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• CO113 | AN OBSERVATIONAL STUDY ON THE EFFECT OF HEMODIALYSIS MEMBRANES ON ENDOGENOUS THROMBIN POTENTIAL IN END-STAGE RENAL DISEASE PATIENTS Z. Saeed^1|4, O. Ndrecka², V. Sirolli², M. Bonomini², P. Lanuti^1|3, S. Gallina⁴, G. Rend^1|4 | ¹Center for Advanced Studies and Technology, G. d’Annunzio University of Chieti-Pescara, Chieti, Italy; ²Nephrology and Dialysis Unit, Department of Medicine, G. d’Annunzio University of Chieti-Pescara, SS. Annunziata Hospital, Chieti, Italy; ³Department of Medicine and Aging Sciences, G. d’Annunzio University of Chieti-Pescara, Chieti, Italy; ⁴Department of Neuroscience, Imaging and Clinical Sciences, G. d’Annunzio University of Chieti-Pescara, Chieti, Italy

  Zeeba Saeed

  26-10-2026

  https://doi.org/10.4081/btvb.2026.815

  7

  PDF: 2

• CO083 | IN VITRO CORRECTION OF SEVERE FACTOR V DEFICIENCY USING A NOVEL PLASMA-DERIVED FV CONCENTRATE: A WHOLE BLOOD THROMBIN GENERATION STUDY C. Bulato¹, L. Spiezia¹, E. Campello¹, B. Serena¹, S. Toffanin¹, C. Simion¹, A. Caricasole², M. Sotgiu², A. Salvatore², F. Pierantoni², T.M. Hackeng^3|4, H.M.H. Spronk^3|4, P. Simioni¹ | ¹Thrombotic and Hemorrhagic Diseases Unit, General Internal Medicine, Department of Medicine, Padova University Hospital, Italy; ²Kedrion SpA, Barga Lucca, Italy; ³Coagulation Profile B.V., Maastricht, the Netherlands; ⁴Department of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht University, the Netherlands

  Cristiana Bulato

  26-10-2026

  https://doi.org/10.4081/btvb.2026.785

  5

  PDF: 2

• CO-42 | LONGITUDINAL THROMBIN GENERATION PROFILING IN A PATIENT WITH SEVERE HEMOPHILIA A DURING ANTITHROMBIN-LOWERING THERAPY, CANCER, AND MAJOR SURGERY C. Simion^1|2, C. Bulato¹, E. Campello^1|2, E. Zanon^1|2, B. Serena¹, S. Toffanin¹, P. Simioni^1|2 | ¹First Chair of Internal Medicine and Thrombotic and Haemorrhagic Diseases Unit, Department of Medicine, Padova University Hospital, Italy; ²Hemophilia Center, Padova University Hospital, Italy

  Chiara Simion

  14-10-2026

  https://doi.org/10.4081/btvb.2026.652

  23

  PDF: 9

• CO-36 | PLATELETS MATTER: THROMBIN GENERATION IN PLATELET‐RICH-PLASMA VS. PLATELET‐POOR‐PLASMA UNDER NON-REPLACEMENT THERAPIES IN HEMOPHILIA F. Bocchi^1|2, R. Pastorino^1|2, G. Murante^1|2|3, S. Bergonzi^1|2|3, M. Capetta^1|2|3, F. Valeri^2|3, C. Dainese^2|3, A. Valpreda⁴, B. Bruno^1|3, A. Borchiellini^2|3 | ¹Department of Molecular Biotechnology and Health Sciences, University of Turin, Italy; ²Regional Centre for Thrombotic and Hemorrhagic Diseases, AOU Città della salute e della Scienza di Torino, Italy; ³Division of Hematology, AOU Città della Salute e della Scienza, University of Turin, Italy; ⁴Central Lab Baldi and Riberi, AOU Città della salute e della Scienza di Torino, Italy

  Francesca Bocchi

  14-10-2026

  https://doi.org/10.4081/btvb.2026.646

  28

  PDF: 13

• PO117 | LONGITUDINAL THROMBIN GENERATION PROFILING IN A PATIENT WITH SEVERE HEMOPHILIA A DURING ANTITHROMBIN-LOWERING THERAPY, CANCER, AND MAJOR SURGERY C. Simion, C. Bulato, E. Campello, E. Zanon, B. Serena, S. Toffanin, P. Simioni | Department of Medicine, University of Padova, Italy

  Chiara Simion

  26-10-2026

  https://doi.org/10.4081/btvb.2026.933

  6

  PDF: 2

• PO021 | PLATELETS MATTER: THROMBIN GENERATION IN PLATELET‐RICH PLASMA VERSUS PLATELET-POOR-PLASMA UNDER NON-REPLACEMENT THERAPIES IN HAEMOPHILIA F. Bocchi^1|2, R. Pastorino^1|2, G. Murante^1|2|3, S. Bergonzi^1|2|3, M. Capetta^1|2|3, F. Valeri^2|3, C. Dainese^2|3, A. Valpreda⁴, B. Bruno^1|3, A. Borchiellini^2|3 | ¹Department of Molecular Biotechnology and Health Sciences, University of Turin, Torino, Italy; ²Regional Centre for Thrombotic and Hemorrhagic Diseases; ³Division of Hematology; ⁴Central Lab Baldi and Riberi, AOU Città della salute e della Scienza di Torino, Torino, Italy

  Francesca Bocchi

  26-10-2026

  https://doi.org/10.4081/btvb.2026.837

  7

  PDF: 1
• 

  Thrombin generation assay in COVID-19 patients shows a hypocoagulable pattern

  Giovanni L. Tiscia, Donatella Colaizzo, Antonio De Laurenzo, Filomena Cappucci, Lucia Fischetti, Elena Chinni, Mario Mastroianno, Giovanni Favuzzi, Massimo Carella, Elvira Grandone

  22-10-2024

  https://doi.org/10.4081/btvb.2024.145

  2502

  PDF: 505

  Supplementary: 263

• CO-69 | IN VITRO CORRECTION OF SEVERE FACTOR V DEFICIENCY USING A NOVEL PLASMA-DERIVED FACTOR V CONCENTRATE: A WHOLE BLOOD THROMBIN GENERATION STUDY C. Bulato¹, E. Campello¹, L. Spiezia¹, B. Serena¹, S. Toffanin¹, C. Simion¹, A. Caricasole², M. Sotgiu², A. Salvatore², F. Pierantoni², T.M. Hackeng^3|4, H.M.H. Spronk^3|4, P. Simioni¹ | ¹First Chair of Internal Medicine, Thrombotic and Haemorrhagic Diseases Unit and Haemophilia Centre, Department of Medicine, Padova University Hospital, Padova, Italy; ²Kedrion SpA, Barga Lucca, Italy; ³Coagulation Profile B.V., Maastricht, Netherland; ⁴Department of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, Netherland

  Cristiana Bulato

  14-10-2026

  https://doi.org/10.4081/btvb.2026.679

  26

  PDF: 10
• 

  The expanded universe of thrombin: a comprehensive review of its hemostasis-independent roles and structure-function relationships

  Monica Sacco, Stefano Lancellotti, Antonietta Ferretti, Maria Basso, Leonardo Di Gennaro, Raimondo De Cristofaro

  28-08-2026

  https://doi.org/10.4081/btvb.2026.462

  431

  PDF: 128

• PO69 | Whole blood thrombin generation hypercoagulable profile in a patient with hemolytic crisis due to paroxysmal nocturnal hemoglobinuria: a case report A. Napolitano, L. Spiezia, C. Bulato, E. Campello, P. Simioni | First Chair of Internal Medicine, Department of Medicine, University-Hospital of Padua Medical School, Padua, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.338

  697

  PDF: 18

• PO056 | SYNERGISTIC EFFECT OF RECOMBINANT FACTOR INFUSION ON THROMBIN GENERATION IN HEMOPHILIA PATIENTS UNDER EMICIZUMAB OR CONCIZUMAB PROPHYLAXIS F. Bocchi^1|2, R. Pastorino^1|2, M. Capetta^1|2|3, S. Bergonzi^1|2|3, G. Murante^1|2|3, F. Valeri^2|3, C. Dainese^2|3, A. Valpreda⁴, B. Bruno^1|3, A. Borchiellini^2|3 | ¹Department of Molecular Biotechnology and Health Sciences, University of Turin, Italy; ²Regional Center for Thrombotic and Hemorrhagic Diseases; ³Division of Hematology; ⁴Central Lab Baldi and Riberi, AOU Città della Salute e della Scienza di Torino, Italy

  Matilde Capetta

  26-10-2026

  https://doi.org/10.4081/btvb.2026.872

  7

  PDF: 2

• PO090 | INCOMPLETE THROMBIN INHIBITION: BIOCHEMICAL AND FUNCTIONAL EVIDENCE OF ADP P2Y1 RECEPTOR DESENSITIZATION IN HUMAN PLATELETS E. Schiera, S. De Corci, A. Di Battista, F.M. Pulcinelli | Experimental Medicine Sapienza University of Rome, Italy

  Eleonora Schiera

  26-10-2026

  https://doi.org/10.4081/btvb.2026.906

  6

  PDF: 2

• PO019 | LONGITUDINAL COAGULATION PROFILING BY THROMBIN GENERATION AND CIRCULATING MICROVESISCLES OF INDIVIDUALS UNDERGOING GENDER-AFFIRMING HORMONE THERAPY E. Campello, A. Scala, A. Napolitano, C. Simion, C. Bulato, S. Toffanin, S. Gavasso, B. Serena, A. Montagna, A. Garolla, P. Simioni | Department of Medicine, University of Padova, Italy

  Elena Campello

  26-10-2026

  https://doi.org/10.4081/btvb.2026.835

  7

  PDF: 2

• PO051 | ENDOGENOUS THROMBIN POTENTIAL RATIO AS A PREDICTOR OF BIRTHWEIGHT PERCENTILE IN PREGNANCY G. Tiscia¹, F. Cappucci¹, A. de Laurenzo¹, M.P. Palumbo¹, D. Colaizzo¹, E. Grandone^1|2 | ¹IRCCS Casa Sollievo della Sofferenza, Italy; ²Università degli Studi di Foggia, Italy

  Elvira Grandone

  26-10-2026

  https://doi.org/10.4081/btvb.2026.867

  6

  PDF: 2

• PO049 | WHOLE-BLOOD THROMBIN GENERATION ASSAY REVEALS HYPERCOAGULABLE STATE IN SICKLE CELL DISEASE IN STEADY STATE AND CORRELATES WITH CLINICAL EVENTS A. Bravin¹, E. Campello¹, A. Bertomoro¹, C. Bulato¹, B. Serena¹, S. Toffanin¹, G. Bogoni¹, F. Lucente¹, M.P. Boaro², G. Reggiani², R. Colombatti², P. Simioni¹ | ¹Department of Medicine, University of Padova, Italy; ²Pediatric Hematology-Oncology and Bone Marrow Transplant Unit, Department of Woman's and Child's Health, Padova University Hospital, Italy

  Angela Bravin

  26-10-2026

  https://doi.org/10.4081/btvb.2026.865

  6

  PDF: 1

• PO006 | FLOW-MEDIATED DILATION AND ECFC DERIVED ENDOTHELIAL DYSFUNCTION IN VENOUS THROMBOEMBOLISM C.M. Totè¹, M. Donadini^1|2, R. Ciceri^3|4, M. Bacci⁴, A. Cancellara^3|4, E. Romualdi¹, L. Guerrieri^3|4, F. Tumminello⁴, C. Lodigiani⁴, W. Ageno⁵, S. Della Bella^3|4, F. Calcaterra^3|4, D. Mavilio^3|4 | ¹ASST Sette Laghi, Varese, Italy; ²Università of Insubria, Varese, Italy; ³University of Milano, Milano, Italy; ⁴IRCCS Humanitas Research Hospital, Rozzano, Italy; ⁵Università of Padua, Padova, Italy

  Chiara Maria TotÈ

  26-10-2026

  https://doi.org/10.4081/btvb.2026.822

  8

  PDF: 1

• PO055 | THROMBIN GENERATION PROFILES IN PATIENTS WITH WILD-TYPE TRANSTHYRETIN AMYLOIDOSIS L. Spiezia¹, A. Napolitano¹, C. Bulato¹, S. Toffanin¹, A. Benetti¹, C. Samà¹, L. De Michieli², G. Sinigiani², A. Cipriani², P. Simioni¹ | ¹Dipartimento di Medicina, Azienda Osp. Università di Padova, Italy; ²Dipartimento di Scienze cardio toraco vascolari, Azienda Osp. Università di Padova, Italy

  Luca Spiezia

  26-10-2026

  https://doi.org/10.4081/btvb.2026.871

  6

  PDF: 2

• CO073 | THROMBIN GENERATION PROFILE IN ELDERLY PATIENTS WITH ATRIAL FIBRILLATION: IMPACT OF ORAL ANTICOAGULANT TYPE M. Di Gioia¹, M. Berteotti^1|2, G. Ciarrocca Taranta², F. Alfano^1|2, F. Crudele¹, F. Cesari¹, A.M. Gori^1|2, A. Rogolino¹, B. Giusti^1|2, R. Marcucci^1|2 | ¹Atherothrombotic Diseases, Careggi University Hospital, Firenze, Italy; ²Dep. of Experimental and Clinical Medicine, University of Florence, Italy

  Michela Di Gioia

  26-10-2026

  https://doi.org/10.4081/btvb.2026.775

  6

  PDF: 2

• CO15 | Longitudinal coagulation profiling of individuals undergoing gender-affirming hormone therapy: the hyper-gender study A. Napolitano, E. Campello, A. Scala, C. Simion, C. Bulato, S. Gavasso, C. Samà, A. Benetti, S. Toffanin, G. Faggian, R. Scafa, A. Garolla, P. Simioni | First Chair of Internal Medicine, Department of Medicine, University Hospital of Padua; Unit of Andrology and Reproductive Medicine, Department of Medicine, University Hospital of Padua, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.219

  668

  PDF: 18
• 

  Platelets versus monocytes as cellular sources of blood-borne tissue factor: a quantitative and functional comparison in healthy subjects and in patients with STEMI

  Marina Camera, Marta Brambilla, Alessia Becchetti, Patrizia Della Valle, Nicola Cosentino, Jeness Campodonico, Gian Carlo Marenzi, Daniela Trabattoni, Peter L.A. Giesen, Vincenzo Toschi, Elena Tremoli

  12-10-2026

  https://doi.org/10.4081/btvb.2026.584

  344

  PDF: 45

  SUPPLEMENTARY FILES: 24

• CO101 | PLATELET ACTIVATION AND THROMBOGENICITY IN ANTI-PHOSPHOLIPID ANTIBODY-POSITIVE SUBJECTS: AN INTEGRATED TGA AND T-TAS ANALYSIS G. Rosati¹, A. Pozzi¹, C. Barale¹, M. Padrini¹, R.M. Medici¹, G. Ferrari¹, E. Mordohovich¹, M. Tamietti¹, A. Barinotti², M. Radin², M. Geminiani¹, M. De Gobbi¹, I. Russo¹, A. Morotti¹ | ¹Dip. Scienze Cliniche e Biologiche, Torino, Italy; ²Osp. San Giovanni Bosco, Torino, Italy

  Giorgio Rosati

  26-10-2026

  https://doi.org/10.4081/btvb.2026.803

  5

  PDF: 2

• PO073 | ANALYTICAL VARIABILITY IN FIBRINOGEN TESTING REVEALING FIBRINOGEN LONGMONT: A CASE REPORT A. Paradiso¹, S. Cmet², E. Fontanini² | ¹Dep. of Medicine, University of Udine, Udine, Italy; ²Dep. of Laboratory Medicine, Institute of Clinical Pathology, Azienda Ospedaliera Universitaria Friuli Centrale, Udine, Italy

  Antonella Paradiso

  26-10-2026

  https://doi.org/10.4081/btvb.2026.889

  7

  PDF: 2

• PO122 | SUCCESSFUL MANAGEMENT OF THERAPEUTIC ANTICOAGULATION FOR PROVOKED VENOUS THROMBOEMBOLISM IN A PATIENT WITH FACTOR VII DEFICIENCY AND SEPTIC SHOCK S. Birocchi¹, F.M. Monda¹, B. Clerici^1|2, M. Scavone², R. Cabiddu¹, E. Pontisso¹, C. Ortelli¹, M.L.G. Perego¹, E. Fiorini¹, L. Catarini¹, A. Bortoli¹, M. Manzoni¹, F.M. Casanova¹, A. Tripodi^2|3, F. Peyvandi^2|3, G.M. Podda^1|2 | ¹S.C. Medicina Generale 2, Ospedale San Paolo, ASST Santi Paolo e Carlo, Milano, Italy; ²Dipartimento di Scienze della Salute, Università degli Studi di Milano, Italy; ³Centro di riferimento emofilia e trombosi "Emilio Bianchi"; ⁴S. Birocchi and F.M. Monda contributed equally as co-first authors

  Simone Birocchi

  26-10-2026

  https://doi.org/10.4081/btvb.2026.938

  7

  PDF: 2

• PO040 | PHARMACODYNAMIC CHARACTERIZATION OF THROMBIN GENERATION IN SEVERE HEMOPHILIA A PATIENTS ON EMICIZUMAB PROPHYLAXIS: A REAL-WORLD LONGITUDINAL STUDY M. Bergamaschi, A. Pallotta, M. Biglietto, S. Sorella, S. Ligia, E. Baldacci, A. Chistolini, C. Santoro, R. Mormile | Department of translational and precision Medicine, Sapienza, University of Rome, Italy

  Martina Bergamaschi

  26-10-2026

  https://doi.org/10.4081/btvb.2026.856

  6

  PDF: 2

• CO-28 | SYNERGISTIC EFFECT OF RECOMBINANT FACTOR INFUSION ON THROMBIN GENERATION IN HEMOPHILIA PATIENTS UNDER EMICIZUMAB OR CONCIZUMAB PROPHYLAXIS F. Bocchi^1|2, R. Pastorino^1|2, G. Murante^1|2|3, S. Bergonzi^1|2|3, M. Capetta^1|2|3, F. Valeri^2|3, C. Dainese^2|3, A. Valpreda⁴, B. Bruno^1|3, A. Borchiellini^2|3 | ¹Department of Molecular Biotechnology and Health Sciences, University of Turin, Italy; ²Regional Centre for Thrombotic and Hemorrhagic Diseases, AOU Città della salute e della Scienza di Torino, Italy; ³Division of Hematology, AOU Città della Salute e della Scienza, University of Turin, Italy; ⁴Central Lab Baldi and Riberi, AOU Città della salute e della Scienza di Torino, Italy

  Francesca Bocchi

  14-10-2026

  https://doi.org/10.4081/btvb.2026.638

  30

  PDF: 19

• CO086 | CLINICAL AND GENETIC CHARACTERIZATION OF A NEW FAMILY CARRYING THE “FACTOR VIII PADUA” F8 DUPLICATION E. Campello, C. Simion, F. Sartorello, D. Regazzo, C. Bulato, B. Serena, S. Toffanin, L. Spiezia, P. Simioni | Department of Medicine, University of Padova, Italy

  Elena Campello

  26-10-2026

  https://doi.org/10.4081/btvb.2026.788

  9

  PDF: 2

• PO47 | Hemophilia A and antithrombin deficiency: a case of natural hemostatic rebalancing L. Torrieri, S. Ligia, E. Baldacci, R. Mormile, S. Sorella, R. Ciciani, M. Biglietto, N. Zhdanovskaya, A. Delli Paoli, A. Tirnetta, M. Lorenzon, C. Santoro | Hematology, Department of Translational and Precision Medicine, Policlinico Umberto I, Sapienza University of Roma, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.316

  627

  PDF: 12

• PO053 | PLATELET AGGREGATION AND THROMBIN GENERATION IN MULTIPLE MYELOMA: A PROSPECTIVE STUDY M. Biglietto, M. Mormile, A. Piciocchi, F. Fazio, M. Capriata, S. Sorella, E. Baldacci, A. Chistolini, M.T. Petrucci, C. Santoro | Sapienza University of Roma, Italy

  Mario Biglietto

  26-10-2026

  https://doi.org/10.4081/btvb.2026.869

  6

  PDF: 1
• 

  Comparison among three different bleeding scores and the thrombin generation assay to assess the different hemorrhagic phenotypes in patients with FVII deficiency

  Samantha Pasca, Cristina Santoro, Chiara Ambaglio, Marisanta Napolitano, Marta Milan, Letizia Natali, Silvia Nannizzi, Filippo Mori, Paolo Simioni, Ezio Zanon

  23-05-2022

  https://doi.org/10.4081/btvb.2022.12

  5642

  PDF: 534

• PO052 | VALIDATION OF THROMBIN GENERATION MEASUREMENT IN PLATELET- RICH-PLASMA: EVOLUTION IN THE ST GENESIA^® SYSTEM F. Bocchi^1|2, R. Pastorino^1|2, G. Murante^1|2|3, S. Bergonzi^1|2|3, M. Capetta^1|2|3, F. Valeri^2|3, C. Dainese^2|3, A. Valpreda⁴, B. Bruno^1|3, A. Borchiellini^2|3 | ¹Department of Molecular Biotechnology and Health Sciences, University of Turin, Torino, Italy; ²Regional Centre for Thrombotic and Hemorrhagic Diseases, AOU Città della salute e della Scienza di Torino, Torino, Italy; ³Division of Hematology, AOU Città della Salute e della Scienza, Università di Torino, Torino, Italy; ⁴Central Lab Baldi and Riberi, AOU Città della salute e della Scienza di Torino, Torino, Italy

  Francesca Bocchi

  26-10-2026

  https://doi.org/10.4081/btvb.2026.868

  8

  PDF: 2

• CO-43 | VALIDATION OF THROMBIN GENERATION MEASUREMENT IN PLATELET-RICH PLASMA: EVOLUTION IN THE ST GENESIA^® SYSTEM F. Bocchi^1|2, R. Pastorino^1|2, G. Murante^1|2|3, S. Bergonzi^1|2|3, M. Capetta^1|2|3, F. Valeri^2|3, C. Dainese^2|3, A. Valpreda⁴, B. Bruno^1|3, A. Borchiellini^2|3 | ¹Department of Molecular Biotechnology and Health Sciences, University of Turin, Italy; ²Regional Centre for Thrombotic and Hemorrhagic Diseases, AOU Città della salute e della Scienza di Torino, Italy; ³Division of Hematology, AOU Città della Salute e della Scienza, University of Turin, Italy; ⁴Central Lab Baldi and Riberi, AOU Città della salute e della Scienza di Torino, Italy

  Francesca Bocchi

  14-10-2026

  https://doi.org/10.4081/btvb.2026.653

  19

  PDF: 12

• CO110 | FLOW-BASED WHOLE-BLOOD THROMBUS PROFILING DISCRIMINATES ANTITHROMBOTIC DRUG EFFECTS AND UNCOVERS PLATELET-DEPENDENT COAGULATION DEFECTS AFTER CARDIOPULMONARY BYPASS A. Foladore¹, S. Lattanzio¹, E. Baryshnikova², M. Anguissola², E. Lombardi³, M. Valvasori³, R. Vettori³, F. Agostini³, R. Tassan Toffola⁴, L. Rota¹, M. Ranucci², M. Mazzucato³ | ¹Sedicidodici s.r.l., Pordenone, Italy; ²IRCCS Policlinico San Donato, San Donato Milanese, Italy; ³Centro di Riferimento Oncologico (CRO) IRCCS, Aviano, Italy; ⁴Azienda Sanitaria Friuli Occidentale, Pordenone, Italy

  Mario Mazzucato

  26-10-2026

  https://doi.org/10.4081/btvb.2026.812

  2

  PDF: 2
• 

  PO04 | FIBRIN CLOT SHIELDS PROMOTE CLONAL SELECTION IN CANCER CELLS: PROCOAGULANT ACTIVITY AND SURVIVAL OF CLOT-EMBEDDED CELLS. A NOVEL TUMOR MICROENVIRONMENT MODEL M.A. Baghdadi^1|2, E. Mbemba¹, P. Las Casa¹, P. Van Dreden^1|3, N. Saleem^1|4, J. Fareed⁴, P. Kempaiah⁴, M. Sabbah¹, G. Gerotziafas^1|4 | ¹Sorbonne University, INSERM UMR_S_938, CRSA, Research Department "Cancer, Vessels, Biology and Therapeutics" (CaVITE), Research Group "Cancer-Angiogenesis-Thrombosis and Haemostasis," Thrombosis Center, University Institute of Cancerology, Saint Antoine University Hospital Assistance Publique Hôpitaux de Paris (AP-HP) Paris, France; ²Research Center, King Faisal Specialist Hospital and Research Center, Jeddah, Saudi Arabia; ³Diagnostica Stago, Gennevilliers, France; ⁴Center of Translational Research and Education, Department of Pathology and Laboratory Medicine, Loyola University Stritch School of Medicine, Maywood, Ill., USA

  ICTHIC 2026

  16-04-2026

  https://doi.org/10.4081/btvb.2026.500

  467

  PDF: 94
• 

  Influence of emicizumab on protein C-mediated clotting regulation

  Federica Mancazzo, Antonia Vitulli, Lavinia Dirienzo, Concetta T. Ammollo, Fabrizio Semeraro, Mario Colucci

  25-10-2023

  https://doi.org/10.4081/btvb.2023.89

  2649

  PDF: 440

  Supplementary Material: 137
• 

  PO02 | SYNERGISTIC INTERACTION OF ENDOTHELIAL AND CANCER CELLS IN THE FORMATION AND STRUCTURE OF THE FIBRIN CLOT SHIELDS M.A. Baghdadi^1|2, E. Mbemba¹, P. Las Casa¹, P. Van Dreden^1|3, N. Saleem^1|4, J. Fareed⁴, P. Kempaiah⁴, M. Sabbah¹, G. Gerotziafas^1|4 | ¹Sorbonne University, INSERM UMR_S_938, CRSA, Research Department "Cancer, Vessels, Biology and Therapeutics" (CaVITE), Research Group "Cancer-Angiogenesis-Thrombosis and Haemostasis," Thrombosis Center, University Institute of Cancerology (UIC), Saint Antoine University Hospital Assistance Publique Hôpitaux de Paris (AP-HP) Paris France; ²Research Center, King Faisal Specialist Hospital and Research Center, Jeddah, Saudi Arabia; ³Diagnostica Stago, clinical research, Gennevilliers, France; ⁴Center of Translational Research and Education, Department of Pathology and Laboratory Medicine, Loyola University Stritch School of Medicine, Maywood, Ill., USA

  ICTHIC 2026

  16-04-2026

  https://doi.org/10.4081/btvb.2026.498

  454

  PDF: 99

• PO58 | Gender differences in primary haemostasis A. Becchetti², M. Brambilla², M. Conti², D. Trabattoni², E. Tremoli³, M. Camera^1,2 | ¹Department of Pharmaceutical Sciences, Università degli Studi di Milano; ²Centro Cardiologico Monzino IRCCS, Milan; ³Maria Cecilia Hospital, Cotignola (RA), Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.327

  641

  PDF: 12

• CO087 | PLATELET ACTIVATION AND THROMBOSIS IN PATIENTS WITH FACTOR V LEIDEN MUTATION: A CROSS-SECTIONAL STUDY V. Cammisotto¹, E. Valeriani², S. Bartimoccia¹, V. Castellani¹, A. Pannunzio³, I. Palumbo³, C. Nocella¹, R. Carnevale⁴, F. Violi¹, P. Pignatelli¹ | ¹Department of Medical and Cardiovascular Sciences, Sapienza University of Roma, Italy; ²Department of Infectious Disease, AOU Policlinico Umberto I, Roma, Italy; ³Department of General Surgery and Surgical Speciality, Sapienza University of Roma, Italy; ⁴Department of Medical-Surgical Sciences and Biotechnologies, Sapienza University of Roma, Italy

  Mariangela Scavone

  26-10-2026

  https://doi.org/10.4081/btvb.2026.789

  8

  PDF: 2
• 

  Cancer-associated thrombosis: limitations of conventional models and advances with endothelial cell-based microfluidics incorporating thrombin generation

  Dongyue Fan, Araci M.R. Rondon, Henri H. Versteeg

  16-04-2026

  https://doi.org/10.4081/btvb.2026.438

  812

  PDF: 145

• CO058 | ELEVATED PLASMA LEVELS OF OMEGA-3 STEARIDONIC ACID ARE ASSOCIATED WITH DECREASED FACTOR VIII COAGULANT ACTIVITY INDEPENDENTLY OF FACTOR VIII ANTIGEN AND VON WILLEBRAND FACTOR LEVELS: PRELIMINARY RESULTS FROM AN ANGIOGRAPHICALLY-CONTROLLED CARDIOVASCULAR COHORT STUDY N. Osti¹, G. Musuraca¹, A. Castagna², M. Spizzo², P. Pattini², G. Mango², M. Baroni³, B. Lunghi³, G. Poli⁴, C. Brocco¹, C. Angheben¹, M. Grusse⁵, P. Van Dreden⁵, A. Anesi¹, G. Lippi³, M. Del Greco¹, S. Friso², A. Ferro¹, F. Bernardi³, N. Martinelli² | ¹Azienda Sanitaria Universitaria Integrata del Trentino, Trento, Italy; ²Dip. di Medicina, Università di Verona, Verona, Italy; ³Dip. di Scienze della Vita e Biotecnologie, Università di Ferrara, Ferrara, Italy; ⁴Sez. di Biochimica Clinica, Università di Verona, Verona, Italy; ⁵Clinical Research, Diagnostica STAGO, Gennevillers, France

  Nicola Osti

  26-10-2026

  https://doi.org/10.4081/btvb.2026.760

  6

  PDF: 2
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  The clinical usefulness of measuring thrombin generation

  Coenraad H. Hemker

  06-03-2023

  https://doi.org/10.4081/btvb.2023.62

  1421

  PDF: 603

• CO34 | Evaluation of emicizumab concentration and thrombin generation in a cohort of severe hemophilia A patients with and without inhibitor A. Taglietti¹, S. Ligia¹, F. Paoletti¹, R. Mormile¹, E. Baldacci², A. Chistolini¹, C. Santoro^1,2 | ¹Hematology, Department of Translational and Precision Medicine, Sapienza University of Roma; ²Hematology, Azienda Ospedaliera Universitaria Policlinico Umberto I, Roma, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.241

  670

  PDF: 12

• CO111 | ROLE OF CONSTITUTIVE ENDOTHELIAL DYSFUNCTION IN THE PATHOGENESIS OF UNPROVOKED VENOUS THROMBOEMBOLISM: CHARACTERIZATION OF ENDOTHELIAL COLONY-FORMING CELLS AND ASSOCIATION WITH RISK OF RECURRENCE F. Calcaterra^1|2, R. Ciceri^1|2, M. Bacci¹, A. Cancellara^1|2, E. Romualdi³, L. Guerrieri^1|2, F. Tumminello¹, C. Lodigiani¹, W. Ageno⁴, S. Della Bella^1|2, D. Mavilio^1|2, M.P. Donadini^3|5 | ¹IRCCS Humanitas Research Hospital, Italy; ²University of Milano, Italy; ³ASST Sette Laghi, Varese, Italy; ⁴University of Padua, Padova, Italy; ⁵University of Insubria, Varese, Italy

  Marco Paolo Donadini

  26-10-2026

  https://doi.org/10.4081/btvb.2026.813

  8

  PDF: 2
• 

  The key to fibrinolysis and thrombolysis

  Roger Lijnen, Désiré Collen

  09-09-2025

  https://doi.org/10.4081/btvb.2025.368

  1692

  PDF: 523

  HTML: 261

• PO25 | Baseline thrombin generation test does not predict thrombotic events in acute leukemia: a monocentric prospective study M. Biglietto, R. Mormile, M.L. Bisegna, A. Laganà, A. L. Faccini, A. Papa, E. Baldacci, C. Santoro, M.S. De Propris, A. Chistolini | Hematology, Department of Translational and Precision Medicine Sapienza University of Roma, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.286

  647

  PDF: 12

• CO070 | PLASMIN GENERATION AND ITS INTERPLAY WITH COAGULATION AND FIBRINOLYSIS IN ATRIAL FIBRILLATION: IMPACT OF ANTICOAGULANT THERAPY G. Ciarrocca Taranta¹, F. Alfano¹, M. Di Gioia², M. Berteotti^1|2, E. Lotti², F. Cesari², A. Rogolino², F.A. Barbuto¹, A. M Gori^1|2, E. Sticchi^1|2, B. Giusti^1|2, R. Marcucci^1|2 | ¹Dep of Experimental and Clinical Medicine, University of Florence, Italy; ²Atherothrombotic Diseases, Careggi University Hospital, Firenze, Italy

  Giulia Ciarrocca Taranta

  26-10-2026

  https://doi.org/10.4081/btvb.2026.772

  9

  PDF: 2
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  PO42 | DIFFERENTIAL EXPRESSION OF HEMOSTATIC BIOMARKERS ACROSS CANCER TYPE AND DISEASE STAGE: A PROSPECTIVE ANALYSIS OF 4,292 PATIENTS FROM THE HYPERCAN STUDY P. Gómez-Rosas^1|2|, D. Romeo¹, S. Bolognini¹, C. Ticozzi¹, F. Schieppati¹, A. D’Alessio⁴, R. Labianca⁴, A. Falanga^1|5|6, M. Marchetti^1|5|6 | ¹Hospital Papa Giovanni XXIII, Bergamo, Italy; ²Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, the Netherlands; ³Hospital de Oncologia, Unidad Medica de Alta Especialidad (UMAE), Centro Medico Nacional Siglo XXI, Instituto Mexicano del Seguro Social (IMSS), Mexico City, Mexico; ⁴Fondazione ARTET Onlus, Bergamo, Italy; ⁵ERN EuroBloodNet; ⁶School of Medicine and Surgery, University of Milan Bicocca, Italy; *On Behalf Of The Hypercan Investigators

  ICTHIC 2026

  16-04-2026

  https://doi.org/10.4081/btvb.2026.536

  496

  PDF: 110

• PO52 | Comprehensive assessment of variables affecting spontaneous platelet aggregation C. Ghali¹, A. Fioretti¹, M. Scavone¹, E. Bossi¹, B. Clerici¹, S. Birocchi¹, E. Popov², M. Centola³, G.M. Podda¹, M. Cattaneo⁴ | ¹Divisione di Medicina Generale II, ASST Santi Paolo e Carlo, DISS, Università degli Studi di Milano, Italy; ²National Medical Research Center of Cardiology, Ministry of Health of the Russian Federation, Moscow; ³Division of Cardiology, Pio XI Hospital, ASST Brianza, Desio, Italy; ⁴Fondazione Arianna Anticoagulazione, Bologna, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.321

  674

  PDF: 20

• CO037 | PERFORMANCE OF A QUALITATIVE POINT-OF-CARE TEST IN PATIENTS EXPERIENCING ACUTE THROMBOEMBOLIC OR MAJOR BLEEDING EVENTS TREATED WITH DOACs: THE T-BLEEDOAC MULTICENTER PROSPECTIVE COHORT STUDY M. Vedovati¹, G. Pepe², S. Vanni³, E. Campello⁴, F. Morello⁵, S. Beccatini¹, D. Giudici¹, F. Lucarini², L. Parmeggiani³, G. Fabiani³, P. Simioni⁴, M. Santoro⁵, P. Nazerian⁶, M. Mosconi¹, C. Becattini¹ | ¹University of Perugia, Perugia, Italy; ²Versilia Hospital, Tuscany North West Health System, Lido di Camaiore (LU), Italy; ³Università di Firenze, Firenze, Italy; ⁴University of Padua, Padova, Italy; ⁵A.O.U. Città della Salute e della Scienza, Torino, Italy; ⁶Careggi University Hospital, Firenze, Italy

  Maria Cristina Vedovati

  26-10-2026

  https://doi.org/10.4081/btvb.2026.739

  6

  PDF: 1
• 

  Anticoagulation in obese patients: challenges and strategies

  Alice Lipari, Esmeralda Capristo, Antonietta Ferretti, Erica De Candia

  18-09-2025

  https://doi.org/10.4081/btvb.2025.174

  2029

  PDF: 530

  HTML: 303

  XML: 186

• CO072 | PERSISTENT ENDOTHELIAL THROMBOINFLAMMATORY PHENOTYPE IN PATENT FORAMEN OVALE: EVIDENCE FROM PATIENT-DERIVED ENDOTHELIAL COLONY-FORMING CELLS M. Conti¹, D. Trabattoni¹, F. Vieceli Dalla Sega², F. Fortini², A. Becchetti¹, P. Della Valle¹, M. Brambilla¹, M. Chiesa¹, C. Pericleous³, A. Randi³, E. Tremoli², M. Camera^1|4 | ¹Centro Cardiologico Monzino IRCCS, Milano, Italy; ²Maria Cecilia Hospital, GVM Care & Research, Cotignola, Italy; ³Imperial College London, London, United Kingdom; ⁴Università degli Studi di Milano, Department of Pharmaceutical Sciences, Milano, Italy

  Maria Conti

  26-10-2026

  https://doi.org/10.4081/btvb.2026.774

  8

  PDF: 1

• PO076 | ACQUIRED FACTOR V INHIBITOR WITH CONCOMITANT LUPUS ANTICOAGULANT: DIAGNOSTIC PITFALLS AND THERAPEUTIC CHALLENGES G. Gazzelli¹, Y. Azzanelli¹, C. Vernarecci¹, F. Marotta¹, F. Giacopelli¹, E. Cenni², V. Agostini², L. Banov¹, AC Molinari¹ | ¹IRCCS Istituto Giannina Gaslini, Italy; ²IRCSS AOM S. Martino Genova, Italy

  Angelo Claudio Molinari

  26-10-2026

  https://doi.org/10.4081/btvb.2026.892

  8

  PDF: 2

• CO010 | MAPPING HEMOSTATIC BIOMARKER EXPRESSION ACROSS CANCER TYPES AND STAGES WITHIN THE HYPERCAN COHORT P. Gómez-Rosas^1|2, D. Romeo¹, S. Bolognini¹, C. Ticozzi¹, F. Schieppati^1|4|5, A. D’Alessio³, R. Labianca³, L. Barcella^1|4|5, A. Falanga^3|5, M. Marchetti^1|4|5 | ¹Hospital Papa Giovanni XXIII, Bergamo, Italy; ²Hospital de Oncología, Unidad Médica de Alta Especialidad (UMAE), Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social (IMSS), Ciudad de México, México; ³Fondazione ARTET Onlus, Bergamo, Italy; ⁴ERN EuroBloodNet; ⁵School of Medicine and Surgery, University of Milan Bicocca, Italy. On behalf of the HYPERCAN Investigators

  Marina Marchetti

  26-10-2026

  https://doi.org/10.4081/btvb.2026.712

  7

  PDF: 2
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  PO44 | PREDICTORS OF ONE-YEAR MORTALITY IN NEWLY DIAGNOSED METASTATIC BREAST CANCER: THE PROGNOSTIC ROLE OF HEMOSTATIC BIOMARKERS AND EARLY THROMBOEMBOLISM M. Marchetti^1|2|3, P. Gomez-Rosas^1|4|5, S. Bolognini¹, C. Ticozzi¹, D. Romeo¹, F. Schieppati^1|3, L. Barcella^1|3, F. Petrelli⁶, A. D'Alessio⁷, R. Labianca⁷, A. Falanga^1|2|3 | ¹Immunohematology and Transfusion Medicine, Hospital Papa Giovanni XXIII, Bergamo, Italy; ²School of Medicine and Surgery, University of Milan Bicocca, Milan, Italy; ³ERN EuroBloodNet; ⁴Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, The Netherlands; ⁵Hospital de Oncologia, Unidad Medica de Alta Especialidad (UMAE), Centro Medico Nacional Siglo XXI, Instituto Mexicano del Seguro Social (IMSS), Mexico City, Mexico; ⁶Oncology Unit, Hospital Treviglio-Caravaggio, Treviglio, Italy; ⁷Fondazione ARTET Onlus, Bergamo, Italy; *On behalf of the Hypercan Investigators

  ICTHIC 2026

  16-04-2026

  https://doi.org/10.4081/btvb.2026.538

  460

  PDF: 106

• PO139 | PFO-LIKE INTRACARDIAC FLOW IS SUFFICIENT TO INDUCE A PROTHROMBOTIC PLATELET PHENOTYPE: EVIDENCE FROM A MICROFLUIDIC MODEL OF PATENT FORAMEN OVALE M. Conti¹, V. Guadagno², D. Trabattoni¹, A. Becchetti¹, F. Morelli², L. Fusini¹, M. Brambilla¹, S. Bozzi², A. Redaelli², M. Camera^1|3 | ¹Centro Cardiologico Monzino IRCCS, Milano, Italy; ²Politecnico di Milano, Department of Electronics, Informatics and Bioengineering (DEIB), Milano, Italy; ³Università degli Studi di Milano, Department of Pharmaceutical Sciences, Milano, Italy

  Maria Conti

  26-10-2026

  https://doi.org/10.4081/btvb.2026.955

  7

  PDF: 3

• CO-83 | ACQUIRED FACTOR V DEFICIENCY IN A HIGH-THROMBOTIC-RISK PATIENT: DIAGNOSTIC DILEMMA AND SUCCESSFUL MANAGEMENT G. Gazzelli¹, L. Banov¹, Y. Azzanelli¹, C. Vernarecci¹, F. Marotta¹, F. Giacopelli¹, E. Cenni², V. Agostini², A.C. Molinari¹ | ¹IRCCS Istituto Giannina Gaslini, Italy; ²IRCSS AOM S. Martino, Genova, Italy

  Angelo Claudio Molinari

  14-10-2026

  https://doi.org/10.4081/btvb.2026.693

  36

  PDF: 20

• PO09 | Comparison of different aggregometry methods for evaluation of platelet function in patients with myeloproliferative neoplasms C. Fortino, I. Bertozzi, D. Regazzo, L. Gianesello, G. Nuozzi, F. Sartorello, V. Azzaro, G. Saggiorato, A. Bertomoro, P. Simioni | First Medical Clinic, Department of Medicine – DIMED, Università degli Studi di Padova, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.271

  552

  PDF: 12

• PO017 | BEYOND IONIC STRENGTH: ANION EFFECTS ON FIBRIN CLOT FORMATION, STRUCTURE, AND MECHANICAL PROPERTIES C. Spoliti¹, T. Feller², F.L. Macrae², R.A.S. Ariëns², R. De Cristofaro^1|3, E. Di Stasio^4|5 | ¹Department of Translational Medicine and Surgery, Università Cattolica del Sacro Cuore, Roma, Italy; ²Discovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, United Kingdom; ³Hemorrhagic and Thrombotic Diseases Center, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy; ⁴Department of Basic Biotechnological Sciences, Intensive Care and Perioperative Clinics, Università Cattolica del Sacro Cuore, Roma, Italy; ⁵Clinical Chemistry, Biochemistry and Molecular Biology Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy

  Claudia Spoliti

  26-10-2026

  https://doi.org/10.4081/btvb.2026.833

  7

  PDF: 2

• CO066 | COAGULOPATHY IN CAR-T CELL-TREATED PATIENTS WITH LYMPHOPROLIFERATIVE DISORDERS: A RETROSPECTIVE, SINGLE-CENTER OBSERVATIONAL STUDY I. Santo¹, R. Morganti², G. Leoni³, G. Tancredi³, L. Contino⁴, S. Galimberti³, R.M. Santi⁴, E. Orciuolo⁵ | ¹Azienda Toscana Nord Ovest, Versilia Hospital, Italy; ²Hematology Division AOUP, Pisa, Italy; ³University of Pisa, Hematology Pisa, Italy; ⁴Azienda Ospedaliera Universitaria Alessandria, Italy; ⁵Azienda Ospedaliera Universitaria Pisana, Hematology Pisa, Italy

  Ignazio Santo

  26-10-2026

  https://doi.org/10.4081/btvb.2026.768

  8

  PDF: 2
• 

  Is non-alcoholic fatty liver disease a prothrombotic risk factor?

  Niccolò Bitto, Vincenzo La Mura, Anna Ludovica Fracanzani, Armando Tripodi

  19-05-2023

  https://doi.org/10.4081/btvb.2023.81

  1134

  PDF: 544

• CO-73 | WHEN BLEEDING MIMICS THROMBOSIS: DIAGNOSTIC DELAY AND THROMBOTIC COMPLICATIONS IN ACQUIRED HEMOPHILIA A R. Tomasello¹, M. Mattana¹, S. Raso¹, F. Schirò¹, P. Polidori², M.I. Di Lena³, F. La Gattuta⁴, M. Napolitano¹ | ¹Ematologia e malattie rare, PO Cervello di Palermo, Italy; ²Farmacia ospedaliera, PO Cervello di Palermo, Italy; ³Direzione medica, PO Cervello di Palermo, Italy; ⁴Radiologia interventistica, PO Villa Sofia di Palermo, Italy

  Riccardo Tomasello

  14-10-2026

  https://doi.org/10.4081/btvb.2026.683

  31

  PDF: 10

• CO46 | Comparison of reticulated platelet procoagulant role in liver cirrhosis vs. fibrosis S. Toffanin¹, E. Campello¹, A. Zanetto², G. Gagliardi¹, A. Napolitano¹, E. Stocco¹, G. Gobbo¹, E. Pinto², C. M. Radu¹, M. Senzolo², L. Fabris¹, P. Simioni¹ | ¹First Chair of Internal Medicine, Department of Medicine, University-Hospital of Padua Medical School, Padova; ²Department of Surgery Oncology and Gastroenterology, Gastroenterology and Multivisceral Transplant Unit, Padova University Hospital, Padova, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.256

  590

  PDF: 18
• 

  PO19 | THE INTER-RELATIONSHIP BETWEEN NETOSIS, THE ADAMTS-13/VWF AXIS, AND HEMOSTATIC ACTIVATION IN PATIENTS WITH GYNECOLOGICAL MALIGNANCIES: PROGNOSTIC SIGNIFICANCE AND IMPACT OF CHEMOTHERAPY A. Makatsariya¹, E. Beloborodova²,V. Bitsadze¹, J. Khizroeva¹, A. Vorobev¹, A. Solopova¹, M. Tretyakova¹, N. Gashimova¹, K. Grigoreva¹, A. Oskolkova¹, J. Christophe Gris^1|3, I. Elalamy^1|4|5, G. Gerotziafas^1|4|5 | ¹Department of Obstetrics, Gynecology and Perinatal Medicine, N. F. Filatov Clinical Institute of Children’s Health, I. M. Sechenov First Moscow State Medical University Sechenov University, Moscow, Russia; ²MEDSI Network of Medical Centers, Moscow, Russia; ³Faculty of Pharmaceutical and Biological Sciences, Montpellier University, France; ⁴Department Hematology and Thrombosis Center, Medicine Sorbonne University, Paris, France; ⁵Hospital Tenon, Paris, France

  ICTHIC 2026

  16-04-2026

  https://doi.org/10.4081/btvb.2026.514

  464

  PDF: 94

• PO57 | Direct oral anticoagulant determination in urine samples compared to plasma concentrations in outpatients with atrial fibrillation and obesity A. Pannunzio¹, I.M. Palumbo¹, D. Menichelli¹, V. Cammisotto², V. Castellani³, E. Baldacci⁴, R. Mormile⁴, A. Chistolini⁴, G. Bernardini⁵, N. Porcu¹, D. Pastori², J. Harenberg⁶, F. Violi², P. Pignatelli² | ¹Department of General Surgery, Surgical Specialties and Organ Transplantation Paride Stefanini, Sapienza University of Roma, Italy; ²Department of Clinical Internal, Anesthesiological and Cardiovascular Sciences, Sapienza University of Roma, Italy; ³Department of Translational and Precision Medicine, Sapienza University of Roma, Italy; ⁴Department of Hematology, Oncology and Dermatology, Sapienza University of Roma, Italy; ⁵U.O.S.D. Medicina Rigenerativa DAI, Medicina Diagnostica e Radiologia, Policlinico Umberto 1, Roma, Italy; ⁶Ruprecht Karls University of Heidelberg, Germany

  22-10-2025

  https://doi.org/10.4081/btvb.2025.326

  545

  PDF: 16
• 

  Bioequivalence of von Willebrand factor-containing concentrates: implications for the choice in patients with von Willebrand disease. A position paper from the Italian Association of Hemophilia Centers

  Ezio Zanon, Giancarlo Castaman, Augusto Bramante Federici, Maria Elisa Mancuso, Gianfranco Pasut, Alberto Tosetto, Angiola Rocino, Rita Carlotta Santoro

  26-01-2026

  https://doi.org/10.4081/btvb.2026.415

  1290

  PDF: 344

  HTML: 163
• 

  PO07 | PLATELET INHIBITION BY THE NOVEL NITRIC OXIDE-DONOR NITROSOOXYPROPANOL M. Lindkvist, J. Jakobsson, F. Lynfeldt, B. Sandberg, K. Fransén, K. Nilsson, M. Grenegård | Cardiovascular Research Centre, Faculty of Medicine and Health, Örebro University, Örebro, Sweden

  ICTHIC 2026

  16-04-2026

  https://doi.org/10.4081/btvb.2026.503

  435

  PDF: 106

• PO095 | HEPARIN-INDUCED THROMBOCYTOPENIA PRESENTING AS A CIRCUIT-TRIGGERED PULMONARY SYNDROME IN HEMODIALYSIS: A CASE REPORT S.P. Colapietra, M. Gino | Osp. Molinette, Torino, Italy

  Selene Pia Colapietra

  26-10-2026

  https://doi.org/10.4081/btvb.2026.911

  6

  PDF: 3

• CO050 | INTERACTION BETWEEN DIRECT ORAL ANTICOAGULANTS AND ANTIEPILEPTIC DRUGS: A MULTICENTER OBSERVATIONAL STUDY A. Lipari¹, S. Sorrentino¹, M. De Siati¹, L. D'Innocenzo¹, A. Ferretti¹, D. Menichelli², V. Cammisotto², P. Pignatelli², G. Ragna³, MC. Vedovati³, C. Becattini³, G. Frisullo⁴, V. Forte⁵, T. Pirozzi¹, L. Di Gennaro¹, M. Basso¹, E. De Candia¹ | ¹Unit of Haemostasis and Thrombosis Diseases, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy; ²Department of Clinical Internal, Anesthesiological and Cardiovascular Sciences, Sapienza University of Roma, Roma, Italy; ³Department of Internal and Cardiovascular Medicine and Stroke Unit, University of Perugia, Perugia, Italy; ⁴Dipartimento di Neuroscienze, Organi di Senso e Torace, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy; ⁵Hematology, Department of Biomedicine and Prevention, University of Rome Tor Vergata, Roma, Italy

  Silvia Sorrentino

  26-10-2026

  https://doi.org/10.4081/btvb.2026.752

  7

  PDF: 3

• PO027 | IGFBP-6 REGULATES PLATELET PROCOAGULANT ACTIVITY AT THE INTERFACE BETWEEN INFLAMMATION AND COAGULATION L. Bury¹, E. Falcinelli¹, E. Petito¹, L. Leijonancker², H. van Ooijen², S. Petkov², A.R.D. Coda³, C. Raucci¹, V. Fazzi¹, D. Sarnà¹, C. Becattini¹, P. Gresele¹, A. Liso⁴ | ¹Department of Medicine and Surgery, Section of Internal and Cardiovascular Medicine, University of Perugia, Perugia, Italy; ²Pixelgen Technologies AB, Stockholm, Sweden; ³C.R.E.A.T.E.-Center for Research and Innovation in Medicine, Department of Medical and Surgical Sciences, University of Foggia, Italy; ⁴Department of Medicine and Surgery, University of Perugia, Perugia and Hematology/Oncology Unit, Terni Hospital, Terni, Italy

  Loredana Bury

  26-10-2026

  https://doi.org/10.4081/btvb.2026.843

  6

  PDF: 2
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  Interaction between adenosine diphosphate receptors and protein-kinase C isoforms in platelet adhesion under flow condition

  Boris Shenkman, Ivan Budnik, Yulia Einav

  16-02-2023

  https://doi.org/10.4081/btvb.2023.51

  1879

  pdf: 486
• 

  The landscape of rare coagulation factor deficiency management in Italy: a national hemophilia center survey

  Silvia Linari, Renato Marino, Marzia Leotta, Antonio Coppola, Patrizia Di Gregorio, Augusto Bramante Federici, Flora Peyvandi, Cristina Santoro, Ezio Zanon, Rita Carlotta Santoro

  05-11-2025

  https://doi.org/10.4081/btvb.2025.369

  1350

  PDF: 218

  HTML: 133

  Appendix: 119

• PO054 | HEMOSTASIS RESTORATION AFTER SPIKE OF FACTOR V CONCENTRATE IN COMMERCIAL FACTOR V-DEPLETED PLASMA V. Marzano², R. Russo², E. Porfido¹, F. Pierantoni¹, C. Scali¹, A. Salvatore¹, A. Carlucci¹, M. Sotgiu¹, A. Caricasole¹, F. Taglieri¹ | ¹Kedrion S.p.A., Barga, Italy; ²Università degli Studi della Campania “Luigi Vanvitelli”, Caserta, Italy

  Valeria Marzano

  26-10-2026

  https://doi.org/10.4081/btvb.2026.870

  6

  PDF: 2

• CO-57 | NXT007 PROPHYLAXIS IN PEOPLE WITH HEMOPHILIA A WITH OR WITHOUT FACTOR VIII INHIBITORS: COMBINED ANALYSIS OF TWO PHASE I/II MULTIPLE-ASCENDING-DOSE STUDIES M.E. Mancuso^1|2, M. Shima³, J.M. Staber⁴, Y.C. Chen⁵, F.J. López-Jaime⁶, M.C. Shen⁷, G. Ventriglia⁸, M. Takeyama⁹, C. Schmitt⁸, Y.S. Park¹⁰, A. Kiialainen⁸, N. Mizuno¹¹, M. Niggli⁸, T. Miyake¹¹, D. Matino¹², T. Saito¹¹, V. Jiménez-Yuste¹³, R. Kobayashi¹¹, D. Hart¹⁴, K. Nogami¹⁵ | ¹Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milano, Italy; ²Center for Thrombosis and Hemorrhagic Diseases, IRCCS Humanitas Research Hospital, Rozzano, Milano, Italy; ³Thrombosis and Hemostasis Research Center, Nara Medical University, Kashihara, Nara, Japan; ⁴Stead Family Department of Pediatrics, Carver College of Medicine, University of Iowa, Iowa City, USA; ⁵Hemophilia Care and Research Center, Tri-Service General Hospital, National Defense Medical University, Taipei, Taiwan; ⁶Servicio de Hematología, Hospital Universitario Regional de Málaga / Instituto de Investigación Biomédica de Málaga (IBIMA), Málaga, Spain; ⁷Department of Internal Medicine, Changhua Christian Hospital, Changhua, Taiwan; ⁸F. Hoffmann-La Roche Ltd, Basel, Switzerland; ⁹Division of Hemophilia, National Hospital Organization, Osaka National Hospital, Osaka, Japan; ¹⁰Department of Pediatrics, Kyung Hee University Hospital at Gangdong, Seoul, South Korea; ¹¹Chugai Pharmaceutical Co., Ltd, Tokyo, Japan; ¹²McMaster University, Hamilton, Ontario, Canada; ¹³La Paz University Hospital-IdiPAZ, Autónoma University, Madrid, Spain; ¹⁴Roche Products Ltd, Welwyn Garden City, UK; ¹⁵Department of Pediatrics, Nara Medical University, Kashihara, Nara, Japan

  Maria Elisa Mancuso

  14-10-2026

  https://doi.org/10.4081/btvb.2026.667

  25

  PDF: 15

• CO19 | Hypercoagulability in wild-type transthyretin amyloidosis: evidence from whole blood thromboelastometry A. Napolitano¹, L. Spiezia¹, C. Samà¹, A. Benetti¹, G. Sinigiani², L. De Michieli², A. Cipriani², P. Simioni¹ | ¹First Chair of Internal Medicine, Department of Medicine, University Hospital of Padua; ²Department of Cardiothoracic and Vascular Sciences & Public Health, University Hospital of Padua, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.223

  592

  PDF: 10

• CO112 | LIPOPROTEIN(a) PLASMA LEVELS AND COAGULATION BIOMARKERS: RESULTS FROM A COMPREHENSIVE LABORATORY ASSESSMENT IN AN ANGIOGRAPHICALLY-CONTROLLED CARDIOVASCULAR COHORT N. Osti¹, G. Musuraca¹, M. Spizzo², P. Pattini², G. Poli³, C. Brocco¹, C. Cemin¹, A. Madaffari¹, G. Mango², F. Presa², M. Grusse⁴, P. Van Dreden⁴, A. Anesi¹, G. Lippi³, M. Del Greco¹, A. Castagna², S. Friso², A. Ferro¹, N. Martinelli² | ¹Azienda Sanitaria Universitaria Integrata del Trentino (ASUIT), Trento, Italy; ²U.O. Medicina Interna B, Dip. Medicina, Università di Verona, Italy; ³Sez. Biochimica Clinica, Università di Verona, Italy; ⁴Dep. Clinical Research, Diagnostica Stago, Gennevilliers, France

  Nicola Osti

  26-10-2026

  https://doi.org/10.4081/btvb.2026.814

  6

  PDF: 2
• 

  PO06 | ACTIVATED PLATELETS INDUCE THE FORMATION OF NEUTROPHIL EXTRACELLULAR TRAPS VIA TOLL-LIKE RECEPTOR-4 AND P-SELECTIN GLYCOPROTEIN LIGAND-1 I.C. Moschonas, A.D. Tselepis | Atherothrombosis Research Centre, University of Ioannina, Greece

  ICTHIC 2026

  16-04-2026

  https://doi.org/10.4081/btvb.2026.502

  471

  PDF: 97

• PO025 | CHARACTERIZATION OF PLATELET DYSFUNCTION IN NOONAN SYNDROME PATIENTS S. Sorrentino¹, I. Lazzareschi², A. Ferretti¹, R. Onesimo², A. Romano³, G. Zampino², C. Leoni², E. De Candia¹ | ¹UOS Piastrinopenie Congenite e Piastrinopatie, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Roma, Italy; ²UOC Pediatria, Fondazione Policlinico Universitario Agostino Gemelli IRCSS, Roma, Italy; ³UOC Oncologia Pediatrica, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Roma, Italy

  Silvia Sorrentino

  26-10-2026

  https://doi.org/10.4081/btvb.2026.841

  2

  PDF: 1
• 

  Inflammation and hemostatic system: a selection of involved clinical disorders

  Francesco Marongiu, Antonella Mameli, Silvia Marongiu, Doris Barcellona

  28-08-2026

  https://doi.org/10.4081/btvb.2026.474

  382

  PDF: 132
• 

  Iatrogenic pseudoaneurysm of inferior epigastric artery: not only a surgical complication

  Rossana Corso, Andrea Coppola, Stefano Grazioli, Cristina Dedionigi, Nicolò Tandurella, Massimo Venturini, Francesco Dentali

  14-07-2022

  https://doi.org/10.4081/btvb.2022.25

  1144

  PDF: 392

  Supplementary Video: 341

• PO143 | GENDER DIFFERENCES IN COAGULATION PROFILE IN OBSTRUCTIVE CORONARY ARTERY DISEASE: PRELIMINARY RESULTS FROM AN ANGIOGRAPHICALLY CONTROLLED COHORT STUDY N. Osti¹, G. Musuraca¹, M. Spizzo², P. Pattini², G. Mango², F. Ambrosani², G. Poli³, C. Brocco¹, C. Angheben¹, M. Donini¹, F. Presa², M. Grusse⁴, P. Van Dreden⁴, A. Anesi¹, G. Lippi³, M. Del Greco¹, A. Castagna², S. Friso², A. Ferro¹, N. Martinelli² | ¹Azienda Sanitaria Universitaria Integrata del Trentino, Trento, Italy; ²Dip. di Medicina, Università di Verona, Verona, Italy; ³Sez. di Biochimica Clinica, Università di Verona, Verona, Italy; ⁴Clinical Research, Diagnostica STAGO, Gennevillers, France

  Nicola Osti

  26-10-2026

  https://doi.org/10.4081/btvb.2026.959

  6

  PDF: 2

• CO-55 | DEVELOPMENT OF ENGINEERED LONG-ACTING BYPASSING FX VIA ALBUMIN FUSION FOR HEMOPHILIA WITH INHIBITORS A. Martucci¹, R. Tarantino¹, K.H. Aaen², M. Pinotti¹, J.T. Andersen², A. Branchini¹ | ¹Department of Life Sciences and Biotechnology, University of Ferrara, Ferrara, Italy; ²Institute of Clinical Medicine, Department of Pharmacology, University of Oslo, Norway

  Alessandro Martucci

  14-10-2026

  https://doi.org/10.4081/btvb.2026.665

  37

  PDF: 12
• 

  PO05 | DESIGN, SYNTHESIS, AND BIOLOGICAL EVALUATION OF NOVEL IMATINIB AND NILOTINIB ANALOGUES EXPRESSING ENHANCED ANTIPLATELET AND ANTICANCER ACTIVITIES D. Pantazi¹, L. Pechlivani¹, A. Kosma¹, K. Lalechou¹, M.G. Siskos², D. Alivertis³, A.D. Tselepis¹ | ¹Atherothrombosis Research Centre, Laboratory of Biochemistry, Department of Chemistry, University of Ioannina, Greece; ²Laboratory of Organic Chemistry, Department of Chemistry, University of Ioannina, Greece; ³Department of Biological Applications and Technology, University of Ioannina, Greece

  ICTHIC 2026

  16-04-2026

  https://doi.org/10.4081/btvb.2026.501

  543

  PDF: 103

• PO082 | HEMOPHILIA AND LOW BONE MINERAL DENSITY: AN OBSERVATIONAL STUDY D. Fumarulo, R. Corrado, M. Canfora, M. Mazzetti, M. Littera, D. Prisco, C. Tamburini | Internal Medicine, Careggi Hospital, University of Florence, Firenze, Italy

  Daniela Fumarulo

  26-10-2026

  https://doi.org/10.4081/btvb.2026.898

  8

  PDF: 2

• CO016 | PLATELET HYPER-REACTIVITY AND PROCOAGULANT PHENOTYPE IN ESSENTIAL THROMBOCYTHEMIA: INSIGHTS FROM ADVANCED PLATELET FUNCTION TESTING A. Pozzi, G. Rosati, C. Barale, M. Padrini, R.M. Medici, G. Ferrari, E. Mordohovich, M. Tamietti, M. Armenio, M. Geminiani, M. De Gobbi, I. Russo, A. Morotti | Dip. Scienze Cliniche e Biologiche, Torino, Italy

  Alessandro Pozzi

  26-10-2026

  https://doi.org/10.4081/btvb.2026.718

  6

  PDF: 2

• PO33 | Whole blood hypercoagulable profiles in patients with rheumatoid arthritis L. Spiezia¹, A. Giollo², C. Samà¹, A. Benetti¹, L. Di Luozzo², M. Salvato², A. Doria², P. Simioni¹ | ¹First Chair of Internal Medicine, Thrombotic and Hemorrhagic Diseases Unit, Department of Medicine, University Hospital of Padova; ²Rheumatology Unit, Department of Medicine, University Hospital of Padova, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.296

  624

  PDF: 17
• 

  Whole exome sequencing in a family with thromboangiitis obliterans

  Barbara Lunghi, Dario Balestra, Nicole Ziliotto, Giulia Pavani, Matteo Bovolenta, Patrizia Della Valle, Mirko Pinotti, Giovanna Marchetti, Armando D'Angelo, Francesco Bernardi

  28-08-2026

  https://doi.org/10.4081/btvb.2026.367

  1119

  PDF: 125

  SUPPLEMENTARY FILES: 100

• PO141 | PLASMA METABOLOMIC PROFILING IDENTIFIES PLATELET-RELATED METABOLIC CHANGES AFTER PFO CLOSURE IN MIGRAINE WITH AURA F. Marincola¹, N. Zuddas¹, F. Cannas¹, A. Becchetti², L.V. Renna³, M. Brambilla², R. Cardani³, M. Conti², K. Nallio², M. Chessa³, D. Trabattoni², V. Fanos⁴, M. Camera^2|5 | ¹Università degli Studi di Cagliari, Cagliari, Italy; ²Centro Cardiologico Monzino IRCCS, Milano, Italy; ³IRCCS Policlinico San Donato, San Donato, Milano, Italy; ⁴University Hospital of Cagliari, Cagliari, Italy; ⁵Università degli Studi di Milano, Department of Pharmaceutical Sciences, Milano, Italy

  Maria Conti

  26-10-2026

  https://doi.org/10.4081/btvb.2026.957

  8

  PDF: 2