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• CO-27 | INNOVATIVE USE OF EPTACOG BETA TO TREAT ACUTE ELBOW HEMARTHROSIS IN A PEDIATRIC PATIENT WITH HEMOPHILIA B AND A HISTORY OF INHIBITORS, UNDERGOING SECONDARY PROPHYLAXIS WITH CONCIZUMAB L. Laterza¹, P. Giordano², G. Lassandro² | ¹University of Bari "Aldo Moro", Interdisciplinary Department of Medicine, Bari, Italy; ²Pediatric Haemophilia Center-AOUC Pol. Giovanni XXXIII, University of Bari “Aldo Moro”, Bari, Italy

  Luisa Laterza

  14-10-2026

  https://doi.org/10.4081/btvb.2026.637

  22

  PDF: 8
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  PO52 | MECHANISTIC POPULATION PHARMACOKINETIC/PHARMACODYNAMIC AND TIME-TO-EVENT MODELING SUPPORT SUSTAINED FACTOR XI INHIBITION AND SUPERIOR POST-OPERATIVE VENOUS THROMBOEMBOLISM PREVENTION WITH REGN7508^CAT O. Milberg¹, H. Abdallah¹, R.K. Lokken², R. Dingman¹, K.A. Meagher¹, P. Banerjee¹, M.E. Burczynski¹, E. Marin¹, A.P. Kithcart¹, D.E. Gutstein¹ | ¹Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA; ²Allucent, Cary, NC, USA

  ICTHIC 2026

  16-04-2026

  https://doi.org/10.4081/btvb.2026.544

  505

  PDF: 114

• CO-57 | NXT007 PROPHYLAXIS IN PEOPLE WITH HEMOPHILIA A WITH OR WITHOUT FACTOR VIII INHIBITORS: COMBINED ANALYSIS OF TWO PHASE I/II MULTIPLE-ASCENDING-DOSE STUDIES M.E. Mancuso^1|2, M. Shima³, J.M. Staber⁴, Y.C. Chen⁵, F.J. López-Jaime⁶, M.C. Shen⁷, G. Ventriglia⁸, M. Takeyama⁹, C. Schmitt⁸, Y.S. Park¹⁰, A. Kiialainen⁸, N. Mizuno¹¹, M. Niggli⁸, T. Miyake¹¹, D. Matino¹², T. Saito¹¹, V. Jiménez-Yuste¹³, R. Kobayashi¹¹, D. Hart¹⁴, K. Nogami¹⁵ | ¹Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milano, Italy; ²Center for Thrombosis and Hemorrhagic Diseases, IRCCS Humanitas Research Hospital, Rozzano, Milano, Italy; ³Thrombosis and Hemostasis Research Center, Nara Medical University, Kashihara, Nara, Japan; ⁴Stead Family Department of Pediatrics, Carver College of Medicine, University of Iowa, Iowa City, USA; ⁵Hemophilia Care and Research Center, Tri-Service General Hospital, National Defense Medical University, Taipei, Taiwan; ⁶Servicio de Hematología, Hospital Universitario Regional de Málaga / Instituto de Investigación Biomédica de Málaga (IBIMA), Málaga, Spain; ⁷Department of Internal Medicine, Changhua Christian Hospital, Changhua, Taiwan; ⁸F. Hoffmann-La Roche Ltd, Basel, Switzerland; ⁹Division of Hemophilia, National Hospital Organization, Osaka National Hospital, Osaka, Japan; ¹⁰Department of Pediatrics, Kyung Hee University Hospital at Gangdong, Seoul, South Korea; ¹¹Chugai Pharmaceutical Co., Ltd, Tokyo, Japan; ¹²McMaster University, Hamilton, Ontario, Canada; ¹³La Paz University Hospital-IdiPAZ, Autónoma University, Madrid, Spain; ¹⁴Roche Products Ltd, Welwyn Garden City, UK; ¹⁵Department of Pediatrics, Nara Medical University, Kashihara, Nara, Japan

  Maria Elisa Mancuso

  14-10-2026

  https://doi.org/10.4081/btvb.2026.667

  20

  PDF: 10

• BEST-08 | PERIOPERATIVE MANAGEMENT OF CHILDREN WITH MILD FACTOR VII DEFICIENCY UNDERGOING SURGERY: A RETROSPECTIVE COHORT STUDY B. Borsellino¹, T. Martini¹, I. Ricca², B. Pollio¹ | ¹Haemophilia Centre, Immune-Haematology and Transfusion Medicine, University Hospital “Città della Salute e della Scienza”, Torino, Italy; ²Transfusion Medicine, Ivrea Hospital, Ivrea, Italy

  Tiziano Martini

  14-10-2026

  https://doi.org/10.4081/btvb.2026.608

  71

  PDF: 7

• CO-36 | PLATELETS MATTER: THROMBIN GENERATION IN PLATELET‐RICH-PLASMA VS. PLATELET‐POOR‐PLASMA UNDER NON-REPLACEMENT THERAPIES IN HEMOPHILIA F. Bocchi^1|2, R. Pastorino^1|2, G. Murante^1|2|3, S. Bergonzi^1|2|3, M. Capetta^1|2|3, F. Valeri^2|3, C. Dainese^2|3, A. Valpreda⁴, B. Bruno^1|3, A. Borchiellini^2|3 | ¹Department of Molecular Biotechnology and Health Sciences, University of Turin, Italy; ²Regional Centre for Thrombotic and Hemorrhagic Diseases, AOU Città della salute e della Scienza di Torino, Italy; ³Division of Hematology, AOU Città della Salute e della Scienza, University of Turin, Italy; ⁴Central Lab Baldi and Riberi, AOU Città della salute e della Scienza di Torino, Italy

  Francesca Bocchi

  14-10-2026

  https://doi.org/10.4081/btvb.2026.646

  22

  PDF: 9
• 

  Neurovascular protective effects of nutritional interventions in ischemic brain injury

  Geetika Mehta, Pooja Mishra, Suyash Sharma, Rashmi Tripathi, Monika Sachdeva

  10-04-2026

  https://doi.org/10.4081/btvb.2026.436

  1718

  PDF: 181
• 

  Management of atrial fibrillation: a practical and useful synopsis of last guidelines

  Gualtiero Palareti

  24-02-2025

  https://doi.org/10.4081/btvb.2025.168

  1469

  PDF: 204

• CO-13 | USE OF THE MULTIDIMENSIONAL HEMOPHILIA PAIN QUESTIONNAIRE IN PATIENTS WITH SEVERE HEMOPHILIA A TREATED WITH EMICIZUMAB: A PILOT CROSS-SECTIONAL, SINGLE-CENTER STUDY I.L. Calcaterra, S. Donnarumma, G. D’Errico, C. De Luca, C. Caputo, P. Ciciola, E. Cimino, M. Di Minno | Università Federico II di Napoli, Italy

  Ilenia Lorenza Calcaterra

  14-10-2026

  https://doi.org/10.4081/btvb.2026.623

  62

  PDF: 7
• 

  PO17 | PREDICTIVE VALUE OF INFLAMMATORY AND ENDOTHELIAL BIOMARKERS FOR CANCER RISK IN HEALTHY INDIVIDUALS: EVIDENCE FROM THE HYPERCAN STUDY C. Ticozzi¹, S. Bolognini^1|2, P. Gomez-Rosas^1|3, F. Schieppati^1|2, G. Sampietro⁴, L. Barcella¹, M. Marchetti^1|2, A. Falanga^1|2 | ¹Immunohematology and Transfusion Medicine, Hospital Papa Giovanni XXIII, Bergamo, Italy; ²School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy; ³Maastricht University Medical Center, Cardiovascular Research Institute Maastricht (CARIM), Maastricht, The Netherlands; ⁴Unit of Epidemiology and Statistics, ATS Bergamo, Italy

  ICTHIC 2026

  16-04-2026

  https://doi.org/10.4081/btvb.2026.512

  428

  PDF: 96

• CO38 | Management of pregnancy, delivery, and postpartum in Italian carriers and women with hemophilia A and B S. Linari¹, B. Pollio², A. Ferretti³, M. Napolitano⁴, E. Grandone⁵, S. Siboni⁶, Ab. Aru⁷, E. Bertoni⁸, C. Biasoli⁹, I. Cantori¹⁰, P. Di Gregorio¹¹, G. Lassandro¹², G. Sottilotta¹³, A. Strangio¹⁴, Mr. Villa¹⁵, A. Rocino¹⁶, G. Castaman¹ | ¹Center for Bleeding Disorders and Coagulation, Careggi University Hospital, Firenze; ²Regional Reference Center for Inherited Bleeding and Thrombotic Disorders, Transfusion Medicine, Regina Margherita Children Hospital, Turin; ³Center for Hemorrhagic and Thrombotic Diseases, IRCCS A. Gemelli University Hospital Foundation, Roma; ⁴Department of Health Promotion, Maternal-Childhood, Internal Medicine of Excellence G. D’Alessandro, University of Palermo; ⁵Thrombosis and Hemostasis Unit, Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo; ⁶Angelo Bianchi Bonomi Hemophilia and Thrombosis Center and Fondazione Luigi Villa, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan; ⁷Pediatric Onco-Hematology Center, Microcitemico Hospital Cagliari; ⁸Pediatric Oncohematology and Bone Marrow Transplant “BMT” Unit, Children’s Hospital, Spedali Civili, Brescia; ⁹Hemophilia and Transfusion Center, Bufalini Hospital, Cesena; ¹⁰Hemophilia Center, Department of Transfusion Medicine, Hospital of Macerata; ¹¹Transfusion Medicine Department, SS. Annunziata Hospital, Chieti; ¹²B. Trambusti General and Specialised Pediatrics Unit, Giovanni XXIII Hospital, University of Bari; ¹³Hemophilia Center, Grande Ospedale Metropolitano, Reggio Calabria; ¹⁴Center for Hemorrhagic and Thrombotic Disorders, Pugliese Ciaccio Hospital, Catanzaro; ¹⁵Hemophilia and Thrombosis Center, Haematology Unit, Ospedale del Mare Hospital, Naples; ¹⁶Past President of the Italian Association of Hemophilia Centers, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.245

  575

  PDF: 15

• CO-44 | EVALUATION OF THE DEVIATION BETWEEN PRESCRIBED AND RECOMMENDED EMICIZUMAB DOSING IN PATIENTS WITH CONGENITAL HEMOPHILIA A A.C. Giuffrida¹, S. Abeysinghe Gunawardhana¹, S. Amato², F. Casoli², C. Recchi², M. Saggioro², E. Bonetti³, M. Bodini¹, G. Poli² | ¹Centro Emofilia, UOC Medicina Trasfusionale, AOUI Verona, Italy; ²UOC Laboratorio Analisi, AOUI Verona, Italy; ³UOC Oncoematologia Pediatrica, AOUI Verona, Italy

  Marco Bodini

  14-10-2026

  https://doi.org/10.4081/btvb.2026.654

  21

  PDF: 6
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  Mechanistic insights into cancer-associated thrombosis in brain cancer

  Janusz Rak

  16-04-2026

  https://doi.org/10.4081/btvb.2026.430

  337

  PDF: 143

• CO-26 | CLINICAL, LABORATORY AND METABOLIC CHARACTERISTICS OF ADULT PATIENTS WITH HEMOPHILIA A J. Di Paolo, M. Di Loreto, R. Malizia, M. Luongo, P. Massaro, M. Di Mascio, S. Verna | Immunohematology Service, Asl 02 Abruzzo, Chieti, Italy

  Josephine Di Paolo

  14-10-2026

  https://doi.org/10.4081/btvb.2026.636

  19

  PDF: 7

• PO10 | Clinical and laboratory features of long-Covid syndrome: a cross-sectional study of 1,337 Covid-19 survivors C. Ambaglio¹, S. V. Benatti², C. J. Tartari^1,3, L. Russo^1,3, S. Bolognini^1,3, C. Ticozzi¹, F. Schieppati¹, V. Brusegan¹, S. Venturelli², L. Barcella¹, M. Rizzi², M. Marchetti^1,3, A. Falanga^1,3 | ¹Department of Immunohematology and Transfusion Medicine, Papa Giovanni XXIII Hospital, Bergamo; ²Division of Infectious Diseases, Papa Giovanni XXIII Hospital, Bergamo; ³Department of Medicine and Surgery, University of Milan Bicocca, Monza, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.272

  647

  PDF: 18
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  Location of metastasis and complications in patients with venous thromboembolism and cancer: a systematic review

  Maria Barca-Hernando, Victor Garcia-Garcia, Luis Jara-Palomares

  16-05-2024

  https://doi.org/10.4081/btvb.2024.114

  1059

  PDF: 1138

• CO24 | Extracellular vesicles profiles in patients with wild-type transthyretin amyloidosis S. Toffanin¹, L. Spiezia¹, C.M. Radu¹, A. Napolitano¹, A. Benetti¹, C. Samà¹, E. Campello¹, L. De Michieli², G. Sinigiani², A. Cipriani², P. Simioni¹ | ¹First Chair of Internal Medicine, Department of Medicine, University-Hospital of Padua Medical School, Padua; ²Department of Cardiac, Thoracic and Vascular Sciences and Public Health, University of Padua, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.230

  669

  PDF: 14

• CO-34 | SIMPLIFIED PERIOPERATIVE MANAGEMENT WITH N8-GP (TUROCTOCOG ALFA PEGOL) IN MAJOR ABDOMINAL SURGERY IN MILD HEMOPHILIA A WITH SEVERE BLEEDING PHENOTYPE: A CASE REPORT J. Di Paolo, R. Malizia, M. Luongo, P. Massaro, M. Di Mascio, S. Verna | Immunohematology Service, ASL 02 Abruzzo, Chieti, Italy

  Josephine Di Paolo

  14-10-2026

  https://doi.org/10.4081/btvb.2026.644

  17

  PDF: 6
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  PO70 | HEMOSTATIC ABNORMALITIES IN A PATIENT WITH WALDENSTRÖM'S MACROGLOBULINEMIA M. Gagliardi, L. Capone, A. Ciampa | Haemostasis Centre, AORN Moscati, Avellino, Italy

  ICTHIC 2026

  16-04-2026

  https://doi.org/10.4081/btvb.2026.559

  484

  PDF: 110

• CO-65 | COVID-19-ASSOCIATED HYPERCOAGULABILITY IN TYPE 2B VON WILLEBRAND DISEASE: INSIGHTS FROM GLOBAL HEMOSTATIC ASSAYS I. Condonato, C. Simion, E. Zanon, P. Simioni | Hemophilia Center, University Hospital of Padua, Italy

  Irene Condonato

  14-10-2026

  https://doi.org/10.4081/btvb.2026.675

  19

  PDF: 9

• PO63 | Atypical venous thrombosis in young patient with systemic lupus erythematosus and high-risk APL profile: provoked or not? E. Marrone, A. Parisi, G. Di Monda, F. Gallucci, D. Morelli, C. Romano, U. Malgeri, D. D’Auria, P. Morella | Internal Medicine Unit 3, Cardarelli Hospital, Naples, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.332

  596

  PDF: 21
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  Importance of assessment of carotid plaques in the managementof acute ischemic stroke: floating intracarotid plaque

  Marwa Eltemamy, Robert Namushi, Narayanamoorthi Saravanan

  06-09-2023

  https://doi.org/10.4081/btvb.2023.79

  1456

  PDF: 393

• CO-89 | FEMORAL FRACTURE SURGERY IN AN ELDERLY, FRAIL PATIENT WITH ACQUIRED HEMOPHILIA A RECEIVING EMICIZUMAB PROPHYLAXIS: A CASE REPORT C. Simion^1|2, E. Zanon^1|2, B. Stocco^1|2, F. Sartorello¹, C. Bulato¹, G. Saggiorato¹, P. Simioni^1|2 | ¹First Chair of Internal Medicine and Thrombotic and Haemorrhagic Diseases Unit, Department of Medicine, Padova University Hospital, Italy; ²Hemophilia Center, Padova University Hospital, Italy

  Chiara Simion

  14-10-2026

  https://doi.org/10.4081/btvb.2026.699

  20

  PDF: 12

• CO-43 | VALIDATION OF THROMBIN GENERATION MEASUREMENT IN PLATELET-RICH PLASMA: EVOLUTION IN THE ST GENESIA^® SYSTEM F. Bocchi^1|2, R. Pastorino^1|2, G. Murante^1|2|3, S. Bergonzi^1|2|3, M. Capetta^1|2|3, F. Valeri^2|3, C. Dainese^2|3, A. Valpreda⁴, B. Bruno^1|3, A. Borchiellini^2|3 | ¹Department of Molecular Biotechnology and Health Sciences, University of Turin, Italy; ²Regional Centre for Thrombotic and Hemorrhagic Diseases, AOU Città della salute e della Scienza di Torino, Italy; ³Division of Hematology, AOU Città della Salute e della Scienza, University of Turin, Italy; ⁴Central Lab Baldi and Riberi, AOU Città della salute e della Scienza di Torino, Italy

  Francesca Bocchi

  14-10-2026

  https://doi.org/10.4081/btvb.2026.653

  17

  PDF: 6

• PO39 | Bleeding events in Von Willebrand disease type 1 yearly treatable with desmopressin A. Gringeri^1,2, P.M. Mannucci³, M. Gringeri⁴, G. Castaman⁵, F. Peyvandi^3,6 | ¹Fondazione Charta, Milan; ²Centro di Sanità Solidale, Lucca; ³Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center and Fondazione Luigi Villa, Milan; ⁴Department of Medical Biotechnologies and Translational Medicine, Postgraduate School of Clinical Pharmacology and Toxicology, University of Milan; ⁵Centre for Bleeding Disorders and Coagulation, Careggi University Hospital, Firenze; ⁶Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.302

  635

  PDF: 23
• 

  PO50 | SUB-ANALYSIS OF INTERIM RESULTS FROM A PHASE 2 STUDY INVESTIGATING REGN9933^A2 AND REGN7508^CAT FOR THE PREVENTION OF CONTACT-MEDIATED VENOUS THROMBOEMBOLISM IN PATIENTS WITH ACTIVE CANCER UNDERGOING PERIPHERALLY INSERTED CENTRAL CATHETER PLACEMENT (ROXI-CATH) J. Zwicker^1,2, A.P. Kithcart³, J. Kaplan³, Y-C. Cheng³, J.G. Raya³, J. Xiao³, S. Li³, K. Musgrave⁴, D.E. Gutstein³, G. Piazza⁵ | ¹Memorial Sloan Kettering Cancer Center, New York, NY, USA; ²Weill Cornell Medical Center, New York, NY, USA; ³Regeneron Pharmaceuticals, Inc. , Tarrytown, NY, USA; ⁴Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK; ⁵Brigham and Women’s Hospital, Boston, MA, USA

  ICTHIC 2026

  16-04-2026

  https://doi.org/10.4081/btvb.2026.542

  483

  PDF: 126

• PO09 | Comparison of different aggregometry methods for evaluation of platelet function in patients with myeloproliferative neoplasms C. Fortino, I. Bertozzi, D. Regazzo, L. Gianesello, G. Nuozzi, F. Sartorello, V. Azzaro, G. Saggiorato, A. Bertomoro, P. Simioni | First Medical Clinic, Department of Medicine – DIMED, Università degli Studi di Padova, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.271

  552

  PDF: 12
• 

  Coagulome and tumor microenvironment: impact of oncogenes, cellular heterogeneity and extracellular vesicles

  Nadim Tawil, Lata Adnani, Janusz Rak

  16-05-2024

  https://doi.org/10.4081/btvb.2024.109

  1124

  PDF: 1116

• CO-55 | DEVELOPMENT OF ENGINEERED LONG-ACTING BYPASSING FX VIA ALBUMIN FUSION FOR HEMOPHILIA WITH INHIBITORS A. Martucci¹, R. Tarantino¹, K.H. Aaen², M. Pinotti¹, J.T. Andersen², A. Branchini¹ | ¹Department of Life Sciences and Biotechnology, University of Ferrara, Ferrara, Italy; ²Institute of Clinical Medicine, Department of Pharmacology, University of Oslo, Norway

  Alessandro Martucci

  14-10-2026

  https://doi.org/10.4081/btvb.2026.665

  19

  PDF: 8

• CO23 | Markers of inflammation and hypofibrinolysis are associated with cognitive dysfunction and motor performances in atrial fibrillation patients on oral anticoagulant therapy: insights from the Strat-AF study F. Alfano^1,2, F. Cesari^1,2, A.M. Gori^1,2, M. Berteotti^1,2, E. Salvadori³, B. Giusti^1,2, A. Bertelli^1,2, F. Fratini⁴, A. Rogolino^1,2, B. Formelli^4,5, F. Pescini^4,5, E. Fainardi⁶, E. Barucci⁴, G. Salti⁵, A. Cavaliere⁴, A. Ginestroni⁶, A. Poggesi^4,5, R. Marcucci^1,2 | ¹Department of Experimental and Clinical Medicine, University of Firenze; ²Center for Atherothrombotic Diseases, Careggi University Hospital, Firenze; ³Department of Biomedical and Clinical Sciences, University of Milan; ⁴NEUROFARBA Department, Neuroscience Section, University of Firenze; ⁵Stroke Unit, Careggi University Hospital, Firenze; ⁶Neuroradiology Unit, Careggi University Hospital, Department of Experimental and Clinical Biomedical Sciences, University of Firenze, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.229

  720

  PDF: 23
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  Association between non-O blood type and early unexplained recurrent spontaneous abortion in women with and without inherited thrombophilia

  Anna Poretto, Elisabetta Borella, Giacomo Turatti, Michelangelo Marobin, Elena Campello, Daniela Tormene, Paolo Simioni, Luca Spiezia

  14-11-2022

  https://doi.org/10.4081/btvb.2022.47

  2942

  PDF: 452

• CO-32 | TRAUMA MANAGEMENT IN SEVERE HEMOPHILIA A: A CASE REPORT J. Di Paolo, R. Malizia, M. Luongo, P. Massaro, M. Di Mascio, S. Verna | Immunohematology Service, ASL 02 Abruzzo, Chieti, Italy

  Josephine Di Paolo

  14-10-2026

  https://doi.org/10.4081/btvb.2026.642

  17

  PDF: 5
• 

  PO68 | RISK OF VENOUS THROMBOEMBOLISM IN PATIENTS WITH CANCER AND MIGRAINE: A COHORT ANALYSIS AMONG DANISH NATIONAL HEALTH SURVEY PARTICIPANTS O. Rosenkrantz¹, P. Szentkúti¹, L. Amdisen¹, E. Horváth-Puhó¹, A.L. Pedersen¹, H.E. Bøtker², H. Elser^1|3, J.P. Vandenbroucke^1|4|5, H.T. Sørensen¹ | ¹Department of Clinical Epidemiology and Center for Population Medicine, Aarhus University Hospital and Aarhus University, Denmark; ²Department of Cardiology, Aarhus University Hospital, Department of Clinical Medicine, University of Aarhus, Denmark; ³Department of Neurology, Hospital of the University of Pennsylvania, Philadelphia, PA, USA; ⁴Department of Clinical Epidemiology, Leiden University Medical School Leiden, The Netherlands; ⁵School of Hygiene and Tropical Medicine, London, UK

  ICTHIC 2026

  16-04-2026

  https://doi.org/10.4081/btvb.2026.557

  509

  PDF: 109
• 

  Vasculopathy: a possible factor affecting hereditary angioedema

  Anna Laura Colia, Alessandra Ranaldi, Rosa Santacroce, Giovanna D'Andrea, Angela Bruna Maffione, Maurizio Margaglione, Maria D'Apolito

  04-02-2025

  https://doi.org/10.4081/btvb.2025.152

  1231

  pdf: 390
• 

  PO05 | DESIGN, SYNTHESIS, AND BIOLOGICAL EVALUATION OF NOVEL IMATINIB AND NILOTINIB ANALOGUES EXPRESSING ENHANCED ANTIPLATELET AND ANTICANCER ACTIVITIES D. Pantazi¹, L. Pechlivani¹, A. Kosma¹, K. Lalechou¹, M.G. Siskos², D. Alivertis³, A.D. Tselepis¹ | ¹Atherothrombosis Research Centre, Laboratory of Biochemistry, Department of Chemistry, University of Ioannina, Greece; ²Laboratory of Organic Chemistry, Department of Chemistry, University of Ioannina, Greece; ³Department of Biological Applications and Technology, University of Ioannina, Greece

  ICTHIC 2026

  16-04-2026

  https://doi.org/10.4081/btvb.2026.501

  539

  PDF: 100

• PO58 | Gender differences in primary haemostasis A. Becchetti², M. Brambilla², M. Conti², D. Trabattoni², E. Tremoli³, M. Camera^1,2 | ¹Department of Pharmaceutical Sciences, Università degli Studi di Milano; ²Centro Cardiologico Monzino IRCCS, Milan; ³Maria Cecilia Hospital, Cotignola (RA), Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.327

  639

  PDF: 12

• CO36 | Inhibitor titer at diagnosis and clinical course in acquired hemophilia A: a single-center experience C. Simion, B. Stocco, E. Dalla Porta, E. Campello, G. Furlan, L. Spiezia, G. Saggiorato, F. Sartorello, E. Zanon, P. Simioni | Department of Medicine – DIMED, University of Padua, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.243

  576

  PDF: 30

• CO-42 | LONGITUDINAL THROMBIN GENERATION PROFILING IN A PATIENT WITH SEVERE HEMOPHILIA A DURING ANTITHROMBIN-LOWERING THERAPY, CANCER, AND MAJOR SURGERY C. Simion^1|2, C. Bulato¹, E. Campello^1|2, E. Zanon^1|2, B. Serena¹, S. Toffanin¹, P. Simioni^1|2 | ¹First Chair of Internal Medicine and Thrombotic and Haemorrhagic Diseases Unit, Department of Medicine, Padova University Hospital, Italy; ²Hemophilia Center, Padova University Hospital, Italy

  Chiara Simion

  14-10-2026

  https://doi.org/10.4081/btvb.2026.652

  20

  PDF: 4
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  Inflammation and hemostatic system: a selection of involved clinical disorders

  Francesco Marongiu, Antonella Mameli, Silvia Marongiu, Doris Barcellona

  28-08-2026

  https://doi.org/10.4081/btvb.2026.474

  360

  PDF: 130

• CS08 | A combination of two rapid immunoassays improves HIT diagnosis G. Ciarrocca Taranta¹, A. Rogolino², A. Bertelli¹, A. Sorrentino¹, M. Di Gioia², F. Cesari², B. Giusti^1,2, E. Sticchi^1,2, M. Berteotti^1,2, A.M. Gori^1,2, R. Marcucci^1,2 | ¹Department of Experimental and Clinical Medicine, University of Firenze; ²Atherothrombotic Disease Unit, Careggi University Hospital, Firenze, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.205

  700

  PDF: 14

• CO-74 | WHAT WOMEN ARE NOT ASKED A MODEL OF CARE FOR WOMEN AND GIRLS WITH BLEEDING DISORDERS S. Pancetti, A.C. Ferrini, E. Magnani, P. Pedrazzi, C. Biasoli | Osp. M.Bufalini, Cesena, Italy

  Saverio Pancetti

  14-10-2026

  https://doi.org/10.4081/btvb.2026.684

  21

  PDF: 7
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  PO42 | DIFFERENTIAL EXPRESSION OF HEMOSTATIC BIOMARKERS ACROSS CANCER TYPE AND DISEASE STAGE: A PROSPECTIVE ANALYSIS OF 4,292 PATIENTS FROM THE HYPERCAN STUDY P. Gómez-Rosas^1|2|, D. Romeo¹, S. Bolognini¹, C. Ticozzi¹, F. Schieppati¹, A. D’Alessio⁴, R. Labianca⁴, A. Falanga^1|5|6, M. Marchetti^1|5|6 | ¹Hospital Papa Giovanni XXIII, Bergamo, Italy; ²Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, the Netherlands; ³Hospital de Oncologia, Unidad Medica de Alta Especialidad (UMAE), Centro Medico Nacional Siglo XXI, Instituto Mexicano del Seguro Social (IMSS), Mexico City, Mexico; ⁴Fondazione ARTET Onlus, Bergamo, Italy; ⁵ERN EuroBloodNet; ⁶School of Medicine and Surgery, University of Milan Bicocca, Italy; *On Behalf Of The Hypercan Investigators

  ICTHIC 2026

  16-04-2026

  https://doi.org/10.4081/btvb.2026.536

  486

  PDF: 108

• PO06 | Extracellular vesicles profiles in patients with porto-sinusoidal vascular disease S. Toffanin¹, E. Campello¹, A. Zanetto², C. M. Radu¹, E. Pinto², K. Fernande², C. Bulato¹, B. Serena¹, L. Spiezia¹, P. Burra², M. Senzolo², P. Simioni¹ | ¹First Chair of Internal Medicine, Department of Medicine, University Hospital of Padua Medical School, Padua; ²Department of Surgery Oncology and Gastroenterology, Gastroenterology and Multivisceral Transplant Unit, University Hospital of Padua, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.268

  621

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• CO-53 | LIVER FIBROSIS, STEATOSIS AND SUBCLINICAL ATHEROSCLEROSIS IN PATIENTS WITH HEMOPHILIA: A CROSS-SECTIONAL STUDY C. Simion^1|2, B. Stocco^1|2, I. Condonato^1|2, E. Dalla Porta^1|2, A. Napolitano^1|2, E. Zanon^1|2, L. Fabris¹, L. Spiezia^1|2, P. Simioni^1|2 | ¹First Chair of Internal Medicine and Thrombotic and Haemorrhagic Diseases Unit, Department of Medicine, Padova University Hospital, Italy; ²Hemophilia Center, Padova University Hospital, Italy

  Chiara Simion

  14-10-2026

  https://doi.org/10.4081/btvb.2026.663

  22

  PDF: 10

• BEST-04 | MAJOR ORTHOPEDIC SURGERY WITH EMICIZUMAB: A SERIES OF 22 PATIENTS (40 PROCEDURES) WITH A MID-TERM FOLLOW-UP G. Daniele¹, C. Carulli¹, S. Linari², L. Pieri², G. Castaman² | ¹Clinica Ortopedica, Azienda Ospedaliero-Universitaria Careggi, Università degli Studi di Firenze, Italy; ²Centro Malattie Emorragiche e della Coagulazione, Azienda Ospedaliero-Universitaria Careggi, Firenze, Italy

  Giovanna Daniele

  14-10-2026

  https://doi.org/10.4081/btvb.2026.604

  63

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  OC09 | BLEEDING RISK ASSOCIATED WITH FACTOR XI MONOCLONAL ANTIBODIES IN COMBINATION WITH ASPIRIN IN HEALTHY VOLUNTEERS AND ORTHOPEDIC SURGERY PATIENTS: ANALYSIS FROM RECENT PHASE 1 AND PHASE 2 STUDIES A.P. Kithcart¹, M.E. Burczynski¹, P. Banerjee¹, M. Onisko¹, Y. Wang¹, K. Mohammadi¹, D. Li¹, S. Li¹, J. Ackroyd², B.A. Olenchock¹, D.E. Gutstein¹, J. I. Weitz³ | ¹Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA; ²Clinical Research, Fortrea Clinical Research Unit Ltd, Leeds, UK; ³McMaster University, Hamilton, ON, Canada

  ICTHIC 2026

  16-04-2026

  https://doi.org/10.4081/btvb.2026.492

  442

  PDF: 113

• PO45 | Routine prophylaxis with PD-FX concentrate in severe inherited FX deficiency: a case report S. Linari, L. Pieri, M. Attanasio, F. Salvianti, M. Coppo, E. Grisanti, F. Demartis, R. Fjerza, G. Castaman | Centre for Bleeding Disorders and Coagulation, Azienda Ospedaliera Universitaria Careggi, Firenze, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.308

  616

  PDF: 20

• CO21 | Viscoelastic testing in inherited bleeding disorders: a cross-sectional comparison between viscoelastic coagulation monitoring and rotational thromboelastometry C. Simion, C. Samà, C. Bulato, G. Gottardi, D. Regazzo, E. Campello, P. Simioni | Department of Medicine – DIMED, University of Padua, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.227

  639

  PDF: 17

• CO-81 | DIGITAL NETWORKING FOR ACQUIRED HEMOPHILIA A: A REGION-WIDE CARE PATHWAY FROM DIAGNOSIS TO FOLLOW-UP M. Mattana¹, M.F. Mansueto², S. Raso¹, S. Siragusa^2|3, R. Tomasello¹, M. Napolitano^1|3 | ¹A.O.O.R. Villa Sofia Cervello P.O. Cervello-UOC di Ematologia per le Malattie Rare del Sangue e degli Organi Ematopoietici, Palermo, Italy; ²UOC Ematologia Policlinico P.Giaccone Palermo, Italy; ³Dipartimento Promozione della Salute, Materno-Infantile, di Medicina Interna e Specialistica di Eccellenza(PROMISE), Università degli studi di Palermo, Italy

  Marta Mattana

  14-10-2026

  https://doi.org/10.4081/btvb.2026.691

  18

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  Still unmet problems with low molecular weight heparin prophylaxis of venous thromboembolism. An Italian survey

  Stefania Cavazza, Gualtiero Palareti*

  03-10-2025

  https://doi.org/10.4081/btvb.2025.177

  1443

  PDF: 303

  HTML: 201

  Supplementary: 102

• PO18 | Does muscle mass matter? Appendicular lean mass as a determinant of anti-XA activity in elderly patientes B.M. Zanforlini¹, V. Bernardi¹, E. Campello², E.M. Bicego¹, C. Curreri¹, A. Vaticano¹, C. Sartori¹, L. Manfron¹, A. Perencin¹, P. Rollo¹, A. Baruffol¹, L. Ruoso¹, C. Simion², C. Bulato², P. Berto², P. Simioni², G. Sergi¹ | ¹Department of Medicine, Geriatrics Section, University of Padova; ²Haemorrhagic and Thrombotic Diseases Unit, Department of Medicine DIMED, Padova University Hospital, Padova, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.278

  589

  PDF: 16
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  Venous thromboembolism prophylaxis in orthopedic surgery: a narrative review

  Sarah Gallitto, Thomas C. Varkey, Jacob Lahti

  13-12-2024

  https://doi.org/10.4081/btvb.2024.131

  3337

  PDF: 455

• CO-60 | A TURNING POINT IN THE MANAGEMENT OF HEMOPHILIA B WITH INHIBITORS: OUTCOMES OF CONCIZUMAB PROPHYLAXIS IN TWO CHILDREN FROM EXPLORER10 G. Quintavalle¹, A. Matichecchia¹, M.I. Tassoni¹, B.M. Roccon¹, F. Riccardi¹, R.P. Serra², A. Tiri², P. Bertolini², A. Tagliaferri¹, A. Coppola¹ | ¹Regional Hub Center for Hemophilia and Congenital Bleeding Disorders, University Hospital of Parma, Italy; ²Pediatric Hematology-Oncology Unit, University Hospital of Parma, Italy

  Antonio Coppola

  14-10-2026

  https://doi.org/10.4081/btvb.2026.670

  20

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  PO04 | FIBRIN CLOT SHIELDS PROMOTE CLONAL SELECTION IN CANCER CELLS: PROCOAGULANT ACTIVITY AND SURVIVAL OF CLOT-EMBEDDED CELLS. A NOVEL TUMOR MICROENVIRONMENT MODEL M.A. Baghdadi^1|2, E. Mbemba¹, P. Las Casa¹, P. Van Dreden^1|3, N. Saleem^1|4, J. Fareed⁴, P. Kempaiah⁴, M. Sabbah¹, G. Gerotziafas^1|4 | ¹Sorbonne University, INSERM UMR_S_938, CRSA, Research Department "Cancer, Vessels, Biology and Therapeutics" (CaVITE), Research Group "Cancer-Angiogenesis-Thrombosis and Haemostasis," Thrombosis Center, University Institute of Cancerology, Saint Antoine University Hospital Assistance Publique Hôpitaux de Paris (AP-HP) Paris, France; ²Research Center, King Faisal Specialist Hospital and Research Center, Jeddah, Saudi Arabia; ³Diagnostica Stago, Gennevilliers, France; ⁴Center of Translational Research and Education, Department of Pathology and Laboratory Medicine, Loyola University Stritch School of Medicine, Maywood, Ill., USA

  ICTHIC 2026

  16-04-2026

  https://doi.org/10.4081/btvb.2026.500

  462

  PDF: 91

• PO57 | Direct oral anticoagulant determination in urine samples compared to plasma concentrations in outpatients with atrial fibrillation and obesity A. Pannunzio¹, I.M. Palumbo¹, D. Menichelli¹, V. Cammisotto², V. Castellani³, E. Baldacci⁴, R. Mormile⁴, A. Chistolini⁴, G. Bernardini⁵, N. Porcu¹, D. Pastori², J. Harenberg⁶, F. Violi², P. Pignatelli² | ¹Department of General Surgery, Surgical Specialties and Organ Transplantation Paride Stefanini, Sapienza University of Roma, Italy; ²Department of Clinical Internal, Anesthesiological and Cardiovascular Sciences, Sapienza University of Roma, Italy; ³Department of Translational and Precision Medicine, Sapienza University of Roma, Italy; ⁴Department of Hematology, Oncology and Dermatology, Sapienza University of Roma, Italy; ⁵U.O.S.D. Medicina Rigenerativa DAI, Medicina Diagnostica e Radiologia, Policlinico Umberto 1, Roma, Italy; ⁶Ruprecht Karls University of Heidelberg, Germany

  22-10-2025

  https://doi.org/10.4081/btvb.2025.326

  543

  PDF: 16

• CO34 | Evaluation of emicizumab concentration and thrombin generation in a cohort of severe hemophilia A patients with and without inhibitor A. Taglietti¹, S. Ligia¹, F. Paoletti¹, R. Mormile¹, E. Baldacci², A. Chistolini¹, C. Santoro^1,2 | ¹Hematology, Department of Translational and Precision Medicine, Sapienza University of Roma; ²Hematology, Azienda Ospedaliera Universitaria Policlinico Umberto I, Roma, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.241

  665

  PDF: 11

• CS07 | Endothelial dysfunction and impaired angiogenesis in Hermansky-Pudlak syndrome (HPS) type 1: studies with endothelial colony forming cells F. Tondi¹, G. Purgatorio¹, C. Sgromo², E. Giglio¹, E. Petito¹, E. Falcinelli¹, G. Guglielmini¹, A. Follenzi², P. Gresele¹, L. Bury^1*, C. Olgasi^3* | ^*Shared senior authorship; ¹Department of Medicine and Surgery, Section of Internal and Cardiovascular Medicine, University of Perugia; ²Department of Health Sciences, School of Medicine, University of Piemonte Orientale, Novara; ³Department of Translational Medicine, School of Medicine, University of Piemonte Orientale, Novara, Italy

  16-09-2025

  https://doi.org/10.4081/btvb.2025.204

  283

• CO-22 | CLINICAL FEATURES IN PATIENTS WITH NON-SEVERE HEMOPHILIA A: THE DISCOVERY SCORE PROPOSAL FOR PROPHYLAXIS PRESCRIPTION M.N.D. Di Minno¹, E. Baldacci², C. Biasoli³, A. Borchiellini⁴, F. Daniele⁵, P. Di Gregorio⁶, C. Gorio⁷, G. Malcangi⁸, E. Marchesini⁹, I. Ricca¹⁰, R. Santoro¹¹, S. Siragusa¹², M.R. Villa¹³, E. Zanon¹⁴, A. Tagliaferri¹⁵, A. Coppola¹⁵ | ¹Hub Centre for Thrombotic and Hemorrhagic Disorders, Federico II University Hospital, Napoli, Italy; ²Haematology, University Hospital Policlinico Umberto I, Roma, Italy; ³Interdepartmental Simple Structure for the Management of Hemorrhagic and Thromboembolic Diseases, M. Bufalini Hospital, Cesena, Italy; ⁴Regional Centre for Hemorrhagic and Thrombotic Diseases, AOU Città della Salute e della Scienza, Torino, Italy; ⁵Haemostasis and Thrombosis Service, Ospedale Civile dell'Annunziata, Cosenza, Italy; ⁶Transfusion Medicine Department, "SS. Annunziata" Hospital, Chieti, Italy; ⁷Pediatric Onco-Hematology Unit, Children's Hospital, ASST-Spedali Civili, Brescia, Italy; ⁸Haemophilia and Thrombosis Center, University Hospital Policlinico-Giovanni XXIII, Bari, Italy; ⁹Hemophilia Centre, SC Vascular and Emergency Department, University of Perugia, Italy; ¹⁰Centro Emofilia, Città della Salute e della Scienza, Torino, Italy; ¹¹Hemostasis and Thrombosis Unit, Azienda Ospedaliero Universitaria Dulbecco, Catanzaro, Italy; ¹²Centro di Riferimento Regionale per le Emocoagulopatie Congenite, Palermo, Italy; ¹³Hematology Unit, Ospedale Santa Maria di Loreto, Napoli, Italy; ¹⁴Hemophilia and Thrombosis Center, University Hospital of Padua, Italy; ¹⁵Hemophilia and Thrombosis Center, Azienda Ospedaliera di Parma, Italy

  Matteo Di Minno

  14-10-2026

  https://doi.org/10.4081/btvb.2026.632

  29

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  PO41 | VENOUS THROMBOEMBOLISM IN PERIPHERAL BLOOD STEM CELL COLLECTION. A SINGLE CENTER EXPERIENCE P. Holly¹, J. Hudecek¹, J. Chudej¹, L. Valekova¹, I. Plamenova¹, E. Flochova¹, R. Simonova¹, J. Sokol¹, J. Stasko¹, M. Pietrzykova^1|2, E. Vescecikova² | ¹Department of Hematology and Transfusion Medicine, University Hospital in Martin, Martin, Slovakia; ²National Transfusion Service, Martin, Slovakia

  ICTHIC 2026

  16-04-2026

  https://doi.org/10.4081/btvb.2026.535

  500

  PDF: 102

• PO05 | Intensive FVIII replacement in haemophilia patients with hypertrophic synovium: a randomized study I.L. Calcaterra¹, E. Baldacci², R. Marino³, F. Valeri⁴, R.C. Santoro⁵, G. Pasta⁶, C. Martinoli⁷, M. Di Minno¹ | ¹Department of Clinical Medicine and Surgery, Federico II University, Naples; ²Haematology, University Hospital Policlinico Umberto I, Roma; ³Haemophilia Center and thrombosis, Policlinico, Bari; ⁴Regional Centre for Haemorrhagic and Thrombotic Diseases, AOU Città Della Salute e Della Scienza; Turin; ⁵Centre for Hemorrhagic and Thrombotic Disorders, Pugliese Ciaccio Hospital, Catanzaro; ⁶Fondazione IRCCS San Matteo Hospital, Pavia; ⁷Department of Health Science DISSAL, University of Genoa, Unit of Radiology and IRCCS San Martino Hospital, Genoa, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.267

  590

  PDF: 17
• 

  Influence of emicizumab on protein C-mediated clotting regulation

  Federica Mancazzo, Antonia Vitulli, Lavinia Dirienzo, Concetta T. Ammollo, Fabrizio Semeraro, Mario Colucci

  25-10-2023

  https://doi.org/10.4081/btvb.2023.89

  2644

  PDF: 438

  Supplementary Material: 136

• BEST-03 | CRISPR-CAS9 CORRECTION IN SEVERE HEMOPHILIA A A. Benetti¹, C.M. Radu¹, M. Trevisan², C. Samà¹, C. Simion¹, E. Campello¹, P. Simioni¹ | ¹First Chair of Internal Medicine and Thrombotic and Haemorrhagic Diseases Unit, Department of Medicine, Padova University Hospital, Italy; ²Department of Molecular Medicine, University of Padua, Italy

  Andrea Benetti

  14-10-2026

  https://doi.org/10.4081/btvb.2026.603

  60

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  OC04 | DIRECT ORAL ANTICOAGULANTS PROVIDE EFFECTIVE THROMBOPROPHYLAXIS IN NEWLY DIAGNOSED MYELOMA: REAL WORLD FINDINGS FROM THE ATOMM STUDY T. Bull¹, Heamstar Collaborators², W. Wilson³, E. Ganendra⁴, M. Thomas⁵, R. Alikhan⁶, M. Karanth¹, M. Camilleri⁷ | ¹West Suffolk Hospital NHS Foundation Trust, UK; ²Haematology Specialty Training Audit and Research HaemSTAR Network, UK; ³University College London Clinical Trial Centre, UK; ⁴North West Anglia NHS Foundation Trust, UK; ⁵University College London Hospitals, UK; ⁶Cardiff and Vale University Health Board, Wales, UK; ⁷Cambridge University Hospitals NHS Foundation Trust, UK

  ICTHIC 2026

  16-04-2026

  https://doi.org/10.4081/btvb.2026.488

  604

  PDF: 132
• 

  Vaccine-induced immune thrombotic thrombocytopenia following ChAdOx1 nCoV-19 vaccine: report of two cases

  Rita Carlotta Santoro, Roberto Minici, Marzia Leotta, Mariapia Falbo, Lucia Concetta Elia, Francesca Leo, Antonella Ierardi, Alessandra Strangio, Simona Prejanò

  23-05-2022

  https://doi.org/10.4081/btvb.2022.23

  4520

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  PO64 | MANAGEMENT OF BLEEDING RISK IN PATIENTS WITH HEPATOCELLULAR CARCINOMA RECEIVING SYSTEMIC THERAPY: A SURVEY OF CLINICAL PRACTICE T. Van Broeckhoven^1|9, E. Van Gansewinkel^5|10, J. De Bruijne², F. Eskens³, D. De Groot⁴, K. Hermans⁵, N. Mohammad⁶, F. Van Vilsteren⁷, C. Verslype⁸, W. Moris⁹, M. Roest¹⁰, B. De Laat¹⁰ , J. De Vos-Geelen⁵, M. Kramer^1|9 | ¹Department of Gastroenterology and Hepatology, GROW – Research Institute for Oncology and Reproduction, Maastricht University Medical Center, Maastricht, The Netherlands; ²Department of Gastroenterology & Hepatology, Utrecht University, University Medical Center Utrecht, The Netherlands; ³Department of Medical Oncology, Erasmus Medical Centre, Rotterdam, the Netherlands; ⁴Department of Medical Oncology, University Medical Centre Groningen, University of Groningen, the Netherlands; ⁵Department of Internal Medicine, Division of Medical Oncology, GROW – Research Institute for Oncology & Reproduction, Maastricht University Medical Center, Maastricht, The Netherlands; ⁶Department of Medical Oncology, University Medical Centre Utrecht, Utrecht University, Utrecht, the Netherlands; ⁷Department of Gastroenterology and Hepatology, University Medical Centre Groningen, Groningen, The Netherlands; ⁸Digestive Oncology, University Hospitals Leuven, Belgium; ⁹Department of Gastroenterology and Hepatology, Maastricht University Medical Center, Maastricht, The Netherlands; ¹⁰Department of Functional Coagulation, Synapse Research Institute, Maastricht, The Netherlands, on behalf of the Dutch Hepatocellular & Cholangiocarcinoma Group

  ICTHIC 2026

  16-04-2026

  https://doi.org/10.4081/btvb.2026.554

  436

  PDF: 95

• PO14 | Searching for safer rescue immunosuppressive therapy protocols in acquired hemophilia A: two case reports G. Quintavalle¹, I.M. Tassoni¹, B.M. Roccon¹, G. Lucchini², F. Magalini², M. Zardo², R. Rossi³, C. Cattabiani³, A. Tagliaferri¹, A. Coppola¹ | ¹SSD Centro HUB Emofilia e MEC; ²UOS Medicina Interna e Reumatologia; ³UO Diagnostica Ematochimica, Azienda Ospedaliero Universitaria, Parma, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.275

  548

  PDF: 17
• 

  The evolving landscape of gene therapy for congenital severe hemophilia: a 2024 state of the art

  Giovanni Di Minno, Gaia Spadarella, Ilenia Lorenza Calcaterra, Giancarlo Castaman, Paolo Simioni, Raimondo De Cristofaro, Cristina Santoro, Flora Peyvandi, Matteo Di Minno

  04-09-2024

  https://doi.org/10.4081/btvb.2024.144

  2074

  PDF: 359

  SUPPLEMENTARY MATERIAL: 217

• CO33 | Acquired hemophilia A in Liguria, Italy: what six years of data reveal C. Vernarecci¹, A. C. Molinari¹, P. Ballarino², M. Caiti², E. Cenni², P. Moscatelli², L. Banov¹ | ¹IRCCS Istituto Giannina Gaslini, Genova; ²IRCCS Policlinico San Martino, Genova, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.240

  605

  PDF: 28
• 

  Development of a shared decision-making tool for gene therapy in hemophilia A in Italy

  Giovanni Di Minno, Sarah Bigi, Serena Barello, Enrico Ferri Grazzi, Marco Follino, Maria Francesca Mansueto, Mariasanta Napolitano, Rita Carlotta Santoro, Giancarlo Castaman

  22-06-2026

  https://doi.org/10.4081/btvb.2026.426

  916

  PDF: 131

  SUPPLEMENTARY MATERIAL: 78
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  Executive summary of the SISET position paper on the management of antithrombotic therapy in left ventricular thrombus

  Emanuele Valeriani, Arianna Pannunzio, Danilo Menichelli, Domenico Prisco, Walter Ageno, Daniele Pastori, Pasquale Pignatelli

  16-12-2025

  https://doi.org/10.4081/btvb.2025.401

  452

  PDF: 131

  HTML: 110

• CS06 | Patient specific iPSCs-derived sinusoidal endothelial cells for phenotypic correction of haemophilia A A. Benetti¹, C.M. Radu¹, C. Samà¹, M. Trevisan², C. Simion¹, E. Campello¹, P. Simioni¹ | ¹Department of Medicine - DIMED, Padua University Hospital; ²Department of Molecular Medicine, University of Padua, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.203

  720

  PDF: 20

• CO52 | The impact of KRAS mutations on the risk of recurrent venous thromboembolism in patients with cancer-associated thrombosis and gastrointestinal neoplasms B. Cosmi^1,2, S. Cavara², M. Soldati², L. Borgese², M. Sartori² | ¹Angiology and Blood Coagulation Unit, Department of Medical and Surgical Sciences, University of Bologna; ²Angiology and Blood Coagulation Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.262

  606

  PDF: 29
• 

  Inherited platelet function disorders: a comprehensive narrative review focusing on diagnostic and management aspects

  Antonietta Ferretti, Nicola Portesi, Chiara Gorio, Marzia Leotta, Alessandra Strangio, Antonella Ierardi, Bianca Maria Roccon, Giulia Albrici, Giulia Carracchia, Marta Mattana, Chiara Biasoli, Cristina Santoro, Tiziano Martini, Rita Carlotta Santoro

  21-10-2026

  https://doi.org/10.4081/btvb.2026.581

  8

  PDF: 5

  SUPPLEMENTARY MATERIAL: 0

• CO-49 | JOINT STATUS EVALUATION BY ULTRASOUND AND FUNCTIONAL ASSESSMENT IN PERSONS WITH NON SEVERE HEMOPHILIA ON PROPHYLAXIS WITH FOCUS ON THOSE WITH 5-YR FOLLOW UP G. Quintavalle¹, M.I. Tassoni¹, B.M. Roccon¹, G.F. Rivolta¹, C. Costantino², R.M. Polo³, A. Matichecchia¹, A. Tagliaferri¹, A. Coppola¹ | ¹SSD Centro Hub Emofilia e Malattie Emorragiche Congenite, Az. Ospedaliero-Universitaria di Parma, Italy; ²SSD Riabilitazione Ambulatoriale e Ortogeriatrica, Az. Ospedaliero-Universitaria di Parma, Italy; ³Clinica Ortopedica, Az. Ospedaliero-Universitaria di Parma, Italy

  Gabriele Quintavalle

  14-10-2026

  https://doi.org/10.4081/btvb.2026.659

  17

  PDF: 7
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  Preface to the 13^th International Conference on Thrombosis and Hemostasis Issues in Cancer, 2026

  Anna Falanga, Benjamin Brenner, Alok A. Khorana

  16-04-2026

  https://doi.org/10.4081/btvb.2026.479

  869

  PDF: 227
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  Milvexian and other drugs targeting Factor XI: a new era of anticoagulation?

  Marco P. Donadini, Walter Ageno

  15-04-2022

  https://doi.org/10.4081/btvb.2022.22

  2522

  PDF: 765
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  PO53 | PHASE 3 TRIAL EVALUATING THE EFFICACY AND SAFETY OF REGN7508^CAT FOR PRIMARY PROPHYLAXIS OF CANCER-ASSOCIATED THROMBOSIS FOR PARTICIPANTS WITH SOLID TUMORS UNDERGOING CANCER TREATMENT (ROXI-CAT-I) J. Zwicker¹, M. P. O’Brien², M. Carrier³, J. Connors⁴, A. Falanga⁵, A. Manzano⁶, R. Mcbane⁷, Y.Y. Janjigian¹, G. O’Kane⁸, M. Onisko², J. Kaplan², A.P. Kithcart², D.E. Gutstein², A. Khorana⁹, M. F. Walsh² | ¹Memorial Sloan Kettering Cancer Center, New York, USA; ²Regeneron Pharmaceuticals, Inc. , Tarrytown, NY, USA; ³University of Ottawa, Ottawa, ON, Canada; ⁴Harvard Medical School, Boston, MA, USA; ⁵Hospital Papa Giovanni XXIII, Bergamo, Italy; ⁶Hospital Universitario 12 de Octubre, Madrid, Spain; ⁷Mayo Clinic, Rochester, MN, USA; ⁸St. Vincent's University Hospital and School of Medicine, University College Dublin, Dublin, Ireland; ⁹James P. Wilmot Cancer Center and the Department of Medicine, University of Rochester, Rochester, NY, USA

  ICTHIC 2026

  16-04-2026

  https://doi.org/10.4081/btvb.2026.545

  496

  PDF: 122

• PO12 | Characterisation and real word clinical data of HEM006, a newly formulated intranasal spray desmopressin (DDAVP) to address a global treatment gap G. De Giorgi¹, A. Gringeri², R. Franceschini¹, A. Koganti³ | ¹Hemorare Srl, Italy; ²Fondazione Charta, Milan, Italy; ³Quenya LLC, USA

  22-10-2025

  https://doi.org/10.4081/btvb.2025.274

  568

  PDF: 12

• BEST-09 | IMMUNOGENIC IMPLICATIONS OF TRANSLATIONAL READTHROUGH MODULATE THE ASSOCIATION OF F8 NONSENSE MUTATIONS WITH INHIBITORS IN HEMOPHILIA A D. Balestra¹, M.F. Testa¹, M. Pinotti¹, A. Branchini¹, M.E. Mancuso², F. Bernardi¹ | ¹Department of Life Sciences and Biotechnology and LTTA Center, University of Ferrara, Italy; ²IRCCS, Humanitas Research Hospital, Center for Thrombosis and Hemorrhagic diseases, Milano, Italy

  Dario Balestra

  14-10-2026

  https://doi.org/10.4081/btvb.2026.609

  63

  PDF: 7
• 

  PO02 | SYNERGISTIC INTERACTION OF ENDOTHELIAL AND CANCER CELLS IN THE FORMATION AND STRUCTURE OF THE FIBRIN CLOT SHIELDS M.A. Baghdadi^1|2, E. Mbemba¹, P. Las Casa¹, P. Van Dreden^1|3, N. Saleem^1|4, J. Fareed⁴, P. Kempaiah⁴, M. Sabbah¹, G. Gerotziafas^1|4 | ¹Sorbonne University, INSERM UMR_S_938, CRSA, Research Department "Cancer, Vessels, Biology and Therapeutics" (CaVITE), Research Group "Cancer-Angiogenesis-Thrombosis and Haemostasis," Thrombosis Center, University Institute of Cancerology (UIC), Saint Antoine University Hospital Assistance Publique Hôpitaux de Paris (AP-HP) Paris France; ²Research Center, King Faisal Specialist Hospital and Research Center, Jeddah, Saudi Arabia; ³Diagnostica Stago, clinical research, Gennevilliers, France; ⁴Center of Translational Research and Education, Department of Pathology and Laboratory Medicine, Loyola University Stritch School of Medicine, Maywood, Ill., USA

  ICTHIC 2026

  16-04-2026

  https://doi.org/10.4081/btvb.2026.498

  451

  PDF: 95

• CO32 | Major surgery in patients with severe hemophilia A without inhibitors receiving prophylaxis with fitusiran E. Zanon, C. Simion, A. Napolitano, L. Spiezia, P. Simioni | Haemophilia Center, First Chair of Internal Medicine, Department of Medicine, University-Hospital of Padua Medical School, Padua, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.239

  554

  PDF: 21

• CO-85 | ACQUIRED HEMOPHILIA A IN LIVER CIRRHOSIS: BALANCING HEMOSTASIS BETWEEN HIGH HEMORRHAGIC AND THROMBOTIC RISKS N. Portesi, G. Martini | ASST Spedali Civili di Brescia, Italy

  Nicola Portesi

  14-10-2026

  https://doi.org/10.4081/btvb.2026.695

  21

  PDF: 12

• CS02 | Functional and structural impairments of the cerebral microcirculation in a mouse model of hemophilia A G. Venturin¹, C. Olgasi², C. Borsotti¹, P.E. Di Simone¹, E. Spicuglia¹ A. Cucci¹, C. Sgromo¹, A. Follenzi^2,3 | ¹Department of Health Science, Università del Piemonte Orientale, Novara; ²Department of Translational Medicine, Università del Piemonte Orientale, Novara; ³Department of Attività Integrate Ricerca Innovazione, Azienda Ospedaliero-Universitaria SS. Antonio e Biagio e C. Arrigo, Alessandria, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.197

  740

  PDF: 20

• CO-19 | A CASE OF LOSS OF EFFICACY OF EMICIZUMAB AFTER 6 YEARS OF REGULAR USE M.R. Fasulo¹, I. Quaglia¹, A. Colombo¹, C. Lodigiani¹, M.E. Mancuso^1|2 | ¹Center for Thrombosis and Hemorrhagic Diseases, IRCCS Humanitas Research Hospital, Rozzano, Milano, Italy; ²Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milano, Italy

  Maria Rosaria Fasulo

  14-10-2026

  https://doi.org/10.4081/btvb.2026.629

  20

  PDF: 7
• 

  PO19 | THE INTER-RELATIONSHIP BETWEEN NETOSIS, THE ADAMTS-13/VWF AXIS, AND HEMOSTATIC ACTIVATION IN PATIENTS WITH GYNECOLOGICAL MALIGNANCIES: PROGNOSTIC SIGNIFICANCE AND IMPACT OF CHEMOTHERAPY A. Makatsariya¹, E. Beloborodova²,V. Bitsadze¹, J. Khizroeva¹, A. Vorobev¹, A. Solopova¹, M. Tretyakova¹, N. Gashimova¹, K. Grigoreva¹, A. Oskolkova¹, J. Christophe Gris^1|3, I. Elalamy^1|4|5, G. Gerotziafas^1|4|5 | ¹Department of Obstetrics, Gynecology and Perinatal Medicine, N. F. Filatov Clinical Institute of Children’s Health, I. M. Sechenov First Moscow State Medical University Sechenov University, Moscow, Russia; ²MEDSI Network of Medical Centers, Moscow, Russia; ³Faculty of Pharmaceutical and Biological Sciences, Montpellier University, France; ⁴Department Hematology and Thrombosis Center, Medicine Sorbonne University, Paris, France; ⁵Hospital Tenon, Paris, France

  ICTHIC 2026

  16-04-2026

  https://doi.org/10.4081/btvb.2026.514

  457

  PDF: 93

• PO68 | Whole blood hypercoagulable profiles in a patient with markedly elevated lipoprotein(A) plasma levels and thrombotic complications: a case report C. Portinari, M. Biolo, A. Napolitano, L. Spiezia, A. Colpo, S. Zambon, A. Zambon, P. Simioni | Department of Medicine, Padova University Hospital, Padova, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.337

  637

  PDF: 26
• 

  It’s definitely time to consider diet in its ultra-processing form as a major risk factor for thrombotic vascular disorders

  Marialaura Bonaccio, Licia Iacoviello, Maria Benedetta Donati

  03-08-2023

  https://doi.org/10.4081/btvb.2023.91

  1824

  PDF: 573

• BEST-01 | IDENTIFICATION OF NOVEL HYPERACTIVE rFVIIa BYPASSING MOLECULES INFERRED BY ANCESTRAL SEQUENCE RECONSTRUCTION APPROACH M.F. Testa, I. Passerini, P. Santos, A. Benazzo, S. Ghirotto, F. Bernardi, A. Branchini, M. Pinotti, D. Balestra | Dep. of LSB, University of Ferrara, Italy

  Maria Francesca Testa

  14-10-2026

  https://doi.org/10.4081/btvb.2026.601

  63

  PDF: 12
• 

  Anticoagulation during anti-angiogenic cancer therapy: balancing risks of thrombosis and bleeding

  Nikola Vladic, Florian Moik

  16-04-2026

  https://doi.org/10.4081/btvb.2026.452

  293

  PDF: 172

• PO42 | Acquired Von Willebrad syndrome in patients with myeloproliferative syndrome: literature review and single-center experience A. Strangio, M. Leotta, A. Ierardi, R C. Santoro | UO Emofilia, Emostasi e Trombosi, AOU R Dulbecco, Catanzaro, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.305

  545

  PDF: 22

• CO12 | Left internal carotid artery thrombosis in a patient with antiphospholipid antibody syndrome successfully treated with eculizumab A. Hoxha¹, L. Nico², F. Viaro³, L. Fabris¹, Y.F. Herrera¹, M. Munari⁴, C. Baracchini³, F. Causin², P. Simioni¹ | ¹Internal Medicine Unit, Thrombotic and Haemorrhagic Centre, Department of Medicine - DIMED, University of Padua; ²Neuradiology Unit, University Hospital of Padua; ³Stroke Unit, Neurology Department, University of Padua; ⁴Intensive Care Unit, University Hospital of Padua, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.216

  675

  PDF: 21
• 

  An ecological alliance against air pollution and cardiovascular disease

  Pier Mannuccio Mannucci

  22-03-2022

  https://doi.org/10.4081/btvb.2022.21

  2154

  PDF: 493

• PO94 | The use of antidepressant drugs and benzodiazepine hypnotics as an unusual risk factor for VTE G. Chiarelli, F. Strano, P. Conca, P. Rufolo, M. G. Mazzone, R. Russo, L. Jr Valletta, G. D’Errico, C. De Luca, E. Cimino, A. Tufano, M.N.D. Di Minno | Department of Clinical Medicine and Surgery, Federico II University of Naples, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.364

  737

  PDF: 21

• PO11 | Neutrophil cathepsin G and risk of cardiovascular events in patients with diabetes mellitus V. Cammisotto¹, F. Baratta², S. Bartimoccia³, D. Pastori¹, N. Cocomello⁴, V. Castellani⁵, C. Nocella¹, R. Carnevale³, G. Desideri¹, F. Violi¹, P. Pignatelli¹ | ¹Department of Clinical, Internal Medicine, Anesthesiological and Cardiovascular Sciences, Sapienza University of Roma; ²Geriatric Unit, Department of Internal Medicine and Medical Specialties, AOU Policlinico Umberto I, Roma; ³Department of Medical-Surgical Sciences and Biotechnologies, Sapienza University of Roma; ⁴Department of Anatomical Sciences, Histological, Legal Medical and Locomotor, Sapienza University of Roma; ⁵Department of Experimental Medicine, Sapienza University of Roma, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.273

  590

  PDF: 20

• PO46 | Intravitreal treatment with faricimab in patients with age-related macular degeneration M. Alfonsetti¹, R. Liani¹, P.G.M. Simeone¹, M. Frezza¹, A. Ricci³, S. Lattanzio¹, R. D’Aloisio², L. Toto², F. Santilli¹ | ¹Department of Medicine and Aging, Center for Advanced Studies and Technology “CAST”; ²Ophthalmology Clinic, Department of Medicine and Aging; ³Department of Pharmacy, University “G. d’Annunzio” of Chieti Pescara, Chieti, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.315

  474

  PDF: 15

• CO30 | Joint prosthetic surgery in patients with hemophilia A: clinical-functional outcomes and quality of life E. Zanon¹, A. Napolitano¹, A. Berizzi², P. Simioni¹ | ¹Haemophilia Center, First Chair of Internal Medicine, Department of Medicine, University-Hospital of Padua Medical School, Padua; ²Orthopedics and Traumatology Unit, University-Hospital of Padua Medical School, Padua, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.236

  686

  PDF: 31