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Bleeding, Thrombosis and Vascular Biology

Editor-in-Chief: Giovanni de Gaetano, Italy | eISSN: 2785-5309

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  • Diagnostic and management practices for inherited fibrinogen disorders: a nationwide survey of Italian Hemophilia Treatment Centers

    Renato Marino, Silvia Linari, Marzia Leotta, Antonio Coppola, Chiara Biasoli, Maria Elisa Mancuso, Flora Peyvandi, Cristina Santoro, Ezio Zanon, Rita Carlotta Santoro
    02-12-2025
    https://doi.org/10.4081/btvb.2025.372
    428
    PDF: 60
    HTML: 44
    Supplementary: 20
    Appendix: 34
  • Anticoagulation in obese patients: challenges and strategies

    Alice Lipari, Esmeralda Capristo, Antonietta Ferretti, Erica De Candia
    18-09-2025
    https://doi.org/10.4081/btvb.2025.174
    1834
    PDF: 264
    HTML: 196
    XML: 78
  • PO24 | Emicizumab prophylaxis and bleeding outcomes: a single center clinical experience A. Taglietti1, S. Ligia1, F. Paoletti1, R. Mormile1, E. Baldacci2, A. Chistolini1, C. Santoro1,2 | 1Hematology, Department of Translational and Precision Medicine, Sapienza University of Roma; 2Hematology, Azienda Ospedaliera Universitaria Policlinico Umberto I, Roma, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.285
    477
    PDF: 0
  • Preface to the 13th International Conference on Thrombosis and Hemostasis Issues in Cancer, 2026

    Anna Falanga, Benjamin Brenner, Alok A. Khorana
    16-04-2026
    https://doi.org/10.4081/btvb.2026.479
    104
    PDF: 65
  • PO86 | Emicizumab in patients with moderate hemophilia A and severe bleeding phenotype: single-center real-world experience A.L. Faccini, M. Biglietto, S. Sorella, E. Crisanti, M. Antonacci, R. Mormile, R. Ciciani, E. Baldacci, C. Santoro, S. Ligia | Hematology, Department of Translational and Precision Medicine Sapienza University of Roma, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.355
    612
    PDF: 0
  • PO53 | PHASE 3 TRIAL EVALUATING THE EFFICACY AND SAFETY OF REGN7508CAT FOR PRIMARY PROPHYLAXIS OF CANCER-ASSOCIATED THROMBOSIS FOR PARTICIPANTS WITH SOLID TUMORS UNDERGOING CANCER TREATMENT (ROXI-CAT-I) J. Zwicker1, M. P. O’Brien2, M. Carrier3, J. Connors4, A. Falanga5, A. Manzano6, R. Mcbane7, Y.Y. Janjigian1, G. O’Kane8, M. Onisko2, J. Kaplan2, A.P. Kithcart2, D.E. Gutstein2, A. Khorana9, M. F. Walsh2 | 1Memorial Sloan Kettering Cancer Center, New York, USA; 2Regeneron Pharmaceuticals, Inc. , Tarrytown, NY, USA; 3University of Ottawa, Ottawa, ON, Canada; 4Harvard Medical School, Boston, MA, USA; 5Hospital Papa Giovanni XXIII, Bergamo, Italy; 6Hospital Universitario 12 de Octubre, Madrid, Spain; 7Mayo Clinic, Rochester, MN, USA; 8St. Vincent's University Hospital and School of Medicine, University College Dublin, Dublin, Ireland; 9James P. Wilmot Cancer Center and the Department of Medicine, University of Rochester, Rochester, NY, USA

    Società Italiana di Emostasi e Trombosi
    16-04-2026
    https://doi.org/10.4081/btvb.2026.545
    64
    PDF: 16
  • PO82 | Retrospective application of the TH2 score in a multicenter cohort of ITP patients: a reliable predictive tool or a score in need of refinement? C. Giubbilei1, M. Defina2, S. Rosati3, M. Rocco3, A. Votto4, F. Simonetti5, F. Paoletti6, V. Carrai1 | 1Hematology Unit, AOU Careggi; 2Hematology unit AOU Senese; 3Hematology Unit Azienda Sanitaria Toscana Centro; 4Hematology Unit, AOU Pisana; 5Hematology Unit, Ospedale Versilia; 6Hematology Unit, Azienda Sanitaria Nord Ovest, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.351
    449
    PDF: 0
  • Bleeding and thrombosis in patients receiving chimeric antigen receptor T-cell therapy

    Dana Lee, Pedro Luiz Lage Bodour Danielian, Avi Leader
    16-04-2026
    https://doi.org/10.4081/btvb.2026.461
    60
    PDF: 33
  • CO07 | Real word management of anticoagulant therapy in brain metastasis: moving toward a multidisciplinary approach in complex cases E. Lotti1, C. Manneschi2, S. Fancelli2, F. Scolari1, F. Crudele1, D. Poli1, M. Berteotti1, D. Rossini3, S. Pillozzi2, L. Antonuzzo2,3, R. Marcucci1,3 | 1Disease Unit, Careggi University Hospital, Firenze; 2Oncology Unit, Careggi University Hospital, Firenze; <sup>3</sup>Department of Experimental and Clinical Biomedical Sciences, University of Firenze, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.211
    510
    PDF: 0
  • PO25 | EVOLUTION OF ANTICOAGULANT STRATEGIES AND CLINICAL OUTCOMES IN CANCER-ASSOCIATED THROMBOSIS: A LONGITUDINAL ANALYSIS OF THE START2 REGISTRY ONCO-VTE M. Marchetti1|2, T. Zollner1|2, OC. Cretu1|2, A. Chistolini3, R. Pancani4, L. Puccetti5, P. Sivera6, W. Ageno7, G. Elmi8, V. Fregoni9, V. Tonelli10, E. Antonucci11, D. Poli11|12, A. Falanga1|2, L. Barcella1|2 | 1Hemostasis & Thrombosis Center, Department of Transfusion Medicine, Papa Giovanni XXIII Hospital, Bergamo Italy; 2ERN EuroBloodNet; 3Hematology Unit, Department of Translational and Precision Medicine, Sapienza University of Rome, Rome, Italy; 4Pulmonary Unit, Hospital of Siena, University of Siena, Siena, Italy; 5Hemostasis and Thrombosis Unit, Hospital of Siena, University of Siena, Siena, Italy; 6Haematology Unit, Ordine Mauriziano Hospital, Turin, Italy; 7Department of Medicine, University of Padua, Padua, Italy; 8Department of Medicine, Maggiore Hospital, Bologna, Italy; 9Department of Medicine, Sondalo Hospital, Sondalo, Italy; 10Angiology Unit, Sant'Eugenio Hospital, Rome, Italy; 11Arianna Anticoagulazione Foundation, Bologna, Italy; 12Department of Critical Care Medicine, Thrombosis Centre, Azienda Ospedaliera Universitaria Careggi, Firenze, Italy

    Società Italiana di Emostasi e Trombosi
    16-04-2026
    https://doi.org/10.4081/btvb.2026.520
    66
    PDF: 19
  • PO50 | Treatment with BTK inhibitors in patients affected by chronic lymphocytic leukemia: safety and hemostasis L. Gurgoglione, C.A. Piro, I. Scortechini, I. Battilà, M.C. Merlo, A. R. Scortechini, S. Rupoli, A. Poloni | Hematology Unit, AOU delle Marche-Università Politecnica delle Marche, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.319
    399
    PDF: 0
  • PO32 | ANTICOAGULANT THROMBOPROPHYLAXIS IN AGGRESSIVE LYMPHOMAS PATIENTS: PREDICTIVE THROMBOTIC RISK SCORES AND RISK FACTORS L. Gurgoglione1, G. Gini1, S. Rupoli1, A. Poloni1|2 | 1Hematology, AOU delle Marche, Ancona; 2Università Politecnica delle Marche, Ancona, Italy

    Società Italiana di Emostasi e Trombosi
    16-04-2026
    https://doi.org/10.4081/btvb.2026.527
    56
    PDF: 17
  • PO12 | Characterisation and real word clinical data of HEM006, a newly formulated intranasal spray desmopressin (DDAVP) to address a global treatment gap G. De Giorgi1, A. Gringeri2, R. Franceschini1, A. Koganti3 | 1Hemorare Srl, Italy; 2Fondazione Charta, Milan, Italy; 3Quenya LLC, USA

    22-10-2025
    https://doi.org/10.4081/btvb.2025.274
    435
    PDF: 0
  • PO31 | Comparative analysis of anticoagulant therapy in patients over 90 years old: vitamin K antagonists versus direct oral anticoagulants G. Sottilotta1, P. Arrigo2, S. Cuzzocrea1, D. Megalizzi1, F. Luise3 | 1UOSD Microcitemie, Emostasi e Trombosi, Grande Ospedale Metropolitano di Reggio Calabria; 2Associazione Italiana Pazienti Anticoagulati, Sezione di Reggio Calabria; 3Laboratorio Analisi. Grande Ospedale Metropolitano di Reggio Calabria, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.292
    448
    PDF: 0
  • PO43 | Extended treatment with reduced dose of direct oral anticoagulants in patients with venous thromboembolism: a retrospective study A. Pannunzio1, E. Valeriani1, I.M. Palumbo1, D. Menichelli1, T. Brogi2, S. Marucci2, D. Pastori2, P. Pignatelli2 | 1Department of General Surgery and Surgical Specialty, Sapienza University of Roma; 2Department of Clinical Internal, Anesthesiological and Cardiovascular Sciences, Sapienza University of Roma, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.306
    500
    PDF: 0
  • CO04 | Direct oral anticoagulants in antiphospholipid syndrome: a single center real-life experience A. Hoxha1, E. Campello1, F. Ahmad2, L. Spiezia1, P. Scarinzi1, G. Gobbo1, S. Gavasso1, F. Sartorello1, C. Simion1, E. Zanon1, P. Simioni1 | 1Internal Medicine Unit, Thrombotic and Haemorrhagic Centre, Department of Medicine - DIMED; 2Department of Statistical Sciences) University of Padova, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.209
    608
    PDF: 0
  • Bleeding complications of oral anticoagulant therapy: from ISCOAT to the START Register A memory of Gualtiero Palareti

    Francesco Marongiu
    10-04-2026
    https://doi.org/10.4081/btvb.2026.457
    50
    PDF: 23
  • PO18 | THE THROMBO-INFLAMMATION AXIS AS PREDICTOR OF TOXICITY IN PATIENTS TREATED WITH CAR-T CELLS C. Fernández-Arias1, M. Marcos-Jubilar1, M. Panizo1, C. Vázquez-Puerta2, J.R. González-Porras2, M. Ibáñez1, A. Queralt1, M. Carrasco1, M.B. Villacrés1, C. Conde1, P. Elizalde1, S. Huerga1, A. Alfonso1, P. Rodríguez-Otero1, S. Villar1, M.A. Canales1, J. Rifón1, F. Prósper1, J.A. Páramo1, J. Orbe1, R. Lecumberri1 | 1Clínica Universidad de Navarra, Pamplona; 2Hospital Clínico Universitario de Salamanca, Salamanca, Spain

    Società Italiana di Emostasi e Trombosi
    16-04-2026
    https://doi.org/10.4081/btvb.2026.513
    68
    PDF: 19
  • Executive summary of the SISET position paper on the management of antithrombotic therapy in left ventricular thrombus

    Emanuele Valeriani, Arianna Pannunzio, Danilo Menichelli, Domenico Prisco, Walter Ageno, Daniele Pastori, Pasquale Pignatelli
    16-12-2025
    https://doi.org/10.4081/btvb.2025.401
    267
    PDF: 58
    HTML: 19
  • CO40 | The co-inheritance of two ITGB3 variants exerting additive detrimental effects on platelets leads to variant Glanzmann thrombasthenia N. Arndt1, E. Falcinelli1, A. Zamora-Cánovas2, A. Sánchez Fuentes2, A. Marín-Quilez2, I. Tano1, M.D.M. Nieto-Hernández3, J.M. Bastida4, J. Rivera2, P. Gresele1, L. Bury1 | 1Department of Medicine and Surgery, Section of Internal and Cardiovascular Medicine, University of Perugia, Italy; 2Servicio de Hematología y Oncología Médica, Hospital Universitario Morales Meseguer, Centro Regional de Hemodonación, Universidad de Murcia, IMIB-Pascual Parrilla, ISCIII-CIBERER, Murcia, Spain; 3Servicio de Hematología, Hospital Universitario de Jaen, Spain; 4Departamento de Hematología, Complejo Asistencial Universitario de Salamanca “CAUSA”, Instituto de Investigación Biomédica de Salamanca “IBSAL”, Centro de Investigación del Cáncer, IBMCC-CSIC, Universidad de Salamanca “USAL”, Salamanca, Spain

    22-10-2025
    https://doi.org/10.4081/btvb.2025.247
    474
    PDF: 0
  • PO40 | RADAR, UK-MRA MYELOMA XV - COMPARING MRD-GUIDED TREATMENT ESCALATION AND DE-ESCALATION STRATEGIES IN PATIENTS WITH NEWLY DIAGNOSED MYELOMA SUITABLE FOR STEM CELL TRANSPLANTATION: THROMBOPROPHYLAXIS SUBGROUP STUDY PROTOCOL Z. Sayar, on behalf of the RADAR Investigators | Whittington Health NHS Trust and Royal Free Hospital, London, UK

    Società Italiana di Emostasi e Trombosi
    16-04-2026
    https://doi.org/10.4081/btvb.2026.534
    64
    PDF: 15
  • 29th National Conference of the Italian Society for the Study of Hemostasis and Thrombosis, 2025

    Guest Editor: Valerio De Stefano
    22-10-2025
    https://doi.org/10.4081/btvb.2025.408
    697
  • PO35 | A MULTICENTRE AUDIT OF CURRENT TUMOUR THROMBOSIS MANAGEMENT IN THE UNITED KINGDOM A.A. Bhatti1, L. Tafesh1, A. Waton1, M. Thomas3, N. Prasannan3, A. Bhide3, R. Walsh3, T. Lucas3, K. White4, T. Bariana4, O. Tsiamita4, S. Soman4, P. Woolley5, I. Lacej5, K. Musgrave1|2 | 1Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK; 2Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK; 3University College London Hospitals NHS Foundation Trust, London, UK; 4Barts Health NHS Trust, London, UK; 5Imperial College Healthcare NHS Trust, London, UK

    Società Italiana di Emostasi e Trombosi
    16-04-2026
    https://doi.org/10.4081/btvb.2026.529
    74
    PDF: 14
  • Management of anticoagulation in atrial fibrillation patients in Italy: insight from the Atrial Fibrillation-Survey on Anticoagulated Patients Register (AF-START)

    Daniela Poli, Walter Ageno, Emilia Antonucci, Salvatore Bradamante, Eugenio Bucherini, Paolo Chiarugi, Antonio Chistolini, Benilde Cosmi, Anna Falanga, Antonio Insana, Domenico Lione, Rosa Maria Lombardi, Giuseppe Malcangi, Rossella Marcucci, Giuliana Martini, Lucilla Masciocco, Carmelo Paparo, Daniele Pastori, Simona Pedrini, Vittorio Pengo, Pasquale Pignatelli, Andrea Toma, Sophie Testa, Gualtiero Palareti
    27-06-2023
    https://doi.org/10.4081/btvb.2023.84
    1799
    PDF: 511
    Supplementary File: 235
  • PO59 | Efficacy and safety of different anticoagulant treatment regimens for isolated internal jugular vein thrombosis: a case series A. Pannunzio1, E. Valeriani1, I.M. Palumbo1, S. Marucci2, D. Menichelli1, D. Pastori2, P. Pignatelli2 | 1Department of General Surgery and Surgical Specialty, Sapienza University of Roma; 2Department of Clinical, Internal Medicine, Anaesthesiological and Cardiovascular Sciences, Sapienza University of Roma, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.328
    486
    PDF: 0
  • PO41 | VENOUS THROMBOEMBOLISM IN PERIPHERAL BLOOD STEM CELL COLLECTION. A SINGLE CENTER EXPERIENCE P. Holly1, J. Hudecek1, J. Chudej1, L. Valekova1, I. Plamenova1, E. Flochova1, R. Simonova1, J. Sokol1, J. Stasko1, M. Pietrzykova1|2, E. Vescecikova2 | 1Department of Hematology and Transfusion Medicine, University Hospital in Martin, Martin, Slovakia; 2National Transfusion Service, Martin, Slovakia

    Società Italiana di Emostasi e Trombosi
    16-04-2026
    https://doi.org/10.4081/btvb.2026.535
    57
    PDF: 15
  • Thrombosis and hemostasis at the University of Padua: a reappraisal on the occasion of its 800th year of history

    Paolo Simioni, Vittorio Pengo, Paolo Prandoni
    07-11-2022
    https://doi.org/10.4081/btvb.2022.52
    2499
    PDF: 354
  • OC11 | COMPLEXITIES IN MANAGING ANTITHROMBOTIC THERAPY IN PATIENTS WITH CANCER APPROACHING END-OF-LIFE: A MIXED METHOD INTEGRATION USING JOINT DISPLAY ANALYSIS E. Baddeley1, L. Van’t Walderveen2, H. Enggaard3, M. Søgaard4, D. Abbel2, S. Cannegieter2, M. Edwards1, C. Font5, J. Goedegebuur2, F.A. Klok2, K.J. Lifford1, I. Mahé6, S.P. Mooijaart2, S.I.R. Noble1, M. Pearson7, K. Seddon1, S. Sivell1, S. Szmit8, S Trompet2, A.A. Højen4 | 1Cardiff University, Cardiff, UK; 2Leiden University Medical Center, Leiden, The Netherlands; 3Aalborg University Hospital, Aalborg, Denmark; 4Aalborg University and Aalborg University Hospital, Aalborg, Denmark; 5Hospital Clinic Barcelona, Barcelona, Spain; 6Paris Cité Université, Paris, France; 7Hull York Medical School, Hull, UK; 8Centre of Postgraduate Medical Education, Warsaw, Poland

    Società Italiana di Emostasi e Trombosi
    16-04-2026
    https://doi.org/10.4081/btvb.2026.494
    53
    PDF: 20
  • OC03 | THROMBOEMBOLIC PREVALENCE IN MULTIPLE MYELOMA BEFORE AND AFTER THE INTRODUCTION OF DIRECT ORAL ANTICOAGULANTS: A LONGITUDINAL COHORT STUDY A. Ramírez1, A. Orozco2, A. Sánchez3, F. Villalpa1, S. Burgos2, G. Cesarman3, G. Rodríguez1, D. Vieyra2, J. Álvarez4, G.M. Flores3, S. González1, D. Martínez2, B. Cabello3, R. Espinoza3, O. Fernández3 | 1Myeloma-clinic Hematology service, Centro Médico Nacional La Raza, Instituto Mexicano del Seguro Social, México City, México; 2Myeloma-clinic Hematology service, Instituto Nacional de Nutrición Salvador Zubirán, México City, México; 3Myeloma-clinic Hematology service, Instituto Nacional de Cancerologçia, México City, Mexico; 4Centro Médico Nacional 20 de Noviembre, México City, Mexico

    Società Italiana di Emostasi e Trombosi
    16-04-2026
    https://doi.org/10.4081/btvb.2026.487
    49
    PDF: 17
  • PO28 | Long term effectiveness and safety of venous thromboembolism with fondaparinux: data from the start registry I.M. Palumbo1, E. Valeriani1,2, A. Pannunzio1, S. Marucci3, D. Menichelli1, D. Pastori3,4, P. Pignatelli3 | 1Department of General Surgery and Surgical Specialty, Sapienza University of Roma; 2Department of Infectious Disease, Azienda Ospedaliero-Universitaria Policlinico Umberto I, Roma; 3Department of Clinical Internal, Anaesthesiologic and Cardiovascular Sciences, Sapienza University of Roma, Roma; 4IRCCS NeuRomad, Pozzilli, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.289
    491
    PDF: 0
  • OC02 | INCIDENCE AND PREDICTORS OF ARTERIAL THROMBOSIS IN CANCER PATIENTS: RESULTS FROM THE PROSPECTIVE COMPASS-ARTERIAL CANCER ASSOCIATED THROMBOSIS (COMPASS-ARTECAT) STUDY M. Drakopoulou1, I. Diamandoulaki2, P. Baglaridis1, P. Las Casa3, P. Van Dreden4, K. Toutouzas1, G. Gerotziafas4|5 | 1First Department of Cardiology, School of Medicine, National and Kapodistrian University of Athens, Hippokration General Hospital, Athens, Greece; 2Department of Electrical and Computer Engineering, Aristotle University of Thessaloniki, Thessaloniki, Greece; 3Sorbonne University, INSERM UMR_S_938, CRSA, Research Department "Cancer, Vessels, Biology and Therapeutics" (CaVITE), Research Group "Cancer-Angiogenesis-Thrombosis and Haemostasis," Thrombosis Center, University Institute of Cancerology (UIC), Saint Antoine University Hospital Assistance Publique Hôpitaux de Paris (AP-HP) Paris France; 4Diagnostica Stago, clinical research, Gennevilliers, France; 5Center of Translational Research and Education, Department of Pathology and Laboratory Medicine, Loyola University Stritch School of Medicine, Maywood, Ill., USA

    Società Italiana di Emostasi e Trombosi
    16-04-2026
    https://doi.org/10.4081/btvb.2026.486
    90
    PDF: 21
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Vol. 5 No. 2 (2026)
The small numbers of medicine and the big numbers of artificial intelligence: a curated-data approach to appropriateness in laboratory medicine and...
Anna Mazzetto et al.
15 April 2026
Vol. 5 No. 2 (2026)
Bleeding complications of oral anticoagulant therapy: from ISCOAT to the START Register
Francesco Marongiu
10 April 2026
Vol. 5 No. 2 (2026)
Neurovascular protective effects of nutritional interventions in ischemic brain injury
Geetika Mehta et al.
10 April 2026

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Bleeding, Thrombosis and Vascular Biology

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