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CO081 | RESTORATION OF CEREBRAL MICROVASCULAR STRUCTURE AND FUNCTION IN HEMOPHILIA A MICE THROUGH FVIII GENE THERAPY G. Venturin1, E. Spicuglia1, S. Assanelli1, C. Borsotti1, A. Cucci1, N. Keivan1, E. Borroni1, C. Sgromo1, C. Olgasi2, A. Follenzi1|3 | 1Department of Health Science, Università del Piemonte Orientale, Novara, 28100, Italy; 2Department of Translational Medicine, Università del Piemonte Orientale, Novara, 28100, Italy; 3Department of Attività Integrate Ricerca Innovazione, Azienda Ospedaliero-Universitaria SS. Antonio e Biagio e C. Arrigo, Alessandria, Italy
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CO084 | NEW INSIGHTS INTO HEMOPHILIA A: FACTOR VIII–INTEGRIN Β1 PATHWAY AS KEY REGULATOR OF ENDOTHELIAL CELL FUNCTION A. Cucci1, C. Olgasi2, G. Venturin1, S. Assanelli1, C. Sgromo1, S. Reano2, M. Manfredi2, A. Follenzi1|3 | 1Dip. di Scienze della Salute, Università del Piemonte Orientale, Novara, Italy; 2Dip. di Medicina Traslazionale, Università del Piemonte Orientale, Novara, Italy; 3Dip. Attività Integrate Ricerca Innovazione, AOU SS. Antonio e Biagio e C. Arrigo, Alessandria, Italy
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CO106 | ENDOTHELIAL DYSFUNCTION AS A POSSIBLE ADDITIONAL DRIVER OF BLEEDING IN HERMANSKY–PUDLAK SYNDROME F. Tondi1, G. Purgatorio1, E. Giglio1, E. Petito1, E. Falcinelli1, G. Guglielmini1, P. Gresele1, C. Olgasi2, L. Bury1 | 1Dep. of Medicine and Surgery, Section of Internal and Cardiovascular Medicine, University of Perugia, Perugia, Italy; 2Dep. of Translational Medicine, School of Medicine, University of Piemonte Orientale, Novara, Italy
8PDF: 2
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