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• PO93 | Use of DOACS in heart transplantation recipients T. Marrazzo¹, A. Delle Femine¹, C. Amarelli², R. Albisinni³ | ¹UOC Medicina Interna e dei Trapianti, Ospedale Monaldi Azienda dei Colli, Napoli; ²UOSD CCH dei Trapianti, Ospedale Monaldi Azienda dei Colli, Napoli; ³UOC CCH Generale, Ospedale Monaldi Azienda dei Colli, Napoli, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.363

  384

  PDF: 0

• CO21 | Viscoelastic testing in inherited bleeding disorders: a cross-sectional comparison between viscoelastic coagulation monitoring and rotational thromboelastometry C. Simion, C. Samà, C. Bulato, G. Gottardi, D. Regazzo, E. Campello, P. Simioni | Department of Medicine – DIMED, University of Padua, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.227

  325

  PDF: 0

• PO22 | Early detection and management of PICC-related thrombosis in oncohematologic patients through serial ultrasound monitoring: a prospective observational study S. Laurenti, M. Schneeberger, G. Rosati, A. Pozzi, M. Padrini, R. Vacchelli, A. Morotti | University of Turin, AUO San Luigi Gonzaga, Orbassano (TO), Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.282

  318

  PDF: 0

• PO13 | Monitoring of anti-factor XA activity levels in patients treated with direct oral anticoagulants and concomitant tyrosine kinase inhibitors agents: a monocentric experience E. Santacroce^1,2, C. Santoro¹, E. Baldacci¹, S. Ligia¹, R. Mormile¹, M. Biglietto¹, M. Totaro¹, F. R. Mauro¹, M. Breccia¹, A. Chistolini¹ | ¹Department of Translational and Precision Medicine, Haematology, Sapienza University of Roma; ²Department of Clinical and Molecular Medicine, Sapienza University of Roma, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.313

  311

  PDF: 0

• CO22 | Assessment of coagulation profiles in septic patients using viscoelastic coagulation monitoring and rotational thromboelastometry in an internal medicine setting G. Gottardi, C. Simion, D. Regazzo, C. Samà, G.P. Arcidiacono, L. Gianesello, E. Campello, P. Simioni | Department of Medicine – DIMED, University of Padua, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.228

  320

  PDF: 0

• PO90 | Acquired hemophilia A with high-titer inhibitor in a patient with cardiovascular and metabolic comorbidities M.G. Mazzone, G. Chiarelli, R. Russo, L. Valletta Jr, G. D’Errico, C. De Luca, P. Rufolo, A. Tufano, E. Cimino, P. Conca, M.N.D. Di Minno | Department of Clinical Medicine and Surgery, Federico II University of Naples, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.360

  362

  PDF: 0

• PO89 | Apixaban for secondary prevention of venous thromboembolism in hemodialysis patients: pharmacokinetic profile and safety outcomes S. Guglielmo¹, E. De Bon², L. Scarano¹, R. Fabris¹, E. Pierobon³, S. Barbar² | ¹Internal Medicine, Department of Medicine; ²Thrombotic and Hemorrhagic Disorders Unit, Department of Medicine; ³Nephrology and Dialysis Unit, Azienda ULSS 6 Euganea, Cittadella and Camposampiero, Padua, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.359

  379

  PDF: 0

• PO31 | Comparative analysis of anticoagulant therapy in patients over 90 years old: vitamin K antagonists versus direct oral anticoagulants G. Sottilotta¹, P. Arrigo², S. Cuzzocrea¹, D. Megalizzi¹, F. Luise³ | ¹UOSD Microcitemie, Emostasi e Trombosi, Grande Ospedale Metropolitano di Reggio Calabria; ²Associazione Italiana Pazienti Anticoagulati, Sezione di Reggio Calabria; ³Laboratorio Analisi. Grande Ospedale Metropolitano di Reggio Calabria, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.292

  305

  PDF: 0

• CO15 | Longitudinal coagulation profiling of individuals undergoing gender-affirming hormone therapy: the hyper-gender study A. Napolitano, E. Campello, A. Scala, C. Simion, C. Bulato, S. Gavasso, C. Samà, A. Benetti, S. Toffanin, G. Faggian, R. Scafa, A. Garolla, P. Simioni | First Chair of Internal Medicine, Department of Medicine, University Hospital of Padua; Unit of Andrology and Reproductive Medicine, Department of Medicine, University Hospital of Padua, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.219

  309

  PDF: 0

• PO79 | Trying to hit the hit in the shadow of renal failure: a complex case managed with danaparoid S. Chessa^1,2, M. Anedda², M.V. Cherchi², M. Vacca^1,2, M. Caboni², J. Pilia², A.M. Bussu², M. Mantega², G. Costanzo¹, D. Firinu¹, S. Del Giacco¹, A. Mameli³, D. Barcellona³ | ¹Department of Medical Science and Public Health, University of Cagliari; ²Internal Medicine, ASL Sulcis, PO Sirai, Carbonia; ³Department of Medical Sciences and Public Health, Hemostasis and Thrombosis Unit, University of Cagliari and AOU of Cagliari, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.348

  338

  PDF: 0

• CO36 | Inhibitor titer at diagnosis and clinical course in acquired hemophilia A: a single-center experience C. Simion, B. Stocco, E. Dalla Porta, E. Campello, G. Furlan, L. Spiezia, G. Saggiorato, F. Sartorello, E. Zanon, P. Simioni | Department of Medicine – DIMED, University of Padua, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.243

  255

  PDF: 0

• PO30 | Acquired angioedema associated with B-non Hodgkin lymphoma: a case report A. Pozzi, G. Rosati, S. Pizzimenti, M. Padrini, S. Laurenti, G. Ferrari, R. M. Medici, C. Barale, I. Russo, A. Morotti | Univeristy of Turin, AUO San Luigi Gonzaga, Orbassano (TO), Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.291

  278

  PDF: 0

• CO11 | Oral anticoagulation with vitamin K antagonists in early childhood: a single centre-experience B. Borsellino^1,2, B. Pollio¹, I. Ricca¹, R. Albiani¹, T. Martini¹ | ¹Haemophilia Centre, Immune-Haematology and Transfusion Medicine, University Hospital “Città della Salute e della Scienza”, Torino; ²Department of Biomedicine and Prevention, PhD in Immunology, Molecular Medicine and Applied Biotechnology, University of Roma Tor Vergata, Roma, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.215

  347

  PDF: 0

• PO70 | Clinical safety and monitoring of apixaban combined with tacrolimus and everolimus in kidney transplant patients: a prospective study S. Guglielmo¹, E. De Bon², L. Scarano¹, R. Fabris¹, E. Pierobon³, S. Barbar² | ¹Internal Medicine, Department of Medicine, Azienda ULSS 6 Euganea, Cittadella; ²Thrombotic and Hemorrhagic Disorders Unit, Department of Medicine, Azienda ULSS 6 Euganea, Cittadella; ³Nephrology and Dialysis Unit, Azienda ULSS 6 Euganea, Cittadella and Camposampiero, Padova, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.339

  319

  PDF: 0

• CO32 | Major surgery in patients with severe hemophilia A without inhibitors receiving prophylaxis with fitusiran E. Zanon, C. Simion, A. Napolitano, L. Spiezia, P. Simioni | Haemophilia Center, First Chair of Internal Medicine, Department of Medicine, University-Hospital of Padua Medical School, Padua, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.239

  295

  PDF: 0

• PO25 | Baseline thrombin generation test does not predict thrombotic events in acute leukemia: a monocentric prospective study M. Biglietto, R. Mormile, M.L. Bisegna, A. Laganà, A. L. Faccini, A. Papa, E. Baldacci, C. Santoro, M.S. De Propris, A. Chistolini | Hematology, Department of Translational and Precision Medicine Sapienza University of Roma, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.286

  310

  PDF: 0

• CO08 | The utility of urine qualitative assessment for direct oral anticoagulants in routine clinical practice F. Schieppati^1,2, P. Gomez-Rosas^1,3, C. Ambaglio¹, V. Brusegan¹, Oc. Cretu^1,2, E. Galimberti¹, F. Zunino¹, L. Barcella¹, J. Harenberg^4,5, A. Falanga^1,2, M. Marchetti^1,2 | ¹Immunohematology and Transfusion Medicine, Hospital Papa Giovanni XXIII, Bergamo, Italy; ²School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy; ³Maastricht University Medical Center, Cardiovascular Research Institute Maastricht, Maastricht, The Netherlands; ⁴Ruprecht Karls University of Heidelberg, Germany; ⁵Germany DOASENSE GmbH, Heidelberg, Germany

  22-10-2025

  https://doi.org/10.4081/btvb.2025.212

  364

  PDF: 0

• PO53 | Effectiveness and safety of DOACS in patients with renal transplantation A. Ierardi, A. Strangio, M. Leotta, R C. Santoro | UO Emofilia, Emostasi e Trombosi, AOU Renato Dulbecco, Catanzaro, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.322

  321

  PDF: 0

• CO28 | Cognitive, adaptive abilities and behavioral symptoms in children and adolescents with hemophilia: a pilot study R. Vallone¹, M. Luciani², A. Smigliani², M. F. Mansueto³, S. Vicari^1,4, D. Menghini¹ | ¹Child and Adolescent Neuropsychiatry Unit, Bambino Gesù Children’s Hospital, IRCCS, Roma; ²OncoHematology Unit, Bambino Gesù Children’s Hospital, IRCCS, Roma; ³Department of Oncology U.O. Hematology AUO Policlinico, Paolo Giaccone, Palermo; ⁴Department of Life Science and Public Health, Università Cattolica del Sacro Cuore, Roma, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.234

  317

  PDF: 0

• CS05 | Joint ultrasound follow-up in pediatric patients with haemophilia: a 12-year prospective single-center experience B. Borsellino^1,2, B. Pollio¹, C. Martinoli³, T. Martini¹, R. Albiani¹, I. Ricca¹ | ¹Haemophilia Centre, Immune-Haematology and Transfusion Medicine, University Hospital “Città della Salute e della Scienza”, Turin; ²Department of Biomedicine and Prevention, PhD in Immunology, Molecular Medicine and Applied Biotechnology, University of Roma Tor Vergata, Roma; ³Department of Health Science DISSAL, University of Genoa, Unit of Radiology and IRCCS San Martino Hospital, Genoa, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.202

  342

  PDF: 0

• CO27 | Intracerebral hemorrhage in hemophilia A and B: a 10-year prospective multicenter study in Italy (2012–2022) E. Zanon¹, A. Napolitano¹, A. Porreca², F. Demartis³, A. Coppola⁴, C. Santoro⁵, I. Cantori⁶, A. C. Molinari⁷, C. Biasioli⁸, M. Luciani⁹, G. Sottilotta¹⁰, B. Pollio¹¹, A. Borchiellini¹², A. Tosetto¹³, P. Flora¹⁴, P. Simioni¹ | ¹Haemophilia Center, First Chair of Internal Medicine, Department of Medicine, University-Hospital of Padua Medical School, Padua; ²Department of Human Sciences and Promotion of the Quality of Life, Unit of Clinical and Molecular Epidemiology IRCCS San Raffaele Roma Open University, Roma; Unit of Clinical and Molecular Epidemiology IRCCS San Raffaele, Roma; ³Centre for Bleeding Disorders, Careggi University Hospital of Firenze; ⁴Azienda Ospedaliero Universitaria di Parma; ⁵Hematology Division, Umberto I University Hospital of Roma; ⁶Haemophilia Center, Department of Transfusion Medicine, Hospital of Macerata; ⁷IRCCS Istituto Giannina Gaslini, Genova; ⁸Haemophilia and Transfusion Centre, Bufalini Hospital, Cesena; ⁹Children’s Hospital Bambino Gesù, Roma; ¹⁰Haemophilia Center, Department of Onco-Hematology and Radioterapy, Hospital of Reggio Calabria; ¹¹Haemophilia Pediatric Center, Transfusion Medicine, City of Health and Science of Turin; ¹²City of Health and Science of Turin; ¹³Hemorrhagic and Thrombotic Diseases Unit, S. Bortolo Hospital of Vicenza; ¹⁴RCCS Foundation Ca’ Granda Maggiore Policlinico Hospital, Milan, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.233

  331

  PDF: 0

• PO21 | Exploring endothelial damage: the interplay between coagulopathy, capillary leak and vasoplegia in sepsis M. Facci¹, G. Turcato¹, A. Zaboli², L. Filippi¹, P. Ferretto¹, M. Maggi¹, F. Lucente¹, D. Milazzo¹, A. Bresolin¹, M. Marchetti¹ | ¹UOC Medicina Generale, Ospedale Alto Vicentino, Santorso, (VI); ²Innovation, Research and Teaching Service “SABES-ASDAA” of Azienda Sanitaria dell’Alto Adige, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.281

  282

  PDF: 0

• PO44 | Emicizumab in acquired haemophilia A M. Leotta, A. Strangio, A. Ierardi, S. Prejanò, R C. Santoro | Hemostasis and Thrombosis Unit, Department Hemato-Oncology, Azienda Ospedaliero-Universitaria Renato; Dulbecco, Catanzaro, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.307

  307

  PDF: 0

• PO07 | Liver transplant in a case of congenital afibrinogenemia G. Murante^1,2,3, S. Bergonzi^1,2,3, C. Sella^1,2,3, F. Valeri^1,2, C. Dainese^1,2, A. Valpreda⁴, R. Pastorino^1,3, R. Romagnoli⁵, D. Patrono⁵, D. Cussa⁵, S. Martini⁶, B. Bruno^2,3, A. Borchiellini^1,2 | ¹Regional Centre for Hemorrhagic and Thrombotic Diseases, AOU Città della Salute e della Scienza, Torino; ²Division of Hematology, AOU Città della Salute e della Scienza, University of Turin; ³Department of Molecular Biotechnology and Health Sciences, University of Turin; ⁴Central Laboratory Baldi and Riberi, AOU Città della Salute e della Scienza, Torino; ⁵General Surgery 2U - Liver Transplant Center, Molinette Hospital, AOU Città della Salute e della Scienza, Torino; ⁶SSD Hepatic insufficiency and Liver Transplant, AOU Città della Salute e della Scienza, Torino, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.269

  295

  PDF: 0

• PO42 | Acquired Von Willebrad syndrome in patients with myeloproliferative syndrome: literature review and single-center experience A. Strangio, M. Leotta, A. Ierardi, R C. Santoro | UO Emofilia, Emostasi e Trombosi, AOU R Dulbecco, Catanzaro, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.305

  263

  PDF: 0

• CO37 | Assessment of clotting factor activity and sterility in thawed fresh frozen plasma supplied to helicopter emergency medical services for prehospital transfusion D. Romeo¹, M. Marchetti^1,2, M. Testa¹, A. Motta¹, P. Gomez-Rosas¹, G. Ravasio¹, F. Daminelli³, L. Barcella¹, A. Falanga^1,2 | ¹Immunohematology and Transfusion Medicine Department, Hospital Papa Giovanni XXIII, Bergamo; ²School of Medicine and Surgery, University Milano Bicocca, Milan; ³Anesthesia and Resuscitation Department, Hospital Papa Giovanni XXIII, Bergamo, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.244

  303

  PDF: 0