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  Anticoagulation in obese patients: challenges and strategies

  Alice Lipari, Esmeralda Capristo, Antonietta Ferretti, Erica De Candia

  18-09-2025

  https://doi.org/10.4081/btvb.2025.174

  2037

  PDF: 537

  HTML: 306

  XML: 191

• CO43 | Early platelet dysfunction in sepsis: an ICU pilot study S. Sorrentino¹, C. Gori², L. D’Innocenzo¹, M. De Siati¹, Mg. Bocci³, E. De Candia¹ | ¹Unit of Haemostasis and Thrombosis Diseases, Fondazione Policlinico Universitario A. Gemelli, IRCCS, Roma; ²UOC Shock & Trauma, Azienda Ospedaliera San Camillo Forlanini, Roma; ³National Institute for Infectious Diseases, Lazzaro Spallanzani, IRCCS, Roma, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.249

  658

  PDF: 17

• PO80 | Heparin-induced thrombocytopenia: a monocentric experience with danaparoid L. D’Innocenzo, S. Sorrentino, M. De Siati, A. Ferretti, E. De Candia | Unit of Haemostasis and Thrombosis Diseases, Fondazione Policlinico Universitario A. Gemelli, IRCCS, Roma, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.349

  702

  PDF: 13

• CO050 | INTERACTION BETWEEN DIRECT ORAL ANTICOAGULANTS AND ANTIEPILEPTIC DRUGS: A MULTICENTER OBSERVATIONAL STUDY A. Lipari¹, S. Sorrentino¹, M. De Siati¹, L. D'Innocenzo¹, A. Ferretti¹, D. Menichelli², V. Cammisotto², P. Pignatelli², G. Ragna³, MC. Vedovati³, C. Becattini³, G. Frisullo⁴, V. Forte⁵, T. Pirozzi¹, L. Di Gennaro¹, M. Basso¹, E. De Candia¹ | ¹Unit of Haemostasis and Thrombosis Diseases, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy; ²Department of Clinical Internal, Anesthesiological and Cardiovascular Sciences, Sapienza University of Roma, Roma, Italy; ³Department of Internal and Cardiovascular Medicine and Stroke Unit, University of Perugia, Perugia, Italy; ⁴Dipartimento di Neuroscienze, Organi di Senso e Torace, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy; ⁵Hematology, Department of Biomedicine and Prevention, University of Rome Tor Vergata, Roma, Italy

  Silvia Sorrentino

  26-10-2026

  https://doi.org/10.4081/btvb.2026.752

  31

  PDF: 13
• 

  Diagnosis and management of abnormal uterine bleeding in adolescence An expert Consensus Statement of SIGO (Italian Society of Gynecology and Obstetrics) and SISET (Italian Society for the Study of Hemostasis and Thrombosis)

  Roberto Mario Santi, Annamaria Fulghesu, Ezio Zanon, Erica De Candia, Elvira Grandone, Giancarlo Di Renzo, Claudia Succu, Valentina Tosto, Vincenzina Bruni, Paolo Gresele

  08-05-2024

  https://doi.org/10.4081/btvb.2024.106

  2859

  PDF: 739

• PO025 | CHARACTERIZATION OF PLATELET DYSFUNCTION IN NOONAN SYNDROME PATIENTS S. Sorrentino¹, I. Lazzareschi², A. Ferretti¹, R. Onesimo², A. Romano³, G. Zampino², C. Leoni², E. De Candia¹ | ¹UOS Piastrinopenie Congenite e Piastrinopatie, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Roma, Italy; ²UOC Pediatria, Fondazione Policlinico Universitario Agostino Gemelli IRCSS, Roma, Italy; ³UOC Oncologia Pediatrica, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Roma, Italy

  Silvia Sorrentino

  26-10-2026

  https://doi.org/10.4081/btvb.2026.841

  23

  PDF: 8

• PO084 | BRIDGING THE CLINICAL CHASM: GENETIC ANALYSIS AS A CONFIRMATORY TOOL IN MISMATCHED GLANZMANN THROMBASTHENIA R. Pastorino^1|3, F. Bocchi^1|3, A. Valpreda⁴, G. Murante^1|2|3, S. Bergonzi^1|2|3, M. Capetta^1|2|3, F. Valeri^1|2, C. Dainese^1|2, M. Gilestro⁵, D. Peruccio⁶, E. De Candia⁷, P. Concolino⁸, B. Bruno^2|3, A. Borchiellini^1|2 | ¹Regional Centre for Hemorrhagic and Thrombotic Diseases, AOU Città della Salute e della Scienza, Italy; ²Division of Hematology, AOU Città della Salute e della Scienza di Torino, Italy; ³Department of Molecular Biotechnology and Health Sciences, University of Turin, Italy; ⁴Central Laboratory Baldi and Riberi, AOU Città della Salute e della Scienza di Torino, Torino, Italy; ⁵AOU Citta' della Salute e della Scienza , PO Molinette, Anatomy and Pathological Histology 1 U, Department of Laboratory Medicine - Flow Cytometry Laboratory, Torino, Italy; ⁶AOU Citta' della Salute e della Scienza di Torino, Maternal-Infant and Trauma Transfusion Medicine, Regina Margherita Hospital, Department of Laboratory Medicine, Torino, Italy; ⁷Haemostasis and Thrombosis Unit, Fondazione Policlinico Universitario A.Gemelli, IRCCS, Department of Translational Medicine, Università Cattolica del Sacro Cuore, Roma, Italy; ⁸Fondazione Policlinico Universitario A. Gemelli, IRCCS, Department of Laboratory and Hematological Sciences, Unit of Clinical Chemistry, Biochemistry and Molecular Biology, UOSD of Molecular and Genomic Diagnostics, Roma, Italy

  Rebecca Pastorino

  26-10-2026

  https://doi.org/10.4081/btvb.2026.900

  20

  PDF: 7

• CO-45 | BRIDGING THE CLINICAL CHASM: GENETIC ANALYSIS AS A CONFIRMATORY TOOL IN MISMATCHED GLANZMANN THROMBASTHENIA R. Pastorino^1|3, F. Bocchi^1|3, A. Valpreda⁴, G. Murante^1|2|3, S. Bergonzi^1|2|3, M. Capetta^1|2|3, F. Valeri^1|2, C. Dainese^1|2, M. Gilestro⁵, D. Peruccio⁶, E. De Candia⁷, P. Concolino⁸, B. Bruno^2|3, A. Borchiellini^1|2 | ¹Regional Centre for Hemorrhagic and Thrombotic Diseases, AOU Città della Salute e della Scienza, Italy; ²Division of Hematology, AOU Città della Salute e della Scienza and University of Turin, Italy; ³Department of Molecular Biotechnology and Health Sciences, University of Turin, Italy; ⁴Central Laboratory Baldi and Riberi, AOU Città della Salute e della Scienza di Torino, Italy; ⁵AOU Citta' della Salute e della Scienza, PO Molinette, Anatomy and Pathological Histology 1 U, Department of Laboratory Medicine - Flow Cytometry Laboratory, Torino, Italy; ⁶AOU Citta' della Salute e della Scienza di Torino, Maternal-Infant and Trauma Transfusion Medicine, Regina Margherita Hospital, Department of Laboratory Medicine, Torino, Italy; ⁷Haemostasis and Thrombosis Unit, Fondazione Policlinico Universitario A.Gemelli, IRCCS, Department of Translational Medicine, Università Cattolica del Sacro Cuore, Roma, Italy; ⁸Fondazione Policlinico Universitario A. Gemelli, IRCCS, Department of Laboratory and Hematological Sciences, Unit of Clinical Chemistry, Biochemistry and Molecular Biology, UOSD of Molecular and Genomic Diagnostics, Roma, Italy

  Rebecca Pastorino

  14-10-2026

  https://doi.org/10.4081/btvb.2026.655

  48

  PDF: 12

• CO006 | PREVALENCE OF GASTROINTESTINAL BLEEDING IN GLANZMANN THROMBASTHENIA PATIENTS: RESULTS OF A WORLDWIDE SURVEY E. Falcinelli¹, L. Bury¹, S. Morais², M. de Oliveira², M. Kannan³, M. Faranoush⁴, D. Desprez⁵, V. Jean-Baptiste⁶, C. Santoro⁷, C. Falaise⁸, P. Saultier⁸, M. Fiore⁹, C. Albayrak¹⁰, A. Sánchez¹¹, J.M. Bastida¹², A. Artoni¹³, G. Castaman¹⁴, K. Gomez¹⁵, R. Schutgens¹⁶, L. Spiezia¹⁷, M. Sridharan¹⁸, N. Butta¹⁹, P. Buur van Kooten Niekerk²⁰, E. Leinøe²¹, B. Guillet²², C. Panagiotis²³, S. Crivelli²⁴, E. De Candia²⁵, M. Lewandowska²⁶, P. De Bonis²⁷, G. Kenet²⁸, F. Heubel-Moenen²⁹, J. Payne³⁰, L. Banov³¹, L. Puccetti³², M. Olivieri³³, M. Chitlur³⁴, M. Lambert³⁵, A. Pecci³⁶, D. Martínez-Carballeira³⁷, E. Zetterberg³⁸, J. Curnow³⁹, M. Napolitano⁴⁰, A. Morotti⁴¹, R.C. Santoro⁴², R. Johann⁴³, S. Saulyte Trakymiene⁴⁴, A. Falanga⁴⁵, C. Casas⁴⁶, E. Zanon⁴⁷, J. Moppet⁴⁸, N.M. Popa-Fotea⁴⁹, P. Gresele¹ | ¹Department of Medicine and Surgery, Section of Internal and Cardiovascular Medicine, University of Perugia, Italy; ²Centro Hospitalar Universitário de Santo António, Portugal; ³Blood and Vascular Biology Research Lab, Department of Biotechnology, Central University of Tamil Nadu, India; ⁴Iranian Hemophilia and Thrombophilia Association, MAHTA, Iran; ⁵CRC MHC Hopital Universaitire de Strasbourg, France; ⁶CHRU de Tours, University Hospital of Tours, France; ⁷UOC Ematologia, Azienda Ospedaliero Universitaria Policlinico Umberto I, Roma, Italy; ⁸AP-HM Timone, Marseille, France; ⁹CHU Bordeaux, France; ¹⁰Mayıs University Medical Faculty Pediatric Hematology and Oncology Dept, Türkiye; ¹¹Hospital Universitario Morales Meseguer – Centro Regional de Hemodonación, Murcia, Spain; ¹²Complejo Asistencial Universitario De Salamanca, Spain; ¹³Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milano, Italy; ¹⁴Azienda Ospedaliera Universitaria Careggi Florence, Italy; ¹⁵Royal Free Hospital, London, UK; ¹⁶Center for Benign Haematology, Thrombosis and Haemostasis, Van Creveldkliniek, UMC Utrecht, The Netherlands; ¹⁷University of Padova, Italy; ¹⁸Mayo Clinic, Rochester, USA; ¹⁹Hospital Universitario La Paz-IdiPAZ, Madrid, Spain; ²⁰Aarhus University Hospital, Denmark; ²¹Department of Hematology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark; ²²University Hospital of Rennes, France; ²³Blood unit and National Reference Center for Congenital Bleeding Disorders, ''Laiko'' General Hospital, Greece; ²⁴Ospedale L. Sacco e Polo Universitario, Milano, Italy; ²⁵Università Cattolica del Sacro Cuore-Roma, Fondazione Policlinico Universitario A. Gemelli IRCCS, Italy; ²⁶Indiana Hemophilia and Thrombosis Center Innovative Hematology, USA; ²⁷IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy; ²⁸Sheba Medical Center, Israel; ²⁹Department of Hematology Internal Medicine, Maastricht University Medical Center and Hemophilia Treatment Center Nijmegen Eindhoven Maastricht and CARIM, Maastricht University, Maastricht, Netherlands; ³⁰Sheffield Children’s NHS foundation Trust, UK; ³¹Hemostasis and Thrombosis Unit, Gaslini Children’s Hospital, Italy; ³²University Teaching Hospital of Siena, Italy; ³³Pediatric Thrombosis and Hemostasis Unit, Dr. von Hauner Childreńs Hospital, LMU Munich, Munich, Germany; ³⁴Children's Hospital of Michigan, USA; ³⁵Children’s Hospital of Philadelphia, USA; ³⁶IRCCS Policlinico San Matteo Foundation and University of Pavia, Italy; ³⁷Instituto de Investigación Sanitaria del Principado de Asturias (ISPA), Spain; ³⁸Department of Hematology, Coagulation Unit, Skane University hospital, Sweden; ³⁹Westmead Hospital, Sydney, Australia; ⁴⁰PROMISE Department, University of Palermo, Italy; ⁴¹AOU San Luigi Gonzaga Hospital, University of Turin, Italy; ⁴²Hemostasis and Thrombosis, Az. Osp. Univ. Dulbecco, Catanzaro, Italy; ⁴³Hospital Center of Le Mans, France; ⁴⁴Vilnius University Hospital Santaros Klinikos, Lithuania; ⁴⁵ASST Papa Giovanni XXIII, Bergamo, Italy; ⁴⁶Hospital San José, Bogotà, Colombia; ⁴⁷Haemophilia Center-General Medicine, Padova University Hospital, Padova, Italy; ⁴⁸University Hospitals Bristol NHS Foundation Trust, UK; ⁴⁹University of Medicine and Pharmacy “Carol Davila”, Bucharest, Romania

  Loredana Bury

  26-10-2026

  https://doi.org/10.4081/btvb.2026.708

  39

  PDF: 11

• PO086 | INHERITED PLATELET GPIV DEFICIENCY: FIRST DESCRIPTION OF TWO PATIENTS WITH BLEEDING DIATHESIS L. Bury¹, S. Sorrentino², E. Falcinelli¹, G. Guglielmini¹, V. Fazzi¹, A. Ferretti², P. Concolino^3|4, F. Cirillo⁵, P. Gresele¹, E. De Candia^2|6 | ¹Department of Medicine and Surgery, Section of Internal and Cardiovascular Medicine, University of Perugia, Perugia, Italy; ²Dipartimento di Medicina e Chirurgia Traslazionale, Università Cattolica del Sacro Cuore, Facoltà di Medicina, Roma, Italy; ³Departmental Unit of Molecular and Genomic Diagnostics, Fondazione Policlinico Gemelli IRCCS, Roma, Italy; ⁴Genomics Core Facility, G-STeP, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Roma, Italy; ⁵Department of Clinical Medicine and Surgery, Federico II University of Naples, Naples, Italy; ⁶Dipartimento di Scienze di Laboratorio ed Ematologiche, Policlinico Universitario A. Gemelli IRCCS, Roma, Italy. L. Bury first authorship, P. Gresele senior authorship

  Loredana Bury

  26-10-2026

  https://doi.org/10.4081/btvb.2026.902

  24

  PDF: 9
• 

  Persistence of functional anti-PF4 antibodies and neutrophil activation in vaccine-induced immune thrombotic thrombocytopenia

  Eleonora Petito, Anna Maria Mezzasoma, Emanuela Falcinelli, Chiara Conti, Erica De Candia, Raimondo De Cristofaro, Silvia Sorrentino, Gian Marco Podda, Mariangela Scavone, Anna Falanga, Marina Marchetti, Luca Barcella, Stefania Basili, Lucia Stefanini, Andrea Boccatonda, Laura Contino, Patrizia Sciancalepore, Igor Florio, Egidio Imbalzano, Rossella Marcucci, Angela Rogolino, Patrizia Noris, Marta Panella, Rita Santoro, Maria Costanza Turi, Gaetano Vaudo, Rosa Curcio, Paolo Gresele

  18-11-2025

  https://doi.org/10.4081/btvb.2025.400

  967

  PDF: 178

  HTML: 206

• CO105 | THALIDOMIDE FOR RECURRENT GASTROINTESTINAL BLEEDING IN RARE BLEEDING DISORDERS AND VENOUS MALFORMATIONS: A MONOCENTRIC EXPERIENCE M. De Siati^1|2, F.G. Perretta^1|2, F. Ricci^1|2, A. Ferretti¹, M. Comand^1|2, S. Sorrentino¹, L. D’Innocenzo^1|2, D. Feliciani², B. Funaro², M.E. Riccioni³, A. Gasbarrini^2|4, E. De Candia^1|2 | ¹UOSD Malattie Emorragiche e Trombotiche, Fondazione Policlinico Agostino Gemelli IRCCS, Roma 00168, Italy; ²Department of Translational Medicine and Surgery, Catholic University of the Sacred Heart, Roma, Italy; ³Digestive Endoscopy Unit, Fondazione Policlinico Universitario Agostino Gemelli, IRCCS, Università Cattolica del Sacro Cuore, Largo Agostino Gemelli, Roma 00168, Italy; ⁴Department of Medical and Surgical Sciences, Digestive Disease Center, Universitary Policlinic Agostino Gemelli Foundation IRCCS, Roma, Italy

  Silvia Sorrentino

  26-10-2026

  https://doi.org/10.4081/btvb.2026.807

  25

  PDF: 8

• PO151 | HIGH-RISK SURGERY IN SEVERE HAEMOPHILIA B: PERIOPERATIVE MANAGEMENT WITH ALBUTREPENONACOG ALFA F. Ricci, M. De Siati, M. Comand, F.G. Perretta, A. Ferretti, M. Basso, E. De Candia, R. De Cristofaro | Fondazione Policlinico Universitario Gemelli IRCCS, Roma, Italy

  Silvia Sorrentino

  26-10-2026

  https://doi.org/10.4081/btvb.2026.967

  24

  PDF: 9

• PO120 | UNEXPLAINED BLEEDING IN A YOUNG WOMAN: A CASE REPORT OF SUPERWARFARIN TOXICITY M. Guarascio¹, A. Ferretti², L. Di Gennaro², M. Comand², E. De Candia² | ¹Internal Medicine Unit, Vito Fazzi Hospital, Lecce, Italy; ²Department of Translational Medicine and Surgery, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Roma, Italy

  Matteo Guarascio

  26-10-2026

  https://doi.org/10.4081/btvb.2026.936

  29

  PDF: 11