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• CO24 | Extracellular vesicles profiles in patients with wild-type transthyretin amyloidosis S. Toffanin¹, L. Spiezia¹, C.M. Radu¹, A. Napolitano¹, A. Benetti¹, C. Samà¹, E. Campello¹, L. De Michieli², G. Sinigiani², A. Cipriani², P. Simioni¹ | ¹First Chair of Internal Medicine, Department of Medicine, University-Hospital of Padua Medical School, Padua; ²Department of Cardiac, Thoracic and Vascular Sciences and Public Health, University of Padua, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.230

  684

  PDF: 14

• PO06 | Extracellular vesicles profiles in patients with porto-sinusoidal vascular disease S. Toffanin¹, E. Campello¹, A. Zanetto², C. M. Radu¹, E. Pinto², K. Fernande², C. Bulato¹, B. Serena¹, L. Spiezia¹, P. Burra², M. Senzolo², P. Simioni¹ | ¹First Chair of Internal Medicine, Department of Medicine, University Hospital of Padua Medical School, Padua; ²Department of Surgery Oncology and Gastroenterology, Gastroenterology and Multivisceral Transplant Unit, University Hospital of Padua, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.268

  629

  PDF: 11
• 

  Coagulome and tumor microenvironment: impact of oncogenes, cellular heterogeneity and extracellular vesicles

  Nadim Tawil, Lata Adnani, Janusz Rak

  16-05-2024

  https://doi.org/10.4081/btvb.2024.109

  1141

  PDF: 1122
• 

  PO01 | MELANOMA-DERIVED EXTRACELLULAR VESICLES DRIVE VON WILLEBRAND FACTOR–DEPENDENT THROMBOSIS AND METASTASIS Y. Wang^1|2, X. Liu¹, T. Downar³, A. Topuz⁴, A. Bauer¹, J. Kött^1|5, K. Nekipelov⁶, S. Brenna⁷, G. Bendas⁶, B. Puig⁷, S. Schneider¹, D. Fedosov⁴, C. Gorzelanny¹ | ¹Department of Dermatology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; ²Mildred Scheel Cancer Career Center HaTriCS4, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; ³Experimental Dermatology, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany; ⁴Institute for Advanced Simulation (IAS-2), Forschungszentrum Jülich, Jülich, Germany; ⁵Fleur Hiege Center for Skin Cancer Research, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; ⁶Pharmaceutical Institute, University of Bonn, Bonn, Germany; ⁷Neurology Department, Experimental Research in Stroke and Inflammation (ERSI), University Medical Center Hamburg-Eppendorf, Hamburg, Germany

  ICTHIC 2026

  16-04-2026

  https://doi.org/10.4081/btvb.2026.497

  496

  PDF: 108

• CO059 | EXTRACELLULAR VESICLES AS BIOMARKERS IN FAMILIAL HYPERCHOLESTEROLEMIAS TREATED WITH EVINACUMAB C. Samà¹, A. Benetti¹, M.G. Lupo², M. Biolo¹, C. Portinari¹, S. Zambon¹, A. Zambon¹, N. Ferri², C.M. Radu¹, P. Simioni¹ | ¹First Chair of Internal Medicine and Thrombotic and Haemorrhagic Diseases Unit, Department of Medicine, Padova University Hospital, Padova, Italy; ²Department of Medicine, Padova University Hospital, Padova, Italy

  Chiara Sama'

  26-10-2026

  https://doi.org/10.4081/btvb.2026.761

  21

  PDF: 10
• 

  Mechanistic insights into cancer-associated thrombosis in brain cancer

  Janusz Rak

  16-04-2026

  https://doi.org/10.4081/btvb.2026.430

  352

  PDF: 146
• 

  PO18 | THE THROMBO-INFLAMMATION AXIS AS PREDICTOR OF TOXICITY IN PATIENTS TREATED WITH CAR-T CELLS C. Fernández-Arias¹, M. Marcos-Jubilar¹, M. Panizo¹, C. Vázquez-Puerta², J.R. González-Porras², M. Ibáñez¹, A. Queralt¹, M. Carrasco¹, M.B. Villacrés¹, C. Conde¹, P. Elizalde¹, S. Huerga¹, A. Alfonso¹, P. Rodríguez-Otero¹, S. Villar¹, M.A. Canales¹, J. Rifón¹, F. Prósper¹, J.A. Páramo¹, J. Orbe¹, R. Lecumberri¹ | ¹Clínica Universidad de Navarra, Pamplona; ²Hospital Clínico Universitario de Salamanca, Salamanca, Spain

  ICTHIC 2026

  16-04-2026

  https://doi.org/10.4081/btvb.2026.513

  527

  PDF: 89

• CO077 | PLATELET MIR-144-5P REGULATES COX-1/2 EXPRESSION AND MODULATES ASPIRIN RESPONSE IN PATIENTS WITH CARDIOMETABOLIC RISK P. Simeone¹, R. Liani¹, V. Abbonante², M. Alfonsetti¹, M. Frezza¹, P. Lanuti¹, A. Recchiuti³, A. Balduini², F. Santilli¹ | ¹Department of Medicine and Aging, and Center for Advanced Studies and Technology (CAST), "G. d'Annunzio" University of Chieti-Pescara, Chieti, Italy; ²Department of Molecular Medicine, University of Pavia, Pavia, Italy; ³Department of Medical, Oral, and Biotechnological Science, Center for Advanced Studies and Technology (CAST), "G. d'Annunzio" University of Chieti-Pescara, Chieti, Italy

  Paola Giustina Maria Simeone

  26-10-2026

  https://doi.org/10.4081/btvb.2026.779

  23

  PDF: 8

• PO020 | EXTRACELLULAR VESICLE PROFILES REFLECT THROMBO-INFLAMMATORY ACTIVATION AND ARE ASSOCIATED WITH CLINICAL OUTCOMES IN LIVER CIRRHOSIS E. Campello^1|3, S. Toffanin^1|3, A. Zanetto^2|3, F. Kymentie^2|3, C. Bulato^1|3, B. Serena^1|3, C. Radu^1|3, P. Burra^2|3, F.P. Russo^2|3, L. Fabris^1|3, M. Senzolo^2|3, P. Simioni^1|3 | ¹Department of Medicine; ²Gastroenterology Unit; ³University of Padova, Italy

  Elena Campello

  26-10-2026

  https://doi.org/10.4081/btvb.2026.836

  21

  PDF: 9

• PO027 | IGFBP-6 REGULATES PLATELET PROCOAGULANT ACTIVITY AT THE INTERFACE BETWEEN INFLAMMATION AND COAGULATION L. Bury¹, E. Falcinelli¹, E. Petito¹, L. Leijonancker², H. van Ooijen², S. Petkov², A.R.D. Coda³, C. Raucci¹, V. Fazzi¹, D. Sarnà¹, C. Becattini¹, P. Gresele¹, A. Liso⁴ | ¹Department of Medicine and Surgery, Section of Internal and Cardiovascular Medicine, University of Perugia, Perugia, Italy; ²Pixelgen Technologies AB, Stockholm, Sweden; ³C.R.E.A.T.E.-Center for Research and Innovation in Medicine, Department of Medical and Surgical Sciences, University of Foggia, Italy; ⁴Department of Medicine and Surgery, University of Perugia, Perugia and Hematology/Oncology Unit, Terni Hospital, Terni, Italy

  Loredana Bury

  26-10-2026

  https://doi.org/10.4081/btvb.2026.843

  19

  PDF: 8

• PO019 | LONGITUDINAL COAGULATION PROFILING BY THROMBIN GENERATION AND CIRCULATING MICROVESISCLES OF INDIVIDUALS UNDERGOING GENDER-AFFIRMING HORMONE THERAPY E. Campello, A. Scala, A. Napolitano, C. Simion, C. Bulato, S. Toffanin, S. Gavasso, B. Serena, A. Montagna, A. Garolla, P. Simioni | Department of Medicine, University of Padova, Italy

  Elena Campello

  26-10-2026

  https://doi.org/10.4081/btvb.2026.835

  26

  PDF: 9
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  PO03 | HEPATIC FIBROSIS–DRIVEN TISSUE FACTOR EXPRESSION BY MALIGNANT CHOLANGIOCYTES IS ASSOCIATED WITH CANCER-ASSOCIATED THROMBOSIS AND POOR SURVIVAL IN INTRAHEPATIC CHOLANGIOCARCINOMA L. Fabris^1|2|3, Y. Frión-Herrera¹, C. Venturin^1|3, M. Cadamuro⁴, J. Gasparello⁵, C. M. Radu^1|2, M. Fassan^1|5, C. Mescoli⁶, U. Cillo^7|8, E. Gringeri^7|8, G. Zanus^7|9, E. Campello^1|2, M. Strazzabosco³, P. Simioni^1|2 | ¹Department of Medicine, University of Padua; ²Clinical Medicine 1 and Thrombotic and Haemorrhagic Disease Unit, and Haemophilia Center, Padua University-Hospital; ³Department of Internal Medicine, Digestive Disease Section, Liver Center, Yale University, New Haven, CT, USA; ⁴School of Medicine and Surgery, University of Milan-Bicocca, Milan, Italy; ⁵Pathology Unit, Ca' Foncello Hospital, ULSS2 Marca Trevigiana, Treviso; ⁶Pathology Unit, Padua University-Hospital; ⁷Department of Surgery, Oncology and Gastroenterology, University of Padua; ⁸Hepatobiliary Surgery and Liver Transplantation Unit, Padua University-Hospital; ⁹General Surgery Unit, Ca' Foncello Hospital, ULSS2 Marca Trevigiana, Treviso, Italy

  ICTHIC 2026

  16-04-2026

  https://doi.org/10.4081/btvb.2026.499

  522

  PDF: 99

• CO02 | Hepatic fibrosis as predictor of cancer-associated thrombosis in patients with intrahepatic cholangiocarcinoma Y. Frion-Herrera^1,2, C. Venturin^1,3, M. Cadamuro⁴, J. Gasparello⁵, C.M. Radu¹, M. Fassan⁵, C. Mescoli⁶, U. Cillo⁷, E. Gringeri⁷, G. Zanus⁸, L. Fabris^1,3, P. Simioni¹ | ¹Clinical Medicine and Thrombotic and Haemorrhagic Disease Unit, and Haemophilia Center, Padua University-Hospital, Department of Medicine [DIMED], University of Padua, Italy; ²Department of Biology [DiBio], University of Padua, Italy; ³Department of Internal Medicine, Digestive Disease Section, Liver Center, Yale University, New Haven, CT, USA; ⁴School of Medicine and Surgery, University of Milan-Bicocca, Milan, Italy; ⁵Department of Pathology Ca’ Foncello Hospital, ULSS2 Marca Trevigiana, Italy; ⁶Pathology Unit, Padua University-Hospital, Padua, Italy; ⁷Hepatobiliary Surgery and Liver Transplantation Unit, Padua University-Hospital, Department of Surgery, Oncology and Gastroenterology [DISCOG], University of Padua, Italy; ⁸General Surgery Unit, Ca’ Foncello Hospital, ULSS2 Marca Trevigiana, Department of Surgery, Oncology and Gastroenterology [DISCOG], University of Padua, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.207

  719

  PDF: 26
• 

  PO02 | SYNERGISTIC INTERACTION OF ENDOTHELIAL AND CANCER CELLS IN THE FORMATION AND STRUCTURE OF THE FIBRIN CLOT SHIELDS M.A. Baghdadi^1|2, E. Mbemba¹, P. Las Casa¹, P. Van Dreden^1|3, N. Saleem^1|4, J. Fareed⁴, P. Kempaiah⁴, M. Sabbah¹, G. Gerotziafas^1|4 | ¹Sorbonne University, INSERM UMR_S_938, CRSA, Research Department "Cancer, Vessels, Biology and Therapeutics" (CaVITE), Research Group "Cancer-Angiogenesis-Thrombosis and Haemostasis," Thrombosis Center, University Institute of Cancerology (UIC), Saint Antoine University Hospital Assistance Publique Hôpitaux de Paris (AP-HP) Paris France; ²Research Center, King Faisal Specialist Hospital and Research Center, Jeddah, Saudi Arabia; ³Diagnostica Stago, clinical research, Gennevilliers, France; ⁴Center of Translational Research and Education, Department of Pathology and Laboratory Medicine, Loyola University Stritch School of Medicine, Maywood, Ill., USA

  ICTHIC 2026

  16-04-2026

  https://doi.org/10.4081/btvb.2026.498

  464

  PDF: 99

• CO069 | POLYSTYRENE NANOPLASTICS PRIME PLATELET TO DRIVE PRO-INFLAMMATORY AND PRO-FIBROTIC ACTIVATION OF CARDIAC FIBROBLASTS Z. Saeed^1|2, M. Dovizio^1|3, C. Milillo^1|3, P. Lanuti^1|4, S. Porro^1|4, F. D’Ascanio^1|4, A. Bruno^1|3, P. Ballerini^1|3, G. Renda^1|2 | ¹Center for Advanced Studies and Technology (CAST), “G. d’Annunzio” University of Chieti-Pescara, Chieti, Italy; ²Department of Neurosciences, Imaging and Clinical Sciences, "G. d'Annunzio" University of Chieti-Pescara, Chieti, Italy; ³Department of Innovative Technologies in Medicine & Dentistry, “G. d’Annunzio” University of Chieti-Pescara, Chieti, Italy; ⁴Department of Medicine and Aging Sciences, “G. d’Annunzio” University of Chieti-Pescara, Chieti, Italy

  Zeeba Saeed

  26-10-2026

  https://doi.org/10.4081/btvb.2026.771

  23

  PDF: 11

• CO113 | AN OBSERVATIONAL STUDY ON THE EFFECT OF HEMODIALYSIS MEMBRANES ON ENDOGENOUS THROMBIN POTENTIAL IN END-STAGE RENAL DISEASE PATIENTS Z. Saeed^1|4, O. Ndrecka², V. Sirolli², M. Bonomini², P. Lanuti^1|3, S. Gallina⁴, G. Rend^1|4 | ¹Center for Advanced Studies and Technology, G. d’Annunzio University of Chieti-Pescara, Chieti, Italy; ²Nephrology and Dialysis Unit, Department of Medicine, G. d’Annunzio University of Chieti-Pescara, SS. Annunziata Hospital, Chieti, Italy; ³Department of Medicine and Aging Sciences, G. d’Annunzio University of Chieti-Pescara, Chieti, Italy; ⁴Department of Neuroscience, Imaging and Clinical Sciences, G. d’Annunzio University of Chieti-Pescara, Chieti, Italy

  Zeeba Saeed

  26-10-2026

  https://doi.org/10.4081/btvb.2026.815

  23

  PDF: 7
• 

  Are platelets more than a model of brain neurons?

  Ilaria Canobbio, Silvia Stella Barbieri

  12-05-2022

  https://doi.org/10.4081/btvb.2022.29

  1055

  PDF: 514