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• PO75 | Prophylaxis with RFXIII: a clinical case in a pediatric patient with congenital FXIII deficiency and delayed diagnosis M.L. Tramontano, M. Coppola, S. Coppola, M. Schiavulli | UOSD Centro Regionale Pediatrico Malattie della Coagulazione. Santobono Pausilipon Children Hospital, AORN, Napoli, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.344

  665

  PDF: 37

• PO55 | Evaluation of safety and efficacy of emicizumab prophylaxis in pediatric patients with hemophilia A – a single centre experience M.L. Tramontano, M. Coppola, S. Coppola, M. Schiavulli | UOSD Centro Regionale Pediatrico Malattie della Coagulazione, Santobono Pausilipon Children Hospital, AORN, Napoli, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.324

  579

  PDF: 28

• CO-50 | LEFT ATRIAL APPENDAGE OCCLUSION IN PATIENTS WITH ATRIAL FIBRILLATION AND BLEEDING DISORDERS: A SINGLE-CENTER EXPERIENCE B.M. Roccon¹, M.I. Tassoni¹, G. Quintavalle¹, G. Benatti², F. Gurgoglione², R. Rossi³, C. Cattabiani³, L. Vignali², A. Tagliaferri¹, A. Coppola¹ | ¹SSD Centro Hub Emofilia e Malattie Emorragiche Congenite, Azienda Ospedaliero-Universitaria di Parma, Italy; ²SSD Cardiologia Interventistica, Azienda Ospedaliero-Universitaria di Parma, Italy; ³Laboratorio di Coagulazione, UOC Patologia Clinica, Azienda Ospedaliero-Universitaria di Parma, Italy

  Antonio Coppola

  14-10-2026

  https://doi.org/10.4081/btvb.2026.660

  68

  PDF: 21

• PO126 | HIGH-DOSE INTRAVENOUS IMMUNOGLOBULINS FOR LONG-TERM PREVENTION OF RECURRENT GASTROINTESTINAL BLEEDING IN A PATIENT WITH ACQUIRED VON WILLEBRAND SYNDROME ASSOCIATED WITH MGUS R. Benedetti¹, G. Quintavalle², V. Della Corte¹, M.I. Tassoni¹, B.M. Roccon¹, D. Imberti¹, A. Coppola² | ¹Centro Emostasi e Trombosi, Medicina Interna, Azienda USL di Piacenza, Italy; ²SSD Centro Hub Emofilia e Malattie Emorragiche Congenite, Azienda Ospedaliero-Universitaria di Parma, Italy

  Antonio Coppola

  26-10-2026

  https://doi.org/10.4081/btvb.2026.942

  32

  PDF: 11

• PO044 | UPDATING MANAGEMENT OF ACQUIRED HEMOPHILIA A USING EMICIZUMAB: REAL-WORLD OUTCOMES BY A COLLABORATIVE NETWORK OF 3 ITALIAN CENTERS MI. Tassoni¹, BM. Roccon¹, A. Dalla Salda², R. Benedetti³, R. Rossi⁴, C. Cattabiani⁴, G. Quintavalle¹, A. Casali², D. Imberti³, A. Coppola¹ | ¹SSD Centro Hub Emofilia e Malattie Emorragiche Congenite, Azienda Ospedaliero-Universitaria di Parma, Italy; ²SOC Medicina Interna per acuti ad indirizzo metabolico ed emocoagulativo, Azienda USL IRCCS Reggio Emilia, Italy; ³Centro Emostasi e Trombosi, Medicina Interna, Azienda USL Piacenza, Italy; ⁴Lab. di Coagulazione, UOC Diagnostica Ematochimica, Azienda Ospedaliero-Universitaria di Parma, Italy

  Antonio Coppola

  26-10-2026

  https://doi.org/10.4081/btvb.2026.860

  30

  PDF: 13

• PO14 | Searching for safer rescue immunosuppressive therapy protocols in acquired hemophilia A: two case reports G. Quintavalle¹, I.M. Tassoni¹, B.M. Roccon¹, G. Lucchini², F. Magalini², M. Zardo², R. Rossi³, C. Cattabiani³, A. Tagliaferri¹, A. Coppola¹ | ¹SSD Centro HUB Emofilia e MEC; ²UOS Medicina Interna e Reumatologia; ³UO Diagnostica Ematochimica, Azienda Ospedaliero Universitaria, Parma, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.275

  560

  PDF: 30

• PO002 | VENOUS THROMBOEMBOLISM IN PATIENTS WITH FACTOR VII DEFICIENCY: A CASE SERIES AND REVIEW OF THE LITERATURE BM. Roccon¹, MI. Tassoni¹, G. Quintavalle¹, F. Riccardi¹, A. Matichecchia¹, GF. Rivolta¹, M. Lombardi³, R. Rossi², A. Benegiamo², A. Tagliaferri¹, A. Coppola¹ | ¹SSD Centro Hub Emofilia e Malattie Emorragiche Congenite, Azienda Ospedaliero-Universitaria di Parma, Italy; ²Lab. di Coagulazione, UOC Diagnostica Ematochimica, Azienda Ospedaliero-Universitaria di Parma, Italy; ³Centro Emostasi, UOC Medicina Interna ad indirizzo angiologico e coagulativo, Azienda Ospedaliero-Universitaria di Parma, Italy

  Antonio Coppola

  26-10-2026

  https://doi.org/10.4081/btvb.2026.818

  42

  PDF: 16

• CO27 | Intracerebral hemorrhage in hemophilia A and B: a 10-year prospective multicenter study in Italy (2012–2022) E. Zanon¹, A. Napolitano¹, A. Porreca², F. Demartis³, A. Coppola⁴, C. Santoro⁵, I. Cantori⁶, A. C. Molinari⁷, C. Biasioli⁸, M. Luciani⁹, G. Sottilotta¹⁰, B. Pollio¹¹, A. Borchiellini¹², A. Tosetto¹³, P. Flora¹⁴, P. Simioni¹ | ¹Haemophilia Center, First Chair of Internal Medicine, Department of Medicine, University-Hospital of Padua Medical School, Padua; ²Department of Human Sciences and Promotion of the Quality of Life, Unit of Clinical and Molecular Epidemiology IRCCS San Raffaele Roma Open University, Roma; Unit of Clinical and Molecular Epidemiology IRCCS San Raffaele, Roma; ³Centre for Bleeding Disorders, Careggi University Hospital of Firenze; ⁴Azienda Ospedaliero Universitaria di Parma; ⁵Hematology Division, Umberto I University Hospital of Roma; ⁶Haemophilia Center, Department of Transfusion Medicine, Hospital of Macerata; ⁷IRCCS Istituto Giannina Gaslini, Genova; ⁸Haemophilia and Transfusion Centre, Bufalini Hospital, Cesena; ⁹Children’s Hospital Bambino Gesù, Roma; ¹⁰Haemophilia Center, Department of Onco-Hematology and Radioterapy, Hospital of Reggio Calabria; ¹¹Haemophilia Pediatric Center, Transfusion Medicine, City of Health and Science of Turin; ¹²City of Health and Science of Turin; ¹³Hemorrhagic and Thrombotic Diseases Unit, S. Bortolo Hospital of Vicenza; ¹⁴RCCS Foundation Ca’ Granda Maggiore Policlinico Hospital, Milan, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.233

  701

  PDF: 37

• CO-61 | REAL-WORLD IMPLEMENTATION OF GENE THERAPY FOR HEMOPHILIA: A SHARED PATHWAY AMONG HEALTHCARE AUTHORITY, SPECIALIST CENTERS AND PATIENT ORGANIZATIONS IN THE EMILIA-ROMAGNA REGION A. Coppola¹, L. Valdrè², C. Biasoli³, E. Ferri Grazzi⁴, E. Rozzi⁵, M. Volta⁵, R. Giroldini⁶, A. Tagliaferri¹ | ¹SSD Centro Hub Emofilia e Malattie Emorragiche Congenite, Azienda Ospedaliero-Universitaria di Parma, Italy; ²SSD Malattie Emorragiche Congenite, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Italy; ³SSI Presa in Carico delle Malattie Emorragiche e Tromboemboliche, AUSL Romagna, Ospedale Bufalini, Cesena, Italy; ⁴FEDRED, Federazione delle Associazioni Emofilici della Regione Emilia Romagna, Italy; ⁵Servizio Assistenza Ospedaliera, Malattie Rare, Direzione Generale Cura della Persona, Salute e Welfare, Regione Emilia Romagna, Italy; ⁶Area Governo del Farmaco e Dispositivi Medici, Direzione Generale Cura della Persona, Salute e Welfare, Regione Emilia Romagna, Italy

  Antonio Coppola

  14-10-2026

  https://doi.org/10.4081/btvb.2026.671

  57

  PDF: 15

• CO-60 | A TURNING POINT IN THE MANAGEMENT OF HEMOPHILIA B WITH INHIBITORS: OUTCOMES OF CONCIZUMAB PROPHYLAXIS IN TWO CHILDREN FROM EXPLORER10 G. Quintavalle¹, A. Matichecchia¹, M.I. Tassoni¹, B.M. Roccon¹, F. Riccardi¹, R.P. Serra², A. Tiri², P. Bertolini², A. Tagliaferri¹, A. Coppola¹ | ¹Regional Hub Center for Hemophilia and Congenital Bleeding Disorders, University Hospital of Parma, Italy; ²Pediatric Hematology-Oncology Unit, University Hospital of Parma, Italy

  Antonio Coppola

  14-10-2026

  https://doi.org/10.4081/btvb.2026.670

  60

  PDF: 18
• 

  The landscape of rare coagulation factor deficiency management in Italy: a national hemophilia center survey

  Silvia Linari, Renato Marino, Marzia Leotta, Antonio Coppola, Patrizia Di Gregorio, Augusto Bramante Federici, Flora Peyvandi, Cristina Santoro, Ezio Zanon, Rita Carlotta Santoro

  05-11-2025

  https://doi.org/10.4081/btvb.2025.369

  1365

  PDF: 221

  HTML: 136

  Appendix: 120

• CO-49 | JOINT STATUS EVALUATION BY ULTRASOUND AND FUNCTIONAL ASSESSMENT IN PERSONS WITH NON SEVERE HEMOPHILIA ON PROPHYLAXIS WITH FOCUS ON THOSE WITH 5-YR FOLLOW UP G. Quintavalle¹, M.I. Tassoni¹, B.M. Roccon¹, G.F. Rivolta¹, C. Costantino², R.M. Polo³, A. Matichecchia¹, A. Tagliaferri¹, A. Coppola¹ | ¹SSD Centro Hub Emofilia e Malattie Emorragiche Congenite, Az. Ospedaliero-Universitaria di Parma, Italy; ²SSD Riabilitazione Ambulatoriale e Ortogeriatrica, Az. Ospedaliero-Universitaria di Parma, Italy; ³Clinica Ortopedica, Az. Ospedaliero-Universitaria di Parma, Italy

  Gabriele Quintavalle

  14-10-2026

  https://doi.org/10.4081/btvb.2026.659

  54

  PDF: 16

• CO-22 | CLINICAL FEATURES IN PATIENTS WITH NON-SEVERE HEMOPHILIA A: THE DISCOVERY SCORE PROPOSAL FOR PROPHYLAXIS PRESCRIPTION M.N.D. Di Minno¹, E. Baldacci², C. Biasoli³, A. Borchiellini⁴, F. Daniele⁵, P. Di Gregorio⁶, C. Gorio⁷, G. Malcangi⁸, E. Marchesini⁹, I. Ricca¹⁰, R. Santoro¹¹, S. Siragusa¹², M.R. Villa¹³, E. Zanon¹⁴, A. Tagliaferri¹⁵, A. Coppola¹⁵ | ¹Hub Centre for Thrombotic and Hemorrhagic Disorders, Federico II University Hospital, Napoli, Italy; ²Haematology, University Hospital Policlinico Umberto I, Roma, Italy; ³Interdepartmental Simple Structure for the Management of Hemorrhagic and Thromboembolic Diseases, M. Bufalini Hospital, Cesena, Italy; ⁴Regional Centre for Hemorrhagic and Thrombotic Diseases, AOU Città della Salute e della Scienza, Torino, Italy; ⁵Haemostasis and Thrombosis Service, Ospedale Civile dell'Annunziata, Cosenza, Italy; ⁶Transfusion Medicine Department, "SS. Annunziata" Hospital, Chieti, Italy; ⁷Pediatric Onco-Hematology Unit, Children's Hospital, ASST-Spedali Civili, Brescia, Italy; ⁸Haemophilia and Thrombosis Center, University Hospital Policlinico-Giovanni XXIII, Bari, Italy; ⁹Hemophilia Centre, SC Vascular and Emergency Department, University of Perugia, Italy; ¹⁰Centro Emofilia, Città della Salute e della Scienza, Torino, Italy; ¹¹Hemostasis and Thrombosis Unit, Azienda Ospedaliero Universitaria Dulbecco, Catanzaro, Italy; ¹²Centro di Riferimento Regionale per le Emocoagulopatie Congenite, Palermo, Italy; ¹³Hematology Unit, Ospedale Santa Maria di Loreto, Napoli, Italy; ¹⁴Hemophilia and Thrombosis Center, University Hospital of Padua, Italy; ¹⁵Hemophilia and Thrombosis Center, Azienda Ospedaliera di Parma, Italy

  Matteo Di Minno

  14-10-2026

  https://doi.org/10.4081/btvb.2026.632

  73

  PDF: 18

• PO041 | VARIABLE CLINICAL RESPONSE TO RECOMBINANT PORCINE FVIII IN ACQUIRED HAEMOPHILIA A: A TWO CASE EXPERIENCE WITH LABORATORY SUPPORTED MONITORING AM. Pizzini¹, M. Bovara², M. Sebastiani², A. Fusco¹, C. Fantoni¹, M. Silingardi¹, R. Mancini², A. Coppola³ | ¹Ambulatorio Emostasi & Trombosi, Dipartimento Medico - Ospedale Maggiore Bologna, Italy; ²Laboratorio Unico Metropolitano - Ospedale Maggiore Bologna, Italy; ³SDD Centro Hub Emofilia e MEC, Azienda Ospedaliero-Universitaria di Parma, Italy

  Attilia Maria Pizzini

  26-10-2026

  https://doi.org/10.4081/btvb.2026.857

  38

  PDF: 14

• CO-03 | BEYOND CONVENTIONAL TESTING: NANOPORE LONG-READ SEQUENCING FOR RECURRENT F8 INVERSIONS IN HEMOPHILIA A A. Taiani^1|2, F. Riccardi¹, L. Cozzuto⁴, A. Delgado⁴, S. Busciglio^1|2, G. Quintavalle¹, A. Matichecchia¹, I. Tassoni¹, B.M. Roccon¹, I. R. Cannizzaro², A. Luberto², J. Ponomarenko⁴, A. Percesepe³, V. Barili², A. Coppola¹ | ¹Regional Hub Center for Hemophilia and Congenital Bleeding Disorders, University Hospital of Parma, Italy; ²Medical Genetics, Department of Medicine and Surgery, University of Parma, Italy; ³Medical Genetics, University Hospital of Parma, Italy; ⁴Centre Genomic Regulation, CRG, Barcelona, Spain

  Antonietta Taiani

  14-10-2026

  https://doi.org/10.4081/btvb.2026.613

  144

  PDF: 17
• 

  Bioequivalence of von Willebrand factor-containing concentrates: implications for the choice in patients with von Willebrand disease. A position paper from the Italian Association of Hemophilia Centers

  Ezio Zanon, Giancarlo Castaman, Augusto Bramante Federici, Maria Elisa Mancuso, Gianfranco Pasut, Alberto Tosetto, Angiola Rocino, Rita Carlotta Santoro

  26-01-2026

  https://doi.org/10.4081/btvb.2026.415

  1312

  PDF: 348

  HTML: 165
• 

  Iatrogenic pseudoaneurysm of inferior epigastric artery: not only a surgical complication

  Rossana Corso, Andrea Coppola, Stefano Grazioli, Cristina Dedionigi, Nicolò Tandurella, Massimo Venturini, Francesco Dentali

  14-07-2022

  https://doi.org/10.4081/btvb.2022.25

  1152

  PDF: 399

  Supplementary Video: 341
• 

  Diagnostic and management practices for inherited fibrinogen disorders: a nationwide survey of Italian Hemophilia Treatment Centers

  Renato Marino, Silvia Linari, Marzia Leotta, Antonio Coppola, Chiara Biasoli, Maria Elisa Mancuso, Flora Peyvandi, Cristina Santoro, Ezio Zanon, Rita Carlotta Santoro

  02-12-2025

  https://doi.org/10.4081/btvb.2025.372

  931

  PDF: 121

  HTML: 129

  Supplementary: 79

  Appendix: 80