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  PO08 | NEXT-GENERATION THROMBOLYTICS: ENGINEERING STREPTOKINASE FOR ENHANCED ACTIVITY AND REDUCED IMMUNOGENICITY M. Kanwal^1|2 | ¹Consiglio Nazionale delle Ricerche, Naples, Italy; ²Department of Environmental, Biological and Chemical Sciences and Technologies, University of Campania "Luigi Vanvitelli", Italy

  ICTHIC 2026

  16-04-2026

  https://doi.org/10.4081/btvb.2026.504

  478

  PDF: 81

• CO31 | Immune system profiling in FVIII-treated and emicizumab-treated pediatric HA patients A. Cottonaro¹, S. Akula¹, B. Pollio², I. Ricca², T. Martini², J. Agnelli Giacchello³, P. Sciancalepore³, R. Santi³, A. Follenzi^1,3, S. Merlin¹ | ¹Università del Piemonte Orientale, Health Sciences, Novara; ²A.O. Città della Salute e della Scienza, SIMT Immunohematology and Transfusion Medicine Service, Diagnostic Department, Torino; ³Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo, Alessandria, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.238

  635

  PDF: 15
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  Growing weapons to fight hemophilia

  Pier Mannuccio Mannucci

  23-02-2023

  https://doi.org/10.4081/btvb.2023.64

  1479

  PDF: 575
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  PO44 | PREDICTORS OF ONE-YEAR MORTALITY IN NEWLY DIAGNOSED METASTATIC BREAST CANCER: THE PROGNOSTIC ROLE OF HEMOSTATIC BIOMARKERS AND EARLY THROMBOEMBOLISM M. Marchetti^1|2|3, P. Gomez-Rosas^1|4|5, S. Bolognini¹, C. Ticozzi¹, D. Romeo¹, F. Schieppati^1|3, L. Barcella^1|3, F. Petrelli⁶, A. D'Alessio⁷, R. Labianca⁷, A. Falanga^1|2|3 | ¹Immunohematology and Transfusion Medicine, Hospital Papa Giovanni XXIII, Bergamo, Italy; ²School of Medicine and Surgery, University of Milan Bicocca, Milan, Italy; ³ERN EuroBloodNet; ⁴Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, The Netherlands; ⁵Hospital de Oncologia, Unidad Medica de Alta Especialidad (UMAE), Centro Medico Nacional Siglo XXI, Instituto Mexicano del Seguro Social (IMSS), Mexico City, Mexico; ⁶Oncology Unit, Hospital Treviglio-Caravaggio, Treviglio, Italy; ⁷Fondazione ARTET Onlus, Bergamo, Italy; *On behalf of the Hypercan Investigators

  ICTHIC 2026

  16-04-2026

  https://doi.org/10.4081/btvb.2026.538

  445

  PDF: 105
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  The therapeutic landscape of cancer-associated splanchnic vein thrombosis

  Alessia Abenante, Filippo Catalani, Walter Ageno

  16-04-2026

  https://doi.org/10.4081/btvb.2026.458

  304

  PDF: 148

• PO33 | Whole blood hypercoagulable profiles in patients with rheumatoid arthritis L. Spiezia¹, A. Giollo², C. Samà¹, A. Benetti¹, L. Di Luozzo², M. Salvato², A. Doria², P. Simioni¹ | ¹First Chair of Internal Medicine, Thrombotic and Hemorrhagic Diseases Unit, Department of Medicine, University Hospital of Padova; ²Rheumatology Unit, Department of Medicine, University Hospital of Padova, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.296

  621

  PDF: 16

• CO03 | Early discharge and home treatment of low-risk pulmonary embolism: a cohort study E. Ruggeri¹, L. Vulcano¹, W. Ageno², F. Cortellaro³, M.P. Donadini^3,4 | ¹Scuola di Medicina, Università degli Studi dell’Insubria, Varese; ²Dipartimento di Medicina, Università degli Studi di Padova; ³Pronto Soccorso e Medicina d’Urgenza, Ospedale di Circolo, ASST Sette Laghi, Varese; ⁴Dipartimento di Medicina e Chirurgia, Università degli Studi dell’Insubria, Varese, Italy

  22-10-2025

  https://doi.org/10.4081/btvb.2025.208

  661

  PDF: 23