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• PO31 | Comparative analysis of anticoagulant therapy in patients over 90 years old: vitamin K antagonists versus direct oral anticoagulants G. Sottilotta¹, P. Arrigo², S. Cuzzocrea¹, D. Megalizzi¹, F. Luise³ | ¹UOSD Microcitemie, Emostasi e Trombosi, Grande Ospedale Metropolitano di Reggio Calabria; ²Associazione Italiana Pazienti Anticoagulati, Sezione di Reggio Calabria; ³Laboratorio Analisi. Grande Ospedale Metropolitano di Reggio Calabria, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.292

  305

  PDF: 0

• PO43 | Extended treatment with reduced dose of direct oral anticoagulants in patients with venous thromboembolism: a retrospective study A. Pannunzio¹, E. Valeriani¹, I.M. Palumbo¹, D. Menichelli¹, T. Brogi², S. Marucci², D. Pastori², P. Pignatelli² | ¹Department of General Surgery and Surgical Specialty, Sapienza University of Roma; ²Department of Clinical Internal, Anesthesiological and Cardiovascular Sciences, Sapienza University of Roma, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.306

  311

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• CO33 | Acquired hemophilia A in Liguria, Italy: what six years of data reveal C. Vernarecci¹, A. C. Molinari¹, P. Ballarino², M. Caiti², E. Cenni², P. Moscatelli², L. Banov¹ | ¹IRCCS Istituto Giannina Gaslini, Genova; ²IRCCS Policlinico San Martino, Genova, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.240

  290

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• CO09 | Long term effectiveness and safety of direct oral anticoagulants in patients with factor V Leiden and/or prothrombin gene mutation and venous thromboembolism: a single centre, retrospective cohort study I.M. Palumbo¹, E. Valeriani^1,2, A. Pannunzio¹, S. Marucci³, D. Menichelli¹, D. Pastori^3,4, P. Pignatelli³ | ¹Department of General Surgery and Surgical Specialty, Sapienza University of Roma; ²Department of Infectious Disease, Azienda Ospedaliero-Universitaria Policlinico Umberto I, Roma; ³Department of Clinical Internal, Anaesthesiologic and Cardiovascular Sciences, Sapienza University of Roma; ⁴IRCCS Neuromed, Pozzilli, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.213

  347

  PDF: 0

• PO08 | Efficacy and safety of thromboprophylaxis in hospitalized hematological patients: a monocenter retrospective study S. Cordella^1,2, V. Coluccio³, M. Luppi¹, M. Marietta¹ |  ¹Department of Medical and Surgical Sciences, Section of Hematology. University of Modena and Reggio Emilia, Azienda Ospedaliero-Universitaria di Modena; ²Clinical and Experimental Medicine PhD Programme, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena; ³Department of Hematology, Unità Sanitaria Locale di Modena, Italy 

  22-10-2025

  https://doi.org/10.4081/btvb.2025.270

  288

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• CO16 | The predictive value of high-sensitivity C-reactive protein for assessing thrombosis risk in non-small cell lung cancer P. Gomez-Rosas^1,2, M. Marchetti^1,3, L. Russo¹, C.J. Tartari¹, S. Bolognini¹, C. Ticozzi¹, F. Schieppati¹, A. D’Alessio⁴, R. Labianca⁵, A. Falanga^1,3 All on behalf of the Hypercan Investigators | ¹Hospital Papa Giovanni XXIII, Bergamo, Italy; ²Cardiovascular Research Institute Maastricht, CARIM, Maastricht University, Maastricht, the Netherlands; ³School of Medicine and Surgery, University of Milan Bicocca, Italy; ⁴University Vita-Salute San Raffaele, Milan, Italy; ⁵Fondazione ARTET Onlus, Bergamo, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.220

  311

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• PO95 | Idiopathic thrombocytopenic purpura in tuberculosis M. Shani | Università di Medicina Tirana, Albania

  22-10-2025

  https://doi.org/10.4081/btvb.2025.365

  371

  PDF: 0

• CO01 | Statin therapy for the prevention of venous thromboembolism in cancer patients: a systematic review and meta-analysis F. Catalani, R. Del Giorno, R. Canevascini, W. Ageno, L. Gabutti, G. Prouse, L. Giovannacci | Ospedale Regionale di Bellinzona, Switzerland.

  22-10-2025

  https://doi.org/10.4081/btvb.2025.199

  364

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• PO16 | Antithrombotic treatment and outcomes in retinal vein occlusion: a retrospective cohort study and comparison with historical group S.A. Malerba^1,2, M.T. Sartori¹, G. Libralon¹, C. Dalla Porta¹, P. Simioni¹ | ¹First Medical Clinic, Department of medicine- DIMED, Università degli Studi di Padova; ²Medicina Generale, Ospedale dell’Angelo, Mestre, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.277

  305

  PDF: 0

• PO35 | Cerebral veins thrombosis in patients with and without myeloproliferative neoplasm: a real life retrospective monocentric study I. Bertozzi, M.T. Sartori, M. Zerbinati, G. Libralon, A. Galbiati, P. Simioni | First Medical Clinic, Department of Medicine - DIMED, Università degli Studi di Padova, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.298

  294

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• PO56 | Safety of anticoagulant treatment in patients with splanchnic vein thrombosis and history of portal hypertension-related bleeding R. Talerico¹, S. Pellegrino¹, A. Plessier², F.R. Ponziani³, A. Porfidia¹, F. Landi¹, A. Gasbarrini³, R. Pola¹, F. Santopaolo³ | ¹Department of Geriatric, Orthopedic, and Rheumatologic Sciences, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Roma, Italy; ²Université de Paris, AP-HP, C, DMU DIGEST, Centre de Référence des Maladies Vasculaires du Foie, FILFOIE, ERN RARE-LIVE. Centre de recherche sur l’inflammation, Inserm, Paris, France; ³Department of Medical and Surgical Sciences, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Roma, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.325

  292

  PDF: 0

• CO02 | Hepatic fibrosis as predictor of cancer-associated thrombosis in patients with intrahepatic cholangiocarcinoma Y. Frion-Herrera^1,2, C. Venturin^1,3, M. Cadamuro⁴, J. Gasparello⁵, C.M. Radu¹, M. Fassan⁵, C. Mescoli⁶, U. Cillo⁷, E. Gringeri⁷, G. Zanus⁸, L. Fabris^1,3, P. Simioni¹ | ¹Clinical Medicine and Thrombotic and Haemorrhagic Disease Unit, and Haemophilia Center, Padua University-Hospital, Department of Medicine [DIMED], University of Padua, Italy; ²Department of Biology [DiBio], University of Padua, Italy; ³Department of Internal Medicine, Digestive Disease Section, Liver Center, Yale University, New Haven, CT, USA; ⁴School of Medicine and Surgery, University of Milan-Bicocca, Milan, Italy; ⁵Department of Pathology Ca’ Foncello Hospital, ULSS2 Marca Trevigiana, Italy; ⁶Pathology Unit, Padua University-Hospital, Padua, Italy; ⁷Hepatobiliary Surgery and Liver Transplantation Unit, Padua University-Hospital, Department of Surgery, Oncology and Gastroenterology [DISCOG], University of Padua, Italy; ⁸General Surgery Unit, Ca’ Foncello Hospital, ULSS2 Marca Trevigiana, Department of Surgery, Oncology and Gastroenterology [DISCOG], University of Padua, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.207

  385

  PDF: 0

• PO13 | Monitoring of anti-factor XA activity levels in patients treated with direct oral anticoagulants and concomitant tyrosine kinase inhibitors agents: a monocentric experience E. Santacroce^1,2, C. Santoro¹, E. Baldacci¹, S. Ligia¹, R. Mormile¹, M. Biglietto¹, M. Totaro¹, F. R. Mauro¹, M. Breccia¹, A. Chistolini¹ | ¹Department of Translational and Precision Medicine, Haematology, Sapienza University of Roma; ²Department of Clinical and Molecular Medicine, Sapienza University of Roma, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.313

  311

  PDF: 0

• CO27 | Intracerebral hemorrhage in hemophilia A and B: a 10-year prospective multicenter study in Italy (2012–2022) E. Zanon¹, A. Napolitano¹, A. Porreca², F. Demartis³, A. Coppola⁴, C. Santoro⁵, I. Cantori⁶, A. C. Molinari⁷, C. Biasioli⁸, M. Luciani⁹, G. Sottilotta¹⁰, B. Pollio¹¹, A. Borchiellini¹², A. Tosetto¹³, P. Flora¹⁴, P. Simioni¹ | ¹Haemophilia Center, First Chair of Internal Medicine, Department of Medicine, University-Hospital of Padua Medical School, Padua; ²Department of Human Sciences and Promotion of the Quality of Life, Unit of Clinical and Molecular Epidemiology IRCCS San Raffaele Roma Open University, Roma; Unit of Clinical and Molecular Epidemiology IRCCS San Raffaele, Roma; ³Centre for Bleeding Disorders, Careggi University Hospital of Firenze; ⁴Azienda Ospedaliero Universitaria di Parma; ⁵Hematology Division, Umberto I University Hospital of Roma; ⁶Haemophilia Center, Department of Transfusion Medicine, Hospital of Macerata; ⁷IRCCS Istituto Giannina Gaslini, Genova; ⁸Haemophilia and Transfusion Centre, Bufalini Hospital, Cesena; ⁹Children’s Hospital Bambino Gesù, Roma; ¹⁰Haemophilia Center, Department of Onco-Hematology and Radioterapy, Hospital of Reggio Calabria; ¹¹Haemophilia Pediatric Center, Transfusion Medicine, City of Health and Science of Turin; ¹²City of Health and Science of Turin; ¹³Hemorrhagic and Thrombotic Diseases Unit, S. Bortolo Hospital of Vicenza; ¹⁴RCCS Foundation Ca’ Granda Maggiore Policlinico Hospital, Milan, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.233

  331

  PDF: 0

• PO29 | Quality of anticoagulation as a predictor of early left ventricular thrombosis resolution: a retrospective cohort study A. Pannunzio¹, I.M. Palumbo¹, M.P. Donadini², D. Santagata², W. Ageno², F. Dragoni³, A. Chistolini³, C. Becattini⁴, K. Satula⁴, D. Menichelli¹, D. Pastori¹, P. Pignatelli⁵, E. Valeriani¹ | ¹Department of General Surgery and Surgical Specialty Paride Stefanini, Sapienza University of Roma; ²Department of Medicine and Surgery, University of Insubria, Varese; ³Hematology, Department of Translational and Precision Medicine, Sapienza University of Roma; ⁴Internal Vascular and Emergency Medicine - Stroke Unit, University of Perugia; ⁵Department of Clinical Internal, Anesthesiological and Cardiovascular Sciences, Sapienza University of Roma, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.290

  295

  PDF: 0

• CS04 | Association between elevated plasma levels of tissue plasminogen activator and occult cancer risk: a nested case-cohort analysis in 10,294 healthy subjects S. Bolognini^1,2, C. Ticozzi¹, P. Gomez-Rosas^1,3, L. Russo^1,2, Cj. Tartari^1,2, F. Schieppati^1,2, G. Sampietro⁴, L. Barcella¹, M. Marchetti^1,2, A. Falanga^1,2 | ¹Immunohematology and Transfusion Medicine, Hospital Papa Giovanni XXIII, Bergamo, Italy; ²School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy; ³Maastricht University Medical Center, Cardiovascular Research Institute Maastricht, The Netherlands; ⁴Unit of Epidemiology and Statistics, ATS Bergamo, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.201

  354

  PDF: 0

• CO05 | Long-term management of upper extremity catheter-related thrombosis in female patients with cancer: a retrospective cohort study Chiara Cavallaro^1,2, Paolo Santini^1,2, Laura Leoni³, Carolina Mosoni^1,2, Silvia D’Ambrosio^1,2, Francesco Mancinetti^1,2, Nicola Coletta^1,2, Michela Iorio^1,2, Angelo Porfidia^1,2, Alessandro D’Errico^1,2, Rosa Talerico^1,2, Roberto Pola^1,2 | ¹Department of Aging, Orthopedic, and Rheumatologic Sciences, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome; ²Università Cattolica del Sacro Cuore, Rome; ³Vita-Salute University, San Raffaele Hospital IRCCS, Milan, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.309

  349

  PDF: 0

• CO20 | Coagulation alterations as prognostic indicators in septic patients L. Baratti¹, S. N. Pasturenzi¹, P. Onorato², W. Ageno³, F. Cortellaro², M.P. Donadini^2,4 | ¹Scuola di Medicina, Università degli Studi dell’Insubria, Varese; ²Pronto Soccorso e Medicina d’Urgenza, Ospedale di Circolo, Varese; ³Dipartimento di Medicina, Università degli Studi di Padova; ⁴Dipartimento di Medicina e Chirurgia, Università degli Studi dell’Insubria, Varese, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.226

  331

  PDF: 0

• PO22 | Early detection and management of PICC-related thrombosis in oncohematologic patients through serial ultrasound monitoring: a prospective observational study S. Laurenti, M. Schneeberger, G. Rosati, A. Pozzi, M. Padrini, R. Vacchelli, A. Morotti | University of Turin, AUO San Luigi Gonzaga, Orbassano (TO), Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.282

  318

  PDF: 0

• CS03 | Khorana risk score and genomic profiling for prediction of venous thromboembolism in ovarian cancer P. Santini, F. Mancinetti, S.M.P. D’Ambrosio, M. Bigossi, A. D’Errico, E. Fondi, G. Fracassa, E. Ianuà, L. Mastrantoni, G. Anderson, F. Camarda, I. Marino, J. Preziosi, M. Buttarelli, M. Manfredelli, A. Minucci, F. Persiani, L. Giacò, T. Pasciuto, I. Conti, I. Mozzetta, C. Marchetti, V. Salutari, G. Scambia, C. Nero, R. Pola | Agostino Gemelli University Polyclinic Foundation IRCCS, Roma, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.200

  390

  PDF: 0

• PO41 | Comparison of the haemorrhagic phenotype between female and male patients affected by autosomal inherited bleeding disorders in a single-centre cohort B. Borsellino^1,3, C. Zuccotti², L. Guarnera^3,4, C. Biasoli⁵, P. Pedrazzi⁵, T. Martini¹ | ¹Haemophilia Centre, Immune-Haematology and Transfusion Medicine, University Hospital “Città della Salute e della Scienza”, Turin, Italy; ²Department of Clinical Pathology, Bufalini Hospital, Cesena, Italy; ³Department of Biomedicine and Prevention, PhD in Immunology, Molecular Medicine and Applied Biotechnology, University of Roma Tor Vergata, Roma, Italy; ⁴Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH, USA; ⁵Haemophilia and Transfusion Centre, Bufalini Hospital, Cesena, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.304

  281

  PDF: 0

• PO81 | Direct oral anticoagulants in atypical site vein thrombosis: a single centre experience focused on cancer patients U. Mazzarelli¹, A. Guida¹, L. Agrelli¹, M. Amato¹, R. Guarrasi², L. Santaniello², C. Cardamone¹, P. Vitale¹, M. Triggiani¹ | ¹Centro per le Malattie Emorragiche Congenite e Malattie Trombotiche UOC Clinica Immunologica e Reumatologica AOU S. Giovanni di Dio e Ruggi d’Aragona, Salerno; ²UOC Clinica Oncologica AOU S. Giovanni di Dio e Ruggi d’Aragona, Salerno, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.350

  367

  PDF: 0

• PO39 | Bleeding events in Von Willebrand disease type 1 yearly treatable with desmopressin A. Gringeri^1,2, P.M. Mannucci³, M. Gringeri⁴, G. Castaman⁵, F. Peyvandi^3,6 | ¹Fondazione Charta, Milan; ²Centro di Sanità Solidale, Lucca; ³Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center and Fondazione Luigi Villa, Milan; ⁴Department of Medical Biotechnologies and Translational Medicine, Postgraduate School of Clinical Pharmacology and Toxicology, University of Milan; ⁵Centre for Bleeding Disorders and Coagulation, Careggi University Hospital, Firenze; ⁶Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.302

  318

  PDF: 0

• CO07 | Real word management of anticoagulant therapy in brain metastasis: moving toward a multidisciplinary approach in complex cases E. Lotti¹, C. Manneschi², S. Fancelli², F. Scolari¹, F. Crudele¹, D. Poli¹, M. Berteotti¹, D. Rossini³, S. Pillozzi², L. Antonuzzo^2,3, R. Marcucci^1,3 | ¹Disease Unit, Careggi University Hospital, Firenze; ²Oncology Unit, Careggi University Hospital, Firenze; ³Department of Experimental and Clinical Biomedical Sciences, University of Firenze, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.211

  358

  PDF: 0

• PO76 | Thrombosis associated with midline in autoimmune patient: a case report on the use of apixaban in a real-world setting M.V. Cherchi, M. Anedda, S. Che, M. Vacca, M. Caboni, M. Mantega | Department of Internal Medicine, ASL Sulcis, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.345

  324

  PDF: 0

• CO39 | Artificial intelligence in hemophilia management: challenging the need for experts G. Sottilotta¹, D. Megalizzi¹, F. Luise² | ¹UOSD Microcitemie - Emostasi e Trombosi. Grande Ospedale Metropolitano Bianchi-Melacrino-Morelli, Reggio Calabria; ²Laboratorio Analisi, Grande Ospedale Metropolitano Bianchi-Melacrino-Morelli, Reggio Calabria, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.246

  289

  PDF: 0

• CO04 | Direct oral anticoagulants in antiphospholipid syndrome: a single center real-life experience A. Hoxha¹, E. Campello¹, F. Ahmad², L. Spiezia¹, P. Scarinzi¹, G. Gobbo¹, S. Gavasso¹, F. Sartorello¹, C. Simion¹, E. Zanon¹, P. Simioni¹ | ¹Internal Medicine Unit, Thrombotic and Haemorrhagic Centre, Department of Medicine - DIMED; ²Department of Statistical Sciences) University of Padova, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.209

  383

  PDF: 0