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• CS01 | Elucidating the evil relationship of metabolic dysfunction–associated fatty liver disease with cardiovascular comorbidities: the complex interplay among hypercoagulability, inflammation and liver fibrosis G. Gagliardi, E. Campello, A. Napolitano, B. Stocco, C. Di Gesù, G. Gobbo, I. Condonato, M. Allegra, G. Camporese, P. Scarinzi, R. Pesavento, F. Bilora, C. Bulato, A. Benetti, C. Samà, C. Portinari, G. Antonello, C. Goffi, L. Di Daniel, A. Zambon, L. Fabris, P. Simioni | First Chair of Internal Medicine, Department of Medicine, University-Hospital of Padua Medical School, Padua, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.196

  467

  PDF: 0

• CO14 | Inflammation and fibrinolysis biomarkers as predictors of cancer risk in healthy subjects: results from the hypercan study C. Ticozzi¹, S. Bolognini^1,2, P. Gomez-Rosas^1,3, L. Russo^1,2, Cj. Tartari^1,2, F. Schieppati^1,2, G. Sampietro⁴, L. Barcella¹, M. Marchetti^1,2, A. Falanga^1,2 | ¹Immunohematology and Transfusion Medicine, Hospital Papa Giovanni XXIII, Bergamo, Italy; ²School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy; ³Maastricht University Medical Center, Cardiovascular Research Institute Maastricht, Maastricht, The Netherlands; ⁴Unit of Epidemiology and Statistics, ATS Bergamo, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.218

  347

  PDF: 0

• CO25 | Thromboinflammation and ros accumulation in individuals with high lipoprotein(a) levels M. Frezza¹, P.G.M. Simeone¹, M. Alfonsetti¹, R. Liani¹, M. Cellini¹, P. Del Boccio², M.C. Cufaro³, O. Iuliani⁴, A. Quaglietta⁴, F. Cipollone¹, F. Santilli¹ | ¹Department of Medicine and Ageing Sciences, Center for Advanced Studies and Technology “CAST”, University of Chieti; ²Department of Pharmacy, Center for Advanced Studies and Technology “CAST”, Chieti; ³Department of Innovative Technologies in Medicine and Dentistry, Center for Advanced Studies and Technology “CAST”, Chieti; ⁴Department of Haematolgy and Oncology, Center of Transfusion Medicine, Pescara General Hospital, Pescara. Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.231

  342

  PDF: 0

• CO23 | Markers of inflammation and hypofibrinolysis are associated with cognitive dysfunction and motor performances in atrial fibrillation patients on oral anticoagulant therapy: insights from the Strat-AF study F. Alfano^1,2, F. Cesari^1,2, A.M. Gori^1,2, M. Berteotti^1,2, E. Salvadori³, B. Giusti^1,2, A. Bertelli^1,2, F. Fratini⁴, A. Rogolino^1,2, B. Formelli^4,5, F. Pescini^4,5, E. Fainardi⁶, E. Barucci⁴, G. Salti⁵, A. Cavaliere⁴, A. Ginestroni⁶, A. Poggesi^4,5, R. Marcucci^1,2 | ¹Department of Experimental and Clinical Medicine, University of Firenze; ²Center for Atherothrombotic Diseases, Careggi University Hospital, Firenze; ³Department of Biomedical and Clinical Sciences, University of Milan; ⁴NEUROFARBA Department, Neuroscience Section, University of Firenze; ⁵Stroke Unit, Careggi University Hospital, Firenze; ⁶Neuroradiology Unit, Careggi University Hospital, Department of Experimental and Clinical Biomedical Sciences, University of Firenze, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.229

  354

  PDF: 0

• PO26 | Non-canonical coagulation platelets function: monocyte-platelet interaction a bridge between inflammation and coagulation A. Benetti¹, A. Galbiati¹, M. Cola², L. Calandrino², C. Samà¹, D. Regazzo¹, S. Ferrari¹, C.M. Radu¹, A. Cattelan², P. Simioni¹ | ¹Department of Medicine - DIMED; ²Infectious and Tropical Diseases Unit, Padua University Hospital, Padua, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.287

  311

  PDF: 0

• PO11 | Neutrophil cathepsin G and risk of cardiovascular events in patients with diabetes mellitus V. Cammisotto¹, F. Baratta², S. Bartimoccia³, D. Pastori¹, N. Cocomello⁴, V. Castellani⁵, C. Nocella¹, R. Carnevale³, G. Desideri¹, F. Violi¹, P. Pignatelli¹ | ¹Department of Clinical, Internal Medicine, Anesthesiological and Cardiovascular Sciences, Sapienza University of Roma; ²Geriatric Unit, Department of Internal Medicine and Medical Specialties, AOU Policlinico Umberto I, Roma; ³Department of Medical-Surgical Sciences and Biotechnologies, Sapienza University of Roma; ⁴Department of Anatomical Sciences, Histological, Legal Medical and Locomotor, Sapienza University of Roma; ⁵Department of Experimental Medicine, Sapienza University of Roma, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.273

  317

  PDF: 0

• PO82 | Retrospective application of the TH2 score in a multicenter cohort of ITP patients: a reliable predictive tool or a score in need of refinement? C. Giubbilei¹, M. Defina², S. Rosati³, M. Rocco³, A. Votto⁴, F. Simonetti⁵, F. Paoletti⁶, V. Carrai¹ | ¹Hematology Unit, AOU Careggi; ²Hematology unit AOU Senese; ³Hematology Unit Azienda Sanitaria Toscana Centro; ⁴Hematology Unit, AOU Pisana; ⁵Hematology Unit, Ospedale Versilia; ⁶Hematology Unit, Azienda Sanitaria Nord Ovest, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.351

  355

  PDF: 0

• PO56 | Safety of anticoagulant treatment in patients with splanchnic vein thrombosis and history of portal hypertension-related bleeding R. Talerico¹, S. Pellegrino¹, A. Plessier², F.R. Ponziani³, A. Porfidia¹, F. Landi¹, A. Gasbarrini³, R. Pola¹, F. Santopaolo³ | ¹Department of Geriatric, Orthopedic, and Rheumatologic Sciences, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Roma, Italy; ²Université de Paris, AP-HP, C, DMU DIGEST, Centre de Référence des Maladies Vasculaires du Foie, FILFOIE, ERN RARE-LIVE. Centre de recherche sur l’inflammation, Inserm, Paris, France; ³Department of Medical and Surgical Sciences, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Roma, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.325

  302

  PDF: 0

• PO54 | Resolvin response in bronchial asthma patients: endotype and clinical severity R. Liani¹, I. Altomare², P.G.M. Simeone¹, M. Alfonsetti¹, M. Mucci³, D. Madonna¹, S. Lattanzio¹, A. Ricci⁴, A.M. Draicchio², A. De Sanctis², P. Di Mattia², F. Papa², E. Cavallucci², F. Cipollone¹, A. Recchiuti³, F. Santilli¹ | ¹Department of Medicine and Aging, and Center for Advanced Studies and Technology “CAST”, G. d’Annunzio University of Chieti-Pescara, Chieti; ²Allergy and Immunology Section, Department Internal Medicine, G. d’Annunzio University, School of Medicine, Chieti; ³Department of Medical, Oral and Biotechnological Sciences, and Center for Advanced Studies and Technology “CAST”, G. d’Annunzio University, Chieti-Pescara; ⁴Department of Pharmacy, University G. d’Annunzio of Chieti Pescara, Chieti, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.323

  299

  PDF: 0

• CO24 | Extracellular vesicles profiles in patients with wild-type transthyretin amyloidosis S. Toffanin¹, L. Spiezia¹, C.M. Radu¹, A. Napolitano¹, A. Benetti¹, C. Samà¹, E. Campello¹, L. De Michieli², G. Sinigiani², A. Cipriani², P. Simioni¹ | ¹First Chair of Internal Medicine, Department of Medicine, University-Hospital of Padua Medical School, Padua; ²Department of Cardiac, Thoracic and Vascular Sciences and Public Health, University of Padua, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.230

  325

  PDF: 0

• PO33 | Whole blood hypercoagulable profiles in patients with rheumatoid arthritis L. Spiezia¹, A. Giollo², C. Samà¹, A. Benetti¹, L. Di Luozzo², M. Salvato², A. Doria², P. Simioni¹ | ¹First Chair of Internal Medicine, Thrombotic and Hemorrhagic Diseases Unit, Department of Medicine, University Hospital of Padova; ²Rheumatology Unit, Department of Medicine, University Hospital of Padova, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.296

  301

  PDF: 0

• PO91 | Disseminated intravascular coagulation with deep vein thrombosis in a frail patient: an extreme manifestation triggered by sepsis during SGLT2i therapy M. Vacca¹, M.V. Cherchi¹, S. Che¹, G.A.M.L. Costanzo², D. Firinu², M. Mantega¹, S. Del Giacco² | ¹Ospedale Sirai, ASL Sulcis, ²Università degli Studi di Cagliari, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.361

  394

  PDF: 0

• PO88 | Bacterial lysate “lantigen B” induces proliferation of B and NK cells and the release of related cytokines M. Alfonsetti¹, R. Liani¹, P. Di Mattia³, M. Tredicine⁴, F. Papa³, Q. Niu⁵, M. Di Gioacchino², F. Santilli^1,3 | ¹Department of Medicine and Aging, Center for Advanced Studies and Technology, University of Chieti, Italy; ²Institute for Clinical Immunotherapy and Advanced Biological Treatments, Pescara, Italy; ³Specialization School of Allergy and Clinical Immunology, G. d’Annunzio University, Chieti, Italy; ⁴Department of Medical, Oral, and Biotechnology Science, University G. d’Annunzio, Chieti-Pescara, Chieti, Italy; ⁵Department of Occupational Health, School of Public Health, Shanxi Medical University, Taiyuan, Shanxi, China

  22-10-2025

  https://doi.org/10.4081/btvb.2025.358

  374

  PDF: 0

• PO06 | Extracellular vesicles profiles in patients with porto-sinusoidal vascular disease S. Toffanin¹, E. Campello¹, A. Zanetto², C. M. Radu¹, E. Pinto², K. Fernande², C. Bulato¹, B. Serena¹, L. Spiezia¹, P. Burra², M. Senzolo², P. Simioni¹ | ¹First Chair of Internal Medicine, Department of Medicine, University Hospital of Padua Medical School, Padua; ²Department of Surgery Oncology and Gastroenterology, Gastroenterology and Multivisceral Transplant Unit, University Hospital of Padua, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.268

  310

  PDF: 0

• PO76 | Thrombosis associated with midline in autoimmune patient: a case report on the use of apixaban in a real-world setting M.V. Cherchi, M. Anedda, S. Che, M. Vacca, M. Caboni, M. Mantega | Department of Internal Medicine, ASL Sulcis, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.345

  330

  PDF: 0

• CO43 | Early platelet dysfunction in sepsis: an ICU pilot study S. Sorrentino¹, C. Gori², L. D’Innocenzo¹, M. De Siati¹, Mg. Bocci³, E. De Candia¹ | ¹Unit of Haemostasis and Thrombosis Diseases, Fondazione Policlinico Universitario A. Gemelli, IRCCS, Roma; ²UOC Shock & Trauma, Azienda Ospedaliera San Camillo Forlanini, Roma; ³National Institute for Infectious Diseases, Lazzaro Spallanzani, IRCCS, Roma, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.249

  314

  PDF: 0

• PO92 | Challenging management of portal vein thrombosis in a cirrhotic patient on hormone therapy after breast cancer L. Jr Valletta, C. De Luca, M. Aversano, C. Caputo, E. Cimino, P. Conca, A. Tufano, M.D. Di Minno | AOU Federico II Napoli, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.362

  364

  PDF: 0