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• CO-22 | CLINICAL FEATURES IN PATIENTS WITH NON-SEVERE HEMOPHILIA A: THE DISCOVERY SCORE PROPOSAL FOR PROPHYLAXIS PRESCRIPTION M.N.D. Di Minno¹, E. Baldacci², C. Biasoli³, A. Borchiellini⁴, F. Daniele⁵, P. Di Gregorio⁶, C. Gorio⁷, G. Malcangi⁸, E. Marchesini⁹, I. Ricca¹⁰, R. Santoro¹¹, S. Siragusa¹², M.R. Villa¹³, E. Zanon¹⁴, A. Tagliaferri¹⁵, A. Coppola¹⁵ | ¹Hub Centre for Thrombotic and Hemorrhagic Disorders, Federico II University Hospital, Napoli, Italy; ²Haematology, University Hospital Policlinico Umberto I, Roma, Italy; ³Interdepartmental Simple Structure for the Management of Hemorrhagic and Thromboembolic Diseases, M. Bufalini Hospital, Cesena, Italy; ⁴Regional Centre for Hemorrhagic and Thrombotic Diseases, AOU Città della Salute e della Scienza, Torino, Italy; ⁵Haemostasis and Thrombosis Service, Ospedale Civile dell'Annunziata, Cosenza, Italy; ⁶Transfusion Medicine Department, "SS. Annunziata" Hospital, Chieti, Italy; ⁷Pediatric Onco-Hematology Unit, Children's Hospital, ASST-Spedali Civili, Brescia, Italy; ⁸Haemophilia and Thrombosis Center, University Hospital Policlinico-Giovanni XXIII, Bari, Italy; ⁹Hemophilia Centre, SC Vascular and Emergency Department, University of Perugia, Italy; ¹⁰Centro Emofilia, Città della Salute e della Scienza, Torino, Italy; ¹¹Hemostasis and Thrombosis Unit, Azienda Ospedaliero Universitaria Dulbecco, Catanzaro, Italy; ¹²Centro di Riferimento Regionale per le Emocoagulopatie Congenite, Palermo, Italy; ¹³Hematology Unit, Ospedale Santa Maria di Loreto, Napoli, Italy; ¹⁴Hemophilia and Thrombosis Center, University Hospital of Padua, Italy; ¹⁵Hemophilia and Thrombosis Center, Azienda Ospedaliera di Parma, Italy

  Matteo Di Minno

  14-10-2026

  https://doi.org/10.4081/btvb.2026.632

  31

  PDF: 9

• CO-21 | FUSION 2: VALIDATION AND CLINICAL PERFORMANCE OF AN INTEGRATED ULTRASOUND–FUNCTIONAL ASSESSMENT SYSTEM IN HEMOPHILIA M.E. Susi¹, E.A. Boccalandro², A. Giuffrida³, I. Ricca⁴, P. Imazio⁵, E. Bonetti⁶, I. Nichele⁷ B. Pollio⁸, E. Zanon⁹, E. Baldacci¹⁰, C. Santoro¹⁰, G. Delios⁴, S. Ligia¹⁰, M. Biglietto¹⁰, I. Calcaterra¹¹, M. Napolitano¹², M. Bodini², C. Simion⁹, B. Borsellino⁸, G. Pasta¹³, M.N.D. Di Minno¹¹, C. Martinoli^14|15 | ¹DIMES, Department of Experimental Medicine, University of Genoa, Italy; ²Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center and Fondazione Luigi Villa, Milano, Italy; ³Hemophilia Center, Borgo Roma Hospital, Integrated University Hospital of Verona, Italy; ⁴Immunology and Transfusion Medicine Service, Hemophilia Center, Ivrea Hospital, Local Health Authority TO4, Ivrea, Italy; ⁵Rehabilitation and Functional Recovery Service, Pediatric Orthopedics Unit, Regina Margherita Children’s Hospital, City of Health and Science University Hospital of Turin, Italy; ⁶Pediatric Oncohematology Unit, Borgo Trento Hospital, Integrated University Hospital of Verona, Italy; ⁷Haemophilia and Thrombosis Center, Haematology Department, San Bortolo Hospital, Vicenza, Italy; ⁸Transfusion Medicine and Immunohematology Service, Regina Margherita Children’s Hospital, City of Health and Science University Hospital of Turin, Italy; ⁹Coagulation Disorders and Hemophilia Center, University Hospital of Padova, Italy; ¹⁰Unit of Special Diagnosis and Therapy of Hemostasis and Thrombosis, Hematology Department, Policlinico Umberto I, Sapienza University of Rome, Italy; ¹¹Department of Clinical Medicine and Surgery, Regional Reference Centre for Coagulation Disorders, Federico II University, Napoli, Italy; ¹²Dipartimento PROMISE, Università degli Studi di Palermo and UOC Ematologia e Malattie Rare, PO “Cervello”, Palermo, Italy; ¹³Orthopedics and Traumatology Clinic, IRCCS Policlinico San Matteo Foundation, Pavia, Italy; ¹⁴DISSAL, Department of Health Sciences, University of Genoa, Italy; ¹⁵UOC Emergency and Musculoskeletal Radiology, IRCCS AOM San Martino Hospital, Genova, Italy

  Maria Elena Susi

  14-10-2026

  https://doi.org/10.4081/btvb.2026.631

  22

  PDF: 10

• CO-37 | STEW-EFA STUDY: MULTICENTER EVALUATION OF ONE-STAGE AND CHROMOGENIC ASSAYS FOR EFANESOCTOCOG ALFA MEASUREMENT ON STAGO AND WERFEN PLATFORMS A.C. Molinari¹, M. Marchetti², A. Catalano³, L. Contino⁴, R. De Cristofaro⁵, A.B. Federici⁶, T. Martini⁷, I. Quaglia⁸, R. Rossi⁹, R. Santoro¹⁰, A. Tripodi¹¹, A. Valpreda¹² | ¹Regional Reference Centre for Hemorrhagic Diseases, Department of Hemato-Oncology, IRCCS Istituto Giannina Gaslini, Genova, Italy; ²Department of Immunohematology and Transfusion Medicine, ASST Papa Giovanni XXIII, Bergamo, Italy; ³Società per la Promozione dell'educazione Medica (S.P.E.Me), Italy; ⁴Hemostasis and Thrombosis Unit, AOU SS Antonio e Biagio e C Arrigo, Alessandria, Italy; ⁵Dipartimento di Medicina e Chirurgia Traslazionale, Facoltà di Medicina e Chirurgia "Agostino Gemelli," Università Cattolica S. Cuore, Roma, Italy - Servizio Malattie Emorragiche e Trombotiche, Fondazione Policlinico Universitario "A. Gemelli" Istituto di Ricerca e Cura a Carattere Scientifico, Roma, Italy; ⁶School of Medicine and Surgery, University of Milan-Bicocca, Milano, Italy; ⁷Hemophilia Centre, Immune-Hematology and Transfusion Medicine, University Hospital “Città della Salute e della Scienza", Torino, Italy; ⁸Center for Thrombosis and Hemorrhagic Diseases, IRCCS Humanitas Research Hospital Rozzano, Milan, Italy; ⁹Laboratory of Clinical Chemistry and Hematology, University Hospital of Parma, Italy; ¹⁰Hemophilia, Hemostasis, and Thrombosis Unit, Azienda Ospedaliero Universitaria Dulbecco, Catanzaro, Italy; ¹¹IRCCS Ca' Granda Maggiore Hospital Foundation and Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Milano, Italy; ¹²Central Laboratory Baldi and Riberi, AOU Città della Salute e della Scienza, Turin, Italy, reference laboratory of the Regional Center for Hemostasis and Thrombosis.

  Angelo Claudio Molinari

  14-10-2026

  https://doi.org/10.4081/btvb.2026.647

  23

  PDF: 11

• CO-67 | CONGENITAL DYSFIBRINOGENEMIA: BLEEDING PHENOTYPE, THROMBOTIC COMPLICATIONS, AND LONG-TERM MANAGEMENT IN A MULTICENTER COHORT M. Biglietto^1|2, M. Presti¹, R.C. Santoro³, I. Nichele⁴, M. Napolitano⁵, S. Pasca⁶, A. Borchiellini⁷, B. Pollio⁸, E. Zanon⁹, G. Barillari¹⁰, A. Poz¹⁰, S. Sorella¹, S. Ligia¹, R. Mormile¹, E. Baldacci¹, G. Castaman¹¹, F. Peyvandi^12|13, C. Santoro¹ | ¹Hematology, Department of Translational and Precision Medicine, Sapienza University of Rome, Italy; ²Department of Molecular Biology, Sapienza University of Rome, Italy; ³Hemostasis and Thrombosis Unit, Azienda Ospedaliera Pugliese-Ciaccio, Catanzaro, Italy; ⁴Hematology Unit, Azienda ULSS 8 Berica - San Bortolo Hospital, Vicenza, Italy; ⁵Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, University of Palermo, Italy; ⁶Coagulation Diseases Center, Transfusion Medicine Department - Azienda Sanitaria Universitaria Integrata del Trentino, Trento, Italy; ⁷Centro di Riferimento Regionale Malattie Emorragiche e Trombotiche dell'Adulto, Divisione di Ematologia, Università Città della Salute e della Scienza di Torino, Italy; ⁸SIMT Immunohematology and Transfusion Medicine Service, Diagnostic Department, A.O. Città della Salute e della Scienza, Torino, Italy; ⁹Department of Medicine, Haemophilia Centre, University Hospital of Padua, Italy; ¹⁰Center for Hemorrhagic and Thrombotic Diseases, General and University Hospital S. Maria della Misericordia, Udine, Italy; ¹¹Centre for Bleeding Disorders and Coagulation, Careggi University Hospital, Firenze, Italy; ¹²IRCCS Fondazione Ca' Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Milano, Italy; ¹³Università degli Studi di Milano, Department of Pathophysiology and Transplantation, Milano, Italy

  Mario Biglietto

  14-10-2026

  https://doi.org/10.4081/btvb.2026.677

  25

  PDF: 11

• CO-70 | CONGENITAL AFIBRINOGENEMIA: BLEEDING PHENOTYPE, THROMBOTIC COMPLICATIONS, AND LONG-TERM MANAGEMENT IN A MULTICENTER COHORT M. Biglietto^1|2, M. Presti¹, R.C. Santoro³, I. Nichele⁴, M. Napolitano⁵, S. Pasca⁶, A. Borchiellini⁷, B. Pollio⁸, E. Zanon⁹, G. Barillari¹⁰, A. Poz¹⁰, S. Sorella¹, S. Ligia¹, R. Mormile¹, E. Baldacci¹, G. Castaman¹¹, F. Peyvandi^12|13, C. Santoro¹ | ¹Hematology, Department of Translational and Precision Medicine, Sapienza University of Rome, Italy; ²Department of Molecular Biology, Sapienza University of Rome, Italy; ³Hemostasis and Thrombosis Unit, Azienda Ospedaliera Pugliese-Ciaccio, Catanzaro, Italy; ⁴Hematology Unit, Azienda ULSS 8 Berica - San Bortolo Hospital, Vicenza, Italy; ⁵Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, University of Palermo, Italy; ⁶Coagulation Diseases Center, Transfusion Medicine Department - Azienda Sanitaria Universitaria Integrata del Trentino, Trento, Italy; ⁷Centro di Riferimento Regionale Malattie Emorragiche e Trombotiche dell'Adulto, Divisione di Ematologia, Università Città della Salute e della Scienza di Torino, Italy; ⁸SIMT Immunohematology and Transfusion Medicine Service, Diagnostic Department, A.O. Città della Salute e della Scienza, Torino, Italy; ⁹Department of Medicine, Haemophilia Centre, University Hospital of Padua, Italy; ¹⁰Center for Hemorrhagic and Thrombotic Diseases, General and University Hospital S. Maria della Misericordia, Udine, Italy; ¹¹Centre for Bleeding Disorders and Coagulation, Careggi University Hospital, Firenze, Italy; ¹²IRCCS Fondazione Ca' Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Milano, Italy; ¹³Università degli Studi di Milano, Department of Pathophysiology and Transplantation, Milano, Italy

  Mario Biglietto

  14-10-2026

  https://doi.org/10.4081/btvb.2026.680

  20

  PDF: 12
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  The landscape of rare coagulation factor deficiency management in Italy: a national hemophilia center survey

  Silvia Linari, Renato Marino, Marzia Leotta, Antonio Coppola, Patrizia Di Gregorio, Augusto Bramante Federici, Flora Peyvandi, Cristina Santoro, Ezio Zanon, Rita Carlotta Santoro

  05-11-2025

  https://doi.org/10.4081/btvb.2025.369

  1343

  PDF: 216

  HTML: 133

  Appendix: 119
• 

  PO25 | EVOLUTION OF ANTICOAGULANT STRATEGIES AND CLINICAL OUTCOMES IN CANCER-ASSOCIATED THROMBOSIS: A LONGITUDINAL ANALYSIS OF THE START2 REGISTRY ONCO-VTE M. Marchetti^1|2, T. Zollner^1|2, OC. Cretu^1|2, A. Chistolini³, R. Pancani⁴, L. Puccetti⁵, P. Sivera⁶, W. Ageno⁷, G. Elmi⁸, V. Fregoni⁹, V. Tonelli¹⁰, E. Antonucci¹¹, D. Poli^11|12, A. Falanga^1|2, L. Barcella^1|2 | ¹Hemostasis & Thrombosis Center, Department of Transfusion Medicine, Papa Giovanni XXIII Hospital, Bergamo Italy; ²ERN EuroBloodNet; ³Hematology Unit, Department of Translational and Precision Medicine, Sapienza University of Rome, Rome, Italy; ⁴Pulmonary Unit, Hospital of Siena, University of Siena, Siena, Italy; ⁵Hemostasis and Thrombosis Unit, Hospital of Siena, University of Siena, Siena, Italy; ⁶Haematology Unit, Ordine Mauriziano Hospital, Turin, Italy; ⁷Department of Medicine, University of Padua, Padua, Italy; ⁸Department of Medicine, Maggiore Hospital, Bologna, Italy; ⁹Department of Medicine, Sondalo Hospital, Sondalo, Italy; ¹⁰Angiology Unit, Sant'Eugenio Hospital, Rome, Italy; ¹¹Arianna Anticoagulazione Foundation, Bologna, Italy; ¹²Department of Critical Care Medicine, Thrombosis Centre, Azienda Ospedaliera Universitaria Careggi, Firenze, Italy

  ICTHIC 2026

  16-04-2026

  https://doi.org/10.4081/btvb.2026.520

  427

  PDF: 88
• 

  Still unmet problems with low molecular weight heparin prophylaxis of venous thromboembolism. An Italian survey

  Stefania Cavazza, Gualtiero Palareti*

  03-10-2025

  https://doi.org/10.4081/btvb.2025.177

  1443

  PDF: 303

  HTML: 201

  Supplementary: 102
• 

  Anticoagulation in obese patients: challenges and strategies

  Alice Lipari, Esmeralda Capristo, Antonietta Ferretti, Erica De Candia

  18-09-2025

  https://doi.org/10.4081/btvb.2025.174

  2022

  PDF: 522

  HTML: 302

  XML: 185

• CO-11 | MAPPING THE COMPETENCIES OF NURSES IN ITALIAN HEMOPHILIA CENTERS: CURRENT STATUS AND PERSPECTIVES FOR THE IDENTIFICATION OF NURSE-SENSITIVE OUTCOMES M.V. Puliga¹, A.C. Ferrini², C. Manzi³, D. Meneghini⁴, E. Tosi⁴, P. Berto⁵, M. Amelotti-Botta⁶, E. Quercio⁶, M.E. Mancuso⁷, R.C. Santoro⁸ | ¹SODc Malattie Emorragiche e della Coagulazione, AOU Careggi, Firenze, Italy; ²SSI Malattie Emorragiche e Tromboemboliche, Osp. Bufalini, Cesena, Italy; ³SSD Malattie Emorragiche Congenite, IRCCS Policlinico Sant'Orsola, Bologna, Italy; ⁴Centro Emofilia e UOC Medicina Trasfusionale, AOU Integrata, Verona, Italy; ⁵Centro Emofilia Hub, AO di Padova, Italy; ⁶SSD Emostasi e Coordinamento Malattie Rare, AO SS. Antonio e Biagio, Alessandria, Italy; ⁷UOC Centro Trombosi e Malattie Emorragiche, IRCCS Humanitas Research Hospital, Rozzano, Milano, Italy; ⁸UOD Emofilia, Emostasi e Trombosi, AOU Renato Dulbecco, Catanzaro, Italy

  Maria-Virginia Puliga

  14-10-2026

  https://doi.org/10.4081/btvb.2026.621

  66

  PDF: 10

• CO-45 | BRIDGING THE CLINICAL CHASM: GENETIC ANALYSIS AS A CONFIRMATORY TOOL IN MISMATCHED GLANZMANN THROMBASTHENIA R. Pastorino^1|3, F. Bocchi^1|3, A. Valpreda⁴, G. Murante^1|2|3, S. Bergonzi^1|2|3, M. Capetta^1|2|3, F. Valeri^1|2, C. Dainese^1|2, M. Gilestro⁵, D. Peruccio⁶, E. De Candia⁷, P. Concolino⁸, B. Bruno^2|3, A. Borchiellini^1|2 | ¹Regional Centre for Hemorrhagic and Thrombotic Diseases, AOU Città della Salute e della Scienza, Italy; ²Division of Hematology, AOU Città della Salute e della Scienza and University of Turin, Italy; ³Department of Molecular Biotechnology and Health Sciences, University of Turin, Italy; ⁴Central Laboratory Baldi and Riberi, AOU Città della Salute e della Scienza di Torino, Italy; ⁵AOU Citta' della Salute e della Scienza, PO Molinette, Anatomy and Pathological Histology 1 U, Department of Laboratory Medicine - Flow Cytometry Laboratory, Torino, Italy; ⁶AOU Citta' della Salute e della Scienza di Torino, Maternal-Infant and Trauma Transfusion Medicine, Regina Margherita Hospital, Department of Laboratory Medicine, Torino, Italy; ⁷Haemostasis and Thrombosis Unit, Fondazione Policlinico Universitario A.Gemelli, IRCCS, Department of Translational Medicine, Università Cattolica del Sacro Cuore, Roma, Italy; ⁸Fondazione Policlinico Universitario A. Gemelli, IRCCS, Department of Laboratory and Hematological Sciences, Unit of Clinical Chemistry, Biochemistry and Molecular Biology, UOSD of Molecular and Genomic Diagnostics, Roma, Italy

  Rebecca Pastorino

  14-10-2026

  https://doi.org/10.4081/btvb.2026.655

  23

  PDF: 6

• CO02 | Hepatic fibrosis as predictor of cancer-associated thrombosis in patients with intrahepatic cholangiocarcinoma Y. Frion-Herrera^1,2, C. Venturin^1,3, M. Cadamuro⁴, J. Gasparello⁵, C.M. Radu¹, M. Fassan⁵, C. Mescoli⁶, U. Cillo⁷, E. Gringeri⁷, G. Zanus⁸, L. Fabris^1,3, P. Simioni¹ | ¹Clinical Medicine and Thrombotic and Haemorrhagic Disease Unit, and Haemophilia Center, Padua University-Hospital, Department of Medicine [DIMED], University of Padua, Italy; ²Department of Biology [DiBio], University of Padua, Italy; ³Department of Internal Medicine, Digestive Disease Section, Liver Center, Yale University, New Haven, CT, USA; ⁴School of Medicine and Surgery, University of Milan-Bicocca, Milan, Italy; ⁵Department of Pathology Ca’ Foncello Hospital, ULSS2 Marca Trevigiana, Italy; ⁶Pathology Unit, Padua University-Hospital, Padua, Italy; ⁷Hepatobiliary Surgery and Liver Transplantation Unit, Padua University-Hospital, Department of Surgery, Oncology and Gastroenterology [DISCOG], University of Padua, Italy; ⁸General Surgery Unit, Ca’ Foncello Hospital, ULSS2 Marca Trevigiana, Department of Surgery, Oncology and Gastroenterology [DISCOG], University of Padua, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.207

  710

  PDF: 26

• CO-61 | REAL-WORLD IMPLEMENTATION OF GENE THERAPY FOR HEMOPHILIA: A SHARED PATHWAY AMONG HEALTHCARE AUTHORITY, SPECIALIST CENTERS AND PATIENT ORGANIZATIONS IN THE EMILIA-ROMAGNA REGION A. Coppola¹, L. Valdrè², C. Biasoli³, E. Ferri Grazzi⁴, E. Rozzi⁵, M. Volta⁵, R. Giroldini⁶, A. Tagliaferri¹ | ¹SSD Centro Hub Emofilia e Malattie Emorragiche Congenite, Azienda Ospedaliero-Universitaria di Parma, Italy; ²SSD Malattie Emorragiche Congenite, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Italy; ³SSI Presa in Carico delle Malattie Emorragiche e Tromboemboliche, AUSL Romagna, Ospedale Bufalini, Cesena, Italy; ⁴FEDRED, Federazione delle Associazioni Emofilici della Regione Emilia Romagna, Italy; ⁵Servizio Assistenza Ospedaliera, Malattie Rare, Direzione Generale Cura della Persona, Salute e Welfare, Regione Emilia Romagna, Italy; ⁶Area Governo del Farmaco e Dispositivi Medici, Direzione Generale Cura della Persona, Salute e Welfare, Regione Emilia Romagna, Italy

  Antonio Coppola

  14-10-2026

  https://doi.org/10.4081/btvb.2026.671

  20

  PDF: 9

• CO-02 | NEONATAL GENOMIC SCREENING ENABLES PRE-SYMPTOMATIC DIAGNOSIS AND PREVENTIVE MANAGEMENT OF HEMOPHILIA B. Borsellino¹, B. Pollio¹, P. Quarello^2|3, T. Martini¹, C. Linari⁴, M. Carabotta⁵, C. Cagnazzo², S. Minucci⁶, F. Fagioli^2|3 | ¹Paediatric Haemophilia Centre, Immune-Haematology and Transfusion Medicine, University Hospital "Città della Salute e della Scienza", Torino, Italy; ²Paediatric Onco-Hematology, Stem Cell Transplantation and Cellular Therapy Division, Regina Margherita Children’s Hospital, Torino, Italy; ³Department of Paediatric and Public Health Sciences, University of Turin, Italy; ⁴Department of Laboratory Medicine, Azienda Ospedaliera Universitaria Città della Salute e della Scienza, Torino, Italy; ⁵Department of Pediatrics, G. d'Annunzio University, Chieti, Italy; ⁶Italian Institute for Genomic Medicine, IRCCS, Candiolo, Italy

  Beatrice Borsellino

  14-10-2026

  https://doi.org/10.4081/btvb.2026.612

  68

  PDF: 12

• CO-01 | BLEEDING EVENTS IN MILD HEMOPHILIA A AND VON WILLEBRAND DISEASE TYPE 1 YEARLY TREATABLE WITH DESMOPRESSIN IN ITALY A. Gringeri^1|2, P.M. Mannucci³, G.C. Castaman⁴, F. Peyvandi^3|5 | ¹Fondazione Charta, Milano, Italy; ²Centro di Sanità Solidale, Lucca, Italy; ³Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center and Fondazione Luigi Villa, Milano, Italy; ⁴Centre for Bleeding Disorders and Coagulation, Careggi University Hospital, Firenze, Italy; ⁵Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Italy

  Alessandro Gringeri

  14-10-2026

  https://doi.org/10.4081/btvb.2026.611

  65

  PDF: 12
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  The key to fibrinolysis and thrombolysis

  Roger Lijnen, Désiré Collen

  09-09-2025

  https://doi.org/10.4081/btvb.2025.368

  1684

  PDF: 521

  HTML: 261

• CO41 | Failure in assisted reproductive techniques: insights from the first registry E. Grandone^1,3,4, C. Lodigiani², D. Colaizzo³, M. Passaretti², J. Khizroeva⁴, A. De Laurenzo³, P. Totaro⁵, E. Bucherini⁶, D. Baldini⁷, V. Bitsadze⁴, A. Makatsarya⁴, M. Mastroianno³, G. Piazza⁸, M. Othman⁹, M. Margaglione¹ | ¹University of Foggia, Italy; ²Humanitas University, Rozzano, Italy; ³IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy; ⁴First Sechenov University, Russia; ⁵Santa Maria Hospital, Bari, Italy; ⁶Angiologia, Faenza, Italy; ⁷Momo Fertilife, Bisceglie, Italy; ⁸Brigham Women Hospital, USA; ⁹Queen’s University, Kingston, Canada

  22-10-2025

  https://doi.org/10.4081/btvb.2025.310

  571

  PDF: 13

• CO-07 | ITALIAN RESOURCE USE IN MILD HEMOPHILIA A AND TYPE 1 VON WILLEBRAND DISEASE A. Gringeri^1|2, G.C. Castaman³ | ¹Fondazione Charta, Milano, Italy; ²Centro di Sanità Solidale, Lucca, Italy; ³Centre for Bleeding Disorders and Coagulation, Careggi University Hospital, Firenze, Italy

  Alessandro Gringeri

  14-10-2026

  https://doi.org/10.4081/btvb.2026.617

  67

  PDF: 12
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  A commitment to global collaboration, welcoming international participation and advancing science for the benefit of patients

  Pantep Angchaisuksiri, Wolfram Ruf, Jeffrey Weitz, Sam Schulman, Guy A. Young

  01-07-2025

  https://doi.org/10.4081/btvb.2025.188

  1634

  PDF: 333

  HTML: 126

• PO41 | Comparison of the haemorrhagic phenotype between female and male patients affected by autosomal inherited bleeding disorders in a single-centre cohort B. Borsellino^1,3, C. Zuccotti², L. Guarnera^3,4, C. Biasoli⁵, P. Pedrazzi⁵, T. Martini¹ | ¹Haemophilia Centre, Immune-Haematology and Transfusion Medicine, University Hospital “Città della Salute e della Scienza”, Turin, Italy; ²Department of Clinical Pathology, Bufalini Hospital, Cesena, Italy; ³Department of Biomedicine and Prevention, PhD in Immunology, Molecular Medicine and Applied Biotechnology, University of Roma Tor Vergata, Roma, Italy; ⁴Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH, USA; ⁵Haemophilia and Transfusion Centre, Bufalini Hospital, Cesena, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.304

  607

  PDF: 21
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  When a feminist platelet went to the convention of prostaglandins and thromboxanes

  Giovanni de Gaetano

  04-11-2025

  https://doi.org/10.4081/btvb.2025.412

  1255

  PDF: 163

  HTML: 186

  Italian version: 104

• CO-47 | JOINT ULTRASOUND FOLLOW-UP IN PEDIATRIC PATIENTS WITH HEMOPHILIA: A 12-YEAR PROSPECTIVE SINGLE-CENTER EXPERIENCE I. Ricca¹, B. Borsellino^2|3, T. Martini², C. Martinoli⁴, B. Pollio² | ¹Transfusion Medicine, Ivrea Hospital, Ivrea, Italy; ²Haemophilia Centre, Immune-Haematology and Transfusion Medicine, University Hospital “Città della Salute e della Scienza”, Torino, Italy; ³Department of Biomedicine and Prevention, PhD in Immunology, Molecular Medicine and Applied Biotechnology, University of Rome Tor Vergata, Roma, Italy; ⁴Department of Health Science DISSAL, University of Genova, Unit of Radiology and IRCCS San Martino Hospital, Genova, Italy

  Tiziano Martini

  14-10-2026

  https://doi.org/10.4081/btvb.2026.657

  23

  PDF: 12
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  Gene therapy for hemophilia B

  Pier Mannuccio Mannucci

  12-12-2025

  https://doi.org/10.4081/btvb.2025.425

  683

  PDF: 91

  HTML: 105
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  Platelet distribution width is associated with cardiovascular mortality in an adult general population

  Benedetta Izzi, Simona Costanzo, Alessandro Gialluisi, Amalia De Curtis, Sara Magnacca, Teresa Panzera, Augusto Di Castelnuovo, Maria Benedetta Donati, Chiara Cerletti, Marc F. Hoylaerts, Giovanni de Gaetano, Licia Iacoviello, *on behalf of the Moli-sani Study Investigators

  27-09-2023

  https://doi.org/10.4081/btvb.2023.83

  3079

  PDF: 507

  Supplementary Material: 142

• PO57 | Direct oral anticoagulant determination in urine samples compared to plasma concentrations in outpatients with atrial fibrillation and obesity A. Pannunzio¹, I.M. Palumbo¹, D. Menichelli¹, V. Cammisotto², V. Castellani³, E. Baldacci⁴, R. Mormile⁴, A. Chistolini⁴, G. Bernardini⁵, N. Porcu¹, D. Pastori², J. Harenberg⁶, F. Violi², P. Pignatelli² | ¹Department of General Surgery, Surgical Specialties and Organ Transplantation Paride Stefanini, Sapienza University of Roma, Italy; ²Department of Clinical Internal, Anesthesiological and Cardiovascular Sciences, Sapienza University of Roma, Italy; ³Department of Translational and Precision Medicine, Sapienza University of Roma, Italy; ⁴Department of Hematology, Oncology and Dermatology, Sapienza University of Roma, Italy; ⁵U.O.S.D. Medicina Rigenerativa DAI, Medicina Diagnostica e Radiologia, Policlinico Umberto 1, Roma, Italy; ⁶Ruprecht Karls University of Heidelberg, Germany

  22-10-2025

  https://doi.org/10.4081/btvb.2025.326

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• CO-12 | BEYOND CLOTTING FACTORS: NURSING AS A CORNERSTONE OF LIFELONG HEMOPHILIA CARE M.V. Puliga¹, C. Manzi², A. Besagni³, S. Linari¹, C. Carulli⁴, M. Morfini⁵ | ¹SODc Malattie Emorragiche e della Coagulazione, AOU Careggi, Firenze, Italy; ²SSD Malattie Emorragiche Congenite, IRCCS Policlinico Sant'Orsola, Bologna, Italy; ³Indipendente, Italy; ⁴Clinica Ortopedica, Università di Firenze, SOD Ortopedia, AOU Careggi, Firenze, Italy; ⁵Associazione Italiana Centri Emofilia, AICE, Milano, Italy

  Maria-Virginia Puliga

  14-10-2026

  https://doi.org/10.4081/btvb.2026.622

  70

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• 

  Diagnostic and management practices for inherited fibrinogen disorders: a nationwide survey of Italian Hemophilia Treatment Centers

  Renato Marino, Silvia Linari, Marzia Leotta, Antonio Coppola, Chiara Biasoli, Maria Elisa Mancuso, Flora Peyvandi, Cristina Santoro, Ezio Zanon, Rita Carlotta Santoro

  02-12-2025

  https://doi.org/10.4081/btvb.2025.372

  909

  PDF: 118

  HTML: 121

  Supplementary: 78

  Appendix: 79

• CO-44 | EVALUATION OF THE DEVIATION BETWEEN PRESCRIBED AND RECOMMENDED EMICIZUMAB DOSING IN PATIENTS WITH CONGENITAL HEMOPHILIA A A.C. Giuffrida¹, S. Abeysinghe Gunawardhana¹, S. Amato², F. Casoli², C. Recchi², M. Saggioro², E. Bonetti³, M. Bodini¹, G. Poli² | ¹Centro Emofilia, UOC Medicina Trasfusionale, AOUI Verona, Italy; ²UOC Laboratorio Analisi, AOUI Verona, Italy; ³UOC Oncoematologia Pediatrica, AOUI Verona, Italy

  Marco Bodini

  14-10-2026

  https://doi.org/10.4081/btvb.2026.654

  25

  PDF: 9
• 

  Persistence of functional anti-PF4 antibodies and neutrophil activation in vaccine-induced immune thrombotic thrombocytopenia

  Eleonora Petito, Anna Maria Mezzasoma, Emanuela Falcinelli, Chiara Conti, Erica De Candia, Raimondo De Cristofaro, Silvia Sorrentino, Gian Marco Podda, Mariangela Scavone, Anna Falanga, Marina Marchetti, Luca Barcella, Stefania Basili, Lucia Stefanini, Andrea Boccatonda, Laura Contino, Patrizia Sciancalepore, Igor Florio, Egidio Imbalzano, Rossella Marcucci, Angela Rogolino, Patrizia Noris, Marta Panella, Rita Santoro, Maria Costanza Turi, Gaetano Vaudo, Rosa Curcio, Paolo Gresele

  18-11-2025

  https://doi.org/10.4081/btvb.2025.400

  948

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  HTML: 201

• CO-04 | INTEGRATING EXPERTISE: IMPLEMENTATION OF A MULTIDISCIPLINARY PATHWAY FOR GENETIC TESTING AND COUNSELLING IN INHERITED BLEEDING DISORDERS E. Zacchi^1|2, L. Piscitelli¹, C. Manzi¹, L. Godino², F. Riccardi³, A. Vaisfeld^2|4, L. Valdrè¹ | ¹Inherited Bleeding Disorders Unit, IRCCS AOUBO, Bologna, Italy; ²Medical Genetics Unit, IRCCS AOUBO, Bologna, Italy; ³Regional Hub Centre for Hemophilia and Inherited Bleeding Disorders, University Hospital of Parma, Italy; ⁴Department of Medical and Surgical Sciences, University of Bologna, Italy

  Eliana Zacchi

  14-10-2026

  https://doi.org/10.4081/btvb.2026.614

  64

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• PO88 | Bacterial lysate “lantigen B” induces proliferation of B and NK cells and the release of related cytokines M. Alfonsetti¹, R. Liani¹, P. Di Mattia³, M. Tredicine⁴, F. Papa³, Q. Niu⁵, M. Di Gioacchino², F. Santilli^1,3 | ¹Department of Medicine and Aging, Center for Advanced Studies and Technology, University of Chieti, Italy; ²Institute for Clinical Immunotherapy and Advanced Biological Treatments, Pescara, Italy; ³Specialization School of Allergy and Clinical Immunology, G. d’Annunzio University, Chieti, Italy; ⁴Department of Medical, Oral, and Biotechnology Science, University G. d’Annunzio, Chieti-Pescara, Chieti, Italy; ⁵Department of Occupational Health, School of Public Health, Shanxi Medical University, Taiyuan, Shanxi, China

  22-10-2025

  https://doi.org/10.4081/btvb.2025.358

  725

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• CO-88 | TRANSIENT IDIOPHATIC ACQUIRED VON WILLEBRAND DISEASE: A RARE, CHALLENGING CONDITION WITH A POSSIBLE RAPID AND FAVORABLE EVOLUTION G. Murante^1|2|3, S. Bergonzi^1|2|3, M. Capetta^1|2|3, F. Valeri^1|2, C. Dainese^1|2, A. Valpreda⁴, R. Pastorino^1|3, F. Bocchi^1|3, B. Bruno^2|3, A. Borchiellini^1|2 | ¹Regional Centre for Hemorrhagic and Thrombotic Diseases, AOU Città della Salute e della Scienza of Turin, Italy; ²Division of Hematology, AOU Città della Salute e della Scienza, University of Turin, Italy; ³Dep. of Molecular Biotechnology and Health Sciences, University of Turin, Italy; ⁴Central Lab. Baldi and Riberi, AOU Città della Salute e della Scienza of Turin, Italy

  Giovanni Murante

  14-10-2026

  https://doi.org/10.4081/btvb.2026.698

  23

  PDF: 14

• CO-24 | BALANCING BLEEDING AND THROMBOSIS: SAFETY OF LOW-MOLECULAR-WEIGHT HEPARIN THROMBOPROPHYLAXIS IN PATIENTS WITH HEMOPHILIA UNDERGOING MAJOR SURGERY S. Bergonzi^1|2|3, G. Murante^1|2|3, M. Capetta^1|2|3, F. Valeri^1|2, C. Dainese^1|2, A. Valpreda^3|4, R. Pastorino^3|4, F. Bocchi^3|4, B. Bruno^2|3, A. Borchiellini^1|2 | ¹Regional Centre for Hemorrhagic and Thrombotic Diseases, AOU Città della Salute e della Scienza, Torino, Italy; ²Division of Hematology, AOU Città della Salute e della Scienza, University of Turin, Italy; ³Department of Molecular Biotechnology and Health Sciences, University of Turin, Italy; ⁴Central Laboratory Baldi and Riberi, AOU Città della Salute e della Scienza, University of Turin, Italy

  Sara Bergonzi

  14-10-2026

  https://doi.org/10.4081/btvb.2026.634

  25

  PDF: 9
• 

  Bioequivalence of von Willebrand factor-containing concentrates: implications for the choice in patients with von Willebrand disease. A position paper from the Italian Association of Hemophilia Centers

  Ezio Zanon, Giancarlo Castaman, Augusto Bramante Federici, Maria Elisa Mancuso, Gianfranco Pasut, Alberto Tosetto, Angiola Rocino, Rita Carlotta Santoro

  26-01-2026

  https://doi.org/10.4081/btvb.2026.415

  1285

  PDF: 342

  HTML: 163

• CO-43 | VALIDATION OF THROMBIN GENERATION MEASUREMENT IN PLATELET-RICH PLASMA: EVOLUTION IN THE ST GENESIA^® SYSTEM F. Bocchi^1|2, R. Pastorino^1|2, G. Murante^1|2|3, S. Bergonzi^1|2|3, M. Capetta^1|2|3, F. Valeri^2|3, C. Dainese^2|3, A. Valpreda⁴, B. Bruno^1|3, A. Borchiellini^2|3 | ¹Department of Molecular Biotechnology and Health Sciences, University of Turin, Italy; ²Regional Centre for Thrombotic and Hemorrhagic Diseases, AOU Città della salute e della Scienza di Torino, Italy; ³Division of Hematology, AOU Città della Salute e della Scienza, University of Turin, Italy; ⁴Central Lab Baldi and Riberi, AOU Città della salute e della Scienza di Torino, Italy

  Francesca Bocchi

  14-10-2026

  https://doi.org/10.4081/btvb.2026.653

  17

  PDF: 11

• CO-68 | ACQUIRED FACTOR XIII DEFICIENCY ASSOCIATED WITH CROHN’S DISEASE: A CHALLENGING DIAGNOSTIC AND THERAPEUTIC CASE A. Colombo¹, A. Dal Buono^2|3, I. Quaglia¹, C. Novembrino⁴, M.R. Fasulo¹, C. Lodigiani¹, M.E. Mancuso^1|2 | ¹Center for Thrombosis and Hemorrhagic Diseases, IRCCS Humanitas Research Hospital, Rozzano, Milano, Italy; ²Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milano, Italy; ³IBD Center, IRCCS Humanitas Research Hospital, Rozzano, Milano, Italy; ⁴Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico Angelo Bianchi Bonomi, Hemophilia and Thrombosis Center and Fondazione Luigi Villa, Milano, Italy

  Arianna Colombo

  14-10-2026

  https://doi.org/10.4081/btvb.2026.678

  22

  PDF: 10

• CO-36 | PLATELETS MATTER: THROMBIN GENERATION IN PLATELET‐RICH-PLASMA VS. PLATELET‐POOR‐PLASMA UNDER NON-REPLACEMENT THERAPIES IN HEMOPHILIA F. Bocchi^1|2, R. Pastorino^1|2, G. Murante^1|2|3, S. Bergonzi^1|2|3, M. Capetta^1|2|3, F. Valeri^2|3, C. Dainese^2|3, A. Valpreda⁴, B. Bruno^1|3, A. Borchiellini^2|3 | ¹Department of Molecular Biotechnology and Health Sciences, University of Turin, Italy; ²Regional Centre for Thrombotic and Hemorrhagic Diseases, AOU Città della salute e della Scienza di Torino, Italy; ³Division of Hematology, AOU Città della Salute e della Scienza, University of Turin, Italy; ⁴Central Lab Baldi and Riberi, AOU Città della salute e della Scienza di Torino, Italy

  Francesca Bocchi

  14-10-2026

  https://doi.org/10.4081/btvb.2026.646

  22

  PDF: 12

• CO-23 | PERIOPERATIVE MANAGEMENT OF MILD-TO-MODERATE HEMOPHILIA: A COMPARATIVE STUDY OF EXTENDED HALF-LIFE VERSUS STANDARD HALF-LIFE CONCENTRATES ON CLINICAL OUTCOMES AND FACTOR CONSUMPTION M. Capetta^1|2|3, F. Valeri^1|2, C. Dainese^1|2, S. Bergonzi^1|2|3, G. Murante^1|2|3, A. Valpreda⁴, R. Pastorino^1|3, F. Bocchi^1|3, B. Bruno^2|3, A. Borchiellini^1|2 | ¹Regional Centre for Hemorrhagic and Thrombotic Diseases, AOU Città della Salute e della Scienza, Torino, Italy; ²Division of Hematology, AOU Città della Salute e della Scienza, University of Turin, Italy; ³Department of Molecular Biotechnology and Health Sciences, University of Turin, Italy; ⁴Central Laboratory Baldi and Riberi, AOU Città della Salute e della Scienza, University of Turin, Italy

  Matilde Capetta

  14-10-2026

  https://doi.org/10.4081/btvb.2026.633

  27

  PDF: 9

• CO16 | The predictive value of high-sensitivity C-reactive protein for assessing thrombosis risk in non-small cell lung cancer P. Gomez-Rosas^1,2, M. Marchetti^1,3, L. Russo¹, C.J. Tartari¹, S. Bolognini¹, C. Ticozzi¹, F. Schieppati¹, A. D’Alessio⁴, R. Labianca⁵, A. Falanga^1,3 All on behalf of the Hypercan Investigators | ¹Hospital Papa Giovanni XXIII, Bergamo, Italy; ²Cardiovascular Research Institute Maastricht, CARIM, Maastricht University, Maastricht, the Netherlands; ³School of Medicine and Surgery, University of Milan Bicocca, Italy; ⁴University Vita-Salute San Raffaele, Milan, Italy; ⁵Fondazione ARTET Onlus, Bergamo, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.220

  630

  PDF: 14
• 

  PO44 | PREDICTORS OF ONE-YEAR MORTALITY IN NEWLY DIAGNOSED METASTATIC BREAST CANCER: THE PROGNOSTIC ROLE OF HEMOSTATIC BIOMARKERS AND EARLY THROMBOEMBOLISM M. Marchetti^1|2|3, P. Gomez-Rosas^1|4|5, S. Bolognini¹, C. Ticozzi¹, D. Romeo¹, F. Schieppati^1|3, L. Barcella^1|3, F. Petrelli⁶, A. D'Alessio⁷, R. Labianca⁷, A. Falanga^1|2|3 | ¹Immunohematology and Transfusion Medicine, Hospital Papa Giovanni XXIII, Bergamo, Italy; ²School of Medicine and Surgery, University of Milan Bicocca, Milan, Italy; ³ERN EuroBloodNet; ⁴Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, The Netherlands; ⁵Hospital de Oncologia, Unidad Medica de Alta Especialidad (UMAE), Centro Medico Nacional Siglo XXI, Instituto Mexicano del Seguro Social (IMSS), Mexico City, Mexico; ⁶Oncology Unit, Hospital Treviglio-Caravaggio, Treviglio, Italy; ⁷Fondazione ARTET Onlus, Bergamo, Italy; *On behalf of the Hypercan Investigators

  ICTHIC 2026

  16-04-2026

  https://doi.org/10.4081/btvb.2026.538

  448

  PDF: 106

• CO-15 | HEMOPHILIA AND PHYSICAL ACTIVITY: A SURVEY ON THE CURRENT STATUS OF SPORTS ACCESSIBILITY IN THE ITALIAN POPULATION L. Laterza¹, M. Attanasi¹, C. Cassone², P. Giordano³, G. Lassandro³ | ¹University of Bari "Aldo Moro", Interdisciplinary of Medicine, Bari, Italy; ²Fedemo, Milano, Italy; ³Pediatric Haemophilia Center - AOUC Pol. Giovanni XXXIII, University of Bari "Aldo Moro", Italy

  Luisa Laterza

  14-10-2026

  https://doi.org/10.4081/btvb.2026.625

  69

  PDF: 11

• PO72 | Fondaparinux in patient with active tuberculosis T. Marrazzo¹, R. Parrella², A. Botta², A. Pontarelli², M.P. Ursi³, A. Karruli⁴, R. Albisinni⁵ | ¹UOC Medicina Interna e dei Trapianti, Ospedale Monaldi, Napoli, Italy; ²UOC Malattie Infettive ad Indirizzo Respiratorio, Ospedale Cotugno Azienda dei Colli, Napoli, Italy; ³UOC MECAU Ospedale CTO Azienda dei Colli, Napoli, Italy; ⁴Malattie Infettive e Tropicali, Ospedale di Tirana, Albania; ⁵UOC CCH Generale, Ospedale Monaldi Azienda dei Colli, Napoli, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.341

  627

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• CO-54 | DECREASED BONE MINERAL DENSITY IN HEMOPHILIA IS NOT CORRELATED WITH INCREASED RISK OF FRACTURES M.R. Fasulo¹, F. Carrone², G. Mazziotti^3|4, A. Colombo¹, C. Lodigiani¹, M.E. Mancuso^1|4 | ¹Center for Thrombosis and Hemorrhagic Diseases, IRCCS Humanitas Research Hospital, Rozzano, Milano, Italy; ²Endocrinology and Diabetology Unit, Humanitas Mater Domini, Castellanza, Varese, Italy; ³Endocrinology, Diabetology and Medical Andrology Unit, Metabolic Bone Diseases and Osteoporosis Section, IRCCS Humanitas Research Hospital, Rozzano, Milano, Italy; ⁴Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milano, Italy

  Maria Rosaria Fasulo

  14-10-2026

  https://doi.org/10.4081/btvb.2026.664

  21

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• CO-73 | WHEN BLEEDING MIMICS THROMBOSIS: DIAGNOSTIC DELAY AND THROMBOTIC COMPLICATIONS IN ACQUIRED HEMOPHILIA A R. Tomasello¹, M. Mattana¹, S. Raso¹, F. Schirò¹, P. Polidori², M.I. Di Lena³, F. La Gattuta⁴, M. Napolitano¹ | ¹Ematologia e malattie rare, PO Cervello di Palermo, Italy; ²Farmacia ospedaliera, PO Cervello di Palermo, Italy; ³Direzione medica, PO Cervello di Palermo, Italy; ⁴Radiologia interventistica, PO Villa Sofia di Palermo, Italy

  Riccardo Tomasello

  14-10-2026

  https://doi.org/10.4081/btvb.2026.683

  27

  PDF: 8

• CO-41 | COMPARISON OF COAGULATION AND CHROMOGENIC METHODS IN PHARMACOKINETICS WITH EXTENDED HALF-LIFE FACTOR VIII R. Pastorino^1|2, F. Bocchi^1|2, G. Murante^1|2|3, S. Bergonzi^1|2|3, M. Capetta^1|2|3, F. Valeri^2|3, C. Dainese^2|3, A. Valpreda⁴, B. Bruno^1|3, A. Borchiellini^2|3 | ¹Department of Molecular Biotechnology and Health Sciences, University of Turin, Italy; ²Regional Centre for Thrombotic and Hemorrhagic Diseases, AOU Città della salute e della Scienza di Torino, Italy; ³Division of Hematology, AOU Città della Salute e della Scienza, University of Turin, Italy; ⁴Central Lab Baldi and Riberi, AOU Città della salute e della Scienza di Torino, Italy

  Rebecca Pastorino

  14-10-2026

  https://doi.org/10.4081/btvb.2026.651

  21

  PDF: 10

• CO-28 | SYNERGISTIC EFFECT OF RECOMBINANT FACTOR INFUSION ON THROMBIN GENERATION IN HEMOPHILIA PATIENTS UNDER EMICIZUMAB OR CONCIZUMAB PROPHYLAXIS F. Bocchi^1|2, R. Pastorino^1|2, G. Murante^1|2|3, S. Bergonzi^1|2|3, M. Capetta^1|2|3, F. Valeri^2|3, C. Dainese^2|3, A. Valpreda⁴, B. Bruno^1|3, A. Borchiellini^2|3 | ¹Department of Molecular Biotechnology and Health Sciences, University of Turin, Italy; ²Regional Centre for Thrombotic and Hemorrhagic Diseases, AOU Città della salute e della Scienza di Torino, Italy; ³Division of Hematology, AOU Città della Salute e della Scienza, University of Turin, Italy; ⁴Central Lab Baldi and Riberi, AOU Città della salute e della Scienza di Torino, Italy

  Francesca Bocchi

  14-10-2026

  https://doi.org/10.4081/btvb.2026.638

  25

  PDF: 15

• CO-46 | MILD HEMOPHILIA A AND JOINT HEALTH IN REAL LIFE: IS THAT AN EMERGING ISSUE? A SINGLE CENTER EXPERIENCE G. Murante^1|2|3, F. Valeri^1|2, S. Bergonzi^1|2|3, M. Capetta^1|2|3, C. Dainese^1|2, A. Valpreda⁴, R. Pastorino^1|3, F. Bocchi^1|3, B. Bruno^2|3, A. Borchiellini^1|2 | ¹Regional Centre for Hemorrhagic and Thrombotic Diseases, AOU Città della Salute e della Scienza of Turin, Italy; ²Division of Hematology, AOU Città della Salute e della Scienza, University of Turin, Italy; ³Dep. of Molecular Biotechnology and Health Sciences, University of Turin, Italy; ⁴Central Lab. Baldi and Riberi, AOU Città della Salute e della Scienza of Turin, Italy

  Giovanni Murante

  14-10-2026

  https://doi.org/10.4081/btvb.2026.656

  18

  PDF: 10
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  PO21 | PSYCHOLOGICAL IMPACT OF CANCER-ASSOCIATED THROMBOSIS: DUAL BURDEN AND IMPLICATIONS FOR QUALITY OF LIFE AND INTEGRATED PATIENT-CENTERED CARE G. Gerotziafas^1|4, Y. Mitrou⁵, M. Marchetti⁶, P. Las Casa¹, A. Tafur⁷, V. Bitsadze³, J. Khizroeva³, D. Taizhanova⁸, D. Antic⁹, C. Frére¹⁰, A. Makatsariya³, L. Garderet^1|11, A. Escargueil¹, C. Ay¹², N. Lomatkin¹³, Z. Tazi-Mezalek¹⁴, M. Sassi¹⁵, M. Catalano^4|16, J. Gligorov^1|17, J. Caprini¹⁸, P. Van Dreden^1|19, J. Fareed², A. Falanga⁶ | ¹Sorbonne University, INSERM UMR_S_938, CRSA, Research Department "Cancer, Vessels, Biology and Therapeutics" (CaVITE), Research Group "Cancer-Angiogenesis-Thrombosis and Haemostasis," Thrombosis Center, University Institute of Cancerology (UIC), Saint Antoine University Hospital Assistance Publique Hôpitaux de Paris (AP-HP)Paris France; ²Center of Translational Research and Education, Department of Pathology and Laboratory Medicine, Loyola University Stritch School of Medicine, Maywood, Chicago, USA; ³Thrombosis Center, Department of Obstetrics, Gynecology and Perinatal Medicine, The I. M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia; ⁴VAS-European Independent Foundation in Angiology/Vascular Medicine Milan Italy; ⁵Department of Phylosophy, National and Kapodistrian University of Athens, Greece; ⁶Department of Immunohematology and Transfusion Medicine, Hospital Papa Giovanni XXIII, Bergamo, Italy. School of Medicine and Surgery, University of Milan Bicocca, Milan, Italy; ⁷Vascular Medicine, Endeavor Health, Evanston, IL, USA; Pritzker School of Medicine, University of Chicago, Chicago, IL 60637, USA; ⁸Department of Internal Diseases, Karaganda Medical University Non-Commercial Joint Stock Company, Karaganda, Kazakhstan; ⁹Clinic for Hematology, University Clinical Center of Serbia, Faculty of Medicine University of Belgrade Belgrade Serbia; ¹⁰Department of Hematology, Pitié-Salpêtrière Hospital, Assistance Publique-Hôpitaux de Paris, Sorbonne Université, INSERM UMRS-1166 Institute of Cardiometabolism and Nutrition, Paris, France; ¹¹Clinical Haematology Department, Sorbonne Université, Pitié-Salpêtrière Hospital, APHP, Paris; ¹²Department of Internal Medicine I, Clinical Division of Haematology and Haemostaseology, Medical University of Vienna, Vienna, Austria; ¹³Cardiology Division, Central Clinical Hospital of Presidential Administration, Moscow, Russia; ¹⁴Department of Internal Medicine, Hématologie Clinique, Centre Hospitalo-Universitaire Ibn Sina, Université Mohammed V de Rabat, Rabat, Morocco; ¹⁵Hematology Laboratory of Maternity and Neonatal Center of Monastir, Faculty of Pharmacy of Monastir, Monastir, Tunisia; ¹⁶Inter-University Research Center on Vascular Diseases, University of Milan-L Sacco Hospital, Milan, Italy; ¹⁷Medical Oncology Department, Tenon Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Sorbonne University, Paris, France; ¹⁸Vascular Surgery, Pritzker School of Medicine at the University of Chicago, Chicago, USA; ¹⁹Clinical Research, Diagnostica Stago, Gennevilliers, France

  ICTHIC 2026

  16-04-2026

  https://doi.org/10.4081/btvb.2026.516

  444

  PDF: 94

• CO-39 | MYELOID CELL FUNCTION AND CYTOKINE PROFILES IN PEDIATRIC HEMOPHILIA A: INSIGHTS FROM FACTOR VIII AND EMICIZUMAB PROPHYLAXIS T. Martini¹, A. Cottonaro², S. Akula², B. Pollio¹, I. Ricca³, J. Agnelli Giacchello⁴, P. Sciancalepore⁴, R. Santi⁴, A. Follenzi^2|4, S. Merlin² | ¹Haemophilia Centre, Immune-Haematology and Transfusion Medicine, University Hospital “Città della Salute e della Scienza”, Torino, Italy; ²Department of Health Sciences, Università del Piemonte Orientale, Novara, Italy; ³Transfusion Medicine, Ivrea Hospital, Ivrea, Italy; ⁴Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo, Alessandria, Italy

  Tiziano Martini

  14-10-2026

  https://doi.org/10.4081/btvb.2026.649

  31

  PDF: 10

• CO37 | Assessment of clotting factor activity and sterility in thawed fresh frozen plasma supplied to helicopter emergency medical services for prehospital transfusion D. Romeo¹, M. Marchetti^1,2, M. Testa¹, A. Motta¹, P. Gomez-Rosas¹, G. Ravasio¹, F. Daminelli³, L. Barcella¹, A. Falanga^1,2 | ¹Immunohematology and Transfusion Medicine Department, Hospital Papa Giovanni XXIII, Bergamo; ²School of Medicine and Surgery, University Milano Bicocca, Milan; ³Anesthesia and Resuscitation Department, Hospital Papa Giovanni XXIII, Bergamo, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.244

  675

  PDF: 18

• BEST-08 | PERIOPERATIVE MANAGEMENT OF CHILDREN WITH MILD FACTOR VII DEFICIENCY UNDERGOING SURGERY: A RETROSPECTIVE COHORT STUDY B. Borsellino¹, T. Martini¹, I. Ricca², B. Pollio¹ | ¹Haemophilia Centre, Immune-Haematology and Transfusion Medicine, University Hospital “Città della Salute e della Scienza”, Torino, Italy; ²Transfusion Medicine, Ivrea Hospital, Ivrea, Italy

  Tiziano Martini

  14-10-2026

  https://doi.org/10.4081/btvb.2026.608

  73

  PDF: 9
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  PO16 | EPIDEMIOLOGY, CLINICAL CHARACTERISTICS, AND OUTCOMES OF PROVOKED AND UNPROVOKED PULMONARY EMBOLISM IN A MULTICULTURAL ISRAELI POPULATION R. Farah¹, N.L. Bragazzi^2|3|4, H.İ. Ceylan⁵, Ł. Szarpak^6|7|8|9, W. Mahajni¹, N. Ashqar¹, A. M. Fioretti¹⁰, R. Khamisy-Farah¹¹ | ¹Internal Medicine B Department, Ziv Medical Center, Azrieli Faculty of Medicine, Bar-Ilan University, Galilee, Safed, Israel; ²Laboratory for Industrial and Applied Mathematics, Department of Mathematics and Statistics, York University, Toronto, Canada; ³Postgraduate School of Public Health, Department of Health Sciences, University of Genoa, Italy; ⁴UNESCO Chair, Health Anthropology, Biosphere and Healing Systems, University of Genoa, Italy; ⁵Physical Education and Sports Teaching Department, Faculty of Sports Sciences, Atatürk University, Erzurum, Turkey; ⁶Department of Clinical Research and Development, LUXMED Group, Warsaw, Poland; ⁷Institute of Medical Science, Collegium Medicum, The John Paul II Catholic University of Lublin, Lublin, Poland; ⁸The World Academic Council of Emergency Medicine, Sarasota, FL, USA; ⁹Henry JN Taub Department of Emergency Medicine, Baylor College of Medicine, Houston, TX, USA; ¹⁰Cardio-Oncology Unit, IRCCS Istituto Tumori “Giovanni Paolo II”, Bari, Italy; ¹¹Clalit Health Service, Azrieli Faculty of Medicine, Bar-Ilan University, Galilee, Safed, Israel

  ICTHIC 2026

  16-04-2026

  https://doi.org/10.4081/btvb.2026.511

  430

  PDF: 108

• CO-50 | LEFT ATRIAL APPENDAGE OCCLUSION IN PATIENTS WITH ATRIAL FIBRILLATION AND BLEEDING DISORDERS: A SINGLE-CENTER EXPERIENCE B.M. Roccon¹, M.I. Tassoni¹, G. Quintavalle¹, G. Benatti², F. Gurgoglione², R. Rossi³, C. Cattabiani³, L. Vignali², A. Tagliaferri¹, A. Coppola¹ | ¹SSD Centro Hub Emofilia e Malattie Emorragiche Congenite, Azienda Ospedaliero-Universitaria di Parma, Italy; ²SSD Cardiologia Interventistica, Azienda Ospedaliero-Universitaria di Parma, Italy; ³Laboratorio di Coagulazione, UOC Patologia Clinica, Azienda Ospedaliero-Universitaria di Parma, Italy

  Antonio Coppola

  14-10-2026

  https://doi.org/10.4081/btvb.2026.660

  23

  PDF: 11

• CO44 | First interlaboratory validation workshop of immunofluorescence microscopy on the peripheral blood smear for recognizing patients with inherited platelet disorders C. Zaninetti¹, L. Bury², V. Bozzi³, A. Zamora-Cánovas⁴, K. Althaus⁵, G. Uzun⁵, S. Brown⁶, A. Norman⁶, D. Faille⁷, A. Stepanian⁸, C. Freyer¹, L. Kager⁹, T. Bakchoul⁵, A. Pecci³, P. Gresele², T. Thiele¹, J. Rivera⁴, A. Greinacher¹ | ¹Institut für Immunologie und Transfusionsmedizin, Universitätsmedizin Greifswald, Germany; ²Department of Medicine, Section of Internal and Cardiovascular Medicine, University of Perugia, Italy; ³Department of Internal Medicine, University of Pavia, Italy; General Medicine 1, IRCCS Policlinico San Matteo Foundation, Pavia, Italy; ⁴Servicio de Hematología, Hospital Universitario Morales Meseguer, Centro Regional de Hemodonacio´n, Universidad de Murcia, Spain; ⁵Institute for Clinical and Experimental Transfusion Medicine, University Hospital of Tuebingen, Germany; Center for Clinical Transfusion Medicine, Tuebingen, Germany; ⁶Centre for Children’s Health and Research CCHR, South Brisbane, Australia; ⁷Laboratoire d’Hématologie, Assistance Publique Hôpitaux de Paris, Hôpital Bichat-Claude-Bernard, Paris, France; ⁸AP-HP, Service d’Hématologie Biologique, Hôpital Lariboisière, Paris Cité University, Paris, France; ⁹St. Anna Kinderspital, Universitätsklinik für Kinder- und Jugendheilkunde der Medizinischen Universität Wien, Austria

  22-10-2025

  https://doi.org/10.4081/btvb.2025.250

  587

  PDF: 20

• CS04 | Association between elevated plasma levels of tissue plasminogen activator and occult cancer risk: a nested case-cohort analysis in 10,294 healthy subjects S. Bolognini^1,2, C. Ticozzi¹, P. Gomez-Rosas^1,3, L. Russo^1,2, Cj. Tartari^1,2, F. Schieppati^1,2, G. Sampietro⁴, L. Barcella¹, M. Marchetti^1,2, A. Falanga^1,2 | ¹Immunohematology and Transfusion Medicine, Hospital Papa Giovanni XXIII, Bergamo, Italy; ²School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy; ³Maastricht University Medical Center, Cardiovascular Research Institute Maastricht, The Netherlands; ⁴Unit of Epidemiology and Statistics, ATS Bergamo, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.201

  686

  PDF: 29

• CO-56 | EVALUATING AN AI MODEL’S HEMATOLOGY CONSULTATION PERFORMANCE FOR HOSPITALIZED PATIENTS WITH BLEEDING DISORDERS G. Sottilotta¹, F. Misiti², G. Praticò¹, D. Megalizzi¹, F. Luise³ | ¹UOSD Microcitemie - Emostasi e Trombosi. Grande Ospedale Metropolitano di Reggio Calabria, Italy; ²Associazione Emofilici di Reggio Calabria, Italy; ³Laboratorio Analisi. Grande Ospedale Metropolitano di Reggio Calabria, Italy

  Gianluca Sottilotta

  14-10-2026

  https://doi.org/10.4081/btvb.2026.666

  20

  PDF: 13

• CO-62 | ACCESS TO ULTRA-LONG HALF-LIFE FACTOR VIII AS THE DEFINITIVE MOTIVATION FOR IMMUNE TOLERANCE INDUCTION IN THE ERA OF NON-REPLACEMENT THERAPIES B. Borsellino¹, T. Martini¹, I. Ricca², C. Linari³, B. Pollio¹ | ¹Paediatric Haemophilia Centre, Immune-Haematology and Transfusion Medicine, University Hospital "Città della Salute e della Scienza", Torino, Italy; ²Transfusion Medicine, Ivrea Hospital, Ivrea, Italy; ³Department of Laboratory Medicine, Azienda Ospedaliera Universitaria Città della Salute e della Scienza, Turin, Italy

  Beatrice Borsellino

  14-10-2026

  https://doi.org/10.4081/btvb.2026.672

  24

  PDF: 9

• CO-81 | DIGITAL NETWORKING FOR ACQUIRED HEMOPHILIA A: A REGION-WIDE CARE PATHWAY FROM DIAGNOSIS TO FOLLOW-UP M. Mattana¹, M.F. Mansueto², S. Raso¹, S. Siragusa^2|3, R. Tomasello¹, M. Napolitano^1|3 | ¹A.O.O.R. Villa Sofia Cervello P.O. Cervello-UOC di Ematologia per le Malattie Rare del Sangue e degli Organi Ematopoietici, Palermo, Italy; ²UOC Ematologia Policlinico P.Giaccone Palermo, Italy; ³Dipartimento Promozione della Salute, Materno-Infantile, di Medicina Interna e Specialistica di Eccellenza(PROMISE), Università degli studi di Palermo, Italy

  Marta Mattana

  14-10-2026

  https://doi.org/10.4081/btvb.2026.691

  21

  PDF: 8

• CO-49 | JOINT STATUS EVALUATION BY ULTRASOUND AND FUNCTIONAL ASSESSMENT IN PERSONS WITH NON SEVERE HEMOPHILIA ON PROPHYLAXIS WITH FOCUS ON THOSE WITH 5-YR FOLLOW UP G. Quintavalle¹, M.I. Tassoni¹, B.M. Roccon¹, G.F. Rivolta¹, C. Costantino², R.M. Polo³, A. Matichecchia¹, A. Tagliaferri¹, A. Coppola¹ | ¹SSD Centro Hub Emofilia e Malattie Emorragiche Congenite, Az. Ospedaliero-Universitaria di Parma, Italy; ²SSD Riabilitazione Ambulatoriale e Ortogeriatrica, Az. Ospedaliero-Universitaria di Parma, Italy; ³Clinica Ortopedica, Az. Ospedaliero-Universitaria di Parma, Italy

  Gabriele Quintavalle

  14-10-2026

  https://doi.org/10.4081/btvb.2026.659

  20

  PDF: 10

• CO-17 | EMBODIED SELF-MANAGEMENT IN HEMOPHILIA: PSYCHOSOMATIC EFFECTS OF A SUPERVISED PHYSICAL ACTIVITY PROGRAM F. Valeri¹, M. Miniotti², M.G. Bailon², C. Dainese¹, B. Bruno³, P. Leombruni², A. Borchiellini¹ | ¹Regional Centre for Haemorrhagic and Thrombotic Disease, Hematology Division, AOU Città della Salute e della Scienza, Torino, Italy; ²Departement of Neurosciences Rita Levi Montalcini, University of Turin, Italy; ³Division of Hematology, AOU Città della Salute e della Scienza, Department of Molecular Biotechnology and Health sciences, University of Turin, Italy

  Federica Valeri

  14-10-2026

  https://doi.org/10.4081/btvb.2026.627

  19

  PDF: 6

• CO-03 | BEYOND CONVENTIONAL TESTING: NANOPORE LONG-READ SEQUENCING FOR RECURRENT F8 INVERSIONS IN HEMOPHILIA A A. Taiani^1|2, F. Riccardi¹, L. Cozzuto⁴, A. Delgado⁴, S. Busciglio^1|2, G. Quintavalle¹, A. Matichecchia¹, I. Tassoni¹, B.M. Roccon¹, I. R. Cannizzaro², A. Luberto², J. Ponomarenko⁴, A. Percesepe³, V. Barili², A. Coppola¹ | ¹Regional Hub Center for Hemophilia and Congenital Bleeding Disorders, University Hospital of Parma, Italy; ²Medical Genetics, Department of Medicine and Surgery, University of Parma, Italy; ³Medical Genetics, University Hospital of Parma, Italy; ⁴Centre Genomic Regulation, CRG, Barcelona, Spain

  Antonietta Taiani

  14-10-2026

  https://doi.org/10.4081/btvb.2026.613

  66

  PDF: 10
• 

  Development of a shared decision-making tool for gene therapy in hemophilia A in Italy

  Giovanni Di Minno, Sarah Bigi, Serena Barello, Enrico Ferri Grazzi, Marco Follino, Maria Francesca Mansueto, Mariasanta Napolitano, Rita Carlotta Santoro, Giancarlo Castaman

  22-06-2026

  https://doi.org/10.4081/btvb.2026.426

  919

  PDF: 131

  SUPPLEMENTARY MATERIAL: 78

• PO12 | Characterisation and real word clinical data of HEM006, a newly formulated intranasal spray desmopressin (DDAVP) to address a global treatment gap G. De Giorgi¹, A. Gringeri², R. Franceschini¹, A. Koganti³ | ¹Hemorare Srl, Italy; ²Fondazione Charta, Milan, Italy; ³Quenya LLC, USA

  22-10-2025

  https://doi.org/10.4081/btvb.2025.274

  568

  PDF: 12
• 

  Executive summary of the SISET position paper on the management of antithrombotic therapy in left ventricular thrombus

  Emanuele Valeriani, Arianna Pannunzio, Danilo Menichelli, Domenico Prisco, Walter Ageno, Daniele Pastori, Pasquale Pignatelli

  16-12-2025

  https://doi.org/10.4081/btvb.2025.401

  456

  PDF: 132

  HTML: 110

• CO-08 | IMPLEMENTING A HUB-AND-SPOKE MODEL FOR HEMOPHILIA DIAGNOSIS AND CARE IN BURKINA FASO THROUGH TRAINING OF “HEALTH ASSISTANTS” C. Gorio¹, E. Kafando², A. Buzzi³ | ¹Oncohematology Unit ASST Spedali Civili Brescia, Italy; ²Centre Hospitalier Universitaire Charles de Gaulle, Italy; ³Fondazione Paracelso ETS, Milano, Italy

  Chiara Gorio

  14-10-2026

  https://doi.org/10.4081/btvb.2026.618

  63

  PDF: 9
• 

  PO43 | ELEVATED CIRCULATING TISSUE PLASMINOGEN ACTIVATOR LEVELS PREDICT GASTROINTESTINAL AND BREAST CANCER RISK: A PROSPECTIVE NESTED CASE-COHORT STUDY S. Bolognini^1|2, C. Ticozzi¹, P. Gomez-Rosas^1|3, F. Schieppati^1|2, G. Sampietro⁴, L. Barcella¹, M. Marchetti^1|2, A. Falanga^1|2 | ¹Immunohematology and Transfusion Medicine, Hospital Papa Giovanni XXIII, Bergamo, Italy; ²School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy; ³Maastricht University Medical Center, Cardiovascular Research Institute Maastricht (CARIM), Maastricht, The Netherlands; ⁴Unit of Epidemiology and Statistics, ATS Bergamo, Italy

  ICTHIC 2026

  16-04-2026

  https://doi.org/10.4081/btvb.2026.537

  454

  PDF: 113
• 

  Diagnosis and management of abnormal uterine bleeding in adolescence An expert Consensus Statement of SIGO (Italian Society of Gynecology and Obstetrics) and SISET (Italian Society for the Study of Hemostasis and Thrombosis)

  Roberto Mario Santi, Annamaria Fulghesu, Ezio Zanon, Erica De Candia, Elvira Grandone, Giancarlo Di Renzo, Claudia Succu, Valentina Tosto, Vincenzina Bruni, Paolo Gresele

  08-05-2024

  https://doi.org/10.4081/btvb.2024.106

  2838

  PDF: 728

• PO52 | Comprehensive assessment of variables affecting spontaneous platelet aggregation C. Ghali¹, A. Fioretti¹, M. Scavone¹, E. Bossi¹, B. Clerici¹, S. Birocchi¹, E. Popov², M. Centola³, G.M. Podda¹, M. Cattaneo⁴ | ¹Divisione di Medicina Generale II, ASST Santi Paolo e Carlo, DISS, Università degli Studi di Milano, Italy; ²National Medical Research Center of Cardiology, Ministry of Health of the Russian Federation, Moscow; ³Division of Cardiology, Pio XI Hospital, ASST Brianza, Desio, Italy; ⁴Fondazione Arianna Anticoagulazione, Bologna, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.321

  672

  PDF: 20

• CO14 | Inflammation and fibrinolysis biomarkers as predictors of cancer risk in healthy subjects: results from the hypercan study C. Ticozzi¹, S. Bolognini^1,2, P. Gomez-Rosas^1,3, L. Russo^1,2, Cj. Tartari^1,2, F. Schieppati^1,2, G. Sampietro⁴, L. Barcella¹, M. Marchetti^1,2, A. Falanga^1,2 | ¹Immunohematology and Transfusion Medicine, Hospital Papa Giovanni XXIII, Bergamo, Italy; ²School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy; ³Maastricht University Medical Center, Cardiovascular Research Institute Maastricht, Maastricht, The Netherlands; ⁴Unit of Epidemiology and Statistics, ATS Bergamo, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.218

  657

  PDF: 18
• 

  PO42 | DIFFERENTIAL EXPRESSION OF HEMOSTATIC BIOMARKERS ACROSS CANCER TYPE AND DISEASE STAGE: A PROSPECTIVE ANALYSIS OF 4,292 PATIENTS FROM THE HYPERCAN STUDY P. Gómez-Rosas^1|2|, D. Romeo¹, S. Bolognini¹, C. Ticozzi¹, F. Schieppati¹, A. D’Alessio⁴, R. Labianca⁴, A. Falanga^1|5|6, M. Marchetti^1|5|6 | ¹Hospital Papa Giovanni XXIII, Bergamo, Italy; ²Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, the Netherlands; ³Hospital de Oncologia, Unidad Medica de Alta Especialidad (UMAE), Centro Medico Nacional Siglo XXI, Instituto Mexicano del Seguro Social (IMSS), Mexico City, Mexico; ⁴Fondazione ARTET Onlus, Bergamo, Italy; ⁵ERN EuroBloodNet; ⁶School of Medicine and Surgery, University of Milan Bicocca, Italy; *On Behalf Of The Hypercan Investigators

  ICTHIC 2026

  16-04-2026

  https://doi.org/10.4081/btvb.2026.536

  487

  PDF: 110

• BEST-10 | CHANGES IN HYPERTROPHIC SYNOVIUM STATUS IN ADULT PATIENTS WITH SEVERE HEMOPHILIA A RECEIVING EMICIZUMAB PROPHYLAXIS: THE RESOLVE STUDY I.L. Calcaterra¹, M. Di Minno¹, E. Baldacci², G. D’Errico¹, C. Santoro², A. Strangio³, S. Sorella², M. Leotta³, R.C. Santoro³ | ¹Department of Clinical Medicine and Surgery, Federico II University, Napoli, Italy; ²Haematology, University Hospital Policlinico Umberto I, Roma, Italy; ³Hemostasis and Thrombosis Centre, Azienda Ospedaliero Universitaria Renato Dulbecco, Catanzaro, Italy

  Ilenia Lorenza Calcaterra

  14-10-2026

  https://doi.org/10.4081/btvb.2026.610

  65

  PDF: 11
• 

  Management of anticoagulation in atrial fibrillation patients in Italy: insight from the Atrial Fibrillation-Survey on Anticoagulated Patients Register (AF-START)

  Daniela Poli, Walter Ageno, Emilia Antonucci, Salvatore Bradamante, Eugenio Bucherini, Paolo Chiarugi, Antonio Chistolini, Benilde Cosmi, Anna Falanga, Antonio Insana, Domenico Lione, Rosa Maria Lombardi, Giuseppe Malcangi, Rossella Marcucci, Giuliana Martini, Lucilla Masciocco, Carmelo Paparo, Daniele Pastori, Simona Pedrini, Vittorio Pengo, Pasquale Pignatelli, Andrea Toma, Sophie Testa, Gualtiero Palareti

  27-06-2023

  https://doi.org/10.4081/btvb.2023.84

  2150

  PDF: 641

  Supplementary File: 286
• 

  PO17 | PREDICTIVE VALUE OF INFLAMMATORY AND ENDOTHELIAL BIOMARKERS FOR CANCER RISK IN HEALTHY INDIVIDUALS: EVIDENCE FROM THE HYPERCAN STUDY C. Ticozzi¹, S. Bolognini^1|2, P. Gomez-Rosas^1|3, F. Schieppati^1|2, G. Sampietro⁴, L. Barcella¹, M. Marchetti^1|2, A. Falanga^1|2 | ¹Immunohematology and Transfusion Medicine, Hospital Papa Giovanni XXIII, Bergamo, Italy; ²School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy; ³Maastricht University Medical Center, Cardiovascular Research Institute Maastricht (CARIM), Maastricht, The Netherlands; ⁴Unit of Epidemiology and Statistics, ATS Bergamo, Italy

  ICTHIC 2026

  16-04-2026

  https://doi.org/10.4081/btvb.2026.512

  429

  PDF: 97
• 

  PO69 | INCIDENTAL CANCER DETECTED DURING EMERGENCY DIAGNOSTIC WORK-UP FOR ACUTE PULMONARY EMBOLISM: A RETROSPECTIVE COHORT STUDY L. Mocerino¹, A. Casoria², S. Mangiacapra², M. Amitrano², V. Bassi³, A. Tufano¹ | ¹Department of Clinical Medicine and Surgery. Federico II University of Naples, Italy; ²Internal Medicine Unit, Moscati Hospital, Avellino, Italy; ³U.O.C. di Medicina Generale e Lungodegenza, San Giovanni Bosco Hospital, ASL; Na1 Centro, Naples, Italy

  ICTHIC 2026

  16-04-2026

  https://doi.org/10.4081/btvb.2026.558

  445

  PDF: 114

• CO-38 | CALIBRATION OF HUMAN COAGULATION FACTOR VIII IN NOVEL QUALITY CONTROL MATERIALS: A COLLABORATIVE STUDY G. Gullifa¹, A. Carocci¹, C. Albertini^1|2, L. Luchetti¹, M.T. Pasquino¹, M. Simeoni¹, L. Mandarino¹, C. Adriano^1|3, R. Risoluti³, S. Massimi¹ | ¹Centro Nazionale per il Controllo e la Valutazione dei Farmaci, Istituto Superiore di Sanità, Roma, Italy; ²Centro Nazionale Sangue, Istituto Superiore di Sanità, Roma, Italy; ³Sapienza Università di Roma, Italy

  Giuseppina Gullifa

  14-10-2026

  https://doi.org/10.4081/btvb.2026.648

  20

  PDF: 10

• CO-05 | IN SILICO ANALYSIS THROUGH A NEWLY GENERATED FACTOR VIII MODEL SUPPORTS TOLERANCE OF B DOMAIN TO MULTIPLE AMINO ACID SUBSTITUTIONS LIMITING THE LOCAL IMPACT OF MISSENSE VARIANTS A. Branchini¹, M.F. Testa¹, M. Pinotti¹, R. De Cristofaro^2|3 | ¹Department of Life Sciences and Biotechnology, University of Ferrara, Italy; ²Department of Translational Medicine and Surgery, Catholic University of the Sacred Heart, Roma, Italy; ³Center for Hemorrhagic and Thrombotic Diseases, Foundation University Hospital “A. Gemelli” IRCCS, Roma, Italy

  Alessio Branchini

  14-10-2026

  https://doi.org/10.4081/btvb.2026.615

  62

  PDF: 10

• PO02 | Pregnancy and delivery in women with hemophilia and carriers are still challenging: a ten years analysis from The Italian Association of Hemophilia Centers (AICE) M. Napolitano¹, M. Mattana², C. Cammarata¹, M. Leotta³, S. Linari⁴, M.E. Mancuso⁵, G. F. Rivolta⁶, C. Santoro⁷, L. Valdrè⁸, R.C. Santoro³, S. Siragusa¹ | ¹Department of Health Promotion, Mother and Child Care, Internal Medicine and Med, Palermo; University of Palermo, Italy; ²Department of Precision Medicine in Medical, Surgical and Critical Care “Me. Pre. Cc”, University of Palermo; ³Hemostasis and Thrombosis Unit, Azienda Ospedaliera Universitaria Dulbecco, Catanzaro; ⁴Center for Bleeding Disorders, Careggi University Hospital, Firenze; ⁵Center for Thrombosis and Hemorrhagic Diseases, IRCCS Humanitas Research Hospital, Rozzano, Milan; ⁶Regional Reference Center for the Treatment of Congenital Hemorrhagic Diseases, Parma University Hospital, Parma; ⁷Hematology, University Hospital Policlinico Umberto I, Roma; ⁸Inherited Bleeding Disorders Unit, IRCCS AOUBO, Bologna, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.312

  685

  PDF: 19

• PO49 | Use of emicizumab in two patients with acquired hemophilia A: a new therapeutic approach S. Sorella, J. Micozzi, E. Baldacci, M. Biglietto, R. Mormile, A. Chistolini, R. Ciciani, L. Torrieri, N. Zhdanovskaya, M. Lorenzon, A. Delli Paoli, S. Ligia, C. Santoro | Hematology, Department of Translational and Precision Medicine, Policlinico Umberto I, Sapienza University of Roma, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.318

  656

  PDF: 23

• CO-63 | ACQUIRED VON WILLEBRAND SYNDROME IN AN ELDERLY PATIENT WITH EARLY-STAGE B-CLL A. Casson¹, I. Ricca¹, A. Barchieri¹, G. Guido¹, P. Ocello¹, M. Tucciarone¹, S. Prestigio², A. Alfano², G. Delios¹ | ¹Centro Malattie Trombotiche ed Emorragiche - SC Servizio Trasfusionale ASL TO4, Ivrea, Italy; ²SC Laboratorio Analisi ASL TO4, Ivrea, Italy

  Andrea Casson

  14-10-2026

  https://doi.org/10.4081/btvb.2026.673

  19

  PDF: 13

• CO-18 | PSYCHOMETRIC ASSESSMENT OF PATIENT REPORTED EXPERIENCES WITH ARTIFICIAL INTELLIGENCE TOOLS IN HEMOPHILIA CARE G. Sottilotta ^1|2 , G. Praticò ¹ , D. Megalizzi ¹ , M. Hart ² , C. Komar ² , F. Luise ³ | ¹ UOSD Centro Microcitemie - Servizio Emostasi e Trombosi. Grande Ospedale Metropolitano di Reggio Calabria, Italy; ² Save One Life Inc., USA; ³ Laboratorio Analisi. Grande Ospedale Metropolitano di Reggio Calabria, Italy

  Gianluca Sottilotta

  14-10-2026

  https://doi.org/10.4081/btvb.2026.628

  23

  PDF: 8

• CO-69 | IN VITRO CORRECTION OF SEVERE FACTOR V DEFICIENCY USING A NOVEL PLASMA-DERIVED FACTOR V CONCENTRATE: A WHOLE BLOOD THROMBIN GENERATION STUDY C. Bulato¹, E. Campello¹, L. Spiezia¹, B. Serena¹, S. Toffanin¹, C. Simion¹, A. Caricasole², M. Sotgiu², A. Salvatore², F. Pierantoni², T.M. Hackeng^3|4, H.M.H. Spronk^3|4, P. Simioni¹ | ¹First Chair of Internal Medicine, Thrombotic and Haemorrhagic Diseases Unit and Haemophilia Centre, Department of Medicine, Padova University Hospital, Padova, Italy; ²Kedrion SpA, Barga Lucca, Italy; ³Coagulation Profile B.V., Maastricht, Netherland; ⁴Department of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, Netherland

  Cristiana Bulato

  14-10-2026

  https://doi.org/10.4081/btvb.2026.679

  22

  PDF: 8
• 

  PO27 | URINE QUALITATIVE ASSESSMENT OF DIRECT ORAL ANTICOAGULANTS IN ROUTINE CLINICAL PRACTICE F. Schieppati^1|2, P. Gomez-Rosas^1|3, C. Ambaglio¹, V. Brusegan¹, O.C. Cretu¹, E. Galimberti¹, F. Zunino¹, L. Barcella¹, J. Harenberg^4|5, A. Falanga^1|2, M. Marchetti^1|2 | ¹Immunohematology and Transfusion Medicine, Hospital Papa Giovanni XXIII, Bergamo, Italy; ²School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy; ³Maastricht University Medical Center, Cardiovascular Research Institute Maastricht, Maastricht, The Netherlands; ⁴Ruprecht Karls University of Heidelberg, Heidelberg, Germany; ⁵DOASENSE GmbH, Heidelberg, Germany

  ICTHIC 2026

  16-04-2026

  https://doi.org/10.4081/btvb.2026.522

  428

  PDF: 96

• PO80 | Heparin-induced thrombocytopenia: a monocentric experience with danaparoid L. D’Innocenzo, S. Sorrentino, M. De Siati, A. Ferretti, E. De Candia | Unit of Haemostasis and Thrombosis Diseases, Fondazione Policlinico Universitario A. Gemelli, IRCCS, Roma, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.349

  691

  PDF: 12

• CO-30 | AL AMYLOIDOSIS IN A PATIENT WITH SEVERE HEMOPHILIA A AND INHIBITORS WHO HAD A MONOZYGOTIC TWIN: SAME GENES, DIFFERENT OUTCOMES M. Biglietto^1|2, S. Sorella¹, S. Ligia¹, C. Andriola¹, R. Mormile¹, E. Baldacci¹, A. Chistolini¹, C. Santoro¹ | ¹Hematology, Department of Translational and Precision Medicine, Sapienza University of Rome, Italy; ²Department of Molecular Biology, Sapienza University of Rome, Italy

  Mario Biglietto

  14-10-2026

  https://doi.org/10.4081/btvb.2026.640

  29

  PDF: 12
• 

  PO12 | IMPACT OF INHERITED THROMBOPHILIA ON CANCER-ASSOCIATED THROMBOSIS: A SYSTEMATIC REVIEW AND META-ANALYSIS E. Campello¹, G. Furlan¹, A. Boccatonda², A. Napolitano¹, C. Simion¹, P. Simioni¹ | ¹Internal Medicine 1 and Thrombotic and Hemorrhagic Diseases Unit, Department of Medicine, University of Padova, Italy; ²Diagnostic and Therapeutic Interventional Ultrasound Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Policlinico Sant'Orsola-Malpighi, Bologna, Italy

  ICTHIC 2026

  16-04-2026

  https://doi.org/10.4081/btvb.2026.508

  461

  PDF: 105
• 

  PO26 | OUTCOMES OF DIRECT ORAL ANTICOAGULANTS IN UNUSUAL-SITE THROMBOSIS: IMPACT OF ACTIVE CANCER S. Guglielmo¹, M. Lovisotto¹, L. Scarano¹, E. De Bon², S. Barbar² | ¹Internal Medicine, Department of Medicine, Azienda Ulss 6 Euganea, Cittadella (PD), Italy; ²Thrombotic and Hemorrhagic Disorders Unit, Department of Medicine, Azienda Ulss 6 Euganea, Cittadella (PD), Italy

  ICTHIC 2026

  16-04-2026

  https://doi.org/10.4081/btvb.2026.521

  499

  PDF: 109

• CO-42 | LONGITUDINAL THROMBIN GENERATION PROFILING IN A PATIENT WITH SEVERE HEMOPHILIA A DURING ANTITHROMBIN-LOWERING THERAPY, CANCER, AND MAJOR SURGERY C. Simion^1|2, C. Bulato¹, E. Campello^1|2, E. Zanon^1|2, B. Serena¹, S. Toffanin¹, P. Simioni^1|2 | ¹First Chair of Internal Medicine and Thrombotic and Haemorrhagic Diseases Unit, Department of Medicine, Padova University Hospital, Italy; ²Hemophilia Center, Padova University Hospital, Italy

  Chiara Simion

  14-10-2026

  https://doi.org/10.4081/btvb.2026.652

  21

  PDF: 8

• CO-09 | THE POSSIBLE ROLE OF THE PSYCHOLOGIST IN THE MANAGEMENT OF PATIENTS WITH CONGENITAL BLEEDING DISORDERS: THE EXPERIENCE OF A SINGLE HEMOPHILIA CENTER D. Meneghini¹, E. Tosi¹, B. Pernice², L. Del Piccolo², M. Bodini¹, A.C. Giuffrida¹ | ¹Transfusion Medicine Dep., Integrated University Hospital, Verona, Italy; ²Dep. of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Italy

  Marco Bodini

  14-10-2026

  https://doi.org/10.4081/btvb.2026.619

  65

  PDF: 7
• 

  PO08 | NEXT-GENERATION THROMBOLYTICS: ENGINEERING STREPTOKINASE FOR ENHANCED ACTIVITY AND REDUCED IMMUNOGENICITY M. Kanwal^1|2 | ¹Consiglio Nazionale delle Ricerche, Naples, Italy; ²Department of Environmental, Biological and Chemical Sciences and Technologies, University of Campania "Luigi Vanvitelli", Italy

  ICTHIC 2026

  16-04-2026

  https://doi.org/10.4081/btvb.2026.504

  487

  PDF: 82

• PO40 | Management of paediatric patients affected by mild factor VII deficiency undergoing surgery B. Borsellino^1,2, B. Pollio¹, I. Ricca¹, R. Albiani¹, T. Martini¹ | ¹Haemophilia Centre, Immune-Haematology and Transfusion Medicine, University Hospital “Città della Salute e della Scienza”, Turin; ²Department of Biomedicine and Prevention, PhD in Immunology, Molecular Medicine and Applied Biotechnology, University of Roma Tor Vergata, Roma, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.303

  562

  PDF: 12
• 

  Welcome to the 12^th International Conference on Thrombosis and Hemostasis Issues in Cancer! Proceedings

  Anna Falanga, Benjamin Brenner, Alok A. Khorana

  16-05-2024

  https://doi.org/10.4081/btvb.2024.138

  1718

  PDF: 555

• CO-80 | EMICIZUMAB PLASMA CONCENTRATIONS AND CLINICAL OUTCOMES IN ACQUIRED HEMOPHILIA A: A REAL-WORLD SINGLE-CENTER EXPERIENCE C. Simion^1|2, E. Zanon^1|2, C. Bulato¹, B. Stocco^1|2, F. Righetto¹, F. Sartorello¹, P. Simioni^1|2 | ¹First Chair of Internal Medicine and Thrombotic and Haemorrhagic Diseases Unit, Department of Medicine, Padova University Hospital, Italy; ²Hemophilia Center, Padova University Hospital, Italy

  Chiara Simion

  14-10-2026

  https://doi.org/10.4081/btvb.2026.690

  21

  PDF: 11

• CO-48 | HEMOFISH: A NEW ANIMAL MODEL FOR STUDY THE ROLE OF FACTOR VIII IN BONE DISEASE M. Berni¹, L. Caliogna¹, F. Tonelli², C. Aresi², G. Rizzi¹, A. Forlino², G. Pasta¹ | ¹Orthopedics and Traumatology Clinic, IRCCS Policlinico San Matteo Foundation, Pavia, Italy; ²Dep. of Molecular Medicine, Biochemistry Unit, University of Pavia, Italy

  Micaela Berni

  14-10-2026

  https://doi.org/10.4081/btvb.2026.658

  25

  PDF: 9

• CO-35 | TRANSITION FROM A PAEDIATRIC REFERRAL CENTER TO AN ADULT CENTER IN INHERITED BLEEDING DISORDERS: A REAL-WORLD COHORT STUDY I. Ricca¹, A. Casson¹, T. Martini², B. Borsellino², A. Barchieri¹, G. Guido¹, P. Ocello¹, M. Tucciarone¹, R. Albiani², B. Pollio², G. Delios¹ | ¹Centro Malattie Trombotiche ed Emorragiche - SC Servizio Trasfusionale ASL TO4, Ivrea, Italy; ²Centro Esperto Malattie Emorragiche Congenite in Età Pediatrica e della Donna in Gravidanza - SSD Medicina Trasfusionale Materno-Infantile e Traumatologica, Città della Salute e della Scienza di Torino, Italy

  Irene Ricca

  14-10-2026

  https://doi.org/10.4081/btvb.2026.645

  20

  PDF: 6
• 

  Bleeding complications of oral anticoagulant therapy: from ISCOAT to the START Register A memory of Gualtiero Palareti

  Francesco Marongiu

  10-04-2026

  https://doi.org/10.4081/btvb.2026.457

  1717

  PDF: 240
• 

  Thrombosis and hemostasis at the University of Padua: a reappraisal on the occasion of its 800th year of history

  Paolo Simioni, Vittorio Pengo, Paolo Prandoni

  07-11-2022

  https://doi.org/10.4081/btvb.2022.52

  2795

  PDF: 446

• PO20 | Impact of endovascular treatment on functional outcome in ischemic stroke: a real-world retrospective study M.G. Mosconi¹, G. Maraziti¹, M. Paciaroni², J. Fagotti³, V. Caso¹ | ¹Azienda Ospedaliera di Perugia; ²Università degli Studi di Ferrara; ³Ospedale San Giovanni Battista, Foligno (PG), Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.280

  652

  PDF: 16

• CO-60 | A TURNING POINT IN THE MANAGEMENT OF HEMOPHILIA B WITH INHIBITORS: OUTCOMES OF CONCIZUMAB PROPHYLAXIS IN TWO CHILDREN FROM EXPLORER10 G. Quintavalle¹, A. Matichecchia¹, M.I. Tassoni¹, B.M. Roccon¹, F. Riccardi¹, R.P. Serra², A. Tiri², P. Bertolini², A. Tagliaferri¹, A. Coppola¹ | ¹Regional Hub Center for Hemophilia and Congenital Bleeding Disorders, University Hospital of Parma, Italy; ²Pediatric Hematology-Oncology Unit, University Hospital of Parma, Italy

  Antonio Coppola

  14-10-2026

  https://doi.org/10.4081/btvb.2026.670

  23

  PDF: 11

• BEST-05 | LONG-TERM EMICIZUMAB PROPHYLAXIS IN PEOPLE WITH HEMOPHILIA A: REAL-WORLD EXPERIENCE ACROSS ALL AGES A. Colombo¹, I. Quaglia¹, M.R. Fasulo¹, C. Lodigiani¹, M.E. Mancuso^1|2 | ¹Center for Thrombosis and Hemorrhagic Diseases, IRCCS Humanitas Research Hospital, Rozzano, Milano, Italy; ²Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milano, Italy

  Arianna Colombo

  14-10-2026

  https://doi.org/10.4081/btvb.2026.605

  67

  PDF: 9
• 

  PO03 | HEPATIC FIBROSIS–DRIVEN TISSUE FACTOR EXPRESSION BY MALIGNANT CHOLANGIOCYTES IS ASSOCIATED WITH CANCER-ASSOCIATED THROMBOSIS AND POOR SURVIVAL IN INTRAHEPATIC CHOLANGIOCARCINOMA L. Fabris^1|2|3, Y. Frión-Herrera¹, C. Venturin^1|3, M. Cadamuro⁴, J. Gasparello⁵, C. M. Radu^1|2, M. Fassan^1|5, C. Mescoli⁶, U. Cillo^7|8, E. Gringeri^7|8, G. Zanus^7|9, E. Campello^1|2, M. Strazzabosco³, P. Simioni^1|2 | ¹Department of Medicine, University of Padua; ²Clinical Medicine 1 and Thrombotic and Haemorrhagic Disease Unit, and Haemophilia Center, Padua University-Hospital; ³Department of Internal Medicine, Digestive Disease Section, Liver Center, Yale University, New Haven, CT, USA; ⁴School of Medicine and Surgery, University of Milan-Bicocca, Milan, Italy; ⁵Pathology Unit, Ca' Foncello Hospital, ULSS2 Marca Trevigiana, Treviso; ⁶Pathology Unit, Padua University-Hospital; ⁷Department of Surgery, Oncology and Gastroenterology, University of Padua; ⁸Hepatobiliary Surgery and Liver Transplantation Unit, Padua University-Hospital; ⁹General Surgery Unit, Ca' Foncello Hospital, ULSS2 Marca Trevigiana, Treviso, Italy

  ICTHIC 2026

  16-04-2026

  https://doi.org/10.4081/btvb.2026.499

  503

  PDF: 97