIMED, University of Padua, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.242

  532

  PDF: 23
• 

  The changing landscape of treatment for acquired hemophilia A

  Massimo Franchini, Daniele Focosi

  30-01-2025

  https://doi.org/10.4081/btvb.2025.157

  2051

  PDF: 544

• BEST-05 | LONG-TERM EMICIZUMAB PROPHYLAXIS IN PEOPLE WITH HEMOPHILIA A: REAL-WORLD EXPERIENCE ACROSS ALL AGES A. Colombo¹, I. Quaglia¹, M.R. Fasulo¹, C. Lodigiani¹, M.E. Mancuso^1|2 | ¹Center for Thrombosis and Hemorrhagic Diseases, IRCCS Humanitas Research Hospital, Rozzano, Milano, Italy; ²Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milano, Italy

  Arianna Colombo

  14-10-2026

  https://doi.org/10.4081/btvb.2026.605

  13

  PDF: 3

• PO12 | Characterisation and real word clinical data of HEM006, a newly formulated intranasal spray desmopressin (DDAVP) to address a global treatment gap G. De Giorgi¹, A. Gringeri², R. Franceschini¹, A. Koganti³ | ¹Hemorare Srl, Italy; ²Fondazione Charta, Milan, Italy; ³Quenya LLC, USA

  22-10-2025

  https://doi.org/10.4081/btvb.2025.274

  562

  PDF: 12

• CO-70 | CONGENITAL AFIBRINOGENEMIA: BLEEDING PHENOTYPE, THROMBOTIC COMPLICATIONS, AND LONG-TERM MANAGEMENT IN A MULTICENTER COHORT M. Biglietto^1|2, M. Presti¹, R.C. Santoro³, I. Nichele⁴, M. Napolitano⁵, S. Pasca⁶, A. Borchiellini⁷, B. Pollio⁸, E. Zanon⁹, G. Barillari¹⁰, A. Poz¹⁰, S. Sorella¹, S. Ligia¹, R. Mormile¹, E. Baldacci¹, G. Castaman¹¹, F. Peyvandi^12|13, C. Santoro¹ | ¹Hematology, Department of Translational and Precision Medicine, Sapienza University of Rome, Italy; ²Department of Molecular Biology, Sapienza University of Rome, Italy; ³Hemostasis and Thrombosis Unit, Azienda Ospedaliera Pugliese-Ciaccio, Catanzaro, Italy; ⁴Hematology Unit, Azienda ULSS 8 Berica - San Bortolo Hospital, Vicenza, Italy; ⁵Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, University of Palermo, Italy; ⁶Coagulation Diseases Center, Transfusion Medicine Department - Azienda Sanitaria Universitaria Integrata del Trentino, Trento, Italy; ⁷Centro di Riferimento Regionale Malattie Emorragiche e Trombotiche dell'Adulto, Divisione di Ematologia, Università Città della Salute e della Scienza di Torino, Italy; ⁸SIMT Immunohematology and Transfusion Medicine Service, Diagnostic Department, A.O. Città della Salute e della Scienza, Torino, Italy; ⁹Department of Medicine, Haemophilia Centre, University Hospital of Padua, Italy; ¹⁰Center for Hemorrhagic and Thrombotic Diseases, General and University Hospital S. Maria della Misericordia, Udine, Italy; ¹¹Centre for Bleeding Disorders and Coagulation, Careggi University Hospital, Firenze, Italy; ¹²IRCCS Fondazione Ca' Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Milano, Italy; ¹³Università degli Studi di Milano, Department of Pathophysiology and Transplantation, Milano, Italy

  Mario Biglietto

  14-10-2026

  https://doi.org/10.4081/btvb.2026.680

  10

  PDF: 3

• CO-36 | PLATELETS MATTER: THROMBIN GENERATION IN PLATELET‐RICH-PLASMA VS. PLATELET‐POOR‐PLASMA UNDER NON-REPLACEMENT THERAPIES IN HEMOPHILIA F. Bocchi^1|2, R. Pastorino^1|2, G. Murante^1|2|3, S. Bergonzi^1|2|3, M. Capetta^1|2|3, F. Valeri^2|3, C. Dainese^2|3, A. Valpreda⁴, B. Bruno^1|3, A. Borchiellini^2|3 | ¹Department of Molecular Biotechnology and Health Sciences, University of Turin, Italy; ²Regional Centre for Thrombotic and Hemorrhagic Diseases, AOU Città della salute e della Scienza di Torino, Italy; ³Division of Hematology, AOU Città della Salute e della Scienza, University of Turin, Italy; ⁴Central Lab Baldi and Riberi, AOU Città della salute e della Scienza di Torino, Italy

  Francesca Bocchi

  14-10-2026

  https://doi.org/10.4081/btvb.2026.646

  10

  PDF: 2

• CO34 | Evaluation of emicizumab concentration and thrombin generation in a cohort of severe hemophilia A patients with and without inhibitor A. Taglietti¹, S. Ligia¹, F. Paoletti¹, R. Mormile¹, E. Baldacci², A. Chistolini¹, C. Santoro^1,2 | ¹Hematology, Department of Translational and Precision Medicine, Sapienza University of Roma; ²Hematology, Azienda Ospedaliera Universitaria Policlinico Umberto I, Roma, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.241

  663

  PDF: 11

• CO-09 | THE POSSIBLE ROLE OF THE PSYCHOLOGIST IN THE MANAGEMENT OF PATIENTS WITH CONGENITAL BLEEDING DISORDERS: THE EXPERIENCE OF A SINGLE HEMOPHILIA CENTER D. Meneghini¹, E. Tosi¹, B. Pernice², L. Del Piccolo², M. Bodini¹, A.C. Giuffrida¹ | ¹Transfusion Medicine Dep., Integrated University Hospital, Verona, Italy; ²Dep. of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Italy

  Marco Bodini

  14-10-2026

  https://doi.org/10.4081/btvb.2026.619

  9

  PDF: 2

• CO-85 | ACQUIRED HEMOPHILIA A IN LIVER CIRRHOSIS: BALANCING HEMOSTASIS BETWEEN HIGH HEMORRHAGIC AND THROMBOTIC RISKS N. Portesi, G. Martini | ASST Spedali Civili di Brescia, Italy

  Nicola Portesi

  14-10-2026

  https://doi.org/10.4081/btvb.2026.695

  10

  PDF: 5

• BEST-04 | MAJOR ORTHOPEDIC SURGERY WITH EMICIZUMAB: A SERIES OF 22 PATIENTS (40 PROCEDURES) WITH A MID-TERM FOLLOW-UP G. Daniele¹, C. Carulli¹, S. Linari², L. Pieri², G. Castaman² | ¹Clinica Ortopedica, Azienda Ospedaliero-Universitaria Careggi, Università degli Studi di Firenze, Italy; ²Centro Malattie Emorragiche e della Coagulazione, Azienda Ospedaliero-Universitaria Careggi, Firenze, Italy

  Giovanna Daniele

  14-10-2026

  https://doi.org/10.4081/btvb.2026.604

  13

  PDF: 2