Thrombophilia work-up and clinical outcomes in Indian patients with unprovoked venous and arterial thrombosis aged 18-50 years | BTVB Bioequivalence of von Willebrand factor-containing concentrates: implications for von Willebrand disease | BTVB Cardiovascular risk in hormone replacement therapy | BTVB Direct oral anticoagulants: does one dose fit all? Why, when and how testing | BTVB Cardiovascular risk profile evolution over 15 years: CV-PREVITAL vs Moli-sani Study | BTVB Launch of National Registry for Congenital Hematological Disorders in Palestine: Haemo-PAL | BTVB
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Bleeding, Thrombosis and Vascular Biology

Editor-in-Chief: Giovanni de Gaetano, Italy | eISSN: 2785-5309

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  • A commitment to global collaboration, welcoming international participation and advancing science for the benefit of patients

    Pantep Angchaisuksiri, Wolfram Ruf, Jeffrey Weitz, Sam Schulman, Guy A. Young
    01-07-2025
    https://doi.org/10.4081/btvb.2025.188
    1632
    PDF: 331
    HTML: 126
  • PO59 | Efficacy and safety of different anticoagulant treatment regimens for isolated internal jugular vein thrombosis: a case series A. Pannunzio1, E. Valeriani1, I.M. Palumbo1, S. Marucci2, D. Menichelli1, D. Pastori2, P. Pignatelli2 | 1Department of General Surgery and Surgical Specialty, Sapienza University of Roma; 2Department of Clinical, Internal Medicine, Anaesthesiological and Cardiovascular Sciences, Sapienza University of Roma, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.328
    684
    PDF: 27
  • BEST-07 | ULTRASOUND EVALUATION AND JOINT SCORING IN MILD HEMOPHILIA A: A SINGLE-CENTER CASE SERIES FOR THE IDENTIFICATION OF SUBCLINICAL ARTHROPATHY M. Leotta, A. Strangio, R.C. Santoro | Hemophilia Hemostasis and Thrombosis Unit, Azienda Ospedaliero Universitaria Renato Dulbecco, Catanzaro, Italy

    Marzia Leotta
    14-10-2026
    https://doi.org/10.4081/btvb.2026.607
    13
    PDF: 3
  • A case of thrombotic thrombocytopenic purpura presented in a popular TV series

    Raffaele Landolfi
    01-07-2025
    https://doi.org/10.4081/btvb.2025.181
    1127
    PDF: 743
  • PO41 | Comparison of the haemorrhagic phenotype between female and male patients affected by autosomal inherited bleeding disorders in a single-centre cohort B. Borsellino1,3, C. Zuccotti2, L. Guarnera3,4, C. Biasoli5, P. Pedrazzi5, T. Martini1 | 1Haemophilia Centre, Immune-Haematology and Transfusion Medicine, University Hospital “Città della Salute e della Scienza”, Turin, Italy; 2Department of Clinical Pathology, Bufalini Hospital, Cesena, Italy; 3Department of Biomedicine and Prevention, PhD in Immunology, Molecular Medicine and Applied Biotechnology, University of Roma Tor Vergata, Roma, Italy; 4Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH, USA; 5Haemophilia and Transfusion Centre, Bufalini Hospital, Cesena, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.304
    603
    PDF: 19
  • Persistence of functional anti-PF4 antibodies and neutrophil activation in vaccine-induced immune thrombotic thrombocytopenia

    Eleonora Petito, Anna Maria Mezzasoma, Emanuela Falcinelli, Chiara Conti, Erica De Candia, Raimondo De Cristofaro, Silvia Sorrentino, Gian Marco Podda, Mariangela Scavone, Anna Falanga, Marina Marchetti, Luca Barcella, Stefania Basili, Lucia Stefanini, Andrea Boccatonda, Laura Contino, Patrizia Sciancalepore, Igor Florio, Egidio Imbalzano, Rossella Marcucci, Angela Rogolino, Patrizia Noris, Marta Panella, Rita Santoro, Maria Costanza Turi, Gaetano Vaudo, Rosa Curcio, Paolo Gresele
    18-11-2025
    https://doi.org/10.4081/btvb.2025.400
    944
    PDF: 167
    HTML: 201
  • PO54 | Resolvin response in bronchial asthma patients: endotype and clinical severity R. Liani1, I. Altomare2, P.G.M. Simeone1, M. Alfonsetti1, M. Mucci3, D. Madonna1, S. Lattanzio1, A. Ricci4, A.M. Draicchio2, A. De Sanctis2, P. Di Mattia2, F. Papa2, E. Cavallucci2, F. Cipollone1, A. Recchiuti3, F. Santilli1 | 1Department of Medicine and Aging, and Center for Advanced Studies and Technology “CAST”, G. d’Annunzio University of Chieti-Pescara, Chieti; 2Allergy and Immunology Section, Department Internal Medicine, G. d’Annunzio University, School of Medicine, Chieti; 3Department of Medical, Oral and Biotechnological Sciences, and Center for Advanced Studies and Technology “CAST”, G. d’Annunzio University, Chieti-Pescara; 4Department of Pharmacy, University G. d’Annunzio of Chieti Pescara, Chieti, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.323
    574
    PDF: 14
  • Bleeding and thrombosis in patients receiving chimeric antigen receptor T-cell therapy

    Dana Lee, Pedro Luiz Lage Bodour Danielian, Avi Leader
    16-04-2026
    https://doi.org/10.4081/btvb.2026.461
    332
    PDF: 173
  • BEST-06 | OPTIMIZING LABORATORY MONITORING OF EFANESOCTOCOG ALFA: IMPACT OF APTT REAGENTS AND CHROMOGENIC ASSAYS ON DIAGNOSTIC ACCURACY A. Strangio, A. Ierardi, M. Leotta, L.C. Elia, M. Falbo, C. Condina, G. Procopio, R.C. Santoro | Hemophilia Hemostasis and Thrombosis Unit, Azienda Ospedaliero Universitaria Renato Dulbecco, Catanzaro, Italy

    Alessandra Strangio
    14-10-2026
    https://doi.org/10.4081/btvb.2026.606
    14
    PDF: 3
  • PO49 | Use of emicizumab in two patients with acquired hemophilia A: a new therapeutic approach S. Sorella, J. Micozzi, E. Baldacci, M. Biglietto, R. Mormile, A. Chistolini, R. Ciciani, L. Torrieri, N. Zhdanovskaya, M. Lorenzon, A. Delli Paoli, S. Ligia, C. Santoro | Hematology, Department of Translational and Precision Medicine, Policlinico Umberto I, Sapienza University of Roma, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.318
    653
    PDF: 21
  • Preface to the 13th International Conference on Thrombosis and Hemostasis Issues in Cancer, 2026

    Anna Falanga, Benjamin Brenner, Alok A. Khorana
    16-04-2026
    https://doi.org/10.4081/btvb.2026.479
    508
    PDF: 222
  • BEST-04 | MAJOR ORTHOPEDIC SURGERY WITH EMICIZUMAB: A SERIES OF 22 PATIENTS (40 PROCEDURES) WITH A MID-TERM FOLLOW-UP G. Daniele1, C. Carulli1, S. Linari2, L. Pieri2, G. Castaman2 | 1Clinica Ortopedica, Azienda Ospedaliero-Universitaria Careggi, Università degli Studi di Firenze, Italy; 2Centro Malattie Emorragiche e della Coagulazione, Azienda Ospedaliero-Universitaria Careggi, Firenze, Italy

    Giovanna Daniele
    14-10-2026
    https://doi.org/10.4081/btvb.2026.604
    16
    PDF: 2
  • Cancer-associated thrombosis: limitations of conventional models and advances with endothelial cell-based microfluidics incorporating thrombin generation

    Dongyue Fan, Araci M.R. Rondon, Henri H. Versteeg
    16-04-2026
    https://doi.org/10.4081/btvb.2026.438
    555
    PDF: 138
  • The use of creatine and the development of deep vein thrombosis. A scoping review

    Kartik Akkihal, Thomas Varkey, James Kelbert
    18-11-2024
    https://doi.org/10.4081/btvb.2024.142
    9033
    PDF: 799
    Supplementary: 210
  • Why medical fiction privileges certain disease manifestations

    Raffaele Landolfi
    15-05-2026
    https://doi.org/10.4081/btvb.2026.562
    1066
    PDF: 148
  • PO12 | Characterisation and real word clinical data of HEM006, a newly formulated intranasal spray desmopressin (DDAVP) to address a global treatment gap G. De Giorgi1, A. Gringeri2, R. Franceschini1, A. Koganti3 | 1Hemorare Srl, Italy; 2Fondazione Charta, Milan, Italy; 3Quenya LLC, USA

    22-10-2025
    https://doi.org/10.4081/btvb.2025.274
    564
    PDF: 12
  • Anticoagulant treatment in patients with internal jugular vein thrombosis: a case serie

    Arianna Pannunzio, Ilaria Maria Palumbo, Luca Tretola, Elena Ciambella, Valentina Castellani, Maddalena Ragazzo, Pasquale Pignatelli, Emanuele Valeriani
    14-10-2026
    https://doi.org/10.4081/btvb.2026.422
    40
    PDF: 12
  • Thrombotic thrombocytopenic purpura: much done, but still a lot to do

    Paola Binetti
    29-08-2024
    https://doi.org/10.4081/btvb.2024.149
    968
    PDF: 394
  • PO38 | PERICATHETER AND SYSTEMIC THROMBOSIS DURING CAR-T LYMPHOCYTAPHERESIS: INCIDENCE AND CLINICAL CORRELATES I. Pansini1|2, E. Galli1, A. Corrente2, N. Piccirillo1|2, M. Viscovo1|2, S. Hohaus1|2, P. Chiusolo1|2, F. Sorà1|2, S. Sica1|2 | 1Department of Laboratory and Hematologic Sciences, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome; 2Hematology Section, Department of Radiologic and Hematologic Sciences, Università Cattolica del Sacro Cuore, Rome, Italy

    ICTHIC 2026
    16-04-2026
    https://doi.org/10.4081/btvb.2026.532
    418
    PDF: 99
  • CO48 | Gynecological involvement in females with congenital plasminogen deficiency type 1 C. Dalla Porta1,2, M.T. Sartori1, G. Saggiorato1, I. Cortella1, S.A. Malerba1,3, P. Simioni1 | 1First Medical Clinic, Department of Medicine - DIMED, Università degli Studi di Padova; 2Department of Medicine, Casa di Cura Villa Maria, Padova; 3Medicina Generale, Ospedale dell’Angelo, Mestre, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.258
    554
    PDF: 16
  • CO-66 | PREGNANCY OUTCOMES AND PERIPARTUM MANAGEMENT IN WOMEN WITH CONGENITAL FIBRINOGEN DISORDERS: A SINGLE-CENTRE EXPERIENCE T. Martini1, B. Borsellino1|2, B. Pollio1 | 1Haemophilia Centre, Immune-Haematology and Transfusion Medicine, University Hospital “Città della Salute e della Scienza”, Torino, Italy; 2Department of Biomedicine and Prevention, PhD in Immunology, Molecular Medicine and Applied Biotechnology, University of Rome Tor Vergata, Roma, Italy

    Tiziano Martini
    14-10-2026
    https://doi.org/10.4081/btvb.2026.676
    16
    PDF: 2
  • PO81 | Direct oral anticoagulants in atypical site vein thrombosis: a single centre experience focused on cancer patients U. Mazzarelli1, A. Guida1, L. Agrelli1, M. Amato1, R. Guarrasi2, L. Santaniello2, C. Cardamone1, P. Vitale1, M. Triggiani1 | 1Centro per le Malattie Emorragiche Congenite e Malattie Trombotiche UOC Clinica Immunologica e Reumatologica AOU S. Giovanni di Dio e Ruggi d’Aragona, Salerno; 2UOC Clinica Oncologica AOU S. Giovanni di Dio e Ruggi d’Aragona, Salerno, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.350
    628
    PDF: 19
  • Safety of COVID-19 mRNA vaccination in patients with history of acquired hemophilia A: a case series

    Luca Puccetti, Vincenzo Sammartano, Federico Caroni, Margherita Malchiodi, Paola Calzoni, Eleonora Franceschini, Lucrezia Galasso, Monica Bocchia
    17-10-2022
    https://doi.org/10.4081/btvb.2022.40
    3046
    PDF: 428
  • PO05 | DESIGN, SYNTHESIS, AND BIOLOGICAL EVALUATION OF NOVEL IMATINIB AND NILOTINIB ANALOGUES EXPRESSING ENHANCED ANTIPLATELET AND ANTICANCER ACTIVITIES D. Pantazi1, L. Pechlivani1, A. Kosma1, K. Lalechou1, M.G. Siskos2, D. Alivertis3, A.D. Tselepis1 | 1Atherothrombosis Research Centre, Laboratory of Biochemistry, Department of Chemistry, University of Ioannina, Greece; 2Laboratory of Organic Chemistry, Department of Chemistry, University of Ioannina, Greece; 3Department of Biological Applications and Technology, University of Ioannina, Greece

    ICTHIC 2026
    16-04-2026
    https://doi.org/10.4081/btvb.2026.501
    529
    PDF: 98
  • CO07 | Real word management of anticoagulant therapy in brain metastasis: moving toward a multidisciplinary approach in complex cases E. Lotti1, C. Manneschi2, S. Fancelli2, F. Scolari1, F. Crudele1, D. Poli1, M. Berteotti1, D. Rossini3, S. Pillozzi2, L. Antonuzzo2,3, R. Marcucci1,3 | 1Disease Unit, Careggi University Hospital, Firenze; 2Oncology Unit, Careggi University Hospital, Firenze; <sup>3</sup>Department of Experimental and Clinical Biomedical Sciences, University of Firenze, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.211
    615
    PDF: 20
  • CO-40 | ONE-STAGE ASSAYS VS. CHROMOGENIC ASSAYS IN rpFVIII: STILL A DISCREPANCY? L. Banov, G. Gazzelli, Y. Azzanelli, C. Vernarecci, F. Marotta, F. Giacopelli, F. Tappino, A.C. Molinari | IRCCS Istituto Giannina Gaslini, Genova, Italy

    Angelo Claudio Molinari
    14-10-2026
    https://doi.org/10.4081/btvb.2026.650
    15
    PDF: 2
  • OC10 | FROM DESIGN TO CLINICAL PHASE 3 IN ONCOLOGY: CD13-TARGETED TISSUE FACTOR AND TUMOR INFARCTION W.E. Berdel, C. Schwöppe, C. Brand, K. Hessling, A.F. Berdel, T. Kessler, G. Lenz, R.M. Mesters, C. Schliemann | Department of Medicine A, University Hospital, Muenster, Germany

    ICTHIC 2026
    16-04-2026
    https://doi.org/10.4081/btvb.2026.493
    454
    PDF: 93
  • The importance of rigorous and engaging scientific communication

    Giovanni de Gaetano
    01-07-2025
    https://doi.org/10.4081/btvb.2025.191
    1529
    PDF: 356
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Vol. 5 No. 4 (2026)
Platelets versus monocytes as cellular sources of blood-borne tissue factor: a quantitative and functional comparison in healthy subjects...
Marina Camera et al.
12 October 2026
Vol. 5 No. 4 (2026)
Von Willebrand Disease (VWD) 100 years after its first description: the research of Italian investigators for a better management of VWD patients
Augusto B. Federici et al.
9 October 2026
Vol. 5 No. 4 (2026)
The history of the TIMI, GISSI, and ISIS trials: the development of thrombolytic therapy in acute myocardial infarction
Aldo Pietro Maggioni et al.
13 October 2026
Vol. 5 No. 4 (2026)
Anticoagulant treatment in patients with internal jugular vein thrombosis: a case serie
Arianna Pannunzio et al.
14 October 2026

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Bleeding, Thrombosis and Vascular Biology

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