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• PO088 | INVESTIGATING THE MEAN PLATELET VOLUME OF PATIENTS WITH LIVER CIRRHOSIS AND CHRONIC LIVER DISEASE: A CASE-CONTROL STUDY B. Clerici^1|2, C. Pisetta¹, C. Urtis^1|2, C. Brizio¹, G. Vismara³, S. Vavassori⁴, A.L. Crosignani⁴, M. Scavone², S. Birocchi¹, S. De Matteis^2|5, P.M. Battezzati^2|4, M.N. Cattaneo⁶, G.M. Podda^1|2 | ¹S.C. Medicina Generale SP, Ospedale San Paolo, ASST Santi Paolo e Carlo, Milano, Italy; ²Dipartimento di Scienze della Salute (DISS), Università degli Studi di Milano, Milano, Italy; ³Servizio di Immunoematologia e Medicina Trasfusionale (SIMT), Ospedale San Paolo, ASST Santi Paolo e Carlo, Milano, Italy; ⁴S.C. Medicina ad indirizzo Epatologico e Gastroenterologia, Ospedale San Paolo, ASST Santi Paolo e Carlo, Università degli Studi di Milano, Milano, Italy; ⁵S.S. Medicina del Lavoro, Ospedale San Paolo, ASST Santi Paolo e Carlo, Università degli Studi di Milano, Milano, Italy; ⁶Fondazione Arianna Anticoagulazione, Bologna, Italy. B. Clerici contributed equally as co-first authors

  Bianca Clerici

  26-10-2026

  https://doi.org/10.4081/btvb.2026.904

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• CO075 | PLATELET ACTIVATION PROFILE IN RELAPSING-REMITTING MULTIPLE SCLEROSIS AND ITS RELATIONSHIP WITH NEURONAL AND ASTROGLIAL BIOMARKERS A. Fioretti¹, M. Scavone¹, A. Mingione^2|3, C. Monzani^2|3, M. Miozzo⁴, F. Martinelli-Boneschi^2|3|5, G.M. Podda¹ | ¹Division of Medicina Generale SP, ASST Santi Paolo e Carlo, Laboratory of Haemostasis and Thrombosis, Dipartimento di Scienze della Salute, Università degli Studi di Milano, Milano, Italy; ²Laboratory of Precision Medicine of Neurological Diseases, Department of Health Science, University of Milano, Milano, Italy; ³CRC “Aldo Ravelli” for Experimental Brain Therapeutics, Department of Health Science, University of Milano, Milano, Italy; ⁴Department of Health Sciences, Division of Medical Genetics, University of Milano, ASST Santi Paolo e Carlo, Milano, Italy; ⁵Clinical Neurology Unit, ASST Santi Paolo e Carlo and Department of Health Sciences, University of Milano, Milano, Italy

  Antonella Fioretti

  26-10-2026

  https://doi.org/10.4081/btvb.2026.777

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• PO036 | EVALUATION OF BREAST MILK AS A POTENTIAL MEDIATOR FOR THE TRANSFER OF MATERNAL ANTI-PLATELET ALLOANTIBODIES IN FETAL AND NEONATAL ALLOIMMUNE THROMBOCYTOPENIA D. Dragonetti¹, C. Autilio¹, S. Pesce², A. Amendola³, A.M. Calabrese¹, V. Martinelli¹, P. Dolce¹, M.C. Cardillo¹, I. Potenza¹, C. Roselli¹, M. Pizzuti³, V. Pafundi¹ | ¹CEDIA Analysis Laboratory, San Carlo Regional Hospital, Potenza, Italy; ²Neonatology Unit, Maternal and Child Health Department, San Carlo Regional Hospital, Potenza, Italy; ³Hematology Unit, San Carlo Regional Hospital, Potenza, Italy

  Daniela Dragonetti

  26-10-2026

  https://doi.org/10.4081/btvb.2026.852

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• CO020 | LEFT ATRIAL ENLARGEMENT AS A MARKER OF ADVERSE CLINICAL OUTCOMES: PRELIMINARY RESULTS OF A PROSPECTIVE COHORT STUDY B. Clerici¹, M. Perego¹, G. Casazza², A.G. Russo³, L. Massironi⁴, A. Moreo⁵, V. Dadone⁶, S. Birocchi¹, F. Bursi⁴, A. Bonelli⁵, P.V. Mattiello¹, F.M. Casanova¹, C. Pisetta¹, M. Scavone¹, M. Guazzi⁴, C. Giannattasio⁵, S. Pierini⁶, G. Agnelli⁷, G.M. Podda¹ | ¹SC Medicina Generale SP, Ospedale San Paolo, ASST Santi Paolo e Carlo, Università degli Studi di Milano, Italy; ²IRCCS Fondazione Ca’ Granda, Policlinico di Milano, Italy; ³SC Unità di Epidemiologia, ATS della Città Metropolitana di Milano, Italy; ⁴SC Cardiologia, Ospedale San Paolo, ASST Santi Paolo e Carlo, Università degli Studi di Milano, Italy; ⁵SC Cardiologia 4, Ospedale Niguarda, ASST Grande Ospedale Metropolitano Niguarda, Milano, Italy; ⁶SC Cardiologia e Unità di Cura Cardiologica (UCC), Ospedale Bassini, ASST Nord Milano, Italy; ⁷SC di Medicina Interna Vascolare e d’Urgenza – Stroke Unit, Università di Perugia, Italy. B. Clerici and M. Perego contributed as co-first authors

  Bianca Clerici

  26-10-2026

  https://doi.org/10.4081/btvb.2026.722

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• CO001 | DERIVATION AND VALIDATION OF THE BLEEPE SCORE FOR RISK STRATIFICATION OF MAJOR BLEEDING IN PATIENTS WITH ACUTE PULMONARY EMBOLISM M. Vedovati¹, L. Cimini¹, V. Valeriano², I. Montenovo¹, A. Murgia³, L. Pierpaoli⁴, G. Tratar⁵, S. Zaccaroni⁶, A. Bongarzoni⁷, A. Vinci¹, A. Mavri⁵, L. Martinelli⁸, G. Pepe⁹, S. Cozzio¹⁰, C. Becattini¹ | ¹University of Perugia, Perugia, Italy; ²Sandro Pertini Hospital, Roma, Italy; ³SS. Annunziata Hospital, Sassari, Italy; ⁴S. Maria delle Croci Hospital, Ravenna, Italy; ⁵University Medical Centre Ljubljana, Ljubljana, Slovenia; ⁶Maggiore Hospital, Bologna, Italy; ⁷ASST Santi Paolo e Carlo-PO San Carlo, Milano, Italy; ⁸Città di Castello Hospital, Città di Castello, Italy; ⁹Versilia Hospital, Tuscany North West Health System, Lido di Camaiore (LU), Italy; ¹⁰Rovereto Hospital, Rovereto, Italy

  Maria Cristina Vedovati

  26-10-2026

  https://doi.org/10.4081/btvb.2026.703

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• PO093 | HOW LONG IS TOO LONG? A CASE OF SEVERE PERSISTENT THROMBOCYTOPENIA B. Clerici^1|2, C. Ghali², M. Scavone², A. Fioretti², M. Perego¹, C. Mondini^1|2, E. Fiorini¹, L. Catarini¹, C. Pescia³, S. Caberlon¹, U. Gianelli^2|3, G.M. Podda^1|2 | ¹S.C. Medicina Generale SP, Ospedale San Paolo, ASST Santi Paolo e Carlo, Milano, Italy; ²Dipartimento di Scienze della Salute (DISS), Università degli Studi di Milano, Milano, Italy; ³S.C. Anatomia Patologica, Ospedale San Paolo, ASST Santi Paolo e Carlo, Milano, Italy

  Bianca Clerici

  26-10-2026

  https://doi.org/10.4081/btvb.2026.909

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• PO142 | CROSS-TALK BETWEEN HEART AND BRAIN IN ATRIAL FIBRILLATION: ASSOCIATIONS BETWEEN CARDIAC REMODELING AND CEREBROVASCULAR LESION BURDEN IN THE STRAT-AF STUDY F. Alfano^1|2, C. Barbato³, M. Berteotti^1|2, L. Cosco^1|2, A. Sammartino^1|2, G. Guidotti^1|2, V. Liberati^1|2, G. Iula^1|2, M. Papi^1|2, A. Fidanzati^1|2, B. Formelli³, E. Barucci³, G. Salti³, F. Fratini³, T. Lo Castro³, C. Parenti⁴, E. Fainardi^2|5, A. Di Carlo⁴, E. Salvadori¹, A. Poggesi^1|3, R. Marcucci^1|2 | ¹Department of Experimental and Clinical Medicine, University of Florence, Firenze, Italy; ²Center for Atherothrombotic Diseases, Careggi University Hospital, Firenze, Italy; ³NEUROFARBA Department, Neuroscience Section, University of Florence, Firenze, Italy; ⁴Institute of Neuroscience, Italian National Research Council, Sesto Fiorentino, Italy; ⁵Neuroradiology Unit, Careggi University Hospital, Firenze, Italy

  Francesco Alfano

  26-10-2026

  https://doi.org/10.4081/btvb.2026.958

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• CO091 | DOWNREGULATION OF MARKERS OF PLATELET ACTIVATION, PLATELET TURNOVER, AND PLATELET DESIALYLATION IN GOOD RESPONDERS TO FIRST-LINE TREATMENT(S) FOR IMMUNE THROMBOCYTOPENIA B. Clerici^1|2, C. Ghali², M. Scavone², A. Fioretti², E.G. Bossi², S. Birocchi¹, E. Tarasconi^1|2, G. D'Avanzo¹, M. Carpenedo³, S. Caberlon², G.M. Podda^1|2 | ¹.S.C. Medicina Generale SP, Ospedale San Paolo, ASST Santi Paolo e Carlo, Milano, Italy; ²Dipartimento di Scienze della Salute (DISS), Università degli Studi di Milano, Italy; ³S.S. Ematologia Non Oncologica, ASST Grande Ospedale Metropolitano Niguarda, Milano, Italy. B. Clerici and C. Ghali contributed as co-first authors

  Bianca Clerici

  26-10-2026

  https://doi.org/10.4081/btvb.2026.793

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• PO122 | SUCCESSFUL MANAGEMENT OF THERAPEUTIC ANTICOAGULATION FOR PROVOKED VENOUS THROMBOEMBOLISM IN A PATIENT WITH FACTOR VII DEFICIENCY AND SEPTIC SHOCK S. Birocchi¹, F.M. Monda¹, B. Clerici^1|2, M. Scavone², R. Cabiddu¹, E. Pontisso¹, C. Ortelli¹, M.L.G. Perego¹, E. Fiorini¹, L. Catarini¹, A. Bortoli¹, M. Manzoni¹, F.M. Casanova¹, A. Tripodi^2|3, F. Peyvandi^2|3, G.M. Podda^1|2 | ¹S.C. Medicina Generale 2, Ospedale San Paolo, ASST Santi Paolo e Carlo, Milano, Italy; ²Dipartimento di Scienze della Salute, Università degli Studi di Milano, Italy; ³Centro di riferimento emofilia e trombosi "Emilio Bianchi"; ⁴S. Birocchi and F.M. Monda contributed equally as co-first authors

  Simone Birocchi

  26-10-2026

  https://doi.org/10.4081/btvb.2026.938

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• PO105 | IMPACT OF ECOG PERFORMANCE STATUS ON CANCER-ASSOCIATED THROMBOSIS TREATED WITH DOACS: DATA FROM A MULTICENTER COHORT STUDY R. Talerico¹, F. Mancinetti¹, C. Sacco², M. Mazzetti³, E. Campello⁴, S. Birocchi⁵, S. Beccatini⁶, A. Porfidia¹, C. Lodigiani², P. Simioni⁴, G.M. Podda⁵, I. Mastandrea², C. Becattini⁶, R. Pola¹, M.C. Vedovati⁶ | ¹Thrombosis Unit, Department of Geriatric, Orthopedic, and Rheumatologic Sciences, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy; ²Thrombosis and Hemorrhagic Diseases Unit, IRCCS Humanitas Research Hospital, Rozzano, Milano, Italy; ³Interdisciplinary Internal Medicine, Careggi University Hospital, Firenze, Italy; ⁴First Chair of Internal Medicine and Thrombotic and Hemorrhagic Diseases Unit, Department of Medicine, University of Padova, Italy; ⁵Medicine II Unit, ASST Santi Paolo e Carlo, Department of Health Sciences, University of Milano, Milano, Italy; ⁶Internal, Vascular and Emergency Medicine– Stroke Unit, University of Perugia, Perugia, Italy

  Rosa Talerico

  26-10-2026

  https://doi.org/10.4081/btvb.2026.921

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• CO068 | FACTORS AFFECTING SPONTANEOUS PLATELET AGGREGATION IN HEALTHY SUBJECTS AND PATIENTS WITH STABLE CORONARY ARTERY DISEASE M. Scavone¹, A. Fioretti¹, C. Ghali¹, B. Clerici¹, E. Popov², G.M. Podda¹, M. Cattaneo³ | ¹Laboratorio di emostasi e trombosi, Dipartimento di Scienze della Salute, Università degli Studi di Milano, Divisione di Medicina Generale II, ASST Santi Paolo e Carlo, Italy; ²National Medical Research Center of Cardiology, Ministry of Health of the Russian Federation, Moscow, Russia; ³Fondazione Arianna Anticoagulazione, Bologna, Italy

  Mariangela Scavone

  26-10-2026

  https://doi.org/10.4081/btvb.2026.770

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• CO061 | IMMUNOFLUORESCENCE MICROSCOPY REVEALS PLATELET- AND RED BLOOD CELL ALTERATIONS AS MORPHOLOGICAL BIOMARKERS IN MYELOPROLIFERATIVE NEOPLASMS C. Zaninetti¹, L. Kaderali², L. Vater¹, S. Semenowitsch¹, L. Porges¹, T.M. Schnöder^3|4, C.C. Crodel⁵, J. Fuhrmann¹, J. Wesche¹, C. Freyer¹, T. Thiele¹, F.H. Heidel^3|6, A. Greinacher¹ | ¹Institut für Transfusionsmedizin Universitätsmedizin Greifswald, Greifswald, Germany; ²Institut für Bioinformatik, Universitätsmedizin Greifswald, Greifswald, Germany; ³Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany; ⁴Innere Medizin C, Universitätsmedizin Greifswald, Greifswald, Germany; ⁵Innere Medizin II, Abt. Hämatologie und Onkologie, Universitätsklinikum Jena, Jena, Germany; ⁶Leibniz Institute on Aging, Fritz-Lipmann Institute, Jena, Germany

  Carlo Zaninetti

  26-10-2026

  https://doi.org/10.4081/btvb.2026.763

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• CO057 | THROMBOPOIETIN-PLATELET AXIS IN METABOLIC-ASSOCIATED STEATOTIC LIVER DISEASE M. Alfonsetti¹, P. Simeone¹, R. Liani¹, M. Frezza¹, B. Di Marco¹, A. Cipollone¹, C. Della Penna¹, L. Cantagallo¹, G. Ciferni¹, L. Del Rosso¹, M. Caporale¹, S. Brandolino², E. Vitacolonna², P. Di Carlo³, F. Cipollone¹, F. Santilli¹ | ¹Department of Medicine and Aging Sciences, Center for Advanced Studies and Technology (CAST), University of Chieti, Chieti, Italy, University General Medicine Division, Medical Department, SS. Annunziata Hospital, Chieti, Italy; ²Department of Medicine and Aging, School of Medicine and Health Sciences, G. d'Annunzio University, Chieti, Italy; ³Department of Innovative Technologies in Medicine & Dentistry, "G. d'Annunzio" University of Chieti-Pescara, Chieti, Italy

  Paola Giustina Maria Simeone

  26-10-2026

  https://doi.org/10.4081/btvb.2026.759

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• CO056 | URINARY MARKERS OF PLATELET ACTIVATION AND OXIDATIVE STRESS IN ATHEROSCLEROTIC CARDIOVASCULAR DISEASE IN TYPE 2 DIABETES M. Alfonsetti¹, P. Simeone¹, R. Liani¹, M. Frezza¹, B. Di Marco¹, A. Cipollone¹, D. D’ Ardes¹, T. Taverriti¹, C. Della Penna¹, L. Cantagallo¹, G. Ciferni¹, L. Del Rosso¹, M. Caporale¹, S. Brandolino², E. Vitacolonna², P. Di Carlo³, F. Cipollone¹, F. Santilli¹ | ¹Department of Medicine and Aging Sciences, Center for Advanced Studies and Technology (CAST), University of Chieti, Chieti, Italy, University General Medicine Division, Medical Department, SS. Annunziata Hospital, Chieti, Italy; ²Department of Medicine and Aging, School of Medicine and Health Sciences, G. d'Annunzio University, Chieti, Italy; ³Department of Innovative Technologies in Medicine & Dentistry, "G. d'Annunzio" University of Chieti-Pescara, Chieti, Italy

  Paola Giustina Maria Simeone

  26-10-2026

  https://doi.org/10.4081/btvb.2026.758

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• PO033 | PLATELET COUNT AND PERIPROCEDURAL MAJOR BLEEDING IN CIRRHOTIC PATIENTS UNDERGOING INVASIVE PROCEDURES: INDIVIDUAL PATIENT DATA META-ANALYSIS E. Tarasconi^1|2, E. Pontisso¹, M. Manzoni¹, S. Birocchi¹, B. Clerici¹, E.G. Giannini³, A. Iacobellis⁴, Shalimar⁵, P. Ponzo⁶, F. Giuliante⁷, A. Lauterio⁸, L. Massicotte⁹, N. Cocero¹⁰, V. Ronca¹¹, G.M. Podda^1|2 | ¹S.C. Medicina Generale II, Ospedale San Paolo Polo Universitario, ASST Santi Paolo e Carlo, Università degli Studi di Milano, Italy; ²Dipartimento di Scienze della Salute (DISS), Università degli Studi di Milano, Italy; ³Gastroenterology Unit, Department of Internal Medicine, University of Genoa, Italy; ⁴Department of Gastroenterology and Endoscopy, Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy; ⁵Department of Gastroenterology and Human Nutrition Unit, All India Institute of Medical Sciences, New Delhi, India; ⁶Division of Gastroenterology and Hepatology, Città della Salute e della Scienza Hospital, University of Torino, Italy; ⁷Hepatobiliary Surgery Unit, Foundation and Teaching Hospital Sacred Heart IRCCS A. Gemelli, Catholic University of the Sacred Heart, Roma, Italy; ⁸General Surgery and Abdominal Organ Transplantation, ASST Grande Ospedale Metropolitano Milano Niguarda School of Medicine and Surgery, University of Milan-Bicocca, Milano, Italy; ⁹Department of Anesthesiology, Centre Hôspitalier de l’Université de Montréal- Hôpital Saint-Luc, Montreal, Canada; ¹⁰Senior Consultant, Oral Surgery Section of the Dental School of the University of Torino at the Azienda Ospedaliera Città della Salute e della Scienza of Torino, Italy; ¹¹IRCCS Humanitas Research Hospital, Department of Gastroenterology, Division of Internal Medicine and Hepatology, Milano, Italy. E. Tarasconi and E. Pontisso contributed as co-first authors

  Elisa Tarasconi

  26-10-2026

  https://doi.org/10.4081/btvb.2026.849

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