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  Bioequivalence of von Willebrand factor-containing concentrates: implications for the choice in patients with von Willebrand disease. A position paper from the Italian Association of Hemophilia Centers

  Ezio Zanon, Giancarlo Castaman, Augusto Bramante Federici, Maria Elisa Mancuso, Gianfranco Pasut, Alberto Tosetto, Angiola Rocino, Rita Carlotta Santoro

  26-01-2026

  https://doi.org/10.4081/btvb.2026.415

  1006

  PDF: 268

  HTML: 77
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  The landscape of rare coagulation factor deficiency management in Italy: a national hemophilia center survey

  Silvia Linari, Renato Marino, Marzia Leotta, Antonio Coppola, Patrizia Di Gregorio, Augusto Bramante Federici, Flora Peyvandi, Cristina Santoro, Ezio Zanon, Rita Carlotta Santoro

  05-11-2025

  https://doi.org/10.4081/btvb.2025.369

  1109

  PDF: 154

  HTML: 46

  Appendix: 83
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  The key to fibrinolysis and thrombolysis

  Roger Lijnen, Désiré Collen

  09-09-2025

  https://doi.org/10.4081/btvb.2025.368

  1534

  PDF: 296

  HTML: 143

• PO42 | Acquired Von Willebrad syndrome in patients with myeloproliferative syndrome: literature review and single-center experience A. Strangio, M. Leotta, A. Ierardi, R C. Santoro | UO Emofilia, Emostasi e Trombosi, AOU R Dulbecco, Catanzaro, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.305

  450

  PDF: 0
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  PO03 | HEPATIC FIBROSIS–DRIVEN TISSUE FACTOR EXPRESSION BY MALIGNANT CHOLANGIOCYTES IS ASSOCIATED WITH CANCER-ASSOCIATED THROMBOSIS AND POOR SURVIVAL IN INTRAHEPATIC CHOLANGIOCARCINOMA L. Fabris^1|2|3, Y. Frión-Herrera¹, C. Venturin^1|3, M. Cadamuro⁴, J. Gasparello⁵, C. M. Radu^1|2, M. Fassan^1|5, C. Mescoli⁶, U. Cillo^7|8, E. Gringeri^7|8, G. Zanus^7|9, E. Campello^1|2, M. Strazzabosco³, P. Simioni^1|2 | ¹Department of Medicine, University of Padua; ²Clinical Medicine 1 and Thrombotic and Haemorrhagic Disease Unit, and Haemophilia Center, Padua University-Hospital; ³Department of Internal Medicine, Digestive Disease Section, Liver Center, Yale University, New Haven, CT, USA; ⁴School of Medicine and Surgery, University of Milan-Bicocca, Milan, Italy; ⁵Pathology Unit, Ca' Foncello Hospital, ULSS2 Marca Trevigiana, Treviso; ⁶Pathology Unit, Padua University-Hospital; ⁷Department of Surgery, Oncology and Gastroenterology, University of Padua; ⁸Hepatobiliary Surgery and Liver Transplantation Unit, Padua University-Hospital; ⁹General Surgery Unit, Ca' Foncello Hospital, ULSS2 Marca Trevigiana, Treviso, Italy

  Società Italiana di Emostasi e Trombosi

  16-04-2026

  https://doi.org/10.4081/btvb.2026.499

  160

  PDF: 40

• CO02 | Hepatic fibrosis as predictor of cancer-associated thrombosis in patients with intrahepatic cholangiocarcinoma Y. Frion-Herrera^1,2, C. Venturin^1,3, M. Cadamuro⁴, J. Gasparello⁵, C.M. Radu¹, M. Fassan⁵, C. Mescoli⁶, U. Cillo⁷, E. Gringeri⁷, G. Zanus⁸, L. Fabris^1,3, P. Simioni¹ | ¹Clinical Medicine and Thrombotic and Haemorrhagic Disease Unit, and Haemophilia Center, Padua University-Hospital, Department of Medicine [DIMED], University of Padua, Italy; ²Department of Biology [DiBio], University of Padua, Italy; ³Department of Internal Medicine, Digestive Disease Section, Liver Center, Yale University, New Haven, CT, USA; ⁴School of Medicine and Surgery, University of Milan-Bicocca, Milan, Italy; ⁵Department of Pathology Ca’ Foncello Hospital, ULSS2 Marca Trevigiana, Italy; ⁶Pathology Unit, Padua University-Hospital, Padua, Italy; ⁷Hepatobiliary Surgery and Liver Transplantation Unit, Padua University-Hospital, Department of Surgery, Oncology and Gastroenterology [DISCOG], University of Padua, Italy; ⁸General Surgery Unit, Ca’ Foncello Hospital, ULSS2 Marca Trevigiana, Department of Surgery, Oncology and Gastroenterology [DISCOG], University of Padua, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.207

  591

  PDF: 0

• PO77 | The clinical awareness of mixing test interpretation in the era of complex reporting algorithm: do we forget the origins? A. Fassina, L. De Valentin, S. Luzi, R. Turrini, A. Antico, L. Zardo | Laboratorio Analisi Castelfranco Veneto, ULSS Marca Trevigiana, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.346

  525

  PDF: 0
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  Diagnostic challenges in current laboratory practice at Italian Hemophilia Centers: findings from a nationwide survey

  Tiziano Martini, Alessandra Valpreda, Marina Marchetti, Alberto Catalano, Laura Contino, Raimondo De Cristofaro, Augusto Bramante Federici, Ilaria Quaglia, Rossana Rossi, Rita Carlotta Santoro, Armando Tripodi, Angelo Claudio Molinari

  12-03-2026

  https://doi.org/10.4081/btvb.2026.431

  195

  PDF: 52

  Supplementary: 13

• PO39 | Bleeding events in Von Willebrand disease type 1 yearly treatable with desmopressin A. Gringeri^1,2, P.M. Mannucci³, M. Gringeri⁴, G. Castaman⁵, F. Peyvandi^3,6 | ¹Fondazione Charta, Milan; ²Centro di Sanità Solidale, Lucca; ³Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center and Fondazione Luigi Villa, Milan; ⁴Department of Medical Biotechnologies and Translational Medicine, Postgraduate School of Clinical Pharmacology and Toxicology, University of Milan; ⁵Centre for Bleeding Disorders and Coagulation, Careggi University Hospital, Firenze; ⁶Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.302

  523

  PDF: 0
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  Diagnostic and management practices for inherited fibrinogen disorders: a nationwide survey of Italian Hemophilia Treatment Centers

  Renato Marino, Silvia Linari, Marzia Leotta, Antonio Coppola, Chiara Biasoli, Maria Elisa Mancuso, Flora Peyvandi, Cristina Santoro, Ezio Zanon, Rita Carlotta Santoro

  02-12-2025

  https://doi.org/10.4081/btvb.2025.372

  475

  PDF: 74

  HTML: 57

  Supplementary: 32

  Appendix: 49
• 

  OC13 | VON WILLEBRAND FACTOR PREDICTS POOR OUTCOME IN PANCREATIC CANCER AND MEDIATES TUMOR-ENDOTHELIUM INTERACTIONS FACILITATING METASTASIS B. Ünlü¹, Z. Zhao¹, N. Joshi¹, S. De¹, A. Chion¹, I. Schoen¹, J. O’Donnell¹, M. Flick², M. Fishel^3|4, J. O’Sullivan¹ | ¹School of Pharmacy and Biomolecular Sciences, Irish Centre for Vascular Biology, Royal College of Surgeons in Ireland, Dublin, Ireland; ²UNC Blood Research Center, University of North Carolina at Chapel Hill, Chapel Hill, USA; ³IU Simon Comprehensive Cancer Center, Indiana University School of Medicine, Indianapolis, IN, USA; ⁴Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN, USA

  Società Italiana di Emostasi e Trombosi

  16-04-2026

  https://doi.org/10.4081/btvb.2026.496

  166

  PDF: 39
• 

  PO20 | DYSFUNCTION OF THE ADAMTS-13/VON WILLEBRAND FACTOR AXIS, MEDIATED BY NETOSIS, AS A DRIVER OF PROTHROMBOTIC STATE AND UNFAVORABLE PROGNOSIS IN ONCOGYNECOLOGICAL PATIENTS V. Bitsadze¹, E. Beloborodova², J. Khizroeva¹, A. Solopova¹, M. Tretyakova¹, N. Gashimova¹, K. Grigoreva¹, A. Tatarintseva¹, J. Christophe Gris^1|3, I. Elalamy^1|4|5, G. Gerotziafas^1|4|5, A. Makatsariya¹ | ¹Department of Obstetrics, Gynecology and Perinatal Medicine, N. F. Filatov Clinical Institute of Children’s Health, I. M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia; ²Clinic MEDSI Network of Medical Centers in Moscow, Russia; ³Faculty of Pharmaceutical and Biological Sciences, Montpellier University, France; ⁴Department Hematology and Thrombosis Center, Medicine Sorbonne University, Paris, France; ⁵Hospital Tenon, Paris, France

  Società Italiana di Emostasi e Trombosi

  16-04-2026

  https://doi.org/10.4081/btvb.2026.515

  171

  PDF: 50

• PO27 | B-cell lymphoproliferative disorder and acquired coagulopathy: an insidious link C. Caputo, P. Conca, I.L. Calcaterra, E. Cimino, M. Romeo, M. Aversano, E. Franco, C. De Luca, R. Russo, C. Fierarossa, M.N.D. Di Minno, A. Tufano | Department of Clinical Medicine and Surgery, Federico II University, Naples, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.288

  504

  PDF: 0

• PO41 | Comparison of the haemorrhagic phenotype between female and male patients affected by autosomal inherited bleeding disorders in a single-centre cohort B. Borsellino^1,3, C. Zuccotti², L. Guarnera^3,4, C. Biasoli⁵, P. Pedrazzi⁵, T. Martini¹ | ¹Haemophilia Centre, Immune-Haematology and Transfusion Medicine, University Hospital “Città della Salute e della Scienza”, Turin, Italy; ²Department of Clinical Pathology, Bufalini Hospital, Cesena, Italy; ³Department of Biomedicine and Prevention, PhD in Immunology, Molecular Medicine and Applied Biotechnology, University of Roma Tor Vergata, Roma, Italy; ⁴Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH, USA; ⁵Haemophilia and Transfusion Centre, Bufalini Hospital, Cesena, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.304

  515

  PDF: 0

• PO23 | Plasmic score applicability for the diagnosis of thrombotic microangiopathy associated with acquired ADAMTS13 deficiency in emergency settings at the hub laboratory of AUSL Romagna: state of the art and future prospects M. Olivieri¹, M. Rosetti¹, A. Clementoni¹, V. Marinucci¹, M. Monterosso¹, E. Massari¹, V. Polli¹, M. Zauli¹, V. Sambri² | ¹Clinical Pathology Unit; ²Unit of Microbiology, Area Hub Laboratory, Cesena, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.284

  534

  PDF: 0

• PO12 | Characterisation and real word clinical data of HEM006, a newly formulated intranasal spray desmopressin (DDAVP) to address a global treatment gap G. De Giorgi¹, A. Gringeri², R. Franceschini¹, A. Koganti³ | ¹Hemorare Srl, Italy; ²Fondazione Charta, Milan, Italy; ³Quenya LLC, USA

  22-10-2025

  https://doi.org/10.4081/btvb.2025.274

  454

  PDF: 0

• PO10 | Clinical and laboratory features of long-Covid syndrome: a cross-sectional study of 1,337 Covid-19 survivors C. Ambaglio¹, S. V. Benatti², C. J. Tartari^1,3, L. Russo^1,3, S. Bolognini^1,3, C. Ticozzi¹, F. Schieppati¹, V. Brusegan¹, S. Venturelli², L. Barcella¹, M. Rizzi², M. Marchetti^1,3, A. Falanga^1,3 | ¹Department of Immunohematology and Transfusion Medicine, Papa Giovanni XXIII Hospital, Bergamo; ²Division of Infectious Diseases, Papa Giovanni XXIII Hospital, Bergamo; ³Department of Medicine and Surgery, University of Milan Bicocca, Monza, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.272

  521

  PDF: 0

• CO21 | Viscoelastic testing in inherited bleeding disorders: a cross-sectional comparison between viscoelastic coagulation monitoring and rotational thromboelastometry C. Simion, C. Samà, C. Bulato, G. Gottardi, D. Regazzo, E. Campello, P. Simioni | Department of Medicine – DIMED, University of Padua, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.227

  518

  PDF: 0