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  Anticoagulation in obese patients: challenges and strategies

  Alice Lipari, Esmeralda Capristo, Antonietta Ferretti, Erica De Candia

  18-09-2025

  https://doi.org/10.4081/btvb.2025.174

  2037

  PDF: 537

  HTML: 306

  XML: 191

• CO076 | ASSOCIATION OF MATRIX METALLOPROTEINASE 2 PLASMA LEVELS WITH CARDIOVASCULAR EVENTS IN PATIENTS WITH ATRIAL FIBRILLATION: A NESTED CASE CONTROL STUDY FROM THE ATHERO-AF COHORT D. Menichelli¹, E. Falcinelli², P. Pignatelli³, R. Carnevale^4|5, A. D’Amico⁴, F. Violi², P. Gresele², D. Pastori^4|5, F. Paciullo⁶ | ¹Dip. di Chirurgia Generale e Specialità Chirurgiche Paride Stefanini, Università La Sapienza, Roma, Italy; ²Dip. di Medicina e Chirurgia, Sez. di Medicina Interna Cardiovascolare, Università degli Studi di Perugia, Italy; ³Dip. di Scienze Medico-Chirurgiche e Biotecnologie, Università La Sapienza, Latina, Italy; ⁴IRCCS Neuromed, Pozzilli, Isernia, Italy; ⁵Dip. di Scienze Mediche e Cardiovascolari, Università La Sapienza, Roma, Italy; ⁶Fac. di Medicina e Chirurgia , Vita-Salute San Raffaele University, Milano, Italy

  Francesco Paciullo

  26-10-2026

  https://doi.org/10.4081/btvb.2026.778

  21

  PDF: 8

• PO142 | CROSS-TALK BETWEEN HEART AND BRAIN IN ATRIAL FIBRILLATION: ASSOCIATIONS BETWEEN CARDIAC REMODELING AND CEREBROVASCULAR LESION BURDEN IN THE STRAT-AF STUDY F. Alfano^1|2, C. Barbato³, M. Berteotti^1|2, L. Cosco^1|2, A. Sammartino^1|2, G. Guidotti^1|2, V. Liberati^1|2, G. Iula^1|2, M. Papi^1|2, A. Fidanzati^1|2, B. Formelli³, E. Barucci³, G. Salti³, F. Fratini³, T. Lo Castro³, C. Parenti⁴, E. Fainardi^2|5, A. Di Carlo⁴, E. Salvadori¹, A. Poggesi^1|3, R. Marcucci^1|2 | ¹Department of Experimental and Clinical Medicine, University of Florence, Firenze, Italy; ²Center for Atherothrombotic Diseases, Careggi University Hospital, Firenze, Italy; ³NEUROFARBA Department, Neuroscience Section, University of Florence, Firenze, Italy; ⁴Institute of Neuroscience, Italian National Research Council, Sesto Fiorentino, Italy; ⁵Neuroradiology Unit, Careggi University Hospital, Firenze, Italy

  Francesco Alfano

  26-10-2026

  https://doi.org/10.4081/btvb.2026.958

  22

  PDF: 8
• 

  Management of anticoagulation in atrial fibrillation patients in Italy: insight from the Atrial Fibrillation-Survey on Anticoagulated Patients Register (AF-START)

  Daniela Poli, Walter Ageno, Emilia Antonucci, Salvatore Bradamante, Eugenio Bucherini, Paolo Chiarugi, Antonio Chistolini, Benilde Cosmi, Anna Falanga, Antonio Insana, Domenico Lione, Rosa Maria Lombardi, Giuseppe Malcangi, Rossella Marcucci, Giuliana Martini, Lucilla Masciocco, Carmelo Paparo, Daniele Pastori, Simona Pedrini, Vittorio Pengo, Pasquale Pignatelli, Andrea Toma, Sophie Testa, Gualtiero Palareti

  27-06-2023

  https://doi.org/10.4081/btvb.2023.84

  2164

  PDF: 648

  Supplementary File: 289
• 

  Executive summary of the SISET position paper on the management of antithrombotic therapy in left ventricular thrombus

  Emanuele Valeriani, Arianna Pannunzio, Danilo Menichelli, Domenico Prisco, Walter Ageno, Daniele Pastori, Pasquale Pignatelli

  16-12-2025

  https://doi.org/10.4081/btvb.2025.401

  472

  PDF: 138

  HTML: 113
• 

  Management of atrial fibrillation: a practical and useful synopsis of last guidelines

  Gualtiero Palareti

  24-02-2025

  https://doi.org/10.4081/btvb.2025.168

  1483

  PDF: 206

• PO149 | MANAGEMENT OF ANTITHROMBOTIC THERAPY IN A PATIENT WITH HEMOPHILIA C AND ATRIAL FIBRILLATION E. Marrone¹, G. Ruggiero², E. Cimino³, P. Conca³, C. Miele⁴, F. Gallucci¹, A. Abate¹, C. Romano¹, D. Leosco², U. Valentino¹ | ¹Department of Medicine 3, Cardarelli Hospital, Napoli, Italy; ²School of Specialization in Geriatrics; ³Department of Internal Medicine and Blood Coagulation; ⁴Department of Laboratory Medicine and Transfusion, Federico II University, Napoli, Italy

  Emiliana Marrone

  26-10-2026

  https://doi.org/10.4081/btvb.2026.965

  24

  PDF: 8
• 

  When is percutaneous left atrial appendage closure a valid alternative to oral anticoagulation in atrial fibrillation?

  Vittorio Pengo

  16-10-2026

  https://doi.org/10.4081/btvb.2026.570

  242

  PDF: 30
• 

  Impact of CYP2C19 loss-of-function variants on outcomes in atrial fibrillation patients undergoing percutaneous coronary intervention: rationale and study design of the WOEST-3 genetic substudy

  Simona Chiusolo, Ashley Verburg, Carmela Morizzo, Ron H.N. Van Schaik, Maja Matic, Marieke J.H. Coenen, Michael Maeng, Jurrien ten Berg, Raffaele De Caterina

  28-08-2026

  https://doi.org/10.4081/btvb.2026.421

  1268

  PDF: 128

  APPENDIX: 101

• CO024 | THE ROLE OF BLOOD CLOTTING AND ENDOTHELIAL ACTIVATION IN THE STRATIFICATION OF BLEEDING AND THROMBOTIC RISK OF ATRIAL FIBRILLATION ON ORAL ANTICOAGULANT THERAPY: INSIGHTS FROM THE STRAT-AF 2 STUDY F. Alfano^1|2, AM. Gori^1|2, A. Bertelli¹, G. Ciarrocca Taranta¹, M. Di Gioia², F. Cesari¹, A. Rogolino¹, A. Sorrentino¹, B. Giusti^1|2, R. Marcucci^1|2 | ¹Department of Experimental and Clinical Medicine, University of Florence, Firenze, Italy; ²Center for Atherothrombotic Diseases, Careggi University Hospital, Firenze, Italy

  Francesco Alfano

  26-10-2026

  https://doi.org/10.4081/btvb.2026.726

  35

  PDF: 11

• CO-50 | LEFT ATRIAL APPENDAGE OCCLUSION IN PATIENTS WITH ATRIAL FIBRILLATION AND BLEEDING DISORDERS: A SINGLE-CENTER EXPERIENCE B.M. Roccon¹, M.I. Tassoni¹, G. Quintavalle¹, G. Benatti², F. Gurgoglione², R. Rossi³, C. Cattabiani³, L. Vignali², A. Tagliaferri¹, A. Coppola¹ | ¹SSD Centro Hub Emofilia e Malattie Emorragiche Congenite, Azienda Ospedaliero-Universitaria di Parma, Italy; ²SSD Cardiologia Interventistica, Azienda Ospedaliero-Universitaria di Parma, Italy; ³Laboratorio di Coagulazione, UOC Patologia Clinica, Azienda Ospedaliero-Universitaria di Parma, Italy

  Antonio Coppola

  14-10-2026

  https://doi.org/10.4081/btvb.2026.660

  51

  PDF: 18

• CO069 | POLYSTYRENE NANOPLASTICS PRIME PLATELET TO DRIVE PRO-INFLAMMATORY AND PRO-FIBROTIC ACTIVATION OF CARDIAC FIBROBLASTS Z. Saeed^1|2, M. Dovizio^1|3, C. Milillo^1|3, P. Lanuti^1|4, S. Porro^1|4, F. D’Ascanio^1|4, A. Bruno^1|3, P. Ballerini^1|3, G. Renda^1|2 | ¹Center for Advanced Studies and Technology (CAST), “G. d’Annunzio” University of Chieti-Pescara, Chieti, Italy; ²Department of Neurosciences, Imaging and Clinical Sciences, "G. d'Annunzio" University of Chieti-Pescara, Chieti, Italy; ³Department of Innovative Technologies in Medicine & Dentistry, “G. d’Annunzio” University of Chieti-Pescara, Chieti, Italy; ⁴Department of Medicine and Aging Sciences, “G. d’Annunzio” University of Chieti-Pescara, Chieti, Italy

  Zeeba Saeed

  26-10-2026

  https://doi.org/10.4081/btvb.2026.771

  23

  PDF: 11

• CO020 | LEFT ATRIAL ENLARGEMENT AS A MARKER OF ADVERSE CLINICAL OUTCOMES: PRELIMINARY RESULTS OF A PROSPECTIVE COHORT STUDY B. Clerici¹, M. Perego¹, G. Casazza², A.G. Russo³, L. Massironi⁴, A. Moreo⁵, V. Dadone⁶, S. Birocchi¹, F. Bursi⁴, A. Bonelli⁵, P.V. Mattiello¹, F.M. Casanova¹, C. Pisetta¹, M. Scavone¹, M. Guazzi⁴, C. Giannattasio⁵, S. Pierini⁶, G. Agnelli⁷, G.M. Podda¹ | ¹SC Medicina Generale SP, Ospedale San Paolo, ASST Santi Paolo e Carlo, Università degli Studi di Milano, Italy; ²IRCCS Fondazione Ca’ Granda, Policlinico di Milano, Italy; ³SC Unità di Epidemiologia, ATS della Città Metropolitana di Milano, Italy; ⁴SC Cardiologia, Ospedale San Paolo, ASST Santi Paolo e Carlo, Università degli Studi di Milano, Italy; ⁵SC Cardiologia 4, Ospedale Niguarda, ASST Grande Ospedale Metropolitano Niguarda, Milano, Italy; ⁶SC Cardiologia e Unità di Cura Cardiologica (UCC), Ospedale Bassini, ASST Nord Milano, Italy; ⁷SC di Medicina Interna Vascolare e d’Urgenza – Stroke Unit, Università di Perugia, Italy. B. Clerici and M. Perego contributed as co-first authors

  Bianca Clerici

  26-10-2026

  https://doi.org/10.4081/btvb.2026.722

  25

  PDF: 8

• PO57 | Direct oral anticoagulant determination in urine samples compared to plasma concentrations in outpatients with atrial fibrillation and obesity A. Pannunzio¹, I.M. Palumbo¹, D. Menichelli¹, V. Cammisotto², V. Castellani³, E. Baldacci⁴, R. Mormile⁴, A. Chistolini⁴, G. Bernardini⁵, N. Porcu¹, D. Pastori², J. Harenberg⁶, F. Violi², P. Pignatelli² | ¹Department of General Surgery, Surgical Specialties and Organ Transplantation Paride Stefanini, Sapienza University of Roma, Italy; ²Department of Clinical Internal, Anesthesiological and Cardiovascular Sciences, Sapienza University of Roma, Italy; ³Department of Translational and Precision Medicine, Sapienza University of Roma, Italy; ⁴Department of Hematology, Oncology and Dermatology, Sapienza University of Roma, Italy; ⁵U.O.S.D. Medicina Rigenerativa DAI, Medicina Diagnostica e Radiologia, Policlinico Umberto 1, Roma, Italy; ⁶Ruprecht Karls University of Heidelberg, Germany

  22-10-2025

  https://doi.org/10.4081/btvb.2025.326

  551

  PDF: 16

• CO046 | BLEEDING RISK FACTOR–BASED PHENOTYPES AND THEIR ASSOCIATION WITH MORTALITY AND HEMORRHAGIC OUTCOMES IN ATRIAL FIBRILLATION T. Bucci¹, A.G. Rigutini¹, A. Perrotta¹, A. Moffa¹, C. Seviroli¹, M. Giustozzi², M.C. Vedovati¹, C. Becattini¹ | ¹Internal, Vascular and Emergency Medicine - Stroke Unit, University of Perugia, Perugia, Italy; ²SSD Angiology, San Giovanni Battista Hospital, Foligno, Italy

  Tommaso Bucci

  26-10-2026

  https://doi.org/10.4081/btvb.2026.748

  29

  PDF: 9

• PO140 | HISTORY OF FALLS IN PATIENTS WITH ATRIAL FIBRILLATION: A SYSTEMATIC REVIEW AND META-ANALYSIS A.P. Speziale¹, G. Buoninfante¹, A. Ronca^2|4, B. Corica³, V. Trapani¹, M. Moretti¹, G. Annecchini¹, R. Cangemi¹, V. Raparelli¹, M. Proietti^2|4, S. Basili¹, G.F. Romiti⁵ | ¹Department of Translational and Precision Medicine, Sapienza University of Roma, Roma, Italy; ²Department of Clinical Sciences and Community Health, University of Milano, Milano, Italy; ³University of Modena and Reggio Emilia, Modena, Italy; ⁴Division of Subacute Care, IRCCS Istituti Clinici Scientifici Maugeri, Milano, Italy; ⁵Department of Wellbeing, Health and Environmental Sustainability, Sapienza University of Roma, Rieti, Italy

  Angela Pia Speziale

  26-10-2026

  https://doi.org/10.4081/btvb.2026.956

  25

  PDF: 7

• CO073 | THROMBIN GENERATION PROFILE IN ELDERLY PATIENTS WITH ATRIAL FIBRILLATION: IMPACT OF ORAL ANTICOAGULANT TYPE M. Di Gioia¹, M. Berteotti^1|2, G. Ciarrocca Taranta², F. Alfano^1|2, F. Crudele¹, F. Cesari¹, A.M. Gori^1|2, A. Rogolino¹, B. Giusti^1|2, R. Marcucci^1|2 | ¹Atherothrombotic Diseases, Careggi University Hospital, Firenze, Italy; ²Dep. of Experimental and Clinical Medicine, University of Florence, Italy

  Michela Di Gioia

  26-10-2026

  https://doi.org/10.4081/btvb.2026.775

  26

  PDF: 9
• 

  Perioperative management of patients taking direct oral anticoagulants: challenges in high-bleed-risk surgery and neuraxial anesthesia

  Maria P. Ntalouka, Eleni M. Arnaoutoglou, James D. Douketis

  28-08-2026

  https://doi.org/10.4081/btvb.2026.471

  492

  PDF: 258
• 

  Pleiotropic effects of anti-thrombotic therapies: have direct oral anticoagulants any anti-inflammatory effect?

  Anna Maria Gori, Eleonora Camilleri, Alessia Bertelli, Angela Rogolino, Francesca Cesari, Elena Lotti, Tommaso Capobianco, Walther Iannotti, Betti Giusti , Rossella Marcucci

  14-12-2022

  https://doi.org/10.4081/btvb.2022.50

  1897

  PDF: 647

• PO93 | Use of DOACS in heart transplantation recipients T. Marrazzo¹, A. Delle Femine¹, C. Amarelli², R. Albisinni³ | ¹UOC Medicina Interna e dei Trapianti, Ospedale Monaldi Azienda dei Colli, Napoli; ²UOSD CCH dei Trapianti, Ospedale Monaldi Azienda dei Colli, Napoli; ³UOC CCH Generale, Ospedale Monaldi Azienda dei Colli, Napoli, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.363

  747

  PDF: 17

• CO071 | ATRIAL FIBRILLATION, CEREBRAL SMALL VESSEL DISEASE, AND GENDER MEDICINE: FOCUS ON BIOMARKERS AND NEUROIMAGING F. Alfano^1|2, M. Berteotti^1|2, F. Cesari^1|2, AM. Gori^1|2, E. Salvadori¹, B. Giusti^1|2, A. Bertelli^1|2, L. Bicchi^1|2, F. Fratini³, B. Formelli³, G. Salti³, E. Fainardi^1|4, A. Ginestroni^1|4, S. Chiti⁵, A. Poggesi^1|3, R. Marcucci^1|2 | ¹Department of Experimental and Clinical Medicine, University of Florence, Firenze, Italy; ²Center for Atherothrombotic Diseases, Careggi University Hospital, Firenze, Italy; ³NEUROFARBA Department, Neuroscience Section, University of Florence, Firenze, Italy; ⁴Neuroradiology Unit, Careggi University Hospital, Firenze, Italy; ⁵Health Physics Unit, Careggi University Hospital, Firenze, Italy

  Francesco Alfano

  26-10-2026

  https://doi.org/10.4081/btvb.2026.773

  39

  PDF: 17
• 

  Comment on "Apixaban vs. aspirin for stroke prevention in people with subclinical atrial fibrillation and a history of stroke or transient ischemic attack: subgroup analysis of the ARTESiA randomized controlled trial"

  Vittorio Pengo

  01-07-2025

  https://doi.org/10.4081/btvb.2025.179

  1060

  PDF: 407

• PO31 | Comparative analysis of anticoagulant therapy in patients over 90 years old: vitamin K antagonists versus direct oral anticoagulants G. Sottilotta¹, P. Arrigo², S. Cuzzocrea¹, D. Megalizzi¹, F. Luise³ | ¹UOSD Microcitemie, Emostasi e Trombosi, Grande Ospedale Metropolitano di Reggio Calabria; ²Associazione Italiana Pazienti Anticoagulati, Sezione di Reggio Calabria; ³Laboratorio Analisi. Grande Ospedale Metropolitano di Reggio Calabria, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.292

  598

  PDF: 15

• CO070 | PLASMIN GENERATION AND ITS INTERPLAY WITH COAGULATION AND FIBRINOLYSIS IN ATRIAL FIBRILLATION: IMPACT OF ANTICOAGULANT THERAPY G. Ciarrocca Taranta¹, F. Alfano¹, M. Di Gioia², M. Berteotti^1|2, E. Lotti², F. Cesari², A. Rogolino², F.A. Barbuto¹, A. M Gori^1|2, E. Sticchi^1|2, B. Giusti^1|2, R. Marcucci^1|2 | ¹Dep of Experimental and Clinical Medicine, University of Florence, Italy; ²Atherothrombotic Diseases, Careggi University Hospital, Firenze, Italy

  Giulia Ciarrocca Taranta

  26-10-2026

  https://doi.org/10.4081/btvb.2026.772

  31

  PDF: 7
• 

  Stroke in women: anticoagulation in a complicated puzzle

  Francesco Marongiu, Elvira Grandone, Silvia Marongiu, Antonella Mameli, Doris Barcellona

  26-08-2024

  https://doi.org/10.4081/btvb.2024.137

  1759

  PDF: 462

• PO18 | Does muscle mass matter? Appendicular lean mass as a determinant of anti-XA activity in elderly patientes B.M. Zanforlini¹, V. Bernardi¹, E. Campello², E.M. Bicego¹, C. Curreri¹, A. Vaticano¹, C. Sartori¹, L. Manfron¹, A. Perencin¹, P. Rollo¹, A. Baruffol¹, L. Ruoso¹, C. Simion², C. Bulato², P. Berto², P. Simioni², G. Sergi¹ | ¹Department of Medicine, Geriatrics Section, University of Padova; ²Haemorrhagic and Thrombotic Diseases Unit, Department of Medicine DIMED, Padova University Hospital, Padova, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.278

  600

  PDF: 16

• CO050 | INTERACTION BETWEEN DIRECT ORAL ANTICOAGULANTS AND ANTIEPILEPTIC DRUGS: A MULTICENTER OBSERVATIONAL STUDY A. Lipari¹, S. Sorrentino¹, M. De Siati¹, L. D'Innocenzo¹, A. Ferretti¹, D. Menichelli², V. Cammisotto², P. Pignatelli², G. Ragna³, MC. Vedovati³, C. Becattini³, G. Frisullo⁴, V. Forte⁵, T. Pirozzi¹, L. Di Gennaro¹, M. Basso¹, E. De Candia¹ | ¹Unit of Haemostasis and Thrombosis Diseases, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy; ²Department of Clinical Internal, Anesthesiological and Cardiovascular Sciences, Sapienza University of Roma, Roma, Italy; ³Department of Internal and Cardiovascular Medicine and Stroke Unit, University of Perugia, Perugia, Italy; ⁴Dipartimento di Neuroscienze, Organi di Senso e Torace, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy; ⁵Hematology, Department of Biomedicine and Prevention, University of Rome Tor Vergata, Roma, Italy

  Silvia Sorrentino

  26-10-2026

  https://doi.org/10.4081/btvb.2026.752

  31

  PDF: 13
• 

  Personalized bleeding risk assessment for atrial fibrillation patients on direct oral anticoagulants: the DOAC score

  Paolo Prandoni

  11-10-2023

  https://doi.org/10.4081/btvb.2023.97

  2135

  PDF: 467

• CO23 | Markers of inflammation and hypofibrinolysis are associated with cognitive dysfunction and motor performances in atrial fibrillation patients on oral anticoagulant therapy: insights from the Strat-AF study F. Alfano^1,2, F. Cesari^1,2, A.M. Gori^1,2, M. Berteotti^1,2, E. Salvadori³, B. Giusti^1,2, A. Bertelli^1,2, F. Fratini⁴, A. Rogolino^1,2, B. Formelli^4,5, F. Pescini^4,5, E. Fainardi⁶, E. Barucci⁴, G. Salti⁵, A. Cavaliere⁴, A. Ginestroni⁶, A. Poggesi^4,5, R. Marcucci^1,2 | ¹Department of Experimental and Clinical Medicine, University of Firenze; ²Center for Atherothrombotic Diseases, Careggi University Hospital, Firenze; ³Department of Biomedical and Clinical Sciences, University of Milan; ⁴NEUROFARBA Department, Neuroscience Section, University of Firenze; ⁵Stroke Unit, Careggi University Hospital, Firenze; ⁶Neuroradiology Unit, Careggi University Hospital, Department of Experimental and Clinical Biomedical Sciences, University of Firenze, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.229

  732

  PDF: 26

• CO19 | Hypercoagulability in wild-type transthyretin amyloidosis: evidence from whole blood thromboelastometry A. Napolitano¹, L. Spiezia¹, C. Samà¹, A. Benetti¹, G. Sinigiani², L. De Michieli², A. Cipriani², P. Simioni¹ | ¹First Chair of Internal Medicine, Department of Medicine, University Hospital of Padua; ²Department of Cardiothoracic and Vascular Sciences & Public Health, University Hospital of Padua, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.223

  599

  PDF: 10

• PO130 | HEMORRHAGIC AND THROMBOTIC COMPLICATIONS DURING DOACS TREATMENT: THE IMPORTANCE OF A REGULAR AND PROLONGED FOLLOW-UP D. Barcellona^1|2, A. Mameli², S. Cornacchini², P. Schirru², L. Fenu², V. Casu², F. Marongiu^1|2 | ¹University of Cagliari, Italy; ²Haemostasis and Thrombosis Unit, Azienda Ospedaliero-Universitaria di Cagliari, Italy

  Doris Barcellona

  26-10-2026

  https://doi.org/10.4081/btvb.2026.946

  32

  PDF: 6

• PO081 | FROM VON WILLEBRAND DISEASE TO MILD HEMOPHILIA A AND BACK: THREE ILLUSTRATIVE CASES HIGHLIGHTING THE ROLE OF GENETIC TESTING IN IMPROVING DIAGNOSTIC ACCURACY E. Zacchi^1|2, L. Piscitelli¹, A. Vaisfeld^2|3, C. Manzi¹, L. Godino², P. Magini², F. Riccardi⁴, L. Valdrè¹ | ¹Inherited Bleeding Disorders Unit, IRCCS AOUBO, Bologna, Italy; ²Medical Genetics Unit, IRCCS AOUBO, Bologna, Italy; ³Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy; ⁴Regional Reference Centre for Inherited Bleeding Disorders, University Hospital of Parma, Parma, Italy

  Eliana Zacchi

  26-10-2026

  https://doi.org/10.4081/btvb.2026.897

  24

  PDF: 7

• PO055 | THROMBIN GENERATION PROFILES IN PATIENTS WITH WILD-TYPE TRANSTHYRETIN AMYLOIDOSIS L. Spiezia¹, A. Napolitano¹, C. Bulato¹, S. Toffanin¹, A. Benetti¹, C. Samà¹, L. De Michieli², G. Sinigiani², A. Cipriani², P. Simioni¹ | ¹Dipartimento di Medicina, Azienda Osp. Università di Padova, Italy; ²Dipartimento di Scienze cardio toraco vascolari, Azienda Osp. Università di Padova, Italy

  Luca Spiezia

  26-10-2026

  https://doi.org/10.4081/btvb.2026.871

  22

  PDF: 7

• PO106 | INTERACTIONS BETWEEN DIRECT ORAL ANTICOAGULANTS AND ANTIEPILEPTIC DRUGS (INTER-DOAC): A PROSPECTIVE OBSERVATIONAL STUDY A. Rafanelli¹, C. Pizzanelli³, M. Biagini¹, P. Chiarugi⁴, M. Casini⁴, P. Capozza⁵, G. Guarini⁵, L. Malloggi⁴, G. Siciliano³, R. De Caterina^5|6, L. Carrozzi^1|2, F. Pistelli^1|2, L. Marconi², A. Celi^1|2, R. Pancani² | ¹Pulmonary Division, Dep. of Surgical, Medical and Molecular Pathology and Critical Care Medicine, University of Pisa, Pisa, Italy; ²Pulmonary Unit, Cardiothoracic and Vascular Dep., University Hospital of Pisa, Pisa, Italy; ³Neurology Unit, Dep. of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy; ⁴Clinical Chemistry Laboratory, Dep. of Laboratory Medicine, University Hospital of Pisa, Pisa, Italy; ⁵Cardiology Unit, Cardiothoracic and Vascular Dep., University Hospital of Pisa, Pisa, Italy; ⁶Cardiology Division, Dep. of Surgical, Medical and Molecular Pathology and Critical Care Medicine, University of Pisa, Pisa, Italy

  Annalisa Rafanelli

  26-10-2026

  https://doi.org/10.4081/btvb.2026.922

  24

  PDF: 9

• PO099 | CORRELATION BETWEEN DIRECT ORAL ANTICOAGULANTS PLASMA LEVELS AND BRAIN VASCULAR EVENTS L. Riva¹, M. Paolucci², S. Forlivesi², M. Gentile², G. Casella¹, A. Zini², R. Marcucci³ | ¹UOC Cardiologia Ospedale Maggiore AUSL Bologna, Italy; ²IRCCS Istituto delle Scienze Neurologiche di Bologna UOC Neurologia e Rete Stroke metropolitana Ospedale Maggiore AUSL Bologna, Italy; ³SOD Malattie Aterotrombotiche AOU Careggi Università degli Studi di Firenze, Italy

  Letizia Riva

  26-10-2026

  https://doi.org/10.4081/btvb.2026.915

  23

  PDF: 9

• PO50 | Treatment with BTK inhibitors in patients affected by chronic lymphocytic leukemia: safety and hemostasis L. Gurgoglione, C.A. Piro, I. Scortechini, I. Battilà, M.C. Merlo, A. R. Scortechini, S. Rupoli, A. Poloni | Hematology Unit, AOU delle Marche-Università Politecnica delle Marche, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.319

  525

  PDF: 15

• CO042 | BLEEDING RISK IN PATIENTS RECEIVING CONCURRENT TREATMENT WITH DIRECT ORAL ANTICOAGULANTS AND CORTICOSTEROIDS: A SYSTEMATIC REVIEW M.A. Capparella¹, R. Talerico², C. Cavallaro², M. Iorio², F. Bossi¹, A. Porfidia², K. Abe³, M. Biglietto⁴, A. Chistolini⁴, A. Holt⁵, L. Lahousse^6|7, R. Pola², C. Becattini¹, M.C. Vedovati¹ | ¹Internal, Vascular and Emergency Medicine – Stroke Unit, University of Perugia, Italy; ²Thrombosis Unit, Department of Geriatric, Orthopedic, and Rheumatologic Sciences, Fondazione Policlinico A. Gemelli IRCCS, Roma, Italy; ³Division of Gastroenterology, Department of Medicine, Teikyo University School of Medicine, Tokyo, Japan; ⁴Hematology, Department of Translational and Precision Medicine, Sapienza University of Roma, Italy; ⁵Department of Cardiology, Copenhagen University Hospital – Herlev and Gentofte, Copenhagen, Denmark; ⁶Department of Bioanalysis, Pharmaceutical Care Unit, Faculty of Pharmaceutical Sciences, Ghent University, Ghent, Belgium; ⁷Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands

  Maria Alessandra Capparella

  26-10-2026

  https://doi.org/10.4081/btvb.2026.744

  26

  PDF: 10
• 

  The new era of anticoagulation: factor XI and XII inhibitors

  Domenico Prisco, Irene Mattioli, Raffaele De Caterina, Alessandra Bettiol

  07-06-2023

  https://doi.org/10.4081/btvb.2023.76

  3169

  PDF: 1330

• CO08 | The utility of urine qualitative assessment for direct oral anticoagulants in routine clinical practice F. Schieppati^1,2, P. Gomez-Rosas^1,3, C. Ambaglio¹, V. Brusegan¹, Oc. Cretu^1,2, E. Galimberti¹, F. Zunino¹, L. Barcella¹, J. Harenberg^4,5, A. Falanga^1,2, M. Marchetti^1,2 | ¹Immunohematology and Transfusion Medicine, Hospital Papa Giovanni XXIII, Bergamo, Italy; ²School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy; ³Maastricht University Medical Center, Cardiovascular Research Institute Maastricht, Maastricht, The Netherlands; ⁴Ruprecht Karls University of Heidelberg, Germany; ⁵Germany DOASENSE GmbH, Heidelberg, Germany

  22-10-2025

  https://doi.org/10.4081/btvb.2025.212

  749

  PDF: 21

• PO098 | REAL-WORLD EMERGENCY DEPARTMENT USE OF ANDEXANET ALFA FOR FACTOR XA INHIBITOR REVERSAL: AN ITALIAN COHORT M.P. Donadini^1|2, R. Brivio¹, S. Bozzato², L.M. Caiano², L. Galli², L. Bertù¹, F. Cortellaro², W. Ageno³ | ¹University of Insubria, Varese, Italy; ²ASST Sette Laghi, Varese, Italy; ³University of Padua, Padova, Italy

  Marco Paolo Donadini

  26-10-2026

  https://doi.org/10.4081/btvb.2026.914

  35

  PDF: 10

• PO13 | Monitoring of anti-factor XA activity levels in patients treated with direct oral anticoagulants and concomitant tyrosine kinase inhibitors agents: a monocentric experience E. Santacroce^1,2, C. Santoro¹, E. Baldacci¹, S. Ligia¹, R. Mormile¹, M. Biglietto¹, M. Totaro¹, F. R. Mauro¹, M. Breccia¹, A. Chistolini¹ | ¹Department of Translational and Precision Medicine, Haematology, Sapienza University of Roma; ²Department of Clinical and Molecular Medicine, Sapienza University of Roma, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.313

  649

  PDF: 20

• CO039 | CLINICAL SAFETY AND MONITORING OF APIXABAN IN HEMODIALYSIS PATIENTS: A PROSPECTIVE STUDY S. Guglielmo¹, M. Lovisotto¹, E. De Bon², E. Pierobon³, S. Barbar² | ¹Internal Medicine, Department of Medicine; ²Thrombosis and Haemostasis Unit, Department of Medicine; ³Nephrology and Dialysis Unit, Azienda Ulss 6 Euganea, Cittadella and Camposampiero, Padova, Italy

  Simone Guglielmo

  26-10-2026

  https://doi.org/10.4081/btvb.2026.741

  28

  PDF: 11

• PO124 | BLEEDING COMPLICATIONS DURING ANTICOAGULATION WITH DOACS FOR NVAF AND THEIR MOST COMMON RISK FACTORS A. delle Femine, P. Di Micco, P. Sommese, M. Di Napoli, A. Di Salvatore, M. Galdiero, A. Lobasso, R. Serpico, V. Brunelli, A. Di Fusco, C. di Gennaro | U.O.C. Medicina Interna, Osp. Santa Maria delle Grazie, Pozzuoli, Italy

  Augusto Delle Femine

  26-10-2026

  https://doi.org/10.4081/btvb.2026.940

  20

  PDF: 6

• PO095 | HEPARIN-INDUCED THROMBOCYTOPENIA PRESENTING AS A CIRCUIT-TRIGGERED PULMONARY SYNDROME IN HEMODIALYSIS: A CASE REPORT S.P. Colapietra, M. Gino | Osp. Molinette, Torino, Italy

  Selene Pia Colapietra

  26-10-2026

  https://doi.org/10.4081/btvb.2026.911

  25

  PDF: 8
• 

  Major bleedings in mechanical prosthetic heart valves patients on Vitamin K antagonist treatment. Data from the PLECTRUM Study

  Daniela Poli, Emilia Antonucci, Gualtiero Palareti, Roberto Facchinetti, Pietro Falco, Giuseppina Serricchio, Teresa Lerede, Lucilla Masciocco, Paolo Gresele, Sophie Testa

  27-07-2022

  https://doi.org/10.4081/btvb.2022.34

  5618

  PDF: 631

  Supplementary Files: 267

• PO118 | VARIATION OF EGFR IN PATIENT IN DOACS THERAPY S. Vivolo, C. Gagliardi, A. Ciampa | U.O.S.D. Centro Emostasi Aorn S. G. Moscati Avellino, Italy

  Sabrina Vivolo

  26-10-2026

  https://doi.org/10.4081/btvb.2026.934

  19

  PDF: 10

• PO154 | CORONARY REVASCULARIZATION IN ACUTE CORONARY SYNDROME IN PATIENT WITH MILD HEMOPHILIA B: A CASE REPORT D. Fumarulo, R. Corrado, M. Canfora, M. Mazzetti, M. Littera, D. Prisco, C. Tamburini | Internal Medicine, Careggi Hospital, University of Florence, Firenze, Italy

  Daniela Fumarulo

  26-10-2026

  https://doi.org/10.4081/btvb.2026.970

  21

  PDF: 7
• 

  PO27 | URINE QUALITATIVE ASSESSMENT OF DIRECT ORAL ANTICOAGULANTS IN ROUTINE CLINICAL PRACTICE F. Schieppati^1|2, P. Gomez-Rosas^1|3, C. Ambaglio¹, V. Brusegan¹, O.C. Cretu¹, E. Galimberti¹, F. Zunino¹, L. Barcella¹, J. Harenberg^4|5, A. Falanga^1|2, M. Marchetti^1|2 | ¹Immunohematology and Transfusion Medicine, Hospital Papa Giovanni XXIII, Bergamo, Italy; ²School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy; ³Maastricht University Medical Center, Cardiovascular Research Institute Maastricht, Maastricht, The Netherlands; ⁴Ruprecht Karls University of Heidelberg, Heidelberg, Germany; ⁵DOASENSE GmbH, Heidelberg, Germany

  ICTHIC 2026

  16-04-2026

  https://doi.org/10.4081/btvb.2026.522

  454

  PDF: 96

• PO20 | Impact of endovascular treatment on functional outcome in ischemic stroke: a real-world retrospective study M.G. Mosconi¹, G. Maraziti¹, M. Paciaroni², J. Fagotti³, V. Caso¹ | ¹Azienda Ospedaliera di Perugia; ²Università degli Studi di Ferrara; ³Ospedale San Giovanni Battista, Foligno (PG), Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.280

  662

  PDF: 18

• PO114 | A CASE OF ACQUIRED HEMOPHILIA AFTER TAVI AND CORONARY ANGIOPLASTY IN PATIENT WITH ATRIAL FIBRILLATION AND MULTIPLES CARDIOVASCULAR RISK FACTORS – THE ART AND SCIENCE OF THERAPEUTIC CONFLICT M.M. Poggi¹, C. Tamburini², M. Littera², M. Mazzetti² | ¹SOC Medicina 1, Nuovo Ospedale Prato, Prato, Italy; ²SOD Medicina Interna Interdisciplinare, Azienda Ospedaliera Universitaria Careggi, Firenze, Italy

  Matteo Maria Poggi

  26-10-2026

  https://doi.org/10.4081/btvb.2026.930

  26

  PDF: 7

• PO80 | Heparin-induced thrombocytopenia: a monocentric experience with danaparoid L. D’Innocenzo, S. Sorrentino, M. De Siati, A. Ferretti, E. De Candia | Unit of Haemostasis and Thrombosis Diseases, Fondazione Policlinico Universitario A. Gemelli, IRCCS, Roma, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.349

  702

  PDF: 13

• CO012 | LONG-TERM RISK OF RECURRENT VENOUS THROMBOEMBOLISM IN ADULT PATIENTS WITH ACTIVE CANCER AND FIRST CATHETER-RELATED UPPER EXTREMITY DEEP VEIN THROMBOSIS AFTER DISCONTINUATION OF ANTICOAGULANT TREATMENTS AND LINE REMOVAL: A RETROSPECTIVE MULTI-CENTER COHORT STUDY – CANCER-CRT STUDY L. Girardi^1|2, W. Ageno³, L. Bertù¹, C. Lodigiani⁴, L.A. Ciuffini⁴, M.C. Vedovati⁵, C. Becattini⁵, A. Sammarco⁶, G. Camporese⁶, G. Cuni^1|7, C. Ambaglio⁷, M.P. Donadini¹ | ¹Research Center on Thromboembolic Diseases and Antithrombotic Treatment, Department of Medicine and Surgery, University of Insubria, Varese, Italy; ²Department of Medicine, The Ottawa Hospital Research Institute, University of Ottawa, Ontario, Canada; ³Department of Medicine, University of Padua, Padova, Italy; ⁴Center for Thrombosis and Hemorrhagic Diseases, IRCCS Humanitas Research Hospital, Rozzano, Milano, Italy; ⁵Internal and Cardiovascular Medicine-Stroke Unit, University of Perugia, Perugia, Italy; ⁶Clinica Medica 1, Department of Medicine, DIMED, Padova University Hospital, Padova, Italy; ⁷Immunohematology and Transfusion Medicine, Department of Transfusion Medicine and Hematology, ASST Papa Giovanni XXIII, Bergamo, Italy

  Laura Girardi

  26-10-2026

  https://doi.org/10.4081/btvb.2026.714

  35

  PDF: 9

• PO108 | DIRECT ORAL ANTICOAGULANTS IN PATIENTS WITH VENOUS THROMBOEMBOLISM RECEIVING LONG-TERM IMMUNOSUPPRESSIVE THERAPY AFTER LIVER AND KIDNEY TRANSPLANTATION: A SINGLE-CENTER EXPERIENCE U. Mazzarelli¹, L. Agrelli¹, A. Cirillo¹, C. Crescenzo², M. Triggiani¹, A. Guida³ | ¹Dipartimento di Medicina Interna, Università degli studi di Salerno, Italy; ²UOC Nefrologia e Trapianti di rene; ³Centro per le malattie emorragiche congenite e malattie trombotiche, AOU San Giovanni di Dio e Ruggi d'Aragona Salerno, Italy

  Anna Guida

  26-10-2026

  https://doi.org/10.4081/btvb.2026.924

  29

  PDF: 9

• PO70 | Clinical safety and monitoring of apixaban combined with tacrolimus and everolimus in kidney transplant patients: a prospective study S. Guglielmo¹, E. De Bon², L. Scarano¹, R. Fabris¹, E. Pierobon³, S. Barbar² | ¹Internal Medicine, Department of Medicine, Azienda ULSS 6 Euganea, Cittadella; ²Thrombotic and Hemorrhagic Disorders Unit, Department of Medicine, Azienda ULSS 6 Euganea, Cittadella; ³Nephrology and Dialysis Unit, Azienda ULSS 6 Euganea, Cittadella and Camposampiero, Padova, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.339

  640

  PDF: 25
• 

  Preface to the 13^th International Conference on Thrombosis and Hemostasis Issues in Cancer, 2026

  Anna Falanga, Benjamin Brenner, Alok A. Khorana

  16-04-2026

  https://doi.org/10.4081/btvb.2026.479

  928

  PDF: 232

• PO022 | ARTIFICIAL INTELLIGENCE–ASSISTED PREDICTION OF THROMBOTIC AND HEMORRHAGIC COMPLICATIONS IN PATIENTS TREATED WITH VITAMIN K ANTAGONISTS: A RETROSPECTIVE EXPLORATORY STUDY G. Sottilotta¹, F. Misiti², G. Praticò¹, D. Megalizzi¹, F. Luise³ | ¹UOSD Microcitemie - Emostasi e Trombosi; ³Laboratorio Analisi Grande Ospedale Metropolitano di Reggio Calabria, Italy; ²Associazione Emofilici di Reggio Calabria, Italy

  Gianluca Sottilotta

  26-10-2026

  https://doi.org/10.4081/btvb.2026.838

  31

  PDF: 12

• CO-78 | REAL-WORLD MANAGEMENT OF ACQUIRED HEMOPHILIA A: FOCUS ON RECOMBINANT PORCINE FVIII AS FIRST-LINE HEMOSTATIC TREATMENT AND LONG-TERM OUTCOMES M. Leotta, A. Strangio, A. Ierardi, R.C. Santoro | Hemophilia, Hemostasis and Thrombosis Centre, Azienda Ospedaliero Universitaria Renato Dulbecco, Catanzaro, Italy

  Marzia Leotta

  14-10-2026

  https://doi.org/10.4081/btvb.2026.688

  44

  PDF: 16