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Bleeding, Thrombosis and Vascular Biology

Editor-in-Chief: Giovanni de Gaetano, Italy | eISSN: 2785-5309

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  • CO040 | MAJOR BLEEDING IN PATIENTS WITH ACUTE PULMONARY EMBOLISM: RESULTS FROM THE COPE STUDY C. Becattini1, L.A. Cimini1, M. Vatrano2, F. Lucà3, E. De Curtis4, S.A. Harari5, G.V. Lettica6, S. D’Orazio7, A. Fabbri8, F. Pomero9, A.P. Maggioni10, G. Agnelli1, M. Gulizia10 | 1Internal, Vascular and Emergency Medicine– Stroke Unit, University of Perugia, Perugia, Italy; 2Cardiology Unit, A.O.U. "Renato Dulbecco", P.O. "Pugliese", Catanzaro, Italy; 3Division of Cardiology – Grande Osp. Metropol.-Bianchi Melacrino, Reggio Calabria, Italy; 4Pronto Soccorso e Medicina d’Urgenza, Ospedale Santo Stefano, Prato, Italy; 5Pneumologia, Multimedica Ospedale San Giuseppe, Milano, Italy; 6Cardiologia-UTIC, Ospedale Riccardo Guzzardi, Vittoria-Ragusa, Italy; 7Cardiologia, Ospedale della Valdichiana Aretina Santa Margherita, Cortona, Italy; 8Pronto Soccorso, Medicina d’Urgenza, 118, Azienda USL della Romagna – Forlì, Italy; 9Internal Medicine, Michele and Pietro Ferrero Hospital, Verduno (CN), Italy; 10ANMCO Research Center, Heart Care Foundation, Firenze, Italy

    Ludovica Anna Cimini
    26-10-2026
    https://doi.org/10.4081/btvb.2026.742
    0
    PDF: 0
  • CO052 | INCREMENTAL PROGNOSTIC VALUE OF ECHOCARDIOGRAPHIC MARKERS OF RIGHT VENTRICULAR FUNCTION IN ACUTE PULMONARY EMBOLISM: AN INDIVIDUAL PATIENT DATA ANALYSIS L.A. Cimini1, E. Yuriditsky2, D. Jiménez3|4|5, M. Zuin6, M. Monreal7, G. Agnelli1, C. Becattini1 | 1Internal and Cardiovascular Medicine-Stroke Unit, University of Perugia, Italy; 2Division of Cardiology, Department of Medicine NYU Langone Health New York NY, USA; 3Respiratory Department, Ramón y Cajal Hospital (IRYCIS), Madrid, Spain; 4Department of Medicine, Universidad de Alcalá (IRYCIS), Madrid, Spain; 5CIBER de Enfermedades Respiratorias (CIBERES), Madrid, Spain; 6Dipartimento di Medicina Traslazionale, Università degli Studi, Ferrara, Italy; 7Cátedra de Enfermedad Tromboembólica, Universidad Católica San Antonio de Murcia, Spain

    Ludovica Anna Cimini
    26-10-2026
    https://doi.org/10.4081/btvb.2026.754
    0
    PDF: 0
  • CO042 | BLEEDING RISK IN PATIENTS RECEIVING CONCURRENT TREATMENT WITH DIRECT ORAL ANTICOAGULANTS AND CORTICOSTEROIDS: A SYSTEMATIC REVIEW M.A. Capparella1, R. Talerico2, C. Cavallaro2, M. Iorio2, F. Bossi1, A. Porfidia2, K. Abe3, M. Biglietto4, A. Chistolini4, A. Holt5, L. Lahousse6|7, R. Pola2, C. Becattini1, M.C. Vedovati1 | 1Internal, Vascular and Emergency Medicine – Stroke Unit, University of Perugia, Italy; 2Thrombosis Unit, Department of Geriatric, Orthopedic, and Rheumatologic Sciences, Fondazione Policlinico A. Gemelli IRCCS, Roma, Italy; 3Division of Gastroenterology, Department of Medicine, Teikyo University School of Medicine, Tokyo, Japan; 4Hematology, Department of Translational and Precision Medicine, Sapienza University of Roma, Italy; 5Department of Cardiology, Copenhagen University Hospital – Herlev and Gentofte, Copenhagen, Denmark; 6Department of Bioanalysis, Pharmaceutical Care Unit, Faculty of Pharmaceutical Sciences, Ghent University, Ghent, Belgium; 7Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands

    Maria Alessandra Capparella
    26-10-2026
    https://doi.org/10.4081/btvb.2026.744
    0
    PDF: 0
  • CO053 | PROGNOSTIC IMPACT OF RIGHT VENTRICULAR DYSFUNCTION AND HYPOXEMIA IN HEMODYNAMICALLY STABLE ACUTE PULMONARY EMBOLISM: AN INDIVIDUAL PATIENT DATA META-ANALYSIS L.A. Cimini1, D. Jiménez2|3|4, A. Weekes5, S. Vanni6, S. Rajagopal7, F. Pieralli8, G. Agnelli1, C. Becattini1 | 1Internal and Cardiovascular Medicine-Stroke Unit, University of Perugia, Italy; 2Respiratory Department, Ramón y Cajal Hospital (IRYCIS), Madrid, Spain; 3Department of Medicine, Universidad de Alcalá (IRYCIS), Madrid, Spain; 4CIBER de Enfermedades Respiratorias (CIBERES), Madrid, Spain; 5Department of Emergency Medicine Atrium Health's Carolinas Medical Center, Charlotte, North Carolina, USA; 6Dipartimento Medicina Sperimentale e Clinica, Università degli Studi di Firenze, Azienda Ospedaliero-Universitaria Careggi, Firenze, Italy; 7Division of Cardiovascular Medicine, Department of Medicine, Duke University School of Medicine and Medical Center, Durham, NC, UK; 8Internal Medicine and Intermediate Care Unit, Careggi University Hospital, Firenze, Italy

    Ludovica Anna Cimini
    26-10-2026
    https://doi.org/10.4081/btvb.2026.755
    0
    PDF: 0
  • CO012 | LONG-TERM RISK OF RECURRENT VENOUS THROMBOEMBOLISM IN ADULT PATIENTS WITH ACTIVE CANCER AND FIRST CATHETER-RELATED UPPER EXTREMITY DEEP VEIN THROMBOSIS AFTER DISCONTINUATION OF ANTICOAGULANT TREATMENTS AND LINE REMOVAL: A RETROSPECTIVE MULTI-CENTER COHORT STUDY – CANCER-CRT STUDY L. Girardi1|2, W. Ageno3, L. Bertù1, C. Lodigiani4, L.A. Ciuffini4, M.C. Vedovati5, C. Becattini5, A. Sammarco6, G. Camporese6, G. Cuni1|7, C. Ambaglio7, M.P. Donadini1 | 1Research Center on Thromboembolic Diseases and Antithrombotic Treatment, Department of Medicine and Surgery, University of Insubria, Varese, Italy; 2Department of Medicine, The Ottawa Hospital Research Institute, University of Ottawa, Ontario, Canada; 3Department of Medicine, University of Padua, Padova, Italy; 4Center for Thrombosis and Hemorrhagic Diseases, IRCCS Humanitas Research Hospital, Rozzano, Milano, Italy; 5Internal and Cardiovascular Medicine-Stroke Unit, University of Perugia, Perugia, Italy; 6Clinica Medica 1, Department of Medicine, DIMED, Padova University Hospital, Padova, Italy; 7Immunohematology and Transfusion Medicine, Department of Transfusion Medicine and Hematology, ASST Papa Giovanni XXIII, Bergamo, Italy

    Laura Girardi
    26-10-2026
    https://doi.org/10.4081/btvb.2026.714
    0
    PDF: 0
  • PO105 | IMPACT OF ECOG PERFORMANCE STATUS ON CANCER-ASSOCIATED THROMBOSIS TREATED WITH DOACS: DATA FROM A MULTICENTER COHORT STUDY R. Talerico1, F. Mancinetti1, C. Sacco2, M. Mazzetti3, E. Campello4, S. Birocchi5, S. Beccatini6, A. Porfidia1, C. Lodigiani2, P. Simioni4, G.M. Podda5, I. Mastandrea2, C. Becattini6, R. Pola1, M.C. Vedovati6 | 1Thrombosis Unit, Department of Geriatric, Orthopedic, and Rheumatologic Sciences, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy; 2Thrombosis and Hemorrhagic Diseases Unit, IRCCS Humanitas Research Hospital, Rozzano, Milano, Italy; 3Interdisciplinary Internal Medicine, Careggi University Hospital, Firenze, Italy; 4First Chair of Internal Medicine and Thrombotic and Hemorrhagic Diseases Unit, Department of Medicine, University of Padova, Italy; 5Medicine II Unit, ASST Santi Paolo e Carlo, Department of Health Sciences, University of Milano, Milano, Italy; 6Internal, Vascular and Emergency Medicine– Stroke Unit, University of Perugia, Perugia, Italy

    Rosa Talerico
    26-10-2026
    https://doi.org/10.4081/btvb.2026.921
    0
    PDF: 0
  • CO093 | PROGNOSTIC ROLE OF ANTIPLATELET ANTIBODY TESTING IN IMMUNE THROMBOCYTOPENIA G. Maraziti, C. Schiavone, A. Fiaccadori, A. Mezzasoma, C. Becattini | Internal and Emergency Medicine - Stroke Unit, S. Maria della Misericordia Hospital – University of Perugia, Perugia, Italy

    Giorgio Maraziti
    26-10-2026
    https://doi.org/10.4081/btvb.2026.795
    0
    PDF: 0
  • PO027 | IGFBP-6 REGULATES PLATELET PROCOAGULANT ACTIVITY AT THE INTERFACE BETWEEN INFLAMMATION AND COAGULATION L. Bury1, E. Falcinelli1, E. Petito1, L. Leijonancker2, H. van Ooijen2, S. Petkov2, A.R.D. Coda3, C. Raucci1, V. Fazzi1, D. Sarnà1, C. Becattini1, P. Gresele1, A. Liso4 | 1Department of Medicine and Surgery, Section of Internal and Cardiovascular Medicine, University of Perugia, Perugia, Italy; 2Pixelgen Technologies AB, Stockholm, Sweden; 3C.R.E.A.T.E.-Center for Research and Innovation in Medicine, Department of Medical and Surgical Sciences, University of Foggia, Italy; 4Department of Medicine and Surgery, University of Perugia, Perugia and Hematology/Oncology Unit, Terni Hospital, Terni, Italy

    Loredana Bury
    26-10-2026
    https://doi.org/10.4081/btvb.2026.843
    0
    PDF: 0
  • CO001 | DERIVATION AND VALIDATION OF THE BLEEPE SCORE FOR RISK STRATIFICATION OF MAJOR BLEEDING IN PATIENTS WITH ACUTE PULMONARY EMBOLISM M. Vedovati1, L. Cimini1, V. Valeriano2, I. Montenovo1, A. Murgia3, L. Pierpaoli4, G. Tratar5, S. Zaccaroni6, A. Bongarzoni7, A. Vinci1, A. Mavri5, L. Martinelli8, G. Pepe9, S. Cozzio10, C. Becattini1 | 1University of Perugia, Perugia, Italy; 2Sandro Pertini Hospital, Roma, Italy; 3SS. Annunziata Hospital, Sassari, Italy; 4S. Maria delle Croci Hospital, Ravenna, Italy; 5University Medical Centre Ljubljana, Ljubljana, Slovenia; 6Maggiore Hospital, Bologna, Italy; 7ASST Santi Paolo e Carlo-PO San Carlo, Milano, Italy; 8Città di Castello Hospital, Città di Castello, Italy; 9Versilia Hospital, Tuscany North West Health System, Lido di Camaiore (LU), Italy; 10Rovereto Hospital, Rovereto, Italy

    Maria Cristina Vedovati
    26-10-2026
    https://doi.org/10.4081/btvb.2026.703
    2
    PDF: 0
  • CO046 | BLEEDING RISK FACTOR–BASED PHENOTYPES AND THEIR ASSOCIATION WITH MORTALITY AND HEMORRHAGIC OUTCOMES IN ATRIAL FIBRILLATION T. Bucci1, A.G. Rigutini1, A. Perrotta1, A. Moffa1, C. Seviroli1, M. Giustozzi2, M.C. Vedovati1, C. Becattini1 | 1Internal, Vascular and Emergency Medicine - Stroke Unit, University of Perugia, Perugia, Italy; 2SSD Angiology, San Giovanni Battista Hospital, Foligno, Italy

    Tommaso Bucci
    26-10-2026
    https://doi.org/10.4081/btvb.2026.748
    0
    PDF: 0
  • CO037 | PERFORMANCE OF A QUALITATIVE POINT-OF-CARE TEST IN PATIENTS EXPERIENCING ACUTE THROMBOEMBOLIC OR MAJOR BLEEDING EVENTS TREATED WITH DOACs: THE T-BLEEDOAC MULTICENTER PROSPECTIVE COHORT STUDY M. Vedovati1, G. Pepe2, S. Vanni3, E. Campello4, F. Morello5, S. Beccatini1, D. Giudici1, F. Lucarini2, L. Parmeggiani3, G. Fabiani3, P. Simioni4, M. Santoro5, P. Nazerian6, M. Mosconi1, C. Becattini1 | 1University of Perugia, Perugia, Italy; 2Versilia Hospital, Tuscany North West Health System, Lido di Camaiore (LU), Italy; 3Università di Firenze, Firenze, Italy; 4University of Padua, Padova, Italy; 5A.O.U. Città della Salute e della Scienza, Torino, Italy; 6Careggi University Hospital, Firenze, Italy

    Maria Cristina Vedovati
    26-10-2026
    https://doi.org/10.4081/btvb.2026.739
    0
    PDF: 0
  • CO050 | INTERACTION BETWEEN DIRECT ORAL ANTICOAGULANTS AND ANTIEPILEPTIC DRUGS: A MULTICENTER OBSERVATIONAL STUDY A. Lipari1, S. Sorrentino1, M. De Siati1, L. D'Innocenzo1, A. Ferretti1, D. Menichelli2, V. Cammisotto2, P. Pignatelli2, G. Ragna3, MC. Vedovati3, C. Becattini3, G. Frisullo4, V. Forte5, T. Pirozzi1, L. Di Gennaro1, M. Basso1, E. De Candia1 | 1Unit of Haemostasis and Thrombosis Diseases, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy; 2Department of Clinical Internal, Anesthesiological and Cardiovascular Sciences, Sapienza University of Roma, Roma, Italy; 3Department of Internal and Cardiovascular Medicine and Stroke Unit, University of Perugia, Perugia, Italy; 4Dipartimento di Neuroscienze, Organi di Senso e Torace, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy; 5Hematology, Department of Biomedicine and Prevention, University of Rome Tor Vergata, Roma, Italy

    Silvia Sorrentino
    26-10-2026
    https://doi.org/10.4081/btvb.2026.752
    0
    PDF: 1
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Vol. 5 No. 4 (2026)
Platelets versus monocytes as cellular sources of blood-borne tissue factor: a quantitative and functional comparison in healthy subjects...
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Bleeding, Thrombosis and Vascular Biology

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