Thrombophilia work-up and clinical outcomes in Indian patients with unprovoked venous and arterial thrombosis aged 18-50 years | BTVB Bioequivalence of von Willebrand factor-containing concentrates: implications for von Willebrand disease | BTVB Cardiovascular risk in hormone replacement therapy | BTVB Direct oral anticoagulants: does one dose fit all? Why, when and how testing | BTVB Cardiovascular risk profile evolution over 15 years: CV-PREVITAL vs Moli-sani Study | BTVB Launch of National Registry for Congenital Hematological Disorders in Palestine: Haemo-PAL | BTVB
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Bleeding, Thrombosis and Vascular Biology

Editor-in-Chief: Giovanni de Gaetano, Italy | eISSN: 2785-5309

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  • Anticoagulation in obese patients: challenges and strategies

    Alice Lipari, Esmeralda Capristo, Antonietta Ferretti, Erica De Candia
    18-09-2025
    https://doi.org/10.4081/btvb.2025.174
    1829
    PDF: 262
    HTML: 195
    XML: 77
  • The key to fibrinolysis and thrombolysis

    Roger Lijnen, Désiré Collen
    09-09-2025
    https://doi.org/10.4081/btvb.2025.368
    1498
    PDF: 256
    HTML: 124
  • Platelet distribution width is associated with cardiovascular mortality in an adult general population

    Benedetta Izzi, Simona Costanzo, Alessandro Gialluisi, Amalia De Curtis, Sara Magnacca, Teresa Panzera, Augusto Di Castelnuovo, Maria Benedetta Donati, Chiara Cerletti, Marc F. Hoylaerts, Giovanni de Gaetano, Licia Iacoviello, *on behalf of the Moli-sani Study Investigators
    27-09-2023
    https://doi.org/10.4081/btvb.2023.83
    2739
    PDF: 408
    Supplementary Material: 97
  • Plasma fibrinogen levels and all-cause and cause-specific mortality in an Italian adult population: results from the Moli-sani study

    Roberta Parisi, Simona Costanzo, Romy de Laat-Kremers, Augusto Di Castelnuovo, Amalia De Curtis, Teresa Panzera, Mariarosaria Persichillo, Chiara Cerletti, Giovanni de Gaetano, Maria Benedetta Donati, Licia Iacoviello, Bas de Laat , for the Moli-sani Study Investigators
    27-01-2023
    https://doi.org/10.4081/btvb.2023.46
    2101
    PDF: 535
    APPENDIX: 178
  • PO44 | PREDICTORS OF ONE-YEAR MORTALITY IN NEWLY DIAGNOSED METASTATIC BREAST CANCER: THE PROGNOSTIC ROLE OF HEMOSTATIC BIOMARKERS AND EARLY THROMBOEMBOLISM M. Marchetti1|2|3, P. Gomez-Rosas1|4|5, S. Bolognini1, C. Ticozzi1, D. Romeo1, F. Schieppati1|3, L. Barcella1|3, F. Petrelli6, A. D'Alessio7, R. Labianca7, A. Falanga1|2|3 | 1Immunohematology and Transfusion Medicine, Hospital Papa Giovanni XXIII, Bergamo, Italy; 2School of Medicine and Surgery, University of Milan Bicocca, Milan, Italy; 3ERN EuroBloodNet; 4Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, The Netherlands; 5Hospital de Oncologia, Unidad Medica de Alta Especialidad (UMAE), Centro Medico Nacional Siglo XXI, Instituto Mexicano del Seguro Social (IMSS), Mexico City, Mexico; 6Oncology Unit, Hospital Treviglio-Caravaggio, Treviglio, Italy; 7Fondazione ARTET Onlus, Bergamo, Italy; *On behalf of the Hypercan Investigators

    Società Italiana di Emostasi e Trombosi
    16-04-2026
    https://doi.org/10.4081/btvb.2026.538
    1
    PDF: 0
  • Cardiovascular risk in hormone replacement therapy

    Doris Barcellona
    09-02-2026
    https://doi.org/10.4081/btvb.2026.411
    1143
    PDF: 233
  • PO09 | CANCER MORTALITY AFTER INCIDENT VENOUS THROMBOEMBOLISM C. Langholm1, N.H. Eide1, K. Hveem2|3|4, N. Van Es5|6, V.M. Morelli1|7, S.K. Braekkan1|7, J.B. Hansen1|7 | 1Thrombosis Research Group, Department of Clinical Medicine, UiT – The Arctic University of Norway, Tromsø, Norway; 2HUNT Research Centre, Department of Public Health and General Practice, Norwegian University of Science and Technology, Levanger, Norway; 3HUNT Center for Molecular and Clinical Epidemiology, Department of Public Health and Nursing, Norwegian University of Science and Technology, Trondheim, Norway; 4Department of Research, St. Olav University Hospital, Trondheim, Norway; 5Department of Vascular Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands; 6Amsterdam Cardiovascular Sciences Pulmonary Hypertension and Thrombosis Amsterdam, the Netherlands; 7Thrombosis Research Center, Department of Internal Medicine, University Hospital of North Norway, Tromsø, Norway

    Società Italiana di Emostasi e Trombosi
    16-04-2026
    https://doi.org/10.4081/btvb.2026.505
    4
    PDF: 0
  • PO11 | Neutrophil cathepsin G and risk of cardiovascular events in patients with diabetes mellitus V. Cammisotto1, F. Baratta2, S. Bartimoccia3, D. Pastori1, N. Cocomello4, V. Castellani5, C. Nocella1, R. Carnevale3, G. Desideri1, F. Violi1, P. Pignatelli1 | 1Department of Clinical, Internal Medicine, Anesthesiological and Cardiovascular Sciences, Sapienza University of Roma; 2Geriatric Unit, Department of Internal Medicine and Medical Specialties, AOU Policlinico Umberto I, Roma; 3Department of Medical-Surgical Sciences and Biotechnologies, Sapienza University of Roma; 4Department of Anatomical Sciences, Histological, Legal Medical and Locomotor, Sapienza University of Roma; 5Department of Experimental Medicine, Sapienza University of Roma, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.273
    463
    PDF: 0
  • https://BioRender.com/zrlk3rh

    The subtle red line between combating and resolving inflammation in the cardiovascular disease, a “silent sniper”

    Ciarán Kennedy, Luke J. Conroy, Braden Millar, Monica de Gaetano
    30-06-2025
    https://doi.org/10.4081/btvb.2025.187
    1313
    PDF: 334
  • PO16 | EPIDEMIOLOGY, CLINICAL CHARACTERISTICS, AND OUTCOMES OF PROVOKED AND UNPROVOKED PULMONARY EMBOLISM IN A MULTICULTURAL ISRAELI POPULATION R. Farah1, N.L. Bragazzi2|3|4, H.İ. Ceylan5, Ł. Szarpak6|7|8|9, W. Mahajni1, N. Ashqar1, A. M. Fioretti10, R. Khamisy-Farah11 | 1Internal Medicine B Department, Ziv Medical Center, Azrieli Faculty of Medicine, Bar-Ilan University, Galilee, Safed, Israel; 2Laboratory for Industrial and Applied Mathematics, Department of Mathematics and Statistics, York University, Toronto, Canada; 3Postgraduate School of Public Health, Department of Health Sciences, University of Genoa, Italy; 4UNESCO Chair, Health Anthropology, Biosphere and Healing Systems, University of Genoa, Italy; 5Physical Education and Sports Teaching Department, Faculty of Sports Sciences, Atatürk University, Erzurum, Turkey; 6Department of Clinical Research and Development, LUXMED Group, Warsaw, Poland; 7Institute of Medical Science, Collegium Medicum, The John Paul II Catholic University of Lublin, Lublin, Poland; 8The World Academic Council of Emergency Medicine, Sarasota, FL, USA; 9Henry JN Taub Department of Emergency Medicine, Baylor College of Medicine, Houston, TX, USA; 10Cardio-Oncology Unit, IRCCS Istituto Tumori “Giovanni Paolo II”, Bari, Italy; 11Clalit Health Service, Azrieli Faculty of Medicine, Bar-Ilan University, Galilee, Safed, Israel

    Società Italiana di Emostasi e Trombosi
    16-04-2026
    https://doi.org/10.4081/btvb.2026.511
    4
    PDF: 0
  • Management of anticoagulation in atrial fibrillation patients in Italy: insight from the Atrial Fibrillation-Survey on Anticoagulated Patients Register (AF-START)

    Daniela Poli, Walter Ageno, Emilia Antonucci, Salvatore Bradamante, Eugenio Bucherini, Paolo Chiarugi, Antonio Chistolini, Benilde Cosmi, Anna Falanga, Antonio Insana, Domenico Lione, Rosa Maria Lombardi, Giuseppe Malcangi, Rossella Marcucci, Giuliana Martini, Lucilla Masciocco, Carmelo Paparo, Daniele Pastori, Simona Pedrini, Vittorio Pengo, Pasquale Pignatelli, Andrea Toma, Sophie Testa, Gualtiero Palareti
    27-06-2023
    https://doi.org/10.4081/btvb.2023.84
    1792
    PDF: 503
    Supplementary File: 232
  • Unveiling the “common soil” of cardiovascular disease and cancer

    Licia Iacoviello, Maria Benedetta Donati
    24-02-2025
    https://doi.org/10.4081/btvb.2025.167
    1306
    PDF: 351
  • CO03 | Early discharge and home treatment of low-risk pulmonary embolism: a cohort study E. Ruggeri1, L. Vulcano1, W. Ageno2, F. Cortellaro3, M.P. Donadini3,4 | 1Scuola di Medicina, Università degli Studi dell’Insubria, Varese; 2Dipartimento di Medicina, Università degli Studi di Padova; 3Pronto Soccorso e Medicina d’Urgenza, Ospedale di Circolo, ASST Sette Laghi, Varese; 4Dipartimento di Medicina e Chirurgia, Università degli Studi dell’Insubria, Varese, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.208
    511
    PDF: 0
  • PO25 | EVOLUTION OF ANTICOAGULANT STRATEGIES AND CLINICAL OUTCOMES IN CANCER-ASSOCIATED THROMBOSIS: A LONGITUDINAL ANALYSIS OF THE START2 REGISTRY ONCO-VTE M. Marchetti1|2, T. Zollner1|2, OC. Cretu1|2, A. Chistolini3, R. Pancani4, L. Puccetti5, P. Sivera6, W. Ageno7, G. Elmi8, V. Fregoni9, V. Tonelli10, E. Antonucci11, D. Poli11|12, A. Falanga1|2, L. Barcella1|2 | 1Hemostasis & Thrombosis Center, Department of Transfusion Medicine, Papa Giovanni XXIII Hospital, Bergamo Italy; 2ERN EuroBloodNet; 3Hematology Unit, Department of Translational and Precision Medicine, Sapienza University of Rome, Rome, Italy; 4Pulmonary Unit, Hospital of Siena, University of Siena, Siena, Italy; 5Hemostasis and Thrombosis Unit, Hospital of Siena, University of Siena, Siena, Italy; 6Haematology Unit, Ordine Mauriziano Hospital, Turin, Italy; 7Department of Medicine, University of Padua, Padua, Italy; 8Department of Medicine, Maggiore Hospital, Bologna, Italy; 9Department of Medicine, Sondalo Hospital, Sondalo, Italy; 10Angiology Unit, Sant'Eugenio Hospital, Rome, Italy; 11Arianna Anticoagulazione Foundation, Bologna, Italy; 12Department of Critical Care Medicine, Thrombosis Centre, Azienda Ospedaliera Universitaria Careggi, Firenze, Italy

    Società Italiana di Emostasi e Trombosi
    16-04-2026
    https://doi.org/10.4081/btvb.2026.520
    4
    PDF: 0
  • CO27 | Intracerebral hemorrhage in hemophilia A and B: a 10-year prospective multicenter study in Italy (2012–2022) E. Zanon1, A. Napolitano1, A. Porreca2, F. Demartis3, A. Coppola4, C. Santoro5, I. Cantori6, A. C. Molinari7, C. Biasioli8, M. Luciani9, G. Sottilotta10, B. Pollio11, A. Borchiellini12, A. Tosetto13, P. Flora14, P. Simioni1 | 1Haemophilia Center, First Chair of Internal Medicine, Department of Medicine, University-Hospital of Padua Medical School, Padua; 2Department of Human Sciences and Promotion of the Quality of Life, Unit of Clinical and Molecular Epidemiology IRCCS San Raffaele Roma Open University, Roma; Unit of Clinical and Molecular Epidemiology IRCCS San Raffaele, Roma; 3Centre for Bleeding Disorders, Careggi University Hospital of Firenze; 4Azienda Ospedaliero Universitaria di Parma; 5Hematology Division, Umberto I University Hospital of Roma; 6Haemophilia Center, Department of Transfusion Medicine, Hospital of Macerata; 7IRCCS Istituto Giannina Gaslini, Genova; 8Haemophilia and Transfusion Centre, Bufalini Hospital, Cesena; 9Children’s Hospital Bambino Gesù, Roma; 10Haemophilia Center, Department of Onco-Hematology and Radioterapy, Hospital of Reggio Calabria; 11Haemophilia Pediatric Center, Transfusion Medicine, City of Health and Science of Turin; 12City of Health and Science of Turin; 13Hemorrhagic and Thrombotic Diseases Unit, S. Bortolo Hospital of Vicenza; 14RCCS Foundation Ca’ Granda Maggiore Policlinico Hospital, Milan, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.233
    524
    PDF: 0
  • CS01 | Elucidating the evil relationship of metabolic dysfunction–associated fatty liver disease with cardiovascular comorbidities: the complex interplay among hypercoagulability, inflammation and liver fibrosis G. Gagliardi, E. Campello, A. Napolitano, B. Stocco, C. Di Gesù, G. Gobbo, I. Condonato, M. Allegra, G. Camporese, P. Scarinzi, R. Pesavento, F. Bilora, C. Bulato, A. Benetti, C. Samà, C. Portinari, G. Antonello, C. Goffi, L. Di Daniel, A. Zambon, L. Fabris, P. Simioni | First Chair of Internal Medicine, Department of Medicine, University-Hospital of Padua Medical School, Padua, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.196
    643
    PDF: 0
  • CO45 | Role of urinary 11-dehydro-thromboxane B2 as a predictor of preeclampsia in pregnant high-risk women on low-dose aspirin treatment P.G.M. Simeone1, R. Liani1, M. Alfonsetti1, A. Ricci1, V. Cianci1, S. Zeeba2, M. Molino3, S. Palma2, R. Malizia4, M. Luongo4, A. Di Castelnuovo5, F. Cipollone1, F. D’antonio6, F. Ricci2, G. Renda2, F. Santilli1 | 1Department of Medicine and Aging Sciences, Center for Advanced Studies and Technology, University of Chieti; 2Department of Neuroscience, Imaging and Clinical Sciences, G D’Annunzio University of Chieti-Pescara, Chieti; University Cardiology Division, Heart Department, Policlinico SS Annunziata, Chieti; 3Clinical Pathology of Chieti University Hospital; 4Immunotransfusion Service, Clinical Haematology of Chieti University Hospital, Chieti; 5Mediterranea Cardiocentro, Napoli; 6Centre for Fetal Care and High-Risk Pregnancy, Department of Obstetrics and Gynecology, University of Chieti, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.251
    451
    PDF: 0
  • CO10 | Multidimensional risk assessment of venous thromboembolism: an observational study comparing the Padua prediction score, Barthel index, and quality of life in hospitalized patients A. Mameli, S. Cornacchini, P. Schirru, F. Marongiu, D. Barcellona | Hemostasis and Thrombosis Unit, University of Cagliari, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.214
    542
    PDF: 0
  • CO16 | The predictive value of high-sensitivity C-reactive protein for assessing thrombosis risk in non-small cell lung cancer P. Gomez-Rosas1,2, M. Marchetti1,3, L. Russo1, C.J. Tartari1, S. Bolognini1, C. Ticozzi1, F. Schieppati1, A. D’Alessio4, R. Labianca5, A. Falanga1,3 All on behalf of the Hypercan Investigators | 1Hospital Papa Giovanni XXIII, Bergamo, Italy; 2Cardiovascular Research Institute Maastricht, CARIM, Maastricht University, Maastricht, the Netherlands; 3School of Medicine and Surgery, University of Milan Bicocca, Italy; 4University Vita-Salute San Raffaele, Milan, Italy; 5Fondazione ARTET Onlus, Bergamo, Italy

    22-10-2025
    https://doi.org/10.4081/btvb.2025.220
    496
    PDF: 0
  • PO47 | VENOUS THROMBOEMBOLISM IN BREAST CANCER: INSIGHTS FROM A SINGLE-CENTER COHORT S. Kozhukhov, N. Dovganych | SI “NSC “The M. D. Strazhesko Institute of Cardiology, Clinical and Regenerative Medicine of the National Academy of Medical Sciences of Ukraine, Kyiv, Ukraine; 2Cardio-Oncology Center, Kyiv, Ukraine

    Società Italiana di Emostasi e Trombosi
    16-04-2026
    https://doi.org/10.4081/btvb.2026.540
    2
    PDF: 1
  • Unlocking the potential of statins for venous thromboembolism prophylaxis in cancer: why conduct the STAT-CAT trial?

    Jean M. Connors, Robert J. Glynn, Alok A. Khorana, Paul M. Ridker
    16-04-2026
    https://doi.org/10.4081/btvb.2026.450
    1
    PDF: 1
  • Major bleedings in mechanical prosthetic heart valves patients on Vitamin K antagonist treatment. Data from the PLECTRUM Study

    Daniela Poli, Emilia Antonucci, Gualtiero Palareti, Roberto Facchinetti, Pietro Falco, Giuseppina Serricchio, Teresa Lerede, Lucilla Masciocco, Paolo Gresele, Sophie Testa
    27-07-2022
    https://doi.org/10.4081/btvb.2022.34
    5317
    PDF: 494
    Supplementary Files: 193
  • Thromboprophylaxis in primary brain cancer

    Eva N. Hamulyák, Barbara A. Hutten, Nick van Es
    16-04-2026
    https://doi.org/10.4081/btvb.2026.455
    9
    PDF: 1
  • Treatment of venous thromboembolism in pregnancy: findings from the RIETE Registry

    Paolo Prandoni, Franca Bilora, Raffaele Pesavento, Giorgina Salgueiro, Angeles Blanco-Molina, Raquel Lòpez-Reyes, Manuel Monreal, and the RIETE Investigators
    23-05-2022
    https://doi.org/10.4081/btvb.2022.28
    5541
    PDF: 560
    APPENDIX: 0
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Vol. 5 No. 1 (2026)
A lifetime in biomedical research: an interview with Silvio Garattini
Americo Bonanni
12 March 2026
Vol. 5 No. 1 (2026)
Hemophilia-free mind: a call to action
Tiziano Martini et al.
10 March 2026
Vol. 5 No. 1 (2026)
Comments on “Low-dose aspirin for preventing intrauterine growth restriction and pre-eclampsia in sickle cell pregnancy in Nigeria (PIPSICKLE): a...
Sistiana Aiello et al.
10 March 2026

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Bleeding, Thrombosis and Vascular Biology

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