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Bleeding, Thrombosis and Vascular Biology

Editor-in-Chief: Giovanni de Gaetano, Italy | eISSN: 2785-5309

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  • The key to fibrinolysis and thrombolysis

    Roger Lijnen, Désiré Collen
    09-09-2025
    https://doi.org/10.4081/btvb.2025.368
    222
    PDF: 52
    HTML: 34
  • Attitude to clinical research among health professionals affiliated with the Italian Federation of Centers for the Diagnosis of Thrombotic Disorders and the Surveillance of the Antithrombotic Therapies (FCSA)

    Daniela Poli, Riccardo Tartaglia, Doris Barcellona , Paolo Bucciarelli , Antonio Ciampa, Elvira Grandone, Giuseppe Malcangi, Giuseppe Rescigno, Vincenzo Toschi, Sophie Testa, Alessandro Squizzato
    21-03-2023
    https://doi.org/10.4081/btvb.2023.59
    634
    PDF: 244
  • Patient and public involvement in cancer-associated thrombosis research: necessary or glorified tokenism?

    Simon Noble
    16-05-2024
    https://doi.org/10.4081/btvb.2024.125
    1274
    PDF: 305
  • Restrained glycoprotein VI-induced platelet signaling by tyrosine protein phosphatases independent of phospholipase Cγ2

    Jingnan Huang, Delia I. Fernández, Jinmi Zou, Xueqing Wang, Johan W.M. Heemskerk, Ángel García
    11-10-2023
    https://doi.org/10.4081/btvb.2023.93
    484
    PDF: 194
  • Hemostasis and the kidney: an unforeseen initial opportunity to create a small research group that grew into an institute

    Carlamaria Zoja, Ariela Benigni, Giuseppe Remuzzi
    30-06-2025
    https://doi.org/10.4081/btvb.2025.190
    279
    PDF: 49
    Supplementary: 12
  • A commitment to global collaboration, welcoming international participation and advancing science for the benefit of patients

    Pantep Angchaisuksiri, Wolfram Ruf, Jeffrey Weitz, Sam Schulman, Guy A. Young
    01-07-2025
    https://doi.org/10.4081/btvb.2025.188
    1022
    PDF: 147
    HTML: 0
  • Thrombosis and hemostasis at the University of Padua: a reappraisal on the occasion of its 800th year of history

    Paolo Simioni, Vittorio Pengo, Paolo Prandoni
    07-11-2022
    https://doi.org/10.4081/btvb.2022.52
    2122
    PDF: 249
  • https://BioRender.com/zrlk3rh

    The subtle red line between combating and resolving inflammation in the cardiovascular disease, a “silent sniper”

    Ciarán Kennedy, Luke J. Conroy, Braden Millar, Monica de Gaetano
    30-06-2025
    https://doi.org/10.4081/btvb.2025.187
    845
    PDF: 156
  • Circulating albumin-to-fibrinogen ratio may be a risk indicator for venous thromboembolism: findings from a population-based prospective cohort study

    Setor K. Kunutsor, Sudhir Kurl, Ari Voutilainen, Jari Laukkanen
    14-07-2022
    https://doi.org/10.4081/btvb.2022.36
    1098
    PDF: 245
  • Plasma fibrinogen levels and all-cause and cause-specific mortality in an Italian adult population: results from the Moli-sani study

    Roberta Parisi, Simona Costanzo, Romy de Laat-Kremers, Augusto Di Castelnuovo, Amalia De Curtis, Teresa Panzera, Mariarosaria Persichillo, Chiara Cerletti, Giovanni de Gaetano, Maria Benedetta Donati, Licia Iacoviello, Bas de Laat , for the Moli-sani Study Investigators
    27-01-2023
    https://doi.org/10.4081/btvb.2023.46
    1722
    PDF: 438
    APPENDIX: 113
  • Coagulome and tumor microenvironment: impact of oncogenes, cellular heterogeneity and extracellular vesicles

    Nadim Tawil, Lata Adnani, Janusz Rak
    16-05-2024
    https://doi.org/10.4081/btvb.2024.109
    516
    PDF: 277
  • On the impact of generative artificial intelligence on peer review

    Giovanni de Gaetano, Chiara Cerletti, Augusto Di Castelnuovo
    03-03-2025
    https://doi.org/10.4081/btvb.2025.176
    764
    PDF: 254
  • Crosstalk between hemostasis inhibitors and cholesterol biomarkers in multiple sclerosis

    Robert Parambi, Nicole Ziliotto, Francesco Bernardi , Marcello Baroni , Richard W Browne , Dejan Jakimovski, Bianca Weinstock-Guttman, Robert Zivadinov, Murali Ramanathan
    17-10-2022
    https://doi.org/10.4081/btvb.2022.41
    2325
    PDF: 276
    Supplementary Files: 68
  • Unveiling the “common soil” of cardiovascular disease and cancer

    Licia Iacoviello, Maria Benedetta Donati
    24-02-2025
    https://doi.org/10.4081/btvb.2025.167
    813
    PDF: 243
  • The evolution of hemostasis genetics: from monogenic disorders to complex traits. A historical perspective

    Augusto Di Castelnuovo
    01-07-2025
    https://doi.org/10.4081/btvb.2025.184
    835
    PDF: 141
  • The Lefoulon Delalande Foundation honors the lymphatic vascular system

    Anne Eichmann
    26-10-2023
    https://doi.org/10.4081/btvb.2023.99
    2408
    PDF: 207
  • Anticoagulation in obese patients: challenges and strategies

    Alice Lipari, Esmeralda Capristo, Antonietta Ferretti, Erica De Candia
    18-09-2025
    https://doi.org/10.4081/btvb.2025.174
    172
    PDF: 32
    HTML: 22
  • Comparison among three different bleeding scores and the thrombin generation assay to assess the different hemorrhagic phenotypes in patients with FVII deficiency

    Samantha Pasca, Cristina Santoro, Chiara Ambaglio, Marisanta Napolitano, Marta Milan, Letizia Natali, Silvia Nannizzi, Filippo Mori, Paolo Simioni, Ezio Zanon
    23-05-2022
    https://doi.org/10.4081/btvb.2022.12
    5084
    PDF: 328
  • Descriptive analysis of patients positive for anti-phospholipid antibodies included in two Italian registries

    Vittorio Pengo, Luca Sarti, Emilia Antonucci, Stefania Di Agostino, Elisa Bison, Gentian Denas, Daniela Poli, Pier Luigi Meroni, Roberto Gerli, Antonella Radice, Gualtiero Palareti, on behalf of FIRMA group and START collaborators
    12-10-2023
    https://doi.org/10.4081/btvb.2023.92
    858
    PDF: 256
  • Da la scheggia rotta usciva insieme parole e sangue: an unusual case of bleeding and the metaphor of a clinical trial

    Giovanni de Gaetano
    29-10-2024
    https://doi.org/10.4081/btvb.2024.156
    1481
    PDF: 288
    Appendix: 199
  • Milvexian and other drugs targeting Factor XI: a new era of anticoagulation?

    Marco P. Donadini, Walter Ageno
    15-04-2022
    https://doi.org/10.4081/btvb.2022.22
    2080
    PDF: 560
  • Trends and updates on the epidemiology of cancer-associated thrombosis: a systematic review

    Ang Li, Emily Zhou
    16-05-2024
    https://doi.org/10.4081/btvb.2024.108
    920
    PDF: 446
  • The use of creatine and the development of deep vein thrombosis. A scoping review

    Kartik Akkihal, Thomas Varkey, James Kelbert
    18-11-2024
    https://doi.org/10.4081/btvb.2024.142
    4298
    PDF: 332
    Supplementary: 118
  • Rationale and design of a study on D-dimer use to stratify patients after a first unprovoked venous thromboembolism for their risk of recurrence: extended low-dose Apixaban given only to patients with positive D-dimer results The Apidulcis study

    Gualtiero Palareti, Paolo Prandoni, Cristina Legnani, Emilia Antonucci, Serena Zorzi, Alberto Tosetto, Lorenza Bertù, Sophie Testa, Vittorio Pengo, Walter Ageno, Ida Martinelli, Benilde Cosmi, Eugenio Bucherini, Daniela Poli
    22-03-2022
    https://doi.org/10.4081/btvb.2022.10
    1176
    PDF: 380
    APPENDIX: 77
  • Blood platelets, prostaglandins and aspirin: a historical and personal rereading

    Giovanni de Gaetano, Chiara Cerletti
    13-03-2024
    https://doi.org/10.4081/btvb.2024.121
    1368
    PDF: 241
  • SISET50: trajectories of hemostasis and thrombosis in Italy 1970-2020

    Giovanni de Gaetano, Maria Benedetta Donati, Americo Bonanni
    17-01-2025
    https://doi.org/10.4081/btvb.2025.170
    1056
    PDF: 224
  • Platelet distribution width is associated with cardiovascular mortality in an adult general population

    Benedetta Izzi, Simona Costanzo, Alessandro Gialluisi, Amalia De Curtis, Sara Magnacca, Teresa Panzera, Augusto Di Castelnuovo, Maria Benedetta Donati, Chiara Cerletti, Marc F. Hoylaerts, Giovanni de Gaetano, Licia Iacoviello, *on behalf of the Moli-sani Study Investigators
    27-09-2023
    https://doi.org/10.4081/btvb.2023.83
    1984
    PDF: 299
    Supplementary Material: 54
  • https://pixabay.com/users/geralt-9301/?utm_source=link-attribution&utm_medium=referral&utm_campaign=image&utm_content=1571860

    Artificial intelligence and machine learning in hemostasis and thrombosis

    Paolo Gresele
    30-12-2023
    https://doi.org/10.4081/btvb.2023.105
    2608
    PDF: 551
  • Antithrombotic therapy in idiopathic infertility

    Fabio Tumminello, Silvia Cardi, Corrado Lodigiani, Maria Elisa Mancuso
    03-10-2024
    https://doi.org/10.4081/btvb.2024.126
    2079
    PDF: 529
  • The 2024 Nobel prize in Medicine: impact on hemostasis and thrombosis research

    Loredana Bury, Marco Malvestiti, Paolo Gresele
    19-11-2024
    https://doi.org/10.4081/btvb.2024.159
    1031
    PDF: 234
  • The night of randomized clinical trials where all patients are black: a need to estimate variability in treatment effects

    Giovanni de Gaetano, Chiara Cerletti, Licia Iacoviello, Maria Benedetta Donati
    22-03-2022
    https://doi.org/10.4081/btvb.2022.24
    1856
    PDF: 271
  • 2024 EACTS guidelines on perioperative medication in adult cardiac surgery: embracing precision medicine driven by strong evidence-based methodology

    Bianca Rocca, Emma Hansson, Milan Milojevic, Anders Jeppsson
    01-07-2025
    https://doi.org/10.4081/btvb.2025.178
    1186
    PDF: 191
  • Venous thromboembolism and mortality in patients with hematological malignancies

    Kristen M. Sanfilippo, Tzu-Fei Wang
    16-05-2024
    https://doi.org/10.4081/btvb.2024.119
    816
    PDF: 377
  • It’s definitely time to consider diet in its ultra-processing form as a major risk factor for thrombotic vascular disorders

    Marialaura Bonaccio, Licia Iacoviello, Maria Benedetta Donati
    03-08-2023
    https://doi.org/10.4081/btvb.2023.91
    1180
    PDF: 244
  • Factor XI inhibitors: a new option for the prevention and treatment of cancer-associated thrombosis

    Marcello Di Nisio, Matteo Candeloro, Nicola Potere, Ettore Porreca, Jeffrey I. Weitz
    16-05-2024
    https://doi.org/10.4081/btvb.2024.118
    967
    PDF: 444
  • The role of dyslipidemia and gender-related risk factors in the management of patients with abdominal aortic aneurysms: a survey from the Italian Society of Angiology and Vascular Medicine and a call to action

    Martina Berteotti, Walter Ageno, Rossella Marcucci, Andrea Stella, Paolo Zamboni, Romeo Martini
    30-06-2025
    https://doi.org/10.4081/btvb.2025.164
    779
    PDF: 118
  • Factor XI inhibitors in adjunct to antiplatelet therapy: the ultimate dual-pathway inhibition?

    Mattia Galli, C. Michael Gibson, Dominick J. Angiolillo
    03-08-2023
    https://doi.org/10.4081/btvb.2023.90
    1463
    PDF: 482
  • Clonal hematopoiesis and inflammation: a link with thrombosis and malignancy

    Tiziano Barbui
    21-07-2022
    https://doi.org/10.4081/btvb.2022.38
    2947
    PDF: 327
  • Cancer-associated ischemic stroke: current knowledge and future directions

    Ronda Lun, Deborah M. Siegal
    16-05-2024
    https://doi.org/10.4081/btvb.2024.117
    2040
    PDF: 630
  • Venous thromboembolism prophylaxis in orthopedic surgery: a narrative review

    Sarah Gallitto, Thomas C. Varkey, Jacob Lahti
    13-12-2024
    https://doi.org/10.4081/btvb.2024.131
    1452
    PDF: 249
  • Endothelial cell dysfunction in cancer: a not-so-innocent bystander

    Betül Ünlü, Neha Joshi, Jamie M. O'Sullivan
    16-05-2024
    https://doi.org/10.4081/btvb.2024.116
    1443
    PDF: 385
  • The clinical usefulness of measuring thrombin generation

    Coenraad H. Hemker
    06-03-2023
    https://doi.org/10.4081/btvb.2023.62
    901
    PDF: 391
  • CS07 | Endothelial dysfunction and impaired angiogenesis in Hermansky-Pudlak syndrome (HPS) type 1: studies with endothelial colony forming cells F. Tondi1, G. Purgatorio1, C. Sgromo2, E. Giglio1, E. Petito1, E. Falcinelli1, G. Guglielmini1, A. Follenzi2, P. Gresele1, L. Bury1*, C. Olgasi3* | *Shared senior authorship; 1Department of Medicine and Surgery, Section of Internal and Cardiovascular Medicine, University of Perugia; 2Department of Health Sciences, School of Medicine, University of Piemonte Orientale, Novara; 3Department of Translational Medicine, School of Medicine, University of Piemonte Orientale, Novara, Italy

    16-09-2025
    https://doi.org/10.4081/btvb.2025.204
    47
  • “Living under the sword of Damocles”: a psychological support project for patients with immune thrombocytopenia and their caregivers

    Giuseppe Auteri, Laura Ricci, Nicola Vianelli, Barbara Lovrencic
    13-03-2025
    https://doi.org/10.4081/btvb.2025.161
    404
    PDF: 136
    Appendix A: 41
    Appendix B: 48
  • A nitric oxide-donor pravastatin hybrid drug exerts antiplatelet and antiatherogenic activity in mice

    Stefania Momi, Giuseppe Guglielmini, Giulia Ciarroca Taranta, Elisa Giglio, Angela Monopoli, Paolo Gresele
    23-05-2022
    https://doi.org/10.4081/btvb.2022.19
    4724
    PDF: 300
  • Cancer complicated by thrombosis and thrombocytopenia: still a therapeutic dilemma

    Yishi Tan, Marc Carrier, Nicola Curry, Michael Desborough, Kathryn Musgrave, Marie Scully, Tzu-Fei Wang, Mari Thomas, Simon J. Stanworth
    16-05-2024
    https://doi.org/10.4081/btvb.2024.115
    833
    PDF: 338
  • Distal deep vein thrombosis: is there a way out of this dark forest?

    Matteo Guarascio, Gerardo Nicola Pititto, Alessia Abenante, Marco Paolo Donadini
    04-09-2024
    https://doi.org/10.4081/btvb.2024.129
    919
    PDF: 283
  • Author's Reply. Da la scheggia rotta usciva insieme parole e sangue: an unusual case of bleeding and the metaphor of a clinical trial

    Giovanni de Gaetano
    05-12-2024
    https://doi.org/10.4081/btvb.2024.163
    622
    PDF: 124
  • Location of metastasis and complications in patients with venous thromboembolism and cancer: a systematic review

    Maria Barca-Hernando, Victor Garcia-Garcia, Luis Jara-Palomares
    16-05-2024
    https://doi.org/10.4081/btvb.2024.114
    587
    PDF: 294
  • Comment on "Apixaban vs. aspirin for stroke prevention in people with subclinical atrial fibrillation and a history of stroke or transient ischemic attack: subgroup analysis of the ARTESiA randomized controlled trial"

    Vittorio Pengo
    01-07-2025
    https://doi.org/10.4081/btvb.2025.179
    595
    PDF: 152
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Vol. 4 No. 3 (2025)
Anticoagulation in obese patients: challenges and strategies
Alice Lipari et al.
18 September 2025
Vol. 4 No. 3 (2025)
The key to fibrinolysis and thrombolysis
Roger Lijnen et al.
9 September 2025
Vol. 4 No. 3 (2025)
In memoriam of Professor Gualtiero Palareti (1943-2025)
Giovanni de Gaetano
25 August 2025

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Bleeding, Thrombosis and Vascular Biology

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