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CO025 | HEPHAESTUS: A DIGITAL ATLAS FOR TRAINING AND STANDARDIZATION OF JOINT POINT-OF-CARE ULTRASOUND IN HEMOPHILIC ARTHROPATHY R. Gualtierotti1|2, N. D'Amico3, S. Mascetti3, M. Fassi1, A. Giachi1, C. Bettini3, F. Peyvandi1|2 | 1Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Milano, Italy; 2Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milano, Italy; 3Department of Computer Science, Università degli Studi di Milano, Milano, Italy
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CO100 | ANTIPHOSPHATIDYLSERINE–PROTHROMBIN ANTIBODIES IN ANTIPHOSPHOLIPID SYNDROME: CLINICAL ASSOCIATIONS AND DIAGNOSTIC GAPS MAPPED BY A SCOPING REVIEW H. Parikh1, G. Gobbo2|3, F. Albiero2|3, J. Dass4, E. Esteve-Valverde5|6, J. Alijotas-Reig5|7, P. Simioni2|3, A. Hoxha2|3 | 1Hemato-Oncology Clinic Vedanta, Ahmedabad, India; 2Department of Medicine (DIMED), University of Padua, Italy; 3Internal Medicine Unit and Thrombotic and Bleeding Disorder Centre, University Hospital of Padua, Padova, Italy; 4Department of Hematology, All India Institute of Medical Sciences, New Delhi, India; 5Vall d'Hebron Research Institute, Vall d'Hebron Hospital Campus, Barcelona, Spain; 6Systemic Autoimmune Diseases Unit, Department of Medicine, Hospital Sant Camil, Consorci Sanitari Alt-Penedes-Garraf, Sant Pere de Ribas, Barcelona, Spain; 7Department of Medicine, Universitat Autonoma, Barcelona, Spain
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CO-21 | FUSION 2: VALIDATION AND CLINICAL PERFORMANCE OF AN INTEGRATED ULTRASOUND–FUNCTIONAL ASSESSMENT SYSTEM IN HEMOPHILIA M.E. Susi1, E.A. Boccalandro2, A. Giuffrida3, I. Ricca4, P. Imazio5, E. Bonetti6, I. Nichele7 B. Pollio8, E. Zanon9, E. Baldacci10, C. Santoro10, G. Delios4, S. Ligia10, M. Biglietto10, I. Calcaterra11, M. Napolitano12, M. Bodini2, C. Simion9, B. Borsellino8, G. Pasta13, M.N.D. Di Minno11, C. Martinoli14|15 | 1DIMES, Department of Experimental Medicine, University of Genoa, Italy; 2Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center and Fondazione Luigi Villa, Milano, Italy; 3Hemophilia Center, Borgo Roma Hospital, Integrated University Hospital of Verona, Italy; 4Immunology and Transfusion Medicine Service, Hemophilia Center, Ivrea Hospital, Local Health Authority TO4, Ivrea, Italy; 5Rehabilitation and Functional Recovery Service, Pediatric Orthopedics Unit, Regina Margherita Children’s Hospital, City of Health and Science University Hospital of Turin, Italy; 6Pediatric Oncohematology Unit, Borgo Trento Hospital, Integrated University Hospital of Verona, Italy; 7Haemophilia and Thrombosis Center, Haematology Department, San Bortolo Hospital, Vicenza, Italy; 8Transfusion Medicine and Immunohematology Service, Regina Margherita Children’s Hospital, City of Health and Science University Hospital of Turin, Italy; 9Coagulation Disorders and Hemophilia Center, University Hospital of Padova, Italy; 10Unit of Special Diagnosis and Therapy of Hemostasis and Thrombosis, Hematology Department, Policlinico Umberto I, Sapienza University of Rome, Italy; 11Department of Clinical Medicine and Surgery, Regional Reference Centre for Coagulation Disorders, Federico II University, Napoli, Italy; 12Dipartimento PROMISE, Università degli Studi di Palermo and UOC Ematologia e Malattie Rare, PO “Cervello”, Palermo, Italy; 13Orthopedics and Traumatology Clinic, IRCCS Policlinico San Matteo Foundation, Pavia, Italy; 14DISSAL, Department of Health Sciences, University of Genoa, Italy; 15UOC Emergency and Musculoskeletal Radiology, IRCCS AOM San Martino Hospital, Genova, Italy
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PO61 | RISK FACTORS FOR INTRACRANIAL HEMORRHAGE: AN UMBRELLA REVIEW TO INFORM MACHINE LEARNING PREDICTION MODELS IN GLIOMA PATIENTS RECEIVING ANTICOAGULATION T.A. Adeyemo, S. Greenley, F. Ware, W. Jones, A. Maraveyas, F. Haque | 1Centre of Excellence for Data Science, Artificial Intelligence and Modelling DAIM, Faculty of Science and Engineering, University of Hull, UK; 2Hull York Medical School, Hull, UK; 3Academic Library Services, University of Hull, UK; 4NHS Humber Health Partnership, Hull, UK
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PO114 | A CASE OF ACQUIRED HEMOPHILIA AFTER TAVI AND CORONARY ANGIOPLASTY IN PATIENT WITH ATRIAL FIBRILLATION AND MULTIPLES CARDIOVASCULAR RISK FACTORS – THE ART AND SCIENCE OF THERAPEUTIC CONFLICT M.M. Poggi1, C. Tamburini2, M. Littera2, M. Mazzetti2 | 1SOC Medicina 1, Nuovo Ospedale Prato, Prato, Italy; 2SOD Medicina Interna Interdisciplinare, Azienda Ospedaliera Universitaria Careggi, Firenze, Italy
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CO27 | Intracerebral hemorrhage in hemophilia A and B: a 10-year prospective multicenter study in Italy (2012–2022) E. Zanon1, A. Napolitano1, A. Porreca2, F. Demartis3, A. Coppola4, C. Santoro5, I. Cantori6, A. C. Molinari7, C. Biasioli8, M. Luciani9, G. Sottilotta10, B. Pollio11, A. Borchiellini12, A. Tosetto13, P. Flora14, P. Simioni1 | 1Haemophilia Center, First Chair of Internal Medicine, Department of Medicine, University-Hospital of Padua Medical School, Padua; 2Department of Human Sciences and Promotion of the Quality of Life, Unit of Clinical and Molecular Epidemiology IRCCS San Raffaele Roma Open University, Roma; Unit of Clinical and Molecular Epidemiology IRCCS San Raffaele, Roma; 3Centre for Bleeding Disorders, Careggi University Hospital of Firenze; 4Azienda Ospedaliero Universitaria di Parma; 5Hematology Division, Umberto I University Hospital of Roma; 6Haemophilia Center, Department of Transfusion Medicine, Hospital of Macerata; 7IRCCS Istituto Giannina Gaslini, Genova; 8Haemophilia and Transfusion Centre, Bufalini Hospital, Cesena; 9Children’s Hospital Bambino Gesù, Roma; 10Haemophilia Center, Department of Onco-Hematology and Radioterapy, Hospital of Reggio Calabria; 11Haemophilia Pediatric Center, Transfusion Medicine, City of Health and Science of Turin; 12City of Health and Science of Turin; 13Hemorrhagic and Thrombotic Diseases Unit, S. Bortolo Hospital of Vicenza; 14RCCS Foundation Ca’ Granda Maggiore Policlinico Hospital, Milan, Italy
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CO075 | PLATELET ACTIVATION PROFILE IN RELAPSING-REMITTING MULTIPLE SCLEROSIS AND ITS RELATIONSHIP WITH NEURONAL AND ASTROGLIAL BIOMARKERS A. Fioretti1, M. Scavone1, A. Mingione2|3, C. Monzani2|3, M. Miozzo4, F. Martinelli-Boneschi2|3|5, G.M. Podda1 | 1Division of Medicina Generale SP, ASST Santi Paolo e Carlo, Laboratory of Haemostasis and Thrombosis, Dipartimento di Scienze della Salute, Università degli Studi di Milano, Milano, Italy; 2Laboratory of Precision Medicine of Neurological Diseases, Department of Health Science, University of Milano, Milano, Italy; 3CRC “Aldo Ravelli” for Experimental Brain Therapeutics, Department of Health Science, University of Milano, Milano, Italy; 4Department of Health Sciences, Division of Medical Genetics, University of Milano, ASST Santi Paolo e Carlo, Milano, Italy; 5Clinical Neurology Unit, ASST Santi Paolo e Carlo and Department of Health Sciences, University of Milano, Milano, Italy
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PO09 | CANCER MORTALITY AFTER INCIDENT VENOUS THROMBOEMBOLISM C. Langholm1, N.H. Eide1, K. Hveem2|3|4, N. Van Es5|6, V.M. Morelli1|7, S.K. Braekkan1|7, J.B. Hansen1|7 | 1Thrombosis Research Group, Department of Clinical Medicine, UiT – The Arctic University of Norway, Tromsø, Norway; 2HUNT Research Centre, Department of Public Health and General Practice, Norwegian University of Science and Technology, Levanger, Norway; 3HUNT Center for Molecular and Clinical Epidemiology, Department of Public Health and Nursing, Norwegian University of Science and Technology, Trondheim, Norway; 4Department of Research, St. Olav University Hospital, Trondheim, Norway; 5Department of Vascular Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands; 6Amsterdam Cardiovascular Sciences Pulmonary Hypertension and Thrombosis Amsterdam, the Netherlands; 7Thrombosis Research Center, Department of Internal Medicine, University Hospital of North Norway, Tromsø, Norway
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PO017 | BEYOND IONIC STRENGTH: ANION EFFECTS ON FIBRIN CLOT FORMATION, STRUCTURE, AND MECHANICAL PROPERTIES C. Spoliti1, T. Feller2, F.L. Macrae2, R.A.S. Ariëns2, R. De Cristofaro1|3, E. Di Stasio4|5 | 1Department of Translational Medicine and Surgery, Università Cattolica del Sacro Cuore, Roma, Italy; 2Discovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, United Kingdom; 3Hemorrhagic and Thrombotic Diseases Center, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy; 4Department of Basic Biotechnological Sciences, Intensive Care and Perioperative Clinics, Università Cattolica del Sacro Cuore, Roma, Italy; 5Clinical Chemistry, Biochemistry and Molecular Biology Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy
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PO56 | Safety of anticoagulant treatment in patients with splanchnic vein thrombosis and history of portal hypertension-related bleeding R. Talerico1, S. Pellegrino1, A. Plessier2, F.R. Ponziani3, A. Porfidia1, F. Landi1, A. Gasbarrini3, R. Pola1, F. Santopaolo3 | 1Department of Geriatric, Orthopedic, and Rheumatologic Sciences, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Roma, Italy; 2Université de Paris, AP-HP, C, DMU DIGEST, Centre de Référence des Maladies Vasculaires du Foie, FILFOIE, ERN RARE-LIVE. Centre de recherche sur l’inflammation, Inserm, Paris, France; 3Department of Medical and Surgical Sciences, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Roma, Italy
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PO15 | Venous thromboembolism risk associated with midline catheters and peripherally inserted central catheters: a systematic review and meta-analysis D. Santagata1, F. Subri1, F. Dentali1,2, M.P. Donadini1, I. Giarretta2 | 1Department of Medicine and Surgery, Research Center on Thromboembolic Disorders and Antithrombotic Therapies, University of Insubria, Varese and Como; 2Department of Internal Medicine, Ospedale di Circolo and Fondazione Macchi, Varese, Italy
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CO-47 | JOINT ULTRASOUND FOLLOW-UP IN PEDIATRIC PATIENTS WITH HEMOPHILIA: A 12-YEAR PROSPECTIVE SINGLE-CENTER EXPERIENCE I. Ricca1, B. Borsellino2|3, T. Martini2, C. Martinoli4, B. Pollio2 | 1Transfusion Medicine, Ivrea Hospital, Ivrea, Italy; 2Haemophilia Centre, Immune-Haematology and Transfusion Medicine, University Hospital “Città della Salute e della Scienza”, Torino, Italy; 3Department of Biomedicine and Prevention, PhD in Immunology, Molecular Medicine and Applied Biotechnology, University of Rome Tor Vergata, Roma, Italy; 4Department of Health Science DISSAL, University of Genova, Unit of Radiology and IRCCS San Martino Hospital, Genova, Italy
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CO097 | IMPACT OF THE 2023 ACR/EULAR ANTIPHOSPHOLIPID SYNDROME CRITERIA IN 1200 WOMEN WITH PRIOR OBSTETRIC ANTIPHOSPHOLIPID SYNDROME J. Alijotas-Reig1|2|3, E. Esteve-Valverde4, L. Saez-Comet5, A. Anunciacion-Llunell3, R. Ferrer-Oliveras6, E. Lefkou7, A. Mekinian8, C. Belizna9, A. Hoxha10, A. Tincani11, L. Marozio12, G. Espinosa13, S. de Carolis14, S. Udry15, J.O. Latino15, E. Llurba16, C.B. Chighizola17|18, M. Gerosa19, V. Pengo20, K. Lundelin21, P. Rovere-Querini22, V. Canti22, K. Mayer-Pickel23, T. Reshetnyak24, S. Tabacco25, L. Stojanovich26, B.A. Gonçalves27, S. Morales-Perez1, F. Miro-Mur3 | 1Department of Medicine, Universitat Autonoma de Barcelona, Spain; 2Systemic Autoimmune Disease Unit, Department of Internal Medicine, Vall d’Hebron University Hospital, Spain; 3Systemic Autoimmune Diseases Research Unit, Vall d’Hebron Institut de Recerca, Barcelona, Spain; 4Systemic Autoimmune Diseases Unit, Department of Internal Medicine, Hospital Sant Camil, Consorci Sanitari del Garraf, Barcelona, Spain; 5Department of Internal Medicine, Hospital Universitario Miguel Servet, Zaragoza, Spain; 6Obstetrics Department, High-Risk Unit, Hospital Universitario Quironsalud, Barcelona, Spain; 7Haematology Unit, Hippokration Hospital of Thessaloniki, Greece; 8AP-HP, Hopital Saint-Antoine, Service de Medecine Interne and Inflammation-Immunopathology-Biotherapy Department (DHU i2B), Sorbonne Universites, Paris, France; 9Vascular and Coagulation Department, University Hospital Angers, Angers, France; 10Internal Medicine Unit, Thrombotic and Bleeding Disorder Center, University of Padua, Padova, Italy; 11Department of Clinical and Experimental Sciences, University of Brescia, Spedali Civili, Brescia, Italy; 12Department of Obstetrics and Gynaecology, Universita di Torino, Torino, Italy; 13Systemic Autoimmune Diseases Service, Hospital Clínic, Universitat de Barcelona, Barcelona, Spain; 14Department of Gynaecology, Gemelli Hospital, Catholic University, Roma, Italy; 15Autoimmune, Thrombophilic Diseases and Pregnancy Division, Dr. Carlos G. Durand Hospital, Buenos Aires, Argentina; 16Obstetrics and Gynaecology Department, High-Risk Unit, University Hospital de la Santa Creu i Sant Pau, Barcelona, Spain; 17Department of Clinical Science and Community Health, University of Milano, Milano, Italy; 18Unit of Pediatric Rheumatology, ASST G. Pini-CTO, Milano, Italy; 19Division of Rheumatology, Department of Clinical Sciences and Community Health, University of Milano, Milano, Italy; 20Cardiology Unit, Department of Cardiac, Thoracic and Vascular Sciences, University of Padua, Padova, Italy; 21Department of Pediatrics, Faculty of Medicine, University of Turku, Turku, Finland; 22Internal Medicine and Division of Immunology, Transplantation and Infectious Diseases, IRCCS Ospedale San Raffaele, Milano, Italy; 23Department of Obstetrics, Medical University of Graz, Graz, Austria; 24Department of Systemic Rheumatic Disease, V. A. Nasonova Research Institute of Rheumatology, Moscow, Russia; 25Department of Gynecology, Obstetrics and Urology, Sapienza University of Roma, Roma, Italy; 26University Medical Center, University of Belgrade, Belgrade, Serbia; 27Department of Internal Medicine, Hospital Sant Joan Despí Moises-Broggi, Barcelona, Spain
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PO05 | Intensive FVIII replacement in haemophilia patients with hypertrophic synovium: a randomized study I.L. Calcaterra1, E. Baldacci2, R. Marino3, F. Valeri4, R.C. Santoro5, G. Pasta6, C. Martinoli7, M. Di Minno1 | 1Department of Clinical Medicine and Surgery, Federico II University, Naples; 2Haematology, University Hospital Policlinico Umberto I, Roma; 3Haemophilia Center and thrombosis, Policlinico, Bari; 4Regional Centre for Haemorrhagic and Thrombotic Diseases, AOU Città Della Salute e Della Scienza; Turin; 5Centre for Hemorrhagic and Thrombotic Disorders, Pugliese Ciaccio Hospital, Catanzaro; 6Fondazione IRCCS San Matteo Hospital, Pavia; 7Department of Health Science DISSAL, University of Genoa, Unit of Radiology and IRCCS San Martino Hospital, Genoa, Italy
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PO62 | CLINICAL AND MOLECULAR DIAGNOSTIC CHALLENGES IN MYELOPROLIFERATIVE NEOPLASMS WITH LOW JAK2V617F ALLELIC BURDEN E. Morsia, D. Lame, M. Pianelli, G. Gramazio, R. Ceccarelli, I. Battilà, S. Rupoli, A. Poloni | Department of Clinical and Molecular Science, Università Politecnica delle Marche, Ancona, Italy
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CO081 | RESTORATION OF CEREBRAL MICROVASCULAR STRUCTURE AND FUNCTION IN HEMOPHILIA A MICE THROUGH FVIII GENE THERAPY G. Venturin1, E. Spicuglia1, S. Assanelli1, C. Borsotti1, A. Cucci1, N. Keivan1, E. Borroni1, C. Sgromo1, C. Olgasi2, A. Follenzi1|3 | 1Department of Health Science, Università del Piemonte Orientale, Novara, 28100, Italy; 2Department of Translational Medicine, Università del Piemonte Orientale, Novara, 28100, Italy; 3Department of Attività Integrate Ricerca Innovazione, Azienda Ospedaliero-Universitaria SS. Antonio e Biagio e C. Arrigo, Alessandria, Italy
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CO28 | Cognitive, adaptive abilities and behavioral symptoms in children and adolescents with hemophilia: a pilot study R. Vallone1, M. Luciani2, A. Smigliani2, M. F. Mansueto3, S. Vicari1,4, D. Menghini1 | 1Child and Adolescent Neuropsychiatry Unit, Bambino Gesù Children’s Hospital, IRCCS, Roma; 2OncoHematology Unit, Bambino Gesù Children’s Hospital, IRCCS, Roma; 3Department of Oncology U.O. Hematology AUO Policlinico, Paolo Giaccone, Palermo; 4Department of Life Science and Public Health, Università Cattolica del Sacro Cuore, Roma, Italy
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Still unmet problems with low molecular weight heparin prophylaxis of venous thromboembolism. An Italian survey
1449PDF: 309HTML: 206Supplementary: 103 -
CO077 | PLATELET MIR-144-5P REGULATES COX-1/2 EXPRESSION AND MODULATES ASPIRIN RESPONSE IN PATIENTS WITH CARDIOMETABOLIC RISK P. Simeone1, R. Liani1, V. Abbonante2, M. Alfonsetti1, M. Frezza1, P. Lanuti1, A. Recchiuti3, A. Balduini2, F. Santilli1 | 1Department of Medicine and Aging, and Center for Advanced Studies and Technology (CAST), "G. d'Annunzio" University of Chieti-Pescara, Chieti, Italy; 2Department of Molecular Medicine, University of Pavia, Pavia, Italy; 3Department of Medical, Oral, and Biotechnological Science, Center for Advanced Studies and Technology (CAST), "G. d'Annunzio" University of Chieti-Pescara, Chieti, Italy
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PO57 | A NOVEL RISK ASSESSMENT MODEL FOR CANCER DETECTION WITHIN ONE YEAR AFTER INCIDENT VENOUS THROMBOEMBOLISM C. Antoun1, J. Hansen1|3, S. Brækkan1|3, C. Langholm1, N. Eide1, V. Morelli1|3, K. Hveem2 | 1Department of Clinical Medicine, UiT The Arctic University of Norway, Tromsø; 2HUNT Center for Molecular and Clinical Epidemiology, Norwegian University of Science and Technology, Trondheim; 3Thrombosis Research Center, Division of Internal Medicine, University Hospital of North Norway, Tromsø, Norway
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PO038 | GLOBAL IMPLEMENTATION AND CLINICAL USE OF POINT-OF-CARE JOINT ULTRASOUND IN HEMOPHILIA: RESULTS FROM AN INTERNATIONAL SURVEY R. Gualtierotti1|2, C. Tedesco1, S. Acharya3, N. Bakeer4, M.N.D. Di Minno5, M. Fassi1, A. von Drygalski6, K. Fijnvandraat7, A. Boban8, C. Martinoli9|10, N. O'connell11, M. Sigl-Kraetzig12, A. Srivastava13, F. Peyvandi1|2 | 1Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Milano, Italy; 2Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milano, Italy; 3Division of Pediatric Hematology, Oncology and Stem Cell Transplant, Cohen Children's Medical Center, Northwell Health, New York, United States; 4Division of Hematology, Children's Hospital of Philadelphia, Philadelphia, United States; 5Department of Clinical Medicine and Surgery, Federico II University, Napoli, Italy; 6Division of Hematology/Oncology, Department of Medicine, University of California San Diego, La Jolla, United States; 7Emma Children's Hospital, Pediatric Hematology, University of Amsterdam, Amsterdam, The Netherlands; 8Haemophilia Centre, Department of Haematology, University Hospital Centre Zagreb, Zagreb, Croatia; 9Department of Health Science, University of Genoa, Genova, Italy; 10istituto di Ricovero e Cura a Carattere Scientifico San Martino Hospital, Unit of Radiology, Genova, Italy; 11National Coagulation Centre, St. James's Hospital, Dublin, Ireland; 12Institute for Paediatric Research and Further Education, Blaubeuren, Germany; 13Haematology Research Unit, St. John's Research Institute & Department of Clinical Haematology, St. John's Medical College Hospital, Bengaluru, India
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PO88 | Bacterial lysate “lantigen B” induces proliferation of B and NK cells and the release of related cytokines M. Alfonsetti1, R. Liani1, P. Di Mattia3, M. Tredicine4, F. Papa3, Q. Niu5, M. Di Gioacchino2, F. Santilli1,3 | 1Department of Medicine and Aging, Center for Advanced Studies and Technology, University of Chieti, Italy; 2Institute for Clinical Immunotherapy and Advanced Biological Treatments, Pescara, Italy; 3Specialization School of Allergy and Clinical Immunology, G. d’Annunzio University, Chieti, Italy; 4Department of Medical, Oral, and Biotechnology Science, University G. d’Annunzio, Chieti-Pescara, Chieti, Italy; 5Department of Occupational Health, School of Public Health, Shanxi Medical University, Taiyuan, Shanxi, China
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CS05 | Joint ultrasound follow-up in pediatric patients with haemophilia: a 12-year prospective single-center experience B. Borsellino1,2, B. Pollio1, C. Martinoli3, T. Martini1, R. Albiani1, I. Ricca1 | 1Haemophilia Centre, Immune-Haematology and Transfusion Medicine, University Hospital “Città della Salute e della Scienza”, Turin; 2Department of Biomedicine and Prevention, PhD in Immunology, Molecular Medicine and Applied Biotechnology, University of Roma Tor Vergata, Roma; 3Department of Health Science DISSAL, University of Genoa, Unit of Radiology and IRCCS San Martino Hospital, Genoa, Italy
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PO16 | EPIDEMIOLOGY, CLINICAL CHARACTERISTICS, AND OUTCOMES OF PROVOKED AND UNPROVOKED PULMONARY EMBOLISM IN A MULTICULTURAL ISRAELI POPULATION R. Farah1, N.L. Bragazzi2|3|4, H.İ. Ceylan5, Ł. Szarpak6|7|8|9, W. Mahajni1, N. Ashqar1, A. M. Fioretti10, R. Khamisy-Farah11 | 1Internal Medicine B Department, Ziv Medical Center, Azrieli Faculty of Medicine, Bar-Ilan University, Galilee, Safed, Israel; 2Laboratory for Industrial and Applied Mathematics, Department of Mathematics and Statistics, York University, Toronto, Canada; 3Postgraduate School of Public Health, Department of Health Sciences, University of Genoa, Italy; 4UNESCO Chair, Health Anthropology, Biosphere and Healing Systems, University of Genoa, Italy; 5Physical Education and Sports Teaching Department, Faculty of Sports Sciences, Atatürk University, Erzurum, Turkey; 6Department of Clinical Research and Development, LUXMED Group, Warsaw, Poland; 7Institute of Medical Science, Collegium Medicum, The John Paul II Catholic University of Lublin, Lublin, Poland; 8The World Academic Council of Emergency Medicine, Sarasota, FL, USA; 9Henry JN Taub Department of Emergency Medicine, Baylor College of Medicine, Houston, TX, USA; 10Cardio-Oncology Unit, IRCCS Istituto Tumori “Giovanni Paolo II”, Bari, Italy; 11Clalit Health Service, Azrieli Faculty of Medicine, Bar-Ilan University, Galilee, Safed, Israel
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PO037 | TEMPO: A MOBILE HEALTH APPLICATION FOR PERSONALIZED MANAGEMENT OF HEMOPHILIA R. Gualtierotti1|2, F. Franco3, L. Bedogni4, M. Fassi1, A.A Giachi1, S. Mascetti5, M. Manzoni5, F. Poggi6, M. Pellegrini6, C. Suffritti1, F. Peyvandi1|2 | 1Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Milano, Italy; 2Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milano, Italy; 3Department of Physics, Informatics and Mathematics (FIM), University of Modena and Reggio Emilia, Modena, Italy; 4Department of Sciences and Method for Engineering (DISMI), University of Modena and Reggio Emilia, Modena, Italy; 5Department of Computer Science, Università degli Studi di Milano, Milano, Italy; 6Institute for Cognitive Sciences and Technologies (ISTC), National Research Council (CNR), Bologna, Italy
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PO79 | Trying to hit the hit in the shadow of renal failure: a complex case managed with danaparoid S. Chessa1,2, M. Anedda2, M.V. Cherchi2, M. Vacca1,2, M. Caboni2, J. Pilia2, A.M. Bussu2, M. Mantega2, G. Costanzo1, D. Firinu1, S. Del Giacco1, A. Mameli3, D. Barcellona3 | 1Department of Medical Science and Public Health, University of Cagliari; 2Internal Medicine, ASL Sulcis, PO Sirai, Carbonia; 3Department of Medical Sciences and Public Health, Hemostasis and Thrombosis Unit, University of Cagliari and AOU of Cagliari, Italy
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Whole exome sequencing in a family with thromboangiitis obliterans
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CO042 | BLEEDING RISK IN PATIENTS RECEIVING CONCURRENT TREATMENT WITH DIRECT ORAL ANTICOAGULANTS AND CORTICOSTEROIDS: A SYSTEMATIC REVIEW M.A. Capparella1, R. Talerico2, C. Cavallaro2, M. Iorio2, F. Bossi1, A. Porfidia2, K. Abe3, M. Biglietto4, A. Chistolini4, A. Holt5, L. Lahousse6|7, R. Pola2, C. Becattini1, M.C. Vedovati1 | 1Internal, Vascular and Emergency Medicine – Stroke Unit, University of Perugia, Italy; 2Thrombosis Unit, Department of Geriatric, Orthopedic, and Rheumatologic Sciences, Fondazione Policlinico A. Gemelli IRCCS, Roma, Italy; 3Division of Gastroenterology, Department of Medicine, Teikyo University School of Medicine, Tokyo, Japan; 4Hematology, Department of Translational and Precision Medicine, Sapienza University of Roma, Italy; 5Department of Cardiology, Copenhagen University Hospital – Herlev and Gentofte, Copenhagen, Denmark; 6Department of Bioanalysis, Pharmaceutical Care Unit, Faculty of Pharmaceutical Sciences, Ghent University, Ghent, Belgium; 7Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands
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CS02 | Functional and structural impairments of the cerebral microcirculation in a mouse model of hemophilia A G. Venturin1, C. Olgasi2, C. Borsotti1, P.E. Di Simone1, E. Spicuglia1 A. Cucci1, C. Sgromo1, A. Follenzi2,3 | 1Department of Health Science, Università del Piemonte Orientale, Novara; 2Department of Translational Medicine, Università del Piemonte Orientale, Novara; 3Department of Attività Integrate Ricerca Innovazione, Azienda Ospedaliero-Universitaria SS. Antonio e Biagio e C. Arrigo, Alessandria, Italy
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