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Anticoagulation in obese patients: challenges and strategies
2037PDF: 537HTML: 306XML: 191 -
PO106 | INTERACTIONS BETWEEN DIRECT ORAL ANTICOAGULANTS AND ANTIEPILEPTIC DRUGS (INTER-DOAC): A PROSPECTIVE OBSERVATIONAL STUDY A. Rafanelli1, C. Pizzanelli3, M. Biagini1, P. Chiarugi4, M. Casini4, P. Capozza5, G. Guarini5, L. Malloggi4, G. Siciliano3, R. De Caterina5|6, L. Carrozzi1|2, F. Pistelli1|2, L. Marconi2, A. Celi1|2, R. Pancani2 | 1Pulmonary Division, Dep. of Surgical, Medical and Molecular Pathology and Critical Care Medicine, University of Pisa, Pisa, Italy; 2Pulmonary Unit, Cardiothoracic and Vascular Dep., University Hospital of Pisa, Pisa, Italy; 3Neurology Unit, Dep. of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy; 4Clinical Chemistry Laboratory, Dep. of Laboratory Medicine, University Hospital of Pisa, Pisa, Italy; 5Cardiology Unit, Cardiothoracic and Vascular Dep., University Hospital of Pisa, Pisa, Italy; 6Cardiology Division, Dep. of Surgical, Medical and Molecular Pathology and Critical Care Medicine, University of Pisa, Pisa, Italy
24PDF: 9 -
CO073 | THROMBIN GENERATION PROFILE IN ELDERLY PATIENTS WITH ATRIAL FIBRILLATION: IMPACT OF ORAL ANTICOAGULANT TYPE M. Di Gioia1, M. Berteotti1|2, G. Ciarrocca Taranta2, F. Alfano1|2, F. Crudele1, F. Cesari1, A.M. Gori1|2, A. Rogolino1, B. Giusti1|2, R. Marcucci1|2 | 1Atherothrombotic Diseases, Careggi University Hospital, Firenze, Italy; 2Dep. of Experimental and Clinical Medicine, University of Florence, Italy
26PDF: 9 -
Availability of direct oral anticoagulants testing among Italian anticoagulation clinics: a rapid evolution of clinical practice On behalf of the Italian Federation of Centers for the Diagnosis of Thrombotic Disorders and the Surveillance of the Antithrombotic Therapies
874PDF: 101 -
CO08 | The utility of urine qualitative assessment for direct oral anticoagulants in routine clinical practice F. Schieppati1,2, P. Gomez-Rosas1,3, C. Ambaglio1, V. Brusegan1, Oc. Cretu1,2, E. Galimberti1, F. Zunino1, L. Barcella1, J. Harenberg4,5, A. Falanga1,2, M. Marchetti1,2 | 1Immunohematology and Transfusion Medicine, Hospital Papa Giovanni XXIII, Bergamo, Italy; 2School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy; 3Maastricht University Medical Center, Cardiovascular Research Institute Maastricht, Maastricht, The Netherlands; 4Ruprecht Karls University of Heidelberg, Germany; 5Germany DOASENSE GmbH, Heidelberg, Germany
749PDF: 21 -
PO61 | RISK FACTORS FOR INTRACRANIAL HEMORRHAGE: AN UMBRELLA REVIEW TO INFORM MACHINE LEARNING PREDICTION MODELS IN GLIOMA PATIENTS RECEIVING ANTICOAGULATION T.A. Adeyemo, S. Greenley, F. Ware, W. Jones, A. Maraveyas, F. Haque | 1Centre of Excellence for Data Science, Artificial Intelligence and Modelling DAIM, Faculty of Science and Engineering, University of Hull, UK; 2Hull York Medical School, Hull, UK; 3Academic Library Services, University of Hull, UK; 4NHS Humber Health Partnership, Hull, UK
531PDF: 115 -
Clinical characteristics, prescription patterns and clinical outcomes of patients with extended therapy with direct oral anticoagulants for unprovoked venous thromboembolism Insights from the RIETE Registry
1573PDF: 139SUPPLEMENTARY FILES: 100APPENDIX: 120 -
Bleeding complications of oral anticoagulant therapy: from ISCOAT to the START Register A memory of Gualtiero Palareti
1733PDF: 241 -
PO108 | DIRECT ORAL ANTICOAGULANTS IN PATIENTS WITH VENOUS THROMBOEMBOLISM RECEIVING LONG-TERM IMMUNOSUPPRESSIVE THERAPY AFTER LIVER AND KIDNEY TRANSPLANTATION: A SINGLE-CENTER EXPERIENCE U. Mazzarelli1, L. Agrelli1, A. Cirillo1, C. Crescenzo2, M. Triggiani1, A. Guida3 | 1Dipartimento di Medicina Interna, Università degli studi di Salerno, Italy; 2UOC Nefrologia e Trapianti di rene; 3Centro per le malattie emorragiche congenite e malattie trombotiche, AOU San Giovanni di Dio e Ruggi d'Aragona Salerno, Italy
29PDF: 9 -
PO28 | CLINICAL IMPLICATIONS OF ANTICOAGULANT DRUG INTERACTIONS WITH TARGETED AND IMMUNE THERAPIES IN ONCOLOGY: A CONTEMPORARY RISK STRATIFICATION FRAMEWORK D. Dhami1, C. Solowiej Singh 1, M. Dhami 2 | 1Abrazo Internal Medicine Residency; 2Eastern Connecticut Hematology Oncology, Norwich, CT, USA
580PDF: 102 -
PO099 | CORRELATION BETWEEN DIRECT ORAL ANTICOAGULANTS PLASMA LEVELS AND BRAIN VASCULAR EVENTS L. Riva1, M. Paolucci2, S. Forlivesi2, M. Gentile2, G. Casella1, A. Zini2, R. Marcucci3 | 1UOC Cardiologia Ospedale Maggiore AUSL Bologna, Italy; 2IRCCS Istituto delle Scienze Neurologiche di Bologna UOC Neurologia e Rete Stroke metropolitana Ospedale Maggiore AUSL Bologna, Italy; 3SOD Malattie Aterotrombotiche AOU Careggi Università degli Studi di Firenze, Italy
23PDF: 9 -
PO43 | Extended treatment with reduced dose of direct oral anticoagulants in patients with venous thromboembolism: a retrospective study A. Pannunzio1, E. Valeriani1, I.M. Palumbo1, D. Menichelli1, T. Brogi2, S. Marucci2, D. Pastori2, P. Pignatelli2 | 1Department of General Surgery and Surgical Specialty, Sapienza University of Roma; 2Department of Clinical Internal, Anesthesiological and Cardiovascular Sciences, Sapienza University of Roma, Italy
656PDF: 27 -
OC04 | DIRECT ORAL ANTICOAGULANTS PROVIDE EFFECTIVE THROMBOPROPHYLAXIS IN NEWLY DIAGNOSED MYELOMA: REAL WORLD FINDINGS FROM THE ATOMM STUDY T. Bull1, Heamstar Collaborators2, W. Wilson3, E. Ganendra4, M. Thomas5, R. Alikhan6, M. Karanth1, M. Camilleri7 | 1West Suffolk Hospital NHS Foundation Trust, UK; 2Haematology Specialty Training Audit and Research HaemSTAR Network, UK; 3University College London Clinical Trial Centre, UK; 4North West Anglia NHS Foundation Trust, UK; 5University College London Hospitals, UK; 6Cardiff and Vale University Health Board, Wales, UK; 7Cambridge University Hospitals NHS Foundation Trust, UK
628PDF: 135 -
CO090 | DIRECT ORAL ANTICOAGULANTS IN THE SECONDARY PREVENTION OF VENOUS THROMBOEMBOLISM IN PATIENTS WITH SEVERE INHERITED THROMBOPHILIA: A REAL-WORLD MULTICENTER STUDY A. Tufano1, I.L. Calcaterra1, E. Valeriani2, E. Cimino1, P. Madonna3, A. Guida4, P. Rufolo1, F. Strano1, R. Russo1, A. Casoria5, M. Amitrano5, P. Pignatelli2, M. Di Minno1 | 1Department of Clinical Medicine and Surgery, University of Naples, Federico II, Napoli, Italy; 2Department of Internal Medicine, Endocrine and Metabolic Sciences, and Infectious Diseases. Umberto I Hospital of Roma, Italy; 3Thrombotic Unit, Ospedale del Mare, Napoli, Italy; 4Center for Congenital Bleeding Disorders and Thrombosis, AOU S.Giovanni di Dio and Ruggi d'Aragona, Salerno, Italy; 5UOC Medicina Interna, AORN Moscati, Avellino, Italy
30PDF: 11 -
CO038 | PROGNOSTIC PERFORMANCE OF BLEEDING SEVERITY CLASSIFICATIONS IN HOSPITALIZED PATIENTS WITH GASTROINTESTINAL BLEEDING ON DIRECT ORAL ANTICOAGULANTS G. Maraziti, A. Vinci, M. Verso | Internal and Emergency Medicine - Stroke Unit, S. Maria della Misericordia Hospital – University of Perugia, Perugia, Italy
26PDF: 9 -
PO011 | A TWO CENTERS REAL-WORLD EXPERIENCE WITH ANTI-XA DIRECT ORAL ANTICOAGULANTS IN CANCER PATIENTS WITH UNUSUAL SITE VEIN THROMBOSIS U. Mazzarelli1, L. Agrelli1, A. Cirillo1, C. Caputo2, M. Romano2, R. Russo2, R. Guarrasi3, M. Triggiani1, A. Tufano2, A. Guida4 | 1Dipartimento di Medicina Interna, Università degli studi di Salerno, Italy; 2Dipartimento di Medicina Interna, Università degli studi di Napoli Federico II, Italy; 3UOC Clinica Oncologica; 4Centro per le malattie emorragiche congenite e malattie trombotiche AOU San Giovanni di Dio e Ruggi d'Aragona Salerno, Italy
32PDF: 8 -
CO04 | Direct oral anticoagulants in antiphospholipid syndrome: a single center real-life experience A. Hoxha1, E. Campello1, F. Ahmad2, L. Spiezia1, P. Scarinzi1, G. Gobbo1, S. Gavasso1, F. Sartorello1, C. Simion1, E. Zanon1, P. Simioni1 | 1Internal Medicine Unit, Thrombotic and Haemorrhagic Centre, Department of Medicine - DIMED; 2Department of Statistical Sciences) University of Padova, Italy
763PDF: 22 -
PO31 | Comparative analysis of anticoagulant therapy in patients over 90 years old: vitamin K antagonists versus direct oral anticoagulants G. Sottilotta1, P. Arrigo2, S. Cuzzocrea1, D. Megalizzi1, F. Luise3 | 1UOSD Microcitemie, Emostasi e Trombosi, Grande Ospedale Metropolitano di Reggio Calabria; 2Associazione Italiana Pazienti Anticoagulati, Sezione di Reggio Calabria; 3Laboratorio Analisi. Grande Ospedale Metropolitano di Reggio Calabria, Italy
598PDF: 15 -
PO81 | Direct oral anticoagulants in atypical site vein thrombosis: a single centre experience focused on cancer patients U. Mazzarelli1, A. Guida1, L. Agrelli1, M. Amato1, R. Guarrasi2, L. Santaniello2, C. Cardamone1, P. Vitale1, M. Triggiani1 | 1Centro per le Malattie Emorragiche Congenite e Malattie Trombotiche UOC Clinica Immunologica e Reumatologica AOU S. Giovanni di Dio e Ruggi d’Aragona, Salerno; 2UOC Clinica Oncologica AOU S. Giovanni di Dio e Ruggi d’Aragona, Salerno, Italy
637PDF: 23 -
PO13 | Monitoring of anti-factor XA activity levels in patients treated with direct oral anticoagulants and concomitant tyrosine kinase inhibitors agents: a monocentric experience E. Santacroce1,2, C. Santoro1, E. Baldacci1, S. Ligia1, R. Mormile1, M. Biglietto1, M. Totaro1, F. R. Mauro1, M. Breccia1, A. Chistolini1 | 1Department of Translational and Precision Medicine, Haematology, Sapienza University of Roma; 2Department of Clinical and Molecular Medicine, Sapienza University of Roma, Italy
649PDF: 20 -
CO050 | INTERACTION BETWEEN DIRECT ORAL ANTICOAGULANTS AND ANTIEPILEPTIC DRUGS: A MULTICENTER OBSERVATIONAL STUDY A. Lipari1, S. Sorrentino1, M. De Siati1, L. D'Innocenzo1, A. Ferretti1, D. Menichelli2, V. Cammisotto2, P. Pignatelli2, G. Ragna3, MC. Vedovati3, C. Becattini3, G. Frisullo4, V. Forte5, T. Pirozzi1, L. Di Gennaro1, M. Basso1, E. De Candia1 | 1Unit of Haemostasis and Thrombosis Diseases, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy; 2Department of Clinical Internal, Anesthesiological and Cardiovascular Sciences, Sapienza University of Roma, Roma, Italy; 3Department of Internal and Cardiovascular Medicine and Stroke Unit, University of Perugia, Perugia, Italy; 4Dipartimento di Neuroscienze, Organi di Senso e Torace, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy; 5Hematology, Department of Biomedicine and Prevention, University of Rome Tor Vergata, Roma, Italy
31PDF: 13 -
PO26 | OUTCOMES OF DIRECT ORAL ANTICOAGULANTS IN UNUSUAL-SITE THROMBOSIS: IMPACT OF ACTIVE CANCER S. Guglielmo1, M. Lovisotto1, L. Scarano1, E. De Bon2, S. Barbar2 | 1Internal Medicine, Department of Medicine, Azienda Ulss 6 Euganea, Cittadella (PD), Italy; 2Thrombotic and Hemorrhagic Disorders Unit, Department of Medicine, Azienda Ulss 6 Euganea, Cittadella (PD), Italy
517PDF: 109 -
PO103 | THE EFFECT OF ALBUMIN ON SERUM CONCENTRATION OF DIRECT ORAL ANTICOAGULANTS: A CROSS-SECTIONAL STUDY A. Pannunzio1, E. Valeriani2, I.M. Palumbo1, V. Cammisotto3, S. Bartimoccia3, V. Castellani3, S. Marucci3, D. Pastori3, D. Menichelli3, P. Pignatelli3 | 1Dip. di Chirurgia generale, specialistica ed anestesiologia - Università degli studi di Roma La Sapienza, Italy; 2Dip. di Medicina Interna, Scienze Endocrino-metaboliche e Malattie Infettive - Università degli Studi di Roma La Sapienza, Italy; 3Dip. di Medicina e Scienze Cardiovascolari - Università degli Studi di Roma La Sapienza, Italy
23PDF: 8 -
CO042 | BLEEDING RISK IN PATIENTS RECEIVING CONCURRENT TREATMENT WITH DIRECT ORAL ANTICOAGULANTS AND CORTICOSTEROIDS: A SYSTEMATIC REVIEW M.A. Capparella1, R. Talerico2, C. Cavallaro2, M. Iorio2, F. Bossi1, A. Porfidia2, K. Abe3, M. Biglietto4, A. Chistolini4, A. Holt5, L. Lahousse6|7, R. Pola2, C. Becattini1, M.C. Vedovati1 | 1Internal, Vascular and Emergency Medicine – Stroke Unit, University of Perugia, Italy; 2Thrombosis Unit, Department of Geriatric, Orthopedic, and Rheumatologic Sciences, Fondazione Policlinico A. Gemelli IRCCS, Roma, Italy; 3Division of Gastroenterology, Department of Medicine, Teikyo University School of Medicine, Tokyo, Japan; 4Hematology, Department of Translational and Precision Medicine, Sapienza University of Roma, Italy; 5Department of Cardiology, Copenhagen University Hospital – Herlev and Gentofte, Copenhagen, Denmark; 6Department of Bioanalysis, Pharmaceutical Care Unit, Faculty of Pharmaceutical Sciences, Ghent University, Ghent, Belgium; 7Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands
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PO83 | A case of deep vein thrombosis in a patient with systemic mastocytosis M. Leotta, A. Ierardi, A. Strangio, R C. Santoro | UO Emofilia, Emostasi e Trombosi, AOU R Dulbecco, Catanzaro
757PDF: 23 -
PO140 | HISTORY OF FALLS IN PATIENTS WITH ATRIAL FIBRILLATION: A SYSTEMATIC REVIEW AND META-ANALYSIS A.P. Speziale1, G. Buoninfante1, A. Ronca2|4, B. Corica3, V. Trapani1, M. Moretti1, G. Annecchini1, R. Cangemi1, V. Raparelli1, M. Proietti2|4, S. Basili1, G.F. Romiti5 | 1Department of Translational and Precision Medicine, Sapienza University of Roma, Roma, Italy; 2Department of Clinical Sciences and Community Health, University of Milano, Milano, Italy; 3University of Modena and Reggio Emilia, Modena, Italy; 4Division of Subacute Care, IRCCS Istituti Clinici Scientifici Maugeri, Milano, Italy; 5Department of Wellbeing, Health and Environmental Sustainability, Sapienza University of Roma, Rieti, Italy
25PDF: 7 -
CO09 | Long term effectiveness and safety of direct oral anticoagulants in patients with factor V Leiden and/or prothrombin gene mutation and venous thromboembolism: a single centre, retrospective cohort study I.M. Palumbo1, E. Valeriani1,2, A. Pannunzio1, S. Marucci3, D. Menichelli1, D. Pastori3,4, P. Pignatelli3 | 1Department of General Surgery and Surgical Specialty, Sapienza University of Roma; 2Department of Infectious Disease, Azienda Ospedaliero-Universitaria Policlinico Umberto I, Roma; 3Department of Clinical Internal, Anaesthesiologic and Cardiovascular Sciences, Sapienza University of Roma; 4IRCCS Neuromed, Pozzilli, Italy
759PDF: 26 -
PO156 | DIRECT ORAL ANTICOAGULANTS FOR THE TREATMENT OF VTE IN PATIENTS WITH CANCER: A SURVEY AMONG CAMPANIAN INTERNAL MEDICINE WARDS E. Marrone1, C. Arturo2, F. Cannavacciulo3, D. D’Ambrosio4, F. Gallucci1, M. Amitrano3, C. Di Gennaro2, P. Morella1, A. Maffettone5 | 1UOC Medicina 3, AORN A Cardarelli, Napoli, Italy; 2UOC Medicina Generale, PO A. Rizzoli, Ischia, Italy; 3UOC Medicina Interna, AO Moscati, Avellino, Italy; 4UOC Medicina Generale, PO Piedimonte Matese ASL Caserta, Italy; 5UOC Medicina interna, PO San Luca, Vallo Della Lucania ASL Salerno, Italy
26PDF: 7 -
PO104 | BLEEDING AND THROMBOTIC OUTCOMES DURING EXTENDED DIRECT ORAL ANTICOAGULANT THERAPY: AN EIGHT YEAR RETROSPECTIVE ANALYSIS G. Sottilotta1, G. Praticò1, S. Cuzzocrea1, D. Megalizzi1, F. Luise2 | 1UOSD Microcitemie - Emostasi e Trombosi. Grande Ospedale Metropolitano di Reggio Calabria, Italy; 2Laboratorio Analisi. Grande Ospedale Metropolitano di Reggio Calabria, Italy
28PDF: 10 -
CO041 | GLOBAL COAGULATION ASSESSMENT FOR THE RISK OF HEAVY MENSTRUAL BLEEDING IN WOMEN ON ORAL ANTICOAGULANT THERAPY – THE COHMBO STUDY M. Abbattista, E. Scalambrino, M. Clerici, A. Truma, A. Artoni, P. Bucciarelli | Fondazione IRCCS Ca' Granda Policlinico, Italy
37PDF: 10 -
OC06 | PRIMARY THROMBOPROPHYLAXIS IN ADVANCED PANCREATIC DUCTAL ADENOCARCINOMA UNDERGOING SYSTEMIC ANTICANCER TREATMENT: A CANCER-CENTER COHORT STUDY ON CLINICAL PRACTICE AND OUTCOMES F. Haque1|2, A. Adekeye1|2, Z. Mohtashim2, K. Page1, M. Goodman1, A. Maraveyas 1|2 | 1Hull University Teaching Hospital NHS Trust, UK; 2Hull York Medical School, UK
485PDF: 106 -
PO005 | EXTENDED ANTICOAGULATION WITH DOACS IN PATIENTS AFFECTED BY HEMATOLOGIC MALIGNANCIES AND VENOUS THROMBOEMBOLISM: DOES LOW DOSE FIT ALL? M. Biglietto, S. Sorella, L.V. Cappelli, B. Mandelli, D. Kasmi, E. Baldacci, A. Chistolini | Sapienza University of Roma, Italy
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PO53 | Effectiveness and safety of DOACS in patients with renal transplantation A. Ierardi, A. Strangio, M. Leotta, R C. Santoro | UO Emofilia, Emostasi e Trombosi, AOU Renato Dulbecco, Catanzaro, Italy
647PDF: 17 -
PO77 | The clinical awareness of mixing test interpretation in the era of complex reporting algorithm: do we forget the origins? A. Fassina, L. De Valentin, S. Luzi, R. Turrini, A. Antico, L. Zardo | Laboratorio Analisi Castelfranco Veneto, ULSS Marca Trevigiana, Italy
635PDF: 16 -
PO002 | VENOUS THROMBOEMBOLISM IN PATIENTS WITH FACTOR VII DEFICIENCY: A CASE SERIES AND REVIEW OF THE LITERATURE BM. Roccon1, MI. Tassoni1, G. Quintavalle1, F. Riccardi1, A. Matichecchia1, GF. Rivolta1, M. Lombardi3, R. Rossi2, A. Benegiamo2, A. Tagliaferri1, A. Coppola1 | 1SSD Centro Hub Emofilia e Malattie Emorragiche Congenite, Azienda Ospedaliero-Universitaria di Parma, Italy; 2Lab. di Coagulazione, UOC Diagnostica Ematochimica, Azienda Ospedaliero-Universitaria di Parma, Italy; 3Centro Emostasi, UOC Medicina Interna ad indirizzo angiologico e coagulativo, Azienda Ospedaliero-Universitaria di Parma, Italy
26PDF: 11 -
PO57 | Direct oral anticoagulant determination in urine samples compared to plasma concentrations in outpatients with atrial fibrillation and obesity A. Pannunzio1, I.M. Palumbo1, D. Menichelli1, V. Cammisotto2, V. Castellani3, E. Baldacci4, R. Mormile4, A. Chistolini4, G. Bernardini5, N. Porcu1, D. Pastori2, J. Harenberg6, F. Violi2, P. Pignatelli2 | 1Department of General Surgery, Surgical Specialties and Organ Transplantation Paride Stefanini, Sapienza University of Roma, Italy; 2Department of Clinical Internal, Anesthesiological and Cardiovascular Sciences, Sapienza University of Roma, Italy; 3Department of Translational and Precision Medicine, Sapienza University of Roma, Italy; 4Department of Hematology, Oncology and Dermatology, Sapienza University of Roma, Italy; 5U.O.S.D. Medicina Rigenerativa DAI, Medicina Diagnostica e Radiologia, Policlinico Umberto 1, Roma, Italy; 6Ruprecht Karls University of Heidelberg, Germany
551PDF: 16 -
PO18 | Does muscle mass matter? Appendicular lean mass as a determinant of anti-XA activity in elderly patientes B.M. Zanforlini1, V. Bernardi1, E. Campello2, E.M. Bicego1, C. Curreri1, A. Vaticano1, C. Sartori1, L. Manfron1, A. Perencin1, P. Rollo1, A. Baruffol1, L. Ruoso1, C. Simion2, C. Bulato2, P. Berto2, P. Simioni2, G. Sergi1 | 1Department of Medicine, Geriatrics Section, University of Padova; 2Haemorrhagic and Thrombotic Diseases Unit, Department of Medicine DIMED, Padova University Hospital, Padova, Italy
600PDF: 16 -
PO31 | MIGRATORY SUPERFICIAL THROMBOPHLEBITIS REFRACTORY TO APIXABAN IN A PATIENT WITH LUNG ADENOCARCINOMA I. Goldberg1|2, P. Raanani1|2|3, G. Spectre1|2 | 1Institute of Hematology, Beilinson Hospital, Rabin Medical Center, Petah Tikva, Israel; 2Faculty of Medical & Health Sciences, Tel Aviv University, Tel Aviv, Israel; 3Felsenstein Medical Research Center, Rabin Medical Center, Petah Tikva, Israel
501PDF: 100 -
PO116 | MONOCENTRIC EXPERIENCE OF DOACS REVERSAL MANAGEMENT AT L SACCO HOSPITAL, MILAN: A REAL-WORLD RETROSPECTIVE STUDY A. Veltroni, C. Sitzia, O. Di Bartolo, IM Burgo, MC. Carraro, S. Crivelli, C. Masseroni, GB. Inghilleri | Medicina Trasfusionale, Ospedale L. Sacco, Milano, Italy
19PDF: 8 -
PO70 | Clinical safety and monitoring of apixaban combined with tacrolimus and everolimus in kidney transplant patients: a prospective study S. Guglielmo1, E. De Bon2, L. Scarano1, R. Fabris1, E. Pierobon3, S. Barbar2 | 1Internal Medicine, Department of Medicine, Azienda ULSS 6 Euganea, Cittadella; 2Thrombotic and Hemorrhagic Disorders Unit, Department of Medicine, Azienda ULSS 6 Euganea, Cittadella; 3Nephrology and Dialysis Unit, Azienda ULSS 6 Euganea, Cittadella and Camposampiero, Padova, Italy
640PDF: 25 -
PO93 | Use of DOACS in heart transplantation recipients T. Marrazzo1, A. Delle Femine1, C. Amarelli2, R. Albisinni3 | 1UOC Medicina Interna e dei Trapianti, Ospedale Monaldi Azienda dei Colli, Napoli; 2UOSD CCH dei Trapianti, Ospedale Monaldi Azienda dei Colli, Napoli; 3UOC CCH Generale, Ospedale Monaldi Azienda dei Colli, Napoli, Italy
747PDF: 17 -
PO30 | LONG-TERM ANTICOAGULANT THERAPY AND PREVENTION OF RECURRENT VENOUS THROMBOEMBOLISM IN ADVANCED OVARIAN CANCER V. Bitsadze 1, A. Vorobev 1, J. Khizroeva 1, A. Solopova 1, M. Tretyakova 1, N. Gashimova 1, K. Grigoreva 1, A. Khisamieva 1, J. Gris 1|2, I. Elalamy1|3|4, G. Gerotziafas1|3|4, A. Makatsariya1 | 1Department of Obstetrics, Gynecology and Perinatal Medicine, N. F. Filatov Clinical Institute of Children’s Health, I. M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia; 2Faculty of Pharmaceutical and Biological Sciences, Montpellier University, France; 3Department Hematology and Thrombosis Center, Medicine Sorbonne University, Paris, France; 4Hospital Tenon, Paris, France
473PDF: 98 -
PO37 | Single centre experience on anticoagulation in carriers of non-mild inherited thrombophilia: direct oral anticoagulants (DOAC) efficacy and safety M. D’uva1,2, G. La Barba1, G. Montanaro1, M. Di Ianni1,2, P. Ranalli1,2 | 1Hematology Unit, S. Spirito Hospital, Pescara; 2Department of Medicine and Aging Sciences, D’Annunzio University, Chieti, Italy
651PDF: 22 -
CO039 | CLINICAL SAFETY AND MONITORING OF APIXABAN IN HEMODIALYSIS PATIENTS: A PROSPECTIVE STUDY S. Guglielmo1, M. Lovisotto1, E. De Bon2, E. Pierobon3, S. Barbar2 | 1Internal Medicine, Department of Medicine; 2Thrombosis and Haemostasis Unit, Department of Medicine; 3Nephrology and Dialysis Unit, Azienda Ulss 6 Euganea, Cittadella and Camposampiero, Padova, Italy
28PDF: 11 -
PO89 | Apixaban for secondary prevention of venous thromboembolism in hemodialysis patients: pharmacokinetic profile and safety outcomes S. Guglielmo1, E. De Bon2, L. Scarano1, R. Fabris1, E. Pierobon3, S. Barbar2 | 1Internal Medicine, Department of Medicine; 2Thrombotic and Hemorrhagic Disorders Unit, Department of Medicine; 3Nephrology and Dialysis Unit, Azienda ULSS 6 Euganea, Cittadella and Camposampiero, Padua, Italy
854PDF: 15 -
PO29 | CANADIAN INSIGHTS INTO THE MANAGEMENT OF BREAKTHROUGH THROMBOSIS S. Ramdani1, C. Séguin2 | 1Division of Hematology, Post-Graduate Medical Education Program, McGill University, Montreal; 2Division of Hematology, Department of Medicine, McGill University Health Center, Montreal, Canada
491PDF: 97 -
PO130 | HEMORRHAGIC AND THROMBOTIC COMPLICATIONS DURING DOACS TREATMENT: THE IMPORTANCE OF A REGULAR AND PROLONGED FOLLOW-UP D. Barcellona1|2, A. Mameli2, S. Cornacchini2, P. Schirru2, L. Fenu2, V. Casu2, F. Marongiu1|2 | 1University of Cagliari, Italy; 2Haemostasis and Thrombosis Unit, Azienda Ospedaliero-Universitaria di Cagliari, Italy
32PDF: 6 -
CO070 | PLASMIN GENERATION AND ITS INTERPLAY WITH COAGULATION AND FIBRINOLYSIS IN ATRIAL FIBRILLATION: IMPACT OF ANTICOAGULANT THERAPY G. Ciarrocca Taranta1, F. Alfano1, M. Di Gioia2, M. Berteotti1|2, E. Lotti2, F. Cesari2, A. Rogolino2, F.A. Barbuto1, A. M Gori1|2, E. Sticchi1|2, B. Giusti1|2, R. Marcucci1|2 | 1Dep of Experimental and Clinical Medicine, University of Florence, Italy; 2Atherothrombotic Diseases, Careggi University Hospital, Firenze, Italy
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OC03 | THROMBOEMBOLIC PREVALENCE IN MULTIPLE MYELOMA BEFORE AND AFTER THE INTRODUCTION OF DIRECT ORAL ANTICOAGULANTS: A LONGITUDINAL COHORT STUDY A. Ramírez1, A. Orozco2, A. Sánchez3, F. Villalpa1, S. Burgos2, G. Cesarman3, G. Rodríguez1, D. Vieyra2, J. Álvarez4, G.M. Flores3, S. González1, D. Martínez2, B. Cabello3, R. Espinoza3, O. Fernández3 | 1Myeloma-clinic Hematology service, Centro Médico Nacional La Raza, Instituto Mexicano del Seguro Social, México City, México; 2Myeloma-clinic Hematology service, Instituto Nacional de Nutrición Salvador Zubirán, México City, México; 3Myeloma-clinic Hematology service, Instituto Nacional de Cancerologçia, México City, Mexico; 4Centro Médico Nacional 20 de Noviembre, México City, Mexico
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PO105 | IMPACT OF ECOG PERFORMANCE STATUS ON CANCER-ASSOCIATED THROMBOSIS TREATED WITH DOACS: DATA FROM A MULTICENTER COHORT STUDY R. Talerico1, F. Mancinetti1, C. Sacco2, M. Mazzetti3, E. Campello4, S. Birocchi5, S. Beccatini6, A. Porfidia1, C. Lodigiani2, P. Simioni4, G.M. Podda5, I. Mastandrea2, C. Becattini6, R. Pola1, M.C. Vedovati6 | 1Thrombosis Unit, Department of Geriatric, Orthopedic, and Rheumatologic Sciences, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy; 2Thrombosis and Hemorrhagic Diseases Unit, IRCCS Humanitas Research Hospital, Rozzano, Milano, Italy; 3Interdisciplinary Internal Medicine, Careggi University Hospital, Firenze, Italy; 4First Chair of Internal Medicine and Thrombotic and Hemorrhagic Diseases Unit, Department of Medicine, University of Padova, Italy; 5Medicine II Unit, ASST Santi Paolo e Carlo, Department of Health Sciences, University of Milano, Milano, Italy; 6Internal, Vascular and Emergency Medicine– Stroke Unit, University of Perugia, Perugia, Italy
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CO037 | PERFORMANCE OF A QUALITATIVE POINT-OF-CARE TEST IN PATIENTS EXPERIENCING ACUTE THROMBOEMBOLIC OR MAJOR BLEEDING EVENTS TREATED WITH DOACs: THE T-BLEEDOAC MULTICENTER PROSPECTIVE COHORT STUDY M. Vedovati1, G. Pepe2, S. Vanni3, E. Campello4, F. Morello5, S. Beccatini1, D. Giudici1, F. Lucarini2, L. Parmeggiani3, G. Fabiani3, P. Simioni4, M. Santoro5, P. Nazerian6, M. Mosconi1, C. Becattini1 | 1University of Perugia, Perugia, Italy; 2Versilia Hospital, Tuscany North West Health System, Lido di Camaiore (LU), Italy; 3Università di Firenze, Firenze, Italy; 4University of Padua, Padova, Italy; 5A.O.U. Città della Salute e della Scienza, Torino, Italy; 6Careggi University Hospital, Firenze, Italy
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PO47 | VENOUS THROMBOEMBOLISM IN BREAST CANCER: INSIGHTS FROM A SINGLE-CENTER COHORT S. Kozhukhov, N. Dovganych | SI “NSC “The M. D. Strazhesko Institute of Cardiology, Clinical and Regenerative Medicine of the National Academy of Medical Sciences of Ukraine, Kyiv, Ukraine; 2Cardio-Oncology Center, Kyiv, Ukraine
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PO27 | URINE QUALITATIVE ASSESSMENT OF DIRECT ORAL ANTICOAGULANTS IN ROUTINE CLINICAL PRACTICE F. Schieppati1|2, P. Gomez-Rosas1|3, C. Ambaglio1, V. Brusegan1, O.C. Cretu1, E. Galimberti1, F. Zunino1, L. Barcella1, J. Harenberg4|5, A. Falanga1|2, M. Marchetti1|2 | 1Immunohematology and Transfusion Medicine, Hospital Papa Giovanni XXIII, Bergamo, Italy; 2School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy; 3Maastricht University Medical Center, Cardiovascular Research Institute Maastricht, Maastricht, The Netherlands; 4Ruprecht Karls University of Heidelberg, Heidelberg, Germany; 5DOASENSE GmbH, Heidelberg, Germany
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CO015 | EVOLUTION OF ANTICOAGULANT THERAPY FOR CANCER-ASSOCIATED THROMBOSIS: THE START2 REGISTRY ONCO-VTE LONGITUDINAL STUDY M. Marchetti1|2, T. Zollner1|2, O.C. Cretu1|2, A. Chistolini3, R. Pancani4, L. Puccetti5, P. Sivera6, W. Ageno7, G. Elmi8, V. Fregoni9, V. Tonelli10, E. Antonucci11, D. Poli11|12, A. Falanga1|2, L. Barcella1|2 | 1Hemostasis & Thrombosis Center, Department of Transfusion Medicine, Papa Giovanni XXIII Hospital, Bergamo, Italy; 2ERN EuroBloodNet; 3Hematology Unit, Department of Translational and Precision Medicine, Sapienza University of Roma, Roma, Italy; 4Pulmonary Unit, Hospital of Siena, University of Siena, Siena, Italy; 5Hemostasis and Thrombosis Unit, Hospital of Siena, University of Siena, Siena, Italy; 6Haematology Unit, Ordine Mauriziano Hospital, Torino, Italy; 7Department of Medicine, University of Padua, Padova, Italy; 8Department of Medicine, Maggiore Hospital, Bologna, Italy; 9Department of Medicine, Sondalo Hospital, Sondalo, Italy; 10Angiology Unit, Sant'Eugenio Hospital, Roma, Italy; 11Arianna Anticoagulazione Foundation, Bologna, Italy; 12Department of Critical Care Medicine, Thrombosis Centre, Azienda Ospedaliera Universitaria Careggi, Firenze, Italy
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PO003 | CATHETER-RELATED THROMBOSIS IN CANCER PATIENTS: A RETROSPECTIVE REAL-WORLD STUDY G. Autiero1|3, S.A. Malerba1|2|4, F. Busato1|2, D. Tolomio1|2, M. Dalla Vestra1|2, F. Presotto1|2 | 1U.O. Medicina Generale, Osp. Dell'Angelo, Venezia-Mestre, Italy; 2U.O. Angiologia, Osp. Dell'Angelo, Venezia-Mestre, Italy; 3Dip. Medicina Interna, Università degli Studi di Padova, Italy; 4U.O.C. Medicina Generale ad indirizzo trombotico ed emorragico, Università degli studi di Padova, Italy
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PO40 | RADAR, UK-MRA MYELOMA XV - COMPARING MRD-GUIDED TREATMENT ESCALATION AND DE-ESCALATION STRATEGIES IN PATIENTS WITH NEWLY DIAGNOSED MYELOMA SUITABLE FOR STEM CELL TRANSPLANTATION: THROMBOPROPHYLAXIS SUBGROUP STUDY PROTOCOL Z. Sayar, on behalf of the RADAR Investigators | Whittington Health NHS Trust and Royal Free Hospital, London, UK
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PO124 | BLEEDING COMPLICATIONS DURING ANTICOAGULATION WITH DOACS FOR NVAF AND THEIR MOST COMMON RISK FACTORS A. delle Femine, P. Di Micco, P. Sommese, M. Di Napoli, A. Di Salvatore, M. Galdiero, A. Lobasso, R. Serpico, V. Brunelli, A. Di Fusco, C. di Gennaro | U.O.C. Medicina Interna, Osp. Santa Maria delle Grazie, Pozzuoli, Italy
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PO34 | INVESTIGATORS’ DECISIONS ON ANTICOAGULATION AFTER EXTENDED API-CAT TREATMENT FOR CANCER VENOUS THROMBOEMBOLISM I. Mahé1|4, F. Happe2, M. Monreal5|7, H. Robert-Ebadi8, P. Debourdeau9, J. R. Fabreguettes10, S. Accassat11, P. Mismetti4|11|12, P. Girard13, S. Laporte4|12|14, C. Chapelle14 | 1Paris Cité University; 2Assistance Publique - Hôpitaux de Paris, Louis Mourier Hospital, Department of Internal Medicine; 3Inserm UMR-S970, Paris Cardiovascular Research Center, Team « Endotheliopathy and Hemostasis Disorders », Paris, France; 4F-CRIN INNOVTE Network, France; 5Department of Internal Medicine, Institut de Recerca Germans Trias i Pujol, Hospital Universitari Germans Trias i Pujol, Badalona, Spain; 6Department of Medicine, Universitat Autonoma de Barcelona, Barcelona; 7Universidad Catolica San Antonio de Murcia, Murcia, Spain; 8Division of Angiology and Hemostasis, Faculty of Medicine, Geneva University Hospitals, Geneva, Switzerland; 9Arles Hospital, Oncology unit, Arles, France; 10Assistance Publique - Hôpitaux de Paris, AGEPS, France; 11Service de Médecine Vasculaire et Therapeutique, CHU de Saint-Etienne, Saint-Etienne, France; 12Université Jean Monnet, Mines Saint-Étienne, INSERM Unité 1059, Santé Ingénierie Biologie Saint-Étienne SAINBIOSE, Saint-Étienne, France; 13Département de Pneumologie, Institut Mutualiste Montsouris, Paris; 14Service de Pharmacologie Clinique, CHU de Saint-Etienne, Saint-Etienne, France
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CO05 | Long-term management of upper extremity catheter-related thrombosis in female patients with cancer: a retrospective cohort study Chiara Cavallaro1,2, Paolo Santini1,2, Laura Leoni3, Carolina Mosoni1,2, Silvia D’Ambrosio1,2, Francesco Mancinetti1,2, Nicola Coletta1,2, Michela Iorio1,2, Angelo Porfidia1,2, Alessandro D’Errico1,2, Rosa Talerico1,2, Roberto Pola1,2 | 1Department of Aging, Orthopedic, and Rheumatologic Sciences, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome; 2Università Cattolica del Sacro Cuore, Rome; 3Vita-Salute University, San Raffaele Hospital IRCCS, Milan, Italy
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PO067 | LONG‑TERM SAFETY AND EFFECTIVENESS OF VITAMIN K ANTAGONISTS IN PATIENTS WITH ANTIPHOSPHOLIPID ANTIBODIES: A RETROSPECTIVE COHORT ANALYSIS G. Sottilotta1, G. Praticò1, D. Megalizzi1, F. Luise2 | 1UOSD Centro per le Microcitemie - Servizio Emostasi e Trombosi; 2Laboratorio Analisi, Grande Ospedale Metropolitano di Reggio Calabria, Italy
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PO72 | Fondaparinux in patient with active tuberculosis T. Marrazzo1, R. Parrella2, A. Botta2, A. Pontarelli2, M.P. Ursi3, A. Karruli4, R. Albisinni5 | 1UOC Medicina Interna e dei Trapianti, Ospedale Monaldi, Napoli, Italy; 2UOC Malattie Infettive ad Indirizzo Respiratorio, Ospedale Cotugno Azienda dei Colli, Napoli, Italy; 3UOC MECAU Ospedale CTO Azienda dei Colli, Napoli, Italy; 4Malattie Infettive e Tropicali, Ospedale di Tirana, Albania; 5UOC CCH Generale, Ospedale Monaldi Azienda dei Colli, Napoli, Italy
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PO21 | PSYCHOLOGICAL IMPACT OF CANCER-ASSOCIATED THROMBOSIS: DUAL BURDEN AND IMPLICATIONS FOR QUALITY OF LIFE AND INTEGRATED PATIENT-CENTERED CARE G. Gerotziafas1|4, Y. Mitrou5, M. Marchetti6, P. Las Casa1, A. Tafur7, V. Bitsadze3, J. Khizroeva3, D. Taizhanova8, D. Antic9, C. Frére10, A. Makatsariya3, L. Garderet1|11, A. Escargueil1, C. Ay12, N. Lomatkin13, Z. Tazi-Mezalek14, M. Sassi15, M. Catalano4|16, J. Gligorov1|17, J. Caprini18, P. Van Dreden1|19, J. Fareed2, A. Falanga6 | 1Sorbonne University, INSERM UMR_S_938, CRSA, Research Department "Cancer, Vessels, Biology and Therapeutics" (CaVITE), Research Group "Cancer-Angiogenesis-Thrombosis and Haemostasis," Thrombosis Center, University Institute of Cancerology (UIC), Saint Antoine University Hospital Assistance Publique Hôpitaux de Paris (AP-HP)Paris France; 2Center of Translational Research and Education, Department of Pathology and Laboratory Medicine, Loyola University Stritch School of Medicine, Maywood, Chicago, USA; 3Thrombosis Center, Department of Obstetrics, Gynecology and Perinatal Medicine, The I. M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia; 4VAS-European Independent Foundation in Angiology/Vascular Medicine Milan Italy; 5Department of Phylosophy, National and Kapodistrian University of Athens, Greece; 6Department of Immunohematology and Transfusion Medicine, Hospital Papa Giovanni XXIII, Bergamo, Italy. School of Medicine and Surgery, University of Milan Bicocca, Milan, Italy; 7Vascular Medicine, Endeavor Health, Evanston, IL, USA; Pritzker School of Medicine, University of Chicago, Chicago, IL 60637, USA; 8Department of Internal Diseases, Karaganda Medical University Non-Commercial Joint Stock Company, Karaganda, Kazakhstan; 9Clinic for Hematology, University Clinical Center of Serbia, Faculty of Medicine University of Belgrade Belgrade Serbia; 10Department of Hematology, Pitié-Salpêtrière Hospital, Assistance Publique-Hôpitaux de Paris, Sorbonne Université, INSERM UMRS-1166 Institute of Cardiometabolism and Nutrition, Paris, France; 11Clinical Haematology Department, Sorbonne Université, Pitié-Salpêtrière Hospital, APHP, Paris; 12Department of Internal Medicine I, Clinical Division of Haematology and Haemostaseology, Medical University of Vienna, Vienna, Austria; 13Cardiology Division, Central Clinical Hospital of Presidential Administration, Moscow, Russia; 14Department of Internal Medicine, Hématologie Clinique, Centre Hospitalo-Universitaire Ibn Sina, Université Mohammed V de Rabat, Rabat, Morocco; 15Hematology Laboratory of Maternity and Neonatal Center of Monastir, Faculty of Pharmacy of Monastir, Monastir, Tunisia; 16Inter-University Research Center on Vascular Diseases, University of Milan-L Sacco Hospital, Milan, Italy; 17Medical Oncology Department, Tenon Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Sorbonne University, Paris, France; 18Vascular Surgery, Pritzker School of Medicine at the University of Chicago, Chicago, USA; 19Clinical Research, Diagnostica Stago, Gennevilliers, France
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