Thrombophilia work-up and clinical outcomes in Indian patients with unprovoked venous and arterial thrombosis aged 18-50 years | BTVB Bioequivalence of von Willebrand factor-containing concentrates: implications for von Willebrand disease | BTVB Cardiovascular risk in hormone replacement therapy | BTVB Direct oral anticoagulants: does one dose fit all? Why, when and how testing | BTVB Cardiovascular risk profile evolution over 15 years: CV-PREVITAL vs Moli-sani Study | BTVB Launch of National Registry for Congenital Hematological Disorders in Palestine: Haemo-PAL | BTVB
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Bleeding, Thrombosis and Vascular Biology

Editor-in-Chief: Giovanni de Gaetano, Italy | eISSN: 2785-5309

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  • Anticoagulation in obese patients: challenges and strategies

    Alice Lipari, Esmeralda Capristo, Antonietta Ferretti, Erica De Candia
    18-09-2025
    https://doi.org/10.4081/btvb.2025.174
    1795
    PDF: 249
    HTML: 181
    XML: 74
  • Executive summary of the SISET position paper on the management of antithrombotic therapy in left ventricular thrombus

    Emanuele Valeriani, Arianna Pannunzio, Danilo Menichelli, Domenico Prisco, Walter Ageno, Daniele Pastori, Pasquale Pignatelli
    16-12-2025
    https://doi.org/10.4081/btvb.2025.401
    235
    PDF: 52
    HTML: 17
  • Factor XI inhibitors: a new option for the prevention and treatment of cancer-associated thrombosis

    Marcello Di Nisio, Matteo Candeloro, Nicola Potere, Ettore Porreca, Jeffrey I. Weitz
    16-05-2024
    https://doi.org/10.4081/btvb.2024.118
    1529
    PDF: 754
  • CO29 | Emergency room physicians and oral anticoagulants related bleeding D. Barcellona1,2, G. Melis1, A. Bussu1, M. Orrù1, Ml. Caddeo1, E. Antonucci2, A. Mameli1, F. Marongiu1,2 | 1SSD Emostasi e Trombosi, AOU Cagliari; 2Fondazione Arianna, Bologna, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.235
    482
    PDF: 0
  • Pleiotropic effects of anti-thrombotic therapies: have direct oral anticoagulants any anti-inflammatory effect?

    Anna Maria Gori, Eleonora Camilleri, Alessia Bertelli, Angela Rogolino, Francesca Cesari, Elena Lotti, Tommaso Capobianco, Walther Iannotti, Betti Giusti , Rossella Marcucci
    14-12-2022
    https://doi.org/10.4081/btvb.2022.50
    1502
    PDF: 442
  • CO08 | The utility of urine qualitative assessment for direct oral anticoagulants in routine clinical practice F. Schieppati1,2, P. Gomez-Rosas1,3, C. Ambaglio1, V. Brusegan1, Oc. Cretu1,2, E. Galimberti1, F. Zunino1, L. Barcella1, J. Harenberg4,5, A. Falanga1,2, M. Marchetti1,2 | 1Immunohematology and Transfusion Medicine, Hospital Papa Giovanni XXIII, Bergamo, Italy; 2School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy; 3Maastricht University Medical Center, Cardiovascular Research Institute Maastricht, Maastricht, The Netherlands; 4Ruprecht Karls University of Heidelberg, Germany; 5Germany DOASENSE GmbH, Heidelberg, Germany

    22-10-2025
    https://doi.org/10.4081/btvb.2025.212
    565
    PDF: 0
  • Stroke in women: anticoagulation in a complicated puzzle

    Francesco Marongiu, Elvira Grandone, Silvia Marongiu, Antonella Mameli, Doris Barcellona
    26-08-2024
    https://doi.org/10.4081/btvb.2024.137
    1467
    PDF: 352
  • Personalized bleeding risk assessment for atrial fibrillation patients on direct oral anticoagulants: the DOAC score

    Paolo Prandoni
    11-10-2023
    https://doi.org/10.4081/btvb.2023.97
    1878
    PDF: 339
  • PO81 | Direct oral anticoagulants in atypical site vein thrombosis: a single centre experience focused on cancer patients U. Mazzarelli1, A. Guida1, L. Agrelli1, M. Amato1, R. Guarrasi2, L. Santaniello2, C. Cardamone1, P. Vitale1, M. Triggiani1 | 1Centro per le Malattie Emorragiche Congenite e Malattie Trombotiche UOC Clinica Immunologica e Reumatologica AOU S. Giovanni di Dio e Ruggi d’Aragona, Salerno; 2UOC Clinica Oncologica AOU S. Giovanni di Dio e Ruggi d’Aragona, Salerno, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.350
    495
    PDF: 0
  • New perspectives for prevention of the post-thrombotic syndrome

    Paolo Prandoni
    22-03-2022
    https://doi.org/10.4081/btvb.2022.20
    2058
    PDF: 544
  • PO43 | Extended treatment with reduced dose of direct oral anticoagulants in patients with venous thromboembolism: a retrospective study A. Pannunzio1, E. Valeriani1, I.M. Palumbo1, D. Menichelli1, T. Brogi2, S. Marucci2, D. Pastori2, P. Pignatelli2 | 1Department of General Surgery and Surgical Specialty, Sapienza University of Roma; 2Department of Clinical Internal, Anesthesiological and Cardiovascular Sciences, Sapienza University of Roma, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.306
    468
    PDF: 0
  • Safety and efficacy of treatment with vitamin K antagonists in patients managed in a network of anticoagulation services or as routine general care

    Gianfranco De Girolamo, Luca Sarti, Sonia Cecoli, Karin Bonora, Chiara Ajolfi, Francesco Bellelli, Valeria Coluccio, Gualtiero Palareti, Marco Marietta
    15-04-2022
    https://doi.org/10.4081/btvb.2022.9
    964
    PDF: 300
    Supplementary Files: 113
  • CO04 | Direct oral anticoagulants in antiphospholipid syndrome: a single center real-life experience A. Hoxha1, E. Campello1, F. Ahmad2, L. Spiezia1, P. Scarinzi1, G. Gobbo1, S. Gavasso1, F. Sartorello1, C. Simion1, E. Zanon1, P. Simioni1 | 1Internal Medicine Unit, Thrombotic and Haemorrhagic Centre, Department of Medicine - DIMED; 2Department of Statistical Sciences) University of Padova, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.209
    592
    PDF: 0
  • Direct oral anticoagulants: does one dose fit all? Why, when and how testing

    Armando Tripodi
    15-01-2026
    https://doi.org/10.4081/btvb.2026.418
    910
    PDF: 197
  • PO31 | Comparative analysis of anticoagulant therapy in patients over 90 years old: vitamin K antagonists versus direct oral anticoagulants G. Sottilotta1, P. Arrigo2, S. Cuzzocrea1, D. Megalizzi1, F. Luise3 | 1UOSD Microcitemie, Emostasi e Trombosi, Grande Ospedale Metropolitano di Reggio Calabria; 2Associazione Italiana Pazienti Anticoagulati, Sezione di Reggio Calabria; 3Laboratorio Analisi. Grande Ospedale Metropolitano di Reggio Calabria, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.292
    434
    PDF: 0
  • PO83 | A case of deep vein thrombosis in a patient with systemic mastocytosis M. Leotta, A. Ierardi, A. Strangio, R C. Santoro | UO Emofilia, Emostasi e Trombosi, AOU R Dulbecco, Catanzaro

    22-10-2025
    https://doi.org/10.4081/btvb.2025.352
    577
    PDF: 0
  • PO13 | Monitoring of anti-factor XA activity levels in patients treated with direct oral anticoagulants and concomitant tyrosine kinase inhibitors agents: a monocentric experience E. Santacroce1,2, C. Santoro1, E. Baldacci1, S. Ligia1, R. Mormile1, M. Biglietto1, M. Totaro1, F. R. Mauro1, M. Breccia1, A. Chistolini1 | 1Department of Translational and Precision Medicine, Haematology, Sapienza University of Roma; 2Department of Clinical and Molecular Medicine, Sapienza University of Roma, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.313
    460
    PDF: 0
  • Evaluation of Coaguchek® Pro II coagulation testing device performance to assess direct oral anticoagulant action. The DOAC-CHECK study

    Cristina Legnani, Michela Cini, Sophie Testa, Alberto Tosetto, Claudia Dellanoce, Stefania Bellesso, Giuseppe Carli, Ilaria Nichele, Laura Lissandrini, Serena Zorzi, Emilia Antonucci, Gualtiero Palareti
    01-12-2022
    https://doi.org/10.4081/btvb.2022.37
    1952
    PDF: 390
  • Location of metastasis and complications in patients with venous thromboembolism and cancer: a systematic review

    Maria Barca-Hernando, Victor Garcia-Garcia, Luis Jara-Palomares
    16-05-2024
    https://doi.org/10.4081/btvb.2024.114
    870
    PDF: 605
  • Venous thromboembolism treatment in patients with cancer: reflections on an evolving landscape

    Agnes Y.Y. Lee
    29-02-2024
    https://doi.org/10.4081/btvb.2024.111
    1815
    PDF: 707
  • PO53 | Effectiveness and safety of DOACS in patients with renal transplantation A. Ierardi, A. Strangio, M. Leotta, R C. Santoro | UO Emofilia, Emostasi e Trombosi, AOU Renato Dulbecco, Catanzaro, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.322
    447
    PDF: 0
  • Factor XI inhibitors in adjunct to antiplatelet therapy: the ultimate dual-pathway inhibition?

    Mattia Galli, C. Michael Gibson, Dominick J. Angiolillo
    03-08-2023
    https://doi.org/10.4081/btvb.2023.90
    1804
    PDF: 621
  • PO77 | The clinical awareness of mixing test interpretation in the era of complex reporting algorithm: do we forget the origins? A. Fassina, L. De Valentin, S. Luzi, R. Turrini, A. Antico, L. Zardo | Laboratorio Analisi Castelfranco Veneto, ULSS Marca Trevigiana, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.346
    469
    PDF: 0
  • Management of anticoagulation in atrial fibrillation patients in Italy: insight from the Atrial Fibrillation-Survey on Anticoagulated Patients Register (AF-START)

    Daniela Poli, Walter Ageno, Emilia Antonucci, Salvatore Bradamante, Eugenio Bucherini, Paolo Chiarugi, Antonio Chistolini, Benilde Cosmi, Anna Falanga, Antonio Insana, Domenico Lione, Rosa Maria Lombardi, Giuseppe Malcangi, Rossella Marcucci, Giuliana Martini, Lucilla Masciocco, Carmelo Paparo, Daniele Pastori, Simona Pedrini, Vittorio Pengo, Pasquale Pignatelli, Andrea Toma, Sophie Testa, Gualtiero Palareti
    27-06-2023
    https://doi.org/10.4081/btvb.2023.84
    1772
    PDF: 469
    Supplementary File: 218
  • CO09 | Long term effectiveness and safety of direct oral anticoagulants in patients with factor V Leiden and/or prothrombin gene mutation and venous thromboembolism: a single centre, retrospective cohort study I.M. Palumbo1, E. Valeriani1,2, A. Pannunzio1, S. Marucci3, D. Menichelli1, D. Pastori3,4, P. Pignatelli3 | 1Department of General Surgery and Surgical Specialty, Sapienza University of Roma; 2Department of Infectious Disease, Azienda Ospedaliero-Universitaria Policlinico Umberto I, Roma; 3Department of Clinical Internal, Anaesthesiologic and Cardiovascular Sciences, Sapienza University of Roma; 4IRCCS Neuromed, Pozzilli, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.213
    572
    PDF: 0
  • PO70 | Clinical safety and monitoring of apixaban combined with tacrolimus and everolimus in kidney transplant patients: a prospective study S. Guglielmo1, E. De Bon2, L. Scarano1, R. Fabris1, E. Pierobon3, S. Barbar2 | 1Internal Medicine, Department of Medicine, Azienda ULSS 6 Euganea, Cittadella; 2Thrombotic and Hemorrhagic Disorders Unit, Department of Medicine, Azienda ULSS 6 Euganea, Cittadella; 3Nephrology and Dialysis Unit, Azienda ULSS 6 Euganea, Cittadella and Camposampiero, Padova, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.339
    465
    PDF: 0
  • CO05 | Long-term management of upper extremity catheter-related thrombosis in female patients with cancer: a retrospective cohort study Chiara Cavallaro1,2, Paolo Santini1,2, Laura Leoni3, Carolina Mosoni1,2, Silvia D’Ambrosio1,2, Francesco Mancinetti1,2, Nicola Coletta1,2, Michela Iorio1,2, Angelo Porfidia1,2, Alessandro D’Errico1,2, Rosa Talerico1,2, Roberto Pola1,2 | 1Department of Aging, Orthopedic, and Rheumatologic Sciences, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome; 2Università Cattolica del Sacro Cuore, Rome; 3Vita-Salute University, San Raffaele Hospital IRCCS, Milan, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.309
    500
    PDF: 0
  • PO18 | Does muscle mass matter? Appendicular lean mass as a determinant of anti-XA activity in elderly patientes B.M. Zanforlini1, V. Bernardi1, E. Campello2, E.M. Bicego1, C. Curreri1, A. Vaticano1, C. Sartori1, L. Manfron1, A. Perencin1, P. Rollo1, A. Baruffol1, L. Ruoso1, C. Simion2, C. Bulato2, P. Berto2, P. Simioni2, G. Sergi1 | 1Department of Medicine, Geriatrics Section, University of Padova; 2Haemorrhagic and Thrombotic Diseases Unit, Department of Medicine DIMED, Padova University Hospital, Padova, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.278
    457
    PDF: 0
  • PO37 | Single centre experience on anticoagulation in carriers of non-mild inherited thrombophilia: direct oral anticoagulants (DOAC) efficacy and safety M. D’uva1,2, G. La Barba1, G. Montanaro1, M. Di Ianni1,2, P. Ranalli1,2 | 1Hematology Unit, S. Spirito Hospital, Pescara; 2Department of Medicine and Aging Sciences, D’Annunzio University, Chieti, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.300
    458
    PDF: 0
  • PO93 | Use of DOACS in heart transplantation recipients T. Marrazzo1, A. Delle Femine1, C. Amarelli2, R. Albisinni3 | 1UOC Medicina Interna e dei Trapianti, Ospedale Monaldi Azienda dei Colli, Napoli; 2UOSD CCH dei Trapianti, Ospedale Monaldi Azienda dei Colli, Napoli; 3UOC CCH Generale, Ospedale Monaldi Azienda dei Colli, Napoli, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.363
    538
    PDF: 0
  • PO57 | Direct oral anticoagulant determination in urine samples compared to plasma concentrations in outpatients with atrial fibrillation and obesity A. Pannunzio1, I.M. Palumbo1, D. Menichelli1, V. Cammisotto2, V. Castellani3, E. Baldacci4, R. Mormile4, A. Chistolini4, G. Bernardini5, N. Porcu1, D. Pastori2, J. Harenberg6, F. Violi2, P. Pignatelli2 | 1Department of General Surgery, Surgical Specialties and Organ Transplantation Paride Stefanini, Sapienza University of Roma, Italy; 2Department of Clinical Internal, Anesthesiological and Cardiovascular Sciences, Sapienza University of Roma, Italy; 3Department of Translational and Precision Medicine, Sapienza University of Roma, Italy; 4Department of Hematology, Oncology and Dermatology, Sapienza University of Roma, Italy; 5U.O.S.D. Medicina Rigenerativa DAI, Medicina Diagnostica e Radiologia, Policlinico Umberto 1, Roma, Italy; 6Ruprecht Karls University of Heidelberg, Germany

    22-10-2025
    https://doi.org/10.4081/btvb.2025.326
    392
    PDF: 0
  • PO89 | Apixaban for secondary prevention of venous thromboembolism in hemodialysis patients: pharmacokinetic profile and safety outcomes S. Guglielmo1, E. De Bon2, L. Scarano1, R. Fabris1, E. Pierobon3, S. Barbar2 | 1Internal Medicine, Department of Medicine; 2Thrombotic and Hemorrhagic Disorders Unit, Department of Medicine; 3Nephrology and Dialysis Unit, Azienda ULSS 6 Euganea, Cittadella and Camposampiero, Padua, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.359
    561
    PDF: 0
  • Management of atrial fibrillation: a practical and useful synopsis of last guidelines

    Gualtiero Palareti
    24-02-2025
    https://doi.org/10.4081/btvb.2025.168
    1163
    PDF: 103
  • Pathways for lower extremity superficial vein thrombosis management in an academic medical center

    Gisoo Imani, Aaron Wilson, Sara Vazquez, Daniel M. Witt
    24-03-2025
    https://doi.org/10.4081/btvb.2025.155
    608
    PDF: 166
  • PO72 | Fondaparinux in patient with active tuberculosis T. Marrazzo1, R. Parrella2, A. Botta2, A. Pontarelli2, M.P. Ursi3, A. Karruli4, R. Albisinni5 | 1UOC Medicina Interna e dei Trapianti, Ospedale Monaldi, Napoli, Italy; 2UOC Malattie Infettive ad Indirizzo Respiratorio, Ospedale Cotugno Azienda dei Colli, Napoli, Italy; 3UOC MECAU Ospedale CTO Azienda dei Colli, Napoli, Italy; 4Malattie Infettive e Tropicali, Ospedale di Tirana, Albania; 5UOC CCH Generale, Ospedale Monaldi Azienda dei Colli, Napoli, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.341
    464
    PDF: 0
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Vol. 5 No. 1 (2026)
In this issue
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Americo Bonanni
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Hemophilia-free mind: a call to action
Tiziano Martini et al.
10 March 2026

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Bleeding, Thrombosis and Vascular Biology

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