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Bleeding, Thrombosis and Vascular Biology

Editor-in-Chief: Giovanni de Gaetano, Italy | eISSN: 2785-5309

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  • Milvexian and other drugs targeting Factor XI: a new era of anticoagulation?

    Marco P. Donadini, Walter Ageno
    15-04-2022
    https://doi.org/10.4081/btvb.2022.22
    2523
    PDF: 765
  • CO-59 | CONCIZUMAB IN A YOUNG CHILD WITH SEVERE HEMOPHILIA B WITH INHIBITOR: EFFECTIVE BLEED CONTROL AND SAFE HOME MANAGEMENT T. Martini1, B. Borsellino1|2, B. Pollio1 | 1Hemophilia Centre, Immune-Haematology and Transfusion Medicine, University Hospital “Città della Salute e della Scienza”, Torino, Italy; 2Department of Biomedicine and Prevention, PhD in Immunology, Molecular Medicine and Applied Biotechnology, University of Rome Tor Vergata, Roma, Italy

    Tiziano Martini
    14-10-2026
    https://doi.org/10.4081/btvb.2026.669
    28
    PDF: 9
  • PO49 | PROPHYLACTIC ANTICOAGULATION DECISIONS IN HIGH-RISK PATIENTS RECEIVING CANCER-DIRECTED THERAPY: ANALYSIS OF THE VERMONT METHOD J. Barker1, K. Libby1, C. Holmes2, K. Martin2 | 1University of Vermont Health System; 2Department of Medicine, University of Vermont, Burlington, VT, USA

    ICTHIC 2026
    16-04-2026
    https://doi.org/10.4081/btvb.2026.541
    448
    PDF: 105
  • PO28 | Long term effectiveness and safety of venous thromboembolism with fondaparinux: data from the start registry I.M. Palumbo1, E. Valeriani1,2, A. Pannunzio1, S. Marucci3, D. Menichelli1, D. Pastori3,4, P. Pignatelli3 | 1Department of General Surgery and Surgical Specialty, Sapienza University of Roma; 2Department of Infectious Disease, Azienda Ospedaliero-Universitaria Policlinico Umberto I, Roma; 3Department of Clinical Internal, Anaesthesiologic and Cardiovascular Sciences, Sapienza University of Roma, Roma; 4IRCCS NeuRomad, Pozzilli, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.289
    633
    PDF: 12
  • Welcome to AICE and sincere wishes for peace for the new year 2024

    Giovanni de Gaetano
    27-12-2023
    https://doi.org/10.4081/btvb.2023.107
    1709
    PDF: 307
  • CO44 | First interlaboratory validation workshop of immunofluorescence microscopy on the peripheral blood smear for recognizing patients with inherited platelet disorders C. Zaninetti1, L. Bury2, V. Bozzi3, A. Zamora-Cánovas4, K. Althaus5, G. Uzun5, S. Brown6, A. Norman6, D. Faille7, A. Stepanian8, C. Freyer1, L. Kager9, T. Bakchoul5, A. Pecci3, P. Gresele2, T. Thiele1, J. Rivera4, A. Greinacher1 | 1Institut für Immunologie und Transfusionsmedizin, Universitätsmedizin Greifswald, Germany; 2Department of Medicine, Section of Internal and Cardiovascular Medicine, University of Perugia, Italy; 3Department of Internal Medicine, University of Pavia, Italy; General Medicine 1, IRCCS Policlinico San Matteo Foundation, Pavia, Italy; 4Servicio de Hematología, Hospital Universitario Morales Meseguer, Centro Regional de Hemodonacio´n, Universidad de Murcia, Spain; 5Institute for Clinical and Experimental Transfusion Medicine, University Hospital of Tuebingen, Germany; Center for Clinical Transfusion Medicine, Tuebingen, Germany; 6Centre for Children’s Health and Research CCHR, South Brisbane, Australia; 7Laboratoire d’Hématologie, Assistance Publique Hôpitaux de Paris, Hôpital Bichat-Claude-Bernard, Paris, France; 8AP-HP, Service d’Hématologie Biologique, Hôpital Lariboisière, Paris Cité University, Paris, France; 9St. Anna Kinderspital, Universitätsklinik für Kinder- und Jugendheilkunde der Medizinischen Universität Wien, Austria

    22-10-2025
    https://doi.org/10.4081/btvb.2025.250
    587
    PDF: 20
  • PO67 | TARGETED THERAPIES FOR CANCER AND THE RISK OF ARTERIAL AND VENOUS THROMBOEMBOLISM O. Iqbal | Loyola University Stritch School of Medicine, Maywood, IL, USA

    ICTHIC 2026
    16-04-2026
    https://doi.org/10.4081/btvb.2026.556
    470
    PDF: 110
  • The importance of rigorous and engaging scientific communication

    Giovanni de Gaetano
    01-07-2025
    https://doi.org/10.4081/btvb.2025.191
    1540
    PDF: 361
  • CO-25 | MILD HEMOPHILIA A AND JOINT HEALTH IN REAL LIFE: IS THAT AN EMERGING ISSUE? A SINGLE CENTER EXPERIENCE F. Valeri1, G. Murante1, C. Dainese1, M. Capetta1, S. Bergonzi1, R. Pastorino1, F. Bocchi1, B. Bruno2, A. Borchiellini1 | 1Regional Centre for Haemorrhagic and Thrombotic Disease, Hematology Division, AOU Città della Salute e della Scienza, Torino, Italy; 2Division of Hematology, AOU Città della Salute e della Scienza, Department of Molecular Biotechnology and Health sciences, University of Turin, Italy

    Federica Valeri
    14-10-2026
    https://doi.org/10.4081/btvb.2026.635
    25
    PDF: 9
  • OC02 | INCIDENCE AND PREDICTORS OF ARTERIAL THROMBOSIS IN CANCER PATIENTS: RESULTS FROM THE PROSPECTIVE COMPASS-ARTERIAL CANCER ASSOCIATED THROMBOSIS (COMPASS-ARTECAT) STUDY M. Drakopoulou1, I. Diamandoulaki2, P. Baglaridis1, P. Las Casa3, P. Van Dreden4, K. Toutouzas1, G. Gerotziafas4|5 | 1First Department of Cardiology, School of Medicine, National and Kapodistrian University of Athens, Hippokration General Hospital, Athens, Greece; 2Department of Electrical and Computer Engineering, Aristotle University of Thessaloniki, Thessaloniki, Greece; 3Sorbonne University, INSERM UMR_S_938, CRSA, Research Department "Cancer, Vessels, Biology and Therapeutics" (CaVITE), Research Group "Cancer-Angiogenesis-Thrombosis and Haemostasis," Thrombosis Center, University Institute of Cancerology (UIC), Saint Antoine University Hospital Assistance Publique Hôpitaux de Paris (AP-HP) Paris France; 4Diagnostica Stago, clinical research, Gennevilliers, France; 5Center of Translational Research and Education, Department of Pathology and Laboratory Medicine, Loyola University Stritch School of Medicine, Maywood, Ill., USA

    ICTHIC 2026
    16-04-2026
    https://doi.org/10.4081/btvb.2026.486
    502
    PDF: 128
  • The evolving landscape of gene therapy for congenital severe hemophilia: a 2024 state of the art

    Giovanni Di Minno, Gaia Spadarella, Ilenia Lorenza Calcaterra, Giancarlo Castaman, Paolo Simioni, Raimondo De Cristofaro, Cristina Santoro, Flora Peyvandi, Matteo Di Minno
    04-09-2024
    https://doi.org/10.4081/btvb.2024.144
    2075
    PDF: 359
    SUPPLEMENTARY MATERIAL: 217
  • The von Willebrand factor-ADAMTS-13 axis: a two-faced Janus in bleeding and thrombosis

    Stefano Lancellotti, Monica Sacco, Maira Tardugno, Antonietta Ferretti, Raimondo De Cristofaro
    26-04-2022
    https://doi.org/10.4081/btvb.2022.11
    2635
    PDF: 618
  • PO41 | VENOUS THROMBOEMBOLISM IN PERIPHERAL BLOOD STEM CELL COLLECTION. A SINGLE CENTER EXPERIENCE P. Holly1, J. Hudecek1, J. Chudej1, L. Valekova1, I. Plamenova1, E. Flochova1, R. Simonova1, J. Sokol1, J. Stasko1, M. Pietrzykova1|2, E. Vescecikova2 | 1Department of Hematology and Transfusion Medicine, University Hospital in Martin, Martin, Slovakia; 2National Transfusion Service, Martin, Slovakia

    ICTHIC 2026
    16-04-2026
    https://doi.org/10.4081/btvb.2026.535
    502
    PDF: 103
  • CO-78 | REAL-WORLD MANAGEMENT OF ACQUIRED HEMOPHILIA A: FOCUS ON RECOMBINANT PORCINE FVIII AS FIRST-LINE HEMOSTATIC TREATMENT AND LONG-TERM OUTCOMES M. Leotta, A. Strangio, A. Ierardi, R.C. Santoro | Hemophilia, Hemostasis and Thrombosis Centre, Azienda Ospedaliero Universitaria Renato Dulbecco, Catanzaro, Italy

    Marzia Leotta
    14-10-2026
    https://doi.org/10.4081/btvb.2026.688
    20
    PDF: 13
  • PO10 | RISK OF VENOUS THROMBOEMBOLISM IN CANCER PATIENTS WITH CENTRAL VENOUS CATHETERS: RESULTS FROM THE VIENNA CAT-BLED STUDY B. Sunder-Plassmann 1, N, Vladic1, C. Englisch1, F. Moik1|3, V. Sunder-Plassmann2, A. Berghoff2, M. Preusser2, I. Pabinger1, C. Ay1 | 1Division of Hematology and Haemostaseology, Department of Medicine I, Medical University of Vienna; Vienna, Austria; 2Division of Oncology, Department of Medicine I, Medical University of Vienna; Vienna, Austria; 3Division of Oncology, Department of Internal Medicine, Medical University of Graz; Graz, Austria

    ICTHIC 2026
    16-04-2026
    https://doi.org/10.4081/btvb.2026.506
    471
    PDF: 118
  • Prediction and management of recurrent venous thromboembolism in patients with cancer

    Marcello Di Nisio, Tzu-Fei Wang
    16-04-2026
    https://doi.org/10.4081/btvb.2026.419
    876
    PDF: 201
  • CO20 | Coagulation alterations as prognostic indicators in septic patients L. Baratti1, S. N. Pasturenzi1, P. Onorato2, W. Ageno3, F. Cortellaro2, M.P. Donadini2,4 | 1Scuola di Medicina, Università degli Studi dell’Insubria, Varese; 2Pronto Soccorso e Medicina d’Urgenza, Ospedale di Circolo, Varese; 3Dipartimento di Medicina, Università degli Studi di Padova; 4Dipartimento di Medicina e Chirurgia, Università degli Studi dell’Insubria, Varese, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.226
    637
    PDF: 17
  • CO-84 | PARAPROTEIN-DRIVEN ACQUIRED VON WILLEBRAND SYNDROME IN A PATIENT WITH MONOCLONAL GAMMOPATHY OF UNDETERMINED SIGNIFICANCE AND UROTHELIAL CARCINOMA A. Ierardi, A. Strangio, M. Leotta, R.C. Santoro | Hemostasis Unit, AOU Dulbecco, Catanzaro, Italy

    Antonella Ierardi
    14-10-2026
    https://doi.org/10.4081/btvb.2026.694
    19
    PDF: 10
  • Gene transfer in hemophilia B: a big step forward

    Giancarlo Castaman
    17-05-2023
    https://doi.org/10.4081/btvb.2023.70
    1427
    PDF: 649
  • Development of a shared decision-making tool for gene therapy in hemophilia A in Italy

    Giovanni Di Minno, Sarah Bigi, Serena Barello, Enrico Ferri Grazzi, Marco Follino, Maria Francesca Mansueto, Mariasanta Napolitano, Rita Carlotta Santoro, Giancarlo Castaman
    22-06-2026
    https://doi.org/10.4081/btvb.2026.426
    919
    PDF: 131
    SUPPLEMENTARY MATERIAL: 78
  • Stroke in women: anticoagulation in a complicated puzzle

    Francesco Marongiu, Elvira Grandone, Silvia Marongiu, Antonella Mameli, Doris Barcellona
    26-08-2024
    https://doi.org/10.4081/btvb.2024.137
    1748
    PDF: 455
  • CO-57 | NXT007 PROPHYLAXIS IN PEOPLE WITH HEMOPHILIA A WITH OR WITHOUT FACTOR VIII INHIBITORS: COMBINED ANALYSIS OF TWO PHASE I/II MULTIPLE-ASCENDING-DOSE STUDIES M.E. Mancuso1|2, M. Shima3, J.M. Staber4, Y.C. Chen5, F.J. López-Jaime6, M.C. Shen7, G. Ventriglia8, M. Takeyama9, C. Schmitt8, Y.S. Park10, A. Kiialainen8, N. Mizuno11, M. Niggli8, T. Miyake11, D. Matino12, T. Saito11, V. Jiménez-Yuste13, R. Kobayashi11, D. Hart14, K. Nogami15 | 1Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milano, Italy; 2Center for Thrombosis and Hemorrhagic Diseases, IRCCS Humanitas Research Hospital, Rozzano, Milano, Italy; 3Thrombosis and Hemostasis Research Center, Nara Medical University, Kashihara, Nara, Japan; 4Stead Family Department of Pediatrics, Carver College of Medicine, University of Iowa, Iowa City, USA; 5Hemophilia Care and Research Center, Tri-Service General Hospital, National Defense Medical University, Taipei, Taiwan; 6Servicio de Hematología, Hospital Universitario Regional de Málaga / Instituto de Investigación Biomédica de Málaga (IBIMA), Málaga, Spain; 7Department of Internal Medicine, Changhua Christian Hospital, Changhua, Taiwan; 8F. Hoffmann-La Roche Ltd, Basel, Switzerland; 9Division of Hemophilia, National Hospital Organization, Osaka National Hospital, Osaka, Japan; 10Department of Pediatrics, Kyung Hee University Hospital at Gangdong, Seoul, South Korea; 11Chugai Pharmaceutical Co., Ltd, Tokyo, Japan; 12McMaster University, Hamilton, Ontario, Canada; 13La Paz University Hospital-IdiPAZ, Autónoma University, Madrid, Spain; 14Roche Products Ltd, Welwyn Garden City, UK; 15Department of Pediatrics, Nara Medical University, Kashihara, Nara, Japan

    Maria Elisa Mancuso
    14-10-2026
    https://doi.org/10.4081/btvb.2026.667
    22
    PDF: 14
  • PO25 | Baseline thrombin generation test does not predict thrombotic events in acute leukemia: a monocentric prospective study M. Biglietto, R. Mormile, M.L. Bisegna, A. Laganà, A. L. Faccini, A. Papa, E. Baldacci, C. Santoro, M.S. De Propris, A. Chistolini | Hematology, Department of Translational and Precision Medicine Sapienza University of Roma, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.286
    646
    PDF: 12
  • CO01 | Statin therapy for the prevention of venous thromboembolism in cancer patients: a systematic review and meta-analysis F. Catalani, R. Del Giorno, R. Canevascini, W. Ageno, L. Gabutti, G. Prouse, L. Giovannacci | Ospedale Regionale di Bellinzona, Switzerland.

    22-10-2025
    https://doi.org/10.4081/btvb.2025.199
    695
    PDF: 14
  • Personalized bleeding risk assessment for atrial fibrillation patients on direct oral anticoagulants: the DOAC score

    Paolo Prandoni
    11-10-2023
    https://doi.org/10.4081/btvb.2023.97
    2128
    PDF: 459
  • OC11 | COMPLEXITIES IN MANAGING ANTITHROMBOTIC THERAPY IN PATIENTS WITH CANCER APPROACHING END-OF-LIFE: A MIXED METHOD INTEGRATION USING JOINT DISPLAY ANALYSIS E. Baddeley1, L. Van’t Walderveen2, H. Enggaard3, M. Søgaard4, D. Abbel2, S. Cannegieter2, M. Edwards1, C. Font5, J. Goedegebuur2, F.A. Klok2, K.J. Lifford1, I. Mahé6, S.P. Mooijaart2, S.I.R. Noble1, M. Pearson7, K. Seddon1, S. Sivell1, S. Szmit8, S Trompet2, A.A. Højen4 | 1Cardiff University, Cardiff, UK; 2Leiden University Medical Center, Leiden, The Netherlands; 3Aalborg University Hospital, Aalborg, Denmark; 4Aalborg University and Aalborg University Hospital, Aalborg, Denmark; 5Hospital Clinic Barcelona, Barcelona, Spain; 6Paris Cité Université, Paris, France; 7Hull York Medical School, Hull, UK; 8Centre of Postgraduate Medical Education, Warsaw, Poland

    ICTHIC 2026
    16-04-2026
    https://doi.org/10.4081/btvb.2026.494
    443
    PDF: 107
  • Thrombosis and hemostasis at the University of Padua: a reappraisal on the occasion of its 800th year of history

    Paolo Simioni, Vittorio Pengo, Paolo Prandoni
    07-11-2022
    https://doi.org/10.4081/btvb.2022.52
    2795
    PDF: 446
  • PO80 | Heparin-induced thrombocytopenia: a monocentric experience with danaparoid L. D’Innocenzo, S. Sorrentino, M. De Siati, A. Ferretti, E. De Candia | Unit of Haemostasis and Thrombosis Diseases, Fondazione Policlinico Universitario A. Gemelli, IRCCS, Roma, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.349
    691
    PDF: 12
  • PO36 | Venous stenting for symptomatic iliac thrombosis: five-years experience of single center I. Nichele1, G. Marchesini1, L. Boi2, G. Carli1, A. Tosetto1 | 1Hemophilia and Thrombosis Center, Hematology Department, S. Bortolo Hospital, Vicenza; 2Radiology Department, Ospedale Ca’ Foncello, Treviso, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.299
    621
    PDF: 24
  • CO08 | The utility of urine qualitative assessment for direct oral anticoagulants in routine clinical practice F. Schieppati1,2, P. Gomez-Rosas1,3, C. Ambaglio1, V. Brusegan1, Oc. Cretu1,2, E. Galimberti1, F. Zunino1, L. Barcella1, J. Harenberg4,5, A. Falanga1,2, M. Marchetti1,2 | 1Immunohematology and Transfusion Medicine, Hospital Papa Giovanni XXIII, Bergamo, Italy; 2School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy; 3Maastricht University Medical Center, Cardiovascular Research Institute Maastricht, Maastricht, The Netherlands; 4Ruprecht Karls University of Heidelberg, Germany; 5Germany DOASENSE GmbH, Heidelberg, Germany

    22-10-2025
    https://doi.org/10.4081/btvb.2025.212
    740
    PDF: 19
  • ReDIP, the Italian network for the diagnosis of congenital platelet function disorders

    Marco Cattaneo, Claudia Ghali, Mariangela Scavone
    22-04-2024
    https://doi.org/10.4081/btvb.2024.134
    843
    PDF: 286
  • CO-83 | ACQUIRED FACTOR V DEFICIENCY IN A HIGH-THROMBOTIC-RISK PATIENT: DIAGNOSTIC DILEMMA AND SUCCESSFUL MANAGEMENT G. Gazzelli1, L. Banov1, Y. Azzanelli1, C. Vernarecci1, F. Marotta1, F. Giacopelli1, E. Cenni2, V. Agostini2, A.C. Molinari1 | 1IRCCS Istituto Giannina Gaslini, Italy; 2IRCSS AOM S. Martino, Genova, Italy

    Angelo Claudio Molinari
    14-10-2026
    https://doi.org/10.4081/btvb.2026.693
    29
    PDF: 17
  • Medicine at the crossroads of science, compassion and ethical responsibility

    Maria Benedetta Donati
    12-12-2025
    https://doi.org/10.4081/btvb.2025.423
    628
    PDF: 106
    HTML: 118
  • PO07 | Liver transplant in a case of congenital afibrinogenemia G. Murante1,2,3, S. Bergonzi1,2,3, C. Sella1,2,3, F. Valeri1,2, C. Dainese1,2, A. Valpreda4, R. Pastorino1,3, R. Romagnoli5, D. Patrono5, D. Cussa5, S. Martini6, B. Bruno2,3, A. Borchiellini1,2 | 1Regional Centre for Hemorrhagic and Thrombotic Diseases, AOU Città della Salute e della Scienza, Torino; 2Division of Hematology, AOU Città della Salute e della Scienza, University of Turin; 3Department of Molecular Biotechnology and Health Sciences, University of Turin; 4Central Laboratory Baldi and Riberi, AOU Città della Salute e della Scienza, Torino; 5General Surgery 2U - Liver Transplant Center, Molinette Hospital, AOU Città della Salute e della Scienza, Torino; 6SSD Hepatic insufficiency and Liver Transplant, AOU Città della Salute e della Scienza, Torino, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.269
    576
    PDF: 15
  • “Living under the sword of Damocles”: a psychological support project for patients with immune thrombocytopenia and their caregivers

    Giuseppe Auteri, Laura Ricci, Nicola Vianelli, Barbara Lovrencic
    13-03-2025
    https://doi.org/10.4081/btvb.2025.161
    991
    PDF: 371
    Appendix A: 139
    Appendix B: 142
  • A contribution from Umberto Veronesi Foundation

    Chiara Tonelli
    04-04-2023
    https://doi.org/10.4081/btvb.2023.74
    687
    PDF: 397
  • CO-69 | IN VITRO CORRECTION OF SEVERE FACTOR V DEFICIENCY USING A NOVEL PLASMA-DERIVED FACTOR V CONCENTRATE: A WHOLE BLOOD THROMBIN GENERATION STUDY C. Bulato1, E. Campello1, L. Spiezia1, B. Serena1, S. Toffanin1, C. Simion1, A. Caricasole2, M. Sotgiu2, A. Salvatore2, F. Pierantoni2, T.M. Hackeng3|4, H.M.H. Spronk3|4, P. Simioni1 | 1First Chair of Internal Medicine, Thrombotic and Haemorrhagic Diseases Unit and Haemophilia Centre, Department of Medicine, Padova University Hospital, Padova, Italy; 2Kedrion SpA, Barga Lucca, Italy; 3Coagulation Profile B.V., Maastricht, Netherland; 4Department of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, Netherland

    Cristiana Bulato
    14-10-2026
    https://doi.org/10.4081/btvb.2026.679
    22
    PDF: 8
  • CO-23 | PERIOPERATIVE MANAGEMENT OF MILD-TO-MODERATE HEMOPHILIA: A COMPARATIVE STUDY OF EXTENDED HALF-LIFE VERSUS STANDARD HALF-LIFE CONCENTRATES ON CLINICAL OUTCOMES AND FACTOR CONSUMPTION M. Capetta1|2|3, F. Valeri1|2, C. Dainese1|2, S. Bergonzi1|2|3, G. Murante1|2|3, A. Valpreda4, R. Pastorino1|3, F. Bocchi1|3, B. Bruno2|3, A. Borchiellini1|2 | 1Regional Centre for Hemorrhagic and Thrombotic Diseases, AOU Città della Salute e della Scienza, Torino, Italy; 2Division of Hematology, AOU Città della Salute e della Scienza, University of Turin, Italy; 3Department of Molecular Biotechnology and Health Sciences, University of Turin, Italy; 4Central Laboratory Baldi and Riberi, AOU Città della Salute e della Scienza, University of Turin, Italy

    Matilde Capetta
    14-10-2026
    https://doi.org/10.4081/btvb.2026.633
    27
    PDF: 9
  • CO31 | Immune system profiling in FVIII-treated and emicizumab-treated pediatric HA patients A. Cottonaro1, S. Akula1, B. Pollio2, I. Ricca2, T. Martini2, J. Agnelli Giacchello3, P. Sciancalepore3, R. Santi3, A. Follenzi1,3, S. Merlin1 | 1Università del Piemonte Orientale, Health Sciences, Novara; 2A.O. Città della Salute e della Scienza, SIMT Immunohematology and Transfusion Medicine Service, Diagnostic Department, Torino; 3Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo, Alessandria, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.238
    636
    PDF: 15
  • Distal deep vein thrombosis: is there a way out of this dark forest?

    Matteo Guarascio, Gerardo Nicola Pititto, Alessia Abenante, Marco Paolo Donadini
    04-09-2024
    https://doi.org/10.4081/btvb.2024.129
    1618
    PDF: 481
  • Safety and efficacy of treatment with vitamin K antagonists in patients managed in a network of anticoagulation services or as routine general care

    Gianfranco De Girolamo, Luca Sarti, Sonia Cecoli, Karin Bonora, Chiara Ajolfi, Francesco Bellelli, Valeria Coluccio, Gualtiero Palareti, Marco Marietta
    15-04-2022
    https://doi.org/10.4081/btvb.2022.9
    1151
    PDF: 387
    Supplementary Files: 163
  • Hemophilia-free mind: a call to action

    Tiziano Martini, Chiara Gorio, Cristina Dainese, Rita Carlotta Santoro, Giancarlo Castaman
    10-03-2026
    https://doi.org/10.4081/btvb.2026.465
    536
    PDF: 126
  • Perioperative management of patients taking direct oral anticoagulants: challenges in high-bleed-risk surgery and neuraxial anesthesia

    Maria P. Ntalouka, Eleni M. Arnaoutoglou, James D. Douketis
    28-08-2026
    https://doi.org/10.4081/btvb.2026.471
    469
    PDF: 233
  • CO-62 | ACCESS TO ULTRA-LONG HALF-LIFE FACTOR VIII AS THE DEFINITIVE MOTIVATION FOR IMMUNE TOLERANCE INDUCTION IN THE ERA OF NON-REPLACEMENT THERAPIES B. Borsellino1, T. Martini1, I. Ricca2, C. Linari3, B. Pollio1 | 1Paediatric Haemophilia Centre, Immune-Haematology and Transfusion Medicine, University Hospital "Città della Salute e della Scienza", Torino, Italy; 2Transfusion Medicine, Ivrea Hospital, Ivrea, Italy; 3Department of Laboratory Medicine, Azienda Ospedaliera Universitaria Città della Salute e della Scienza, Turin, Italy

    Beatrice Borsellino
    14-10-2026
    https://doi.org/10.4081/btvb.2026.672
    24
    PDF: 9
  • CO-12 | BEYOND CLOTTING FACTORS: NURSING AS A CORNERSTONE OF LIFELONG HEMOPHILIA CARE M.V. Puliga1, C. Manzi2, A. Besagni3, S. Linari1, C. Carulli4, M. Morfini5 | 1SODc Malattie Emorragiche e della Coagulazione, AOU Careggi, Firenze, Italy; 2SSD Malattie Emorragiche Congenite, IRCCS Policlinico Sant'Orsola, Bologna, Italy; 3Indipendente, Italy; 4Clinica Ortopedica, Università di Firenze, SOD Ortopedia, AOU Careggi, Firenze, Italy; 5Associazione Italiana Centri Emofilia, AICE, Milano, Italy

    Maria-Virginia Puliga
    14-10-2026
    https://doi.org/10.4081/btvb.2026.622
    70
    PDF: 10
  • PO35 | Cerebral veins thrombosis in patients with and without myeloproliferative neoplasm: a real life retrospective monocentric study I. Bertozzi, M.T. Sartori, M. Zerbinati, G. Libralon, A. Galbiati, P. Simioni | First Medical Clinic, Department of Medicine - DIMED, Università degli Studi di Padova, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.298
    593
    PDF: 24
  • PO27 | URINE QUALITATIVE ASSESSMENT OF DIRECT ORAL ANTICOAGULANTS IN ROUTINE CLINICAL PRACTICE F. Schieppati1|2, P. Gomez-Rosas1|3, C. Ambaglio1, V. Brusegan1, O.C. Cretu1, E. Galimberti1, F. Zunino1, L. Barcella1, J. Harenberg4|5, A. Falanga1|2, M. Marchetti1|2 | 1Immunohematology and Transfusion Medicine, Hospital Papa Giovanni XXIII, Bergamo, Italy; 2School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy; 3Maastricht University Medical Center, Cardiovascular Research Institute Maastricht, Maastricht, The Netherlands; 4Ruprecht Karls University of Heidelberg, Heidelberg, Germany; 5DOASENSE GmbH, Heidelberg, Germany

    ICTHIC 2026
    16-04-2026
    https://doi.org/10.4081/btvb.2026.522
    428
    PDF: 96
  • PO53 | Effectiveness and safety of DOACS in patients with renal transplantation A. Ierardi, A. Strangio, M. Leotta, R C. Santoro | UO Emofilia, Emostasi e Trombosi, AOU Renato Dulbecco, Catanzaro, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.322
    637
    PDF: 17
  • PO05 | Intensive FVIII replacement in haemophilia patients with hypertrophic synovium: a randomized study I.L. Calcaterra1, E. Baldacci2, R. Marino3, F. Valeri4, R.C. Santoro5, G. Pasta6, C. Martinoli7, M. Di Minno1 | 1Department of Clinical Medicine and Surgery, Federico II University, Naples; 2Haematology, University Hospital Policlinico Umberto I, Roma; 3Haemophilia Center and thrombosis, Policlinico, Bari; 4Regional Centre for Haemorrhagic and Thrombotic Diseases, AOU Città Della Salute e Della Scienza; Turin; 5Centre for Hemorrhagic and Thrombotic Disorders, Pugliese Ciaccio Hospital, Catanzaro; 6Fondazione IRCCS San Matteo Hospital, Pavia; 7Department of Health Science DISSAL, University of Genoa, Unit of Radiology and IRCCS San Martino Hospital, Genoa, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.267
    590
    PDF: 17
  • ERRATUM - Neurovascular protective effects of nutritional interventions in ischemic brain injury

    Pooja Mishra, Geetika Mehta, Suyash Sharma, Rashmi Tripathi, Monika Sachdeva
    15-05-2026
    https://doi.org/10.4081/btvb.2026.569
    517
    PDF: 115
  • Hormones, cancer, and thrombosis: sex-specific mechanisms at the interface of hemostasis and vascular biology

    Elvira Grandone, Giovanni Tiscia
    16-04-2026
    https://doi.org/10.4081/btvb.2026.435
    586
    PDF: 192
  • PO87 | Intravascular leiomyomatosis extending to the right atrium: a case report with a multidisciplinary management M. Iorio1,2, C. Cavallaro1,2, E. Butera1,2, R. Talerico1,2, A. Gasbarrini2,3, R. Pola1,2 | 1Department of Aging, Orthopedic, and Rheumatologic Sciences, Agostino Gemelli Polyclinic Foundation Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma; 2Università Cattolica del Sacro Cuore, Roma; 3Department of Medical and Surgical Sciences, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.357
    625
    PDF: 15
  • CO30 | Joint prosthetic surgery in patients with hemophilia A: clinical-functional outcomes and quality of life E. Zanon1, A. Napolitano1, A. Berizzi2, P. Simioni1 | 1Haemophilia Center, First Chair of Internal Medicine, Department of Medicine, University-Hospital of Padua Medical School, Padua; 2Orthopedics and Traumatology Unit, University-Hospital of Padua Medical School, Padua, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.236
    686
    PDF: 31
  • Recent advances in classic heparin-induced thrombocytopenia (HIT), autoimmune HIT, spontaneous HIT, and vaccine-induced immune thrombotic thrombocytopenia

    Bianca Clerici, Mariangela Scavone, Gian Marco Podda
    20-06-2024
    https://doi.org/10.4081/btvb.2024.127
    2846
    PDF: 827
  • CO-55 | DEVELOPMENT OF ENGINEERED LONG-ACTING BYPASSING FX VIA ALBUMIN FUSION FOR HEMOPHILIA WITH INHIBITORS A. Martucci1, R. Tarantino1, K.H. Aaen2, M. Pinotti1, J.T. Andersen2, A. Branchini1 | 1Department of Life Sciences and Biotechnology, University of Ferrara, Ferrara, Italy; 2Institute of Clinical Medicine, Department of Pharmacology, University of Oslo, Norway

    Alessandro Martucci
    14-10-2026
    https://doi.org/10.4081/btvb.2026.665
    20
    PDF: 10
  • PO22 | Early detection and management of PICC-related thrombosis in oncohematologic patients through serial ultrasound monitoring: a prospective observational study S. Laurenti, M. Schneeberger, G. Rosati, A. Pozzi, M. Padrini, R. Vacchelli, A. Morotti | University of Turin, AUO San Luigi Gonzaga, Orbassano (TO), Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.282
    633
    PDF: 25
  • Hemostasis and the kidney: an unforeseen initial opportunity to create a small research group that grew into an institute

    Carlamaria Zoja, Ariela Benigni, Giuseppe Remuzzi
    30-06-2025
    https://doi.org/10.4081/btvb.2025.190
    756
    PDF: 236
    Supplementary: 97
  • Clinical and radiological characteristics of cerebral vein thrombosis: a retrospective study

    Mosaad Almegren
    12-10-2023
    https://doi.org/10.4081/btvb.2023.85
    1146
    PDF: 351
  • Inflammation and hemostatic system: a selection of involved clinical disorders

    Francesco Marongiu, Antonella Mameli, Silvia Marongiu, Doris Barcellona
    28-08-2026
    https://doi.org/10.4081/btvb.2026.474
    369
    PDF: 132
  • OC06 | PRIMARY THROMBOPROPHYLAXIS IN ADVANCED PANCREATIC DUCTAL ADENOCARCINOMA UNDERGOING SYSTEMIC ANTICANCER TREATMENT: A CANCER-CENTER COHORT STUDY ON CLINICAL PRACTICE AND OUTCOMES F. Haque1|2, A. Adekeye1|2, Z. Mohtashim2, K. Page1, M. Goodman1, A. Maraveyas 1|2 | 1Hull University Teaching Hospital NHS Trust, UK; 2Hull York Medical School, UK

    ICTHIC 2026
    16-04-2026
    https://doi.org/10.4081/btvb.2026.490
    471
    PDF: 104
  • PO01 | Diagnosis of inherited platelet function disorders by platelet aggregometry using a fully automated coagulation analyzer E. Falcinelli1, A.M. Mezzasoma1, L. Bury1, R. Martini1, I. Tano1, A. Rechner2, P. Gresele1 | 1Department of Medicine, Section of Internal and Cardiovascular Medicine, University of Perugia, Italy; 2Sysmex Europe, Germany

    22-10-2025
    https://doi.org/10.4081/btvb.2025.311
    646
    PDF: 15
  • CO-61 | REAL-WORLD IMPLEMENTATION OF GENE THERAPY FOR HEMOPHILIA: A SHARED PATHWAY AMONG HEALTHCARE AUTHORITY, SPECIALIST CENTERS AND PATIENT ORGANIZATIONS IN THE EMILIA-ROMAGNA REGION A. Coppola1, L. Valdrè2, C. Biasoli3, E. Ferri Grazzi4, E. Rozzi5, M. Volta5, R. Giroldini6, A. Tagliaferri1 | 1SSD Centro Hub Emofilia e Malattie Emorragiche Congenite, Azienda Ospedaliero-Universitaria di Parma, Italy; 2SSD Malattie Emorragiche Congenite, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Italy; 3SSI Presa in Carico delle Malattie Emorragiche e Tromboemboliche, AUSL Romagna, Ospedale Bufalini, Cesena, Italy; 4FEDRED, Federazione delle Associazioni Emofilici della Regione Emilia Romagna, Italy; 5Servizio Assistenza Ospedaliera, Malattie Rare, Direzione Generale Cura della Persona, Salute e Welfare, Regione Emilia Romagna, Italy; 6Area Governo del Farmaco e Dispositivi Medici, Direzione Generale Cura della Persona, Salute e Welfare, Regione Emilia Romagna, Italy

    Antonio Coppola
    14-10-2026
    https://doi.org/10.4081/btvb.2026.671
    20
    PDF: 9
  • CO-11 | MAPPING THE COMPETENCIES OF NURSES IN ITALIAN HEMOPHILIA CENTERS: CURRENT STATUS AND PERSPECTIVES FOR THE IDENTIFICATION OF NURSE-SENSITIVE OUTCOMES M.V. Puliga1, A.C. Ferrini2, C. Manzi3, D. Meneghini4, E. Tosi4, P. Berto5, M. Amelotti-Botta6, E. Quercio6, M.E. Mancuso7, R.C. Santoro8 | 1SODc Malattie Emorragiche e della Coagulazione, AOU Careggi, Firenze, Italy; 2SSI Malattie Emorragiche e Tromboemboliche, Osp. Bufalini, Cesena, Italy; 3SSD Malattie Emorragiche Congenite, IRCCS Policlinico Sant'Orsola, Bologna, Italy; 4Centro Emofilia e UOC Medicina Trasfusionale, AOU Integrata, Verona, Italy; 5Centro Emofilia Hub, AO di Padova, Italy; 6SSD Emostasi e Coordinamento Malattie Rare, AO SS. Antonio e Biagio, Alessandria, Italy; 7UOC Centro Trombosi e Malattie Emorragiche, IRCCS Humanitas Research Hospital, Rozzano, Milano, Italy; 8UOD Emofilia, Emostasi e Trombosi, AOU Renato Dulbecco, Catanzaro, Italy

    Maria-Virginia Puliga
    14-10-2026
    https://doi.org/10.4081/btvb.2026.621
    66
    PDF: 10
  • PO51 | MECHANISTIC POPULATION PHARMACOKINETIC/PHARMACODYNAMIC MODELING OF FACTOR XI-TARGETING MONOCLONAL ANTIBODIES SUPPORTS DURABLE ANTICOAGULANT COVERAGE AND TRANSLATIONAL DOSE AND REGIMEN SELECTION O. Milberg1, H. Abdallah1, R.K. Lokken2, R. Dingman1, K.A. Meagher1, M.E. Burczynski1, E. Marin1, A.P. Kithcart1, D. E. Gutstein1 | 1Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA; 2Allucent, Cary, NC, USA

    ICTHIC 2026
    16-04-2026
    https://doi.org/10.4081/btvb.2026.543
    503
    PDF: 118
  • PO76 | Thrombosis associated with midline in autoimmune patient: a case report on the use of apixaban in a real-world setting M.V. Cherchi, M. Anedda, S. Che, M. Vacca, M. Caboni, M. Mantega | Department of Internal Medicine, ASL Sulcis, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.345
    589
    PDF: 26
  • BEST-04 | MAJOR ORTHOPEDIC SURGERY WITH EMICIZUMAB: A SERIES OF 22 PATIENTS (40 PROCEDURES) WITH A MID-TERM FOLLOW-UP G. Daniele1, C. Carulli1, S. Linari2, L. Pieri2, G. Castaman2 | 1Clinica Ortopedica, Azienda Ospedaliero-Universitaria Careggi, Università degli Studi di Firenze, Italy; 2Centro Malattie Emorragiche e della Coagulazione, Azienda Ospedaliero-Universitaria Careggi, Firenze, Italy

    Giovanna Daniele
    14-10-2026
    https://doi.org/10.4081/btvb.2026.604
    64
    PDF: 10
  • PO51 | Thrombocythemia associated with a non-canonical JAK2 mutation: a case report G. Rosati, A. Pozzi, M. Padrini, S. Laurenti, G. Ferrari, R.M. Medici, C. Barale, I. Russo, A. Morotti | University of Turin, AUO San Luigi Gonzaga, Orbassano (TO), Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.320
    746
    PDF: 14
  • CO48 | Gynecological involvement in females with congenital plasminogen deficiency type 1 C. Dalla Porta1,2, M.T. Sartori1, G. Saggiorato1, I. Cortella1, S.A. Malerba1,3, P. Simioni1 | 1First Medical Clinic, Department of Medicine - DIMED, Università degli Studi di Padova; 2Department of Medicine, Casa di Cura Villa Maria, Padova; 3Medicina Generale, Ospedale dell’Angelo, Mestre, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.258
    559
    PDF: 18
  • Pathways for lower extremity superficial vein thrombosis management in an academic medical center

    Gisoo Imani, Aaron Wilson, Sara Vazquez, Daniel M. Witt
    24-03-2025
    https://doi.org/10.4081/btvb.2025.155
    870
    PDF: 265
  • Science in Ukraine is “bleeding”

    Giovanni de Gaetano
    14-03-2023
    https://doi.org/10.4081/btvb.2023.69
    1272
    PDF: 384
  • Factor XI inhibitors: a new option for the prevention and treatment of cancer-associated thrombosis

    Marcello Di Nisio, Matteo Candeloro, Nicola Potere, Ettore Porreca, Jeffrey I. Weitz
    16-05-2024
    https://doi.org/10.4081/btvb.2024.118
    1895
    PDF: 1300
  • CO-53 | LIVER FIBROSIS, STEATOSIS AND SUBCLINICAL ATHEROSCLEROSIS IN PATIENTS WITH HEMOPHILIA: A CROSS-SECTIONAL STUDY C. Simion1|2, B. Stocco1|2, I. Condonato1|2, E. Dalla Porta1|2, A. Napolitano1|2, E. Zanon1|2, L. Fabris1, L. Spiezia1|2, P. Simioni1|2 | 1First Chair of Internal Medicine and Thrombotic and Haemorrhagic Diseases Unit, Department of Medicine, Padova University Hospital, Italy; 2Hemophilia Center, Padova University Hospital, Italy

    Chiara Simion
    14-10-2026
    https://doi.org/10.4081/btvb.2026.663
    22
    PDF: 15
  • PO20 | Impact of endovascular treatment on functional outcome in ischemic stroke: a real-world retrospective study M.G. Mosconi1, G. Maraziti1, M. Paciaroni2, J. Fagotti3, V. Caso1 | 1Azienda Ospedaliera di Perugia; 2Università degli Studi di Ferrara; 3Ospedale San Giovanni Battista, Foligno (PG), Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.280
    652
    PDF: 16
  • The evolution of hemostasis genetics: from monogenic disorders to complex traits. A historical perspective

    Augusto Di Castelnuovo
    01-07-2025
    https://doi.org/10.4081/btvb.2025.184
    1588
    PDF: 349
  • Addressing some challenges of congenital fibrinogen disorders in 2023 and beyond

    Cristina Santoro, Alessandro Casini
    03-08-2023
    https://doi.org/10.4081/btvb.2023.75
    1730
    PDF: 593
  • PO95 | Idiopathic thrombocytopenic purpura in tuberculosis M. Shani | Università di Medicina Tirana, Albania

    22-10-2025
    https://doi.org/10.4081/btvb.2025.365
    638
    PDF: 15
  • Pharmacokinetic interactions between anticancer drugs and direct oral anticoagulants: clinical implications for safe anticoagulation

    Tzu-Fei Wang, Kristen M. Sanfilippo, Marc Carrier
    16-04-2026
    https://doi.org/10.4081/btvb.2026.434
    360
    PDF: 183
  • PO29 | Quality of anticoagulation as a predictor of early left ventricular thrombosis resolution: a retrospective cohort study A. Pannunzio1, I.M. Palumbo1, M.P. Donadini2, D. Santagata2, W. Ageno2, F. Dragoni3, A. Chistolini3, C. Becattini4, K. Satula4, D. Menichelli1, D. Pastori1, P. Pignatelli5, E. Valeriani1 | 1Department of General Surgery and Surgical Specialty Paride Stefanini, Sapienza University of Roma; 2Department of Medicine and Surgery, University of Insubria, Varese; 3Hematology, Department of Translational and Precision Medicine, Sapienza University of Roma; 4Internal Vascular and Emergency Medicine - Stroke Unit, University of Perugia; 5Department of Clinical Internal, Anesthesiological and Cardiovascular Sciences, Sapienza University of Roma, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.290
    602
    PDF: 14
  • CO03 | Early discharge and home treatment of low-risk pulmonary embolism: a cohort study E. Ruggeri1, L. Vulcano1, W. Ageno2, F. Cortellaro3, M.P. Donadini3,4 | 1Scuola di Medicina, Università degli Studi dell’Insubria, Varese; 2Dipartimento di Medicina, Università degli Studi di Padova; 3Pronto Soccorso e Medicina d’Urgenza, Ospedale di Circolo, ASST Sette Laghi, Varese; 4Dipartimento di Medicina e Chirurgia, Università degli Studi dell’Insubria, Varese, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.208
    662
    PDF: 23
  • Tailored therapy with turoctocog alfa pegol according to patient’s lifestyle and hemorrhagic phenotype: from clinical trial to real-life

    Ilaria Nichele, Giuseppe Carli, Alberto Tosetto
    22-04-2024
    https://doi.org/10.4081/btvb.2024.104
    1073
    PDF: 378
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Bleeding, Thrombosis and Vascular Biology

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