Thrombophilia work-up and clinical outcomes in Indian patients with unprovoked venous and arterial thrombosis aged 18-50 years

Harimadhavan, Monisha; Ram, Bharath; G, Karthick R; Shetty, Devi Prasad; Prabhu, Shilpa; S, Nataraj K; Nayak, Akshatha; Damodar, Sharat; Zanon, Ezio; Castaman, Giancarlo; Federici, Augusto Bramante; Mancuso, Maria Elisa; Pasut, Gianfranco; Tosetto, Alberto; Rocino, Angiola; Santoro, Rita Carlotta; Barcellona, Doris; Tripodi, Armando; Di Castelnuovo, Augusto; Persichillo, Mariarosaria; Candura, Fabio; Marchesini, Emanuela; Forni, Gian Luca; Gringeri, Alessandro; Gentilini, Ilaria; Tricoli, Mirko; Najjar, Osama; Teofili, Luciana

doi:10.4081/btvb..193

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PO29 | Quality of anticoagulation as a predictor of early left ventricular thrombosis resolution: a retrospective cohort study A. Pannunzio¹, I.M. Palumbo¹, M.P. Donadini², D. Santagata², W. Ageno², F. Dragoni³, A. Chistolini³, C. Becattini⁴, K. Satula⁴, D. Menichelli¹, D. Pastori¹, P. Pignatelli⁵, E. Valeriani¹ | ¹Department of General Surgery and Surgical Specialty Paride Stefanini, Sapienza University of Roma; ²Department of Medicine and Surgery, University of Insubria, Varese; ³Hematology, Department of Translational and Precision Medicine, Sapienza University of Roma; ⁴Internal Vascular and Emergency Medicine - Stroke Unit, University of Perugia; ⁵Department of Clinical Internal, Anesthesiological and Cardiovascular Sciences, Sapienza University of Roma, Italy

22-10-2025

https://doi.org/10.4081/btvb.2025.290

614

PDF: 18
CO20 | Coagulation alterations as prognostic indicators in septic patients L. Baratti¹, S. N. Pasturenzi¹, P. Onorato², W. Ageno³, F. Cortellaro², M.P. Donadini^2,4 | ¹Scuola di Medicina, Università degli Studi dell’Insubria, Varese; ²Pronto Soccorso e Medicina d’Urgenza, Ospedale di Circolo, Varese; ³Dipartimento di Medicina, Università degli Studi di Padova; ⁴Dipartimento di Medicina e Chirurgia, Università degli Studi dell’Insubria, Varese, Italy

22-10-2025

https://doi.org/10.4081/btvb.2025.226

651

PDF: 21
CO03 | Early discharge and home treatment of low-risk pulmonary embolism: a cohort study E. Ruggeri¹, L. Vulcano¹, W. Ageno², F. Cortellaro³, M.P. Donadini^3,4 | ¹Scuola di Medicina, Università degli Studi dell’Insubria, Varese; ²Dipartimento di Medicina, Università degli Studi di Padova; ³Pronto Soccorso e Medicina d’Urgenza, Ospedale di Circolo, ASST Sette Laghi, Varese; ⁴Dipartimento di Medicina e Chirurgia, Università degli Studi dell’Insubria, Varese, Italy

22-10-2025

https://doi.org/10.4081/btvb.2025.208

676

PDF: 31
CO01 | Statin therapy for the prevention of venous thromboembolism in cancer patients: a systematic review and meta-analysis F. Catalani, R. Del Giorno, R. Canevascini, W. Ageno, L. Gabutti, G. Prouse, L. Giovannacci | Ospedale Regionale di Bellinzona, Switzerland.

22-10-2025

https://doi.org/10.4081/btvb.2025.199

709

PDF: 19
CO015 | EVOLUTION OF ANTICOAGULANT THERAPY FOR CANCER-ASSOCIATED THROMBOSIS: THE START2 REGISTRY ONCO-VTE LONGITUDINAL STUDY M. Marchetti^1|2, T. Zollner^1|2, O.C. Cretu^1|2, A. Chistolini³, R. Pancani⁴, L. Puccetti⁵, P. Sivera⁶, W. Ageno⁷, G. Elmi⁸, V. Fregoni⁹, V. Tonelli¹⁰, E. Antonucci¹¹, D. Poli^11|12, A. Falanga^1|2, L. Barcella^1|2 | ¹Hemostasis & Thrombosis Center, Department of Transfusion Medicine, Papa Giovanni XXIII Hospital, Bergamo, Italy; ²ERN EuroBloodNet; ³Hematology Unit, Department of Translational and Precision Medicine, Sapienza University of Roma, Roma, Italy; ⁴Pulmonary Unit, Hospital of Siena, University of Siena, Siena, Italy; ⁵Hemostasis and Thrombosis Unit, Hospital of Siena, University of Siena, Siena, Italy; ⁶Haematology Unit, Ordine Mauriziano Hospital, Torino, Italy; ⁷Department of Medicine, University of Padua, Padova, Italy; ⁸Department of Medicine, Maggiore Hospital, Bologna, Italy; ⁹Department of Medicine, Sondalo Hospital, Sondalo, Italy; ¹⁰Angiology Unit, Sant'Eugenio Hospital, Roma, Italy; ¹¹Arianna Anticoagulazione Foundation, Bologna, Italy; ¹²Department of Critical Care Medicine, Thrombosis Centre, Azienda Ospedaliera Universitaria Careggi, Firenze, Italy

Marina Marchetti

26-10-2026

https://doi.org/10.4081/btvb.2026.717

143

PDF: 16
Aspirin or low-molecular weight heparin for thromboprophylaxis after a fracture? That is the question

Giuseppe Camporese, Paolo Prandoni, Walter Ageno

17-05-2023

https://doi.org/10.4081/btvb.2023.82

1497

PDF: 734
PO098 | REAL-WORLD EMERGENCY DEPARTMENT USE OF ANDEXANET ALFA FOR FACTOR XA INHIBITOR REVERSAL: AN ITALIAN COHORT M.P. Donadini^1|2, R. Brivio¹, S. Bozzato², L.M. Caiano², L. Galli², L. Bertù¹, F. Cortellaro², W. Ageno³ | ¹University of Insubria, Varese, Italy; ²ASST Sette Laghi, Varese, Italy; ³University of Padua, Padova, Italy

Marco Paolo Donadini

26-10-2026

https://doi.org/10.4081/btvb.2026.914

45

PDF: 16
CO012 | LONG-TERM RISK OF RECURRENT VENOUS THROMBOEMBOLISM IN ADULT PATIENTS WITH ACTIVE CANCER AND FIRST CATHETER-RELATED UPPER EXTREMITY DEEP VEIN THROMBOSIS AFTER DISCONTINUATION OF ANTICOAGULANT TREATMENTS AND LINE REMOVAL: A RETROSPECTIVE MULTI-CENTER COHORT STUDY – CANCER-CRT STUDY L. Girardi^1|2, W. Ageno³, L. Bertù¹, C. Lodigiani⁴, L.A. Ciuffini⁴, M.C. Vedovati⁵, C. Becattini⁵, A. Sammarco⁶, G. Camporese⁶, G. Cuni^1|7, C. Ambaglio⁷, M.P. Donadini¹ | ¹Research Center on Thromboembolic Diseases and Antithrombotic Treatment, Department of Medicine and Surgery, University of Insubria, Varese, Italy; ²Department of Medicine, The Ottawa Hospital Research Institute, University of Ottawa, Ontario, Canada; ³Department of Medicine, University of Padua, Padova, Italy; ⁴Center for Thrombosis and Hemorrhagic Diseases, IRCCS Humanitas Research Hospital, Rozzano, Milano, Italy; ⁵Internal and Cardiovascular Medicine-Stroke Unit, University of Perugia, Perugia, Italy; ⁶Clinica Medica 1, Department of Medicine, DIMED, Padova University Hospital, Padova, Italy; ⁷Immunohematology and Transfusion Medicine, Department of Transfusion Medicine and Hematology, ASST Papa Giovanni XXIII, Bergamo, Italy

Laura Girardi

26-10-2026

https://doi.org/10.4081/btvb.2026.714

136

PDF: 17
Milvexian and other drugs targeting Factor XI: a new era of anticoagulation?

Marco P. Donadini, Walter Ageno

15-04-2022

https://doi.org/10.4081/btvb.2022.22

2536

PDF: 773
PO094 | ARTIFICIAL INTELLIGENCE IN PULMONARY EMBOLISM PHENOTYPING: A SCOPING REVIEW D. Santagata¹, A. Abenante¹, S. Cosci², D. Steiner³, S. Nopp³, A. Squizzato¹, M.P. Donadini¹, F. Dentali¹, C. Ay³, W. Ageno⁴ | ¹Department of Medicine and Surgery, University of Insubria, Varese and Como, Italy; ²Department of Internal Medicine, Ente Ospedaliero Cantonale (EOC), Bellinzona, Switzerland; ³Clinical Division of Haematology and Haemostaseology, Department of Medicine I, Comprehensive Cancer Center Vienna, Medical University of Vienna, Vienna, Austria; ⁴Department of Medicine, University of Padova, Padova, Italy

Davide Santagata

26-10-2026

https://doi.org/10.4081/btvb.2026.910

46

PDF: 16
CO008 | ALLOSTATIC LOAD AND THE RISK OF ARTERIAL AND VENOUS VASCULAR EVENTS: A PROSPECTIVE ANALYSIS FROM THE MOLI-SANI STUDY T. Panzera¹, A. Di Castelnuovo¹, M. Bonaccio¹, S. Magnacca¹, A. De Curtis¹, F. Bracone¹, W. Ageno², C. Cerletti¹, M.B. Donati¹, G. de Gaetano¹, L. Iacoviello^1|3, S. Costanzo^1|4 | ¹Research Unit of Epidemiology and Prevention, IRCCS NEUROMED, Pozzilli, Italy; ²Department of Medicine, University of Padua, Padova, Italy; ³Department of Medicine and Surgery LUM University “Giuseppe Degennaro”, Casamassima, Italy; ⁴Department of Medicine and Surgery, University of Insubria, Varese, Italy

Teresa Panzera

26-10-2026

https://doi.org/10.4081/btvb.2026.710

122

PDF: 20
Rationale and design of a study on D-dimer use to stratify patients after a first unprovoked venous thromboembolism for their risk of recurrence: extended low-dose Apixaban given only to patients with positive D-dimer results The Apidulcis study

Gualtiero Palareti, Paolo Prandoni, Cristina Legnani, Emilia Antonucci, Serena Zorzi, Alberto Tosetto, Lorenza Bertù, Sophie Testa, Vittorio Pengo, Walter Ageno, Ida Martinelli, Benilde Cosmi, Eugenio Bucherini, Daniela Poli

22-03-2022

https://doi.org/10.4081/btvb.2022.10

1894

PDF: 569

APPENDIX: 144
PO006 | FLOW-MEDIATED DILATION AND ECFC DERIVED ENDOTHELIAL DYSFUNCTION IN VENOUS THROMBOEMBOLISM C.M. Totè¹, M. Donadini^1|2, R. Ciceri^3|4, M. Bacci⁴, A. Cancellara^3|4, E. Romualdi¹, L. Guerrieri^3|4, F. Tumminello⁴, C. Lodigiani⁴, W. Ageno⁵, S. Della Bella^3|4, F. Calcaterra^3|4, D. Mavilio^3|4 | ¹ASST Sette Laghi, Varese, Italy; ²Università of Insubria, Varese, Italy; ³University of Milano, Milano, Italy; ⁴IRCCS Humanitas Research Hospital, Rozzano, Italy; ⁵Università of Padua, Padova, Italy

Chiara Maria TotÈ

26-10-2026

https://doi.org/10.4081/btvb.2026.822

31

PDF: 14
Expanding the genetic landscape of hereditary thrombophilia: classical defects, novel variants, and genomic perspectives. A narrative review

Chiara Simion, Elena Campello, Walter Ageno, Paolo Simioni

28-08-2026

https://doi.org/10.4081/btvb.2026.427

1236

PDF: 158

SUPPLEMENTARY FILES: 110
PO001 | EMERGENCY DEPARTMENT MANAGEMENT OF PULMONARY EMBOLISM IN CANCER PATIENTS: PROGNOSTIC STRATIFICATION AND OUTCOMES A. Decursu¹, L. Galli², LM. Caiano², S. Bozzato², E. Ruggeri¹, F. Paletta³, L. Vulcano¹, L. Bertù¹, F. Cortellaro², W. Ageno⁴, MP. Donadini^1|2 | ¹Università degli studi dell'Insubria, Italy; ²ASST Sette Laghi, Italy; ³Università degli studi di Milano-Bicocca, Italy; ⁴Università degli studi di Padova, Italy

Alessandro Decursu

26-10-2026

https://doi.org/10.4081/btvb.2026.817

32

PDF: 12
PO25 | EVOLUTION OF ANTICOAGULANT STRATEGIES AND CLINICAL OUTCOMES IN CANCER-ASSOCIATED THROMBOSIS: A LONGITUDINAL ANALYSIS OF THE START2 REGISTRY ONCO-VTE M. Marchetti^1|2, T. Zollner^1|2, OC. Cretu^1|2, A. Chistolini³, R. Pancani⁴, L. Puccetti⁵, P. Sivera⁶, W. Ageno⁷, G. Elmi⁸, V. Fregoni⁹, V. Tonelli¹⁰, E. Antonucci¹¹, D. Poli^11|12, A. Falanga^1|2, L. Barcella^1|2 | ¹Hemostasis & Thrombosis Center, Department of Transfusion Medicine, Papa Giovanni XXIII Hospital, Bergamo Italy; ²ERN EuroBloodNet; ³Hematology Unit, Department of Translational and Precision Medicine, Sapienza University of Rome, Rome, Italy; ⁴Pulmonary Unit, Hospital of Siena, University of Siena, Siena, Italy; ⁵Hemostasis and Thrombosis Unit, Hospital of Siena, University of Siena, Siena, Italy; ⁶Haematology Unit, Ordine Mauriziano Hospital, Turin, Italy; ⁷Department of Medicine, University of Padua, Padua, Italy; ⁸Department of Medicine, Maggiore Hospital, Bologna, Italy; ⁹Department of Medicine, Sondalo Hospital, Sondalo, Italy; ¹⁰Angiology Unit, Sant'Eugenio Hospital, Rome, Italy; ¹¹Arianna Anticoagulazione Foundation, Bologna, Italy; ¹²Department of Critical Care Medicine, Thrombosis Centre, Azienda Ospedaliera Universitaria Careggi, Firenze, Italy

ICTHIC 2026

16-04-2026

https://doi.org/10.4081/btvb.2026.520

444

PDF: 92
CO111 | ROLE OF CONSTITUTIVE ENDOTHELIAL DYSFUNCTION IN THE PATHOGENESIS OF UNPROVOKED VENOUS THROMBOEMBOLISM: CHARACTERIZATION OF ENDOTHELIAL COLONY-FORMING CELLS AND ASSOCIATION WITH RISK OF RECURRENCE F. Calcaterra^1|2, R. Ciceri^1|2, M. Bacci¹, A. Cancellara^1|2, E. Romualdi³, L. Guerrieri^1|2, F. Tumminello¹, C. Lodigiani¹, W. Ageno⁴, S. Della Bella^1|2, D. Mavilio^1|2, M.P. Donadini^3|5 | ¹IRCCS Humanitas Research Hospital, Italy; ²University of Milano, Italy; ³ASST Sette Laghi, Varese, Italy; ⁴University of Padua, Padova, Italy; ⁵University of Insubria, Varese, Italy

Marco Paolo Donadini

26-10-2026

https://doi.org/10.4081/btvb.2026.813

53

PDF: 17
The role of dyslipidemia and gender-related risk factors in the management of patients with abdominal aortic aneurysms: a survey from the Italian Society of Angiology and Vascular Medicine and a call to action

Martina Berteotti, Walter Ageno, Rossella Marcucci, Andrea Stella, Paolo Zamboni, Romeo Martini

30-06-2025

https://doi.org/10.4081/btvb.2025.164

1429

PDF: 351
Executive summary of the consensus-based guidance from the SISET (Italian Society for the Study of Hemostasis and Thrombosis) for the management of inferior vena cava thrombosis

Luca Barcella, Simona Pedrini, Luca Sarti, Monia Marchetti, Claudio Sallemi, Antonella Tufano, Walter Ageno, Marco Marietta

16-10-2026

https://doi.org/10.4081/btvb.2026.582

272

PDF: 42
The therapeutic landscape of cancer-associated splanchnic vein thrombosis

Alessia Abenante, Filippo Catalani, Walter Ageno

16-04-2026

https://doi.org/10.4081/btvb.2026.458

326

PDF: 155
CO054 | ULTRA-PROCESSED FOOD CONSUMPTION IS ASSOCIATED WITH AN INCREASED RISK OF UNPROVOKED VENOUS THROMBOEMBOLISM IN THE MOLI-SANI STUDY M. Bonaccio¹, A. Di Castelnuovo¹, S. Costanzo^1|2, T. Panzera¹, C. Cerletti¹, MB. Donati¹, G. de Gaetano¹, W. Ageno³, L. Iacoviello^1|4 | ¹Research Unit of Epidemiology and Prevention, IRCCS NEUROMED, Pozzilli (IS), Italy; ²Dep. of Medicine and Surgery, University of Insubria, Varese, Italy; ³Dep. of Medicine, Università degli Studi di Padova, Padova, Italy; ⁴Dep. of Medicine and Surgery LUM University, Casamassima (BA), Italy

Marialaura Bonaccio

26-10-2026

https://doi.org/10.4081/btvb.2026.756

40

PDF: 19
Management of anticoagulation in atrial fibrillation patients in Italy: insight from the Atrial Fibrillation-Survey on Anticoagulated Patients Register (AF-START)

Daniela Poli, Walter Ageno, Emilia Antonucci, Salvatore Bradamante, Eugenio Bucherini, Paolo Chiarugi, Antonio Chistolini, Benilde Cosmi, Anna Falanga, Antonio Insana, Domenico Lione, Rosa Maria Lombardi, Giuseppe Malcangi, Rossella Marcucci, Giuliana Martini, Lucilla Masciocco, Carmelo Paparo, Daniele Pastori, Simona Pedrini, Vittorio Pengo, Pasquale Pignatelli, Andrea Toma, Sophie Testa, Gualtiero Palareti

27-06-2023

https://doi.org/10.4081/btvb.2023.84

2169

PDF: 651

Supplementary File: 290
PO138 | THE START-SIAPAV-PAD REGISTRY: RATIONALE, STUDY DESIGN AND BASELINE CHARACTERISTICS OF AN ITALIAN MULTICENTRE REGISTRY E. Favaretto¹, A. Visonà², C. Amato³, F. Biscetti^4|5, B. Zalunardo⁶, F. Ghirardini⁷, A. Porfidia⁸, M. Cini⁹, E. Antonucci⁹, W. Ageno¹⁰ | ¹Angiology Unit, IRCCS azienda ospedaliero-universitaria di Bologna, Italy; ²Osp Riabilitativo di Alta Specializzazione (ORAS), Treviso, Italy; ³Angiology Unit, University of Palermo, Italy; ⁴Dep of Translational Medicine and Surgery, Catholic University of the Sacred Heart, Roma, Italy; ⁵UOC of Cardiovascular Internal Medicine, A. Gemelli, Roma, Italy; ⁶Angiology Unit, Azienda ULSS 2 Marca Trevigiana, Castelfranco Veneto, Treviso, Italy; ⁷Angiology Unit, Azienda ULSS 1 Dolomiti, Belluno, Italy; ⁸Dep of Geriatric, Orthopedic, and Rheumatologic Sciences, A. Gemelli IRCCS University Hospital Foundation, Roma, Italy; ⁹Fondazione Arianna Anticoagulazione, Bologna, Italy; ¹⁰Dep of Medicine, University of Padua, Italy

Elisabetta Favaretto

26-10-2026

https://doi.org/10.4081/btvb.2026.954

39

PDF: 16
Executive summary of the SISET position paper on the management of antithrombotic therapy in left ventricular thrombus

Emanuele Valeriani, Arianna Pannunzio, Danilo Menichelli, Domenico Prisco, Walter Ageno, Daniele Pastori, Pasquale Pignatelli

16-12-2025

https://doi.org/10.4081/btvb.2025.401

479

PDF: 141

HTML: 113

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CO01 | Statin therapy for the prevention of venous thromboembolism in cancer patients: a systematic review and meta-analysis F. Catalani, R. Del Giorno, R. Canevascini, W. Ageno, L. Gabutti, G. Prouse, L. Giovannacci | Ospedale Regionale di Bellinzona, Switzerland.

Aspirin or low-molecular weight heparin for thromboprophylaxis after a fracture? That is the question

Milvexian and other drugs targeting Factor XI: a new era of anticoagulation?

Rationale and design of a study on D-dimer use to stratify patients after a first unprovoked venous thromboembolism for their risk of recurrence: extended low-dose Apixaban given only to patients with positive D-dimer results The Apidulcis study

Expanding the genetic landscape of hereditary thrombophilia: classical defects, novel variants, and genomic perspectives. A narrative review

The role of dyslipidemia and gender-related risk factors in the management of patients with abdominal aortic aneurysms: a survey from the Italian Society of Angiology and Vascular Medicine and a call to action

Executive summary of the consensus-based guidance from the SISET (Italian Society for the Study of Hemostasis and Thrombosis) for the management of inferior vena cava thrombosis

The therapeutic landscape of cancer-associated splanchnic vein thrombosis

Management of anticoagulation in atrial fibrillation patients in Italy: insight from the Atrial Fibrillation-Survey on Anticoagulated Patients Register (AF-START)

Executive summary of the SISET position paper on the management of antithrombotic therapy in left ventricular thrombus

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