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• PO39 | Bleeding events in Von Willebrand disease type 1 yearly treatable with desmopressin A. Gringeri^1,2, P.M. Mannucci³, M. Gringeri⁴, G. Castaman⁵, F. Peyvandi^3,6 | ¹Fondazione Charta, Milan; ²Centro di Sanità Solidale, Lucca; ³Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center and Fondazione Luigi Villa, Milan; ⁴Department of Medical Biotechnologies and Translational Medicine, Postgraduate School of Clinical Pharmacology and Toxicology, University of Milan; ⁵Centre for Bleeding Disorders and Coagulation, Careggi University Hospital, Firenze; ⁶Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.302

  514

  PDF: 0
• 

  PO50 | SUB-ANALYSIS OF INTERIM RESULTS FROM A PHASE 2 STUDY INVESTIGATING REGN9933^A2 AND REGN7508^CAT FOR THE PREVENTION OF CONTACT-MEDIATED VENOUS THROMBOEMBOLISM IN PATIENTS WITH ACTIVE CANCER UNDERGOING PERIPHERALLY INSERTED CENTRAL CATHETER PLACEMENT (ROXI-CATH) J. Zwicker^1,2, A.P. Kithcart³, J. Kaplan³, Y-C. Cheng³, J.G. Raya³, J. Xiao³, S. Li³, K. Musgrave⁴, D.E. Gutstein³, G. Piazza⁵ | ¹Memorial Sloan Kettering Cancer Center, New York, NY, USA; ²Weill Cornell Medical Center, New York, NY, USA; ³Regeneron Pharmaceuticals, Inc. , Tarrytown, NY, USA; ⁴Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK; ⁵Brigham and Women’s Hospital, Boston, MA, USA

  Società Italiana di Emostasi e Trombosi

  16-04-2026

  https://doi.org/10.4081/btvb.2026.542

  125

  PDF: 33

• PO09 | Comparison of different aggregometry methods for evaluation of platelet function in patients with myeloproliferative neoplasms C. Fortino, I. Bertozzi, D. Regazzo, L. Gianesello, G. Nuozzi, F. Sartorello, V. Azzaro, G. Saggiorato, A. Bertomoro, P. Simioni | First Medical Clinic, Department of Medicine – DIMED, Università degli Studi di Padova, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.271

  434

  PDF: 0

• CO23 | Markers of inflammation and hypofibrinolysis are associated with cognitive dysfunction and motor performances in atrial fibrillation patients on oral anticoagulant therapy: insights from the Strat-AF study F. Alfano^1,2, F. Cesari^1,2, A.M. Gori^1,2, M. Berteotti^1,2, E. Salvadori³, B. Giusti^1,2, A. Bertelli^1,2, F. Fratini⁴, A. Rogolino^1,2, B. Formelli^4,5, F. Pescini^4,5, E. Fainardi⁶, E. Barucci⁴, G. Salti⁵, A. Cavaliere⁴, A. Ginestroni⁶, A. Poggesi^4,5, R. Marcucci^1,2 | ¹Department of Experimental and Clinical Medicine, University of Firenze; ²Center for Atherothrombotic Diseases, Careggi University Hospital, Firenze; ³Department of Biomedical and Clinical Sciences, University of Milan; ⁴NEUROFARBA Department, Neuroscience Section, University of Firenze; ⁵Stroke Unit, Careggi University Hospital, Firenze; ⁶Neuroradiology Unit, Careggi University Hospital, Department of Experimental and Clinical Biomedical Sciences, University of Firenze, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.229

  585

  PDF: 0
• 

  PO68 | RISK OF VENOUS THROMBOEMBOLISM IN PATIENTS WITH CANCER AND MIGRAINE: A COHORT ANALYSIS AMONG DANISH NATIONAL HEALTH SURVEY PARTICIPANTS O. Rosenkrantz¹, P. Szentkúti¹, L. Amdisen¹, E. Horváth-Puhó¹, A.L. Pedersen¹, H.E. Bøtker², H. Elser^1|3, J.P. Vandenbroucke^1|4|5, H.T. Sørensen¹ | ¹Department of Clinical Epidemiology and Center for Population Medicine, Aarhus University Hospital and Aarhus University, Denmark; ²Department of Cardiology, Aarhus University Hospital, Department of Clinical Medicine, University of Aarhus, Denmark; ³Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia, PA, USA; ⁴Department of Clinical Epidemiology, Leiden University Medical School Leiden, The Netherlands; ⁵School of Hygiene and Tropical Medicine, London, UK

  Società Italiana di Emostasi e Trombosi

  16-04-2026

  https://doi.org/10.4081/btvb.2026.557

  119

  PDF: 29
• 

  Venous thromboembolism prophylaxis in orthopedic surgery: a narrative review

  Sarah Gallitto, Thomas C. Varkey, Jacob Lahti

  13-12-2024

  https://doi.org/10.4081/btvb.2024.131

  3116

  PDF: 397
• 

  PO05 | DESIGN, SYNTHESIS, AND BIOLOGICAL EVALUATION OF NOVEL IMATINIB AND NILOTINIB ANALOGUES EXPRESSING ENHANCED ANTIPLATELET AND ANTICANCER ACTIVITIES D. Pantazi¹, L. Pechlivani¹, A. Kosma¹, K. Lalechou¹, M.G. Siskos², D. Alivertis³, A.D. Tselepis¹ | ¹Atherothrombosis Research Centre, Laboratory of Biochemistry, Department of Chemistry, University of Ioannina, Greece; ²Laboratory of Organic Chemistry, Department of Chemistry, University of Ioannina, Greece; ³Department of Biological Applications and Technology, University of Ioannina, Greece

  Società Italiana di Emostasi e Trombosi

  16-04-2026

  https://doi.org/10.4081/btvb.2026.501

  161

  PDF: 35

• PO58 | Gender differences in primary haemostasis A. Becchetti², M. Brambilla², M. Conti², D. Trabattoni², E. Tremoli³, M. Camera^1,2 | ¹Department of Pharmaceutical Sciences, Università degli Studi di Milano; ²Centro Cardiologico Monzino IRCCS, Milan; ³Maria Cecilia Hospital, Cotignola (RA), Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.327

  520

  PDF: 0

• CO36 | Inhibitor titer at diagnosis and clinical course in acquired hemophilia A: a single-center experience C. Simion, B. Stocco, E. Dalla Porta, E. Campello, G. Furlan, L. Spiezia, G. Saggiorato, F. Sartorello, E. Zanon, P. Simioni | Department of Medicine – DIMED, University of Padua, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.243

  443

  PDF: 0

• CS08 | A combination of two rapid immunoassays improves HIT diagnosis G. Ciarrocca Taranta¹, A. Rogolino², A. Bertelli¹, A. Sorrentino¹, M. Di Gioia², F. Cesari², B. Giusti^1,2, E. Sticchi^1,2, M. Berteotti^1,2, A.M. Gori^1,2, R. Marcucci^1,2 | ¹Department of Experimental and Clinical Medicine, University of Firenze; ²Atherothrombotic Disease Unit, Careggi University Hospital, Firenze, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.205

  566

  PDF: 0
• 

  PO42 | DIFFERENTIAL EXPRESSION OF HEMOSTATIC BIOMARKERS ACROSS CANCER TYPE AND DISEASE STAGE: A PROSPECTIVE ANALYSIS OF 4,292 PATIENTS FROM THE HYPERCAN STUDY P. Gómez-Rosas^1|2|, D. Romeo¹, S. Bolognini¹, C. Ticozzi¹, F. Schieppati¹, A. D’Alessio⁴, R. Labianca⁴, A. Falanga^1|5|6, M. Marchetti^1|5|6 | ¹Hospital Papa Giovanni XXIII, Bergamo, Italy; ²Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, the Netherlands; ³Hospital de Oncologia, Unidad Medica de Alta Especialidad (UMAE), Centro Medico Nacional Siglo XXI, Instituto Mexicano del Seguro Social (IMSS), Mexico City, Mexico; ⁴Fondazione ARTET Onlus, Bergamo, Italy; ⁵ERN EuroBloodNet; ⁶School of Medicine and Surgery, University of Milan Bicocca, Italy; *On Behalf Of The Hypercan Investigators

  Società Italiana di Emostasi e Trombosi

  16-04-2026

  https://doi.org/10.4081/btvb.2026.536

  104

  PDF: 31

• PO06 | Extracellular vesicles profiles in patients with porto-sinusoidal vascular disease S. Toffanin¹, E. Campello¹, A. Zanetto², C. M. Radu¹, E. Pinto², K. Fernande², C. Bulato¹, B. Serena¹, L. Spiezia¹, P. Burra², M. Senzolo², P. Simioni¹ | ¹First Chair of Internal Medicine, Department of Medicine, University Hospital of Padua Medical School, Padua; ²Department of Surgery Oncology and Gastroenterology, Gastroenterology and Multivisceral Transplant Unit, University Hospital of Padua, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.268

  482

  PDF: 0
• 

  Influence of emicizumab on protein C-mediated clotting regulation

  Federica Mancazzo, Antonia Vitulli, Lavinia Dirienzo, Concetta T. Ammollo, Fabrizio Semeraro, Mario Colucci

  25-10-2023

  https://doi.org/10.4081/btvb.2023.89

  2478

  PDF: 363

  Supplementary Material: 97
• 

  OC09 | BLEEDING RISK ASSOCIATED WITH FACTOR XI MONOCLONAL ANTIBODIES IN COMBINATION WITH ASPIRIN IN HEALTHY VOLUNTEERS AND ORTHOPEDIC SURGERY PATIENTS: ANALYSIS FROM RECENT PHASE 1 AND PHASE 2 STUDIES A.P. Kithcart¹, M.E. Burczynski¹, P. Banerjee¹, M. Onisko¹, Y. Wang¹, K. Mohammadi¹, D. Li¹, S. Li¹, J. Ackroyd², B.A. Olenchock¹, D.E. Gutstein¹, J. I. Weitz³ | ¹Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA; ²Clinical Research, Fortrea Clinical Research Unit Ltd, Leeds, UK; ³McMaster University, Hamilton, ON, Canada

  Società Italiana di Emostasi e Trombosi

  16-04-2026

  https://doi.org/10.4081/btvb.2026.492

  109

  PDF: 38

• PO45 | Routine prophylaxis with PD-FX concentrate in severe inherited FX deficiency: a case report S. Linari, L. Pieri, M. Attanasio, F. Salvianti, M. Coppo, E. Grisanti, F. Demartis, R. Fjerza, G. Castaman | Centre for Bleeding Disorders and Coagulation, Azienda Ospedaliera Universitaria Careggi, Firenze, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.308

  491

  PDF: 0

• CO21 | Viscoelastic testing in inherited bleeding disorders: a cross-sectional comparison between viscoelastic coagulation monitoring and rotational thromboelastometry C. Simion, C. Samà, C. Bulato, G. Gottardi, D. Regazzo, E. Campello, P. Simioni | Department of Medicine – DIMED, University of Padua, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.227

  507

  PDF: 0
• 

  Vaccine-induced immune thrombotic thrombocytopenia following ChAdOx1 nCoV-19 vaccine: report of two cases

  Rita Carlotta Santoro, Roberto Minici, Marzia Leotta, Mariapia Falbo, Lucia Concetta Elia, Francesca Leo, Antonella Ierardi, Alessandra Strangio, Simona Prejanò

  23-05-2022

  https://doi.org/10.4081/btvb.2022.23

  4272

  PDF: 0
• 

  Still unmet problems with low molecular weight heparin prophylaxis of venous thromboembolism. An Italian survey

  Stefania Cavazza, Gualtiero Palareti*

  03-10-2025

  https://doi.org/10.4081/btvb.2025.177

  1322

  PDF: 238

  HTML: 93

  Supplementary: 70

• PO18 | Does muscle mass matter? Appendicular lean mass as a determinant of anti-XA activity in elderly patientes B.M. Zanforlini¹, V. Bernardi¹, E. Campello², E.M. Bicego¹, C. Curreri¹, A. Vaticano¹, C. Sartori¹, L. Manfron¹, A. Perencin¹, P. Rollo¹, A. Baruffol¹, L. Ruoso¹, C. Simion², C. Bulato², P. Berto², P. Simioni², G. Sergi¹ | ¹Department of Medicine, Geriatrics Section, University of Padova; ²Haemorrhagic and Thrombotic Diseases Unit, Department of Medicine DIMED, Padova University Hospital, Padova, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.278

  500

  PDF: 0
• 

  The evolving landscape of gene therapy for congenital severe hemophilia: a 2024 state of the art

  Giovanni Di Minno, Gaia Spadarella, Ilenia Lorenza Calcaterra, Giancarlo Castaman, Paolo Simioni, Raimondo De Cristofaro, Cristina Santoro, Flora Peyvandi, Matteo Di Minno

  04-09-2024

  https://doi.org/10.4081/btvb.2024.144

  1635

  PDF: 313

  SUPPLEMENTARY MATERIAL: 158
• 

  PO04 | FIBRIN CLOT SHIELDS PROMOTE CLONAL SELECTION IN CANCER CELLS: PROCOAGULANT ACTIVITY AND SURVIVAL OF CLOT-EMBEDDED CELLS. A NOVEL TUMOR MICROENVIRONMENT MODEL M.A. Baghdadi^1|2, E. Mbemba¹, P. Las Casa¹, P. Van Dreden^1|3, N. Saleem^1|4, J. Fareed⁴, P. Kempaiah⁴, M. Sabbah¹, G. Gerotziafas^1|4 | ¹Sorbonne University, INSERM UMR_S_938, CRSA, Research Department "Cancer, Vessels, Biology and Therapeutics" (CaVITE), Research Group "Cancer-Angiogenesis-Thrombosis and Haemostasis," Thrombosis Center, University Institute of Cancerology, Saint Antoine University Hospital Assistance Publique Hôpitaux de Paris (AP-HP) Paris, France; ²Research Center, King Faisal Specialist Hospital and Research Center, Jeddah, Saudi Arabia; ³Diagnostica Stago, Gennevilliers, France; ⁴Center of Translational Research and Education, Department of Pathology and Laboratory Medicine, Loyola University Stritch School of Medicine, Maywood, Ill., USA

  Società Italiana di Emostasi e Trombosi

  16-04-2026

  https://doi.org/10.4081/btvb.2026.500

  120

  PDF: 31

• PO57 | Direct oral anticoagulant determination in urine samples compared to plasma concentrations in outpatients with atrial fibrillation and obesity A. Pannunzio¹, I.M. Palumbo¹, D. Menichelli¹, V. Cammisotto², V. Castellani³, E. Baldacci⁴, R. Mormile⁴, A. Chistolini⁴, G. Bernardini⁵, N. Porcu¹, D. Pastori², J. Harenberg⁶, F. Violi², P. Pignatelli² | ¹Department of General Surgery, Surgical Specialties and Organ Transplantation Paride Stefanini, Sapienza University of Roma, Italy; ²Department of Clinical Internal, Anesthesiological and Cardiovascular Sciences, Sapienza University of Roma, Italy; ³Department of Translational and Precision Medicine, Sapienza University of Roma, Italy; ⁴Department of Hematology, Oncology and Dermatology, Sapienza University of Roma, Italy; ⁵U.O.S.D. Medicina Rigenerativa DAI, Medicina Diagnostica e Radiologia, Policlinico Umberto 1, Roma, Italy; ⁶Ruprecht Karls University of Heidelberg, Germany

  22-10-2025

  https://doi.org/10.4081/btvb.2025.326

  428

  PDF: 0

• CO34 | Evaluation of emicizumab concentration and thrombin generation in a cohort of severe hemophilia A patients with and without inhibitor A. Taglietti¹, S. Ligia¹, F. Paoletti¹, R. Mormile¹, E. Baldacci², A. Chistolini¹, C. Santoro^1,2 | ¹Hematology, Department of Translational and Precision Medicine, Sapienza University of Roma; ²Hematology, Azienda Ospedaliera Universitaria Policlinico Umberto I, Roma, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.241

  521

  PDF: 0