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PO162 | A RARE CASE OF PLATELET DISORDER MIMICKING HEMOPHILIA A M. Shani, T. Goxhaj | Mother Theresa University Hospital, Università Nostra Signora Dell Buon Consiglio, Tirana, Albania
28PDF: 18 -
PO28 | CLINICAL IMPLICATIONS OF ANTICOAGULANT DRUG INTERACTIONS WITH TARGETED AND IMMUNE THERAPIES IN ONCOLOGY: A CONTEMPORARY RISK STRATIFICATION FRAMEWORK D. Dhami1, C. Solowiej Singh 1, M. Dhami 2 | 1Abrazo Internal Medicine Residency; 2Eastern Connecticut Hematology Oncology, Norwich, CT, USA
589PDF: 105 -
PO131 | BEYOND THE INHIBITOR TITER: THE IMPORTANCE OF EARLY COMBINED IMMUNOSUPPRESSIVE THERAPY IN THE MANAGEMENT OF ACQUIRED HEMOPHILIA A M. Luongo1, P. Massaro1, M. Di Mascio1, P.G. Simeone2, F. Santilli2, S. Verna1 | 1Immunohematology Service, Asl 02 Abruzzo, Chieti, Italy; 2Department of Medicine and Aging Sciences, and Center for Advanced Studies and Technology, “G. d’Annunzio” University of Chieti–Pescara, Italy
31PDF: 13 -
PO152 | A CASE REPORT OF HEREDITARY HEMORRHAGIC TELANGIECTASIA WITH PULMONARY ARTERIOVENOUS FISTULA M. Veneri1, R. Benedetti2, V. Della Corte2, V. Herasimchyk2, F. Giangregorio3, D. Imberti4 | 1U.O. Medicina Interna, Osp. di Piacenza, Italy; 2U.O. Medicina Interna, Centro Emostasi e Trombosi, Osp. di Piacenza, Italy; 3U.O. Medicina Interna Osp. di Castel San Giovanni, Italy; 4Department of Medicine and Surgery, University of Parma, Italy
28PDF: 15 -
PO122 | SUCCESSFUL MANAGEMENT OF THERAPEUTIC ANTICOAGULATION FOR PROVOKED VENOUS THROMBOEMBOLISM IN A PATIENT WITH FACTOR VII DEFICIENCY AND SEPTIC SHOCK S. Birocchi1, F.M. Monda1, B. Clerici1|2, M. Scavone2, R. Cabiddu1, E. Pontisso1, C. Ortelli1, M.L.G. Perego1, E. Fiorini1, L. Catarini1, A. Bortoli1, M. Manzoni1, F.M. Casanova1, A. Tripodi2|3, F. Peyvandi2|3, G.M. Podda1|2 | 1S.C. Medicina Generale 2, Ospedale San Paolo, ASST Santi Paolo e Carlo, Milano, Italy; 2Dipartimento di Scienze della Salute, Università degli Studi di Milano, Italy; 3Centro di riferimento emofilia e trombosi "Emilio Bianchi"; 4S. Birocchi and F.M. Monda contributed equally as co-first authors
56PDF: 16 -
PO161 | A REGIONAL DIGITAL NETWORK FOR THE MANAGEMENT OF ACQUIRED HEMOPHILIA A: A MODEL FOR INTEGRATED CARE M. Mattana1, S. Raso1, R. Tomasello1, MF. Mansueto1, C. Cammarata2, S. Siragusa3, M. Napolitano1|3 | 1A.O.O.R. Villa Sofia Cervello P.O. Cervello-UOC di Ematologia per le Malattie Rare del Sangue e degli Organi Ematopoietici, Italy; 2PO Sant'Elia, Caltanissetta, Italy; 3Dipartimento di Promozione della Salute, Materno-Infantile, Medicina Interna e Specialistica di Eccellenza (ProMISE), Università degli Studi di Palermo, Italy
30PDF: 14 -
PO004 | SEX-RELATED DIFFERENCES AND PREDICTORS OF MORTALITY IN MAJOR ORTHOPEDIC SURGERY: INSIGHTS FROM THE ORTHO-START REGISTRY A. de Laurenzo1, E. Antonucci2, C. Rostagno3, D. Barcellona4, D. Colaizzo1, G. di Rienzo5, F. Gorgoglione1, G. Maccagnano6, F. Marongiu2, M. Mastroianno1, M. Marzolo7, L. Mirabella6, B. Moretti8, A.M. Moretti9, A. Ostuni6, G. Palareti2, M. Margaglione6, E. Grandone1|6 | 1Fondazione I.R.C.C.S. “Casa Sollievo della Sofferenza”, S. Giovanni R. (Foggia), Italy; 2Fondazione Arianna, Bologna, Italy; 3Department of Internal and Postoperative Medicine, Careggi University Hospital, Firenze, Italy; 4Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy; 5UOC Patologia Clinica-Ospedale Altamura ASL Bari, Italy; 6University of Foggia, Policlinico Riuniti Foggia, Italy; 7Angiology Unit, Ospedale di Rovigo, Rovigo, Italy; 8School of Medicine, AOU Consorziale Policlinico, University of Bari "Aldo Moro", Italy; 9President of GISeG (Italian Group for Health and Gender), Bari, Italy
31PDF: 14 -
CO-79 | ACQUIRED FACTOR XIII DEFICIENCY: AN UNDERDIAGNOSED CAUSE OF DELAYED BLEEDING AFTER PERICARDIOCENTESIS M. Luongo1, J. Di Paolo1, G. D’Amico2, P. Massaro1, M. Di Mascio1, R. Malizia1, U. Benedetto2, S. Verna1 | 1Immunohematology Service, Asl 02 Abruzzo, Chieti, Italy; 2 Department of Cardiac Surgery, Asl 02 Abruzzo, Chieti, Italy
64PDF: 18 -
CO28 | Cognitive, adaptive abilities and behavioral symptoms in children and adolescents with hemophilia: a pilot study R. Vallone1, M. Luciani2, A. Smigliani2, M. F. Mansueto3, S. Vicari1,4, D. Menghini1 | 1Child and Adolescent Neuropsychiatry Unit, Bambino Gesù Children’s Hospital, IRCCS, Roma; 2OncoHematology Unit, Bambino Gesù Children’s Hospital, IRCCS, Roma; 3Department of Oncology U.O. Hematology AUO Policlinico, Paolo Giaccone, Palermo; 4Department of Life Science and Public Health, Università Cattolica del Sacro Cuore, Roma, Italy
680PDF: 25 -
PO064 | CONGENITAL THROMBOTIC THROMBOCYTOPENIC PURPURA: HOW TO MANAGE? - A CASE FROM REAL WORLD N. Galli1, S. Giuliano2, S. Grasso3, B. Montaruli4, D. Cilloni1, G. Giuffrida3, P. Sivera4 | 1Department of Clinical and Biological Sciences, University of Turin, Italy; 2Department of Medical Sciences, University of Turin, Italy; 3AOU Policlinico “G. Rodolico San Marco”, Catania, Italy; 4Haematology and Cellular Therapies Unit, A. O. Ordine Mauriziano di Torino, Italy
32PDF: 14 -
BEST-08 | PERIOPERATIVE MANAGEMENT OF CHILDREN WITH MILD FACTOR VII DEFICIENCY UNDERGOING SURGERY: A RETROSPECTIVE COHORT STUDY B. Borsellino1, T. Martini1, I. Ricca2, B. Pollio1 | 1Haemophilia Centre, Immune-Haematology and Transfusion Medicine, University Hospital “Città della Salute e della Scienza”, Torino, Italy; 2Transfusion Medicine, Ivrea Hospital, Ivrea, Italy
153PDF: 21 -
PO103 | THE EFFECT OF ALBUMIN ON SERUM CONCENTRATION OF DIRECT ORAL ANTICOAGULANTS: A CROSS-SECTIONAL STUDY A. Pannunzio1, E. Valeriani2, I.M. Palumbo1, V. Cammisotto3, S. Bartimoccia3, V. Castellani3, S. Marucci3, D. Pastori3, D. Menichelli3, P. Pignatelli3 | 1Dip. di Chirurgia generale, specialistica ed anestesiologia - Università degli studi di Roma La Sapienza, Italy; 2Dip. di Medicina Interna, Scienze Endocrino-metaboliche e Malattie Infettive - Università degli Studi di Roma La Sapienza, Italy; 3Dip. di Medicina e Scienze Cardiovascolari - Università degli Studi di Roma La Sapienza, Italy
42PDF: 14 -
PO073 | ANALYTICAL VARIABILITY IN FIBRINOGEN TESTING REVEALING FIBRINOGEN LONGMONT: A CASE REPORT A. Paradiso1, S. Cmet2, E. Fontanini2 | 1Dep. of Medicine, University of Udine, Udine, Italy; 2Dep. of Laboratory Medicine, Institute of Clinical Pathology, Azienda Ospedaliera Universitaria Friuli Centrale, Udine, Italy
33PDF: 18 -
CO-72 | HEREDITARY FACTOR X DEFICIENCY UNMASKED BY NECROTIZING HEMORRHAGIC PANCREATITIS: A CASE REPORT M. Leotta, A. Strangio, A. Ierardi, R.C. Santoro | Hemophilia Treatment Center AOU Dulbecco, Catanzaro, Italy
47PDF: 20 -
CO-08 | IMPLEMENTING A HUB-AND-SPOKE MODEL FOR HEMOPHILIA DIAGNOSIS AND CARE IN BURKINA FASO THROUGH TRAINING OF “HEALTH ASSISTANTS” C. Gorio1, E. Kafando2, A. Buzzi3 | 1Oncohematology Unit ASST Spedali Civili Brescia, Italy; 2Centre Hospitalier Universitaire Charles de Gaulle, Italy; 3Fondazione Paracelso ETS, Milano, Italy
97PDF: 19 -
PO81 | Direct oral anticoagulants in atypical site vein thrombosis: a single centre experience focused on cancer patients U. Mazzarelli1, A. Guida1, L. Agrelli1, M. Amato1, R. Guarrasi2, L. Santaniello2, C. Cardamone1, P. Vitale1, M. Triggiani1 | 1Centro per le Malattie Emorragiche Congenite e Malattie Trombotiche UOC Clinica Immunologica e Reumatologica AOU S. Giovanni di Dio e Ruggi d’Aragona, Salerno; 2UOC Clinica Oncologica AOU S. Giovanni di Dio e Ruggi d’Aragona, Salerno, Italy
642PDF: 27 -
PO039 | CLINICAL AND LABORATORY CHARACTERISTICS OF ACQUIRED HEMOPHILIA A: PRELIMINARY RESULTS FROM A RETROSPECTIVE OBSERVATIONAL MONOCENTRIC STUDY S. Suardi1, M. Bodini2, A.C. Giuffrida2, A. Zanzanelli3, S. Moruzzi1, L. Delfino1, F. Pizzolo1, S. Genesini2, M. Cantini2, C. Spillere1, L. Panepinto1, F. Zoccatelli1, E. Malloggi1, F. Presa1, A. Moschella1, M. Merlo1, G. Gandini2, S. Friso1, N. Martinelli1 | 1Department of Medicine, Unit of Internal Medicine B, Azienda Ospedaliera Universitaria Integrata di Verona, Italy; 2Department of Transfusion Medicine, Hemophilia Center, Azienda Ospedaliera Universitaria Integrata di Verona, Italy; 3Division of Internal Medicine, IRCCS Azienda Ospedaliero Universitaria Bologna, Italy
40PDF: 16 -
CO025 | HEPHAESTUS: A DIGITAL ATLAS FOR TRAINING AND STANDARDIZATION OF JOINT POINT-OF-CARE ULTRASOUND IN HEMOPHILIC ARTHROPATHY R. Gualtierotti1|2, N. D'Amico3, S. Mascetti3, M. Fassi1, A. Giachi1, C. Bettini3, F. Peyvandi1|2 | 1Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Milano, Italy; 2Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milano, Italy; 3Department of Computer Science, Università degli Studi di Milano, Milano, Italy
42PDF: 15 -
CO-36 | PLATELETS MATTER: THROMBIN GENERATION IN PLATELET‐RICH-PLASMA VS. PLATELET‐POOR‐PLASMA UNDER NON-REPLACEMENT THERAPIES IN HEMOPHILIA F. Bocchi1|2, R. Pastorino1|2, G. Murante1|2|3, S. Bergonzi1|2|3, M. Capetta1|2|3, F. Valeri2|3, C. Dainese2|3, A. Valpreda4, B. Bruno1|3, A. Borchiellini2|3 | 1Department of Molecular Biotechnology and Health Sciences, University of Turin, Italy; 2Regional Centre for Thrombotic and Hemorrhagic Diseases, AOU Città della salute e della Scienza di Torino, Italy; 3Division of Hematology, AOU Città della Salute e della Scienza, University of Turin, Italy; 4Central Lab Baldi and Riberi, AOU Città della salute e della Scienza di Torino, Italy
56PDF: 16 -
PO31 | Comparative analysis of anticoagulant therapy in patients over 90 years old: vitamin K antagonists versus direct oral anticoagulants G. Sottilotta1, P. Arrigo2, S. Cuzzocrea1, D. Megalizzi1, F. Luise3 | 1UOSD Microcitemie, Emostasi e Trombosi, Grande Ospedale Metropolitano di Reggio Calabria; 2Associazione Italiana Pazienti Anticoagulati, Sezione di Reggio Calabria; 3Laboratorio Analisi. Grande Ospedale Metropolitano di Reggio Calabria, Italy
605PDF: 18 -
Platelet distribution width is associated with cardiovascular mortality in an adult general population
3093PDF: 520Supplementary Material: 144 -
PO159 | HOW DOES DRUG ABSORPTION CHANGE IN THE PRESENCE OF NEOPLASTIC GASTROINTESTINAL DISEASE? M. Gagliardi, L. Capone, A. Ciampa | Centro Emostasi, AORN Moscati, Avellino, Italy
30PDF: 18 -
PO083 | WOMEN AND HEMOPHILIA: ASSESSMENT OF THE BLEEDING PHENOTYPE – ANALYSIS OF THE BRESCIA COHORT N. Portesi, S. Pontoglio, G. Carracchia, G. Albrici, E. Bertoni, G. Martini | ASST Spedali Civili di Brescia, Italy
39PDF: 13 -
CO-16 | VIRTUAL EVALUATIONS OF JOINT HEALTH USING WEARABLE SENSORS IN PERSONS WITH HEMOPHILIA: THE VESPA STUDY PROTOCOL S. Riva, R. Mahaffey | St. Mary's University London, UK
108PDF: 22 -
PO92 | Challenging management of portal vein thrombosis in a cirrhotic patient on hormone therapy after breast cancer L. Jr Valletta, C. De Luca, M. Aversano, C. Caputo, E. Cimino, P. Conca, A. Tufano, M.D. Di Minno | AOU Federico II Napoli, Italy
575PDF: 22 -
CO26 | Relationship between SMAD3 variants and non-aortic cardiovascular features L. Squillantini, E. Sticchi, P. Cantini, S. Suraci, A. Rogolino, F. Gensini, S. Nistri, G. Pepe, A.M. Gori, M. Berteotti, R. Marcucci, B. Giusti | Università degli Studi di Firenze, Dipartimento di Medicina Sperimentale e Clinica, Firenze, Italy
596PDF: 21 -
PO061 | LONG-TERM HEADACHE IMPROVEMENT WITH VITAMIN K ANTAGONISTS IN PRIMARY AND SECONDARY ANTIPHOSPHOLIPID SYNDROME: 2-YEAR OBSERVATIONAL COHORT A. Hoxha1|2, C. Belizna3, E. Esteve-Valverde4, A. Prundean5, A. Godon6, G. Gobbo1|2, A. Anunciación-Llunell7|8|9, R. Ferrer-Oliveras10, J.O. Latino11, S. Udry11, J. Alijotas-Reig7|8|9 | 1Department of Medicine, University of Padua, Padova, Italy; 2Internal Medicine Unit, Thrombosis and Bleeding Disorder Center, University Hospital of Padua, Padova, Italy; 3Vascular and Coagulation Department, University Hospital Angers, Angers, France; 4Systemic Autoimmune Diseases Unit, Department of Internal Medicine, Hospital Sant Camil, Consorci Sanitari del Garraf, Barcelona, Spain; 5University of Angers, Inserm, CNRS, MITOVASC, SFR ICAT, Angers, France; 6Centre Hospitalier Universitaire Angers, Institut National de la Santé et de la Recherche Médicale, Centre National de la Recherche Scientifique, Centre de Recherche en Cancérologie et Immunologie Intégrée Nantes Angers, Laboratoire d'Hématologie, Université d'Angers, Nantes Université, Angers, France; 7Department of Medicine, Universitat Autònoma de Barcelona, Spain; 8Systemic Autoimmune Disease Unit, Department of Internal Medicine, Vall d'Hebron University Hospital, Spain; 9Systemic Autoimmune Diseases Research Unit, Vall d'Hebron Institut de Recerca, Barcelona, Spain; 10Obstetrics Department, High-Risk Unit, Hospital Universitario Quirónsalud, Barcelona, Spain; 11Autoimmune, Thrombophilic Diseases and Pregnancy Division, Dr. Carlos G. Durand Hospital, Buenos Aires, Argentina
30PDF: 16 -
CO060 | LP(a) AND CARDIOVASCULAR RISK IN FAMILIAL HYPERCHOLESTEROLEMIA F. Basso1, G. Barbieri1, E. Sticchi1, A. Kura1, P. Cantini1, S. Suraci1, M. Berteotti1, E. Lotti1, F. Crudele1, G.M. Scaturro2, A. Rogolino1, A.M. Gori1, R. Marcucci1, B. Giusti1 | 1Atherothrombotic Diseases Center, Department of Experimental and Clinical Medicine, University of Florence, Careggi Hospital, Firenze, Italy; 2Meyer Children's Hospital IRCCS, Metabolic and Neuromuscular Unit, Firenze, Italy
45PDF: 22 -
CO-59 | CONCIZUMAB IN A YOUNG CHILD WITH SEVERE HEMOPHILIA B WITH INHIBITOR: EFFECTIVE BLEED CONTROL AND SAFE HOME MANAGEMENT T. Martini1, B. Borsellino1|2, B. Pollio1 | 1Hemophilia Centre, Immune-Haematology and Transfusion Medicine, University Hospital “Città della Salute e della Scienza”, Torino, Italy; 2Department of Biomedicine and Prevention, PhD in Immunology, Molecular Medicine and Applied Biotechnology, University of Rome Tor Vergata, Roma, Italy
55PDF: 17 -
BEST-07 | ULTRASOUND EVALUATION AND JOINT SCORING IN MILD HEMOPHILIA A: A SINGLE-CENTER CASE SERIES FOR THE IDENTIFICATION OF SUBCLINICAL ARTHROPATHY M. Leotta, A. Strangio, R.C. Santoro | Hemophilia Hemostasis and Thrombosis Unit, Azienda Ospedaliero Universitaria Renato Dulbecco, Catanzaro, Italy
147PDF: 19 -
PO096 | IDENTIFICATION OF A NEW VARIANT IN THE RASGRP2 GENE IN A CHILD WITH SUSPECTED GLANZMANN THROMBASTHENIA A. Ariano, A. Buonfiglio, M.F. D’Ambrosio, G. Cordisco, A. Leccese, A. Ranaldi, M. D’Apolito, R. Santacroce, M. Margaglione, G. D’Andrea | Lab. Genetica Medica, Policlinico Riuniti, Foggia, Italy
41PDF: 13 -
CO-27 | INNOVATIVE USE OF EPTACOG BETA TO TREAT ACUTE ELBOW HEMARTHROSIS IN A PEDIATRIC PATIENT WITH HEMOPHILIA B AND A HISTORY OF INHIBITORS, UNDERGOING SECONDARY PROPHYLAXIS WITH CONCIZUMAB L. Laterza1, P. Giordano2, G. Lassandro2 | 1University of Bari "Aldo Moro", Interdisciplinary Department of Medicine, Bari, Italy; 2Pediatric Haemophilia Center-AOUC Pol. Giovanni XXXIII, University of Bari “Aldo Moro”, Bari, Italy
62PDF: 18 -
PO071 | WHEN SJÖGREN’S DISEASE MIMICS TTP A. Castoldi, R. Rossio, F. Peyvandi | Medicina generale Osp. Maggiore Policlinico, Milano, Italy
32PDF: 17 -
CO095 | IMMATURE PLATELET FRACTION PREDICTS CLINICAL INSTABILITY IN CHRONIC IMMUNE THROMBOCYTOPENIA: PRELIMINARY RESULTS FROM THE PLATE-RET STUDY F. Boggio1|2, J.A. Giannotta1, M. Abbattista1, M. Clerici1, S. La Marca1, L. Padovan1|2, A. Truma1, A.C. Migliorini3, S. Torricelli3, A. Lecchi1|2, A. Artoni1 | 1Centro Emofilia e Trombosi A. Bianchi Bonomi, IRCCS Fondazione Ca' Granda Ospedale Maggiore Policlinico di Milano, Italy; 2Dip. di Fisiopatologia Medico-Chirurgica e dei Trapianti, Università degli Studi di Milano, Italy; 3Settore di Ematologia, Lab. Analisi, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico di Milano, Italy
44PDF: 14 -
CO-07 | ITALIAN RESOURCE USE IN MILD HEMOPHILIA A AND TYPE 1 VON WILLEBRAND DISEASE A. Gringeri1|2, G.C. Castaman3 | 1Fondazione Charta, Milano, Italy; 2Centro di Sanità Solidale, Lucca, Italy; 3Centre for Bleeding Disorders and Coagulation, Careggi University Hospital, Firenze, Italy
101PDF: 21 -
PO78 | Acquired hemophilia A as a paraneoplastic syndrome: two cases report on a rare coexistence M. Gagliardi, L. Capone, A. Ciampa | Centro Emostasi, AORN Moscati, Avellino, Italy
650PDF: 24 -
PO115 | AL AMYLOIDOSIS IN A PATIENT WITH SEVERE HEMOPHILIA A AND INHIBITORS WHO HAD A MONOZYGOTIC TWIN: SAME GENES, DIFFERENT OUTCOMES M. Biglietto, S. Sorella, S. Ligia, C. Andriola, R. Mormile, E. Baldacci, A. Chistolini, C. Santoro | Sapienza, University of Rome, Italy
32PDF: 14 -
CO-35 | TRANSITION FROM A PAEDIATRIC REFERRAL CENTER TO AN ADULT CENTER IN INHERITED BLEEDING DISORDERS: A REAL-WORLD COHORT STUDY I. Ricca1, A. Casson1, T. Martini2, B. Borsellino2, A. Barchieri1, G. Guido1, P. Ocello1, M. Tucciarone1, R. Albiani2, B. Pollio2, G. Delios1 | 1Centro Malattie Trombotiche ed Emorragiche - SC Servizio Trasfusionale ASL TO4, Ivrea, Italy; 2Centro Esperto Malattie Emorragiche Congenite in Età Pediatrica e della Donna in Gravidanza - SSD Medicina Trasfusionale Materno-Infantile e Traumatologica, Città della Salute e della Scienza di Torino, Italy
50PDF: 18 -
PO72 | CATHETER-RELATED THROMBOSIS VS. FIBROBLASTIC SLEEVE. INCIDENCE AND IMPACT IN ONCOLOGICAL AND HEMATOLOGICAL PATIENTS WITH PERIPHERALLY INSERTED CENTRAL CATHETER M. Nunziata1, S. Mangiacapra1, F.P. Damiano1, N. Iuliano1, V. Iorio1, R. Natale2, L. Santarpia2, M. Amitrano1 | 1Internal Medicine, A.O.R.N. San Giuseppe Moscati, Avellino, Italy; 2Internal Medicine, Department of Clinical Medicine and Surgery, Federico II University Hospital, Naples, Italy
530PDF: 122 -
PO158 | A RARE CASE OF ISCHEMIC STROKE: CAROTID WEBS C. Mazzei, I. Costanzo, D. Fumarulo, S. Bernardi, G. Trinchera, M. Littera, M. Mazzetti, C. Tamburini | Medicina Interna Interdisciplinare, A.O.U. Careggi, Firenze, Italy
61PDF: 15 -
PO082 | HEMOPHILIA AND LOW BONE MINERAL DENSITY: AN OBSERVATIONAL STUDY D. Fumarulo, R. Corrado, M. Canfora, M. Mazzetti, M. Littera, D. Prisco, C. Tamburini | Internal Medicine, Careggi Hospital, University of Florence, Firenze, Italy
53PDF: 16 -
PO002 | VENOUS THROMBOEMBOLISM IN PATIENTS WITH FACTOR VII DEFICIENCY: A CASE SERIES AND REVIEW OF THE LITERATURE BM. Roccon1, MI. Tassoni1, G. Quintavalle1, F. Riccardi1, A. Matichecchia1, GF. Rivolta1, M. Lombardi3, R. Rossi2, A. Benegiamo2, A. Tagliaferri1, A. Coppola1 | 1SSD Centro Hub Emofilia e Malattie Emorragiche Congenite, Azienda Ospedaliero-Universitaria di Parma, Italy; 2Lab. di Coagulazione, UOC Diagnostica Ematochimica, Azienda Ospedaliero-Universitaria di Parma, Italy; 3Centro Emostasi, UOC Medicina Interna ad indirizzo angiologico e coagulativo, Azienda Ospedaliero-Universitaria di Parma, Italy
42PDF: 16 -
CO-15 | HEMOPHILIA AND PHYSICAL ACTIVITY: A SURVEY ON THE CURRENT STATUS OF SPORTS ACCESSIBILITY IN THE ITALIAN POPULATION L. Laterza1, M. Attanasi1, C. Cassone2, P. Giordano3, G. Lassandro3 | 1University of Bari "Aldo Moro", Interdisciplinary of Medicine, Bari, Italy; 2Fedemo, Milano, Italy; 3Pediatric Haemophilia Center - AOUC Pol. Giovanni XXXIII, University of Bari "Aldo Moro", Italy
87PDF: 18 -
PO24 | WE ARE JUGGLING MANY POSSIBILITIES: HEALTHCARE PROFESSIONALS’ EXPERIENCES AND PERSPECTIVES ON INTERPRETATION OF PULMONARY EMBOLISM SIGNS AND SYMPTOMS IN PATIENTS WITH LUNG CANCER A.A. Højen1, M. Søgaard1, A.G. Ording1, M.R. Saugbjerg2, T.D. Christensen2|3, H.R. Jacobsen4, L. Jørgensen5, H. Enggaard5 | 1Danish Center for Health Services Research, Aalborg University Hospital; 2Department of Cardiothoracic Surgery, Aarhus University Hospital; 3Department of Clinical Medicine, Aarhus University Hospital; 4Department of Oncology, Aalborg University Hospital; 5Clinical Nursing Research Unit, Aalborg University Hospital, Denmark
502PDF: 99 -
CO049 | RANDOMIZED CONTROLLED TRIAL TO IDENTIFY THE OPTIMAL SCHEME OF HEPARIN FOR TREATMENT OF DEEP VEIN THROMBOSIS IN PREGNANCY E. Grandone1|3, E. Antonucci2, A. de Laurenzo1, L. Latino1, M. Mastroianno1, G. Tiscia1, M. Margaglione3, P. Prandoni2 | 1IRCCS Casa Sollievo della Sofferenza, S.Giovanni Rotondo, Italy; 2Fondazione Arianna, Italy; 3Università di Foggia, Italy
55PDF: 15 -
CO-55 | DEVELOPMENT OF ENGINEERED LONG-ACTING BYPASSING FX VIA ALBUMIN FUSION FOR HEMOPHILIA WITH INHIBITORS A. Martucci1, R. Tarantino1, K.H. Aaen2, M. Pinotti1, J.T. Andersen2, A. Branchini1 | 1Department of Life Sciences and Biotechnology, University of Ferrara, Ferrara, Italy; 2Institute of Clinical Medicine, Department of Pharmacology, University of Oslo, Norway
65PDF: 18 -
PO47 | Hemophilia A and antithrombin deficiency: a case of natural hemostatic rebalancing L. Torrieri, S. Ligia, E. Baldacci, R. Mormile, S. Sorella, R. Ciciani, M. Biglietto, N. Zhdanovskaya, A. Delli Paoli, A. Tirnetta, M. Lorenzon, C. Santoro | Hematology, Department of Translational and Precision Medicine, Policlinico Umberto I, Sapienza University of Roma, Italy
639PDF: 17 -
PO095 | HEPARIN-INDUCED THROMBOCYTOPENIA PRESENTING AS A CIRCUIT-TRIGGERED PULMONARY SYNDROME IN HEMODIALYSIS: A CASE REPORT S.P. Colapietra, M. Gino | Osp. Molinette, Torino, Italy
49PDF: 18 -
PO021 | PLATELETS MATTER: THROMBIN GENERATION IN PLATELET‐RICH PLASMA VERSUS PLATELET-POOR-PLASMA UNDER NON-REPLACEMENT THERAPIES IN HAEMOPHILIA F. Bocchi1|2, R. Pastorino1|2, G. Murante1|2|3, S. Bergonzi1|2|3, M. Capetta1|2|3, F. Valeri2|3, C. Dainese2|3, A. Valpreda4, B. Bruno1|3, A. Borchiellini2|3 | 1Department of Molecular Biotechnology and Health Sciences, University of Turin, Torino, Italy; 2Regional Centre for Thrombotic and Hemorrhagic Diseases; 3Division of Hematology; 4Central Lab Baldi and Riberi, AOU Città della salute e della Scienza di Torino, Torino, Italy
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CO-88 | TRANSIENT IDIOPHATIC ACQUIRED VON WILLEBRAND DISEASE: A RARE, CHALLENGING CONDITION WITH A POSSIBLE RAPID AND FAVORABLE EVOLUTION G. Murante1|2|3, S. Bergonzi1|2|3, M. Capetta1|2|3, F. Valeri1|2, C. Dainese1|2, A. Valpreda4, R. Pastorino1|3, F. Bocchi1|3, B. Bruno2|3, A. Borchiellini1|2 | 1Regional Centre for Hemorrhagic and Thrombotic Diseases, AOU Città della Salute e della Scienza of Turin, Italy; 2Division of Hematology, AOU Città della Salute e della Scienza, University of Turin, Italy; 3Dep. of Molecular Biotechnology and Health Sciences, University of Turin, Italy; 4Central Lab. Baldi and Riberi, AOU Città della Salute e della Scienza of Turin, Italy
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PO34 | INVESTIGATORS’ DECISIONS ON ANTICOAGULATION AFTER EXTENDED API-CAT TREATMENT FOR CANCER VENOUS THROMBOEMBOLISM I. Mahé1|4, F. Happe2, M. Monreal5|7, H. Robert-Ebadi8, P. Debourdeau9, J. R. Fabreguettes10, S. Accassat11, P. Mismetti4|11|12, P. Girard13, S. Laporte4|12|14, C. Chapelle14 | 1Paris Cité University; 2Assistance Publique - Hôpitaux de Paris, Louis Mourier Hospital, Department of Internal Medicine; 3Inserm UMR-S970, Paris Cardiovascular Research Center, Team « Endotheliopathy and Hemostasis Disorders », Paris, France; 4F-CRIN INNOVTE Network, France; 5Department of Internal Medicine, Institut de Recerca Germans Trias i Pujol, Hospital Universitari Germans Trias i Pujol, Badalona, Spain; 6Department of Medicine, Universitat Autonoma de Barcelona, Barcelona; 7Universidad Catolica San Antonio de Murcia, Murcia, Spain; 8Division of Angiology and Hemostasis, Faculty of Medicine, Geneva University Hospitals, Geneva, Switzerland; 9Arles Hospital, Oncology unit, Arles, France; 10Assistance Publique - Hôpitaux de Paris, AGEPS, France; 11Service de Médecine Vasculaire et Therapeutique, CHU de Saint-Etienne, Saint-Etienne, France; 12Université Jean Monnet, Mines Saint-Étienne, INSERM Unité 1059, Santé Ingénierie Biologie Saint-Étienne SAINBIOSE, Saint-Étienne, France; 13Département de Pneumologie, Institut Mutualiste Montsouris, Paris; 14Service de Pharmacologie Clinique, CHU de Saint-Etienne, Saint-Etienne, France
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PO070 | INFECTIVE ENDOCARDITIS AND ISCHEMIC CEREBRAL EVENTS IN A PATIENT WITH SYSTEMIC LUPUS ERYTHEMATOSUS AND TRIPLE ANTIPHOSPHOLIPID POSITIVITY: THE ROLE OF ANTICOAGULATION IN PRIMARY PREVENTION T. Marrazzo1, M.P. Ursi2, R. Andini1, R. Albisinni3 | 1UOC Med Interna e dei Trapianti; 2UOC Mecau; 3UOC CCH generale, Osp. Monaldi AORN dei Colli, Napoli, Italy
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CO-06 | ENHANCING SHARED DECISION-MAKING IN INHERITED BLEEDING DISORDERS: A SINGLE-CENTER QUALITY IMPROVEMENT INITIATIVE C. Manzi, L. Piscitelli, E. Zacchi, V. Caldi, L. Valdrè | Inherited Bleeding Disorders Unit, IRCCS AOU, Bologna, Italy
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PO76 | Thrombosis associated with midline in autoimmune patient: a case report on the use of apixaban in a real-world setting M.V. Cherchi, M. Anedda, S. Che, M. Vacca, M. Caboni, M. Mantega | Department of Internal Medicine, ASL Sulcis, Italy
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PO112 | REFRAMING THE ENIGMA: ACQUIRED HEMOPHILIA A AS A HARBINGER OF HHV-8–ASSOCIATED MULTICENTRIC CASTLEMAN DISEASE M. Palladino1, G. Gammaitoni1, C. Santoro2, M. Muscaritoli1 | 1Medicina Interna e Nutrizione Clinica-Dip. Medicina Traslazionale e di Precisione; 2Ematologia- Dip. Medicina Traslazionale e di Precisione, Umberto I Roma, Italy
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CO016 | PLATELET HYPER-REACTIVITY AND PROCOAGULANT PHENOTYPE IN ESSENTIAL THROMBOCYTHEMIA: INSIGHTS FROM ADVANCED PLATELET FUNCTION TESTING A. Pozzi, G. Rosati, C. Barale, M. Padrini, R.M. Medici, G. Ferrari, E. Mordohovich, M. Tamietti, M. Armenio, M. Geminiani, M. De Gobbi, I. Russo, A. Morotti | Dip. Scienze Cliniche e Biologiche, Torino, Italy
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PO29 | Quality of anticoagulation as a predictor of early left ventricular thrombosis resolution: a retrospective cohort study A. Pannunzio1, I.M. Palumbo1, M.P. Donadini2, D. Santagata2, W. Ageno2, F. Dragoni3, A. Chistolini3, C. Becattini4, K. Satula4, D. Menichelli1, D. Pastori1, P. Pignatelli5, E. Valeriani1 | 1Department of General Surgery and Surgical Specialty Paride Stefanini, Sapienza University of Roma; 2Department of Medicine and Surgery, University of Insubria, Varese; 3Hematology, Department of Translational and Precision Medicine, Sapienza University of Roma; 4Internal Vascular and Emergency Medicine - Stroke Unit, University of Perugia; 5Department of Clinical Internal, Anesthesiological and Cardiovascular Sciences, Sapienza University of Roma, Italy
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PO21 | PSYCHOLOGICAL IMPACT OF CANCER-ASSOCIATED THROMBOSIS: DUAL BURDEN AND IMPLICATIONS FOR QUALITY OF LIFE AND INTEGRATED PATIENT-CENTERED CARE G. Gerotziafas1|4, Y. Mitrou5, M. Marchetti6, P. Las Casa1, A. Tafur7, V. Bitsadze3, J. Khizroeva3, D. Taizhanova8, D. Antic9, C. Frére10, A. Makatsariya3, L. Garderet1|11, A. Escargueil1, C. Ay12, N. Lomatkin13, Z. Tazi-Mezalek14, M. Sassi15, M. Catalano4|16, J. Gligorov1|17, J. Caprini18, P. Van Dreden1|19, J. Fareed2, A. Falanga6 | 1Sorbonne University, INSERM UMR_S_938, CRSA, Research Department "Cancer, Vessels, Biology and Therapeutics" (CaVITE), Research Group "Cancer-Angiogenesis-Thrombosis and Haemostasis," Thrombosis Center, University Institute of Cancerology (UIC), Saint Antoine University Hospital Assistance Publique Hôpitaux de Paris (AP-HP)Paris France; 2Center of Translational Research and Education, Department of Pathology and Laboratory Medicine, Loyola University Stritch School of Medicine, Maywood, Chicago, USA; 3Thrombosis Center, Department of Obstetrics, Gynecology and Perinatal Medicine, The I. M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia; 4VAS-European Independent Foundation in Angiology/Vascular Medicine Milan Italy; 5Department of Phylosophy, National and Kapodistrian University of Athens, Greece; 6Department of Immunohematology and Transfusion Medicine, Hospital Papa Giovanni XXIII, Bergamo, Italy. School of Medicine and Surgery, University of Milan Bicocca, Milan, Italy; 7Vascular Medicine, Endeavor Health, Evanston, IL, USA; Pritzker School of Medicine, University of Chicago, Chicago, IL 60637, USA; 8Department of Internal Diseases, Karaganda Medical University Non-Commercial Joint Stock Company, Karaganda, Kazakhstan; 9Clinic for Hematology, University Clinical Center of Serbia, Faculty of Medicine University of Belgrade Belgrade Serbia; 10Department of Hematology, Pitié-Salpêtrière Hospital, Assistance Publique-Hôpitaux de Paris, Sorbonne Université, INSERM UMRS-1166 Institute of Cardiometabolism and Nutrition, Paris, France; 11Clinical Haematology Department, Sorbonne Université, Pitié-Salpêtrière Hospital, APHP, Paris; 12Department of Internal Medicine I, Clinical Division of Haematology and Haemostaseology, Medical University of Vienna, Vienna, Austria; 13Cardiology Division, Central Clinical Hospital of Presidential Administration, Moscow, Russia; 14Department of Internal Medicine, Hématologie Clinique, Centre Hospitalo-Universitaire Ibn Sina, Université Mohammed V de Rabat, Rabat, Morocco; 15Hematology Laboratory of Maternity and Neonatal Center of Monastir, Faculty of Pharmacy of Monastir, Monastir, Tunisia; 16Inter-University Research Center on Vascular Diseases, University of Milan-L Sacco Hospital, Milan, Italy; 17Medical Oncology Department, Tenon Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Sorbonne University, Paris, France; 18Vascular Surgery, Pritzker School of Medicine at the University of Chicago, Chicago, USA; 19Clinical Research, Diagnostica Stago, Gennevilliers, France
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PO91 | Disseminated intravascular coagulation with deep vein thrombosis in a frail patient: an extreme manifestation triggered by sepsis during SGLT2i therapy M. Vacca1, M.V. Cherchi1, S. Che1, G.A.M.L. Costanzo2, D. Firinu2, M. Mantega1, S. Del Giacco2 | 1Ospedale Sirai, ASL Sulcis, 2Università degli Studi di Cagliari, Italy
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CO10 | Multidimensional risk assessment of venous thromboembolism: an observational study comparing the Padua prediction score, Barthel index, and quality of life in hospitalized patients A. Mameli, S. Cornacchini, P. Schirru, F. Marongiu, D. Barcellona | Hemostasis and Thrombosis Unit, University of Cagliari, Italy
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PO125 | ROMIPLOSTIM FOR CHEMOTHERAPY-INDUCED THROMBOCYTOPENIA IN ADVANCED SOLID TUMORS: A SINGLE-CENTER EXPERIENCE G. Giustini1, A. Baffioni1, C. Giubbilei1, A.M. Vannucchi2, V. Carrai3 | 1SOD Ematologia, Università degli studi di Firenze, Italy; 2Center for Research and Innovation of Myeloproliferative Neoplasms, SOD Ematologia, AOU Careggi, Università degli studi di Firenze, Italy; 3SOD Ematologia, Dipartimento di Oncologia, AOU Careggi, Firenze, Italy
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PO056 | SYNERGISTIC EFFECT OF RECOMBINANT FACTOR INFUSION ON THROMBIN GENERATION IN HEMOPHILIA PATIENTS UNDER EMICIZUMAB OR CONCIZUMAB PROPHYLAXIS F. Bocchi1|2, R. Pastorino1|2, M. Capetta1|2|3, S. Bergonzi1|2|3, G. Murante1|2|3, F. Valeri2|3, C. Dainese2|3, A. Valpreda4, B. Bruno1|3, A. Borchiellini2|3 | 1Department of Molecular Biotechnology and Health Sciences, University of Turin, Italy; 2Regional Center for Thrombotic and Hemorrhagic Diseases; 3Division of Hematology; 4Central Lab Baldi and Riberi, AOU Città della Salute e della Scienza di Torino, Italy
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CO041 | GLOBAL COAGULATION ASSESSMENT FOR THE RISK OF HEAVY MENSTRUAL BLEEDING IN WOMEN ON ORAL ANTICOAGULANT THERAPY – THE COHMBO STUDY M. Abbattista, E. Scalambrino, M. Clerici, A. Truma, A. Artoni, P. Bucciarelli | Fondazione IRCCS Ca' Granda Policlinico, Italy
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CO-50 | LEFT ATRIAL APPENDAGE OCCLUSION IN PATIENTS WITH ATRIAL FIBRILLATION AND BLEEDING DISORDERS: A SINGLE-CENTER EXPERIENCE B.M. Roccon1, M.I. Tassoni1, G. Quintavalle1, G. Benatti2, F. Gurgoglione2, R. Rossi3, C. Cattabiani3, L. Vignali2, A. Tagliaferri1, A. Coppola1 | 1SSD Centro Hub Emofilia e Malattie Emorragiche Congenite, Azienda Ospedaliero-Universitaria di Parma, Italy; 2SSD Cardiologia Interventistica, Azienda Ospedaliero-Universitaria di Parma, Italy; 3Laboratorio di Coagulazione, UOC Patologia Clinica, Azienda Ospedaliero-Universitaria di Parma, Italy
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PO094 | ARTIFICIAL INTELLIGENCE IN PULMONARY EMBOLISM PHENOTYPING: A SCOPING REVIEW D. Santagata1, A. Abenante1, S. Cosci2, D. Steiner3, S. Nopp3, A. Squizzato1, M.P. Donadini1, F. Dentali1, C. Ay3, W. Ageno4 | 1Department of Medicine and Surgery, University of Insubria, Varese and Como, Italy; 2Department of Internal Medicine, Ente Ospedaliero Cantonale (EOC), Bellinzona, Switzerland; 3Clinical Division of Haematology and Haemostaseology, Department of Medicine I, Comprehensive Cancer Center Vienna, Medical University of Vienna, Vienna, Austria; 4Department of Medicine, University of Padova, Padova, Italy
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CO-87 | SPONTANEOUS HEMATOMA IN A PATIENT WITH POLYCYTHEMIA VERA: A CASE OF ACQUIRED VON WILLEBRAND DISEASE? A. Strangio, A. Ierardi, M. Leotta, R.C. Santoro | Hemophilia center, AOU Renato Dulbecco, Catanzaro, Italy
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CO-22 | CLINICAL FEATURES IN PATIENTS WITH NON-SEVERE HEMOPHILIA A: THE DISCOVERY SCORE PROPOSAL FOR PROPHYLAXIS PRESCRIPTION M.N.D. Di Minno1, E. Baldacci2, C. Biasoli3, A. Borchiellini4, F. Daniele5, P. Di Gregorio6, C. Gorio7, G. Malcangi8, E. Marchesini9, I. Ricca10, R. Santoro11, S. Siragusa12, M.R. Villa13, E. Zanon14, A. Tagliaferri15, A. Coppola15 | 1Hub Centre for Thrombotic and Hemorrhagic Disorders, Federico II University Hospital, Napoli, Italy; 2Haematology, University Hospital Policlinico Umberto I, Roma, Italy; 3Interdepartmental Simple Structure for the Management of Hemorrhagic and Thromboembolic Diseases, M. Bufalini Hospital, Cesena, Italy; 4Regional Centre for Hemorrhagic and Thrombotic Diseases, AOU Città della Salute e della Scienza, Torino, Italy; 5Haemostasis and Thrombosis Service, Ospedale Civile dell'Annunziata, Cosenza, Italy; 6Transfusion Medicine Department, "SS. Annunziata" Hospital, Chieti, Italy; 7Pediatric Onco-Hematology Unit, Children's Hospital, ASST-Spedali Civili, Brescia, Italy; 8Haemophilia and Thrombosis Center, University Hospital Policlinico-Giovanni XXIII, Bari, Italy; 9Hemophilia Centre, SC Vascular and Emergency Department, University of Perugia, Italy; 10Centro Emofilia, Città della Salute e della Scienza, Torino, Italy; 11Hemostasis and Thrombosis Unit, Azienda Ospedaliero Universitaria Dulbecco, Catanzaro, Italy; 12Centro di Riferimento Regionale per le Emocoagulopatie Congenite, Palermo, Italy; 13Hematology Unit, Ospedale Santa Maria di Loreto, Napoli, Italy; 14Hemophilia and Thrombosis Center, University Hospital of Padua, Italy; 15Hemophilia and Thrombosis Center, Azienda Ospedaliera di Parma, Italy
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PO31 | MIGRATORY SUPERFICIAL THROMBOPHLEBITIS REFRACTORY TO APIXABAN IN A PATIENT WITH LUNG ADENOCARCINOMA I. Goldberg1|2, P. Raanani1|2|3, G. Spectre1|2 | 1Institute of Hematology, Beilinson Hospital, Rabin Medical Center, Petah Tikva, Israel; 2Faculty of Medical & Health Sciences, Tel Aviv University, Tel Aviv, Israel; 3Felsenstein Medical Research Center, Rabin Medical Center, Petah Tikva, Israel
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CO32 | Major surgery in patients with severe hemophilia A without inhibitors receiving prophylaxis with fitusiran E. Zanon, C. Simion, A. Napolitano, L. Spiezia, P. Simioni | Haemophilia Center, First Chair of Internal Medicine, Department of Medicine, University-Hospital of Padua Medical School, Padua, Italy
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PO140 | HISTORY OF FALLS IN PATIENTS WITH ATRIAL FIBRILLATION: A SYSTEMATIC REVIEW AND META-ANALYSIS A.P. Speziale1, G. Buoninfante1, A. Ronca2|4, B. Corica3, V. Trapani1, M. Moretti1, G. Annecchini1, R. Cangemi1, V. Raparelli1, M. Proietti2|4, S. Basili1, G.F. Romiti5 | 1Department of Translational and Precision Medicine, Sapienza University of Roma, Roma, Italy; 2Department of Clinical Sciences and Community Health, University of Milano, Milano, Italy; 3University of Modena and Reggio Emilia, Modena, Italy; 4Division of Subacute Care, IRCCS Istituti Clinici Scientifici Maugeri, Milano, Italy; 5Department of Wellbeing, Health and Environmental Sustainability, Sapienza University of Roma, Rieti, Italy
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CO090 | DIRECT ORAL ANTICOAGULANTS IN THE SECONDARY PREVENTION OF VENOUS THROMBOEMBOLISM IN PATIENTS WITH SEVERE INHERITED THROMBOPHILIA: A REAL-WORLD MULTICENTER STUDY A. Tufano1, I.L. Calcaterra1, E. Valeriani2, E. Cimino1, P. Madonna3, A. Guida4, P. Rufolo1, F. Strano1, R. Russo1, A. Casoria5, M. Amitrano5, P. Pignatelli2, M. Di Minno1 | 1Department of Clinical Medicine and Surgery, University of Naples, Federico II, Napoli, Italy; 2Department of Internal Medicine, Endocrine and Metabolic Sciences, and Infectious Diseases. Umberto I Hospital of Roma, Italy; 3Thrombotic Unit, Ospedale del Mare, Napoli, Italy; 4Center for Congenital Bleeding Disorders and Thrombosis, AOU S.Giovanni di Dio and Ruggi d'Aragona, Salerno, Italy; 5UOC Medicina Interna, AORN Moscati, Avellino, Italy
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CO-04 | INTEGRATING EXPERTISE: IMPLEMENTATION OF A MULTIDISCIPLINARY PATHWAY FOR GENETIC TESTING AND COUNSELLING IN INHERITED BLEEDING DISORDERS E. Zacchi1|2, L. Piscitelli1, C. Manzi1, L. Godino2, F. Riccardi3, A. Vaisfeld2|4, L. Valdrè1 | 1Inherited Bleeding Disorders Unit, IRCCS AOUBO, Bologna, Italy; 2Medical Genetics Unit, IRCCS AOUBO, Bologna, Italy; 3Regional Hub Centre for Hemophilia and Inherited Bleeding Disorders, University Hospital of Parma, Italy; 4Department of Medical and Surgical Sciences, University of Bologna, Italy
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PO110 | CLINICAL OUTCOMES AND SURVIVAL OF UNUSUAL SITE VENOUS THROMBOSIS IN PATIENTS WITH AND WITHOUT MYELOPROLIFERATIVE NEOPLASMS: A RETROSPECTIVE SINGLE-CENTER STUDY I. Bertozzi, M.T. Sartori, G. Libralon, M. Zerbinati, A. Galbiati, P. Simioni | Department of Medicine, University of Padova, Italy
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CO015 | EVOLUTION OF ANTICOAGULANT THERAPY FOR CANCER-ASSOCIATED THROMBOSIS: THE START2 REGISTRY ONCO-VTE LONGITUDINAL STUDY M. Marchetti1|2, T. Zollner1|2, O.C. Cretu1|2, A. Chistolini3, R. Pancani4, L. Puccetti5, P. Sivera6, W. Ageno7, G. Elmi8, V. Fregoni9, V. Tonelli10, E. Antonucci11, D. Poli11|12, A. Falanga1|2, L. Barcella1|2 | 1Hemostasis & Thrombosis Center, Department of Transfusion Medicine, Papa Giovanni XXIII Hospital, Bergamo, Italy; 2ERN EuroBloodNet; 3Hematology Unit, Department of Translational and Precision Medicine, Sapienza University of Roma, Roma, Italy; 4Pulmonary Unit, Hospital of Siena, University of Siena, Siena, Italy; 5Hemostasis and Thrombosis Unit, Hospital of Siena, University of Siena, Siena, Italy; 6Haematology Unit, Ordine Mauriziano Hospital, Torino, Italy; 7Department of Medicine, University of Padua, Padova, Italy; 8Department of Medicine, Maggiore Hospital, Bologna, Italy; 9Department of Medicine, Sondalo Hospital, Sondalo, Italy; 10Angiology Unit, Sant'Eugenio Hospital, Roma, Italy; 11Arianna Anticoagulazione Foundation, Bologna, Italy; 12Department of Critical Care Medicine, Thrombosis Centre, Azienda Ospedaliera Universitaria Careggi, Firenze, Italy
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PO58 | TACKLING THE AWARENESS GAP IN CANCER-ASSOCIATED THROMBOSIS: IMPACT OF A BRIEF EDUCATIONAL INTERVENTION IN PATIENTS WITH GYNECOLOGICAL CANCERS P. Santini, F. Mancinetti, G. Fracassa, E. Fondi, E. Ianuà, A. D'Errico, M. Bigossi, C. Marchetti, V. Salutari, G. Scambia, C. Nero, R. Pola | Agostino Gemelli University Hospital Foundation IRCCS, Rome, Italy
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PO080 | BEYOND STANDARD COAGULOPATHY: SEVERE FACTOR XIII DEFICIENCY AS THE HARBINGING SIGN OF ACUTE PROMYELOCYTIC LEUKEMIA L. Banov, G. Gazzelli, C. Vernarecci, F. Marotta, F. Giacopelli, B. Tappino, B. Antonioli, A.C. Molinari | IRCCS Istituto Giannina Gaslini Genova, Italy
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CO-75 | ASSAY DISCREPANCY IN HEMOPHILIA A CARRIERS: CLINICAL AND GENETIC INSIGHTS M. Leotta, A. Strangio, A. Ierardi, R.C. Santoro | Hemophilia Treatment Center AOU Dulbecco, Catanzaro, Italy
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CO09 | Long term effectiveness and safety of direct oral anticoagulants in patients with factor V Leiden and/or prothrombin gene mutation and venous thromboembolism: a single centre, retrospective cohort study I.M. Palumbo1, E. Valeriani1,2, A. Pannunzio1, S. Marucci3, D. Menichelli1, D. Pastori3,4, P. Pignatelli3 | 1Department of General Surgery and Surgical Specialty, Sapienza University of Roma; 2Department of Infectious Disease, Azienda Ospedaliero-Universitaria Policlinico Umberto I, Roma; 3Department of Clinical Internal, Anaesthesiologic and Cardiovascular Sciences, Sapienza University of Roma; 4IRCCS Neuromed, Pozzilli, Italy
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PO124 | BLEEDING COMPLICATIONS DURING ANTICOAGULATION WITH DOACS FOR NVAF AND THEIR MOST COMMON RISK FACTORS A. delle Femine, P. Di Micco, P. Sommese, M. Di Napoli, A. Di Salvatore, M. Galdiero, A. Lobasso, R. Serpico, V. Brunelli, A. Di Fusco, C. di Gennaro | U.O.C. Medicina Interna, Osp. Santa Maria delle Grazie, Pozzuoli, Italy
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PO050 | HEMOSTATIC AND FIBRINOLYTIC PROFILES IN PATIENTS UNDERGOING TAVI: PRELIMINARY RESULTS ON HOMOCYSTEINE, D-DIMER, AND CLOT LYSIS TIME V. Scheggi1, A. Bertelli2, F. Cesari3, A. Rogolino3, G. Ciarrocca Taranta2, M. Di Gioia3, G. Barbieri2, A.M. Gori2|3, R. Marcucci2|3 | 1Dep of Cardiothoracovascular Medicine, Careggi University Hospital, Firenze, Italy; 2Dep of Experimental and Clinical Medicine, University of Florence, Italy; 3Atherothrombotic Diseases, Careggi University Hospital, Firenze, Italy
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CO-45 | BRIDGING THE CLINICAL CHASM: GENETIC ANALYSIS AS A CONFIRMATORY TOOL IN MISMATCHED GLANZMANN THROMBASTHENIA R. Pastorino1|3, F. Bocchi1|3, A. Valpreda4, G. Murante1|2|3, S. Bergonzi1|2|3, M. Capetta1|2|3, F. Valeri1|2, C. Dainese1|2, M. Gilestro5, D. Peruccio6, E. De Candia7, P. Concolino8, B. Bruno2|3, A. Borchiellini1|2 | 1Regional Centre for Hemorrhagic and Thrombotic Diseases, AOU Città della Salute e della Scienza, Italy; 2Division of Hematology, AOU Città della Salute e della Scienza and University of Turin, Italy; 3Department of Molecular Biotechnology and Health Sciences, University of Turin, Italy; 4Central Laboratory Baldi and Riberi, AOU Città della Salute e della Scienza di Torino, Italy; 5AOU Citta' della Salute e della Scienza, PO Molinette, Anatomy and Pathological Histology 1 U, Department of Laboratory Medicine - Flow Cytometry Laboratory, Torino, Italy; 6AOU Citta' della Salute e della Scienza di Torino, Maternal-Infant and Trauma Transfusion Medicine, Regina Margherita Hospital, Department of Laboratory Medicine, Torino, Italy; 7Haemostasis and Thrombosis Unit, Fondazione Policlinico Universitario A.Gemelli, IRCCS, Department of Translational Medicine, Università Cattolica del Sacro Cuore, Roma, Italy; 8Fondazione Policlinico Universitario A. Gemelli, IRCCS, Department of Laboratory and Hematological Sciences, Unit of Clinical Chemistry, Biochemistry and Molecular Biology, UOSD of Molecular and Genomic Diagnostics, Roma, Italy
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PO43 | Extended treatment with reduced dose of direct oral anticoagulants in patients with venous thromboembolism: a retrospective study A. Pannunzio1, E. Valeriani1, I.M. Palumbo1, D. Menichelli1, T. Brogi2, S. Marucci2, D. Pastori2, P. Pignatelli2 | 1Department of General Surgery and Surgical Specialty, Sapienza University of Roma; 2Department of Clinical Internal, Anesthesiological and Cardiovascular Sciences, Sapienza University of Roma, Italy
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Diagnosis and management of abnormal uterine bleeding in adolescence An expert Consensus Statement of SIGO (Italian Society of Gynecology and Obstetrics) and SISET (Italian Society for the Study of Hemostasis and Thrombosis)
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PO013 | COMPLEX COAGULATION PROFILE IN ALG8-CDG: EXPANDING CLINICAL RECOGNITION OF A RARE DISORDER R. Santacroce1, M. Schiavulli2, G. D'Andrea1, G. Luca Tiscia3, F. Cappucci3, M.L. Tramontano2, E. Grandone3|4, M. Margaglione1 | 1Genetica Medica - Dip.to di Medicina Clinica e Sperimentale, Università di Foggia, Italy; 2Haemophilia and Congenital Bleeding Disorders, Treatment Center Santobono-Pausilipon Children Hospital, AORN, Napoli, Italy; 3Unità di Emostasi e Trombosi, IRCCS "Casa Sollievo della Sofferenza", San Giovanni Rotondo (FG), Italy; 4Ostericia e Ginecologia, Dip.to di Scienze Mediche e Chirurgiche, Università di Foggia, Italy
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CO-83 | ACQUIRED FACTOR V DEFICIENCY IN A HIGH-THROMBOTIC-RISK PATIENT: DIAGNOSTIC DILEMMA AND SUCCESSFUL MANAGEMENT G. Gazzelli1, L. Banov1, Y. Azzanelli1, C. Vernarecci1, F. Marotta1, F. Giacopelli1, E. Cenni2, V. Agostini2, A.C. Molinari1 | 1IRCCS Istituto Giannina Gaslini, Italy; 2IRCSS AOM S. Martino, Genova, Italy
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PO067 | LONG‑TERM SAFETY AND EFFECTIVENESS OF VITAMIN K ANTAGONISTS IN PATIENTS WITH ANTIPHOSPHOLIPID ANTIBODIES: A RETROSPECTIVE COHORT ANALYSIS G. Sottilotta1, G. Praticò1, D. Megalizzi1, F. Luise2 | 1UOSD Centro per le Microcitemie - Servizio Emostasi e Trombosi; 2Laboratorio Analisi, Grande Ospedale Metropolitano di Reggio Calabria, Italy
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CO089 | LONG-TERM RISK OF VENOUS THROMBOEMBOLISM IN AUTOIMMUNE HEMOLYTIC ANEMIA: A SYSTEMATIC REVIEW AND META-ANALYSIS L. Panepinto, M. Merlo, F. Zoccatelli, G. Costa, N. Martinelli, S. Friso, L. Marzano | Department of Medicine, Unit of Internal Medicine B, University of Verona, Verona, Italy
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