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Bleeding, Thrombosis and Vascular Biology

Editor-in-Chief: Giovanni de Gaetano, Italy | eISSN: 2785-5309

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  • Thrombosis and hemostasis at the University of Padua: a reappraisal on the occasion of its 800th year of history

    Paolo Simioni, Vittorio Pengo, Paolo Prandoni
    07-11-2022
    https://doi.org/10.4081/btvb.2022.52
    2830
    PDF: 467
  • The landscape of rare coagulation factor deficiency management in Italy: a national hemophilia center survey

    Silvia Linari, Renato Marino, Marzia Leotta, Antonio Coppola, Patrizia Di Gregorio, Augusto Bramante Federici, Flora Peyvandi, Cristina Santoro, Ezio Zanon, Rita Carlotta Santoro
    05-11-2025
    https://doi.org/10.4081/btvb.2025.369
    1375
    PDF: 222
    HTML: 140
    Appendix: 121
  • Diagnostic and management practices for inherited fibrinogen disorders: a nationwide survey of Italian Hemophilia Treatment Centers

    Renato Marino, Silvia Linari, Marzia Leotta, Antonio Coppola, Chiara Biasoli, Maria Elisa Mancuso, Flora Peyvandi, Cristina Santoro, Ezio Zanon, Rita Carlotta Santoro
    02-12-2025
    https://doi.org/10.4081/btvb.2025.372
    952
    PDF: 123
    HTML: 141
    Supplementary: 79
    Appendix: 81
  • CO02 | Hepatic fibrosis as predictor of cancer-associated thrombosis in patients with intrahepatic cholangiocarcinoma Y. Frion-Herrera1,2, C. Venturin1,3, M. Cadamuro4, J. Gasparello5, C.M. Radu1, M. Fassan5, C. Mescoli6, U. Cillo7, E. Gringeri7, G. Zanus8, L. Fabris1,3, P. Simioni1 | 1Clinical Medicine and Thrombotic and Haemorrhagic Disease Unit, and Haemophilia Center, Padua University-Hospital, Department of Medicine [DIMED], University of Padua, Italy; 2Department of Biology [DiBio], University of Padua, Italy; 3Department of Internal Medicine, Digestive Disease Section, Liver Center, Yale University, New Haven, CT, USA; 4School of Medicine and Surgery, University of Milan-Bicocca, Milan, Italy; 5Department of Pathology Ca’ Foncello Hospital, ULSS2 Marca Trevigiana, Italy; 6Pathology Unit, Padua University-Hospital, Padua, Italy; 7Hepatobiliary Surgery and Liver Transplantation Unit, Padua University-Hospital, Department of Surgery, Oncology and Gastroenterology [DISCOG], University of Padua, Italy; 8General Surgery Unit, Ca’ Foncello Hospital, ULSS2 Marca Trevigiana, Department of Surgery, Oncology and Gastroenterology [DISCOG], University of Padua, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.207
    738
    PDF: 34
  • Bioequivalence of von Willebrand factor-containing concentrates: implications for the choice in patients with von Willebrand disease. A position paper from the Italian Association of Hemophilia Centers

    Ezio Zanon, Giancarlo Castaman, Augusto Bramante Federici, Maria Elisa Mancuso, Gianfranco Pasut, Alberto Tosetto, Angiola Rocino, Rita Carlotta Santoro
    26-01-2026
    https://doi.org/10.4081/btvb.2026.415
    1324
    PDF: 351
    HTML: 171
  • Expanding the genetic landscape of hereditary thrombophilia: classical defects, novel variants, and genomic perspectives. A narrative review

    Chiara Simion, Elena Campello, Walter Ageno, Paolo Simioni
    28-08-2026
    https://doi.org/10.4081/btvb.2026.427
    1247
    PDF: 162
    SUPPLEMENTARY FILES: 115
  • CO097 | IMPACT OF THE 2023 ACR/EULAR ANTIPHOSPHOLIPID SYNDROME CRITERIA IN 1200 WOMEN WITH PRIOR OBSTETRIC ANTIPHOSPHOLIPID SYNDROME J. Alijotas-Reig1|2|3, E. Esteve-Valverde4, L. Saez-Comet5, A. Anunciacion-Llunell3, R. Ferrer-Oliveras6, E. Lefkou7, A. Mekinian8, C. Belizna9, A. Hoxha10, A. Tincani11, L. Marozio12, G. Espinosa13, S. de Carolis14, S. Udry15, J.O. Latino15, E. Llurba16, C.B. Chighizola17|18, M. Gerosa19, V. Pengo20, K. Lundelin21, P. Rovere-Querini22, V. Canti22, K. Mayer-Pickel23, T. Reshetnyak24, S. Tabacco25, L. Stojanovich26, B.A. Gonçalves27, S. Morales-Perez1, F. Miro-Mur3 | 1Department of Medicine, Universitat Autonoma de Barcelona, Spain; 2Systemic Autoimmune Disease Unit, Department of Internal Medicine, Vall d’Hebron University Hospital, Spain; 3Systemic Autoimmune Diseases Research Unit, Vall d’Hebron Institut de Recerca, Barcelona, Spain; 4Systemic Autoimmune Diseases Unit, Department of Internal Medicine, Hospital Sant Camil, Consorci Sanitari del Garraf, Barcelona, Spain; 5Department of Internal Medicine, Hospital Universitario Miguel Servet, Zaragoza, Spain; 6Obstetrics Department, High-Risk Unit, Hospital Universitario Quironsalud, Barcelona, Spain; 7Haematology Unit, Hippokration Hospital of Thessaloniki, Greece; 8AP-HP, Hopital Saint-Antoine, Service de Medecine Interne and Inflammation-Immunopathology-Biotherapy Department (DHU i2B), Sorbonne Universites, Paris, France; 9Vascular and Coagulation Department, University Hospital Angers, Angers, France; 10Internal Medicine Unit, Thrombotic and Bleeding Disorder Center, University of Padua, Padova, Italy; 11Department of Clinical and Experimental Sciences, University of Brescia, Spedali Civili, Brescia, Italy; 12Department of Obstetrics and Gynaecology, Universita di Torino, Torino, Italy; 13Systemic Autoimmune Diseases Service, Hospital Clínic, Universitat de Barcelona, Barcelona, Spain; 14Department of Gynaecology, Gemelli Hospital, Catholic University, Roma, Italy; 15Autoimmune, Thrombophilic Diseases and Pregnancy Division, Dr. Carlos G. Durand Hospital, Buenos Aires, Argentina; 16Obstetrics and Gynaecology Department, High-Risk Unit, University Hospital de la Santa Creu i Sant Pau, Barcelona, Spain; 17Department of Clinical Science and Community Health, University of Milano, Milano, Italy; 18Unit of Pediatric Rheumatology, ASST G. Pini-CTO, Milano, Italy; 19Division of Rheumatology, Department of Clinical Sciences and Community Health, University of Milano, Milano, Italy; 20Cardiology Unit, Department of Cardiac, Thoracic and Vascular Sciences, University of Padua, Padova, Italy; 21Department of Pediatrics, Faculty of Medicine, University of Turku, Turku, Finland; 22Internal Medicine and Division of Immunology, Transplantation and Infectious Diseases, IRCCS Ospedale San Raffaele, Milano, Italy; 23Department of Obstetrics, Medical University of Graz, Graz, Austria; 24Department of Systemic Rheumatic Disease, V. A. Nasonova Research Institute of Rheumatology, Moscow, Russia; 25Department of Gynecology, Obstetrics and Urology, Sapienza University of Roma, Roma, Italy; 26University Medical Center, University of Belgrade, Belgrade, Serbia; 27Department of Internal Medicine, Hospital Sant Joan Despí Moises-Broggi, Barcelona, Spain

    Ariela Hoxha
    26-10-2026
    https://doi.org/10.4081/btvb.2026.799
    86
    PDF: 25
  • Combined oral contraceptives and the risk of venous thromboembolism carriers of antithrombin, protein C or S deficiency: Sub-analysis of a prospective cohort study

    Daniela Tormene, Elena Campello, Chiara Simion, Anna Poretto, Paolo Prandoni, Paolo Simioni
    03-11-2022
    https://doi.org/10.4081/btvb.2022.42
    1600
    PDF: 501
  • PO03 | HEPATIC FIBROSIS–DRIVEN TISSUE FACTOR EXPRESSION BY MALIGNANT CHOLANGIOCYTES IS ASSOCIATED WITH CANCER-ASSOCIATED THROMBOSIS AND POOR SURVIVAL IN INTRAHEPATIC CHOLANGIOCARCINOMA L. Fabris1|2|3, Y. Frión-Herrera1, C. Venturin1|3, M. Cadamuro4, J. Gasparello5, C. M. Radu1|2, M. Fassan1|5, C. Mescoli6, U. Cillo7|8, E. Gringeri7|8, G. Zanus7|9, E. Campello1|2, M. Strazzabosco3, P. Simioni1|2 | 1Department of Medicine, University of Padua; 2Clinical Medicine 1 and Thrombotic and Haemorrhagic Disease Unit, and Haemophilia Center, Padua University-Hospital; 3Department of Internal Medicine, Digestive Disease Section, Liver Center, Yale University, New Haven, CT, USA; 4School of Medicine and Surgery, University of Milan-Bicocca, Milan, Italy; 5Pathology Unit, Ca' Foncello Hospital, ULSS2 Marca Trevigiana, Treviso; 6Pathology Unit, Padua University-Hospital; 7Department of Surgery, Oncology and Gastroenterology, University of Padua; 8Hepatobiliary Surgery and Liver Transplantation Unit, Padua University-Hospital; 9General Surgery Unit, Ca' Foncello Hospital, ULSS2 Marca Trevigiana, Treviso, Italy

    ICTHIC 2026
    16-04-2026
    https://doi.org/10.4081/btvb.2026.499
    535
    PDF: 105
  • Diagnosis and management of abnormal uterine bleeding in adolescence An expert Consensus Statement of SIGO (Italian Society of Gynecology and Obstetrics) and SISET (Italian Society for the Study of Hemostasis and Thrombosis)

    Roberto Mario Santi, Annamaria Fulghesu, Ezio Zanon, Erica De Candia, Elvira Grandone, Giancarlo Di Renzo, Claudia Succu, Valentina Tosto, Vincenzina Bruni, Paolo Gresele
    08-05-2024
    https://doi.org/10.4081/btvb.2024.106
    2885
    PDF: 749
  • Comparison among three different bleeding scores and the thrombin generation assay to assess the different hemorrhagic phenotypes in patients with FVII deficiency

    Samantha Pasca, Cristina Santoro, Chiara Ambaglio, Marisanta Napolitano, Marta Milan, Letizia Natali, Silvia Nannizzi, Filippo Mori, Paolo Simioni, Ezio Zanon
    23-05-2022
    https://doi.org/10.4081/btvb.2022.12
    5680
    PDF: 554
  • The evolving landscape of gene therapy for congenital severe hemophilia: a 2024 state of the art

    Giovanni Di Minno, Gaia Spadarella, Ilenia Lorenza Calcaterra, Giancarlo Castaman, Paolo Simioni, Raimondo De Cristofaro, Cristina Santoro, Flora Peyvandi, Matteo Di Minno
    04-09-2024
    https://doi.org/10.4081/btvb.2024.144
    2114
    PDF: 363
    SUPPLEMENTARY MATERIAL: 221
  • Management of anticoagulation in atrial fibrillation patients in Italy: insight from the Atrial Fibrillation-Survey on Anticoagulated Patients Register (AF-START)

    Daniela Poli, Walter Ageno, Emilia Antonucci, Salvatore Bradamante, Eugenio Bucherini, Paolo Chiarugi, Antonio Chistolini, Benilde Cosmi, Anna Falanga, Antonio Insana, Domenico Lione, Rosa Maria Lombardi, Giuseppe Malcangi, Rossella Marcucci, Giuliana Martini, Lucilla Masciocco, Carmelo Paparo, Daniele Pastori, Simona Pedrini, Vittorio Pengo, Pasquale Pignatelli, Andrea Toma, Sophie Testa, Gualtiero Palareti
    27-06-2023
    https://doi.org/10.4081/btvb.2023.84
    2186
    PDF: 657
    Supplementary File: 291
  • CO085 | GENE REGULATION OF THE HYPERACTIVE FIX PADUA VARIANT VIA DCAS9-KRAB TO MODULATE THROMBOPHILIA A. Benetti1, C.M. Radu1, M. Trevisan2, C. Samà1, C. Simion1, E. Campello1, P. Simioni1 | 1First Chair of Internal Medicine and Thrombotic and Haemorrhagic Diseases Unit, Department of Medicine, Padova University Hospital, Padova, Italy; 2Department of Molecular Medicine, University of Padua, Italy

    Andrea Benetti
    26-10-2026
    https://doi.org/10.4081/btvb.2026.787
    58
    PDF: 32
  • Executive summary of the consensus-based guidance from the SISET (Italian Society for the Study of Hemostasis and Thrombosis) for the management of inferior vena cava thrombosis

    Luca Barcella, Simona Pedrini, Luca Sarti, Monia Marchetti, Claudio Sallemi, Antonella Tufano, Walter Ageno, Marco Marietta
    16-10-2026
    https://doi.org/10.4081/btvb.2026.582
    284
    PDF: 54
  • CO102 | VARIABILITY IN ANTIPHOSPHOLIPID ANTIBODY TESTING AND TREATMENT STRATEGIES IN OBSTETRIC ANTIPHOSPHOLIPID SYNDROME: RESULTS FROM THE OAPS-CARE SURVEY, ON BEHALF OF THE EUROPEAN FORUM ON ANTIPHOSPHOLIPID ANTIBODIES A. Hoxha1|2, E. Esteve-Valverde3|4, G. Gobbo1|2, F. Miró-Mur4, M. Radin5, S. De Carolis6, C. Trilla7|8|9|10, A. Tincani11|12, R. Cervera13|14, J. Alijotas-Reig3|15|16 | 1Department of Medicine - DIMED, University of Padua, Padova, Italy; 2Internal Medicine Unit, Thrombosis and Bleeding Disorder, University Hospital of Padua, Padova, Italy; 3Systemic Autoimmune Diseases Unit. Department of Internal Medicine, Hospital Sant Camil, Consorci Sanitari Alt-Penedes-Garraf, Sant Pere de Ribas, Barcelona, Spain; 4Systemic Autoimmune Disease Research Unit. Vall d'Hebron Institut de Recerca (VHIR), Barcelona, Spain; 5Center of Research of Immunopathology and Rare Diseases - Coordinating Center of Piemonte and Valle d'Aosta Network for Rare Diseases, SCDU Nephrology and Dialysis, School of Specialization of Clinical Pathology, Department of Clinical and Biological Sciences, S. Giovanni Bosco Hospital, University of Turin, Torino, Italy; 6Fondazione Policlinico Universitario A. Gemelli IRCCS, Dipartimento di Scienze per la salute della Donna e del Bambino e di Sanità Pubblica, Roma, Italy; 7Hospital de la Santa Creu i Sant Pau, Barcelona, Spain; 8Universitat Autònoma de Barcelona, Barcelona, Spain; 9Spanish Network in Maternal, Neonatal, Child and Developmental Health Research (RICORS-SAMID, RD24/0013/0001), Instituto de Salud Carlos III, 28040 Madrid, Spain; 10Women and Perinatal Health Research Group, Institut de Recerca (IR SANT PAU), Sant Quintí 77-79, 08041 Barcelona, Spain; 11Rheumatology and Clinical Immunology Unit - ERN ReCONNET, ASST Spedali Civili, Brescia, Italy; 12Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy; 13Department of Autoimmune Diseases, Hospital Clínic, University of Barcelona, Barcelona, Catalonia, Spain; 14August Pi i Sunyer Biomedical Research Institute (IDIBAPS), Barcelona, Catalonia, Spain; 15Department of Medicine. Universitat Autonoma de Barcelona, Barcelona, Spain; 16Systemic Autoimmune Disease Unit, Department of Internal Medicine, Vall d’Hebron University Hospital, Barcelona, Spain

    Ariela Hoxha
    26-10-2026
    https://doi.org/10.4081/btvb.2026.804
    92
    PDF: 22
  • CO12 | Left internal carotid artery thrombosis in a patient with antiphospholipid antibody syndrome successfully treated with eculizumab A. Hoxha1, L. Nico2, F. Viaro3, L. Fabris1, Y.F. Herrera1, M. Munari4, C. Baracchini3, F. Causin2, P. Simioni1 | 1Internal Medicine Unit, Thrombotic and Haemorrhagic Centre, Department of Medicine - DIMED, University of Padua; 2Neuradiology Unit, University Hospital of Padua; 3Stroke Unit, Neurology Department, University of Padua; 4Intensive Care Unit, University Hospital of Padua, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.216
    694
    PDF: 29
  • CO-70 | CONGENITAL AFIBRINOGENEMIA: BLEEDING PHENOTYPE, THROMBOTIC COMPLICATIONS, AND LONG-TERM MANAGEMENT IN A MULTICENTER COHORT M. Biglietto1|2, M. Presti1, R.C. Santoro3, I. Nichele4, M. Napolitano5, S. Pasca6, A. Borchiellini7, B. Pollio8, E. Zanon9, G. Barillari10, A. Poz10, S. Sorella1, S. Ligia1, R. Mormile1, E. Baldacci1, G. Castaman11, F. Peyvandi12|13, C. Santoro1 | 1Hematology, Department of Translational and Precision Medicine, Sapienza University of Rome, Italy; 2Department of Molecular Biology, Sapienza University of Rome, Italy; 3Hemostasis and Thrombosis Unit, Azienda Ospedaliera Pugliese-Ciaccio, Catanzaro, Italy; 4Hematology Unit, Azienda ULSS 8 Berica - San Bortolo Hospital, Vicenza, Italy; 5Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, University of Palermo, Italy; 6Coagulation Diseases Center, Transfusion Medicine Department - Azienda Sanitaria Universitaria Integrata del Trentino, Trento, Italy; 7Centro di Riferimento Regionale Malattie Emorragiche e Trombotiche dell'Adulto, Divisione di Ematologia, Università Città della Salute e della Scienza di Torino, Italy; 8SIMT Immunohematology and Transfusion Medicine Service, Diagnostic Department, A.O. Città della Salute e della Scienza, Torino, Italy; 9Department of Medicine, Haemophilia Centre, University Hospital of Padua, Italy; 10Center for Hemorrhagic and Thrombotic Diseases, General and University Hospital S. Maria della Misericordia, Udine, Italy; 11Centre for Bleeding Disorders and Coagulation, Careggi University Hospital, Firenze, Italy; 12IRCCS Fondazione Ca' Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Milano, Italy; 13Università degli Studi di Milano, Department of Pathophysiology and Transplantation, Milano, Italy

    Mario Biglietto
    14-10-2026
    https://doi.org/10.4081/btvb.2026.680
    63
    PDF: 26
  • CO-67 | CONGENITAL DYSFIBRINOGENEMIA: BLEEDING PHENOTYPE, THROMBOTIC COMPLICATIONS, AND LONG-TERM MANAGEMENT IN A MULTICENTER COHORT M. Biglietto1|2, M. Presti1, R.C. Santoro3, I. Nichele4, M. Napolitano5, S. Pasca6, A. Borchiellini7, B. Pollio8, E. Zanon9, G. Barillari10, A. Poz10, S. Sorella1, S. Ligia1, R. Mormile1, E. Baldacci1, G. Castaman11, F. Peyvandi12|13, C. Santoro1 | 1Hematology, Department of Translational and Precision Medicine, Sapienza University of Rome, Italy; 2Department of Molecular Biology, Sapienza University of Rome, Italy; 3Hemostasis and Thrombosis Unit, Azienda Ospedaliera Pugliese-Ciaccio, Catanzaro, Italy; 4Hematology Unit, Azienda ULSS 8 Berica - San Bortolo Hospital, Vicenza, Italy; 5Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, University of Palermo, Italy; 6Coagulation Diseases Center, Transfusion Medicine Department - Azienda Sanitaria Universitaria Integrata del Trentino, Trento, Italy; 7Centro di Riferimento Regionale Malattie Emorragiche e Trombotiche dell'Adulto, Divisione di Ematologia, Università Città della Salute e della Scienza di Torino, Italy; 8SIMT Immunohematology and Transfusion Medicine Service, Diagnostic Department, A.O. Città della Salute e della Scienza, Torino, Italy; 9Department of Medicine, Haemophilia Centre, University Hospital of Padua, Italy; 10Center for Hemorrhagic and Thrombotic Diseases, General and University Hospital S. Maria della Misericordia, Udine, Italy; 11Centre for Bleeding Disorders and Coagulation, Careggi University Hospital, Firenze, Italy; 12IRCCS Fondazione Ca' Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Milano, Italy; 13Università degli Studi di Milano, Department of Pathophysiology and Transplantation, Milano, Italy

    Mario Biglietto
    14-10-2026
    https://doi.org/10.4081/btvb.2026.677
    62
    PDF: 23
  • PO19 | Joint health status in patients with moderate hemophilia A: a cross-sectional multi-center study I.L. Calcaterra1, F. Picasso2, F. Valeri3, E. Baldacci4, M. Napolitano5, C. Guerrino1, E. Zanon6, C. Santoro4, S. Siragusa7, C. Martinoli2, M. Di Minno1 | 1Department of Clinical Medicine and Surgery, Regional Reference Centre for Coagulation Disorders, Federico II University, Naples; 2Department of Health Sciences “DISSAL”, Università di Genova; 3Regional Centre for Hemorrhagic and Thrombotic Diseases, AOU Città della Salute e della Scienza, Turin; 4Haematology, Department of Translational and Precision Medicine, Sapienza University, Roma; 5Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, University of Palermo and Haematology Unit and Rare Disorders Hospital “V. Cervello”, Palermo; 6Haemophilia Centre, General Medicine, Padua University Hospital, Padua; 7Department PROMISE, University of Palermo, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.279
    615
    PDF: 36
  • CO098 | ANTI-β2GPI AND ANTI-PS/PT ANTIBODIES, AND THEIR COMBINATION, EXERT A DISTINCT PLATELET ACTIVATION PROFILE M. Camera1|2, A. Becchetti2, M.O. Borghi3|4, M. Brambilla2, P.A. Lonati4, C. Bodio4, E. Pontara5, M.G. Cattini5, E. Bison5, M. Tonello6, N. Pozzi7, P. Meroni4, V. Pengo5 | 1Department of Pharmaceutical Sciences, University of Milano, Milano, Italy; 2Unit of Cell and Molecular Biology in Cardiovascular Diseases, Centro Cardiologico Monzino IRCCS, Milano, Italy; 3Dipartimento di Scienze Cliniche e di Comunità, Dipartimento di Eccellenza 2023-2027, University of Milano, Milano, Italy; 4IRCCS Istituto Auxologico Italiano, Milano, Italy; 5Department of Cardiac-Thoracic-Vascular Sciences and Public Health, University of Padua, Padova, Italy; 6Department of Medicine, University of Padua, Padova, Italy; 7Saint Louis University School of Medicine, St. Louis, United States

    Maria Conti
    26-10-2026
    https://doi.org/10.4081/btvb.2026.800
    71
    PDF: 28
  • CO-22 | CLINICAL FEATURES IN PATIENTS WITH NON-SEVERE HEMOPHILIA A: THE DISCOVERY SCORE PROPOSAL FOR PROPHYLAXIS PRESCRIPTION M.N.D. Di Minno1, E. Baldacci2, C. Biasoli3, A. Borchiellini4, F. Daniele5, P. Di Gregorio6, C. Gorio7, G. Malcangi8, E. Marchesini9, I. Ricca10, R. Santoro11, S. Siragusa12, M.R. Villa13, E. Zanon14, A. Tagliaferri15, A. Coppola15 | 1Hub Centre for Thrombotic and Hemorrhagic Disorders, Federico II University Hospital, Napoli, Italy; 2Haematology, University Hospital Policlinico Umberto I, Roma, Italy; 3Interdepartmental Simple Structure for the Management of Hemorrhagic and Thromboembolic Diseases, M. Bufalini Hospital, Cesena, Italy; 4Regional Centre for Hemorrhagic and Thrombotic Diseases, AOU Città della Salute e della Scienza, Torino, Italy; 5Haemostasis and Thrombosis Service, Ospedale Civile dell'Annunziata, Cosenza, Italy; 6Transfusion Medicine Department, "SS. Annunziata" Hospital, Chieti, Italy; 7Pediatric Onco-Hematology Unit, Children's Hospital, ASST-Spedali Civili, Brescia, Italy; 8Haemophilia and Thrombosis Center, University Hospital Policlinico-Giovanni XXIII, Bari, Italy; 9Hemophilia Centre, SC Vascular and Emergency Department, University of Perugia, Italy; 10Centro Emofilia, Città della Salute e della Scienza, Torino, Italy; 11Hemostasis and Thrombosis Unit, Azienda Ospedaliero Universitaria Dulbecco, Catanzaro, Italy; 12Centro di Riferimento Regionale per le Emocoagulopatie Congenite, Palermo, Italy; 13Hematology Unit, Ospedale Santa Maria di Loreto, Napoli, Italy; 14Hemophilia and Thrombosis Center, University Hospital of Padua, Italy; 15Hemophilia and Thrombosis Center, Azienda Ospedaliera di Parma, Italy

    Matteo Di Minno
    14-10-2026
    https://doi.org/10.4081/btvb.2026.632
    82
    PDF: 26
  • CO012 | LONG-TERM RISK OF RECURRENT VENOUS THROMBOEMBOLISM IN ADULT PATIENTS WITH ACTIVE CANCER AND FIRST CATHETER-RELATED UPPER EXTREMITY DEEP VEIN THROMBOSIS AFTER DISCONTINUATION OF ANTICOAGULANT TREATMENTS AND LINE REMOVAL: A RETROSPECTIVE MULTI-CENTER COHORT STUDY – CANCER-CRT STUDY L. Girardi1|2, W. Ageno3, L. Bertù1, C. Lodigiani4, L.A. Ciuffini4, M.C. Vedovati5, C. Becattini5, A. Sammarco6, G. Camporese6, G. Cuni1|7, C. Ambaglio7, M.P. Donadini1 | 1Research Center on Thromboembolic Diseases and Antithrombotic Treatment, Department of Medicine and Surgery, University of Insubria, Varese, Italy; 2Department of Medicine, The Ottawa Hospital Research Institute, University of Ottawa, Ontario, Canada; 3Department of Medicine, University of Padua, Padova, Italy; 4Center for Thrombosis and Hemorrhagic Diseases, IRCCS Humanitas Research Hospital, Rozzano, Milano, Italy; 5Internal and Cardiovascular Medicine-Stroke Unit, University of Perugia, Perugia, Italy; 6Clinica Medica 1, Department of Medicine, DIMED, Padova University Hospital, Padova, Italy; 7Immunohematology and Transfusion Medicine, Department of Transfusion Medicine and Hematology, ASST Papa Giovanni XXIII, Bergamo, Italy

    Laura Girardi
    26-10-2026
    https://doi.org/10.4081/btvb.2026.714
    148
    PDF: 32
  • CO27 | Intracerebral hemorrhage in hemophilia A and B: a 10-year prospective multicenter study in Italy (2012–2022) E. Zanon1, A. Napolitano1, A. Porreca2, F. Demartis3, A. Coppola4, C. Santoro5, I. Cantori6, A. C. Molinari7, C. Biasioli8, M. Luciani9, G. Sottilotta10, B. Pollio11, A. Borchiellini12, A. Tosetto13, P. Flora14, P. Simioni1 | 1Haemophilia Center, First Chair of Internal Medicine, Department of Medicine, University-Hospital of Padua Medical School, Padua; 2Department of Human Sciences and Promotion of the Quality of Life, Unit of Clinical and Molecular Epidemiology IRCCS San Raffaele Roma Open University, Roma; Unit of Clinical and Molecular Epidemiology IRCCS San Raffaele, Roma; 3Centre for Bleeding Disorders, Careggi University Hospital of Firenze; 4Azienda Ospedaliero Universitaria di Parma; 5Hematology Division, Umberto I University Hospital of Roma; 6Haemophilia Center, Department of Transfusion Medicine, Hospital of Macerata; 7IRCCS Istituto Giannina Gaslini, Genova; 8Haemophilia and Transfusion Centre, Bufalini Hospital, Cesena; 9Children’s Hospital Bambino Gesù, Roma; 10Haemophilia Center, Department of Onco-Hematology and Radioterapy, Hospital of Reggio Calabria; 11Haemophilia Pediatric Center, Transfusion Medicine, City of Health and Science of Turin; 12City of Health and Science of Turin; 13Hemorrhagic and Thrombotic Diseases Unit, S. Bortolo Hospital of Vicenza; 14RCCS Foundation Ca’ Granda Maggiore Policlinico Hospital, Milan, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.233
    712
    PDF: 42
  • PO061 | LONG-TERM HEADACHE IMPROVEMENT WITH VITAMIN K ANTAGONISTS IN PRIMARY AND SECONDARY ANTIPHOSPHOLIPID SYNDROME: 2-YEAR OBSERVATIONAL COHORT A. Hoxha1|2, C. Belizna3, E. Esteve-Valverde4, A. Prundean5, A. Godon6, G. Gobbo1|2, A. Anunciación-Llunell7|8|9, R. Ferrer-Oliveras10, J.O. Latino11, S. Udry11, J. Alijotas-Reig7|8|9 | 1Department of Medicine, University of Padua, Padova, Italy; 2Internal Medicine Unit, Thrombosis and Bleeding Disorder Center, University Hospital of Padua, Padova, Italy; 3Vascular and Coagulation Department, University Hospital Angers, Angers, France; 4Systemic Autoimmune Diseases Unit, Department of Internal Medicine, Hospital Sant Camil, Consorci Sanitari del Garraf, Barcelona, Spain; 5University of Angers, Inserm, CNRS, MITOVASC, SFR ICAT, Angers, France; 6Centre Hospitalier Universitaire Angers, Institut National de la Santé et de la Recherche Médicale, Centre National de la Recherche Scientifique, Centre de Recherche en Cancérologie et Immunologie Intégrée Nantes Angers, Laboratoire d'Hématologie, Université d'Angers, Nantes Université, Angers, France; 7Department of Medicine, Universitat Autònoma de Barcelona, Spain; 8Systemic Autoimmune Disease Unit, Department of Internal Medicine, Vall d'Hebron University Hospital, Spain; 9Systemic Autoimmune Diseases Research Unit, Vall d'Hebron Institut de Recerca, Barcelona, Spain; 10Obstetrics Department, High-Risk Unit, Hospital Universitario Quirónsalud, Barcelona, Spain; 11Autoimmune, Thrombophilic Diseases and Pregnancy Division, Dr. Carlos G. Durand Hospital, Buenos Aires, Argentina

    Ariela Hoxha
    26-10-2026
    https://doi.org/10.4081/btvb.2026.877
    50
    PDF: 25
  • PO25 | EVOLUTION OF ANTICOAGULANT STRATEGIES AND CLINICAL OUTCOMES IN CANCER-ASSOCIATED THROMBOSIS: A LONGITUDINAL ANALYSIS OF THE START2 REGISTRY ONCO-VTE M. Marchetti1|2, T. Zollner1|2, OC. Cretu1|2, A. Chistolini3, R. Pancani4, L. Puccetti5, P. Sivera6, W. Ageno7, G. Elmi8, V. Fregoni9, V. Tonelli10, E. Antonucci11, D. Poli11|12, A. Falanga1|2, L. Barcella1|2 | 1Hemostasis & Thrombosis Center, Department of Transfusion Medicine, Papa Giovanni XXIII Hospital, Bergamo Italy; 2ERN EuroBloodNet; 3Hematology Unit, Department of Translational and Precision Medicine, Sapienza University of Rome, Rome, Italy; 4Pulmonary Unit, Hospital of Siena, University of Siena, Siena, Italy; 5Hemostasis and Thrombosis Unit, Hospital of Siena, University of Siena, Siena, Italy; 6Haematology Unit, Ordine Mauriziano Hospital, Turin, Italy; 7Department of Medicine, University of Padua, Padua, Italy; 8Department of Medicine, Maggiore Hospital, Bologna, Italy; 9Department of Medicine, Sondalo Hospital, Sondalo, Italy; 10Angiology Unit, Sant'Eugenio Hospital, Rome, Italy; 11Arianna Anticoagulazione Foundation, Bologna, Italy; 12Department of Critical Care Medicine, Thrombosis Centre, Azienda Ospedaliera Universitaria Careggi, Firenze, Italy

    ICTHIC 2026
    16-04-2026
    https://doi.org/10.4081/btvb.2026.520
    452
    PDF: 97
  • PO029 | IMPACT OF HEPATOCELLULAR CARCINOMA ON CIRCULATING RETICULATED PLATELETS IN PATIENTS WITH AND WITHOUT LIVER CIRRHOSIS S. Toffanin1, P. Guerra2, B. Serena1, C. Bulato1, A. Montagna1, C.M. Radu1, A. Bonaldo2, S. Cagnin2, C. Soldà3, M.D. Rizzato3, S. Lonardi3, F. Bergamo3, A. Zanetto4, E. Pinto4, M. Senzolo4, S. Montagnese2, E. Campello1, A. Martini2, P. Simioni1 | 1Thrombotic and Hemorrhagic Diseases Unit, General Internal Medicine, Department of Medicine, University of Padua, Padova, Italy; 2Internal Medicine and Hepatology Unit, Department of Medicine, University of Padua, Padova, Italy; 3Department of Oncology, Veneto Institute of Oncology IOV-IRCCS, Padova, Italy; 4Oncology, and Gastroenterology Unit, Department of Surgery, University of Padua, Padova, Italy

    Serena Toffanin
    26-10-2026
    https://doi.org/10.4081/btvb.2026.845
    50
    PDF: 26
  • CO30 | Joint prosthetic surgery in patients with hemophilia A: clinical-functional outcomes and quality of life E. Zanon1, A. Napolitano1, A. Berizzi2, P. Simioni1 | 1Haemophilia Center, First Chair of Internal Medicine, Department of Medicine, University-Hospital of Padua Medical School, Padua; 2Orthopedics and Traumatology Unit, University-Hospital of Padua Medical School, Padua, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.236
    708
    PDF: 42
  • Rationale and design of a study on D-dimer use to stratify patients after a first unprovoked venous thromboembolism for their risk of recurrence: extended low-dose Apixaban given only to patients with positive D-dimer results The Apidulcis study

    Gualtiero Palareti, Paolo Prandoni, Cristina Legnani, Emilia Antonucci, Serena Zorzi, Alberto Tosetto, Lorenza Bertù, Sophie Testa, Vittorio Pengo, Walter Ageno, Ida Martinelli, Benilde Cosmi, Eugenio Bucherini, Daniela Poli
    22-03-2022
    https://doi.org/10.4081/btvb.2022.10
    1910
    PDF: 588
    APPENDIX: 145
  • CO015 | EVOLUTION OF ANTICOAGULANT THERAPY FOR CANCER-ASSOCIATED THROMBOSIS: THE START2 REGISTRY ONCO-VTE LONGITUDINAL STUDY M. Marchetti1|2, T. Zollner1|2, O.C. Cretu1|2, A. Chistolini3, R. Pancani4, L. Puccetti5, P. Sivera6, W. Ageno7, G. Elmi8, V. Fregoni9, V. Tonelli10, E. Antonucci11, D. Poli11|12, A. Falanga1|2, L. Barcella1|2 | 1Hemostasis & Thrombosis Center, Department of Transfusion Medicine, Papa Giovanni XXIII Hospital, Bergamo, Italy; 2ERN EuroBloodNet; 3Hematology Unit, Department of Translational and Precision Medicine, Sapienza University of Roma, Roma, Italy; 4Pulmonary Unit, Hospital of Siena, University of Siena, Siena, Italy; 5Hemostasis and Thrombosis Unit, Hospital of Siena, University of Siena, Siena, Italy; 6Haematology Unit, Ordine Mauriziano Hospital, Torino, Italy; 7Department of Medicine, University of Padua, Padova, Italy; 8Department of Medicine, Maggiore Hospital, Bologna, Italy; 9Department of Medicine, Sondalo Hospital, Sondalo, Italy; 10Angiology Unit, Sant'Eugenio Hospital, Roma, Italy; 11Arianna Anticoagulazione Foundation, Bologna, Italy; 12Department of Critical Care Medicine, Thrombosis Centre, Azienda Ospedaliera Universitaria Careggi, Firenze, Italy

    Marina Marchetti
    26-10-2026
    https://doi.org/10.4081/btvb.2026.717
    156
    PDF: 25
  • PO138 | THE START-SIAPAV-PAD REGISTRY: RATIONALE, STUDY DESIGN AND BASELINE CHARACTERISTICS OF AN ITALIAN MULTICENTRE REGISTRY E. Favaretto1, A. Visonà2, C. Amato3, F. Biscetti4|5, B. Zalunardo6, F. Ghirardini7, A. Porfidia8, M. Cini9, E. Antonucci9, W. Ageno10 | 1Angiology Unit, IRCCS azienda ospedaliero-universitaria di Bologna, Italy; 2Osp Riabilitativo di Alta Specializzazione (ORAS), Treviso, Italy; 3Angiology Unit, University of Palermo, Italy; 4Dep of Translational Medicine and Surgery, Catholic University of the Sacred Heart, Roma, Italy; 5UOC of Cardiovascular Internal Medicine, A. Gemelli, Roma, Italy; 6Angiology Unit, Azienda ULSS 2 Marca Trevigiana, Castelfranco Veneto, Treviso, Italy; 7Angiology Unit, Azienda ULSS 1 Dolomiti, Belluno, Italy; 8Dep of Geriatric, Orthopedic, and Rheumatologic Sciences, A. Gemelli IRCCS University Hospital Foundation, Roma, Italy; 9Fondazione Arianna Anticoagulazione, Bologna, Italy; 10Dep of Medicine, University of Padua, Italy

    Elisabetta Favaretto
    26-10-2026
    https://doi.org/10.4081/btvb.2026.954
    50
    PDF: 29
  • CO17 | Clinical relevance of isolated anti-phosphatidylserine/ prothrombin antibody positivity A. Hoxha1, P. Žigon2,3, L. Katja2,3, S. Čučnik2,4, Ž. Rotar2,5, S. Gavasso1, P. Zerbinati1, G. Gobbo1, P. Simioni1 | 1University of Padua, Internal Medicine Unit, Thrombotic and Hemorrhagic Centre, Department of Medicine-DIMED, Padua, Italy; 2University Medical Centre Ljubljana, Department of Rheumatology, Ljubljana, Slovenia; 3University of Primorska, Faculty of Mathematics, Natural Sciences and Information Technologies, Koper, Slovenia; 4University of Ljubljana, Faculty of Pharmacy, Ljubljana, Slovenia; 5University of Ljubljana, Faculty of Medicine, Ljubljana, Slovenia

    22-10-2025
    https://doi.org/10.4081/btvb.2025.221
    653
    PDF: 30
  • PO074 | DEVELOPMENT OF INNOVATIVE LONG-ACTING FACTOR IX AND FACTOR X VARIANTS VIA CONDITIONAL ALBUMIN FUSION A. Martucci1, R. Tarantino1, K.H. Aaen2, M. Pinotti1, J.T. Andersen2, A. Branchini1 | 1Department of Life Sciences and Biotechnology, University of Ferrara, Ferrara, Italy; 2Institute of Clinical Medicine, Department of Pharmacology, University of Oslo, Oslo, Norway

    Alessandro Martucci
    26-10-2026
    https://doi.org/10.4081/btvb.2026.890
    75
    PDF: 20
  • PO06 | Extracellular vesicles profiles in patients with porto-sinusoidal vascular disease S. Toffanin1, E. Campello1, A. Zanetto2, C. M. Radu1, E. Pinto2, K. Fernande2, C. Bulato1, B. Serena1, L. Spiezia1, P. Burra2, M. Senzolo2, P. Simioni1 | 1First Chair of Internal Medicine, Department of Medicine, University Hospital of Padua Medical School, Padua; 2Department of Surgery Oncology and Gastroenterology, Gastroenterology and Multivisceral Transplant Unit, University Hospital of Padua, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.268
    640
    PDF: 17
  • CO24 | Extracellular vesicles profiles in patients with wild-type transthyretin amyloidosis S. Toffanin1, L. Spiezia1, C.M. Radu1, A. Napolitano1, A. Benetti1, C. Samà1, E. Campello1, L. De Michieli2, G. Sinigiani2, A. Cipriani2, P. Simioni1 | 1First Chair of Internal Medicine, Department of Medicine, University-Hospital of Padua Medical School, Padua; 2Department of Cardiac, Thoracic and Vascular Sciences and Public Health, University of Padua, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.230
    698
    PDF: 21
  • CO008 | ALLOSTATIC LOAD AND THE RISK OF ARTERIAL AND VENOUS VASCULAR EVENTS: A PROSPECTIVE ANALYSIS FROM THE MOLI-SANI STUDY T. Panzera1, A. Di Castelnuovo1, M. Bonaccio1, S. Magnacca1, A. De Curtis1, F. Bracone1, W. Ageno2, C. Cerletti1, M.B. Donati1, G. de Gaetano1, L. Iacoviello1|3, S. Costanzo1|4 | 1Research Unit of Epidemiology and Prevention, IRCCS NEUROMED, Pozzilli, Italy; 2Department of Medicine, University of Padua, Padova, Italy; 3Department of Medicine and Surgery LUM University “Giuseppe Degennaro”, Casamassima, Italy; 4Department of Medicine and Surgery, University of Insubria, Varese, Italy

    Teresa Panzera
    26-10-2026
    https://doi.org/10.4081/btvb.2026.710
    139
    PDF: 33
  • CO22 | Assessment of coagulation profiles in septic patients using viscoelastic coagulation monitoring and rotational thromboelastometry in an internal medicine setting G. Gottardi, C. Simion, D. Regazzo, C. Samà, G.P. Arcidiacono, L. Gianesello, E. Campello, P. Simioni | Department of Medicine – DIMED, University of Padua, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.228
    577
    PDF: 33
  • CO36 | Inhibitor titer at diagnosis and clinical course in acquired hemophilia A: a single-center experience C. Simion, B. Stocco, E. Dalla Porta, E. Campello, G. Furlan, L. Spiezia, G. Saggiorato, F. Sartorello, E. Zanon, P. Simioni | Department of Medicine – DIMED, University of Padua, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.243
    601
    PDF: 41
  • CO35 | Bleeding phenotype characterization in patients with congenital bleeding disorders: a multigenic approach using next generation sequencing to identify coagulation-modulating variants C. Simion, L. Gianesello, C. Bulato, A. Benetti, E. Campello, A. Giannella, G. Ceolotto, E. Zanon, L. Spiezia, P. Simioni | Department of Medicine – DIMED, University of Padua, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.242
    554
    PDF: 40
  • CO19 | Hypercoagulability in wild-type transthyretin amyloidosis: evidence from whole blood thromboelastometry A. Napolitano1, L. Spiezia1, C. Samà1, A. Benetti1, G. Sinigiani2, L. De Michieli2, A. Cipriani2, P. Simioni1 | 1First Chair of Internal Medicine, Department of Medicine, University Hospital of Padua; 2Department of Cardiothoracic and Vascular Sciences & Public Health, University Hospital of Padua, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.223
    612
    PDF: 21
  • CS06 | Patient specific iPSCs-derived sinusoidal endothelial cells for phenotypic correction of haemophilia A A. Benetti1, C.M. Radu1, C. Samà1, M. Trevisan2, C. Simion1, E. Campello1, P. Simioni1 | 1Department of Medicine - DIMED, Padua University Hospital; 2Department of Molecular Medicine, University of Padua, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.203
    741
    PDF: 28
  • CO100 | ANTIPHOSPHATIDYLSERINE–PROTHROMBIN ANTIBODIES IN ANTIPHOSPHOLIPID SYNDROME: CLINICAL ASSOCIATIONS AND DIAGNOSTIC GAPS MAPPED BY A SCOPING REVIEW H. Parikh1, G. Gobbo2|3, F. Albiero2|3, J. Dass4, E. Esteve-Valverde5|6, J. Alijotas-Reig5|7, P. Simioni2|3, A. Hoxha2|3 | 1Hemato-Oncology Clinic Vedanta, Ahmedabad, India; 2Department of Medicine (DIMED), University of Padua, Italy; 3Internal Medicine Unit and Thrombotic and Bleeding Disorder Centre, University Hospital of Padua, Padova, Italy; 4Department of Hematology, All India Institute of Medical Sciences, New Delhi, India; 5Vall d'Hebron Research Institute, Vall d'Hebron Hospital Campus, Barcelona, Spain; 6Systemic Autoimmune Diseases Unit, Department of Medicine, Hospital Sant Camil, Consorci Sanitari Alt-Penedes-Garraf, Sant Pere de Ribas, Barcelona, Spain; 7Department of Medicine, Universitat Autonoma, Barcelona, Spain

    Ariela Hoxha
    26-10-2026
    https://doi.org/10.4081/btvb.2026.802
    79
    PDF: 30
  • CO15 | Longitudinal coagulation profiling of individuals undergoing gender-affirming hormone therapy: the hyper-gender study A. Napolitano, E. Campello, A. Scala, C. Simion, C. Bulato, S. Gavasso, C. Samà, A. Benetti, S. Toffanin, G. Faggian, R. Scafa, A. Garolla, P. Simioni | First Chair of Internal Medicine, Department of Medicine, University Hospital of Padua; Unit of Andrology and Reproductive Medicine, Department of Medicine, University Hospital of Padua, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.219
    694
    PDF: 24
  • PO119 | BARTONELLA HENSELAE INFECTION ASSOCIATED WITH A MULTISYSTEMIC THROMBO-INFLAMMATORY SYNDROME IN AN IMMUNOCOMPETENT ADULT G. Gobbo1|2, M. Zacchia1|2, F. Nalesso1|3, M. Fedrigo1|4, S. Da Pozzo5, L. Frison7, F. Vianello1|6, A. Angelini1|4, P. Simioni1|2, A. Hoxha1|2 | 1Department of Medicine - DIMED, University of Padua, Italy; 2Internal Medicine Unit, Thrombotic and Bleeding Disorder Center; 3Nephrology Unit; 4Pathology Unit; 5Radiology Unit; 6Hematology Unit, University-Hospital of Padua, Italy; 7Hematology Unit, Ospedale dell’Angelo, Mestre, Italy

    Giovanni Gobbo
    26-10-2026
    https://doi.org/10.4081/btvb.2026.935
    55
    PDF: 26
  • CO086 | CLINICAL AND GENETIC CHARACTERIZATION OF A NEW FAMILY CARRYING THE “FACTOR VIII PADUA” F8 DUPLICATION E. Campello, C. Simion, F. Sartorello, D. Regazzo, C. Bulato, B. Serena, S. Toffanin, L. Spiezia, P. Simioni | Department of Medicine, University of Padova, Italy

    Elena Campello
    26-10-2026
    https://doi.org/10.4081/btvb.2026.788
    69
    PDF: 27
  • CO46 | Comparison of reticulated platelet procoagulant role in liver cirrhosis vs. fibrosis S. Toffanin1, E. Campello1, A. Zanetto2, G. Gagliardi1, A. Napolitano1, E. Stocco1, G. Gobbo1, E. Pinto2, C. M. Radu1, M. Senzolo2, L. Fabris1, P. Simioni1 | 1First Chair of Internal Medicine, Department of Medicine, University-Hospital of Padua Medical School, Padova; 2Department of Surgery Oncology and Gastroenterology, Gastroenterology and Multivisceral Transplant Unit, Padova University Hospital, Padova, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.256
    612
    PDF: 25
  • CO04 | Direct oral anticoagulants in antiphospholipid syndrome: a single center real-life experience A. Hoxha1, E. Campello1, F. Ahmad2, L. Spiezia1, P. Scarinzi1, G. Gobbo1, S. Gavasso1, F. Sartorello1, C. Simion1, E. Zanon1, P. Simioni1 | 1Internal Medicine Unit, Thrombotic and Haemorrhagic Centre, Department of Medicine - DIMED; 2Department of Statistical Sciences) University of Padova, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.209
    776
    PDF: 29
  • CO-80 | EMICIZUMAB PLASMA CONCENTRATIONS AND CLINICAL OUTCOMES IN ACQUIRED HEMOPHILIA A: A REAL-WORLD SINGLE-CENTER EXPERIENCE C. Simion1|2, E. Zanon1|2, C. Bulato1, B. Stocco1|2, F. Righetto1, F. Sartorello1, P. Simioni1|2 | 1First Chair of Internal Medicine and Thrombotic and Haemorrhagic Diseases Unit, Department of Medicine, Padova University Hospital, Italy; 2Hemophilia Center, Padova University Hospital, Italy

    Chiara Simion
    14-10-2026
    https://doi.org/10.4081/btvb.2026.690
    65
    PDF: 31
  • Aspirin or low-molecular weight heparin for thromboprophylaxis after a fracture? That is the question

    Giuseppe Camporese, Paolo Prandoni, Walter Ageno
    17-05-2023
    https://doi.org/10.4081/btvb.2023.82
    1505
    PDF: 737
  • BEST-03 | CRISPR-CAS9 CORRECTION IN SEVERE HEMOPHILIA A A. Benetti1, C.M. Radu1, M. Trevisan2, C. Samà1, C. Simion1, E. Campello1, P. Simioni1 | 1First Chair of Internal Medicine and Thrombotic and Haemorrhagic Diseases Unit, Department of Medicine, Padova University Hospital, Italy; 2Department of Molecular Medicine, University of Padua, Italy

    Andrea Benetti
    14-10-2026
    https://doi.org/10.4081/btvb.2026.603
    151
    PDF: 30
  • PO08 | Efficacy and safety of thromboprophylaxis in hospitalized hematological patients: a monocenter retrospective study S. Cordella1,2, V. Coluccio3, M. Luppi1, M. Marietta1 |  1Department of Medical and Surgical Sciences, Section of Hematology. University of Modena and Reggio Emilia, Azienda Ospedaliero-Universitaria di Modena; 2Clinical and Experimental Medicine PhD Programme, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena; 3Department of Hematology, Unità Sanitaria Locale di Modena, Italy 

    22-10-2025
    https://doi.org/10.4081/btvb.2025.270
    592
    PDF: 21
  • CO-51 | HEMOSTATIC AND CARDIOVASCULAR PROFILES IN HEMOPHILIA PATIENTS WITH AND WITHOUT ATHEROSCLEROSIS A. Napolitano, E. Zanon, L. Spiezia, G. Camporese, P. Scarinzi, F. Ahmad, G. Saggiorato, C. Bulato, S. Toffanin, S. Gavasso, F. Sartorello, C. Simion, E. Campello, P. Simioni | Hemophilia Center, University Hospital of Padua, Italy

    Angela Napolitano
    14-10-2026
    https://doi.org/10.4081/btvb.2026.661
    61
    PDF: 26
  • CO10 | Multidimensional risk assessment of venous thromboembolism: an observational study comparing the Padua prediction score, Barthel index, and quality of life in hospitalized patients A. Mameli, S. Cornacchini, P. Schirru, F. Marongiu, D. Barcellona | Hemostasis and Thrombosis Unit, University of Cagliari, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.214
    705
    PDF: 35
  • PO69 | Whole blood thrombin generation hypercoagulable profile in a patient with hemolytic crisis due to paroxysmal nocturnal hemoglobinuria: a case report A. Napolitano, L. Spiezia, C. Bulato, E. Campello, P. Simioni | First Chair of Internal Medicine, Department of Medicine, University-Hospital of Padua Medical School, Padua, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.338
    718
    PDF: 25
  • CO32 | Major surgery in patients with severe hemophilia A without inhibitors receiving prophylaxis with fitusiran E. Zanon, C. Simion, A. Napolitano, L. Spiezia, P. Simioni | Haemophilia Center, First Chair of Internal Medicine, Department of Medicine, University-Hospital of Padua Medical School, Padua, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.239
    583
    PDF: 33
  • CS01 | Elucidating the evil relationship of metabolic dysfunction–associated fatty liver disease with cardiovascular comorbidities: the complex interplay among hypercoagulability, inflammation and liver fibrosis G. Gagliardi, E. Campello, A. Napolitano, B. Stocco, C. Di Gesù, G. Gobbo, I. Condonato, M. Allegra, G. Camporese, P. Scarinzi, R. Pesavento, F. Bilora, C. Bulato, A. Benetti, C. Samà, C. Portinari, G. Antonello, C. Goffi, L. Di Daniel, A. Zambon, L. Fabris, P. Simioni | First Chair of Internal Medicine, Department of Medicine, University-Hospital of Padua Medical School, Padua, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.196
    837
    PDF: 28
  • CO-52 | CARDIOVASCULAR EVENTS AND SUBCLINICAL ATHEROSCLEROSIS IN HEMOPHILIA A AND B PATIENTS: A MULTICENTER COHORT STUDY A. Napolitano, E. Zanon, L. Spiezia, G. Camporese, P. Scarinzi, F. Ahmad, G. Saggiorato, C. Bulato, S. Toffanin, S. Gavasso, F. Sartorello, C. Simion, E. Campello, P. Simioni | Hemophilia Center, University Hospital of Padua, Italy

    Angela Napolitano
    14-10-2026
    https://doi.org/10.4081/btvb.2026.662
    62
    PDF: 27
  • Treatment of venous thromboembolism in pregnancy: findings from the RIETE Registry

    Paolo Prandoni, Franca Bilora, Raffaele Pesavento, Giorgina Salgueiro, Angeles Blanco-Molina, Raquel Lòpez-Reyes, Manuel Monreal, and the RIETE Investigators
    23-05-2022
    https://doi.org/10.4081/btvb.2022.28
    5782
    PDF: 679
    APPENDIX: 0
  • PO109 | A RARE CASE OF ANEMIA AND THROMBOCYTOPENIA E. Cosi, A. Bertomoro, I. Bertozzi, G. Bogoni, M. Zerbinati, A. Galbiati, G. Antonello, D. Lovison, P. Simioni | Department of Medicine, University of Padua, Italy

    Elisabetta Cosi
    26-10-2026
    https://doi.org/10.4081/btvb.2026.925
    56
    PDF: 26
  • CO-31 | WHEN NECK PAIN HIDES A SPINAL BLEED: ANTERIOR CERVICAL EPIDURAL HEMATOMA IN A CHILD WITH HEMOPHILIA B E. Dalla Porta, C. Simion, E. Zanon, B. Stocco, L. Spiezia, P. Simioni | Hemophilia Center, University Hospital of Padua, Italy

    Edoardo Dalla Porta
    14-10-2026
    https://doi.org/10.4081/btvb.2026.641
    63
    PDF: 29
  • CO21 | Viscoelastic testing in inherited bleeding disorders: a cross-sectional comparison between viscoelastic coagulation monitoring and rotational thromboelastometry C. Simion, C. Samà, C. Bulato, G. Gottardi, D. Regazzo, E. Campello, P. Simioni | Department of Medicine – DIMED, University of Padua, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.227
    662
    PDF: 27
  • The therapeutic landscape of cancer-associated splanchnic vein thrombosis

    Alessia Abenante, Filippo Catalani, Walter Ageno
    16-04-2026
    https://doi.org/10.4081/btvb.2026.458
    339
    PDF: 162
  • CO-29 | A RARE BLEEDING PRESENTATION IN MODERATE HEMOPHILIA A: PARAVESICAL HEMATOMA WITH PENOSCROTAL EXTENSION MIMICKING A UROLOGICAL EMERGENCY B. Stocco, C. Simion, E. Zanon, E. Dalla Porta, P. Simioni | Hemophilia Center, University Hospital of Padua, Italy

    Benedetta Stocco
    14-10-2026
    https://doi.org/10.4081/btvb.2026.639
    55
    PDF: 26
  • CO055 | COMPARISON OF VISCOELASTIC COAGULATION MONITOR AND ROTATIONAL THROMBOELASTOMETRY FOR HEMOSTATIC PHENOTYPING AND OUTCOME PREDICTION IN SEPSIS G. Gottardi, E. Campello, C. Simion, C. Samà, A. Benetti, C. Bulato, D. Regazzo, G.P. Arcidiacono, P. Simioni | Department of Medicine, University of Padua, Italy

    Giovanni Gottardi
    26-10-2026
    https://doi.org/10.4081/btvb.2026.757
    86
    PDF: 28
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    Angela Napolitano
    26-10-2026
    https://doi.org/10.4081/btvb.2026.894
    43
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    Maria Cristina Vedovati
    26-10-2026
    https://doi.org/10.4081/btvb.2026.739
    59
    PDF: 31
  • CO-65 | COVID-19-ASSOCIATED HYPERCOAGULABILITY IN TYPE 2B VON WILLEBRAND DISEASE: INSIGHTS FROM GLOBAL HEMOSTATIC ASSAYS I. Condonato, C. Simion, E. Zanon, P. Simioni | Hemophilia Center, University Hospital of Padua, Italy

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    14-10-2026
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  • Comment on "Apixaban vs. aspirin for stroke prevention in people with subclinical atrial fibrillation and a history of stroke or transient ischemic attack: subgroup analysis of the ARTESiA randomized controlled trial"

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Bleeding, Thrombosis and Vascular Biology

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