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• 29th National Conference of the Italian Society for the Study of Hemostasis and Thrombosis, 2025

  Guest Editor: Valerio De Stefano

  22-10-2025

  https://doi.org/10.4081/btvb.2025.408

  460

• CO19 | Hypercoagulability in wild-type transthyretin amyloidosis: evidence from whole blood thromboelastometry A. Napolitano¹, L. Spiezia¹, C. Samà¹, A. Benetti¹, G. Sinigiani², L. De Michieli², A. Cipriani², P. Simioni¹ | ¹First Chair of Internal Medicine, Department of Medicine, University Hospital of Padua; ²Department of Cardiothoracic and Vascular Sciences & Public Health, University Hospital of Padua, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.223

  311

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• CO46 | Comparison of reticulated platelet procoagulant role in liver cirrhosis vs. fibrosis S. Toffanin¹, E. Campello¹, A. Zanetto², G. Gagliardi¹, A. Napolitano¹, E. Stocco¹, G. Gobbo¹, E. Pinto², C. M. Radu¹, M. Senzolo², L. Fabris¹, P. Simioni¹ | ¹First Chair of Internal Medicine, Department of Medicine, University-Hospital of Padua Medical School, Padova; ²Department of Surgery Oncology and Gastroenterology, Gastroenterology and Multivisceral Transplant Unit, Padova University Hospital, Padova, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.256

  292

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• CS07 | Endothelial dysfunction and impaired angiogenesis in Hermansky-Pudlak syndrome (HPS) type 1: studies with endothelial colony forming cells F. Tondi¹, G. Purgatorio¹, C. Sgromo², E. Giglio¹, E. Petito¹, E. Falcinelli¹, G. Guglielmini¹, A. Follenzi², P. Gresele¹, L. Bury^1*, C. Olgasi^3* | ^*Shared senior authorship; ¹Department of Medicine and Surgery, Section of Internal and Cardiovascular Medicine, University of Perugia; ²Department of Health Sciences, School of Medicine, University of Piemonte Orientale, Novara; ³Department of Translational Medicine, School of Medicine, University of Piemonte Orientale, Novara, Italy

  16-09-2025

  https://doi.org/10.4081/btvb.2025.204

  151

• PO13 | Monitoring of anti-factor XA activity levels in patients treated with direct oral anticoagulants and concomitant tyrosine kinase inhibitors agents: a monocentric experience E. Santacroce^1,2, C. Santoro¹, E. Baldacci¹, S. Ligia¹, R. Mormile¹, M. Biglietto¹, M. Totaro¹, F. R. Mauro¹, M. Breccia¹, A. Chistolini¹ | ¹Department of Translational and Precision Medicine, Haematology, Sapienza University of Roma; ²Department of Clinical and Molecular Medicine, Sapienza University of Roma, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.313

  320

  PDF: 0

• CO08 | The utility of urine qualitative assessment for direct oral anticoagulants in routine clinical practice F. Schieppati^1,2, P. Gomez-Rosas^1,3, C. Ambaglio¹, V. Brusegan¹, Oc. Cretu^1,2, E. Galimberti¹, F. Zunino¹, L. Barcella¹, J. Harenberg^4,5, A. Falanga^1,2, M. Marchetti^1,2 | ¹Immunohematology and Transfusion Medicine, Hospital Papa Giovanni XXIII, Bergamo, Italy; ²School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy; ³Maastricht University Medical Center, Cardiovascular Research Institute Maastricht, Maastricht, The Netherlands; ⁴Ruprecht Karls University of Heidelberg, Germany; ⁵Germany DOASENSE GmbH, Heidelberg, Germany

  22-10-2025

  https://doi.org/10.4081/btvb.2025.212

  383

  PDF: 0

• CO44 | First interlaboratory validation workshop of immunofluorescence microscopy on the peripheral blood smear for recognizing patients with inherited platelet disorders C. Zaninetti¹, L. Bury², V. Bozzi³, A. Zamora-Cánovas⁴, K. Althaus⁵, G. Uzun⁵, S. Brown⁶, A. Norman⁶, D. Faille⁷, A. Stepanian⁸, C. Freyer¹, L. Kager⁹, T. Bakchoul⁵, A. Pecci³, P. Gresele², T. Thiele¹, J. Rivera⁴, A. Greinacher¹ | ¹Institut für Immunologie und Transfusionsmedizin, Universitätsmedizin Greifswald, Germany; ²Department of Medicine, Section of Internal and Cardiovascular Medicine, University of Perugia, Italy; ³Department of Internal Medicine, University of Pavia, Italy; General Medicine 1, IRCCS Policlinico San Matteo Foundation, Pavia, Italy; ⁴Servicio de Hematología, Hospital Universitario Morales Meseguer, Centro Regional de Hemodonacio´n, Universidad de Murcia, Spain; ⁵Institute for Clinical and Experimental Transfusion Medicine, University Hospital of Tuebingen, Germany; Center for Clinical Transfusion Medicine, Tuebingen, Germany; ⁶Centre for Children’s Health and Research CCHR, South Brisbane, Australia; ⁷Laboratoire d’Hématologie, Assistance Publique Hôpitaux de Paris, Hôpital Bichat-Claude-Bernard, Paris, France; ⁸AP-HP, Service d’Hématologie Biologique, Hôpital Lariboisière, Paris Cité University, Paris, France; ⁹St. Anna Kinderspital, Universitätsklinik für Kinder- und Jugendheilkunde der Medizinischen Universität Wien, Austria

  22-10-2025

  https://doi.org/10.4081/btvb.2025.250

  301

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• PO02 | Pregnancy and delivery in women with hemophilia and carriers are still challenging: a ten years analysis from The Italian Association of Hemophilia Centers (AICE) M. Napolitano¹, M. Mattana², C. Cammarata¹, M. Leotta³, S. Linari⁴, M.E. Mancuso⁵, G. F. Rivolta⁶, C. Santoro⁷, L. Valdrè⁸, R.C. Santoro³, S. Siragusa¹ | ¹Department of Health Promotion, Mother and Child Care, Internal Medicine and Med, Palermo; University of Palermo, Italy; ²Department of Precision Medicine in Medical, Surgical and Critical Care “Me. Pre. Cc”, University of Palermo; ³Hemostasis and Thrombosis Unit, Azienda Ospedaliera Universitaria Dulbecco, Catanzaro; ⁴Center for Bleeding Disorders, Careggi University Hospital, Firenze; ⁵Center for Thrombosis and Hemorrhagic Diseases, IRCCS Humanitas Research Hospital, Rozzano, Milan; ⁶Regional Reference Center for the Treatment of Congenital Hemorrhagic Diseases, Parma University Hospital, Parma; ⁷Hematology, University Hospital Policlinico Umberto I, Roma; ⁸Inherited Bleeding Disorders Unit, IRCCS AOUBO, Bologna, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.312

  320

  PDF: 0

• CS04 | Association between elevated plasma levels of tissue plasminogen activator and occult cancer risk: a nested case-cohort analysis in 10,294 healthy subjects S. Bolognini^1,2, C. Ticozzi¹, P. Gomez-Rosas^1,3, L. Russo^1,2, Cj. Tartari^1,2, F. Schieppati^1,2, G. Sampietro⁴, L. Barcella¹, M. Marchetti^1,2, A. Falanga^1,2 | ¹Immunohematology and Transfusion Medicine, Hospital Papa Giovanni XXIII, Bergamo, Italy; ²School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy; ³Maastricht University Medical Center, Cardiovascular Research Institute Maastricht, The Netherlands; ⁴Unit of Epidemiology and Statistics, ATS Bergamo, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.201

  374

  PDF: 0

• CO39 | Artificial intelligence in hemophilia management: challenging the need for experts G. Sottilotta¹, D. Megalizzi¹, F. Luise² | ¹UOSD Microcitemie - Emostasi e Trombosi. Grande Ospedale Metropolitano Bianchi-Melacrino-Morelli, Reggio Calabria; ²Laboratorio Analisi, Grande Ospedale Metropolitano Bianchi-Melacrino-Morelli, Reggio Calabria, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.246

  305

  PDF: 0

• PO41 | Comparison of the haemorrhagic phenotype between female and male patients affected by autosomal inherited bleeding disorders in a single-centre cohort B. Borsellino^1,3, C. Zuccotti², L. Guarnera^3,4, C. Biasoli⁵, P. Pedrazzi⁵, T. Martini¹ | ¹Haemophilia Centre, Immune-Haematology and Transfusion Medicine, University Hospital “Città della Salute e della Scienza”, Turin, Italy; ²Department of Clinical Pathology, Bufalini Hospital, Cesena, Italy; ³Department of Biomedicine and Prevention, PhD in Immunology, Molecular Medicine and Applied Biotechnology, University of Roma Tor Vergata, Roma, Italy; ⁴Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH, USA; ⁵Haemophilia and Transfusion Centre, Bufalini Hospital, Cesena, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.304

  288

  PDF: 0

• CO24 | Extracellular vesicles profiles in patients with wild-type transthyretin amyloidosis S. Toffanin¹, L. Spiezia¹, C.M. Radu¹, A. Napolitano¹, A. Benetti¹, C. Samà¹, E. Campello¹, L. De Michieli², G. Sinigiani², A. Cipriani², P. Simioni¹ | ¹First Chair of Internal Medicine, Department of Medicine, University-Hospital of Padua Medical School, Padua; ²Department of Cardiac, Thoracic and Vascular Sciences and Public Health, University of Padua, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.230

  325

  PDF: 0

• PO38 | Rates of hemorrhagic events and hemodialysis circuit thrombosis in patients with end-stage renal disease on hemodialytic treatment receiving a factor-XI inhibitor: a systematic review and meta-analysis D. Santagata, G. Barbui, M.P. Donadini, A. Squizzato | Department of Medicine and Surgery, Research Center on Thromboembolic Disorders and Antithrombotic Therapies, University of Insubria, Varese and Como, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.301

  300

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• PO83 | A case of deep vein thrombosis in a patient with systemic mastocytosis M. Leotta, A. Ierardi, A. Strangio, R C. Santoro | UO Emofilia, Emostasi e Trombosi, AOU R Dulbecco, Catanzaro

  22-10-2025

  https://doi.org/10.4081/btvb.2025.352

  358

  PDF: 0

• PO21 | Exploring endothelial damage: the interplay between coagulopathy, capillary leak and vasoplegia in sepsis M. Facci¹, G. Turcato¹, A. Zaboli², L. Filippi¹, P. Ferretto¹, M. Maggi¹, F. Lucente¹, D. Milazzo¹, A. Bresolin¹, M. Marchetti¹ | ¹UOC Medicina Generale, Ospedale Alto Vicentino, Santorso, (VI); ²Innovation, Research and Teaching Service “SABES-ASDAA” of Azienda Sanitaria dell’Alto Adige, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.281

  291

  PDF: 0

• PO52 | Comprehensive assessment of variables affecting spontaneous platelet aggregation C. Ghali¹, A. Fioretti¹, M. Scavone¹, E. Bossi¹, B. Clerici¹, S. Birocchi¹, E. Popov², M. Centola³, G.M. Podda¹, M. Cattaneo⁴ | ¹Divisione di Medicina Generale II, ASST Santi Paolo e Carlo, DISS, Università degli Studi di Milano, Italy; ²National Medical Research Center of Cardiology, Ministry of Health of the Russian Federation, Moscow; ³Division of Cardiology, Pio XI Hospital, ASST Brianza, Desio, Italy; ⁴Fondazione Arianna Anticoagulazione, Bologna, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.321

  314

  PDF: 0

• CO16 | The predictive value of high-sensitivity C-reactive protein for assessing thrombosis risk in non-small cell lung cancer P. Gomez-Rosas^1,2, M. Marchetti^1,3, L. Russo¹, C.J. Tartari¹, S. Bolognini¹, C. Ticozzi¹, F. Schieppati¹, A. D’Alessio⁴, R. Labianca⁵, A. Falanga^1,3 All on behalf of the Hypercan Investigators | ¹Hospital Papa Giovanni XXIII, Bergamo, Italy; ²Cardiovascular Research Institute Maastricht, CARIM, Maastricht University, Maastricht, the Netherlands; ³School of Medicine and Surgery, University of Milan Bicocca, Italy; ⁴University Vita-Salute San Raffaele, Milan, Italy; ⁵Fondazione ARTET Onlus, Bergamo, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.220

  324

  PDF: 0

• PO15 | Venous thromboembolism risk associated with midline catheters and peripherally inserted central catheters: a systematic review and meta-analysis D. Santagata¹, F. Subri¹, F. Dentali^1,2, M.P. Donadini¹, I. Giarretta² | ¹Department of Medicine and Surgery, Research Center on Thromboembolic Disorders and Antithrombotic Therapies, University of Insubria, Varese and Como; ²Department of Internal Medicine, Ospedale di Circolo and Fondazione Macchi, Varese, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.276

  301

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• PO48 | Thrombotic risk evaluation and thrombophilia testing in β-thalassemia patients: a retrospective cohort analysis from a reference regional center G.M. Camarda^1,2*, S. Raso^1*, R. Di Maggio¹, M. Vinciguerra³, A. Giangreco¹, A. Inzerillo¹, A. Maggio, M. Napolitano^1,2 | ^*These authors contributed equally to this abstract; ¹Hematology and Rare Diseases Unit, Azienda Ospedaliera Ospedali Riuniti Villa Sofia-Cervello, Palermo; ²Division of Hematology Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties “ProMISE”, Palermo; ³UOSD Molecular Diagnosis of Rare Blood Diseases, Azienda Ospedaliera, Ospedali Riuniti Villa Sofia, Cervello, Palermo, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.317

  302

  PDF: 0

• CO14 | Inflammation and fibrinolysis biomarkers as predictors of cancer risk in healthy subjects: results from the hypercan study C. Ticozzi¹, S. Bolognini^1,2, P. Gomez-Rosas^1,3, L. Russo^1,2, Cj. Tartari^1,2, F. Schieppati^1,2, G. Sampietro⁴, L. Barcella¹, M. Marchetti^1,2, A. Falanga^1,2 | ¹Immunohematology and Transfusion Medicine, Hospital Papa Giovanni XXIII, Bergamo, Italy; ²School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy; ³Maastricht University Medical Center, Cardiovascular Research Institute Maastricht, Maastricht, The Netherlands; ⁴Unit of Epidemiology and Statistics, ATS Bergamo, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.218

  347

  PDF: 0