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PO46 | Intravitreal treatment with faricimab in patients with age-related macular degeneration M. Alfonsetti1, R. Liani1, P.G.M. Simeone1, M. Frezza1, A. Ricci3, S. Lattanzio1, R. D’Aloisio2, L. Toto2, F. Santilli1 | 1Department of Medicine and Aging, Center for Advanced Studies and Technology “CAST”; 2Ophthalmology Clinic, Department of Medicine and Aging; 3Department of Pharmacy, University “G. d’Annunzio” of Chieti Pescara, Chieti, Italy
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PO54 | Resolvin response in bronchial asthma patients: endotype and clinical severity R. Liani1, I. Altomare2, P.G.M. Simeone1, M. Alfonsetti1, M. Mucci3, D. Madonna1, S. Lattanzio1, A. Ricci4, A.M. Draicchio2, A. De Sanctis2, P. Di Mattia2, F. Papa2, E. Cavallucci2, F. Cipollone1, A. Recchiuti3, F. Santilli1 | 1Department of Medicine and Aging, and Center for Advanced Studies and Technology “CAST”, G. d’Annunzio University of Chieti-Pescara, Chieti; 2Allergy and Immunology Section, Department Internal Medicine, G. d’Annunzio University, School of Medicine, Chieti; 3Department of Medical, Oral and Biotechnological Sciences, and Center for Advanced Studies and Technology “CAST”, G. d’Annunzio University, Chieti-Pescara; 4Department of Pharmacy, University G. d’Annunzio of Chieti Pescara, Chieti, Italy
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PO88 | Bacterial lysate “lantigen B” induces proliferation of B and NK cells and the release of related cytokines M. Alfonsetti1, R. Liani1, P. Di Mattia3, M. Tredicine4, F. Papa3, Q. Niu5, M. Di Gioacchino2, F. Santilli1,3 | 1Department of Medicine and Aging, Center for Advanced Studies and Technology, University of Chieti, Italy; 2Institute for Clinical Immunotherapy and Advanced Biological Treatments, Pescara, Italy; 3Specialization School of Allergy and Clinical Immunology, G. d’Annunzio University, Chieti, Italy; 4Department of Medical, Oral, and Biotechnology Science, University G. d’Annunzio, Chieti-Pescara, Chieti, Italy; 5Department of Occupational Health, School of Public Health, Shanxi Medical University, Taiyuan, Shanxi, China
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CO25 | Thromboinflammation and ros accumulation in individuals with high lipoprotein(a) levels M. Frezza1, P.G.M. Simeone1, M. Alfonsetti1, R. Liani1, M. Cellini1, P. Del Boccio2, M.C. Cufaro3, O. Iuliani4, A. Quaglietta4, F. Cipollone1, F. Santilli1 | 1Department of Medicine and Ageing Sciences, Center for Advanced Studies and Technology “CAST”, University of Chieti; 2Department of Pharmacy, Center for Advanced Studies and Technology “CAST”, Chieti; 3Department of Innovative Technologies in Medicine and Dentistry, Center for Advanced Studies and Technology “CAST”, Chieti; 4Department of Haematolgy and Oncology, Center of Transfusion Medicine, Pescara General Hospital, Pescara. Italy
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CO42 | Oxidative stress may contribute to enhanced thrombopoiesis through miR-150: implications for aspirin response R. Liani1, P.G.M. Simeone1, M. Alfonsetti1, M. Frezza1, R. Tripaldi1, S. Ciotti1, M. Luongo2, F. Cipollone1, L. Vanella3, F. Santilli1 | 1Department of Medicine and Aging, and Center for Advanced Studies and Technology “CAST”, G. d’Annunzio University of Chieti-Pescara, Chieti; 2Immunotransfusion Service, Clinical Haematology of Chieti University Hospital, Chieti; 3Department of Drug Sciences, University of Catania, Italy
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CO45 | Role of urinary 11-dehydro-thromboxane B2 as a predictor of preeclampsia in pregnant high-risk women on low-dose aspirin treatment P.G.M. Simeone1, R. Liani1, M. Alfonsetti1, A. Ricci1, V. Cianci1, S. Zeeba2, M. Molino3, S. Palma2, R. Malizia4, M. Luongo4, A. Di Castelnuovo5, F. Cipollone1, F. D’antonio6, F. Ricci2, G. Renda2, F. Santilli1 | 1Department of Medicine and Aging Sciences, Center for Advanced Studies and Technology, University of Chieti; 2Department of Neuroscience, Imaging and Clinical Sciences, G D’Annunzio University of Chieti-Pescara, Chieti; University Cardiology Division, Heart Department, Policlinico SS Annunziata, Chieti; 3Clinical Pathology of Chieti University Hospital; 4Immunotransfusion Service, Clinical Haematology of Chieti University Hospital, Chieti; 5Mediterranea Cardiocentro, Napoli; 6Centre for Fetal Care and High-Risk Pregnancy, Department of Obstetrics and Gynecology, University of Chieti, Italy
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PO32 | Effect of the sodium-glucose co-transporter-2 (SGLT2) inhibitors on platelet activation and lipid peroxidation: results of a pilot study P.G.M. Simeone1, R. Liani1, M. Alfonsetti1, B. Cancelli1, M. Frezza1, G. Raggiunti1, S. Zeeba2, F. Cipollone1, G. Renda2, F. Santilli1 | 1Department of Medicine and Aging Sciences, Center for Advanced Studies and Technology, University of Chieti; 2Department of Neuroscience, Imaging and Clinical Sciences, G. D’Annunzio University of Chieti-Pescara; 3University Cardiology Division, Heart Department, Policlinico SS Annunziata, Chieti, Italy
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