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Bleeding, Thrombosis and Vascular Biology

Editor-in-Chief: Giovanni de Gaetano, Italy | eISSN: 2785-5309

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  • The key to fibrinolysis and thrombolysis

    Roger Lijnen, Désiré Collen
    09-09-2025
    https://doi.org/10.4081/btvb.2025.368
    1712
    PDF: 531
    HTML: 265
  • The history of the TIMI, GISSI, and ISIS trials: the development of thrombolytic therapy in acute myocardial infarction

    Aldo Pietro Maggioni, Claudio Fresco, Luigi Tavazzi
    13-10-2026
    https://doi.org/10.4081/btvb.2026.577
    421
    PDF: 65
  • Executive summary of the SISET position paper on the management of antithrombotic therapy in left ventricular thrombus

    Emanuele Valeriani, Arianna Pannunzio, Danilo Menichelli, Domenico Prisco, Walter Ageno, Daniele Pastori, Pasquale Pignatelli
    16-12-2025
    https://doi.org/10.4081/btvb.2025.401
    488
    PDF: 144
    HTML: 116
  • CO021 | TIME COURSE OF LP(a) LEVELS AFTER ACUTE CORONARY SYNDROME: A LONGITUDINAL STUDY G. Barbieri1, A.M. Gori1, G. Ciarrocca Taranta1, M. Di Gioia1, F. Alfano1, E. Lotti1, A. Rogolino1, F. Cesari1, B. Giusti1, M. Berteotti1, R. Marcucci1 | 1Atherothrombotic Diseases Center, Department of Experimental and Clinical Medicine, University of Florence - Careggi Hospital, Firenze, Italy

    Giulia Barbieri
    26-10-2026
    https://doi.org/10.4081/btvb.2026.723
    60
    PDF: 24
  • CO076 | ASSOCIATION OF MATRIX METALLOPROTEINASE 2 PLASMA LEVELS WITH CARDIOVASCULAR EVENTS IN PATIENTS WITH ATRIAL FIBRILLATION: A NESTED CASE CONTROL STUDY FROM THE ATHERO-AF COHORT D. Menichelli1, E. Falcinelli2, P. Pignatelli3, R. Carnevale4|5, A. D’Amico4, F. Violi2, P. Gresele2, D. Pastori4|5, F. Paciullo6 | 1Dip. di Chirurgia Generale e Specialità Chirurgiche Paride Stefanini, Università La Sapienza, Roma, Italy; 2Dip. di Medicina e Chirurgia, Sez. di Medicina Interna Cardiovascolare, Università degli Studi di Perugia, Italy; 3Dip. di Scienze Medico-Chirurgiche e Biotecnologie, Università La Sapienza, Latina, Italy; 4IRCCS Neuromed, Pozzilli, Isernia, Italy; 5Dip. di Scienze Mediche e Cardiovascolari, Università La Sapienza, Roma, Italy; 6Fac. di Medicina e Chirurgia , Vita-Salute San Raffaele University, Milano, Italy

    Francesco Paciullo
    26-10-2026
    https://doi.org/10.4081/btvb.2026.778
    55
    PDF: 26
  • Platelets versus monocytes as cellular sources of blood-borne tissue factor: a quantitative and functional comparison in healthy subjects and in patients with STEMI

    Marina Camera, Marta Brambilla, Alessia Becchetti, Patrizia Della Valle, Nicola Cosentino, Jeness Campodonico, Gian Carlo Marenzi, Daniela Trabattoni, Peter L.A. Giesen, Vincenzo Toschi, Elena Tremoli
    12-10-2026
    https://doi.org/10.4081/btvb.2026.584
    476
    PDF: 57
    SUPPLEMENTARY FILES: 30
  • Platelet transcriptomic changes in myocardial infarction are sex and clinical subtype-related: a step forward towards precision medicine?

    Loredana Bury, Alessio Branchini, Francesco Bernardi, Paolo Gresele
    11-03-2025
    https://doi.org/10.4081/btvb.2025.173
    906
    PDF: 284
  • PO68 | Whole blood hypercoagulable profiles in a patient with markedly elevated lipoprotein(A) plasma levels and thrombotic complications: a case report C. Portinari, M. Biolo, A. Napolitano, L. Spiezia, A. Colpo, S. Zambon, A. Zambon, P. Simioni | Department of Medicine, Padova University Hospital, Padova, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.337
    657
    PDF: 31
  • OC10 | FROM DESIGN TO CLINICAL PHASE 3 IN ONCOLOGY: CD13-TARGETED TISSUE FACTOR AND TUMOR INFARCTION W.E. Berdel, C. Schwöppe, C. Brand, K. Hessling, A.F. Berdel, T. Kessler, G. Lenz, R.M. Mesters, C. Schliemann | Department of Medicine A, University Hospital, Muenster, Germany

    ICTHIC 2026
    16-04-2026
    https://doi.org/10.4081/btvb.2026.493
    500
    PDF: 105
  • PO154 | CORONARY REVASCULARIZATION IN ACUTE CORONARY SYNDROME IN PATIENT WITH MILD HEMOPHILIA B: A CASE REPORT D. Fumarulo, R. Corrado, M. Canfora, M. Mazzetti, M. Littera, D. Prisco, C. Tamburini | Internal Medicine, Careggi Hospital, University of Florence, Firenze, Italy

    Daniela Fumarulo
    26-10-2026
    https://doi.org/10.4081/btvb.2026.970
    47
    PDF: 23
  • PO46 | Intravitreal treatment with faricimab in patients with age-related macular degeneration M. Alfonsetti1, R. Liani1, P.G.M. Simeone1, M. Frezza1, A. Ricci3, S. Lattanzio1, R. D’Aloisio2, L. Toto2, F. Santilli1 | 1Department of Medicine and Aging, Center for Advanced Studies and Technology “CAST”; 2Ophthalmology Clinic, Department of Medicine and Aging; 3Department of Pharmacy, University “G. d’Annunzio” of Chieti Pescara, Chieti, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.315
    497
    PDF: 21
  • OC02 | INCIDENCE AND PREDICTORS OF ARTERIAL THROMBOSIS IN CANCER PATIENTS: RESULTS FROM THE PROSPECTIVE COMPASS-ARTERIAL CANCER ASSOCIATED THROMBOSIS (COMPASS-ARTECAT) STUDY M. Drakopoulou1, I. Diamandoulaki2, P. Baglaridis1, P. Las Casa3, P. Van Dreden4, K. Toutouzas1, G. Gerotziafas4|5 | 1First Department of Cardiology, School of Medicine, National and Kapodistrian University of Athens, Hippokration General Hospital, Athens, Greece; 2Department of Electrical and Computer Engineering, Aristotle University of Thessaloniki, Thessaloniki, Greece; 3Sorbonne University, INSERM UMR_S_938, CRSA, Research Department "Cancer, Vessels, Biology and Therapeutics" (CaVITE), Research Group "Cancer-Angiogenesis-Thrombosis and Haemostasis," Thrombosis Center, University Institute of Cancerology (UIC), Saint Antoine University Hospital Assistance Publique Hôpitaux de Paris (AP-HP) Paris France; 4Diagnostica Stago, clinical research, Gennevilliers, France; 5Center of Translational Research and Education, Department of Pathology and Laboratory Medicine, Loyola University Stritch School of Medicine, Maywood, Ill., USA

    ICTHIC 2026
    16-04-2026
    https://doi.org/10.4081/btvb.2026.486
    526
    PDF: 136
  • CO-52 | CARDIOVASCULAR EVENTS AND SUBCLINICAL ATHEROSCLEROSIS IN HEMOPHILIA A AND B PATIENTS: A MULTICENTER COHORT STUDY A. Napolitano, E. Zanon, L. Spiezia, G. Camporese, P. Scarinzi, F. Ahmad, G. Saggiorato, C. Bulato, S. Toffanin, S. Gavasso, F. Sartorello, C. Simion, E. Campello, P. Simioni | Hemophilia Center, University Hospital of Padua, Italy

    Angela Napolitano
    14-10-2026
    https://doi.org/10.4081/btvb.2026.662
    59
    PDF: 22
  • PO37 | Single centre experience on anticoagulation in carriers of non-mild inherited thrombophilia: direct oral anticoagulants (DOAC) efficacy and safety M. D’uva1,2, G. La Barba1, G. Montanaro1, M. Di Ianni1,2, P. Ranalli1,2 | 1Hematology Unit, S. Spirito Hospital, Pescara; 2Department of Medicine and Aging Sciences, D’Annunzio University, Chieti, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.300
    664
    PDF: 30
  • PO022 | ARTIFICIAL INTELLIGENCE–ASSISTED PREDICTION OF THROMBOTIC AND HEMORRHAGIC COMPLICATIONS IN PATIENTS TREATED WITH VITAMIN K ANTAGONISTS: A RETROSPECTIVE EXPLORATORY STUDY G. Sottilotta1, F. Misiti2, G. Praticò1, D. Megalizzi1, F. Luise3 | 1UOSD Microcitemie - Emostasi e Trombosi; 3Laboratorio Analisi Grande Ospedale Metropolitano di Reggio Calabria, Italy; 2Associazione Emofilici di Reggio Calabria, Italy

    Gianluca Sottilotta
    26-10-2026
    https://doi.org/10.4081/btvb.2026.838
    69
    PDF: 27
  • PO143 | GENDER DIFFERENCES IN COAGULATION PROFILE IN OBSTRUCTIVE CORONARY ARTERY DISEASE: PRELIMINARY RESULTS FROM AN ANGIOGRAPHICALLY CONTROLLED COHORT STUDY N. Osti1, G. Musuraca1, M. Spizzo2, P. Pattini2, G. Mango2, F. Ambrosani2, G. Poli3, C. Brocco1, C. Angheben1, M. Donini1, F. Presa2, M. Grusse4, P. Van Dreden4, A. Anesi1, G. Lippi3, M. Del Greco1, A. Castagna2, S. Friso2, A. Ferro1, N. Martinelli2 | 1Azienda Sanitaria Universitaria Integrata del Trentino, Trento, Italy; 2Dip. di Medicina, Università di Verona, Verona, Italy; 3Sez. di Biochimica Clinica, Università di Verona, Verona, Italy; 4Clinical Research, Diagnostica STAGO, Gennevillers, France

    Nicola Osti
    26-10-2026
    https://doi.org/10.4081/btvb.2026.959
    56
    PDF: 27
  • Impact of CYP2C19 loss-of-function variants on outcomes in atrial fibrillation patients undergoing percutaneous coronary intervention: rationale and study design of the WOEST-3 genetic substudy

    Simona Chiusolo, Ashley Verburg, Carmela Morizzo, Ron H.N. Van Schaik, Maja Matic, Marieke J.H. Coenen, Michael Maeng, Jurrien ten Berg, Raffaele De Caterina
    28-08-2026
    https://doi.org/10.4081/btvb.2026.421
    1278
    PDF: 134
    APPENDIX: 103
  • CO068 | FACTORS AFFECTING SPONTANEOUS PLATELET AGGREGATION IN HEALTHY SUBJECTS AND PATIENTS WITH STABLE CORONARY ARTERY DISEASE M. Scavone1, A. Fioretti1, C. Ghali1, B. Clerici1, E. Popov2, G.M. Podda1, M. Cattaneo3 | 1Laboratorio di emostasi e trombosi, Dipartimento di Scienze della Salute, Università degli Studi di Milano, Divisione di Medicina Generale II, ASST Santi Paolo e Carlo, Italy; 2National Medical Research Center of Cardiology, Ministry of Health of the Russian Federation, Moscow, Russia; 3Fondazione Arianna Anticoagulazione, Bologna, Italy

    Mariangela Scavone
    26-10-2026
    https://doi.org/10.4081/btvb.2026.770
    79
    PDF: 27
  • PO80 | Heparin-induced thrombocytopenia: a monocentric experience with danaparoid L. D’Innocenzo, S. Sorrentino, M. De Siati, A. Ferretti, E. De Candia | Unit of Haemostasis and Thrombosis Diseases, Fondazione Policlinico Universitario A. Gemelli, IRCCS, Roma, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.349
    714
    PDF: 19
  • PO098 | REAL-WORLD EMERGENCY DEPARTMENT USE OF ANDEXANET ALFA FOR FACTOR XA INHIBITOR REVERSAL: AN ITALIAN COHORT M.P. Donadini1|2, R. Brivio1, S. Bozzato2, L.M. Caiano2, L. Galli2, L. Bertù1, F. Cortellaro2, W. Ageno3 | 1University of Insubria, Varese, Italy; 2ASST Sette Laghi, Varese, Italy; 3University of Padua, Padova, Italy

    Marco Paolo Donadini
    26-10-2026
    https://doi.org/10.4081/btvb.2026.914
    59
    PDF: 27
  • CO038 | PROGNOSTIC PERFORMANCE OF BLEEDING SEVERITY CLASSIFICATIONS IN HOSPITALIZED PATIENTS WITH GASTROINTESTINAL BLEEDING ON DIRECT ORAL ANTICOAGULANTS G. Maraziti, A. Vinci, M. Verso | Internal and Emergency Medicine - Stroke Unit, S. Maria della Misericordia Hospital – University of Perugia, Perugia, Italy

    Giorgio Maraziti
    26-10-2026
    https://doi.org/10.4081/btvb.2026.740
    86
    PDF: 25
  • PO078 | CARDIOVASCULAR EVENTS AND SUBCLINICAL ATHEROSCLEROSIS IN HEMOPHILIA A AND B PATIENTS: A MULTICENTER COHORT STUDY A. Napolitano, E. Zanon, L. Spiezia, G. Camporese, P. Scarinzi, F. Ahmad, G. Saggiorato, C. Bulato, S. Toffanin, S. Gavasso, P. Zerbinati, C. Simion, E. Campello, P. Simioni | Department of Medicine, University of Padova, Italy

    Angela Napolitano
    26-10-2026
    https://doi.org/10.4081/btvb.2026.894
    42
    PDF: 27
  • PO16 | EPIDEMIOLOGY, CLINICAL CHARACTERISTICS, AND OUTCOMES OF PROVOKED AND UNPROVOKED PULMONARY EMBOLISM IN A MULTICULTURAL ISRAELI POPULATION R. Farah1, N.L. Bragazzi2|3|4, H.İ. Ceylan5, Ł. Szarpak6|7|8|9, W. Mahajni1, N. Ashqar1, A. M. Fioretti10, R. Khamisy-Farah11 | 1Internal Medicine B Department, Ziv Medical Center, Azrieli Faculty of Medicine, Bar-Ilan University, Galilee, Safed, Israel; 2Laboratory for Industrial and Applied Mathematics, Department of Mathematics and Statistics, York University, Toronto, Canada; 3Postgraduate School of Public Health, Department of Health Sciences, University of Genoa, Italy; 4UNESCO Chair, Health Anthropology, Biosphere and Healing Systems, University of Genoa, Italy; 5Physical Education and Sports Teaching Department, Faculty of Sports Sciences, Atatürk University, Erzurum, Turkey; 6Department of Clinical Research and Development, LUXMED Group, Warsaw, Poland; 7Institute of Medical Science, Collegium Medicum, The John Paul II Catholic University of Lublin, Lublin, Poland; 8The World Academic Council of Emergency Medicine, Sarasota, FL, USA; 9Henry JN Taub Department of Emergency Medicine, Baylor College of Medicine, Houston, TX, USA; 10Cardio-Oncology Unit, IRCCS Istituto Tumori “Giovanni Paolo II”, Bari, Italy; 11Clalit Health Service, Azrieli Faculty of Medicine, Bar-Ilan University, Galilee, Safed, Israel

    ICTHIC 2026
    16-04-2026
    https://doi.org/10.4081/btvb.2026.511
    458
    PDF: 116
  • PO076 | ACQUIRED FACTOR V INHIBITOR WITH CONCOMITANT LUPUS ANTICOAGULANT: DIAGNOSTIC PITFALLS AND THERAPEUTIC CHALLENGES G. Gazzelli1, Y. Azzanelli1, C. Vernarecci1, F. Marotta1, F. Giacopelli1, E. Cenni2, V. Agostini2, L. Banov1, AC Molinari1 | 1IRCCS Istituto Giannina Gaslini, Italy; 2IRCSS AOM S. Martino Genova, Italy

    Angelo Claudio Molinari
    26-10-2026
    https://doi.org/10.4081/btvb.2026.892
    79
    PDF: 30
  • CO-83 | ACQUIRED FACTOR V DEFICIENCY IN A HIGH-THROMBOTIC-RISK PATIENT: DIAGNOSTIC DILEMMA AND SUCCESSFUL MANAGEMENT G. Gazzelli1, L. Banov1, Y. Azzanelli1, C. Vernarecci1, F. Marotta1, F. Giacopelli1, E. Cenni2, V. Agostini2, A.C. Molinari1 | 1IRCCS Istituto Giannina Gaslini, Italy; 2IRCSS AOM S. Martino, Genova, Italy

    Angelo Claudio Molinari
    14-10-2026
    https://doi.org/10.4081/btvb.2026.693
    68
    PDF: 29
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Vol. 5 No. 4 (2026)
Platelets versus monocytes as cellular sources of blood-borne tissue factor: a quantitative and functional comparison in healthy subjects...
Marina Camera et al.
12 October 2026
Vol. 5 No. 4 (2026)
Von Willebrand Disease (VWD) 100 years after its first description: the research of Italian investigators for a better management of VWD patients
Augusto B. Federici et al.
9 October 2026
Vol. 5 No. 4 (2026)
The history of the TIMI, GISSI, and ISIS trials: the development of thrombolytic therapy in acute myocardial infarction
Aldo Pietro Maggioni et al.
13 October 2026
Vol. 5 No. 4 (2026)
Anticoagulant treatment in patients with internal jugular vein thrombosis: a case serie
Arianna Pannunzio et al.
14 October 2026

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Bleeding, Thrombosis and Vascular Biology

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