The clinical usefulness of measuring thrombin generation

Submitted: 30 January 2023
Accepted: 7 February 2023
Published: 6 March 2023
Abstract Views: 626
PDF: 259
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Authors

  • Coenraad H. Hemker coen@hemker.nl Laboratory for Clinical Thrombosis and Haemostasis, Departments of Internal Medicine and Biochemistry, Cardiovascular Research Institute of Maastricht, Maastricht University Medical Centre, Maastricht, Netherlands.

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Dargaud Y, Negrier C, Rusen L, et al. Individual thrombin generation and spontaneous bleeding rate during personalized prophylaxis with Nuwiq®(human‐cl rh FVIII) in previously treated patients with severe haemophilia A. Haemophilia 2018;24:619-27. DOI: https://doi.org/10.1111/hae.13493
Dargaud Y, Lienhart A, Janbain M, et al. Use of thrombin generation assay to personalize treatment of breakthrough bleeds in a patient with hemophilia and inhibitors receiving prophylaxis with emicizumab. Haematologica 2018;103:e181. DOI: https://doi.org/10.3324/haematol.2017.185330
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Azar AJ, Cannegieter SC, Deckers JW, et al. Optimal intensity of oral anticoagulant therapy after myocardial infarction. J Ame Coll Cardiol 1996;27:1349-55. DOI: https://doi.org/10.1016/0735-1097(96)00020-4
Zwaveling S, Bloemen S, Castoldi E, et al. Response of thrombin generation to rivaroxaban in twin-families: influence of sex and contraceptives. Abstract 144150. ISTH congress. Montreal 2023.
Bloemen S, Hemker HC, Al Dieri R. Large inter-individual variation of the pharmacodynamic effect of anticoagulant drugs on thrombin generation. Haematologica. 2013 Apr;98:549. DOI: https://doi.org/10.3324/haematol.2012.073601
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Troy A, Anderson TS. National trends in use of and spending on oral anticoagulants among US Medicare beneficiaries from 2011 to 2019. InJAMA Health Forum 2021;2:e211693. DOI: https://doi.org/10.1001/jamahealthforum.2021.1693
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How to Cite

Hemker, C. H. (2023). The clinical usefulness of measuring thrombin generation. Bleeding, Thrombosis and Vascular Biology, 2(1). https://doi.org/10.4081/btvb.2023.62

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