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  Diagnostic and management practices for inherited fibrinogen disorders: a nationwide survey of Italian Hemophilia Treatment Centers

  Renato Marino, Silvia Linari, Marzia Leotta, Antonio Coppola, Chiara Biasoli, Maria Elisa Mancuso, Flora Peyvandi, Cristina Santoro, Ezio Zanon, Rita Carlotta Santoro

  02-12-2025

  https://doi.org/10.4081/btvb.2025.372

  925

  PDF: 120

  HTML: 129

  Supplementary: 79

  Appendix: 80
• 

  The landscape of rare coagulation factor deficiency management in Italy: a national hemophilia center survey

  Silvia Linari, Renato Marino, Marzia Leotta, Antonio Coppola, Patrizia Di Gregorio, Augusto Bramante Federici, Flora Peyvandi, Cristina Santoro, Ezio Zanon, Rita Carlotta Santoro

  05-11-2025

  https://doi.org/10.4081/btvb.2025.369

  1360

  PDF: 220

  HTML: 135

  Appendix: 120

• CO046 | BLEEDING RISK FACTOR–BASED PHENOTYPES AND THEIR ASSOCIATION WITH MORTALITY AND HEMORRHAGIC OUTCOMES IN ATRIAL FIBRILLATION T. Bucci¹, A.G. Rigutini¹, A. Perrotta¹, A. Moffa¹, C. Seviroli¹, M. Giustozzi², M.C. Vedovati¹, C. Becattini¹ | ¹Internal, Vascular and Emergency Medicine - Stroke Unit, University of Perugia, Perugia, Italy; ²SSD Angiology, San Giovanni Battista Hospital, Foligno, Italy

  Tommaso Bucci

  26-10-2026

  https://doi.org/10.4081/btvb.2026.748

  29

  PDF: 9
• 

  PO61 | RISK FACTORS FOR INTRACRANIAL HEMORRHAGE: AN UMBRELLA REVIEW TO INFORM MACHINE LEARNING PREDICTION MODELS IN GLIOMA PATIENTS RECEIVING ANTICOAGULATION T.A. Adeyemo, S. Greenley, F. Ware, W. Jones, A. Maraveyas, F. Haque | ¹Centre of Excellence for Data Science, Artificial Intelligence and Modelling DAIM, Faculty of Science and Engineering, University of Hull, UK; ²Hull York Medical School, Hull, UK; ³Academic Library Services, University of Hull, UK; ⁴NHS Humber Health Partnership, Hull, UK

  ICTHIC 2026

  16-04-2026

  https://doi.org/10.4081/btvb.2026.552

  531

  PDF: 115

• PO124 | BLEEDING COMPLICATIONS DURING ANTICOAGULATION WITH DOACS FOR NVAF AND THEIR MOST COMMON RISK FACTORS A. delle Femine, P. Di Micco, P. Sommese, M. Di Napoli, A. Di Salvatore, M. Galdiero, A. Lobasso, R. Serpico, V. Brunelli, A. Di Fusco, C. di Gennaro | U.O.C. Medicina Interna, Osp. Santa Maria delle Grazie, Pozzuoli, Italy

  Augusto Delle Femine

  26-10-2026

  https://doi.org/10.4081/btvb.2026.940

  20

  PDF: 6

• PO022 | ARTIFICIAL INTELLIGENCE–ASSISTED PREDICTION OF THROMBOTIC AND HEMORRHAGIC COMPLICATIONS IN PATIENTS TREATED WITH VITAMIN K ANTAGONISTS: A RETROSPECTIVE EXPLORATORY STUDY G. Sottilotta¹, F. Misiti², G. Praticò¹, D. Megalizzi¹, F. Luise³ | ¹UOSD Microcitemie - Emostasi e Trombosi; ³Laboratorio Analisi Grande Ospedale Metropolitano di Reggio Calabria, Italy; ²Associazione Emofilici di Reggio Calabria, Italy

  Gianluca Sottilotta

  26-10-2026

  https://doi.org/10.4081/btvb.2026.838

  31

  PDF: 12

• PO08 | Efficacy and safety of thromboprophylaxis in hospitalized hematological patients: a monocenter retrospective study S. Cordella^1,2, V. Coluccio³, M. Luppi¹, M. Marietta¹ |  ¹Department of Medical and Surgical Sciences, Section of Hematology. University of Modena and Reggio Emilia, Azienda Ospedaliero-Universitaria di Modena; ²Clinical and Experimental Medicine PhD Programme, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena; ³Department of Hematology, Unità Sanitaria Locale di Modena, Italy 

  22-10-2025

  https://doi.org/10.4081/btvb.2025.270

  576

  PDF: 15

• PO110 | CLINICAL OUTCOMES AND SURVIVAL OF UNUSUAL SITE VENOUS THROMBOSIS IN PATIENTS WITH AND WITHOUT MYELOPROLIFERATIVE NEOPLASMS: A RETROSPECTIVE SINGLE-CENTER STUDY I. Bertozzi, M.T. Sartori, G. Libralon, M. Zerbinati, A. Galbiati, P. Simioni | Department of Medicine, University of Padova, Italy

  Irene Bertozzi

  26-10-2026

  https://doi.org/10.4081/btvb.2026.926

  24

  PDF: 9
• 

  Combined oral contraceptives and the risk of venous thromboembolism carriers of antithrombin, protein C or S deficiency: Sub-analysis of a prospective cohort study

  Daniela Tormene, Elena Campello, Chiara Simion, Anna Poretto, Paolo Prandoni, Paolo Simioni

  03-11-2022

  https://doi.org/10.4081/btvb.2022.42

  1584

  PDF: 495

• CO004 | A NOVEL GENETIC CLASSIFICATION OF INHIBITOR RISK FOR F8 NONSENSE MUTATIONS BASED ON IMMUNOGENIC PROFILING OF RIBOSOMAL READTHROUGH M.F. Testa¹, M. Pinotti¹, A. Branchini¹, M.E. Mancuso², F. Bernardi¹, D. Balestra² | ¹Department of Life Sciences and Biotechnology and LTTA Center, University of Ferrara, Ferrara, Italy; ²IRCCS, Humanitas Research Hospital, Center for Thrombosis and Hemorrhagic diseases, Milano, Italy

  Maria Francesca Testa

  26-10-2026

  https://doi.org/10.4081/btvb.2026.706

  33

  PDF: 10
• 

  Rationale and design of a study on D-dimer use to stratify patients after a first unprovoked venous thromboembolism for their risk of recurrence: extended low-dose Apixaban given only to patients with positive D-dimer results The Apidulcis study

  Gualtiero Palareti, Paolo Prandoni, Cristina Legnani, Emilia Antonucci, Serena Zorzi, Alberto Tosetto, Lorenza Bertù, Sophie Testa, Vittorio Pengo, Walter Ageno, Ida Martinelli, Benilde Cosmi, Eugenio Bucherini, Daniela Poli

  22-03-2022

  https://doi.org/10.4081/btvb.2022.10

  1890

  PDF: 564

  APPENDIX: 144

• PO96 | Patient management with arteriovenous thrombotic manifestation and hemorrhagic complications M. Aversano, E. Cimino, L. Jr Valletta, C. Caputo, M. Romeo, M.D. Di Minno, A. Tufano, I.L. Calcaterra, C. De Luca, R. Russo, G. D’errico, P. Conca | Università degli Studi Federico II, Napoli, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.366

  594

  PDF: 14
• 

  Comparison among three different bleeding scores and the thrombin generation assay to assess the different hemorrhagic phenotypes in patients with FVII deficiency

  Samantha Pasca, Cristina Santoro, Chiara Ambaglio, Marisanta Napolitano, Marta Milan, Letizia Natali, Silvia Nannizzi, Filippo Mori, Paolo Simioni, Ezio Zanon

  23-05-2022

  https://doi.org/10.4081/btvb.2022.12

  5660

  PDF: 546
• 

  Association between non-O blood type and early unexplained recurrent spontaneous abortion in women with and without inherited thrombophilia

  Anna Poretto, Elisabetta Borella, Giacomo Turatti, Michelangelo Marobin, Elena Campello, Daniela Tormene, Paolo Simioni, Luca Spiezia

  14-11-2022

  https://doi.org/10.4081/btvb.2022.47

  2951

  PDF: 456
• 

  PO12 | IMPACT OF INHERITED THROMBOPHILIA ON CANCER-ASSOCIATED THROMBOSIS: A SYSTEMATIC REVIEW AND META-ANALYSIS E. Campello¹, G. Furlan¹, A. Boccatonda², A. Napolitano¹, C. Simion¹, P. Simioni¹ | ¹Internal Medicine 1 and Thrombotic and Hemorrhagic Diseases Unit, Department of Medicine, University of Padova, Italy; ²Diagnostic and Therapeutic Interventional Ultrasound Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Policlinico Sant'Orsola-Malpighi, Bologna, Italy

  ICTHIC 2026

  16-04-2026

  https://doi.org/10.4081/btvb.2026.508

  484

  PDF: 111

• PO38 | Rates of hemorrhagic events and hemodialysis circuit thrombosis in patients with end-stage renal disease on hemodialytic treatment receiving a factor-XI inhibitor: a systematic review and meta-analysis D. Santagata, G. Barbui, M.P. Donadini, A. Squizzato | Department of Medicine and Surgery, Research Center on Thromboembolic Disorders and Antithrombotic Therapies, University of Insubria, Varese and Como, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.301

  617

  PDF: 26

• PO077 | BALANCING BLEEDING AND THROMBOSIS: SAFETY OF LOW-MOLECULAR-WEIGHT HEPARIN THROMBOPROPHYLAXIS IN PATIENTS WITH HEMOPHILIA UNDERGOING MAJOR SURGERY S. Bergonzi^1|2|3, G. Murante^1|2|3, M. Capetta^1|2|3, F. Valeri^1|2, C. Dainese^1|2, A. Valpreda^3|4, R. Pastorino^3|4, F. Bocchi^3|4, B. Bruno^2|3, A. Borchiellini^1|2 | ¹Regional Centre for Hemorrhagic and Thrombotic Diseases, AOU Città della Salute e della Scienza, Turin, Italy; ²Division of Hematology, AOU Città della Salute e della Scienza, Università di Torino, Italy; ³Department of Molecular Biotechnology and Health Sciences, University of Turin, Italy; ⁴Central Laboratory Baldi and Riberi, AOU Città della Salute e della Scienza, Università di Torino, Italy

  Sara Bergonzi

  26-10-2026

  https://doi.org/10.4081/btvb.2026.893

  22

  PDF: 7
• 

  PO30 | LONG-TERM ANTICOAGULANT THERAPY AND PREVENTION OF RECURRENT VENOUS THROMBOEMBOLISM IN ADVANCED OVARIAN CANCER V. Bitsadze ¹, A. Vorobev ¹, J. Khizroeva ¹, A. Solopova ¹, M. Tretyakova ¹, N. Gashimova ¹, K. Grigoreva ¹, A. Khisamieva ¹, J. Gris ^1|2, I. Elalamy^1|3|4, G. Gerotziafas^1|3|4, A. Makatsariya¹ | ¹Department of Obstetrics, Gynecology and Perinatal Medicine, N. F. Filatov Clinical Institute of Children’s Health, I. M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia; ²Faculty of Pharmaceutical and Biological Sciences, Montpellier University, France; ³Department Hematology and Thrombosis Center, Medicine Sorbonne University, Paris, France; ⁴Hospital Tenon, Paris, France

  ICTHIC 2026

  16-04-2026

  https://doi.org/10.4081/btvb.2026.525

  473

  PDF: 98

• CO07 | Real word management of anticoagulant therapy in brain metastasis: moving toward a multidisciplinary approach in complex cases E. Lotti¹, C. Manneschi², S. Fancelli², F. Scolari¹, F. Crudele¹, D. Poli¹, M. Berteotti¹, D. Rossini³, S. Pillozzi², L. Antonuzzo^2,3, R. Marcucci^1,3 | ¹Disease Unit, Careggi University Hospital, Firenze; ²Oncology Unit, Careggi University Hospital, Firenze; ³Department of Experimental and Clinical Biomedical Sciences, University of Firenze, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.211

  626

  PDF: 20

• CO-72 | HEREDITARY FACTOR X DEFICIENCY UNMASKED BY NECROTIZING HEMORRHAGIC PANCREATITIS: A CASE REPORT M. Leotta, A. Strangio, A. Ierardi, R.C. Santoro | Hemophilia Treatment Center AOU Dulbecco, Catanzaro, Italy

  Marzia Leotta

  14-10-2026

  https://doi.org/10.4081/btvb.2026.682

  33

  PDF: 16

• CO-76 | MILD HEMOPHILIA A CARRIER WITH CONCOMITANT STORAGE POOL DISEASE: DIAGNOSTIC CHALLENGES IN A SYMPTOMATIC FEMALE PATIENT A. Strangio, M. Leotta. A. Ierardi, R.C. Santoro | Hemophilia center, AOU Renato Dulbecco, Catanzaro, Italy

  Alessandra Strangio

  14-10-2026

  https://doi.org/10.4081/btvb.2026.686

  34

  PDF: 19

• PO92 | Challenging management of portal vein thrombosis in a cirrhotic patient on hormone therapy after breast cancer L. Jr Valletta, C. De Luca, M. Aversano, C. Caputo, E. Cimino, P. Conca, A. Tufano, M.D. Di Minno | AOU Federico II Napoli, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.362

  570

  PDF: 18

• PO012 | RECURRENT CENTRAL RETINAL VEIN THROMBOSIS IN A PATIENT WITH MILD HEMOPHILIA A AND HETEROZYGOSITY FOR THE PROTHROMBIN G20210A VARIANT I. Zatta¹, E. Pacquola¹, L. Di Daniel², C. Simion³, E. Zanon³, P. Simioni³, S. Villalta², L. Abbruzzese¹ | ¹Medicina Trasfusionale Osp. Ca’ Foncello, Treviso, Italy; ²Medicina Generale Osp. S. Giacomo, Castelfranco V.to, Italy; ³Clinica Medica 1° Azienda-Ospedale Università, Padova, Italy

  Enrica Pacquola

  26-10-2026

  https://doi.org/10.4081/btvb.2026.828

  22

  PDF: 9

• CO-24 | BALANCING BLEEDING AND THROMBOSIS: SAFETY OF LOW-MOLECULAR-WEIGHT HEPARIN THROMBOPROPHYLAXIS IN PATIENTS WITH HEMOPHILIA UNDERGOING MAJOR SURGERY S. Bergonzi^1|2|3, G. Murante^1|2|3, M. Capetta^1|2|3, F. Valeri^1|2, C. Dainese^1|2, A. Valpreda^3|4, R. Pastorino^3|4, F. Bocchi^3|4, B. Bruno^2|3, A. Borchiellini^1|2 | ¹Regional Centre for Hemorrhagic and Thrombotic Diseases, AOU Città della Salute e della Scienza, Torino, Italy; ²Division of Hematology, AOU Città della Salute e della Scienza, University of Turin, Italy; ³Department of Molecular Biotechnology and Health Sciences, University of Turin, Italy; ⁴Central Laboratory Baldi and Riberi, AOU Città della Salute e della Scienza, University of Turin, Italy

  Sara Bergonzi

  14-10-2026

  https://doi.org/10.4081/btvb.2026.634

  47

  PDF: 15

• CO27 | Intracerebral hemorrhage in hemophilia A and B: a 10-year prospective multicenter study in Italy (2012–2022) E. Zanon¹, A. Napolitano¹, A. Porreca², F. Demartis³, A. Coppola⁴, C. Santoro⁵, I. Cantori⁶, A. C. Molinari⁷, C. Biasioli⁸, M. Luciani⁹, G. Sottilotta¹⁰, B. Pollio¹¹, A. Borchiellini¹², A. Tosetto¹³, P. Flora¹⁴, P. Simioni¹ | ¹Haemophilia Center, First Chair of Internal Medicine, Department of Medicine, University-Hospital of Padua Medical School, Padua; ²Department of Human Sciences and Promotion of the Quality of Life, Unit of Clinical and Molecular Epidemiology IRCCS San Raffaele Roma Open University, Roma; Unit of Clinical and Molecular Epidemiology IRCCS San Raffaele, Roma; ³Centre for Bleeding Disorders, Careggi University Hospital of Firenze; ⁴Azienda Ospedaliero Universitaria di Parma; ⁵Hematology Division, Umberto I University Hospital of Roma; ⁶Haemophilia Center, Department of Transfusion Medicine, Hospital of Macerata; ⁷IRCCS Istituto Giannina Gaslini, Genova; ⁸Haemophilia and Transfusion Centre, Bufalini Hospital, Cesena; ⁹Children’s Hospital Bambino Gesù, Roma; ¹⁰Haemophilia Center, Department of Onco-Hematology and Radioterapy, Hospital of Reggio Calabria; ¹¹Haemophilia Pediatric Center, Transfusion Medicine, City of Health and Science of Turin; ¹²City of Health and Science of Turin; ¹³Hemorrhagic and Thrombotic Diseases Unit, S. Bortolo Hospital of Vicenza; ¹⁴RCCS Foundation Ca’ Granda Maggiore Policlinico Hospital, Milan, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.233

  692

  PDF: 31

• PO009 | THROMBOPHILIA AND ASSISTED REPRODUCTIVE TECHNOLOGY: PRELIMINARY RESULTS FROM A SINGLE CENTER RETROSPECTIVE COHORT STUDY G. Burrei², E. Malloggi¹, S. Moruzzi¹, L. Delfino¹, F. Pizzolo¹, L. Panepinto¹, F. Presa¹, C. Spillere¹, A. Moschella¹, F. Zoccatelli¹, S. Friso¹, N. Martinelli¹, S. Suardi¹ | ¹Department of Medicine, University Hospital, Verona, Italy; ²General Medicine Unit, Magalini Hospital, Villafranca di Verona, Italy

  Giulia Burrei

  26-10-2026

  https://doi.org/10.4081/btvb.2026.825

  25

  PDF: 9

• CO-54 | DECREASED BONE MINERAL DENSITY IN HEMOPHILIA IS NOT CORRELATED WITH INCREASED RISK OF FRACTURES M.R. Fasulo¹, F. Carrone², G. Mazziotti^3|4, A. Colombo¹, C. Lodigiani¹, M.E. Mancuso^1|4 | ¹Center for Thrombosis and Hemorrhagic Diseases, IRCCS Humanitas Research Hospital, Rozzano, Milano, Italy; ²Endocrinology and Diabetology Unit, Humanitas Mater Domini, Castellanza, Varese, Italy; ³Endocrinology, Diabetology and Medical Andrology Unit, Metabolic Bone Diseases and Osteoporosis Section, IRCCS Humanitas Research Hospital, Rozzano, Milano, Italy; ⁴Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milano, Italy

  Maria Rosaria Fasulo

  14-10-2026

  https://doi.org/10.4081/btvb.2026.664

  38

  PDF: 16

• CO062 | REDUCED-DOSE DOACs IN EXTENDED TREATMENT OF CANCER-ASSOCIATED THROMBOSIS (RED-CAT): INTERIM ANALYSIS FROM A MULTICENTER RETROSPECTIVE OBSERVATIONAL STUDY (COORDINATING CENTER DATA) S. Bergonzi^1|2|3, A. Ghigo⁴, L. Carpisassi⁴, G. Murante^1|2|3, M. Capetta^1|2|3, F. Valeri^1|2, C. Dainese^1|2, A. Valpreda^3|5, R. Pastorino^3|5, F. Bocchi^3|5, A. Porreca^6|7, B. Bruno^2|3, A. Borchiellini^1|2 | ¹Regional Centre for Hemorrhagic and Thrombotic Diseases, AOU Città della Salute e della Scienza, Turin, Italy; ²Division of Hematology, AOU Città della Salute e della Scienza, Università di Torino, Italy; ³Department of Molecular Biotechnology and Health Sciences, University of Turin, Italy; ⁴Division of Internal Medicine, AOU Città della Salute e della Scienza, Università di Torino, Italy; ⁵Central Laboratory Baldi and Riberi, AOU Città della Salute e della Scienza, Università di Torino, Italy; ⁶Department of Human Sciences and Quality of Life Promotion, San Raffaele University, Roma, Italy; ⁷Clinical and Molecular Epidemiology, IRCCS San Raffaele, Roma, Italy

  Sara Bergonzi

  26-10-2026

  https://doi.org/10.4081/btvb.2026.764

  24

  PDF: 10

• CO17 | Clinical relevance of isolated anti-phosphatidylserine/ prothrombin antibody positivity A. Hoxha¹, P. Žigon^2,3, L. Katja^2,3, S. Čučnik^2,4, Ž. Rotar^2,5, S. Gavasso¹, P. Zerbinati¹, G. Gobbo¹, P. Simioni¹ | ¹University of Padua, Internal Medicine Unit, Thrombotic and Hemorrhagic Centre, Department of Medicine-DIMED, Padua, Italy; ²University Medical Centre Ljubljana, Department of Rheumatology, Ljubljana, Slovenia; ³University of Primorska, Faculty of Mathematics, Natural Sciences and Information Technologies, Koper, Slovenia; ⁴University of Ljubljana, Faculty of Pharmacy, Ljubljana, Slovenia; ⁵University of Ljubljana, Faculty of Medicine, Ljubljana, Slovenia

  22-10-2025

  https://doi.org/10.4081/btvb.2025.221

  643

  PDF: 16

• PO070 | INFECTIVE ENDOCARDITIS AND ISCHEMIC CEREBRAL EVENTS IN A PATIENT WITH SYSTEMIC LUPUS ERYTHEMATOSUS AND TRIPLE ANTIPHOSPHOLIPID POSITIVITY: THE ROLE OF ANTICOAGULATION IN PRIMARY PREVENTION T. Marrazzo¹, M.P. Ursi², R. Andini¹, R. Albisinni³ | ¹UOC Med Interna e dei Trapianti; ²UOC Mecau; ³UOC CCH generale, Osp. Monaldi AORN dei Colli, Napoli, Italy

  Tommaso Marrazzo

  26-10-2026

  https://doi.org/10.4081/btvb.2026.886

  25

  PDF: 8

• PO104 | BLEEDING AND THROMBOTIC OUTCOMES DURING EXTENDED DIRECT ORAL ANTICOAGULANT THERAPY: AN EIGHT YEAR RETROSPECTIVE ANALYSIS G. Sottilotta¹, G. Praticò¹, S. Cuzzocrea¹, D. Megalizzi¹, F. Luise² | ¹UOSD Microcitemie - Emostasi e Trombosi. Grande Ospedale Metropolitano di Reggio Calabria, Italy; ²Laboratorio Analisi. Grande Ospedale Metropolitano di Reggio Calabria, Italy

  Gianluca Sottilotta

  26-10-2026

  https://doi.org/10.4081/btvb.2026.920

  28

  PDF: 10

• 29th National Conference of the Italian Society for the Study of Hemostasis and Thrombosis, 2025

  Guest Editor: Valerio De Stefano

  22-10-2025

  https://doi.org/10.4081/btvb.2025.408

  883

• PO150 | FACTOR XII DEFICIENCY IN THE SETTING OF RECURRENT THROMBOSIS AND EXTENDED VENOUS OBSTRUCTION: A CASE ANALYSIS L. Leoni¹, G. Pata¹, A. Domenighini¹, L. Crippa², T. D'aliberti¹, G. Galimberti¹, F. Paciullo¹, P. Rovere Querini¹ | ¹Internal Medicine Unit; ²Coagulation Service Thrombosis Research Unit, IRCCS San Raffaele Scientific Institute, Milano, Italy

  Laura Leoni

  26-10-2026

  https://doi.org/10.4081/btvb.2026.966

  21

  PDF: 7

• CO-67 | CONGENITAL DYSFIBRINOGENEMIA: BLEEDING PHENOTYPE, THROMBOTIC COMPLICATIONS, AND LONG-TERM MANAGEMENT IN A MULTICENTER COHORT M. Biglietto^1|2, M. Presti¹, R.C. Santoro³, I. Nichele⁴, M. Napolitano⁵, S. Pasca⁶, A. Borchiellini⁷, B. Pollio⁸, E. Zanon⁹, G. Barillari¹⁰, A. Poz¹⁰, S. Sorella¹, S. Ligia¹, R. Mormile¹, E. Baldacci¹, G. Castaman¹¹, F. Peyvandi^12|13, C. Santoro¹ | ¹Hematology, Department of Translational and Precision Medicine, Sapienza University of Rome, Italy; ²Department of Molecular Biology, Sapienza University of Rome, Italy; ³Hemostasis and Thrombosis Unit, Azienda Ospedaliera Pugliese-Ciaccio, Catanzaro, Italy; ⁴Hematology Unit, Azienda ULSS 8 Berica - San Bortolo Hospital, Vicenza, Italy; ⁵Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, University of Palermo, Italy; ⁶Coagulation Diseases Center, Transfusion Medicine Department - Azienda Sanitaria Universitaria Integrata del Trentino, Trento, Italy; ⁷Centro di Riferimento Regionale Malattie Emorragiche e Trombotiche dell'Adulto, Divisione di Ematologia, Università Città della Salute e della Scienza di Torino, Italy; ⁸SIMT Immunohematology and Transfusion Medicine Service, Diagnostic Department, A.O. Città della Salute e della Scienza, Torino, Italy; ⁹Department of Medicine, Haemophilia Centre, University Hospital of Padua, Italy; ¹⁰Center for Hemorrhagic and Thrombotic Diseases, General and University Hospital S. Maria della Misericordia, Udine, Italy; ¹¹Centre for Bleeding Disorders and Coagulation, Careggi University Hospital, Firenze, Italy; ¹²IRCCS Fondazione Ca' Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Milano, Italy; ¹³Università degli Studi di Milano, Department of Pathophysiology and Transplantation, Milano, Italy

  Mario Biglietto

  14-10-2026

  https://doi.org/10.4081/btvb.2026.677

  46

  PDF: 13

• BEST-09 | IMMUNOGENIC IMPLICATIONS OF TRANSLATIONAL READTHROUGH MODULATE THE ASSOCIATION OF F8 NONSENSE MUTATIONS WITH INHIBITORS IN HEMOPHILIA A D. Balestra¹, M.F. Testa¹, M. Pinotti¹, A. Branchini¹, M.E. Mancuso², F. Bernardi¹ | ¹Department of Life Sciences and Biotechnology and LTTA Center, University of Ferrara, Italy; ²IRCCS, Humanitas Research Hospital, Center for Thrombosis and Hemorrhagic diseases, Milano, Italy

  Dario Balestra

  14-10-2026

  https://doi.org/10.4081/btvb.2026.609

  80

  PDF: 16

• CO-83 | ACQUIRED FACTOR V DEFICIENCY IN A HIGH-THROMBOTIC-RISK PATIENT: DIAGNOSTIC DILEMMA AND SUCCESSFUL MANAGEMENT G. Gazzelli¹, L. Banov¹, Y. Azzanelli¹, C. Vernarecci¹, F. Marotta¹, F. Giacopelli¹, E. Cenni², V. Agostini², A.C. Molinari¹ | ¹IRCCS Istituto Giannina Gaslini, Italy; ²IRCSS AOM S. Martino, Genova, Italy

  Angelo Claudio Molinari

  14-10-2026

  https://doi.org/10.4081/btvb.2026.693

  53

  PDF: 22

• CO012 | LONG-TERM RISK OF RECURRENT VENOUS THROMBOEMBOLISM IN ADULT PATIENTS WITH ACTIVE CANCER AND FIRST CATHETER-RELATED UPPER EXTREMITY DEEP VEIN THROMBOSIS AFTER DISCONTINUATION OF ANTICOAGULANT TREATMENTS AND LINE REMOVAL: A RETROSPECTIVE MULTI-CENTER COHORT STUDY – CANCER-CRT STUDY L. Girardi^1|2, W. Ageno³, L. Bertù¹, C. Lodigiani⁴, L.A. Ciuffini⁴, M.C. Vedovati⁵, C. Becattini⁵, A. Sammarco⁶, G. Camporese⁶, G. Cuni^1|7, C. Ambaglio⁷, M.P. Donadini¹ | ¹Research Center on Thromboembolic Diseases and Antithrombotic Treatment, Department of Medicine and Surgery, University of Insubria, Varese, Italy; ²Department of Medicine, The Ottawa Hospital Research Institute, University of Ottawa, Ontario, Canada; ³Department of Medicine, University of Padua, Padova, Italy; ⁴Center for Thrombosis and Hemorrhagic Diseases, IRCCS Humanitas Research Hospital, Rozzano, Milano, Italy; ⁵Internal and Cardiovascular Medicine-Stroke Unit, University of Perugia, Perugia, Italy; ⁶Clinica Medica 1, Department of Medicine, DIMED, Padova University Hospital, Padova, Italy; ⁷Immunohematology and Transfusion Medicine, Department of Transfusion Medicine and Hematology, ASST Papa Giovanni XXIII, Bergamo, Italy

  Laura Girardi

  26-10-2026

  https://doi.org/10.4081/btvb.2026.714

  35

  PDF: 9

• PO09 | Comparison of different aggregometry methods for evaluation of platelet function in patients with myeloproliferative neoplasms C. Fortino, I. Bertozzi, D. Regazzo, L. Gianesello, G. Nuozzi, F. Sartorello, V. Azzaro, G. Saggiorato, A. Bertomoro, P. Simioni | First Medical Clinic, Department of Medicine – DIMED, Università degli Studi di Padova, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.271

  557

  PDF: 12

• PO091 | RESPONSE AND CARDIOVASCULAR SAFETY OF FOSTAMATINIB IN CHRONIC IMMUNE THROMBOCYTOPENIA: A REAL WORLD ANALYSIS C. Giubbilei, G. Giustini, A. Baffioni, V. Carrai | SOD Ematologia, Azienda Universitaria Ospedaliera Careggi, Firenze, Italy

  Cristina Giubbilei

  26-10-2026

  https://doi.org/10.4081/btvb.2026.907

  21

  PDF: 7
• 

  The von Willebrand factor-ADAMTS-13 axis: a two-faced Janus in bleeding and thrombosis

  Stefano Lancellotti, Monica Sacco, Maira Tardugno, Antonietta Ferretti, Raimondo De Cristofaro

  26-04-2022

  https://doi.org/10.4081/btvb.2022.11

  2653

  PDF: 630

• CO044 | QUALITY AND SAFETY OF VITAMIN K ANTAGONIST TREATMENT IN PEDIATRIC PATIENTS: A RETROSPECTIVE CLINICAL AUDIT FROM A SINGLE CENTER C. Ambaglio¹, T. Zollner¹, G. Cuni¹, S. Bolognini¹, C. Ticozzi¹, F. Schieppati¹, E. Galimberti¹, O.C. Cretu¹, V. Brusegan¹, F. Zunino¹, F. Duca², M. Marchetti¹, A. Falanga^1|2, L. Barcella¹ | ¹Immunohematology and Transfusion Medicine, Department of Transfusion Medicine and Hematology, ERN-EuroBloodNet - European Reference Network in Rare Hematological Diseases, ASST Papa Giovanni XXIII, Bergamo, Italy; ²School of Medicine and Surgery, University of Milano-Bicocca, Milano, Italy

  Chiara Ambaglio

  26-10-2026

  https://doi.org/10.4081/btvb.2026.746

  23

  PDF: 9

• PO84 | Beyond the scores: unmasking a silent pulmonary embolism in essential thrombocythemia N. Battino | ASL Sulcis Iglesiente PO CTO, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.353

  648

  PDF: 13

• CO-22 | CLINICAL FEATURES IN PATIENTS WITH NON-SEVERE HEMOPHILIA A: THE DISCOVERY SCORE PROPOSAL FOR PROPHYLAXIS PRESCRIPTION M.N.D. Di Minno¹, E. Baldacci², C. Biasoli³, A. Borchiellini⁴, F. Daniele⁵, P. Di Gregorio⁶, C. Gorio⁷, G. Malcangi⁸, E. Marchesini⁹, I. Ricca¹⁰, R. Santoro¹¹, S. Siragusa¹², M.R. Villa¹³, E. Zanon¹⁴, A. Tagliaferri¹⁵, A. Coppola¹⁵ | ¹Hub Centre for Thrombotic and Hemorrhagic Disorders, Federico II University Hospital, Napoli, Italy; ²Haematology, University Hospital Policlinico Umberto I, Roma, Italy; ³Interdepartmental Simple Structure for the Management of Hemorrhagic and Thromboembolic Diseases, M. Bufalini Hospital, Cesena, Italy; ⁴Regional Centre for Hemorrhagic and Thrombotic Diseases, AOU Città della Salute e della Scienza, Torino, Italy; ⁵Haemostasis and Thrombosis Service, Ospedale Civile dell'Annunziata, Cosenza, Italy; ⁶Transfusion Medicine Department, "SS. Annunziata" Hospital, Chieti, Italy; ⁷Pediatric Onco-Hematology Unit, Children's Hospital, ASST-Spedali Civili, Brescia, Italy; ⁸Haemophilia and Thrombosis Center, University Hospital Policlinico-Giovanni XXIII, Bari, Italy; ⁹Hemophilia Centre, SC Vascular and Emergency Department, University of Perugia, Italy; ¹⁰Centro Emofilia, Città della Salute e della Scienza, Torino, Italy; ¹¹Hemostasis and Thrombosis Unit, Azienda Ospedaliero Universitaria Dulbecco, Catanzaro, Italy; ¹²Centro di Riferimento Regionale per le Emocoagulopatie Congenite, Palermo, Italy; ¹³Hematology Unit, Ospedale Santa Maria di Loreto, Napoli, Italy; ¹⁴Hemophilia and Thrombosis Center, University Hospital of Padua, Italy; ¹⁵Hemophilia and Thrombosis Center, Azienda Ospedaliera di Parma, Italy

  Matteo Di Minno

  14-10-2026

  https://doi.org/10.4081/btvb.2026.632

  55

  PDF: 15
• 

  The evolving landscape of gene therapy for congenital severe hemophilia: a 2024 state of the art

  Giovanni Di Minno, Gaia Spadarella, Ilenia Lorenza Calcaterra, Giancarlo Castaman, Paolo Simioni, Raimondo De Cristofaro, Cristina Santoro, Flora Peyvandi, Matteo Di Minno

  04-09-2024

  https://doi.org/10.4081/btvb.2024.144

  2089

  PDF: 359

  SUPPLEMENTARY MATERIAL: 218

• PO108 | DIRECT ORAL ANTICOAGULANTS IN PATIENTS WITH VENOUS THROMBOEMBOLISM RECEIVING LONG-TERM IMMUNOSUPPRESSIVE THERAPY AFTER LIVER AND KIDNEY TRANSPLANTATION: A SINGLE-CENTER EXPERIENCE U. Mazzarelli¹, L. Agrelli¹, A. Cirillo¹, C. Crescenzo², M. Triggiani¹, A. Guida³ | ¹Dipartimento di Medicina Interna, Università degli studi di Salerno, Italy; ²UOC Nefrologia e Trapianti di rene; ³Centro per le malattie emorragiche congenite e malattie trombotiche, AOU San Giovanni di Dio e Ruggi d'Aragona Salerno, Italy

  Anna Guida

  26-10-2026

  https://doi.org/10.4081/btvb.2026.924

  29

  PDF: 9

• CO107 | PREGNANCY IN A YOUNG WOMAN WITH SEVERE THROMBOCYTOPENIA ASSOCIATED WITH GNE GENE MUTATION S. Bonafini¹, A. Meneguzzi¹, A. Savoia², S. Uccella³, V. Tamborrino³, S. Cesaro³, E. Bonetti³, A. Giuffrida⁴, P. Minuz¹, C. Fava¹ | ¹Dip. Medicina, Azienda Ospedaliera Universitaria Integrata Verona, Italy; ²Dip di Ingegneria per la Medicina di innovazione, Università di Verona, Italy; ³Dip. Materno-Infantile, Azienda Ospedaliera Universitaria Integrata Verona, Italy; ⁴Dip. Medicina trasfusionale, Azienda Ospedaliera Universitaria Integrata Verona, Italy

  Sara Bonafini

  26-10-2026

  https://doi.org/10.4081/btvb.2026.809

  25

  PDF: 9
• 

  Personalized bleeding risk assessment for atrial fibrillation patients on direct oral anticoagulants: the DOAC score

  Paolo Prandoni

  11-10-2023

  https://doi.org/10.4081/btvb.2023.97

  2135

  PDF: 467

• PO102 | EFFICACY AND SAFETY OF VISCOELASTIC TESTING–GUIDED TRANSFUSION IN CIRRHOSIS UNDERGOING INVASIVE PROCEDURES: A META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS A. Boccatonda¹, E. Campello², A. Napolitano², C. Simion², C. Serra¹, P. Simioni² | ¹Diagnostic and Therapeutic Interventional Ultrasound Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Policlinico Sant'Orsola-Malpighi, Via Massarenti N 9, 40138, Bologna, Italy; ²First Chiar of Internal Medicine and Thrombotic and Hemorrhagic Diseases Unit, Department of Medicine, University Hospital of Padova, 35128, Padova, Italy

  Andrea Boccatonda

  26-10-2026

  https://doi.org/10.4081/btvb.2026.918

  20

  PDF: 8

• PO132 | POST KIDNEY TRANSPLANT PRESENTATION OF ACQUIRED THROMBOTIC THROMBOCYTOPENIC PURPURA: A CASE OF PRE-EXISTING ADAMTS13 INHIBITORS G. Murante^1|2|5, S. Bergonzi^1|2|5, M. Capetta^1|2|5, F. Valeri^1|2, C. Dainese^1|2, A. Valpreda⁴, R. Pastorino^1|5, F. Bocchi^1|5, L. Biancone³, E. Gallo³, B. Bruno^2|5, A. Borchiellini^1|2 | ¹Regional Centre for Hemorrhagic and Thrombotic Diseases; ²Division of Hematology; ³Nephrology Dialysis and Transplant U; ⁴Central Lab. Baldi and Riberi, AOU Città della Salute e della Scienza di Torino, Italy; ⁵Dep. of Molecular Biotechnology and Health Sciences, University of Turin, Italy

  Giovanni Murante

  26-10-2026

  https://doi.org/10.4081/btvb.2026.948

  25

  PDF: 7

• PO02 | Pregnancy and delivery in women with hemophilia and carriers are still challenging: a ten years analysis from The Italian Association of Hemophilia Centers (AICE) M. Napolitano¹, M. Mattana², C. Cammarata¹, M. Leotta³, S. Linari⁴, M.E. Mancuso⁵, G. F. Rivolta⁶, C. Santoro⁷, L. Valdrè⁸, R.C. Santoro³, S. Siragusa¹ | ¹Department of Health Promotion, Mother and Child Care, Internal Medicine and Med, Palermo; University of Palermo, Italy; ²Department of Precision Medicine in Medical, Surgical and Critical Care “Me. Pre. Cc”, University of Palermo; ³Hemostasis and Thrombosis Unit, Azienda Ospedaliera Universitaria Dulbecco, Catanzaro; ⁴Center for Bleeding Disorders, Careggi University Hospital, Firenze; ⁵Center for Thrombosis and Hemorrhagic Diseases, IRCCS Humanitas Research Hospital, Rozzano, Milan; ⁶Regional Reference Center for the Treatment of Congenital Hemorrhagic Diseases, Parma University Hospital, Parma; ⁷Hematology, University Hospital Policlinico Umberto I, Roma; ⁸Inherited Bleeding Disorders Unit, IRCCS AOUBO, Bologna, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.312

  698

  PDF: 19

• CO066 | COAGULOPATHY IN CAR-T CELL-TREATED PATIENTS WITH LYMPHOPROLIFERATIVE DISORDERS: A RETROSPECTIVE, SINGLE-CENTER OBSERVATIONAL STUDY I. Santo¹, R. Morganti², G. Leoni³, G. Tancredi³, L. Contino⁴, S. Galimberti³, R.M. Santi⁴, E. Orciuolo⁵ | ¹Azienda Toscana Nord Ovest, Versilia Hospital, Italy; ²Hematology Division AOUP, Pisa, Italy; ³University of Pisa, Hematology Pisa, Italy; ⁴Azienda Ospedaliera Universitaria Alessandria, Italy; ⁵Azienda Ospedaliera Universitaria Pisana, Hematology Pisa, Italy

  Ignazio Santo

  26-10-2026

  https://doi.org/10.4081/btvb.2026.768

  31

  PDF: 9

• CO-70 | CONGENITAL AFIBRINOGENEMIA: BLEEDING PHENOTYPE, THROMBOTIC COMPLICATIONS, AND LONG-TERM MANAGEMENT IN A MULTICENTER COHORT M. Biglietto^1|2, M. Presti¹, R.C. Santoro³, I. Nichele⁴, M. Napolitano⁵, S. Pasca⁶, A. Borchiellini⁷, B. Pollio⁸, E. Zanon⁹, G. Barillari¹⁰, A. Poz¹⁰, S. Sorella¹, S. Ligia¹, R. Mormile¹, E. Baldacci¹, G. Castaman¹¹, F. Peyvandi^12|13, C. Santoro¹ | ¹Hematology, Department of Translational and Precision Medicine, Sapienza University of Rome, Italy; ²Department of Molecular Biology, Sapienza University of Rome, Italy; ³Hemostasis and Thrombosis Unit, Azienda Ospedaliera Pugliese-Ciaccio, Catanzaro, Italy; ⁴Hematology Unit, Azienda ULSS 8 Berica - San Bortolo Hospital, Vicenza, Italy; ⁵Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, University of Palermo, Italy; ⁶Coagulation Diseases Center, Transfusion Medicine Department - Azienda Sanitaria Universitaria Integrata del Trentino, Trento, Italy; ⁷Centro di Riferimento Regionale Malattie Emorragiche e Trombotiche dell'Adulto, Divisione di Ematologia, Università Città della Salute e della Scienza di Torino, Italy; ⁸SIMT Immunohematology and Transfusion Medicine Service, Diagnostic Department, A.O. Città della Salute e della Scienza, Torino, Italy; ⁹Department of Medicine, Haemophilia Centre, University Hospital of Padua, Italy; ¹⁰Center for Hemorrhagic and Thrombotic Diseases, General and University Hospital S. Maria della Misericordia, Udine, Italy; ¹¹Centre for Bleeding Disorders and Coagulation, Careggi University Hospital, Firenze, Italy; ¹²IRCCS Fondazione Ca' Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Milano, Italy; ¹³Università degli Studi di Milano, Department of Pathophysiology and Transplantation, Milano, Italy

  Mario Biglietto

  14-10-2026

  https://doi.org/10.4081/btvb.2026.680

  43

  PDF: 16

• CO-87 | SPONTANEOUS HEMATOMA IN A PATIENT WITH POLYCYTHEMIA VERA: A CASE OF ACQUIRED VON WILLEBRAND DISEASE? A. Strangio, A. Ierardi, M. Leotta, R.C. Santoro | Hemophilia center, AOU Renato Dulbecco, Catanzaro, Italy

  Alessandra Strangio

  14-10-2026

  https://doi.org/10.4081/btvb.2026.697

  50

  PDF: 17
• 

  Persistence of functional anti-PF4 antibodies and neutrophil activation in vaccine-induced immune thrombotic thrombocytopenia

  Eleonora Petito, Anna Maria Mezzasoma, Emanuela Falcinelli, Chiara Conti, Erica De Candia, Raimondo De Cristofaro, Silvia Sorrentino, Gian Marco Podda, Mariangela Scavone, Anna Falanga, Marina Marchetti, Luca Barcella, Stefania Basili, Lucia Stefanini, Andrea Boccatonda, Laura Contino, Patrizia Sciancalepore, Igor Florio, Egidio Imbalzano, Rossella Marcucci, Angela Rogolino, Patrizia Noris, Marta Panella, Rita Santoro, Maria Costanza Turi, Gaetano Vaudo, Rosa Curcio, Paolo Gresele

  18-11-2025

  https://doi.org/10.4081/btvb.2025.400

  967

  PDF: 178

  HTML: 206

• PO64 | A silent hemorrhage in the immuno-thrombotic chaos of antiphospholipid syndrome G. Autiero, S.A. Malerba, A. Malaguti, M. Dalla Vestra, F. Presotto | Medicina Generale, Ospedale dell’Angelo, Mestre-Venezia, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.333

  660

  PDF: 16

• CO28 | Cognitive, adaptive abilities and behavioral symptoms in children and adolescents with hemophilia: a pilot study R. Vallone¹, M. Luciani², A. Smigliani², M. F. Mansueto³, S. Vicari^1,4, D. Menghini¹ | ¹Child and Adolescent Neuropsychiatry Unit, Bambino Gesù Children’s Hospital, IRCCS, Roma; ²OncoHematology Unit, Bambino Gesù Children’s Hospital, IRCCS, Roma; ³Department of Oncology U.O. Hematology AUO Policlinico, Paolo Giaccone, Palermo; ⁴Department of Life Science and Public Health, Università Cattolica del Sacro Cuore, Roma, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.234

  675

  PDF: 22

• PO149 | MANAGEMENT OF ANTITHROMBOTIC THERAPY IN A PATIENT WITH HEMOPHILIA C AND ATRIAL FIBRILLATION E. Marrone¹, G. Ruggiero², E. Cimino³, P. Conca³, C. Miele⁴, F. Gallucci¹, A. Abate¹, C. Romano¹, D. Leosco², U. Valentino¹ | ¹Department of Medicine 3, Cardarelli Hospital, Napoli, Italy; ²School of Specialization in Geriatrics; ³Department of Internal Medicine and Blood Coagulation; ⁴Department of Laboratory Medicine and Transfusion, Federico II University, Napoli, Italy

  Emiliana Marrone

  26-10-2026

  https://doi.org/10.4081/btvb.2026.965

  24

  PDF: 8
• 

  PO26 | OUTCOMES OF DIRECT ORAL ANTICOAGULANTS IN UNUSUAL-SITE THROMBOSIS: IMPACT OF ACTIVE CANCER S. Guglielmo¹, M. Lovisotto¹, L. Scarano¹, E. De Bon², S. Barbar² | ¹Internal Medicine, Department of Medicine, Azienda Ulss 6 Euganea, Cittadella (PD), Italy; ²Thrombotic and Hemorrhagic Disorders Unit, Department of Medicine, Azienda Ulss 6 Euganea, Cittadella (PD), Italy

  ICTHIC 2026

  16-04-2026

  https://doi.org/10.4081/btvb.2026.521

  517

  PDF: 109

• PO91 | Disseminated intravascular coagulation with deep vein thrombosis in a frail patient: an extreme manifestation triggered by sepsis during SGLT2i therapy M. Vacca¹, M.V. Cherchi¹, S. Che¹, G.A.M.L. Costanzo², D. Firinu², M. Mantega¹, S. Del Giacco² | ¹Ospedale Sirai, ASL Sulcis, ²Università degli Studi di Cagliari, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.361

  803

  PDF: 19

• CO20 | Coagulation alterations as prognostic indicators in septic patients L. Baratti¹, S. N. Pasturenzi¹, P. Onorato², W. Ageno³, F. Cortellaro², M.P. Donadini^2,4 | ¹Scuola di Medicina, Università degli Studi dell’Insubria, Varese; ²Pronto Soccorso e Medicina d’Urgenza, Ospedale di Circolo, Varese; ³Dipartimento di Medicina, Università degli Studi di Padova; ⁴Dipartimento di Medicina e Chirurgia, Università degli Studi dell’Insubria, Varese, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.226

  643

  PDF: 17

• PO65 | Utilization of emicizumab in acquired hemophilia A: a case report C. Caputo, P. Conca, I.L. Calcaterra, E. Cimino, M. Romeo, M. Aversano, E. Franco, C. De Luca, G. D’errico, L. Jr Valletta, M. Di Minno, A. Tufano | Department of Clinical Medicine and Surgery, Federico II University, Naples, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.334

  628

  PDF: 26
• 

  Bleeding and thrombosis in patients receiving chimeric antigen receptor T-cell therapy

  Dana Lee, Pedro Luiz Lage Bodour Danielian, Avi Leader

  16-04-2026

  https://doi.org/10.4081/btvb.2026.461

  586

  PDF: 192
• 

  Anticoagulation challenges in patients with hematological malignancy-associated thrombosis and severe thrombocytopenia

  Emilie Chalayer, Géraldine Poenou, Corinne Frere

  16-04-2026

  https://doi.org/10.4081/btvb.2026.429

  389

  PDF: 172

• CO-32 | TRAUMA MANAGEMENT IN SEVERE HEMOPHILIA A: A CASE REPORT J. Di Paolo, R. Malizia, M. Luongo, P. Massaro, M. Di Mascio, S. Verna | Immunohematology Service, ASL 02 Abruzzo, Chieti, Italy

  Josephine Di Paolo

  14-10-2026

  https://doi.org/10.4081/btvb.2026.642

  38

  PDF: 14

• CO36 | Inhibitor titer at diagnosis and clinical course in acquired hemophilia A: a single-center experience C. Simion, B. Stocco, E. Dalla Porta, E. Campello, G. Furlan, L. Spiezia, G. Saggiorato, F. Sartorello, E. Zanon, P. Simioni | Department of Medicine – DIMED, University of Padua, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.243

  588

  PDF: 33

• CO29 | Emergency room physicians and oral anticoagulants related bleeding D. Barcellona^1,2, G. Melis¹, A. Bussu¹, M. Orrù¹, Ml. Caddeo¹, E. Antonucci², A. Mameli¹, F. Marongiu^1,2 | ¹SSD Emostasi e Trombosi, AOU Cagliari; ²Fondazione Arianna, Bologna, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.235

  666

  PDF: 21
• 

  Safety of COVID-19 mRNA vaccination in patients with history of acquired hemophilia A: a case series

  Luca Puccetti, Vincenzo Sammartano, Federico Caroni, Margherita Malchiodi, Paola Calzoni, Eleonora Franceschini, Lucrezia Galasso, Monica Bocchia

  17-10-2022

  https://doi.org/10.4081/btvb.2022.40

  3064

  PDF: 434

• CO34 | Evaluation of emicizumab concentration and thrombin generation in a cohort of severe hemophilia A patients with and without inhibitor A. Taglietti¹, S. Ligia¹, F. Paoletti¹, R. Mormile¹, E. Baldacci², A. Chistolini¹, C. Santoro^1,2 | ¹Hematology, Department of Translational and Precision Medicine, Sapienza University of Roma; ²Hematology, Azienda Ospedaliera Universitaria Policlinico Umberto I, Roma, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.241

  676

  PDF: 12

• PO067 | LONG‑TERM SAFETY AND EFFECTIVENESS OF VITAMIN K ANTAGONISTS IN PATIENTS WITH ANTIPHOSPHOLIPID ANTIBODIES: A RETROSPECTIVE COHORT ANALYSIS G. Sottilotta¹, G. Praticò¹, D. Megalizzi¹, F. Luise² | ¹UOSD Centro per le Microcitemie - Servizio Emostasi e Trombosi; ²Laboratorio Analisi, Grande Ospedale Metropolitano di Reggio Calabria, Italy

  Gianluca Sottilotta

  26-10-2026

  https://doi.org/10.4081/btvb.2026.883

  23

  PDF: 11

• PO099 | CORRELATION BETWEEN DIRECT ORAL ANTICOAGULANTS PLASMA LEVELS AND BRAIN VASCULAR EVENTS L. Riva¹, M. Paolucci², S. Forlivesi², M. Gentile², G. Casella¹, A. Zini², R. Marcucci³ | ¹UOC Cardiologia Ospedale Maggiore AUSL Bologna, Italy; ²IRCCS Istituto delle Scienze Neurologiche di Bologna UOC Neurologia e Rete Stroke metropolitana Ospedale Maggiore AUSL Bologna, Italy; ³SOD Malattie Aterotrombotiche AOU Careggi Università degli Studi di Firenze, Italy

  Letizia Riva

  26-10-2026

  https://doi.org/10.4081/btvb.2026.915

  23

  PDF: 9

• PO89 | Apixaban for secondary prevention of venous thromboembolism in hemodialysis patients: pharmacokinetic profile and safety outcomes S. Guglielmo¹, E. De Bon², L. Scarano¹, R. Fabris¹, E. Pierobon³, S. Barbar² | ¹Internal Medicine, Department of Medicine; ²Thrombotic and Hemorrhagic Disorders Unit, Department of Medicine; ³Nephrology and Dialysis Unit, Azienda ULSS 6 Euganea, Cittadella and Camposampiero, Padua, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.359

  854

  PDF: 15

• CO37 | Assessment of clotting factor activity and sterility in thawed fresh frozen plasma supplied to helicopter emergency medical services for prehospital transfusion D. Romeo¹, M. Marchetti^1,2, M. Testa¹, A. Motta¹, P. Gomez-Rosas¹, G. Ravasio¹, F. Daminelli³, L. Barcella¹, A. Falanga^1,2 | ¹Immunohematology and Transfusion Medicine Department, Hospital Papa Giovanni XXIII, Bergamo; ²School of Medicine and Surgery, University Milano Bicocca, Milan; ³Anesthesia and Resuscitation Department, Hospital Papa Giovanni XXIII, Bergamo, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.244

  685

  PDF: 18

• PO057 | IS PLATELET FUNCTION TESTING CLINICALLY USEFUL IN PATIENTS WITH CHRONIC SUBDURAL HEMATOMA UNDERGOING NEUROSURGERY WHILE ON ANTIPLATELET THERAPY? G. Ciarrocca Taranta¹, G. Pansini², S. Orlandini², O. Para³, M. Di Gioia⁴, A. Rogolino⁴, G. Barbieri¹, R. Marcucci^1|4, A. Della Puppa² | ¹Dep of Experimental and Clinical Medicine, University of Florence, Italy; ²Neurosurgical Dep, Careggi University Hospital, Firenze, Italy; ³Internal Medicine 1 Careggi University Hospital, Firenze, Italy; ⁴Atherothrombotic Diseases, Careggi University Hospital, Firenze, Italy

  Giulia Ciarrocca Taranta

  26-10-2026

  https://doi.org/10.4081/btvb.2026.873

  21

  PDF: 8
• 

  Antithrombotic therapy in idiopathic infertility

  Fabio Tumminello, Silvia Cardi, Corrado Lodigiani, Maria Elisa Mancuso

  03-10-2024

  https://doi.org/10.4081/btvb.2024.126

  3542

  PDF: 1263

• PO130 | HEMORRHAGIC AND THROMBOTIC COMPLICATIONS DURING DOACS TREATMENT: THE IMPORTANCE OF A REGULAR AND PROLONGED FOLLOW-UP D. Barcellona^1|2, A. Mameli², S. Cornacchini², P. Schirru², L. Fenu², V. Casu², F. Marongiu^1|2 | ¹University of Cagliari, Italy; ²Haemostasis and Thrombosis Unit, Azienda Ospedaliero-Universitaria di Cagliari, Italy

  Doris Barcellona

  26-10-2026

  https://doi.org/10.4081/btvb.2026.946

  32

  PDF: 6

• PO53 | Effectiveness and safety of DOACS in patients with renal transplantation A. Ierardi, A. Strangio, M. Leotta, R C. Santoro | UO Emofilia, Emostasi e Trombosi, AOU Renato Dulbecco, Catanzaro, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.322

  647

  PDF: 17

• PO087 | BEYOND POSITIVITY: THE HIERARCHICAL ROLE OF IMMUNOASSAYS IN HEPARIN INDUCED THROMBOCYTOPENIA G. Murante^1|2|3, S. Bergonzi^1|2|3, M. Capetta^1|2|3, F. Valeri^1|2, C. Dainese^1|2, A. Valpreda⁴, R. Pastorino^1|3, F. Bocchi^1|3, A. Porreca⁵, B. Bruno^2|3, A. Borchiellini^1|2 | ¹Regional Centre for Hemorrhagic and Thrombotic Diseases, AOU Città della Salute e della Scienza di Torino, Italy; ²Division of Hematology, AOU Città della Salute e della Scienza, Università di Torino, Italy; ³Dep. of Molecular Biotechnology and Health Sciences, University of Turin, Italy; ⁴Central Lab. Baldi and Riberi, AOU Città della Salute e della Scienza di Torino, Italy; ⁵Dep. of Human Sciences and Quality of Life Promotion, Clinical and Molecular Epidemiology, IRCCS San Raffaele Roma, Italy

  Giovanni Murante

  26-10-2026

  https://doi.org/10.4081/btvb.2026.903

  22

  PDF: 8

• CO043 | LONG TERM TREATMENT WITH VITAMIN K ANTAGONIST IN PEDIATRIC PATIENTS WITH PROSTHETIC HEART VALVE: THE BERGAMO EXPERIENCE T. Zollner¹, C. Ambaglio¹, F. Duca², G. Cuni¹, E. Galimberti¹, O.C. Cretu¹, F. Schieppati¹, F. Zunino¹, V. Brusegan¹, M. Marchetti¹, A. Falanga^1|2, L. Barcella¹ | ¹Immunohematology and Transfusion Medicine, Department of Transfusion Medicine and Hematology, ERN-EuroBloodNet - European Reference Network in Rare Hematological Diseases, ASST Papa Giovanni XXIII, Bergamo, Italy; ²School of Medicine and Surgery, University of Milano-Bicocca, Milano, Italy

  Chiara Ambaglio

  26-10-2026

  https://doi.org/10.4081/btvb.2026.745

  24

  PDF: 9

• PO053 | PLATELET AGGREGATION AND THROMBIN GENERATION IN MULTIPLE MYELOMA: A PROSPECTIVE STUDY M. Biglietto, M. Mormile, A. Piciocchi, F. Fazio, M. Capriata, S. Sorella, E. Baldacci, A. Chistolini, M.T. Petrucci, C. Santoro | Sapienza University of Roma, Italy

  Mario Biglietto

  26-10-2026

  https://doi.org/10.4081/btvb.2026.869

  20

  PDF: 9

• CO038 | PROGNOSTIC PERFORMANCE OF BLEEDING SEVERITY CLASSIFICATIONS IN HOSPITALIZED PATIENTS WITH GASTROINTESTINAL BLEEDING ON DIRECT ORAL ANTICOAGULANTS G. Maraziti, A. Vinci, M. Verso | Internal and Emergency Medicine - Stroke Unit, S. Maria della Misericordia Hospital – University of Perugia, Perugia, Italy

  Giorgio Maraziti

  26-10-2026

  https://doi.org/10.4081/btvb.2026.740

  26

  PDF: 9

• PO72 | Fondaparinux in patient with active tuberculosis T. Marrazzo¹, R. Parrella², A. Botta², A. Pontarelli², M.P. Ursi³, A. Karruli⁴, R. Albisinni⁵ | ¹UOC Medicina Interna e dei Trapianti, Ospedale Monaldi, Napoli, Italy; ²UOC Malattie Infettive ad Indirizzo Respiratorio, Ospedale Cotugno Azienda dei Colli, Napoli, Italy; ³UOC MECAU Ospedale CTO Azienda dei Colli, Napoli, Italy; ⁴Malattie Infettive e Tropicali, Ospedale di Tirana, Albania; ⁵UOC CCH Generale, Ospedale Monaldi Azienda dei Colli, Napoli, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.341

  637

  PDF: 17

• CO33 | Acquired hemophilia A in Liguria, Italy: what six years of data reveal C. Vernarecci¹, A. C. Molinari¹, P. Ballarino², M. Caiti², E. Cenni², P. Moscatelli², L. Banov¹ | ¹IRCCS Istituto Giannina Gaslini, Genova; ²IRCCS Policlinico San Martino, Genova, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.240

  616

  PDF: 30

• PO083 | WOMEN AND HEMOPHILIA: ASSESSMENT OF THE BLEEDING PHENOTYPE – ANALYSIS OF THE BRESCIA COHORT N. Portesi, S. Pontoglio, G. Carracchia, G. Albrici, E. Bertoni, G. Martini | ASST Spedali Civili di Brescia, Italy

  Nicola Portesi

  26-10-2026

  https://doi.org/10.4081/btvb.2026.899

  29

  PDF: 5

• PO70 | Clinical safety and monitoring of apixaban combined with tacrolimus and everolimus in kidney transplant patients: a prospective study S. Guglielmo¹, E. De Bon², L. Scarano¹, R. Fabris¹, E. Pierobon³, S. Barbar² | ¹Internal Medicine, Department of Medicine, Azienda ULSS 6 Euganea, Cittadella; ²Thrombotic and Hemorrhagic Disorders Unit, Department of Medicine, Azienda ULSS 6 Euganea, Cittadella; ³Nephrology and Dialysis Unit, Azienda ULSS 6 Euganea, Cittadella and Camposampiero, Padova, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.339

  640

  PDF: 25

• CS02 | Functional and structural impairments of the cerebral microcirculation in a mouse model of hemophilia A G. Venturin¹, C. Olgasi², C. Borsotti¹, P.E. Di Simone¹, E. Spicuglia¹ A. Cucci¹, C. Sgromo¹, A. Follenzi^2,3 | ¹Department of Health Science, Università del Piemonte Orientale, Novara; ²Department of Translational Medicine, Università del Piemonte Orientale, Novara; ³Department of Attività Integrate Ricerca Innovazione, Azienda Ospedaliero-Universitaria SS. Antonio e Biagio e C. Arrigo, Alessandria, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.197

  753

  PDF: 21

• PO33 | Whole blood hypercoagulable profiles in patients with rheumatoid arthritis L. Spiezia¹, A. Giollo², C. Samà¹, A. Benetti¹, L. Di Luozzo², M. Salvato², A. Doria², P. Simioni¹ | ¹First Chair of Internal Medicine, Thrombotic and Hemorrhagic Diseases Unit, Department of Medicine, University Hospital of Padova; ²Rheumatology Unit, Department of Medicine, University Hospital of Padova, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.296

  632

  PDF: 17

• PO115 | AL AMYLOIDOSIS IN A PATIENT WITH SEVERE HEMOPHILIA A AND INHIBITORS WHO HAD A MONOZYGOTIC TWIN: SAME GENES, DIFFERENT OUTCOMES M. Biglietto, S. Sorella, S. Ligia, C. Andriola, R. Mormile, E. Baldacci, A. Chistolini, C. Santoro | Sapienza, University of Rome, Italy

  Mario Biglietto

  26-10-2026

  https://doi.org/10.4081/btvb.2026.931

  24

  PDF: 10

• PO004 | SEX-RELATED DIFFERENCES AND PREDICTORS OF MORTALITY IN MAJOR ORTHOPEDIC SURGERY: INSIGHTS FROM THE ORTHO-START REGISTRY A. de Laurenzo¹, E. Antonucci², C. Rostagno³, D. Barcellona⁴, D. Colaizzo¹, G. di Rienzo⁵, F. Gorgoglione¹, G. Maccagnano⁶, F. Marongiu², M. Mastroianno¹, M. Marzolo⁷, L. Mirabella⁶, B. Moretti⁸, A.M. Moretti⁹, A. Ostuni⁶, G. Palareti², M. Margaglione⁶, E. Grandone^1|6 | ¹Fondazione I.R.C.C.S. “Casa Sollievo della Sofferenza”, S. Giovanni R. (Foggia), Italy; ²Fondazione Arianna, Bologna, Italy; ³Department of Internal and Postoperative Medicine, Careggi University Hospital, Firenze, Italy; ⁴Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy; ⁵UOC Patologia Clinica-Ospedale Altamura ASL Bari, Italy; ⁶University of Foggia, Policlinico Riuniti Foggia, Italy; ⁷Angiology Unit, Ospedale di Rovigo, Rovigo, Italy; ⁸School of Medicine, AOU Consorziale Policlinico, University of Bari "Aldo Moro", Italy; ⁹President of GISeG (Italian Group for Health and Gender), Bari, Italy

  Elvira Grandone

  26-10-2026

  https://doi.org/10.4081/btvb.2026.820

  22

  PDF: 8

• CO-46 | MILD HEMOPHILIA A AND JOINT HEALTH IN REAL LIFE: IS THAT AN EMERGING ISSUE? A SINGLE CENTER EXPERIENCE G. Murante^1|2|3, F. Valeri^1|2, S. Bergonzi^1|2|3, M. Capetta^1|2|3, C. Dainese^1|2, A. Valpreda⁴, R. Pastorino^1|3, F. Bocchi^1|3, B. Bruno^2|3, A. Borchiellini^1|2 | ¹Regional Centre for Hemorrhagic and Thrombotic Diseases, AOU Città della Salute e della Scienza of Turin, Italy; ²Division of Hematology, AOU Città della Salute e della Scienza, University of Turin, Italy; ³Dep. of Molecular Biotechnology and Health Sciences, University of Turin, Italy; ⁴Central Lab. Baldi and Riberi, AOU Città della Salute e della Scienza of Turin, Italy

  Giovanni Murante

  14-10-2026

  https://doi.org/10.4081/btvb.2026.656

  43

  PDF: 14

• CO030 | MILD HEMOPHILIA A AND JOINT HEALTH IN REAL LIFE: IS THAT AN EMERGING ISSUE? A SINGLE CENTER EXPERIENCE G. Murante^1|2|3, F. Valeri^1|2, S. Bergonzi^1|2|3, M. Capetta^1|2|3, C. Dainese^1|2, A. Valpreda⁴, R. Pastorino^1|3, F. Bocchi^1|3, B. Bruno^2|3, A. Borchiellini^1|2 | ¹Regional Centre for Hemorrhagic and Thrombotic Diseases, AOU Città della Salute e della Scienza di Torino, Italy; ²Division of Hematology, AOU Città della Salute e della Scienza, Università di Torino, Italy; ³Dep. of Molecular Biotechnology and Health Sciences, University of Turin, Italy; ⁴Central Lab. Baldi and Riberi, AOU Città della Salute e della Scienza di Torino, Italy

  Giovanni Murante

  26-10-2026

  https://doi.org/10.4081/btvb.2026.732

  26

  PDF: 10

• PO131 | BEYOND THE INHIBITOR TITER: THE IMPORTANCE OF EARLY COMBINED IMMUNOSUPPRESSIVE THERAPY IN THE MANAGEMENT OF ACQUIRED HEMOPHILIA A M. Luongo¹, P. Massaro¹, M. Di Mascio¹, P.G. Simeone², F. Santilli², S. Verna¹ | ¹Immunohematology Service, Asl 02 Abruzzo, Chieti, Italy; ²Department of Medicine and Aging Sciences, and Center for Advanced Studies and Technology, “G. d’Annunzio” University of Chieti–Pescara, Italy

  Myriam Luongo

  26-10-2026

  https://doi.org/10.4081/btvb.2026.947

  26

  PDF: 8

• PO86 | Emicizumab in patients with moderate hemophilia A and severe bleeding phenotype: single-center real-world experience A.L. Faccini, M. Biglietto, S. Sorella, E. Crisanti, M. Antonacci, R. Mormile, R. Ciciani, E. Baldacci, C. Santoro, S. Ligia | Hematology, Department of Translational and Precision Medicine Sapienza University of Roma, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.355

  754

  PDF: 26

• CO011 | GENERATION OF A TARGETING NON-BLOCKING TISSUE FACTOR ANTIBODY FOR SAFE AND EFFICACIOUS CANCER TREATMENTS A. Metelli¹, P. Nisticò¹, J. Wrangle² | ¹IRCCS Regina Elena National Cancer Institute, Roma, Italy; ²Medical University of South Carolina, Charleston, USA

  Alessandra Metelli

  26-10-2026

  https://doi.org/10.4081/btvb.2026.713

  38

  PDF: 8