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Bleeding, Thrombosis and Vascular Biology

Editor-in-Chief: Giovanni de Gaetano, Italy | eISSN: 2785-5309

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  • Identifying novel biomarkers using proteomics to predict cancer-associated thrombosis

    Maria J. Fernandez Turizo, Rushad Patell, Jeffrey I. Zwicker
    16-05-2024
    https://doi.org/10.4081/btvb.2024.120
    1214
    PDF: 521
  • Descriptive analysis of patients positive for anti-phospholipid antibodies included in two Italian registries

    Vittorio Pengo, Luca Sarti, Emilia Antonucci, Stefania Di Agostino, Elisa Bison, Gentian Denas, Daniela Poli, Pier Luigi Meroni, Roberto Gerli, Antonella Radice, Gualtiero Palareti, on behalf of FIRMA group and START collaborators
    12-10-2023
    https://doi.org/10.4081/btvb.2023.92
    1057
    PDF: 318
  • Persistence of functional anti-PF4 antibodies and neutrophil activation in vaccine-induced immune thrombotic thrombocytopenia

    Eleonora Petito, Anna Maria Mezzasoma, Emanuela Falcinelli, Chiara Conti, Erica De Candia, Raimondo De Cristofaro, Silvia Sorrentino, Gian Marco Podda, Mariangela Scavone, Anna Falanga, Marina Marchetti, Luca Barcella, Stefania Basili, Lucia Stefanini, Andrea Boccatonda, Laura Contino, Patrizia Sciancalepore, Igor Florio, Egidio Imbalzano, Rossella Marcucci, Angela Rogolino, Patrizia Noris, Marta Panella, Rita Santoro, Maria Costanza Turi, Gaetano Vaudo, Rosa Curcio, Paolo Gresele
    18-11-2025
    https://doi.org/10.4081/btvb.2025.400
    464
    PDF: 67
    HTML: 43
  • PO56 | Safety of anticoagulant treatment in patients with splanchnic vein thrombosis and history of portal hypertension-related bleeding R. Talerico1, S. Pellegrino1, A. Plessier2, F.R. Ponziani3, A. Porfidia1, F. Landi1, A. Gasbarrini3, R. Pola1, F. Santopaolo3 | 1Department of Geriatric, Orthopedic, and Rheumatologic Sciences, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Roma, Italy; 2Université de Paris, AP-HP, C, DMU DIGEST, Centre de Référence des Maladies Vasculaires du Foie, FILFOIE, ERN RARE-LIVE. Centre de recherche sur l’inflammation, Inserm, Paris, France; 3Department of Medical and Surgical Sciences, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Roma, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.325
    374
    PDF: 0
  • A nitric oxide-donor pravastatin hybrid drug exerts antiplatelet and antiatherogenic activity in mice

    Stefania Momi, Giuseppe Guglielmini, Giulia Ciarroca Taranta, Elisa Giglio, Angela Monopoli, Paolo Gresele
    23-05-2022
    https://doi.org/10.4081/btvb.2022.19
    4892
    PDF: 351
  • PO88 | Bacterial lysate “lantigen B” induces proliferation of B and NK cells and the release of related cytokines M. Alfonsetti1, R. Liani1, P. Di Mattia3, M. Tredicine4, F. Papa3, Q. Niu5, M. Di Gioacchino2, F. Santilli1,3 | 1Department of Medicine and Aging, Center for Advanced Studies and Technology, University of Chieti, Italy; 2Institute for Clinical Immunotherapy and Advanced Biological Treatments, Pescara, Italy; 3Specialization School of Allergy and Clinical Immunology, G. d’Annunzio University, Chieti, Italy; 4Department of Medical, Oral, and Biotechnology Science, University G. d’Annunzio, Chieti-Pescara, Chieti, Italy; 5Department of Occupational Health, School of Public Health, Shanxi Medical University, Taiyuan, Shanxi, China

    22-10-2025
    https://doi.org/10.4081/btvb.2025.358
    477
    PDF: 0
  • https://BioRender.com/zrlk3rh

    The subtle red line between combating and resolving inflammation in the cardiovascular disease, a “silent sniper”

    Ciarán Kennedy, Luke J. Conroy, Braden Millar, Monica de Gaetano
    30-06-2025
    https://doi.org/10.4081/btvb.2025.187
    1130
    PDF: 210
  • PO32 | Effect of the sodium-glucose co-transporter-2 (SGLT2) inhibitors on platelet activation and lipid peroxidation: results of a pilot study P.G.M. Simeone1, R. Liani1, M. Alfonsetti1, B. Cancelli1, M. Frezza1, G. Raggiunti1, S. Zeeba2, F. Cipollone1, G. Renda2, F. Santilli1 | 1Department of Medicine and Aging Sciences, Center for Advanced Studies and Technology, University of Chieti; 2Department of Neuroscience, Imaging and Clinical Sciences, G. D’Annunzio University of Chieti-Pescara; 3University Cardiology Division, Heart Department, Policlinico SS Annunziata, Chieti, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.293
    383
    PDF: 0
  • PO55 | Evaluation of safety and efficacy of emicizumab prophylaxis in pediatric patients with hemophilia A – a single centre experience M.L. Tramontano, M. Coppola, S. Coppola, M. Schiavulli | UOSD Centro Regionale Pediatrico Malattie della Coagulazione, Santobono Pausilipon Children Hospital, AORN, Napoli, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.324
    361
    PDF: 0
  • Commentary on “Preventive percutaneous coronary intervention versus optimal medical therapy alone for the treatment of vulnerable atherosclerotic coronary plaques (PREVENT): a multicenter, open-label, randomized controlled trial”

    Ottavia Borghese, Claudio Vincenzoni
    26-06-2024
    https://doi.org/10.4081/btvb.2024.141
    1213
    PDF: 315
  • The night of randomized clinical trials where all patients are black: a need to estimate variability in treatment effects

    Giovanni de Gaetano, Chiara Cerletti, Licia Iacoviello, Maria Benedetta Donati
    22-03-2022
    https://doi.org/10.4081/btvb.2022.24
    2030
    PDF: 303
  • Palestinian patients associations appeal on World Hemophilia Day

    Sara Mellano
    17-04-2024
    https://doi.org/10.4081/btvb.2024.136
    552
    PDF: 168
  • Bioequivalence of von Willebrand factor-containing concentrates: implications for the choice in patients with von Willebrand disease. A position paper from the Italian Association of Hemophilia Centers

    Ezio Zanon, Giancarlo Castaman, Augusto Bramante Federici, Maria Elisa Mancuso, Gianfranco Pasut, Alberto Tosetto, Angiola Rocino, Rita Carlotta Santoro
    26-01-2026
    https://doi.org/10.4081/btvb.2026.415
    15
    PDF: 7
  • The evolution of hemostasis genetics: from monogenic disorders to complex traits. A historical perspective

    Augusto Di Castelnuovo
    01-07-2025
    https://doi.org/10.4081/btvb.2025.184
    1096
    PDF: 193
  • PO93 | Use of DOACS in heart transplantation recipients T. Marrazzo1, A. Delle Femine1, C. Amarelli2, R. Albisinni3 | 1UOC Medicina Interna e dei Trapianti, Ospedale Monaldi Azienda dei Colli, Napoli; 2UOSD CCH dei Trapianti, Ospedale Monaldi Azienda dei Colli, Napoli; 3UOC CCH Generale, Ospedale Monaldi Azienda dei Colli, Napoli, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.363
    486
    PDF: 0
  • PO75 | Prophylaxis with RFXIII: a clinical case in a pediatric patient with congenital FXIII deficiency and delayed diagnosis M.L. Tramontano, M. Coppola, S. Coppola, M. Schiavulli | UOSD Centro Regionale Pediatrico Malattie della Coagulazione. Santobono Pausilipon Children Hospital, AORN, Napoli, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.344
    396
    PDF: 0
  • PO31 | Comparative analysis of anticoagulant therapy in patients over 90 years old: vitamin K antagonists versus direct oral anticoagulants G. Sottilotta1, P. Arrigo2, S. Cuzzocrea1, D. Megalizzi1, F. Luise3 | 1UOSD Microcitemie, Emostasi e Trombosi, Grande Ospedale Metropolitano di Reggio Calabria; 2Associazione Italiana Pazienti Anticoagulati, Sezione di Reggio Calabria; 3Laboratorio Analisi. Grande Ospedale Metropolitano di Reggio Calabria, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.292
    387
    PDF: 0
  • CO04 | Direct oral anticoagulants in antiphospholipid syndrome: a single center real-life experience A. Hoxha1, E. Campello1, F. Ahmad2, L. Spiezia1, P. Scarinzi1, G. Gobbo1, S. Gavasso1, F. Sartorello1, C. Simion1, E. Zanon1, P. Simioni1 | 1Internal Medicine Unit, Thrombotic and Haemorrhagic Centre, Department of Medicine - DIMED; 2Department of Statistical Sciences) University of Padova, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.209
    503
    PDF: 0
  • A case of acquired factor XIII deficiency secondary to plasmablastic lymphoma

    Vincenzo Sammartano, Adele Santoni, Elisabetta Zappone, Paola Calzoni, Daniela Fineschi, Eleonora Franceschini, Federico Caroni, Anna Sicuranza, Monica Bocchia, Luca Puccetti
    09-03-2023
    https://doi.org/10.4081/btvb.2023.53
    958
    PDF: 418
  • PO86 | Emicizumab in patients with moderate hemophilia A and severe bleeding phenotype: single-center real-world experience A.L. Faccini, M. Biglietto, S. Sorella, E. Crisanti, M. Antonacci, R. Mormile, R. Ciciani, E. Baldacci, C. Santoro, S. Ligia | Hematology, Department of Translational and Precision Medicine Sapienza University of Roma, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.355
    510
    PDF: 0
  • CO15 | Longitudinal coagulation profiling of individuals undergoing gender-affirming hormone therapy: the hyper-gender study A. Napolitano, E. Campello, A. Scala, C. Simion, C. Bulato, S. Gavasso, C. Samà, A. Benetti, S. Toffanin, G. Faggian, R. Scafa, A. Garolla, P. Simioni | First Chair of Internal Medicine, Department of Medicine, University Hospital of Padua; Unit of Andrology and Reproductive Medicine, Department of Medicine, University Hospital of Padua, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.219
    410
    PDF: 0
  • PO64 | A silent hemorrhage in the immuno-thrombotic chaos of antiphospholipid syndrome G. Autiero, S.A. Malerba, A. Malaguti, M. Dalla Vestra, F. Presotto | Medicina Generale, Ospedale dell’Angelo, Mestre-Venezia, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.333
    389
    PDF: 0
  • PO18 | Does muscle mass matter? Appendicular lean mass as a determinant of anti-XA activity in elderly patientes B.M. Zanforlini1, V. Bernardi1, E. Campello2, E.M. Bicego1, C. Curreri1, A. Vaticano1, C. Sartori1, L. Manfron1, A. Perencin1, P. Rollo1, A. Baruffol1, L. Ruoso1, C. Simion2, C. Bulato2, P. Berto2, P. Simioni2, G. Sergi1 | 1Department of Medicine, Geriatrics Section, University of Padova; 2Haemorrhagic and Thrombotic Diseases Unit, Department of Medicine DIMED, Padova University Hospital, Padova, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.278
    383
    PDF: 0
  • Talking about assisted reproductive techniques and thromboembolic risk: everything we always wanted to know

    Giovanni Tiscia, Elvira Grandone
    13-09-2022
    https://doi.org/10.4081/btvb.2022.43
    2399
    PDF: 303
  • PO92 | Challenging management of portal vein thrombosis in a cirrhotic patient on hormone therapy after breast cancer L. Jr Valletta, C. De Luca, M. Aversano, C. Caputo, E. Cimino, P. Conca, A. Tufano, M.D. Di Minno | AOU Federico II Napoli, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.362
    406
    PDF: 0
  • CO05 | Long-term management of upper extremity catheter-related thrombosis in female patients with cancer: a retrospective cohort study Chiara Cavallaro1,2, Paolo Santini1,2, Laura Leoni3, Carolina Mosoni1,2, Silvia D’Ambrosio1,2, Francesco Mancinetti1,2, Nicola Coletta1,2, Michela Iorio1,2, Angelo Porfidia1,2, Alessandro D’Errico1,2, Rosa Talerico1,2, Roberto Pola1,2 | 1Department of Aging, Orthopedic, and Rheumatologic Sciences, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome; 2Università Cattolica del Sacro Cuore, Rome; 3Vita-Salute University, San Raffaele Hospital IRCCS, Milan, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.309
    451
    PDF: 0
  • CO31 | Immune system profiling in FVIII-treated and emicizumab-treated pediatric HA patients A. Cottonaro1, S. Akula1, B. Pollio2, I. Ricca2, T. Martini2, J. Agnelli Giacchello3, P. Sciancalepore3, R. Santi3, A. Follenzi1,3, S. Merlin1 | 1Università del Piemonte Orientale, Health Sciences, Novara; 2A.O. Città della Salute e della Scienza, SIMT Immunohematology and Transfusion Medicine Service, Diagnostic Department, Torino; 3Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo, Alessandria, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.238
    384
    PDF: 0
  • CO03 | Early discharge and home treatment of low-risk pulmonary embolism: a cohort study E. Ruggeri1, L. Vulcano1, W. Ageno2, F. Cortellaro3, M.P. Donadini3,4 | 1Scuola di Medicina, Università degli Studi dell’Insubria, Varese; 2Dipartimento di Medicina, Università degli Studi di Padova; 3Pronto Soccorso e Medicina d’Urgenza, Ospedale di Circolo, ASST Sette Laghi, Varese; 4Dipartimento di Medicina e Chirurgia, Università degli Studi dell’Insubria, Varese, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.208
    435
    PDF: 0
  • Interaction between adenosine diphosphate receptors and protein-kinase C isoforms in platelet adhesion under flow condition

    Boris Shenkman, Ivan Budnik, Yulia Einav
    16-02-2023
    https://doi.org/10.4081/btvb.2023.51
    1532
    pdf: 307
  • Ankle brachial index for the diagnosis of asymptomatic lower extremity peripheral arterial disease

    Francesco Cicconi
    05-07-2024
    https://doi.org/10.4081/btvb.2024.128
    1868
    PDF: 471
  • PO38 | Rates of hemorrhagic events and hemodialysis circuit thrombosis in patients with end-stage renal disease on hemodialytic treatment receiving a factor-XI inhibitor: a systematic review and meta-analysis D. Santagata, G. Barbui, M.P. Donadini, A. Squizzato | Department of Medicine and Surgery, Research Center on Thromboembolic Disorders and Antithrombotic Therapies, University of Insubria, Varese and Como, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.301
    387
    PDF: 0
  • CO12 | Left internal carotid artery thrombosis in a patient with antiphospholipid antibody syndrome successfully treated with eculizumab A. Hoxha1, L. Nico2, F. Viaro3, L. Fabris1, Y.F. Herrera1, M. Munari4, C. Baracchini3, F. Causin2, P. Simioni1 | 1Internal Medicine Unit, Thrombotic and Haemorrhagic Centre, Department of Medicine - DIMED, University of Padua; 2Neuradiology Unit, University Hospital of Padua; 3Stroke Unit, Neurology Department, University of Padua; 4Intensive Care Unit, University Hospital of Padua, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.216
    430
    PDF: 0
  • PO62 | Management of anticoagulation during extracorporeal circulation in a patient with APS T. Marrazzo1, C. Marra2, A. Caiazzo2, I. Mattucci2, L. Verniero3, N. Galdieri3, M.P. Ursi4, R. Albisinni5 | 1UOC Medicina Interna e dei Trapianti, Ospedale Monaldi Azienda dei Colli, Napoli; 2UOSD di Cardiochirurgia dei Trapianti, Ospedale Monaldi Azienda dei Colli, Napoli; 3UOSD Terapia Intensiva di CCH Ospedale Monaldi Azienda dei Colli, Napoli; 4UOC MECAU Ospedale CTO Azienda dei Colli, Napoli; 5UOC CCH generale Ospedale Monaldi Azienda dei Colli, Napoli, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.331
    380
    PDF: 0
  • PO90 | Acquired hemophilia A with high-titer inhibitor in a patient with cardiovascular and metabolic comorbidities M.G. Mazzone, G. Chiarelli, R. Russo, L. Valletta Jr, G. D’Errico, C. De Luca, P. Rufolo, A. Tufano, E. Cimino, P. Conca, M.N.D. Di Minno | Department of Clinical Medicine and Surgery, Federico II University of Naples, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.360
    454
    PDF: 0
  • CO30 | Joint prosthetic surgery in patients with hemophilia A: clinical-functional outcomes and quality of life E. Zanon1, A. Napolitano1, A. Berizzi2, P. Simioni1 | 1Haemophilia Center, First Chair of Internal Medicine, Department of Medicine, University-Hospital of Padua Medical School, Padua; 2Orthopedics and Traumatology Unit, University-Hospital of Padua Medical School, Padua, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.236
    415
    PDF: 0
  • Location of metastasis and complications in patients with venous thromboembolism and cancer: a systematic review

    Maria Barca-Hernando, Victor Garcia-Garcia, Luis Jara-Palomares
    16-05-2024
    https://doi.org/10.4081/btvb.2024.114
    775
    PDF: 383
  • CS06 | Patient specific iPSCs-derived sinusoidal endothelial cells for phenotypic correction of haemophilia A A. Benetti1, C.M. Radu1, C. Samà1, M. Trevisan2, C. Simion1, E. Campello1, P. Simioni1 | 1Department of Medicine - DIMED, Padua University Hospital; 2Department of Molecular Medicine, University of Padua, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.203
    443
    PDF: 0
  • Thrombosis and hemostasis at the University of Padua: a reappraisal on the occasion of its 800th year of history

    Paolo Simioni, Vittorio Pengo, Paolo Prandoni
    07-11-2022
    https://doi.org/10.4081/btvb.2022.52
    2322
    PDF: 290
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Bleeding, Thrombosis and Vascular Biology

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