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• PO031 | IMBALANCE OF PLATELET PRODUCTION AND DESTRUCTION IN PREECLAMPSIA P. Simeone¹, R. Liani¹, M. Alfonsetti¹, A. Ricci¹, V. Cianci¹, L. Cantagallo¹, Z. Saeed², M. Molino³, S. Palma², R. Malizia⁴, M. Luongo⁴, A. Di Castelnuovo⁵, S. Gallina², F. Cipollone¹, F. Ricci², G. Renda², F. D’ Antonio⁶, F. Santilli¹ | ¹Department of Medicine and Aging Sciences, Center for Advanced Studies and Technology, G. d’Annunzio University of Chieti-Pescara, Chieti, Italy University General Medicine Division, Medical Department, SS. Annunziata Hospital, Chieti, Italy; ²Department of Neuroscience, Imaging and Clinical Sciences and Center for Advanced Studies and Technology, G. d'Annunzio University of Chieti-Pescara, Chieti, Italy University Cardiology Division, Heart Department, SS. Annunziata Hospital, Chieti, Italy; ³Clinical Pathology, SS. Annunziata Hospital, Chieti, Italy; ⁴Immunotransfusion Service, Clinical Haematology, SS. Annunziata Hospital, Chieti, Italy; ⁵Research Unit of Epidemiology and Prevention, IRCCS NEUROMED, Pozzilli (IS), Italy; ⁶Centre for Fetal Care and High-Risk Pregnancy, SS. Annunziata Hospital, Chieti, Italy

  Paola Giustina Maria Simeone

  26-10-2026

  https://doi.org/10.4081/btvb.2026.847

  50

  PDF: 26
• 

  Persistence of functional anti-PF4 antibodies and neutrophil activation in vaccine-induced immune thrombotic thrombocytopenia

  Eleonora Petito, Anna Maria Mezzasoma, Emanuela Falcinelli, Chiara Conti, Erica De Candia, Raimondo De Cristofaro, Silvia Sorrentino, Gian Marco Podda, Mariangela Scavone, Anna Falanga, Marina Marchetti, Luca Barcella, Stefania Basili, Lucia Stefanini, Andrea Boccatonda, Laura Contino, Patrizia Sciancalepore, Igor Florio, Egidio Imbalzano, Rossella Marcucci, Angela Rogolino, Patrizia Noris, Marta Panella, Rita Santoro, Maria Costanza Turi, Gaetano Vaudo, Rosa Curcio, Paolo Gresele

  18-11-2025

  https://doi.org/10.4081/btvb.2025.400

  976

  PDF: 182

  HTML: 207
• 

  The landscape of rare coagulation factor deficiency management in Italy: a national hemophilia center survey

  Silvia Linari, Renato Marino, Marzia Leotta, Antonio Coppola, Patrizia Di Gregorio, Augusto Bramante Federici, Flora Peyvandi, Cristina Santoro, Ezio Zanon, Rita Carlotta Santoro

  05-11-2025

  https://doi.org/10.4081/btvb.2025.369

  1370

  PDF: 221

  HTML: 137

  Appendix: 121

• PO60 | Asymptomatic PNH clone in acquired aplasia (AA) E. Marrone¹, U. Valentino¹, C. Mastrobuoni¹, A. Abate¹, A. Magliocca¹, F. Cinque¹, R. Buono¹, M. Annunziata², A. Picardi³, P. Morella¹ | ¹UOC Medicina 3, ²UOC Ematologia, ³UOC Ematologia, e Trapianto, AORN A. Cardarelli, Napoli, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.329

  585

  PDF: 23

• CO-22 | CLINICAL FEATURES IN PATIENTS WITH NON-SEVERE HEMOPHILIA A: THE DISCOVERY SCORE PROPOSAL FOR PROPHYLAXIS PRESCRIPTION M.N.D. Di Minno¹, E. Baldacci², C. Biasoli³, A. Borchiellini⁴, F. Daniele⁵, P. Di Gregorio⁶, C. Gorio⁷, G. Malcangi⁸, E. Marchesini⁹, I. Ricca¹⁰, R. Santoro¹¹, S. Siragusa¹², M.R. Villa¹³, E. Zanon¹⁴, A. Tagliaferri¹⁵, A. Coppola¹⁵ | ¹Hub Centre for Thrombotic and Hemorrhagic Disorders, Federico II University Hospital, Napoli, Italy; ²Haematology, University Hospital Policlinico Umberto I, Roma, Italy; ³Interdepartmental Simple Structure for the Management of Hemorrhagic and Thromboembolic Diseases, M. Bufalini Hospital, Cesena, Italy; ⁴Regional Centre for Hemorrhagic and Thrombotic Diseases, AOU Città della Salute e della Scienza, Torino, Italy; ⁵Haemostasis and Thrombosis Service, Ospedale Civile dell'Annunziata, Cosenza, Italy; ⁶Transfusion Medicine Department, "SS. Annunziata" Hospital, Chieti, Italy; ⁷Pediatric Onco-Hematology Unit, Children's Hospital, ASST-Spedali Civili, Brescia, Italy; ⁸Haemophilia and Thrombosis Center, University Hospital Policlinico-Giovanni XXIII, Bari, Italy; ⁹Hemophilia Centre, SC Vascular and Emergency Department, University of Perugia, Italy; ¹⁰Centro Emofilia, Città della Salute e della Scienza, Torino, Italy; ¹¹Hemostasis and Thrombosis Unit, Azienda Ospedaliero Universitaria Dulbecco, Catanzaro, Italy; ¹²Centro di Riferimento Regionale per le Emocoagulopatie Congenite, Palermo, Italy; ¹³Hematology Unit, Ospedale Santa Maria di Loreto, Napoli, Italy; ¹⁴Hemophilia and Thrombosis Center, University Hospital of Padua, Italy; ¹⁵Hemophilia and Thrombosis Center, Azienda Ospedaliera di Parma, Italy

  Matteo Di Minno

  14-10-2026

  https://doi.org/10.4081/btvb.2026.632

  76

  PDF: 19

• CO113 | AN OBSERVATIONAL STUDY ON THE EFFECT OF HEMODIALYSIS MEMBRANES ON ENDOGENOUS THROMBIN POTENTIAL IN END-STAGE RENAL DISEASE PATIENTS Z. Saeed^1|4, O. Ndrecka², V. Sirolli², M. Bonomini², P. Lanuti^1|3, S. Gallina⁴, G. Rend^1|4 | ¹Center for Advanced Studies and Technology, G. d’Annunzio University of Chieti-Pescara, Chieti, Italy; ²Nephrology and Dialysis Unit, Department of Medicine, G. d’Annunzio University of Chieti-Pescara, SS. Annunziata Hospital, Chieti, Italy; ³Department of Medicine and Aging Sciences, G. d’Annunzio University of Chieti-Pescara, Chieti, Italy; ⁴Department of Neuroscience, Imaging and Clinical Sciences, G. d’Annunzio University of Chieti-Pescara, Chieti, Italy

  Zeeba Saeed

  26-10-2026

  https://doi.org/10.4081/btvb.2026.815

  65

  PDF: 19

• CO057 | THROMBOPOIETIN-PLATELET AXIS IN METABOLIC-ASSOCIATED STEATOTIC LIVER DISEASE M. Alfonsetti¹, P. Simeone¹, R. Liani¹, M. Frezza¹, B. Di Marco¹, A. Cipollone¹, C. Della Penna¹, L. Cantagallo¹, G. Ciferni¹, L. Del Rosso¹, M. Caporale¹, S. Brandolino², E. Vitacolonna², P. Di Carlo³, F. Cipollone¹, F. Santilli¹ | ¹Department of Medicine and Aging Sciences, Center for Advanced Studies and Technology (CAST), University of Chieti, Chieti, Italy, University General Medicine Division, Medical Department, SS. Annunziata Hospital, Chieti, Italy; ²Department of Medicine and Aging, School of Medicine and Health Sciences, G. d'Annunzio University, Chieti, Italy; ³Department of Innovative Technologies in Medicine & Dentistry, "G. d'Annunzio" University of Chieti-Pescara, Chieti, Italy

  Paola Giustina Maria Simeone

  26-10-2026

  https://doi.org/10.4081/btvb.2026.759

  63

  PDF: 21

• CO056 | URINARY MARKERS OF PLATELET ACTIVATION AND OXIDATIVE STRESS IN ATHEROSCLEROTIC CARDIOVASCULAR DISEASE IN TYPE 2 DIABETES M. Alfonsetti¹, P. Simeone¹, R. Liani¹, M. Frezza¹, B. Di Marco¹, A. Cipollone¹, D. D’ Ardes¹, T. Taverriti¹, C. Della Penna¹, L. Cantagallo¹, G. Ciferni¹, L. Del Rosso¹, M. Caporale¹, S. Brandolino², E. Vitacolonna², P. Di Carlo³, F. Cipollone¹, F. Santilli¹ | ¹Department of Medicine and Aging Sciences, Center for Advanced Studies and Technology (CAST), University of Chieti, Chieti, Italy, University General Medicine Division, Medical Department, SS. Annunziata Hospital, Chieti, Italy; ²Department of Medicine and Aging, School of Medicine and Health Sciences, G. d'Annunzio University, Chieti, Italy; ³Department of Innovative Technologies in Medicine & Dentistry, "G. d'Annunzio" University of Chieti-Pescara, Chieti, Italy

  Paola Giustina Maria Simeone

  26-10-2026

  https://doi.org/10.4081/btvb.2026.758

  58

  PDF: 20

• PO32 | Effect of the sodium-glucose co-transporter-2 (SGLT2) inhibitors on platelet activation and lipid peroxidation: results of a pilot study P.G.M. Simeone¹, R. Liani¹, M. Alfonsetti¹, B. Cancelli¹, M. Frezza¹, G. Raggiunti¹, S. Zeeba², F. Cipollone¹, G. Renda², F. Santilli¹ | ¹Department of Medicine and Aging Sciences, Center for Advanced Studies and Technology, University of Chieti; ²Department of Neuroscience, Imaging and Clinical Sciences, G. D’Annunzio University of Chieti-Pescara; ³University Cardiology Division, Heart Department, Policlinico SS Annunziata, Chieti, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.293

  619

  PDF: 21

• CO001 | DERIVATION AND VALIDATION OF THE BLEEPE SCORE FOR RISK STRATIFICATION OF MAJOR BLEEDING IN PATIENTS WITH ACUTE PULMONARY EMBOLISM M. Vedovati¹, L. Cimini¹, V. Valeriano², I. Montenovo¹, A. Murgia³, L. Pierpaoli⁴, G. Tratar⁵, S. Zaccaroni⁶, A. Bongarzoni⁷, A. Vinci¹, A. Mavri⁵, L. Martinelli⁸, G. Pepe⁹, S. Cozzio¹⁰, C. Becattini¹ | ¹University of Perugia, Perugia, Italy; ²Sandro Pertini Hospital, Roma, Italy; ³SS. Annunziata Hospital, Sassari, Italy; ⁴S. Maria delle Croci Hospital, Ravenna, Italy; ⁵University Medical Centre Ljubljana, Ljubljana, Slovenia; ⁶Maggiore Hospital, Bologna, Italy; ⁷ASST Santi Paolo e Carlo-PO San Carlo, Milano, Italy; ⁸Città di Castello Hospital, Città di Castello, Italy; ⁹Versilia Hospital, Tuscany North West Health System, Lido di Camaiore (LU), Italy; ¹⁰Rovereto Hospital, Rovereto, Italy

  Maria Cristina Vedovati

  26-10-2026

  https://doi.org/10.4081/btvb.2026.703

  189

  PDF: 22

• CO45 | Role of urinary 11-dehydro-thromboxane B2 as a predictor of preeclampsia in pregnant high-risk women on low-dose aspirin treatment P.G.M. Simeone¹, R. Liani¹, M. Alfonsetti¹, A. Ricci¹, V. Cianci¹, S. Zeeba², M. Molino³, S. Palma², R. Malizia⁴, M. Luongo⁴, A. Di Castelnuovo⁵, F. Cipollone¹, F. D’antonio⁶, F. Ricci², G. Renda², F. Santilli¹ | ¹Department of Medicine and Aging Sciences, Center for Advanced Studies and Technology, University of Chieti; ²Department of Neuroscience, Imaging and Clinical Sciences, G D’Annunzio University of Chieti-Pescara, Chieti; University Cardiology Division, Heart Department, Policlinico SS Annunziata, Chieti; ³Clinical Pathology of Chieti University Hospital; ⁴Immunotransfusion Service, Clinical Haematology of Chieti University Hospital, Chieti; ⁵Mediterranea Cardiocentro, Napoli; ⁶Centre for Fetal Care and High-Risk Pregnancy, Department of Obstetrics and Gynecology, University of Chieti, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.251

  631

  PDF: 17

• PO145 | KINETIC ASSESSMENT OF PLATELET REACTIVITY DURING DUAL ANTIPLATELET THERAPY IN ACUTE CORONARY SYNDROMES: PRELIMINARY RESULTS FROM AN ONGOING STUDY B. Di Marco^1|2, R. Liani¹, F. D’Ambrosio^1|2, M. Alfonsetti¹, P.G. Simeone¹, M. Frezza¹, S. Porro¹, M. Brambilla³, P. Lanuti¹, M. Camera³, F. Santilli¹ | ¹Department of Medicine and Aging Sciences, Center for Advanced Studies and Technology (CAST), University of Chieti, Chieti, Italy; ²ASL 2 Abruzzo, SS. Annunziata Hospital, Chieti, Italy; ³Unit of Cell and Molecular Biology in Cardiovascular Diseases, Centro Cardiologico Monzino IRCCS, Milano, Italy

  Beatrice Di Marco

  26-10-2026

  https://doi.org/10.4081/btvb.2026.961

  54

  PDF: 21

• CO38 | Management of pregnancy, delivery, and postpartum in Italian carriers and women with hemophilia A and B S. Linari¹, B. Pollio², A. Ferretti³, M. Napolitano⁴, E. Grandone⁵, S. Siboni⁶, Ab. Aru⁷, E. Bertoni⁸, C. Biasoli⁹, I. Cantori¹⁰, P. Di Gregorio¹¹, G. Lassandro¹², G. Sottilotta¹³, A. Strangio¹⁴, Mr. Villa¹⁵, A. Rocino¹⁶, G. Castaman¹ | ¹Center for Bleeding Disorders and Coagulation, Careggi University Hospital, Firenze; ²Regional Reference Center for Inherited Bleeding and Thrombotic Disorders, Transfusion Medicine, Regina Margherita Children Hospital, Turin; ³Center for Hemorrhagic and Thrombotic Diseases, IRCCS A. Gemelli University Hospital Foundation, Roma; ⁴Department of Health Promotion, Maternal-Childhood, Internal Medicine of Excellence G. D’Alessandro, University of Palermo; ⁵Thrombosis and Hemostasis Unit, Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo; ⁶Angelo Bianchi Bonomi Hemophilia and Thrombosis Center and Fondazione Luigi Villa, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan; ⁷Pediatric Onco-Hematology Center, Microcitemico Hospital Cagliari; ⁸Pediatric Oncohematology and Bone Marrow Transplant “BMT” Unit, Children’s Hospital, Spedali Civili, Brescia; ⁹Hemophilia and Transfusion Center, Bufalini Hospital, Cesena; ¹⁰Hemophilia Center, Department of Transfusion Medicine, Hospital of Macerata; ¹¹Transfusion Medicine Department, SS. Annunziata Hospital, Chieti; ¹²B. Trambusti General and Specialised Pediatrics Unit, Giovanni XXIII Hospital, University of Bari; ¹³Hemophilia Center, Grande Ospedale Metropolitano, Reggio Calabria; ¹⁴Center for Hemorrhagic and Thrombotic Disorders, Pugliese Ciaccio Hospital, Catanzaro; ¹⁵Hemophilia and Thrombosis Center, Haematology Unit, Ospedale del Mare Hospital, Naples; ¹⁶Past President of the Italian Association of Hemophilia Centers, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.245

  593

  PDF: 20
• 

  Diagnostic challenges in current laboratory practice at Italian Hemophilia Centers: findings from a nationwide survey

  Tiziano Martini, Alessandra Valpreda, Marina Marchetti, Alberto Catalano, Laura Contino, Raimondo De Cristofaro, Augusto Bramante Federici, Ilaria Quaglia, Rossana Rossi, Rita Carlotta Santoro, Armando Tripodi, Angelo Claudio Molinari

  12-03-2026

  https://doi.org/10.4081/btvb.2026.431

  439

  PDF: 115

  Supplementary: 52
• 

  Management of anticoagulation in atrial fibrillation patients in Italy: insight from the Atrial Fibrillation-Survey on Anticoagulated Patients Register (AF-START)

  Daniela Poli, Walter Ageno, Emilia Antonucci, Salvatore Bradamante, Eugenio Bucherini, Paolo Chiarugi, Antonio Chistolini, Benilde Cosmi, Anna Falanga, Antonio Insana, Domenico Lione, Rosa Maria Lombardi, Giuseppe Malcangi, Rossella Marcucci, Giuliana Martini, Lucilla Masciocco, Carmelo Paparo, Daniele Pastori, Simona Pedrini, Vittorio Pengo, Pasquale Pignatelli, Andrea Toma, Sophie Testa, Gualtiero Palareti

  27-06-2023

  https://doi.org/10.4081/btvb.2023.84

  2171

  PDF: 651

  Supplementary File: 290