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• PO65 | Utilization of emicizumab in acquired hemophilia A: a case report C. Caputo, P. Conca, I.L. Calcaterra, E. Cimino, M. Romeo, M. Aversano, E. Franco, C. De Luca, G. D’errico, L. Jr Valletta, M. Di Minno, A. Tufano | Department of Clinical Medicine and Surgery, Federico II University, Naples, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.334

  628

  PDF: 26
• 

  Diagnosis and management of abnormal uterine bleeding in adolescence An expert Consensus Statement of SIGO (Italian Society of Gynecology and Obstetrics) and SISET (Italian Society for the Study of Hemostasis and Thrombosis)

  Roberto Mario Santi, Annamaria Fulghesu, Ezio Zanon, Erica De Candia, Elvira Grandone, Giancarlo Di Renzo, Claudia Succu, Valentina Tosto, Vincenzina Bruni, Paolo Gresele

  08-05-2024

  https://doi.org/10.4081/btvb.2024.106

  2859

  PDF: 739

• CO-67 | CONGENITAL DYSFIBRINOGENEMIA: BLEEDING PHENOTYPE, THROMBOTIC COMPLICATIONS, AND LONG-TERM MANAGEMENT IN A MULTICENTER COHORT M. Biglietto^1|2, M. Presti¹, R.C. Santoro³, I. Nichele⁴, M. Napolitano⁵, S. Pasca⁶, A. Borchiellini⁷, B. Pollio⁸, E. Zanon⁹, G. Barillari¹⁰, A. Poz¹⁰, S. Sorella¹, S. Ligia¹, R. Mormile¹, E. Baldacci¹, G. Castaman¹¹, F. Peyvandi^12|13, C. Santoro¹ | ¹Hematology, Department of Translational and Precision Medicine, Sapienza University of Rome, Italy; ²Department of Molecular Biology, Sapienza University of Rome, Italy; ³Hemostasis and Thrombosis Unit, Azienda Ospedaliera Pugliese-Ciaccio, Catanzaro, Italy; ⁴Hematology Unit, Azienda ULSS 8 Berica - San Bortolo Hospital, Vicenza, Italy; ⁵Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, University of Palermo, Italy; ⁶Coagulation Diseases Center, Transfusion Medicine Department - Azienda Sanitaria Universitaria Integrata del Trentino, Trento, Italy; ⁷Centro di Riferimento Regionale Malattie Emorragiche e Trombotiche dell'Adulto, Divisione di Ematologia, Università Città della Salute e della Scienza di Torino, Italy; ⁸SIMT Immunohematology and Transfusion Medicine Service, Diagnostic Department, A.O. Città della Salute e della Scienza, Torino, Italy; ⁹Department of Medicine, Haemophilia Centre, University Hospital of Padua, Italy; ¹⁰Center for Hemorrhagic and Thrombotic Diseases, General and University Hospital S. Maria della Misericordia, Udine, Italy; ¹¹Centre for Bleeding Disorders and Coagulation, Careggi University Hospital, Firenze, Italy; ¹²IRCCS Fondazione Ca' Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Milano, Italy; ¹³Università degli Studi di Milano, Department of Pathophysiology and Transplantation, Milano, Italy

  Mario Biglietto

  14-10-2026

  https://doi.org/10.4081/btvb.2026.677

  46

  PDF: 13

• CO-19 | A CASE OF LOSS OF EFFICACY OF EMICIZUMAB AFTER 6 YEARS OF REGULAR USE M.R. Fasulo¹, I. Quaglia¹, A. Colombo¹, C. Lodigiani¹, M.E. Mancuso^1|2 | ¹Center for Thrombosis and Hemorrhagic Diseases, IRCCS Humanitas Research Hospital, Rozzano, Milano, Italy; ²Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milano, Italy

  Maria Rosaria Fasulo

  14-10-2026

  https://doi.org/10.4081/btvb.2026.629

  45

  PDF: 16
• 

  Comparison among three different bleeding scores and the thrombin generation assay to assess the different hemorrhagic phenotypes in patients with FVII deficiency

  Samantha Pasca, Cristina Santoro, Chiara Ambaglio, Marisanta Napolitano, Marta Milan, Letizia Natali, Silvia Nannizzi, Filippo Mori, Paolo Simioni, Ezio Zanon

  23-05-2022

  https://doi.org/10.4081/btvb.2022.12

  5660

  PDF: 546
• 

  Inherited platelet function disorders: a comprehensive narrative review focusing on diagnostic and management aspects

  Antonietta Ferretti, Nicola Portesi, Chiara Gorio, Marzia Leotta, Alessandra Strangio, Antonella Ierardi, Bianca Maria Roccon, Giulia Albrici, Giulia Carracchia, Marta Mattana, Chiara Biasoli, Cristina Santoro, Tiziano Martini, Rita Carlotta Santoro

  21-10-2026

  https://doi.org/10.4081/btvb.2026.581

  56

  PDF: 38

  SUPPLEMENTARY MATERIAL: 12

• PO047 | TRANSIENT IDIOPHATIC ACQUIRED VON WILLEBRAND SYNDROME: A RARE CHALLENGING CONDITION WITH A POSSIBLE RAPIDLY AND FAVOURABLE EVOLUTION G. Murante^1|2|4, S. Bergonzi^1|2|4, M. Capetta^1|2|4, F. Valeri^1|2, C. Dainese^1|2, A. Valpreda³, R. Pastorino^1|4, F. Bocchi^1|4, B. Bruno^2|4, A. Borchiellini^1|2 | ¹Regional Centre for Hemorrhagic and Thrombotic Diseases; ²Division of Hematology; ³Central Lab. Baldi and Riberi, AOU Città della Salute e della Scienza di Torino, Italy; ⁴Dep. of Molecular Biotechnology and Health Sciences, University of Turin, Italy

  Giovanni Murante

  26-10-2026

  https://doi.org/10.4081/btvb.2026.863

  25

  PDF: 10

• CO-10 | APPLICATIONS OF ARTIFICIAL INTELLIGENCE IN HEMOPHILIA MANAGEMENT: INNOVATIONS AND FUTURE PERSPECTIVES A. Ierardi, M. Leotta, A. Strangio, S. Prejanò, R.C. Santoro | UO Hemophilia, Hemostasis and Thrombosis. Azienda Ospedaliero Universitaria Renato Dulbecco, Catanzaro, Italy

  Antonella Ierardi

  14-10-2026

  https://doi.org/10.4081/btvb.2026.620

  90

  PDF: 17

• CO-80 | EMICIZUMAB PLASMA CONCENTRATIONS AND CLINICAL OUTCOMES IN ACQUIRED HEMOPHILIA A: A REAL-WORLD SINGLE-CENTER EXPERIENCE C. Simion^1|2, E. Zanon^1|2, C. Bulato¹, B. Stocco^1|2, F. Righetto¹, F. Sartorello¹, P. Simioni^1|2 | ¹First Chair of Internal Medicine and Thrombotic and Haemorrhagic Diseases Unit, Department of Medicine, Padova University Hospital, Italy; ²Hemophilia Center, Padova University Hospital, Italy

  Chiara Simion

  14-10-2026

  https://doi.org/10.4081/btvb.2026.690

  42

  PDF: 14
• 

  PO25 | EVOLUTION OF ANTICOAGULANT STRATEGIES AND CLINICAL OUTCOMES IN CANCER-ASSOCIATED THROMBOSIS: A LONGITUDINAL ANALYSIS OF THE START2 REGISTRY ONCO-VTE M. Marchetti^1|2, T. Zollner^1|2, OC. Cretu^1|2, A. Chistolini³, R. Pancani⁴, L. Puccetti⁵, P. Sivera⁶, W. Ageno⁷, G. Elmi⁸, V. Fregoni⁹, V. Tonelli¹⁰, E. Antonucci¹¹, D. Poli^11|12, A. Falanga^1|2, L. Barcella^1|2 | ¹Hemostasis & Thrombosis Center, Department of Transfusion Medicine, Papa Giovanni XXIII Hospital, Bergamo Italy; ²ERN EuroBloodNet; ³Hematology Unit, Department of Translational and Precision Medicine, Sapienza University of Rome, Rome, Italy; ⁴Pulmonary Unit, Hospital of Siena, University of Siena, Siena, Italy; ⁵Hemostasis and Thrombosis Unit, Hospital of Siena, University of Siena, Siena, Italy; ⁶Haematology Unit, Ordine Mauriziano Hospital, Turin, Italy; ⁷Department of Medicine, University of Padua, Padua, Italy; ⁸Department of Medicine, Maggiore Hospital, Bologna, Italy; ⁹Department of Medicine, Sondalo Hospital, Sondalo, Italy; ¹⁰Angiology Unit, Sant'Eugenio Hospital, Rome, Italy; ¹¹Arianna Anticoagulazione Foundation, Bologna, Italy; ¹²Department of Critical Care Medicine, Thrombosis Centre, Azienda Ospedaliera Universitaria Careggi, Firenze, Italy

  ICTHIC 2026

  16-04-2026

  https://doi.org/10.4081/btvb.2026.520

  440

  PDF: 90

• PO50 | Treatment with BTK inhibitors in patients affected by chronic lymphocytic leukemia: safety and hemostasis L. Gurgoglione, C.A. Piro, I. Scortechini, I. Battilà, M.C. Merlo, A. R. Scortechini, S. Rupoli, A. Poloni | Hematology Unit, AOU delle Marche-Università Politecnica delle Marche, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.319

  525

  PDF: 15

• CO-66 | PREGNANCY OUTCOMES AND PERIPARTUM MANAGEMENT IN WOMEN WITH CONGENITAL FIBRINOGEN DISORDERS: A SINGLE-CENTRE EXPERIENCE T. Martini¹, B. Borsellino^1|2, B. Pollio¹ | ¹Haemophilia Centre, Immune-Haematology and Transfusion Medicine, University Hospital “Città della Salute e della Scienza”, Torino, Italy; ²Department of Biomedicine and Prevention, PhD in Immunology, Molecular Medicine and Applied Biotechnology, University of Rome Tor Vergata, Roma, Italy

  Tiziano Martini

  14-10-2026

  https://doi.org/10.4081/btvb.2026.676

  42

  PDF: 14

• CO-73 | WHEN BLEEDING MIMICS THROMBOSIS: DIAGNOSTIC DELAY AND THROMBOTIC COMPLICATIONS IN ACQUIRED HEMOPHILIA A R. Tomasello¹, M. Mattana¹, S. Raso¹, F. Schirò¹, P. Polidori², M.I. Di Lena³, F. La Gattuta⁴, M. Napolitano¹ | ¹Ematologia e malattie rare, PO Cervello di Palermo, Italy; ²Farmacia ospedaliera, PO Cervello di Palermo, Italy; ³Direzione medica, PO Cervello di Palermo, Italy; ⁴Radiologia interventistica, PO Villa Sofia di Palermo, Italy

  Riccardo Tomasello

  14-10-2026

  https://doi.org/10.4081/btvb.2026.683

  53

  PDF: 12

• CO-26 | CLINICAL, LABORATORY AND METABOLIC CHARACTERISTICS OF ADULT PATIENTS WITH HEMOPHILIA A J. Di Paolo, M. Di Loreto, R. Malizia, M. Luongo, P. Massaro, M. Di Mascio, S. Verna | Immunohematology Service, Asl 02 Abruzzo, Chieti, Italy

  Josephine Di Paolo

  14-10-2026

  https://doi.org/10.4081/btvb.2026.636

  36

  PDF: 15

• PO92 | Challenging management of portal vein thrombosis in a cirrhotic patient on hormone therapy after breast cancer L. Jr Valletta, C. De Luca, M. Aversano, C. Caputo, E. Cimino, P. Conca, A. Tufano, M.D. Di Minno | AOU Federico II Napoli, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.362

  570

  PDF: 18
• 

  A case of acquired factor XIII deficiency secondary to plasmablastic lymphoma

  Vincenzo Sammartano, Adele Santoni, Elisabetta Zappone, Paola Calzoni, Daniela Fineschi, Eleonora Franceschini, Federico Caroni, Anna Sicuranza, Monica Bocchia, Luca Puccetti

  09-03-2023

  https://doi.org/10.4081/btvb.2023.53

  1433

  PDF: 571

• CO-65 | COVID-19-ASSOCIATED HYPERCOAGULABILITY IN TYPE 2B VON WILLEBRAND DISEASE: INSIGHTS FROM GLOBAL HEMOSTATIC ASSAYS I. Condonato, C. Simion, E. Zanon, P. Simioni | Hemophilia Center, University Hospital of Padua, Italy

  Irene Condonato

  14-10-2026

  https://doi.org/10.4081/btvb.2026.675

  43

  PDF: 16

• CO33 | Acquired hemophilia A in Liguria, Italy: what six years of data reveal C. Vernarecci¹, A. C. Molinari¹, P. Ballarino², M. Caiti², E. Cenni², P. Moscatelli², L. Banov¹ | ¹IRCCS Istituto Giannina Gaslini, Genova; ²IRCCS Policlinico San Martino, Genova, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.240

  616

  PDF: 30
• 

  Allopurinol-induced acquired von Willebrand syndrome

  Juan Eirís, Marina Suárez-Terrón, Pablo Granados, David Martínez-Campuzano, Ana Rosa Cid, Saturnino Haya, Santiago Bonanad

  25-10-2023

  https://doi.org/10.4081/btvb.2023.88

  2252

  PDF: 386

• CO-58 | SUCCESSFUL TREATMENT WITH EFANESOCTOCOG ALFA OF INTRACRANIAL HEMORRHAGE IN A NEWBORN AFFECTED BY SEVERE HEMOPHILIA A T. Martini¹, B. Borsellino^1|2, B. Pollio¹ | ¹Hemophilia Centre, Immune-Haematology and Transfusion Medicine, University Hospital “Città della Salute e della Scienza”, Torino, Italy; ²Department of Biomedicine and Prevention, PhD in Immunology, Molecular Medicine and Applied Biotechnology, University of Rome Tor Vergata, Roma, Italy

  Tiziano Martini

  14-10-2026

  https://doi.org/10.4081/btvb.2026.668

  48

  PDF: 14

• CO-31 | WHEN NECK PAIN HIDES A SPINAL BLEED: ANTERIOR CERVICAL EPIDURAL HEMATOMA IN A CHILD WITH HEMOPHILIA B E. Dalla Porta, C. Simion, E. Zanon, B. Stocco, L. Spiezia, P. Simioni | Hemophilia Center, University Hospital of Padua, Italy

  Edoardo Dalla Porta

  14-10-2026

  https://doi.org/10.4081/btvb.2026.641

  43

  PDF: 16

• PO47 | Hemophilia A and antithrombin deficiency: a case of natural hemostatic rebalancing L. Torrieri, S. Ligia, E. Baldacci, R. Mormile, S. Sorella, R. Ciciani, M. Biglietto, N. Zhdanovskaya, A. Delli Paoli, A. Tirnetta, M. Lorenzon, C. Santoro | Hematology, Department of Translational and Precision Medicine, Policlinico Umberto I, Sapienza University of Roma, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.316

  633

  PDF: 13

• CO-14 | BEYOND BLEEDING: NARRATIVE MEDICINE AS A METHODOLOGICAL TOOL FOR INVESTIGATION AND CARE IN CONGENITAL BLEEDING DISORDERS V. Grippa¹, S. Riva², A. Gringeri³ | ¹Centro Malattie Emorragiche Salerno, Italy; ²St. Mary's University, London, UK; ³Fondazione Charta, Milano, Centro di Solidarietà Solidale, Lucca, Italy

  Silvia Riva

  14-10-2026

  https://doi.org/10.4081/btvb.2026.624

  72

  PDF: 19
• 

  PO64 | MANAGEMENT OF BLEEDING RISK IN PATIENTS WITH HEPATOCELLULAR CARCINOMA RECEIVING SYSTEMIC THERAPY: A SURVEY OF CLINICAL PRACTICE T. Van Broeckhoven^1|9, E. Van Gansewinkel^5|10, J. De Bruijne², F. Eskens³, D. De Groot⁴, K. Hermans⁵, N. Mohammad⁶, F. Van Vilsteren⁷, C. Verslype⁸, W. Moris⁹, M. Roest¹⁰, B. De Laat¹⁰ , J. De Vos-Geelen⁵, M. Kramer^1|9 | ¹Department of Gastroenterology and Hepatology, GROW – Research Institute for Oncology and Reproduction, Maastricht University Medical Center, Maastricht, The Netherlands; ²Department of Gastroenterology & Hepatology, Utrecht University, University Medical Center Utrecht, The Netherlands; ³Department of Medical Oncology, Erasmus Medical Centre, Rotterdam, the Netherlands; ⁴Department of Medical Oncology, University Medical Centre Groningen, University of Groningen, the Netherlands; ⁵Department of Internal Medicine, Division of Medical Oncology, GROW – Research Institute for Oncology & Reproduction, Maastricht University Medical Center, Maastricht, The Netherlands; ⁶Department of Medical Oncology, University Medical Centre Utrecht, Utrecht University, Utrecht, the Netherlands; ⁷Department of Gastroenterology and Hepatology, University Medical Centre Groningen, Groningen, The Netherlands; ⁸Digestive Oncology, University Hospitals Leuven, Belgium; ⁹Department of Gastroenterology and Hepatology, Maastricht University Medical Center, Maastricht, The Netherlands; ¹⁰Department of Functional Coagulation, Synapse Research Institute, Maastricht, The Netherlands, on behalf of the Dutch Hepatocellular & Cholangiocarcinoma Group

  ICTHIC 2026

  16-04-2026

  https://doi.org/10.4081/btvb.2026.554

  447

  PDF: 97

• PO81 | Direct oral anticoagulants in atypical site vein thrombosis: a single centre experience focused on cancer patients U. Mazzarelli¹, A. Guida¹, L. Agrelli¹, M. Amato¹, R. Guarrasi², L. Santaniello², C. Cardamone¹, P. Vitale¹, M. Triggiani¹ | ¹Centro per le Malattie Emorragiche Congenite e Malattie Trombotiche UOC Clinica Immunologica e Reumatologica AOU S. Giovanni di Dio e Ruggi d’Aragona, Salerno; ²UOC Clinica Oncologica AOU S. Giovanni di Dio e Ruggi d’Aragona, Salerno, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.350

  637

  PDF: 23

• PO37 | Single centre experience on anticoagulation in carriers of non-mild inherited thrombophilia: direct oral anticoagulants (DOAC) efficacy and safety M. D’uva^1,2, G. La Barba¹, G. Montanaro¹, M. Di Ianni^1,2, P. Ranalli^1,2 | ¹Hematology Unit, S. Spirito Hospital, Pescara; ²Department of Medicine and Aging Sciences, D’Annunzio University, Chieti, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.300

  651

  PDF: 22

• PO149 | MANAGEMENT OF ANTITHROMBOTIC THERAPY IN A PATIENT WITH HEMOPHILIA C AND ATRIAL FIBRILLATION E. Marrone¹, G. Ruggiero², E. Cimino³, P. Conca³, C. Miele⁴, F. Gallucci¹, A. Abate¹, C. Romano¹, D. Leosco², U. Valentino¹ | ¹Department of Medicine 3, Cardarelli Hospital, Napoli, Italy; ²School of Specialization in Geriatrics; ³Department of Internal Medicine and Blood Coagulation; ⁴Department of Laboratory Medicine and Transfusion, Federico II University, Napoli, Italy

  Emiliana Marrone

  26-10-2026

  https://doi.org/10.4081/btvb.2026.965

  24

  PDF: 8
• 

  PO30 | LONG-TERM ANTICOAGULANT THERAPY AND PREVENTION OF RECURRENT VENOUS THROMBOEMBOLISM IN ADVANCED OVARIAN CANCER V. Bitsadze ¹, A. Vorobev ¹, J. Khizroeva ¹, A. Solopova ¹, M. Tretyakova ¹, N. Gashimova ¹, K. Grigoreva ¹, A. Khisamieva ¹, J. Gris ^1|2, I. Elalamy^1|3|4, G. Gerotziafas^1|3|4, A. Makatsariya¹ | ¹Department of Obstetrics, Gynecology and Perinatal Medicine, N. F. Filatov Clinical Institute of Children’s Health, I. M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia; ²Faculty of Pharmaceutical and Biological Sciences, Montpellier University, France; ³Department Hematology and Thrombosis Center, Medicine Sorbonne University, Paris, France; ⁴Hospital Tenon, Paris, France

  ICTHIC 2026

  16-04-2026

  https://doi.org/10.4081/btvb.2026.525

  473

  PDF: 98

• CO-77 | PERINATAL MANAGEMENT IN WOMAN WITH MILD HEMOPHILIA B: A TWIN PREGNANCY CASE T. Martini¹, B. Borsellino^1|2, B. Pollio¹ | ¹Haemophilia Centre, Immune-Haematology and Transfusion Medicine, University Hospital “Città della Salute e della Scienza”, Torino, Italy; ²Department of Biomedicine and Prevention, PhD in Immunology, Molecular Medicine and Applied Biotechnology, University of Rome Tor Vergata, Roma, Italy

  Tiziano Martini

  14-10-2026

  https://doi.org/10.4081/btvb.2026.687

  40

  PDF: 14

• CO-30 | AL AMYLOIDOSIS IN A PATIENT WITH SEVERE HEMOPHILIA A AND INHIBITORS WHO HAD A MONOZYGOTIC TWIN: SAME GENES, DIFFERENT OUTCOMES M. Biglietto^1|2, S. Sorella¹, S. Ligia¹, C. Andriola¹, R. Mormile¹, E. Baldacci¹, A. Chistolini¹, C. Santoro¹ | ¹Hematology, Department of Translational and Precision Medicine, Sapienza University of Rome, Italy; ²Department of Molecular Biology, Sapienza University of Rome, Italy

  Mario Biglietto

  14-10-2026

  https://doi.org/10.4081/btvb.2026.640

  45

  PDF: 18

• PO110 | CLINICAL OUTCOMES AND SURVIVAL OF UNUSUAL SITE VENOUS THROMBOSIS IN PATIENTS WITH AND WITHOUT MYELOPROLIFERATIVE NEOPLASMS: A RETROSPECTIVE SINGLE-CENTER STUDY I. Bertozzi, M.T. Sartori, G. Libralon, M. Zerbinati, A. Galbiati, P. Simioni | Department of Medicine, University of Padova, Italy

  Irene Bertozzi

  26-10-2026

  https://doi.org/10.4081/btvb.2026.926

  24

  PDF: 9

• PO42 | Acquired Von Willebrad syndrome in patients with myeloproliferative syndrome: literature review and single-center experience A. Strangio, M. Leotta, A. Ierardi, R C. Santoro | UO Emofilia, Emostasi e Trombosi, AOU R Dulbecco, Catanzaro, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.305

  558

  PDF: 22

• PO102 | EFFICACY AND SAFETY OF VISCOELASTIC TESTING–GUIDED TRANSFUSION IN CIRRHOSIS UNDERGOING INVASIVE PROCEDURES: A META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS A. Boccatonda¹, E. Campello², A. Napolitano², C. Simion², C. Serra¹, P. Simioni² | ¹Diagnostic and Therapeutic Interventional Ultrasound Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Policlinico Sant'Orsola-Malpighi, Via Massarenti N 9, 40138, Bologna, Italy; ²First Chiar of Internal Medicine and Thrombotic and Hemorrhagic Diseases Unit, Department of Medicine, University Hospital of Padova, 35128, Padova, Italy

  Andrea Boccatonda

  26-10-2026

  https://doi.org/10.4081/btvb.2026.918

  20

  PDF: 8

• CO090 | DIRECT ORAL ANTICOAGULANTS IN THE SECONDARY PREVENTION OF VENOUS THROMBOEMBOLISM IN PATIENTS WITH SEVERE INHERITED THROMBOPHILIA: A REAL-WORLD MULTICENTER STUDY A. Tufano¹, I.L. Calcaterra¹, E. Valeriani², E. Cimino¹, P. Madonna³, A. Guida⁴, P. Rufolo¹, F. Strano¹, R. Russo¹, A. Casoria⁵, M. Amitrano⁵, P. Pignatelli², M. Di Minno¹ | ¹Department of Clinical Medicine and Surgery, University of Naples, Federico II, Napoli, Italy; ²Department of Internal Medicine, Endocrine and Metabolic Sciences, and Infectious Diseases. Umberto I Hospital of Roma, Italy; ³Thrombotic Unit, Ospedale del Mare, Napoli, Italy; ⁴Center for Congenital Bleeding Disorders and Thrombosis, AOU S.Giovanni di Dio and Ruggi d'Aragona, Salerno, Italy; ⁵UOC Medicina Interna, AORN Moscati, Avellino, Italy

  Antonella Tufano

  26-10-2026

  https://doi.org/10.4081/btvb.2026.792

  30

  PDF: 11

• CO-56 | EVALUATING AN AI MODEL’S HEMATOLOGY CONSULTATION PERFORMANCE FOR HOSPITALIZED PATIENTS WITH BLEEDING DISORDERS G. Sottilotta¹, F. Misiti², G. Praticò¹, D. Megalizzi¹, F. Luise³ | ¹UOSD Microcitemie - Emostasi e Trombosi. Grande Ospedale Metropolitano di Reggio Calabria, Italy; ²Associazione Emofilici di Reggio Calabria, Italy; ³Laboratorio Analisi. Grande Ospedale Metropolitano di Reggio Calabria, Italy

  Gianluca Sottilotta

  14-10-2026

  https://doi.org/10.4081/btvb.2026.666

  46

  PDF: 17

• PO011 | A TWO CENTERS REAL-WORLD EXPERIENCE WITH ANTI-XA DIRECT ORAL ANTICOAGULANTS IN CANCER PATIENTS WITH UNUSUAL SITE VEIN THROMBOSIS U. Mazzarelli¹, L. Agrelli¹, A. Cirillo¹, C. Caputo², M. Romano², R. Russo², R. Guarrasi³, M. Triggiani¹, A. Tufano², A. Guida⁴ | ¹Dipartimento di Medicina Interna, Università degli studi di Salerno, Italy; ²Dipartimento di Medicina Interna, Università degli studi di Napoli Federico II, Italy; ³UOC Clinica Oncologica; ⁴Centro per le malattie emorragiche congenite e malattie trombotiche AOU San Giovanni di Dio e Ruggi d'Aragona Salerno, Italy

  Anna Guida

  26-10-2026

  https://doi.org/10.4081/btvb.2026.827

  32

  PDF: 8

• CO38 | Management of pregnancy, delivery, and postpartum in Italian carriers and women with hemophilia A and B S. Linari¹, B. Pollio², A. Ferretti³, M. Napolitano⁴, E. Grandone⁵, S. Siboni⁶, Ab. Aru⁷, E. Bertoni⁸, C. Biasoli⁹, I. Cantori¹⁰, P. Di Gregorio¹¹, G. Lassandro¹², G. Sottilotta¹³, A. Strangio¹⁴, Mr. Villa¹⁵, A. Rocino¹⁶, G. Castaman¹ | ¹Center for Bleeding Disorders and Coagulation, Careggi University Hospital, Firenze; ²Regional Reference Center for Inherited Bleeding and Thrombotic Disorders, Transfusion Medicine, Regina Margherita Children Hospital, Turin; ³Center for Hemorrhagic and Thrombotic Diseases, IRCCS A. Gemelli University Hospital Foundation, Roma; ⁴Department of Health Promotion, Maternal-Childhood, Internal Medicine of Excellence G. D’Alessandro, University of Palermo; ⁵Thrombosis and Hemostasis Unit, Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo; ⁶Angelo Bianchi Bonomi Hemophilia and Thrombosis Center and Fondazione Luigi Villa, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan; ⁷Pediatric Onco-Hematology Center, Microcitemico Hospital Cagliari; ⁸Pediatric Oncohematology and Bone Marrow Transplant “BMT” Unit, Children’s Hospital, Spedali Civili, Brescia; ⁹Hemophilia and Transfusion Center, Bufalini Hospital, Cesena; ¹⁰Hemophilia Center, Department of Transfusion Medicine, Hospital of Macerata; ¹¹Transfusion Medicine Department, SS. Annunziata Hospital, Chieti; ¹²B. Trambusti General and Specialised Pediatrics Unit, Giovanni XXIII Hospital, University of Bari; ¹³Hemophilia Center, Grande Ospedale Metropolitano, Reggio Calabria; ¹⁴Center for Hemorrhagic and Thrombotic Disorders, Pugliese Ciaccio Hospital, Catanzaro; ¹⁵Hemophilia and Thrombosis Center, Haematology Unit, Ospedale del Mare Hospital, Naples; ¹⁶Past President of the Italian Association of Hemophilia Centers, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.245

  586

  PDF: 15

• CO012 | LONG-TERM RISK OF RECURRENT VENOUS THROMBOEMBOLISM IN ADULT PATIENTS WITH ACTIVE CANCER AND FIRST CATHETER-RELATED UPPER EXTREMITY DEEP VEIN THROMBOSIS AFTER DISCONTINUATION OF ANTICOAGULANT TREATMENTS AND LINE REMOVAL: A RETROSPECTIVE MULTI-CENTER COHORT STUDY – CANCER-CRT STUDY L. Girardi^1|2, W. Ageno³, L. Bertù¹, C. Lodigiani⁴, L.A. Ciuffini⁴, M.C. Vedovati⁵, C. Becattini⁵, A. Sammarco⁶, G. Camporese⁶, G. Cuni^1|7, C. Ambaglio⁷, M.P. Donadini¹ | ¹Research Center on Thromboembolic Diseases and Antithrombotic Treatment, Department of Medicine and Surgery, University of Insubria, Varese, Italy; ²Department of Medicine, The Ottawa Hospital Research Institute, University of Ottawa, Ontario, Canada; ³Department of Medicine, University of Padua, Padova, Italy; ⁴Center for Thrombosis and Hemorrhagic Diseases, IRCCS Humanitas Research Hospital, Rozzano, Milano, Italy; ⁵Internal and Cardiovascular Medicine-Stroke Unit, University of Perugia, Perugia, Italy; ⁶Clinica Medica 1, Department of Medicine, DIMED, Padova University Hospital, Padova, Italy; ⁷Immunohematology and Transfusion Medicine, Department of Transfusion Medicine and Hematology, ASST Papa Giovanni XXIII, Bergamo, Italy

  Laura Girardi

  26-10-2026

  https://doi.org/10.4081/btvb.2026.714

  35

  PDF: 9
• 

  PO53 | PHASE 3 TRIAL EVALUATING THE EFFICACY AND SAFETY OF REGN7508^CAT FOR PRIMARY PROPHYLAXIS OF CANCER-ASSOCIATED THROMBOSIS FOR PARTICIPANTS WITH SOLID TUMORS UNDERGOING CANCER TREATMENT (ROXI-CAT-I) J. Zwicker¹, M. P. O’Brien², M. Carrier³, J. Connors⁴, A. Falanga⁵, A. Manzano⁶, R. Mcbane⁷, Y.Y. Janjigian¹, G. O’Kane⁸, M. Onisko², J. Kaplan², A.P. Kithcart², D.E. Gutstein², A. Khorana⁹, M. F. Walsh² | ¹Memorial Sloan Kettering Cancer Center, New York, USA; ²Regeneron Pharmaceuticals, Inc. , Tarrytown, NY, USA; ³University of Ottawa, Ottawa, ON, Canada; ⁴Harvard Medical School, Boston, MA, USA; ⁵Hospital Papa Giovanni XXIII, Bergamo, Italy; ⁶Hospital Universitario 12 de Octubre, Madrid, Spain; ⁷Mayo Clinic, Rochester, MN, USA; ⁸St. Vincent's University Hospital and School of Medicine, University College Dublin, Dublin, Ireland; ⁹James P. Wilmot Cancer Center and the Department of Medicine, University of Rochester, Rochester, NY, USA

  ICTHIC 2026

  16-04-2026

  https://doi.org/10.4081/btvb.2026.545

  517

  PDF: 123
• 

  Anticoagulation challenges in patients with hematological malignancy-associated thrombosis and severe thrombocytopenia

  Emilie Chalayer, Géraldine Poenou, Corinne Frere

  16-04-2026

  https://doi.org/10.4081/btvb.2026.429

  389

  PDF: 172

• CO049 | RANDOMIZED CONTROLLED TRIAL TO IDENTIFY THE OPTIMAL SCHEME OF HEPARIN FOR TREATMENT OF DEEP VEIN THROMBOSIS IN PREGNANCY E. Grandone^1|3, E. Antonucci², A. de Laurenzo¹, L. Latino¹, M. Mastroianno¹, G. Tiscia¹, M. Margaglione³, P. Prandoni² | ¹IRCCS Casa Sollievo della Sofferenza, S.Giovanni Rotondo, Italy; ²Fondazione Arianna, Italy; ³Università di Foggia, Italy

  Elvira Grandone

  26-10-2026

  https://doi.org/10.4081/btvb.2026.751

  29

  PDF: 10

• CO-68 | ACQUIRED FACTOR XIII DEFICIENCY ASSOCIATED WITH CROHN’S DISEASE: A CHALLENGING DIAGNOSTIC AND THERAPEUTIC CASE A. Colombo¹, A. Dal Buono^2|3, I. Quaglia¹, C. Novembrino⁴, M.R. Fasulo¹, C. Lodigiani¹, M.E. Mancuso^1|2 | ¹Center for Thrombosis and Hemorrhagic Diseases, IRCCS Humanitas Research Hospital, Rozzano, Milano, Italy; ²Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milano, Italy; ³IBD Center, IRCCS Humanitas Research Hospital, Rozzano, Milano, Italy; ⁴Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico Angelo Bianchi Bonomi, Hemophilia and Thrombosis Center and Fondazione Luigi Villa, Milano, Italy

  Arianna Colombo

  14-10-2026

  https://doi.org/10.4081/btvb.2026.678

  45

  PDF: 12

• PO154 | CORONARY REVASCULARIZATION IN ACUTE CORONARY SYNDROME IN PATIENT WITH MILD HEMOPHILIA B: A CASE REPORT D. Fumarulo, R. Corrado, M. Canfora, M. Mazzetti, M. Littera, D. Prisco, C. Tamburini | Internal Medicine, Careggi Hospital, University of Florence, Firenze, Italy

  Daniela Fumarulo

  26-10-2026

  https://doi.org/10.4081/btvb.2026.970

  21

  PDF: 7
• 

  PO36 | EXTENDED DURATION REDUCED DOSE ANTICOAGULATION IN CANCER-ASSOCIATED THROMBOSIS: A REAL-WORLD COHORT WITH LONG TERM FOLLOW UP A. Bhide¹, I. Welding¹, O. Ogunbiyi¹, S. Hawkins², E. Greenlay¹, N. Prasannan¹, J. Westwood¹, M. Thomas¹ | ¹Department of Clinical Haematology, University College London Hospital, London; ²Data Clinic, University College London, UK; A. Bhide and I. Welding joint First Authors

  ICTHIC 2026

  16-04-2026

  https://doi.org/10.4081/btvb.2026.530

  492

  PDF: 116

• PO005 | EXTENDED ANTICOAGULATION WITH DOACS IN PATIENTS AFFECTED BY HEMATOLOGIC MALIGNANCIES AND VENOUS THROMBOEMBOLISM: DOES LOW DOSE FIT ALL? M. Biglietto, S. Sorella, L.V. Cappelli, B. Mandelli, D. Kasmi, E. Baldacci, A. Chistolini | Sapienza University of Roma, Italy

  Mario Biglietto

  26-10-2026

  https://doi.org/10.4081/btvb.2026.821

  17

  PDF: 8
• 

  Anticoagulation during anti-angiogenic cancer therapy: balancing risks of thrombosis and bleeding

  Nikola Vladic, Florian Moik

  16-04-2026

  https://doi.org/10.4081/btvb.2026.452

  308

  PDF: 175

• PO31 | Comparative analysis of anticoagulant therapy in patients over 90 years old: vitamin K antagonists versus direct oral anticoagulants G. Sottilotta¹, P. Arrigo², S. Cuzzocrea¹, D. Megalizzi¹, F. Luise³ | ¹UOSD Microcitemie, Emostasi e Trombosi, Grande Ospedale Metropolitano di Reggio Calabria; ²Associazione Italiana Pazienti Anticoagulati, Sezione di Reggio Calabria; ³Laboratorio Analisi. Grande Ospedale Metropolitano di Reggio Calabria, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.292

  598

  PDF: 15

• PO026 | AUTOSOMAL DOMINANT ITGA2B AND ITGB3 VARIANTS EXPAND THE PHENOTYPIC SPECTRUM OF ΑIIBΒ3-RELATED PLATELET DISORDERS S. Ferrari, D. Regazzo, L. Onorati, A. Galbiati, L. Spiezia, A. Bertomoro, P. Simioni | Department of Medicine, University of Padova, Italy

  Silvia Ferrari

  26-10-2026

  https://doi.org/10.4081/btvb.2026.842

  24

  PDF: 6

• CO-87 | SPONTANEOUS HEMATOMA IN A PATIENT WITH POLYCYTHEMIA VERA: A CASE OF ACQUIRED VON WILLEBRAND DISEASE? A. Strangio, A. Ierardi, M. Leotta, R.C. Santoro | Hemophilia center, AOU Renato Dulbecco, Catanzaro, Italy

  Alessandra Strangio

  14-10-2026

  https://doi.org/10.4081/btvb.2026.697

  50

  PDF: 17

• PO123 | PERIOPERATIVE MANAGEMENT OF FEMORAL FRACTURE SURGERY IN AN ELDERLY PATIENT WITH ACQUIRED HEMOPHILIA A RECEIVING EMICIZUMAB C. Simion, E. Zanon, B. Stocco, G. Saggiorato, F. Sartorello, C. Bulato, P. Simioni | Department of Medicine, University of Padova, Italy

  Chiara Simion

  26-10-2026

  https://doi.org/10.4081/btvb.2026.939

  20

  PDF: 8

• PO106 | INTERACTIONS BETWEEN DIRECT ORAL ANTICOAGULANTS AND ANTIEPILEPTIC DRUGS (INTER-DOAC): A PROSPECTIVE OBSERVATIONAL STUDY A. Rafanelli¹, C. Pizzanelli³, M. Biagini¹, P. Chiarugi⁴, M. Casini⁴, P. Capozza⁵, G. Guarini⁵, L. Malloggi⁴, G. Siciliano³, R. De Caterina^5|6, L. Carrozzi^1|2, F. Pistelli^1|2, L. Marconi², A. Celi^1|2, R. Pancani² | ¹Pulmonary Division, Dep. of Surgical, Medical and Molecular Pathology and Critical Care Medicine, University of Pisa, Pisa, Italy; ²Pulmonary Unit, Cardiothoracic and Vascular Dep., University Hospital of Pisa, Pisa, Italy; ³Neurology Unit, Dep. of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy; ⁴Clinical Chemistry Laboratory, Dep. of Laboratory Medicine, University Hospital of Pisa, Pisa, Italy; ⁵Cardiology Unit, Cardiothoracic and Vascular Dep., University Hospital of Pisa, Pisa, Italy; ⁶Cardiology Division, Dep. of Surgical, Medical and Molecular Pathology and Critical Care Medicine, University of Pisa, Pisa, Italy

  Annalisa Rafanelli

  26-10-2026

  https://doi.org/10.4081/btvb.2026.922

  24

  PDF: 9

• PO130 | HEMORRHAGIC AND THROMBOTIC COMPLICATIONS DURING DOACS TREATMENT: THE IMPORTANCE OF A REGULAR AND PROLONGED FOLLOW-UP D. Barcellona^1|2, A. Mameli², S. Cornacchini², P. Schirru², L. Fenu², V. Casu², F. Marongiu^1|2 | ¹University of Cagliari, Italy; ²Haemostasis and Thrombosis Unit, Azienda Ospedaliero-Universitaria di Cagliari, Italy

  Doris Barcellona

  26-10-2026

  https://doi.org/10.4081/btvb.2026.946

  32

  PDF: 6

• CO106 | ENDOTHELIAL DYSFUNCTION AS A POSSIBLE ADDITIONAL DRIVER OF BLEEDING IN HERMANSKY–PUDLAK SYNDROME F. Tondi¹, G. Purgatorio¹, E. Giglio¹, E. Petito¹, E. Falcinelli¹, G. Guglielmini¹, P. Gresele¹, C. Olgasi², L. Bury¹ | ¹Dep. of Medicine and Surgery, Section of Internal and Cardiovascular Medicine, University of Perugia, Perugia, Italy; ²Dep. of Translational Medicine, School of Medicine, University of Piemonte Orientale, Novara, Italy

  Francesca Tondi

  26-10-2026

  https://doi.org/10.4081/btvb.2026.808

  23

  PDF: 10

• PO039 | CLINICAL AND LABORATORY CHARACTERISTICS OF ACQUIRED HEMOPHILIA A: PRELIMINARY RESULTS FROM A RETROSPECTIVE OBSERVATIONAL MONOCENTRIC STUDY S. Suardi¹, M. Bodini², A.C. Giuffrida², A. Zanzanelli³, S. Moruzzi¹, L. Delfino¹, F. Pizzolo¹, S. Genesini², M. Cantini², C. Spillere¹, L. Panepinto¹, F. Zoccatelli¹, E. Malloggi¹, F. Presa¹, A. Moschella¹, M. Merlo¹, G. Gandini², S. Friso¹, N. Martinelli¹ | ¹Department of Medicine, Unit of Internal Medicine B, Azienda Ospedaliera Universitaria Integrata di Verona, Italy; ²Department of Transfusion Medicine, Hemophilia Center, Azienda Ospedaliera Universitaria Integrata di Verona, Italy; ³Division of Internal Medicine, IRCCS Azienda Ospedaliero Universitaria Bologna, Italy

  Silvia Suardi

  26-10-2026

  https://doi.org/10.4081/btvb.2026.855

  22

  PDF: 8

• PO003 | CATHETER-RELATED THROMBOSIS IN CANCER PATIENTS: A RETROSPECTIVE REAL-WORLD STUDY G. Autiero^1|3, S.A. Malerba^1|2|4, F. Busato^1|2, D. Tolomio^1|2, M. Dalla Vestra^1|2, F. Presotto^1|2 | ¹U.O. Medicina Generale, Osp. Dell'Angelo, Venezia-Mestre, Italy; ²U.O. Angiologia, Osp. Dell'Angelo, Venezia-Mestre, Italy; ³Dip. Medicina Interna, Università degli Studi di Padova, Italy; ⁴U.O.C. Medicina Generale ad indirizzo trombotico ed emorragico, Università degli studi di Padova, Italy

  Giuliana Autiero

  26-10-2026

  https://doi.org/10.4081/btvb.2026.819

  21

  PDF: 8

• PO105 | IMPACT OF ECOG PERFORMANCE STATUS ON CANCER-ASSOCIATED THROMBOSIS TREATED WITH DOACS: DATA FROM A MULTICENTER COHORT STUDY R. Talerico¹, F. Mancinetti¹, C. Sacco², M. Mazzetti³, E. Campello⁴, S. Birocchi⁵, S. Beccatini⁶, A. Porfidia¹, C. Lodigiani², P. Simioni⁴, G.M. Podda⁵, I. Mastandrea², C. Becattini⁶, R. Pola¹, M.C. Vedovati⁶ | ¹Thrombosis Unit, Department of Geriatric, Orthopedic, and Rheumatologic Sciences, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy; ²Thrombosis and Hemorrhagic Diseases Unit, IRCCS Humanitas Research Hospital, Rozzano, Milano, Italy; ³Interdisciplinary Internal Medicine, Careggi University Hospital, Firenze, Italy; ⁴First Chair of Internal Medicine and Thrombotic and Hemorrhagic Diseases Unit, Department of Medicine, University of Padova, Italy; ⁵Medicine II Unit, ASST Santi Paolo e Carlo, Department of Health Sciences, University of Milano, Milano, Italy; ⁶Internal, Vascular and Emergency Medicine– Stroke Unit, University of Perugia, Perugia, Italy

  Rosa Talerico

  26-10-2026

  https://doi.org/10.4081/btvb.2026.921

  21

  PDF: 9

• PO74 | Combined therapeutic approaches in a patient with hereditary hemorrhagic telangiectasia (HHT) and cardiovascular comorbidities M. Romeo, E. Cimino, P. Conca, I.L. Calcaterra, G. Iannuzzo, C. Caputo, M. Aversano, E. Franc, S. Donnarumma, C. De Luca, M.N.D. Di Minno, A. Tufano | Department of Clinical Medicine and Surgery, Federico II University, Naples, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.343

  765

  PDF: 16

• PO022 | ARTIFICIAL INTELLIGENCE–ASSISTED PREDICTION OF THROMBOTIC AND HEMORRHAGIC COMPLICATIONS IN PATIENTS TREATED WITH VITAMIN K ANTAGONISTS: A RETROSPECTIVE EXPLORATORY STUDY G. Sottilotta¹, F. Misiti², G. Praticò¹, D. Megalizzi¹, F. Luise³ | ¹UOSD Microcitemie - Emostasi e Trombosi; ³Laboratorio Analisi Grande Ospedale Metropolitano di Reggio Calabria, Italy; ²Associazione Emofilici di Reggio Calabria, Italy

  Gianluca Sottilotta

  26-10-2026

  https://doi.org/10.4081/btvb.2026.838

  31

  PDF: 12

• CO043 | LONG TERM TREATMENT WITH VITAMIN K ANTAGONIST IN PEDIATRIC PATIENTS WITH PROSTHETIC HEART VALVE: THE BERGAMO EXPERIENCE T. Zollner¹, C. Ambaglio¹, F. Duca², G. Cuni¹, E. Galimberti¹, O.C. Cretu¹, F. Schieppati¹, F. Zunino¹, V. Brusegan¹, M. Marchetti¹, A. Falanga^1|2, L. Barcella¹ | ¹Immunohematology and Transfusion Medicine, Department of Transfusion Medicine and Hematology, ERN-EuroBloodNet - European Reference Network in Rare Hematological Diseases, ASST Papa Giovanni XXIII, Bergamo, Italy; ²School of Medicine and Surgery, University of Milano-Bicocca, Milano, Italy

  Chiara Ambaglio

  26-10-2026

  https://doi.org/10.4081/btvb.2026.745

  24

  PDF: 9

• CO-79 | ACQUIRED FACTOR XIII DEFICIENCY: AN UNDERDIAGNOSED CAUSE OF DELAYED BLEEDING AFTER PERICARDIOCENTESIS M. Luongo¹, J. Di Paolo¹, G. D’Amico², P. Massaro¹, M. Di Mascio¹, R. Malizia¹, U. Benedetto², S. Verna¹ | ¹Immunohematology Service, Asl 02 Abruzzo, Chieti, Italy; ² Department of Cardiac Surgery, Asl 02 Abruzzo, Chieti, Italy

  Myriam Luongo

  14-10-2026

  https://doi.org/10.4081/btvb.2026.689

  51

  PDF: 15

• PO38 | Rates of hemorrhagic events and hemodialysis circuit thrombosis in patients with end-stage renal disease on hemodialytic treatment receiving a factor-XI inhibitor: a systematic review and meta-analysis D. Santagata, G. Barbui, M.P. Donadini, A. Squizzato | Department of Medicine and Surgery, Research Center on Thromboembolic Disorders and Antithrombotic Therapies, University of Insubria, Varese and Como, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.301

  617

  PDF: 26

• CO-85 | ACQUIRED HEMOPHILIA A IN LIVER CIRRHOSIS: BALANCING HEMOSTASIS BETWEEN HIGH HEMORRHAGIC AND THROMBOTIC RISKS N. Portesi, G. Martini | ASST Spedali Civili di Brescia, Italy

  Nicola Portesi

  14-10-2026

  https://doi.org/10.4081/btvb.2026.695

  43

  PDF: 19

• PO120 | UNEXPLAINED BLEEDING IN A YOUNG WOMAN: A CASE REPORT OF SUPERWARFARIN TOXICITY M. Guarascio¹, A. Ferretti², L. Di Gennaro², M. Comand², E. De Candia² | ¹Internal Medicine Unit, Vito Fazzi Hospital, Lecce, Italy; ²Department of Translational Medicine and Surgery, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Roma, Italy

  Matteo Guarascio

  26-10-2026

  https://doi.org/10.4081/btvb.2026.936

  29

  PDF: 11
• 

  In this issue

  Giovanni de Gaetano, Chiara Cerletti

  10-07-2026

  https://doi.org/10.4081/btvb.2026.578

  1195

  PDF: 67
• 

  Factor XI inhibitors in cancer-associated venous thromboembolism: what’s next?

  Hiranya M. Dave, Mehrie H. Patel, Keith R. McCrae, Alok A. Khorana

  16-04-2026

  https://doi.org/10.4081/btvb.2026.424

  360

  PDF: 195

• PO27 | B-cell lymphoproliferative disorder and acquired coagulopathy: an insidious link C. Caputo, P. Conca, I.L. Calcaterra, E. Cimino, M. Romeo, M. Aversano, E. Franco, C. De Luca, R. Russo, C. Fierarossa, M.N.D. Di Minno, A. Tufano | Department of Clinical Medicine and Surgery, Federico II University, Naples, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.288

  623

  PDF: 15

• CO-64 | REAPPRAISAL OF DESMOPRESSIN FOR MANAGEMENT OF MILD/MODERATE VON WILLEBRAND DISEASE: RESULTS OF A RETROSPECTIVE ANALYSIS IN 127 ITALIAN PATIENTS SUGGEST FURTHER ORGANIZATION OF PROSPECTIVE OBSERVATIONAL STUDIES TO PREDICT DESMOPRESSIN FAILURE WITH IMMEDIATE VWF CONCENTRATES REQUIREMENT A.B. Federici¹, G. Castaman² | ¹Ematologia e Medicina Trasfusionale, Ospedale Luigi Sacco, Polo Didattico Università di Milano, Italy; ²Centro Emofilia e Malattie Emorragiche Regione Toscana, Ospedale Careggi, Firenze, Italy

  Augusto B Federici

  14-10-2026

  https://doi.org/10.4081/btvb.2026.674

  44

  PDF: 15
• 

  A commitment to global collaboration, welcoming international participation and advancing science for the benefit of patients

  Pantep Angchaisuksiri, Wolfram Ruf, Jeffrey Weitz, Sam Schulman, Guy A. Young

  01-07-2025

  https://doi.org/10.4081/btvb.2025.188

  1643

  PDF: 338

  HTML: 130

• CO-44 | EVALUATION OF THE DEVIATION BETWEEN PRESCRIBED AND RECOMMENDED EMICIZUMAB DOSING IN PATIENTS WITH CONGENITAL HEMOPHILIA A A.C. Giuffrida¹, S. Abeysinghe Gunawardhana¹, S. Amato², F. Casoli², C. Recchi², M. Saggioro², E. Bonetti³, M. Bodini¹, G. Poli² | ¹Centro Emofilia, UOC Medicina Trasfusionale, AOUI Verona, Italy; ²UOC Laboratorio Analisi, AOUI Verona, Italy; ³UOC Oncoematologia Pediatrica, AOUI Verona, Italy

  Marco Bodini

  14-10-2026

  https://doi.org/10.4081/btvb.2026.654

  44

  PDF: 14

• PO001 | EMERGENCY DEPARTMENT MANAGEMENT OF PULMONARY EMBOLISM IN CANCER PATIENTS: PROGNOSTIC STRATIFICATION AND OUTCOMES A. Decursu¹, L. Galli², LM. Caiano², S. Bozzato², E. Ruggeri¹, F. Paletta³, L. Vulcano¹, L. Bertù¹, F. Cortellaro², W. Ageno⁴, MP. Donadini^1|2 | ¹Università degli studi dell'Insubria, Italy; ²ASST Sette Laghi, Italy; ³Università degli studi di Milano-Bicocca, Italy; ⁴Università degli studi di Padova, Italy

  Alessandro Decursu

  26-10-2026

  https://doi.org/10.4081/btvb.2026.817

  26

  PDF: 9

• PO43 | Extended treatment with reduced dose of direct oral anticoagulants in patients with venous thromboembolism: a retrospective study A. Pannunzio¹, E. Valeriani¹, I.M. Palumbo¹, D. Menichelli¹, T. Brogi², S. Marucci², D. Pastori², P. Pignatelli² | ¹Department of General Surgery and Surgical Specialty, Sapienza University of Roma; ²Department of Clinical Internal, Anesthesiological and Cardiovascular Sciences, Sapienza University of Roma, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.306

  656

  PDF: 27

• CO093 | PROGNOSTIC ROLE OF ANTIPLATELET ANTIBODY TESTING IN IMMUNE THROMBOCYTOPENIA G. Maraziti, C. Schiavone, A. Fiaccadori, A. Mezzasoma, C. Becattini | Internal and Emergency Medicine - Stroke Unit, S. Maria della Misericordia Hospital – University of Perugia, Perugia, Italy

  Giorgio Maraziti

  26-10-2026

  https://doi.org/10.4081/btvb.2026.795

  22

  PDF: 9

• CO001 | DERIVATION AND VALIDATION OF THE BLEEPE SCORE FOR RISK STRATIFICATION OF MAJOR BLEEDING IN PATIENTS WITH ACUTE PULMONARY EMBOLISM M. Vedovati¹, L. Cimini¹, V. Valeriano², I. Montenovo¹, A. Murgia³, L. Pierpaoli⁴, G. Tratar⁵, S. Zaccaroni⁶, A. Bongarzoni⁷, A. Vinci¹, A. Mavri⁵, L. Martinelli⁸, G. Pepe⁹, S. Cozzio¹⁰, C. Becattini¹ | ¹University of Perugia, Perugia, Italy; ²Sandro Pertini Hospital, Roma, Italy; ³SS. Annunziata Hospital, Sassari, Italy; ⁴S. Maria delle Croci Hospital, Ravenna, Italy; ⁵University Medical Centre Ljubljana, Ljubljana, Slovenia; ⁶Maggiore Hospital, Bologna, Italy; ⁷ASST Santi Paolo e Carlo-PO San Carlo, Milano, Italy; ⁸Città di Castello Hospital, Città di Castello, Italy; ⁹Versilia Hospital, Tuscany North West Health System, Lido di Camaiore (LU), Italy; ¹⁰Rovereto Hospital, Rovereto, Italy

  Maria Cristina Vedovati

  26-10-2026

  https://doi.org/10.4081/btvb.2026.703

  71

  PDF: 11

• CO-07 | ITALIAN RESOURCE USE IN MILD HEMOPHILIA A AND TYPE 1 VON WILLEBRAND DISEASE A. Gringeri^1|2, G.C. Castaman³ | ¹Fondazione Charta, Milano, Italy; ²Centro di Sanità Solidale, Lucca, Italy; ³Centre for Bleeding Disorders and Coagulation, Careggi University Hospital, Firenze, Italy

  Alessandro Gringeri

  14-10-2026

  https://doi.org/10.4081/btvb.2026.617

  94

  PDF: 17
• 

  Diagnostic challenges in current laboratory practice at Italian Hemophilia Centers: findings from a nationwide survey

  Tiziano Martini, Alessandra Valpreda, Marina Marchetti, Alberto Catalano, Laura Contino, Raimondo De Cristofaro, Augusto Bramante Federici, Ilaria Quaglia, Rossana Rossi, Rita Carlotta Santoro, Armando Tripodi, Angelo Claudio Molinari

  12-03-2026

  https://doi.org/10.4081/btvb.2026.431

  427

  PDF: 111

  Supplementary: 51
• 

  Da la scheggia rotta usciva insieme parole e sangue: an unusual case of bleeding and the metaphor of a clinical trial

  Giovanni de Gaetano

  29-10-2024

  https://doi.org/10.4081/btvb.2024.156

  2170

  PDF: 547

  Appendix: 315
• 

  Lupus anticoagulant: a never-ending story. New insights from anti-prothrombin antibodies

  Vittorio Pengo

  28-08-2026

  https://doi.org/10.4081/btvb.2026.469

  336

  PDF: 203

• PO13 | Monitoring of anti-factor XA activity levels in patients treated with direct oral anticoagulants and concomitant tyrosine kinase inhibitors agents: a monocentric experience E. Santacroce^1,2, C. Santoro¹, E. Baldacci¹, S. Ligia¹, R. Mormile¹, M. Biglietto¹, M. Totaro¹, F. R. Mauro¹, M. Breccia¹, A. Chistolini¹ | ¹Department of Translational and Precision Medicine, Haematology, Sapienza University of Roma; ²Department of Clinical and Molecular Medicine, Sapienza University of Roma, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.313

  649

  PDF: 20

• CO39 | Artificial intelligence in hemophilia management: challenging the need for experts G. Sottilotta¹, D. Megalizzi¹, F. Luise² | ¹UOSD Microcitemie - Emostasi e Trombosi. Grande Ospedale Metropolitano Bianchi-Melacrino-Morelli, Reggio Calabria; ²Laboratorio Analisi, Grande Ospedale Metropolitano Bianchi-Melacrino-Morelli, Reggio Calabria, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.246

  615

  PDF: 14

• CO013 | INDICATIONS AND OUTCOMES OF OPTIONAL INFERIOR CAVA FILTERS IN CANCER-ASSOCIATED THROMBOSIS AND IN NON CANCER PATENTS WITH VENOUS THROMBOEMBOLISM B. Cosmi^1|2, A. Cannizzaro², M. Soldati², L. Borgese², S. Cavara^1|2, M. Sartori², L. Braccischi³, M. Taninokuchi Tomassoni⁴, D. Imberti⁵, V.O. Herasimchyj⁵, C. Mosconi^3|4 | ¹Angiology and Blood Coagulation Unit, Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy; ²IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy; ³Department of Medical and Surgical Sciences (DIMEC), University of Bologna, Bologna, Italy; ⁴Department of Radiology, IRCCS Azienda Ospedaliero Universitaria Di Bologna, Bologna, Italy; ⁵Department of Medicine and Surgery, University of Parma, Italy; ⁶Haemostasis and Thrombosis Center, Internal Medicine Department, Ospedale di Piacenza, Italy

  Benilde Cosmi

  26-10-2026

  https://doi.org/10.4081/btvb.2026.715

  36

  PDF: 10
• 

  Factor XI inhibitors in adjunct to antiplatelet therapy: the ultimate dual-pathway inhibition?

  Mattia Galli, C. Michael Gibson, Dominick J. Angiolillo

  03-08-2023

  https://doi.org/10.4081/btvb.2023.90

  2162

  PDF: 813

• PO161 | A REGIONAL DIGITAL NETWORK FOR THE MANAGEMENT OF ACQUIRED HEMOPHILIA A: A MODEL FOR INTEGRATED CARE M. Mattana¹, S. Raso¹, R. Tomasello¹, MF. Mansueto¹, C. Cammarata², S. Siragusa³, M. Napolitano^1|3 | ¹A.O.O.R. Villa Sofia Cervello P.O. Cervello-UOC di Ematologia per le Malattie Rare del Sangue e degli Organi Ematopoietici, Italy; ²PO Sant'Elia, Caltanissetta, Italy; ³Dipartimento di Promozione della Salute, Materno-Infantile, Medicina Interna e Specialistica di Eccellenza (ProMISE), Università degli Studi di Palermo, Italy

  Marta Mattana

  26-10-2026

  https://doi.org/10.4081/btvb.2026.977

  25

  PDF: 7

• CO-89 | FEMORAL FRACTURE SURGERY IN AN ELDERLY, FRAIL PATIENT WITH ACQUIRED HEMOPHILIA A RECEIVING EMICIZUMAB PROPHYLAXIS: A CASE REPORT C. Simion^1|2, E. Zanon^1|2, B. Stocco^1|2, F. Sartorello¹, C. Bulato¹, G. Saggiorato¹, P. Simioni^1|2 | ¹First Chair of Internal Medicine and Thrombotic and Haemorrhagic Diseases Unit, Department of Medicine, Padova University Hospital, Italy; ²Hemophilia Center, Padova University Hospital, Italy

  Chiara Simion

  14-10-2026

  https://doi.org/10.4081/btvb.2026.699

  42

  PDF: 19
• 

  The metaphor of Ukrainian science "bleeding"

  Gaetano Torlone

  04-04-2023

  https://doi.org/10.4081/btvb.2023.73

  789

  PDF: 361

• PO140 | HISTORY OF FALLS IN PATIENTS WITH ATRIAL FIBRILLATION: A SYSTEMATIC REVIEW AND META-ANALYSIS A.P. Speziale¹, G. Buoninfante¹, A. Ronca^2|4, B. Corica³, V. Trapani¹, M. Moretti¹, G. Annecchini¹, R. Cangemi¹, V. Raparelli¹, M. Proietti^2|4, S. Basili¹, G.F. Romiti⁵ | ¹Department of Translational and Precision Medicine, Sapienza University of Roma, Roma, Italy; ²Department of Clinical Sciences and Community Health, University of Milano, Milano, Italy; ³University of Modena and Reggio Emilia, Modena, Italy; ⁴Division of Subacute Care, IRCCS Istituti Clinici Scientifici Maugeri, Milano, Italy; ⁵Department of Wellbeing, Health and Environmental Sustainability, Sapienza University of Roma, Rieti, Italy

  Angela Pia Speziale

  26-10-2026

  https://doi.org/10.4081/btvb.2026.956

  25

  PDF: 7

• PO115 | AL AMYLOIDOSIS IN A PATIENT WITH SEVERE HEMOPHILIA A AND INHIBITORS WHO HAD A MONOZYGOTIC TWIN: SAME GENES, DIFFERENT OUTCOMES M. Biglietto, S. Sorella, S. Ligia, C. Andriola, R. Mormile, E. Baldacci, A. Chistolini, C. Santoro | Sapienza, University of Rome, Italy

  Mario Biglietto

  26-10-2026

  https://doi.org/10.4081/btvb.2026.931

  24

  PDF: 10

• PO042 | ACQUIRED HEMOPHILIA A AND ANTIPHOSPHOLIPID SYNDROME: CONCURRENCY OR OVERLAPPING? E. Galimberti¹, C. Ambaglio¹, T. Zollner¹, F. Schieppati^1|2, O.C. Cretu¹, F. Zunino¹, V. Brusegan¹, M. Marchetti^1|2, A. Falanga^1|2, L. Barcella¹ | ¹Immunohematology and Transfusion Medicine, Department of Transfusion Medicine and Hematology, ERN-EuroBloodNet - European Reference Network in Rare Hematological Diseases, ASST Papa Giovanni XXIII, Bergamo, Italy; ²School of Medicine and Surgery, University of Milano-Bicocca, Milano, Italy

  Elisa Galimberti

  26-10-2026

  https://doi.org/10.4081/btvb.2026.858

  25

  PDF: 8
• 

  Pharmacokinetics of extended half-life albumin-fused factor IX and heterogeneous F9 variants in hemophilia B: a retrospective cohort study

  Barbara Lunghi, Massimo Morfini, Silvia Linari, Dario Balestra, Alessio Branchini, Lisa Pieri, Donata Belvini, Laura Banov, Cristina Santoro, Giancarlo Castaman, Francesco Bernardi

  02-03-2026

  https://doi.org/10.4081/btvb.2026.413

  456

  PDF: 129

  Supplementary: 96
• 

  The intriguing association between cancer and congenital bleeding disorders

  Ezio Zanon

  16-12-2024

  https://doi.org/10.4081/btvb.2024.146

  846

  PDF: 189
• 

  Anticoagulation in advanced renal failure: do factor XI/XIa inhibitors represent the long-awaited shift?

  Domenico Prisco, Edoardo Biancalana, Danilo Malandrino, Irene Mattioli

  23-10-2026

  https://doi.org/10.4081/btvb.2026.595

  63

  PDF: 34

• CO04 | Direct oral anticoagulants in antiphospholipid syndrome: a single center real-life experience A. Hoxha¹, E. Campello¹, F. Ahmad², L. Spiezia¹, P. Scarinzi¹, G. Gobbo¹, S. Gavasso¹, F. Sartorello¹, C. Simion¹, E. Zanon¹, P. Simioni¹ | ¹Internal Medicine Unit, Thrombotic and Haemorrhagic Centre, Department of Medicine - DIMED; ²Department of Statistical Sciences) University of Padova, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.209

  763

  PDF: 22

• PO131 | BEYOND THE INHIBITOR TITER: THE IMPORTANCE OF EARLY COMBINED IMMUNOSUPPRESSIVE THERAPY IN THE MANAGEMENT OF ACQUIRED HEMOPHILIA A M. Luongo¹, P. Massaro¹, M. Di Mascio¹, P.G. Simeone², F. Santilli², S. Verna¹ | ¹Immunohematology Service, Asl 02 Abruzzo, Chieti, Italy; ²Department of Medicine and Aging Sciences, and Center for Advanced Studies and Technology, “G. d’Annunzio” University of Chieti–Pescara, Italy

  Myriam Luongo

  26-10-2026

  https://doi.org/10.4081/btvb.2026.947

  26

  PDF: 8

• PO085 | ACQUIRED HEMOPHILIA A IN THE SURGICAL PATIENT: DIAGNOSTIC AND THERAPEUTIC COMPLEXITY M. Luongo¹, P. Massaro¹, M. Di Mascio¹, P.G. Simeone², F. Santilli², S. Verna¹ | ¹Immunohematology Service, Asl 02 Abruzzo, Chieti, Italy; ²Department of Medicine and Aging Sciences, and Center for Advanced Studies and Technology, “G. d’Annunzio” University of Chieti–Pescara, Italy

  Myriam Luongo

  26-10-2026

  https://doi.org/10.4081/btvb.2026.901

  25

  PDF: 7
• 

  A message of science, peace and gratitude

  Giovanni de Gaetano, Chiara Cerletti

  02-12-2025

  https://doi.org/10.4081/btvb.2025.420

  942

  PDF: 98

• PO114 | A CASE OF ACQUIRED HEMOPHILIA AFTER TAVI AND CORONARY ANGIOPLASTY IN PATIENT WITH ATRIAL FIBRILLATION AND MULTIPLES CARDIOVASCULAR RISK FACTORS – THE ART AND SCIENCE OF THERAPEUTIC CONFLICT M.M. Poggi¹, C. Tamburini², M. Littera², M. Mazzetti² | ¹SOC Medicina 1, Nuovo Ospedale Prato, Prato, Italy; ²SOD Medicina Interna Interdisciplinare, Azienda Ospedaliera Universitaria Careggi, Firenze, Italy

  Matteo Maria Poggi

  26-10-2026

  https://doi.org/10.4081/btvb.2026.930

  26

  PDF: 7

• CO107 | PREGNANCY IN A YOUNG WOMAN WITH SEVERE THROMBOCYTOPENIA ASSOCIATED WITH GNE GENE MUTATION S. Bonafini¹, A. Meneguzzi¹, A. Savoia², S. Uccella³, V. Tamborrino³, S. Cesaro³, E. Bonetti³, A. Giuffrida⁴, P. Minuz¹, C. Fava¹ | ¹Dip. Medicina, Azienda Ospedaliera Universitaria Integrata Verona, Italy; ²Dip di Ingegneria per la Medicina di innovazione, Università di Verona, Italy; ³Dip. Materno-Infantile, Azienda Ospedaliera Universitaria Integrata Verona, Italy; ⁴Dip. Medicina trasfusionale, Azienda Ospedaliera Universitaria Integrata Verona, Italy

  Sara Bonafini

  26-10-2026

  https://doi.org/10.4081/btvb.2026.809

  25

  PDF: 9

• CO-03 | BEYOND CONVENTIONAL TESTING: NANOPORE LONG-READ SEQUENCING FOR RECURRENT F8 INVERSIONS IN HEMOPHILIA A A. Taiani^1|2, F. Riccardi¹, L. Cozzuto⁴, A. Delgado⁴, S. Busciglio^1|2, G. Quintavalle¹, A. Matichecchia¹, I. Tassoni¹, B.M. Roccon¹, I. R. Cannizzaro², A. Luberto², J. Ponomarenko⁴, A. Percesepe³, V. Barili², A. Coppola¹ | ¹Regional Hub Center for Hemophilia and Congenital Bleeding Disorders, University Hospital of Parma, Italy; ²Medical Genetics, Department of Medicine and Surgery, University of Parma, Italy; ³Medical Genetics, University Hospital of Parma, Italy; ⁴Centre Genomic Regulation, CRG, Barcelona, Spain

  Antonietta Taiani

  14-10-2026

  https://doi.org/10.4081/btvb.2026.613

  93

  PDF: 15
• 

  Clinical characteristics, prescription patterns and clinical outcomes of patients with extended therapy with direct oral anticoagulants for unprovoked venous thromboembolism Insights from the RIETE Registry

  Alicia Lorenzo, Carmine Siniscalchi, Silvia Natalia Morales, Teresa Sancho, Reina Valle, Aida Gil-Diaz, Parham Sadeghipour, Patricia Sigüenza, Manuel Monreal, the RIETE Investigators

  28-08-2026

  https://doi.org/10.4081/btvb.2026.403

  1573

  PDF: 139

  SUPPLEMENTARY FILES: 100

  APPENDIX: 120
• 

  OC04 | DIRECT ORAL ANTICOAGULANTS PROVIDE EFFECTIVE THROMBOPROPHYLAXIS IN NEWLY DIAGNOSED MYELOMA: REAL WORLD FINDINGS FROM THE ATOMM STUDY T. Bull¹, Heamstar Collaborators², W. Wilson³, E. Ganendra⁴, M. Thomas⁵, R. Alikhan⁶, M. Karanth¹, M. Camilleri⁷ | ¹West Suffolk Hospital NHS Foundation Trust, UK; ²Haematology Specialty Training Audit and Research HaemSTAR Network, UK; ³University College London Clinical Trial Centre, UK; ⁴North West Anglia NHS Foundation Trust, UK; ⁵University College London Hospitals, UK; ⁶Cardiff and Vale University Health Board, Wales, UK; ⁷Cambridge University Hospitals NHS Foundation Trust, UK

  ICTHIC 2026

  16-04-2026

  https://doi.org/10.4081/btvb.2026.488

  628

  PDF: 135
• 

  At the age of three

  Giovanni de Gaetano, Chiara Cerletti

  16-12-2024

  https://doi.org/10.4081/btvb.2024.166

  967

  PDF: 221