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Bleeding, Thrombosis and Vascular Biology

Editor-in-Chief: Giovanni de Gaetano, Italy | eISSN: 2785-5309

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  • The landscape of rare coagulation factor deficiency management in Italy: a national hemophilia center survey

    Silvia Linari, Renato Marino, Marzia Leotta, Antonio Coppola, Patrizia Di Gregorio, Augusto Bramante Federici, Flora Peyvandi, Cristina Santoro, Ezio Zanon, Rita Carlotta Santoro
    05-11-2025
    https://doi.org/10.4081/btvb.2025.369
    1254
    PDF: 187
    HTML: 110
    Appendix: 104
  • Lupus anticoagulant: a never-ending story. New insights from anti prothrombin antibodies

    Vittorio Pengo
    28-08-2026
    https://doi.org/10.4081/btvb.2026.469
    0
    PDF: 0
  • PO12 | IMPACT OF INHERITED THROMBOPHILIA ON CANCER-ASSOCIATED THROMBOSIS: A SYSTEMATIC REVIEW AND META-ANALYSIS E. Campello1, G. Furlan1, A. Boccatonda2, A. Napolitano1, C. Simion1, P. Simioni1 | 1Internal Medicine 1 and Thrombotic and Hemorrhagic Diseases Unit, Department of Medicine, University of Padova, Italy; 2Diagnostic and Therapeutic Interventional Ultrasound Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Policlinico Sant'Orsola-Malpighi, Bologna, Italy

    ICTHIC 2026
    16-04-2026
    https://doi.org/10.4081/btvb.2026.508
    329
    PDF: 80
  • The key to fibrinolysis and thrombolysis

    Roger Lijnen, Désiré Collen
    09-09-2025
    https://doi.org/10.4081/btvb.2025.368
    1623
    PDF: 478
    HTML: 225
  • CO09 | Long term effectiveness and safety of direct oral anticoagulants in patients with factor V Leiden and/or prothrombin gene mutation and venous thromboembolism: a single centre, retrospective cohort study I.M. Palumbo1, E. Valeriani1,2, A. Pannunzio1, S. Marucci3, D. Menichelli1, D. Pastori3,4, P. Pignatelli3 | 1Department of General Surgery and Surgical Specialty, Sapienza University of Roma; 2Department of Infectious Disease, Azienda Ospedaliero-Universitaria Policlinico Umberto I, Roma; 3Department of Clinical Internal, Anaesthesiologic and Cardiovascular Sciences, Sapienza University of Roma; 4IRCCS Neuromed, Pozzilli, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.213
    703
    PDF: 0
  • Diagnostic and management practices for inherited fibrinogen disorders: a nationwide survey of Italian Hemophilia Treatment Centers

    Renato Marino, Silvia Linari, Marzia Leotta, Antonio Coppola, Chiara Biasoli, Maria Elisa Mancuso, Flora Peyvandi, Cristina Santoro, Ezio Zanon, Rita Carlotta Santoro
    02-12-2025
    https://doi.org/10.4081/btvb.2025.372
    802
    PDF: 98
    HTML: 102
    Supplementary: 60
    Appendix: 66
  • CO17 | Clinical relevance of isolated anti-phosphatidylserine/ prothrombin antibody positivity A. Hoxha1, P. Žigon2,3, L. Katja2,3, S. Čučnik2,4, Ž. Rotar2,5, S. Gavasso1, P. Zerbinati1, G. Gobbo1, P. Simioni1 | 1University of Padua, Internal Medicine Unit, Thrombotic and Hemorrhagic Centre, Department of Medicine-DIMED, Padua, Italy; 2University Medical Centre Ljubljana, Department of Rheumatology, Ljubljana, Slovenia; 3University of Primorska, Faculty of Mathematics, Natural Sciences and Information Technologies, Koper, Slovenia; 4University of Ljubljana, Faculty of Pharmacy, Ljubljana, Slovenia; 5University of Ljubljana, Faculty of Medicine, Ljubljana, Slovenia

    22-10-2025
    https://doi.org/10.4081/btvb.2025.221
    590
    PDF: 0
  • PO37 | Single centre experience on anticoagulation in carriers of non-mild inherited thrombophilia: direct oral anticoagulants (DOAC) efficacy and safety M. D’uva1,2, G. La Barba1, G. Montanaro1, M. Di Ianni1,2, P. Ranalli1,2 | 1Hematology Unit, S. Spirito Hospital, Pescara; 2Department of Medicine and Aging Sciences, D’Annunzio University, Chieti, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.300
    603
    PDF: 0
  • PO10 | Clinical and laboratory features of long-Covid syndrome: a cross-sectional study of 1,337 Covid-19 survivors C. Ambaglio1, S. V. Benatti2, C. J. Tartari1,3, L. Russo1,3, S. Bolognini1,3, C. Ticozzi1, F. Schieppati1, V. Brusegan1, S. Venturelli2, L. Barcella1, M. Rizzi2, M. Marchetti1,3, A. Falanga1,3 | 1Department of Immunohematology and Transfusion Medicine, Papa Giovanni XXIII Hospital, Bergamo; 2Division of Infectious Diseases, Papa Giovanni XXIII Hospital, Bergamo; 3Department of Medicine and Surgery, University of Milan Bicocca, Monza, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.272
    592
    PDF: 0
  • PO63 | Atypical venous thrombosis in young patient with systemic lupus erythematosus and high-risk APL profile: provoked or not? E. Marrone, A. Parisi, G. Di Monda, F. Gallucci, D. Morelli, C. Romano, U. Malgeri, D. D’Auria, P. Morella | Internal Medicine Unit 3, Cardarelli Hospital, Naples, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.332
    551
    PDF: 0
  • CO35 | Bleeding phenotype characterization in patients with congenital bleeding disorders: a multigenic approach using next generation sequencing to identify coagulation-modulating variants C. Simion, L. Gianesello, C. Bulato, A. Benetti, E. Campello, A. Giannella, G. Ceolotto, E. Zanon, L. Spiezia, P. Simioni | Department of Medicine – DIMED, University of Padua, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.242
    493
    PDF: 0
  • PO49 | Use of emicizumab in two patients with acquired hemophilia A: a new therapeutic approach S. Sorella, J. Micozzi, E. Baldacci, M. Biglietto, R. Mormile, A. Chistolini, R. Ciciani, L. Torrieri, N. Zhdanovskaya, M. Lorenzon, A. Delli Paoli, S. Ligia, C. Santoro | Hematology, Department of Translational and Precision Medicine, Policlinico Umberto I, Sapienza University of Roma, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.318
    607
    PDF: 0
  • The changing landscape of treatment for acquired hemophilia A

    Massimo Franchini, Daniele Focosi
    30-01-2025
    https://doi.org/10.4081/btvb.2025.157
    1987
    PDF: 522
  • CO32 | Major surgery in patients with severe hemophilia A without inhibitors receiving prophylaxis with fitusiran E. Zanon, C. Simion, A. Napolitano, L. Spiezia, P. Simioni | Haemophilia Center, First Chair of Internal Medicine, Department of Medicine, University-Hospital of Padua Medical School, Padua, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.239
    508
    PDF: 0
  • PO45 | Routine prophylaxis with PD-FX concentrate in severe inherited FX deficiency: a case report S. Linari, L. Pieri, M. Attanasio, F. Salvianti, M. Coppo, E. Grisanti, F. Demartis, R. Fjerza, G. Castaman | Centre for Bleeding Disorders and Coagulation, Azienda Ospedaliera Universitaria Careggi, Firenze, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.308
    559
    PDF: 0
  • Influence of emicizumab on protein C-mediated clotting regulation

    Federica Mancazzo, Antonia Vitulli, Lavinia Dirienzo, Concetta T. Ammollo, Fabrizio Semeraro, Mario Colucci
    25-10-2023
    https://doi.org/10.4081/btvb.2023.89
    2607
    PDF: 407
    Supplementary Material: 121
  • CO19 | Hypercoagulability in wild-type transthyretin amyloidosis: evidence from whole blood thromboelastometry A. Napolitano1, L. Spiezia1, C. Samà1, A. Benetti1, G. Sinigiani2, L. De Michieli2, A. Cipriani2, P. Simioni1 | 1First Chair of Internal Medicine, Department of Medicine, University Hospital of Padua; 2Department of Cardiothoracic and Vascular Sciences & Public Health, University Hospital of Padua, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.223
    540
    PDF: 0
  • PO44 | Emicizumab in acquired haemophilia A M. Leotta, A. Strangio, A. Ierardi, S. Prejanò, R C. Santoro | Hemostasis and Thrombosis Unit, Department Hemato-Oncology, Azienda Ospedaliero-Universitaria Renato; Dulbecco, Catanzaro, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.307
    575
    PDF: 0
  • A case of acquired factor XIII deficiency secondary to plasmablastic lymphoma

    Vincenzo Sammartano, Adele Santoni, Elisabetta Zappone, Paola Calzoni, Daniela Fineschi, Eleonora Franceschini, Federico Caroni, Anna Sicuranza, Monica Bocchia, Luca Puccetti
    09-03-2023
    https://doi.org/10.4081/btvb.2023.53
    1362
    PDF: 530
  • Expanding the genetic landscape of hereditary thrombophilia: classical defects, novel variants, and genomic perspectives. A narrative review

    Chiara Simion, Elena Campello, Walter Ageno, Paolo Simioni
    28-08-2026
    https://doi.org/10.4081/btvb.2026.427
    0
    PDF: 0
    SUPPLEMENTARY FILES: 0
  • Safety of COVID-19 mRNA vaccination in patients with history of acquired hemophilia A: a case series

    Luca Puccetti, Vincenzo Sammartano, Federico Caroni, Margherita Malchiodi, Paola Calzoni, Eleonora Franceschini, Lucrezia Galasso, Monica Bocchia
    17-10-2022
    https://doi.org/10.4081/btvb.2022.40
    3003
    PDF: 398
  • PO77 | The clinical awareness of mixing test interpretation in the era of complex reporting algorithm: do we forget the origins? A. Fassina, L. De Valentin, S. Luzi, R. Turrini, A. Antico, L. Zardo | Laboratorio Analisi Castelfranco Veneto, ULSS Marca Trevigiana, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.346
    582
    PDF: 0
  • CO16 | The predictive value of high-sensitivity C-reactive protein for assessing thrombosis risk in non-small cell lung cancer P. Gomez-Rosas1,2, M. Marchetti1,3, L. Russo1, C.J. Tartari1, S. Bolognini1, C. Ticozzi1, F. Schieppati1, A. D’Alessio4, R. Labianca5, A. Falanga1,3 All on behalf of the Hypercan Investigators | 1Hospital Papa Giovanni XXIII, Bergamo, Italy; 2Cardiovascular Research Institute Maastricht, CARIM, Maastricht University, Maastricht, the Netherlands; 3School of Medicine and Surgery, University of Milan Bicocca, Italy; 4University Vita-Salute San Raffaele, Milan, Italy; 5Fondazione ARTET Onlus, Bergamo, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.220
    585
    PDF: 0
  • PO27 | B-cell lymphoproliferative disorder and acquired coagulopathy: an insidious link C. Caputo, P. Conca, I.L. Calcaterra, E. Cimino, M. Romeo, M. Aversano, E. Franco, C. De Luca, R. Russo, C. Fierarossa, M.N.D. Di Minno, A. Tufano | Department of Clinical Medicine and Surgery, Federico II University, Naples, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.288
    571
    PDF: 0
  • Evaluation of Coaguchek® Pro II coagulation testing device performance to assess direct oral anticoagulant action. The DOAC-CHECK study

    Cristina Legnani, Michela Cini, Sophie Testa, Alberto Tosetto, Claudia Dellanoce, Stefania Bellesso, Giuseppe Carli, Ilaria Nichele, Laura Lissandrini, Serena Zorzi, Emilia Antonucci, Gualtiero Palareti
    01-12-2022
    https://doi.org/10.4081/btvb.2022.37
    2172
    PDF: 436
  • PO66 | Viscoelastic tests in disseminated intravascular coagulation associated with aortic aneurysm A. M. Pizzini1, C. Biasoli2, M. Bovara3, E. Gesuete1, A. Fusco1, C. Fantoni1, P. Pedrazzi2, R. Mancini3, M. Silingardi1 | 1Ambulatorio Emostasi & Trombosi, Dipartimento Medico, Ospedale Maggiore AUSL Bologna; 2SSI Presa in Carico delle Malattie Emorragiche e Tromboemboliche della Romagna; 3Laboratorio Unico Metropolitano AUSL Bologna, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.335
    586
    PDF: 0
  • CO11 | Oral anticoagulation with vitamin K antagonists in early childhood: a single centre-experience B. Borsellino1,2, B. Pollio1, I. Ricca1, R. Albiani1, T. Martini1 | 1Haemophilia Centre, Immune-Haematology and Transfusion Medicine, University Hospital “Città della Salute e della Scienza”, Torino; 2Department of Biomedicine and Prevention, PhD in Immunology, Molecular Medicine and Applied Biotechnology, University of Roma Tor Vergata, Roma, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.215
    653
    PDF: 0
  • PO42 | DIFFERENTIAL EXPRESSION OF HEMOSTATIC BIOMARKERS ACROSS CANCER TYPE AND DISEASE STAGE: A PROSPECTIVE ANALYSIS OF 4,292 PATIENTS FROM THE HYPERCAN STUDY P. Gómez-Rosas1|2|, D. Romeo1, S. Bolognini1, C. Ticozzi1, F. Schieppati1, A. D’Alessio4, R. Labianca4, A. Falanga1|5|6, M. Marchetti1|5|6 | 1Hospital Papa Giovanni XXIII, Bergamo, Italy; 2Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, the Netherlands; 3Hospital de Oncologia, Unidad Medica de Alta Especialidad (UMAE), Centro Medico Nacional Siglo XXI, Instituto Mexicano del Seguro Social (IMSS), Mexico City, Mexico; 4Fondazione ARTET Onlus, Bergamo, Italy; 5ERN EuroBloodNet; 6School of Medicine and Surgery, University of Milan Bicocca, Italy; *On Behalf Of The Hypercan Investigators

    ICTHIC 2026
    16-04-2026
    https://doi.org/10.4081/btvb.2026.536
    337
    PDF: 96
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Bleeding, Thrombosis and Vascular Biology

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