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• CO-82 | ACQUIRED SEVERE FACTOR XIII DEFICIENCY AS THE INITIAL PRESENTATION OF PAEDIATRIC ACUTE PROMYELOCYTIC LEUKAEMIA C. Vernarecci, G. Gazzelli, L. Banov, F. Marotta, F. Giacopelli, B. Tappino, B. Antonioli, A.C. Molinari | IRCCS Istituto Giannina Gaslini, Genova, Italy

  Angelo Claudio Molinari

  14-10-2026

  https://doi.org/10.4081/btvb.2026.692

  67

  PDF: 13
• 

  PO08 | NEXT-GENERATION THROMBOLYTICS: ENGINEERING STREPTOKINASE FOR ENHANCED ACTIVITY AND REDUCED IMMUNOGENICITY M. Kanwal^1|2 | ¹Consiglio Nazionale delle Ricerche, Naples, Italy; ²Department of Environmental, Biological and Chemical Sciences and Technologies, University of Campania "Luigi Vanvitelli", Italy

  ICTHIC 2026

  16-04-2026

  https://doi.org/10.4081/btvb.2026.504

  497

  PDF: 85

• CO31 | Immune system profiling in FVIII-treated and emicizumab-treated pediatric HA patients A. Cottonaro¹, S. Akula¹, B. Pollio², I. Ricca², T. Martini², J. Agnelli Giacchello³, P. Sciancalepore³, R. Santi³, A. Follenzi^1,3, S. Merlin¹ | ¹Università del Piemonte Orientale, Health Sciences, Novara; ²A.O. Città della Salute e della Scienza, SIMT Immunohematology and Transfusion Medicine Service, Diagnostic Department, Torino; ³Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo, Alessandria, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.238

  645

  PDF: 15
• 

  Growing weapons to fight hemophilia

  Pier Mannuccio Mannucci

  23-02-2023

  https://doi.org/10.4081/btvb.2023.64

  1491

  PDF: 585
• 

  PO44 | PREDICTORS OF ONE-YEAR MORTALITY IN NEWLY DIAGNOSED METASTATIC BREAST CANCER: THE PROGNOSTIC ROLE OF HEMOSTATIC BIOMARKERS AND EARLY THROMBOEMBOLISM M. Marchetti^1|2|3, P. Gomez-Rosas^1|4|5, S. Bolognini¹, C. Ticozzi¹, D. Romeo¹, F. Schieppati^1|3, L. Barcella^1|3, F. Petrelli⁶, A. D'Alessio⁷, R. Labianca⁷, A. Falanga^1|2|3 | ¹Immunohematology and Transfusion Medicine, Hospital Papa Giovanni XXIII, Bergamo, Italy; ²School of Medicine and Surgery, University of Milan Bicocca, Milan, Italy; ³ERN EuroBloodNet; ⁴Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, The Netherlands; ⁵Hospital de Oncologia, Unidad Medica de Alta Especialidad (UMAE), Centro Medico Nacional Siglo XXI, Instituto Mexicano del Seguro Social (IMSS), Mexico City, Mexico; ⁶Oncology Unit, Hospital Treviglio-Caravaggio, Treviglio, Italy; ⁷Fondazione ARTET Onlus, Bergamo, Italy; *On behalf of the Hypercan Investigators

  ICTHIC 2026

  16-04-2026

  https://doi.org/10.4081/btvb.2026.538

  475

  PDF: 108
• 

  The therapeutic landscape of cancer-associated splanchnic vein thrombosis

  Alessia Abenante, Filippo Catalani, Walter Ageno

  16-04-2026

  https://doi.org/10.4081/btvb.2026.458

  323

  PDF: 154

• PO33 | Whole blood hypercoagulable profiles in patients with rheumatoid arthritis L. Spiezia¹, A. Giollo², C. Samà¹, A. Benetti¹, L. Di Luozzo², M. Salvato², A. Doria², P. Simioni¹ | ¹First Chair of Internal Medicine, Thrombotic and Hemorrhagic Diseases Unit, Department of Medicine, University Hospital of Padova; ²Rheumatology Unit, Department of Medicine, University Hospital of Padova, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.296

  634

  PDF: 18

• CO03 | Early discharge and home treatment of low-risk pulmonary embolism: a cohort study E. Ruggeri¹, L. Vulcano¹, W. Ageno², F. Cortellaro³, M.P. Donadini^3,4 | ¹Scuola di Medicina, Università degli Studi dell’Insubria, Varese; ²Dipartimento di Medicina, Università degli Studi di Padova; ³Pronto Soccorso e Medicina d’Urgenza, Ospedale di Circolo, ASST Sette Laghi, Varese; ⁴Dipartimento di Medicina e Chirurgia, Università degli Studi dell’Insubria, Varese, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.208

  673

  PDF: 25

• PO058 | IMMUNOMODULATORY EFFECTS OF FOSTAMATINIB IN A PATIENT WITH EVANS SYNDROME, TRIPLE-POSITIVE ANTIPHOSPHOLIPID ANTIBODIES AND RELATED COAGULATION ABNORMALITIES S. Bergonzi^1|2|4, G. Murante^1|2|4, M. Capetta^1|2|4, F. Valeri^1|2, C. Dainese^1|2, A. Valpreda^3|4, R. Pastorino^3|4, F. Bocchi^3|4, B. Bruno^2|4, A. Borchiellini^1|2 | ¹Regional Centre for Hemorrhagic and Thrombotic Diseases; ²Division of Hematology; ³Central Laboratory Baldi and Riberi, AOU Città della Salute e della Scienza, Università di Torino, Italy; ⁴Department of Molecular Biotechnology and Health Sciences, University of Turin, Italy

  Sara Bergonzi

  26-10-2026

  https://doi.org/10.4081/btvb.2026.874

  23

  PDF: 12

• CO090 | DIRECT ORAL ANTICOAGULANTS IN THE SECONDARY PREVENTION OF VENOUS THROMBOEMBOLISM IN PATIENTS WITH SEVERE INHERITED THROMBOPHILIA: A REAL-WORLD MULTICENTER STUDY A. Tufano¹, I.L. Calcaterra¹, E. Valeriani², E. Cimino¹, P. Madonna³, A. Guida⁴, P. Rufolo¹, F. Strano¹, R. Russo¹, A. Casoria⁵, M. Amitrano⁵, P. Pignatelli², M. Di Minno¹ | ¹Department of Clinical Medicine and Surgery, University of Naples, Federico II, Napoli, Italy; ²Department of Internal Medicine, Endocrine and Metabolic Sciences, and Infectious Diseases. Umberto I Hospital of Roma, Italy; ³Thrombotic Unit, Ospedale del Mare, Napoli, Italy; ⁴Center for Congenital Bleeding Disorders and Thrombosis, AOU S.Giovanni di Dio and Ruggi d'Aragona, Salerno, Italy; ⁵UOC Medicina Interna, AORN Moscati, Avellino, Italy

  Antonella Tufano

  26-10-2026

  https://doi.org/10.4081/btvb.2026.792

  36

  PDF: 12

• CO-02 | NEONATAL GENOMIC SCREENING ENABLES PRE-SYMPTOMATIC DIAGNOSIS AND PREVENTIVE MANAGEMENT OF HEMOPHILIA B. Borsellino¹, B. Pollio¹, P. Quarello^2|3, T. Martini¹, C. Linari⁴, M. Carabotta⁵, C. Cagnazzo², S. Minucci⁶, F. Fagioli^2|3 | ¹Paediatric Haemophilia Centre, Immune-Haematology and Transfusion Medicine, University Hospital "Città della Salute e della Scienza", Torino, Italy; ²Paediatric Onco-Hematology, Stem Cell Transplantation and Cellular Therapy Division, Regina Margherita Children’s Hospital, Torino, Italy; ³Department of Paediatric and Public Health Sciences, University of Turin, Italy; ⁴Department of Laboratory Medicine, Azienda Ospedaliera Universitaria Città della Salute e della Scienza, Torino, Italy; ⁵Department of Pediatrics, G. d'Annunzio University, Chieti, Italy; ⁶Italian Institute for Genomic Medicine, IRCCS, Candiolo, Italy

  Beatrice Borsellino

  14-10-2026

  https://doi.org/10.4081/btvb.2026.612

  141

  PDF: 17

• PO101 | COMPREHENSIVE EVALUATION OF COAGULATION PROFILES IN REFRACTORY MODERATE-TO-SEVERE ULCERATIVE COLITIS L. Spiezia¹, G. Di Lecce², B. Barberio², M. Zanconato², E. Bicego¹, C. Samà¹, B. Serena¹, M. De Bona³, A. Buda³, F. Zingone², E.V. Savarino², P. Simioni¹ | ¹First Chair of Internal Medicine, Department of Medicine (DIMED), Padova University Hospital, Padova, Italy; ²Gastroenterology Unit, Department of Surgery, Oncology and Gastroenterology (DISCOG), University of Padova, Padova, Italy; ³Gastroenterology Unit, Department of Oncological Gastrointestinal Surgery, S. Maria del Prato Hospital, Feltre, Italy

  Luca Spiezia

  26-10-2026

  https://doi.org/10.4081/btvb.2026.917

  27

  PDF: 13

• PO029 | IMPACT OF HEPATOCELLULAR CARCINOMA ON CIRCULATING RETICULATED PLATELETS IN PATIENTS WITH AND WITHOUT LIVER CIRRHOSIS S. Toffanin¹, P. Guerra², B. Serena¹, C. Bulato¹, A. Montagna¹, C.M. Radu¹, A. Bonaldo², S. Cagnin², C. Soldà³, M.D. Rizzato³, S. Lonardi³, F. Bergamo³, A. Zanetto⁴, E. Pinto⁴, M. Senzolo⁴, S. Montagnese², E. Campello¹, A. Martini², P. Simioni¹ | ¹Thrombotic and Hemorrhagic Diseases Unit, General Internal Medicine, Department of Medicine, University of Padua, Padova, Italy; ²Internal Medicine and Hepatology Unit, Department of Medicine, University of Padua, Padova, Italy; ³Department of Oncology, Veneto Institute of Oncology IOV-IRCCS, Padova, Italy; ⁴Oncology, and Gastroenterology Unit, Department of Surgery, University of Padua, Padova, Italy

  Serena Toffanin

  26-10-2026

  https://doi.org/10.4081/btvb.2026.845

  22

  PDF: 12
• 

  PO61 | RISK FACTORS FOR INTRACRANIAL HEMORRHAGE: AN UMBRELLA REVIEW TO INFORM MACHINE LEARNING PREDICTION MODELS IN GLIOMA PATIENTS RECEIVING ANTICOAGULATION T.A. Adeyemo, S. Greenley, F. Ware, W. Jones, A. Maraveyas, F. Haque | ¹Centre of Excellence for Data Science, Artificial Intelligence and Modelling DAIM, Faculty of Science and Engineering, University of Hull, UK; ²Hull York Medical School, Hull, UK; ³Academic Library Services, University of Hull, UK; ⁴NHS Humber Health Partnership, Hull, UK

  ICTHIC 2026

  16-04-2026

  https://doi.org/10.4081/btvb.2026.552

  533

  PDF: 116
• 

  OC02 | INCIDENCE AND PREDICTORS OF ARTERIAL THROMBOSIS IN CANCER PATIENTS: RESULTS FROM THE PROSPECTIVE COMPASS-ARTERIAL CANCER ASSOCIATED THROMBOSIS (COMPASS-ARTECAT) STUDY M. Drakopoulou¹, I. Diamandoulaki², P. Baglaridis¹, P. Las Casa³, P. Van Dreden⁴, K. Toutouzas¹, G. Gerotziafas^4|5 | ¹First Department of Cardiology, School of Medicine, National and Kapodistrian University of Athens, Hippokration General Hospital, Athens, Greece; ²Department of Electrical and Computer Engineering, Aristotle University of Thessaloniki, Thessaloniki, Greece; ³Sorbonne University, INSERM UMR_S_938, CRSA, Research Department "Cancer, Vessels, Biology and Therapeutics" (CaVITE), Research Group "Cancer-Angiogenesis-Thrombosis and Haemostasis," Thrombosis Center, University Institute of Cancerology (UIC), Saint Antoine University Hospital Assistance Publique Hôpitaux de Paris (AP-HP) Paris France; ⁴Diagnostica Stago, clinical research, Gennevilliers, France; ⁵Center of Translational Research and Education, Department of Pathology and Laboratory Medicine, Loyola University Stritch School of Medicine, Maywood, Ill., USA

  ICTHIC 2026

  16-04-2026

  https://doi.org/10.4081/btvb.2026.486

  518

  PDF: 131

• PO45 | Routine prophylaxis with PD-FX concentrate in severe inherited FX deficiency: a case report S. Linari, L. Pieri, M. Attanasio, F. Salvianti, M. Coppo, E. Grisanti, F. Demartis, R. Fjerza, G. Castaman | Centre for Bleeding Disorders and Coagulation, Azienda Ospedaliera Universitaria Careggi, Firenze, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.308

  626

  PDF: 21

• CO18 | Relationship between gut permeability and PCSK9 in heterozygous familial hypercholesterolemia V. Castellani¹, V. Cammisotto², F. Baratta², S. Bartimoccia³, C. Nocella², L. D’erasmo¹, N. Cocomello², C. Barale⁴, R. Scicali⁵, I. Russo⁴, F. Purrello⁵, R. Carnevale³, F. Violi², M. Arca¹, P. Pignatelli² | ¹Department of Translational and Precision Medicine, Sapienza University of Roma; ²Department of Clinical, Internal Medicine, Anesthesiology and Cardiovascular Sciences, Sapienza University of Roma; ³Department of Medical-Surgical Sciences and Biotechnologies, Sapienza University of Roma; ⁴Department of Clinical and Biological Sciences, University of Turin; ⁵Department of Clinical and Experimental Medicine, Internal Medicine, University of Catania, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.222

  607

  PDF: 16

• PO128 | FROM SEVERE THROMBOSIS TO SUCCESSFUL PREGNANCIES: ORTHOTOPIC LIVER TRANSPLANTATION IN INHERITED AFIBRINOGENEMIA WITH BUDD–CHIARI SYNDROME G. Murante^1|2|6, S. Bergonzi^1|2|6, M. Capetta^1|2|6, F. Valeri^1|2, C. Dainese^1|2, A. Valpreda⁴, R. Pastorino^1|6, F. Bocchi^1|6, R. Romagnoli⁵, S. Martini³, B. Bruno^2|6, A. Borchiellini^1|2 | ¹Regional Centre for Hemorrhagic and Thrombotic Diseases; ²Division of Hematology; ³SSD Hepatic insufficiency and Liver Transplant; ⁴Central Lab. Baldi and Riberi; ⁵General Surgery 2U - Liver Transplant Center, Molinette Hospital, AOU Città della Salute e della Scienza di Torino, Italy; ⁶Dep. of Molecular Biotechnology and Health Sciences, University of Turin, Italy

  Giovanni Murante

  26-10-2026

  https://doi.org/10.4081/btvb.2026.944

  24

  PDF: 12

• PO070 | INFECTIVE ENDOCARDITIS AND ISCHEMIC CEREBRAL EVENTS IN A PATIENT WITH SYSTEMIC LUPUS ERYTHEMATOSUS AND TRIPLE ANTIPHOSPHOLIPID POSITIVITY: THE ROLE OF ANTICOAGULATION IN PRIMARY PREVENTION T. Marrazzo¹, M.P. Ursi², R. Andini¹, R. Albisinni³ | ¹UOC Med Interna e dei Trapianti; ²UOC Mecau; ³UOC CCH generale, Osp. Monaldi AORN dei Colli, Napoli, Italy

  Tommaso Marrazzo

  26-10-2026

  https://doi.org/10.4081/btvb.2026.886

  27

  PDF: 11

• CO105 | THALIDOMIDE FOR RECURRENT GASTROINTESTINAL BLEEDING IN RARE BLEEDING DISORDERS AND VENOUS MALFORMATIONS: A MONOCENTRIC EXPERIENCE M. De Siati^1|2, F.G. Perretta^1|2, F. Ricci^1|2, A. Ferretti¹, M. Comand^1|2, S. Sorrentino¹, L. D’Innocenzo^1|2, D. Feliciani², B. Funaro², M.E. Riccioni³, A. Gasbarrini^2|4, E. De Candia^1|2 | ¹UOSD Malattie Emorragiche e Trombotiche, Fondazione Policlinico Agostino Gemelli IRCCS, Roma 00168, Italy; ²Department of Translational Medicine and Surgery, Catholic University of the Sacred Heart, Roma, Italy; ³Digestive Endoscopy Unit, Fondazione Policlinico Universitario Agostino Gemelli, IRCCS, Università Cattolica del Sacro Cuore, Largo Agostino Gemelli, Roma 00168, Italy; ⁴Department of Medical and Surgical Sciences, Digestive Disease Center, Universitary Policlinic Agostino Gemelli Foundation IRCCS, Roma, Italy

  Silvia Sorrentino

  26-10-2026

  https://doi.org/10.4081/btvb.2026.807

  43

  PDF: 8

• CO-28 | SYNERGISTIC EFFECT OF RECOMBINANT FACTOR INFUSION ON THROMBIN GENERATION IN HEMOPHILIA PATIENTS UNDER EMICIZUMAB OR CONCIZUMAB PROPHYLAXIS F. Bocchi^1|2, R. Pastorino^1|2, G. Murante^1|2|3, S. Bergonzi^1|2|3, M. Capetta^1|2|3, F. Valeri^2|3, C. Dainese^2|3, A. Valpreda⁴, B. Bruno^1|3, A. Borchiellini^2|3 | ¹Department of Molecular Biotechnology and Health Sciences, University of Turin, Italy; ²Regional Centre for Thrombotic and Hemorrhagic Diseases, AOU Città della salute e della Scienza di Torino, Italy; ³Division of Hematology, AOU Città della Salute e della Scienza, University of Turin, Italy; ⁴Central Lab Baldi and Riberi, AOU Città della salute e della Scienza di Torino, Italy

  Francesca Bocchi

  14-10-2026

  https://doi.org/10.4081/btvb.2026.638

  62

  PDF: 22
• 

  Diagnostic challenges in current laboratory practice at Italian Hemophilia Centers: findings from a nationwide survey

  Tiziano Martini, Alessandra Valpreda, Marina Marchetti, Alberto Catalano, Laura Contino, Raimondo De Cristofaro, Augusto Bramante Federici, Ilaria Quaglia, Rossana Rossi, Rita Carlotta Santoro, Armando Tripodi, Angelo Claudio Molinari

  12-03-2026

  https://doi.org/10.4081/btvb.2026.431

  430

  PDF: 112

  Supplementary: 52

• PO111 | A RARE CASE OF ACUTE PROMYELOCYTIC LEUKAEMIA PRESENTING WITH A PURELY THROMBOTIC DISSEMINATED INTRAVASCULAR COAGULATION PHENOTYPE L. Colavolpe, M. Provisione, L. Appio, S. Tupputi, N. Mumoli | ASST Valle Olona, Busto Arsizio, VA, Italy

  Lucia Colavolpe

  26-10-2026

  https://doi.org/10.4081/btvb.2026.927

  26

  PDF: 10

• CO078 | METABOLOMIC AND LIPOPROTEOMIC MODULATION FOLLOWING INCLISIRAN TREATMENT IN DYSLIPIDEMIC PATIENTS J. Patrussi¹, A. Vignoli^1|2, L. Tenori^1|2, A. Sorrentino³, M. Berteotti^3|4, E. Lotti⁴, F. Crudele⁴, G. Ciarrocca Taranta³, A.A. Rogolino⁴, G. Barbieri³, A.M. Gori^3|4, R. Marcucci^3|4 | ¹Dep. of Chemistry "Ugo Schiff", University of Florence, Sesto Fiorentino, Italy; ²Magnetic Resonance Center (CERM), University of Florence, Sesto Fiorentino, Italy; ³Dep. of Experimental and Clinical Medicine, University of Florence, Firenze, Italy; ⁴Azienda Ospedaliero-Universitaria Careggi, Firenze, Italy

  Andrea Sorrentino

  26-10-2026

  https://doi.org/10.4081/btvb.2026.780

  42

  PDF: 11

• CO-80 | EMICIZUMAB PLASMA CONCENTRATIONS AND CLINICAL OUTCOMES IN ACQUIRED HEMOPHILIA A: A REAL-WORLD SINGLE-CENTER EXPERIENCE C. Simion^1|2, E. Zanon^1|2, C. Bulato¹, B. Stocco^1|2, F. Righetto¹, F. Sartorello¹, P. Simioni^1|2 | ¹First Chair of Internal Medicine and Thrombotic and Haemorrhagic Diseases Unit, Department of Medicine, Padova University Hospital, Italy; ²Hemophilia Center, Padova University Hospital, Italy

  Chiara Simion

  14-10-2026

  https://doi.org/10.4081/btvb.2026.690

  53

  PDF: 16
• 

  PO05 | DESIGN, SYNTHESIS, AND BIOLOGICAL EVALUATION OF NOVEL IMATINIB AND NILOTINIB ANALOGUES EXPRESSING ENHANCED ANTIPLATELET AND ANTICANCER ACTIVITIES D. Pantazi¹, L. Pechlivani¹, A. Kosma¹, K. Lalechou¹, M.G. Siskos², D. Alivertis³, A.D. Tselepis¹ | ¹Atherothrombosis Research Centre, Laboratory of Biochemistry, Department of Chemistry, University of Ioannina, Greece; ²Laboratory of Organic Chemistry, Department of Chemistry, University of Ioannina, Greece; ³Department of Biological Applications and Technology, University of Ioannina, Greece

  ICTHIC 2026

  16-04-2026

  https://doi.org/10.4081/btvb.2026.501

  556

  PDF: 104

• PO95 | Idiopathic thrombocytopenic purpura in tuberculosis M. Shani | Università di Medicina Tirana, Albania

  22-10-2025

  https://doi.org/10.4081/btvb.2025.365

  648

  PDF: 17

• CO30 | Joint prosthetic surgery in patients with hemophilia A: clinical-functional outcomes and quality of life E. Zanon¹, A. Napolitano¹, A. Berizzi², P. Simioni¹ | ¹Haemophilia Center, First Chair of Internal Medicine, Department of Medicine, University-Hospital of Padua Medical School, Padua; ²Orthopedics and Traumatology Unit, University-Hospital of Padua Medical School, Padua, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.236

  697

  PDF: 33
• 

  How to manage antithrombotic treatments in thrombocytopenic patients with cancer. Comments on the European Haematology Association guidelines

  Anna Falanga, Hugo Ten Cate, Bianca Rocca

  27-01-2023

  https://doi.org/10.4081/btvb.2023.60

  1314

  PDF: 576