Thrombophilia work-up and clinical outcomes in Indian patients with unprovoked venous and arterial thrombosis aged 18-50 years

Harimadhavan, Monisha; Ram, Bharath; G, Karthick R; Shetty, Devi Prasad; Prabhu, Shilpa; S, Nataraj K; Nayak, Akshatha; Damodar, Sharat; Zanon, Ezio; Castaman, Giancarlo; Federici, Augusto Bramante; Mancuso, Maria Elisa; Pasut, Gianfranco; Tosetto, Alberto; Rocino, Angiola; Santoro, Rita Carlotta; Barcellona, Doris; Tripodi, Armando; Di Castelnuovo, Augusto; Persichillo, Mariarosaria; Candura, Fabio; Marchesini, Emanuela; Forni, Gian Luca; Gringeri, Alessandro; Gentilini, Ilaria; Tricoli, Mirko; Najjar, Osama; Teofili, Luciana

doi:10.4081/btvb..193

Original Articles

All Items

A nitric oxide-donor pravastatin hybrid drug exerts antiplatelet and antiatherogenic activity in mice

Stefania Momi, Giuseppe Guglielmini, Giulia Ciarroca Taranta, Elisa Giglio, Angela Monopoli, Paolo Gresele

https://doi.org/10.4081/btvb.2022.19

5023

PDF: 376

Ankle brachial index for the diagnosis of asymptomatic lower extremity peripheral arterial disease

Francesco Cicconi

https://doi.org/10.4081/btvb.2024.128

2180

PDF: 501

Association between non-O blood type and early unexplained recurrent spontaneous abortion in women with and without inherited thrombophilia

Anna Poretto, Elisabetta Borella, Giacomo Turatti, Michelangelo Marobin, Elena Campello, Daniela Tormene, Paolo Simioni, Luca Spiezia

https://doi.org/10.4081/btvb.2022.47

1564

PDF: 318

Attitude to clinical research among health professionals affiliated with the Italian Federation of Centers for the Diagnosis of Thrombotic Disorders and the Surveillance of the Antithrombotic Therapies (FCSA)

Daniela Poli, Riccardo Tartaglia, Doris Barcellona , Paolo Bucciarelli , Antonio Ciampa, Elvira Grandone, Giuseppe Malcangi, Giuseppe Rescigno, Vincenzo Toschi, Sophie Testa, Alessandro Squizzato

https://doi.org/10.4081/btvb.2023.59

961

PDF: 308

Circulating albumin-to-fibrinogen ratio may be a risk indicator for venous thromboembolism: findings from a population-based prospective cohort study

Setor K. Kunutsor, Sudhir Kurl, Ari Voutilainen, Jari Laukkanen

https://doi.org/10.4081/btvb.2022.36

1424

PDF: 306

Clinical and radiological characteristics of cerebral vein thrombosis: a retrospective study

Mosaad Almegren

https://doi.org/10.4081/btvb.2023.85

909

PDF: 248

Combined oral contraceptives and the risk of venous thromboembolism carriers of antithrombin, protein C or S deficiency: Sub-analysis of a prospective cohort study

Daniela Tormene, Elena Campello, Chiara Simion, Anna Poretto, Paolo Prandoni, Paolo Simioni

https://doi.org/10.4081/btvb.2022.42

1283

PDF: 378

Comparison among three different bleeding scores and the thrombin generation assay to assess the different hemorrhagic phenotypes in patients with FVII deficiency

Samantha Pasca, Cristina Santoro, Chiara Ambaglio, Marisanta Napolitano, Marta Milan, Letizia Natali, Silvia Nannizzi, Filippo Mori, Paolo Simioni, Ezio Zanon

https://doi.org/10.4081/btvb.2022.12

5361

PDF: 403

Crosstalk between hemostasis inhibitors and cholesterol biomarkers in multiple sclerosis

Robert Parambi, Nicole Ziliotto, Francesco Bernardi , Marcello Baroni , Richard W Browne , Dejan Jakimovski, Bianca Weinstock-Guttman, Robert Zivadinov, Murali Ramanathan

https://doi.org/10.4081/btvb.2022.41

2568

PDF: 371

Supplementary Files: 103

Descriptive analysis of patients positive for anti-phospholipid antibodies included in two Italian registries

Vittorio Pengo, Luca Sarti, Emilia Antonucci, Stefania Di Agostino, Elisa Bison, Gentian Denas, Daniela Poli, Pier Luigi Meroni, Roberto Gerli, Antonella Radice, Gualtiero Palareti, on behalf of FIRMA group and START collaborators

https://doi.org/10.4081/btvb.2023.92

1156

PDF: 355

Diagnostic and management practices for inherited fibrinogen disorders: a nationwide survey of Italian Hemophilia Treatment Centers

Renato Marino, Silvia Linari, Marzia Leotta, Antonio Coppola, Chiara Biasoli, Maria Elisa Mancuso, Flora Peyvandi, Cristina Santoro, Ezio Zanon, Rita Carlotta Santoro

https://doi.org/10.4081/btvb.2025.372

408

PDF: 57

HTML: 36

Supplementary: 18

Appendix: 29

Diagnostic challenges in current laboratory practice at Italian Hemophilia Centers: findings from a nationwide survey

Tiziano Martini, Alessandra Valpreda, Marina Marchetti, Alberto Catalano, Laura Contino, Raimondo De Cristofaro, Augusto Bramante Federici, Ilaria Quaglia, Rossana Rossi, Rita Carlotta Santoro, Armando Tripodi, Angelo Claudio Molinari

https://doi.org/10.4081/btvb.2026.431

55

PDF: 13

Supplementary: 2

Evaluation of Coaguchek^®Pro II coagulation testing device performance to assess direct oral anticoagulant action. The DOAC-CHECK study

Cristina Legnani, Michela Cini, Sophie Testa, Alberto Tosetto, Claudia Dellanoce, Stefania Bellesso, Giuseppe Carli, Ilaria Nichele, Laura Lissandrini, Serena Zorzi, Emilia Antonucci, Gualtiero Palareti

https://doi.org/10.4081/btvb.2022.37

1946

PDF: 390

Influence of emicizumab on protein C-mediated clotting regulation

Federica Mancazzo, Antonia Vitulli, Lavinia Dirienzo, Concetta T. Ammollo, Fabrizio Semeraro, Mario Colucci

https://doi.org/10.4081/btvb.2023.89

2376

PDF: 338

Supplementary Material: 81

Major bleedings in mechanical prosthetic heart valves patients on Vitamin K antagonist treatment. Data from the PLECTRUM Study

Daniela Poli, Emilia Antonucci, Gualtiero Palareti, Roberto Facchinetti, Pietro Falco, Giuseppina Serricchio, Teresa Lerede, Lucilla Masciocco, Paolo Gresele, Sophie Testa

https://doi.org/10.4081/btvb.2022.34

5254

PDF: 483

Supplementary Files: 181

Management of anticoagulation in atrial fibrillation patients in Italy: insight from the Atrial Fibrillation-Survey on Anticoagulated Patients Register (AF-START)

Daniela Poli, Walter Ageno, Emilia Antonucci, Salvatore Bradamante, Eugenio Bucherini, Paolo Chiarugi, Antonio Chistolini, Benilde Cosmi, Anna Falanga, Antonio Insana, Domenico Lione, Rosa Maria Lombardi, Giuseppe Malcangi, Rossella Marcucci, Giuliana Martini, Lucilla Masciocco, Carmelo Paparo, Daniele Pastori, Simona Pedrini, Vittorio Pengo, Pasquale Pignatelli, Andrea Toma, Sophie Testa, Gualtiero Palareti

https://doi.org/10.4081/btvb.2023.84

1763

PDF: 467

Supplementary File: 217

Pathways for lower extremity superficial vein thrombosis management in an academic medical center

Gisoo Imani, Aaron Wilson, Sara Vazquez, Daniel M. Witt

https://doi.org/10.4081/btvb.2025.155

607

PDF: 165

Persistence of functional anti-PF4 antibodies and neutrophil activation in vaccine-induced immune thrombotic thrombocytopenia

Eleonora Petito, Anna Maria Mezzasoma, Emanuela Falcinelli, Chiara Conti, Erica De Candia, Raimondo De Cristofaro, Silvia Sorrentino, Gian Marco Podda, Mariangela Scavone, Anna Falanga, Marina Marchetti, Luca Barcella, Stefania Basili, Lucia Stefanini, Andrea Boccatonda, Laura Contino, Patrizia Sciancalepore, Igor Florio, Egidio Imbalzano, Rossella Marcucci, Angela Rogolino, Patrizia Noris, Marta Panella, Rita Santoro, Maria Costanza Turi, Gaetano Vaudo, Rosa Curcio, Paolo Gresele

https://doi.org/10.4081/btvb.2025.400

586

PDF: 90

HTML: 59

Plasma fibrinogen levels and all-cause and cause-specific mortality in an Italian adult population: results from the Moli-sani study

Roberta Parisi, Simona Costanzo, Romy de Laat-Kremers, Augusto Di Castelnuovo, Amalia De Curtis, Teresa Panzera, Mariarosaria Persichillo, Chiara Cerletti, Giovanni de Gaetano, Maria Benedetta Donati, Licia Iacoviello, Bas de Laat , for the Moli-sani Study Investigators

https://doi.org/10.4081/btvb.2023.46

2059

PDF: 522

APPENDIX: 170

Platelet distribution width is associated with cardiovascular mortality in an adult general population

Benedetta Izzi, Simona Costanzo, Alessandro Gialluisi, Amalia De Curtis, Sara Magnacca, Teresa Panzera, Augusto Di Castelnuovo, Maria Benedetta Donati, Chiara Cerletti, Marc F. Hoylaerts, Giovanni de Gaetano, Licia Iacoviello, *on behalf of the Moli-sani Study Investigators

https://doi.org/10.4081/btvb.2023.83

2715

PDF: 394

Supplementary Material: 90

Pleiotropic effects of anti-thrombotic therapies: have direct oral anticoagulants any anti-inflammatory effect?

Anna Maria Gori, Eleonora Camilleri, Alessia Bertelli, Angela Rogolino, Francesca Cesari, Elena Lotti, Tommaso Capobianco, Walther Iannotti, Betti Giusti , Rossella Marcucci

https://doi.org/10.4081/btvb.2022.50

1493

PDF: 442

Restrained glycoprotein VI-induced platelet signaling by tyrosine protein phosphatases independent of phospholipase Cγ2

Jingnan Huang, Delia I. Fernández, Jinmi Zou, Xueqing Wang, Johan W.M. Heemskerk, Ángel García

https://doi.org/10.4081/btvb.2023.93

658

PDF: 269

Safety and efficacy of treatment with vitamin K antagonists in patients managed in a network of anticoagulation services or as routine general care

Gianfranco De Girolamo, Luca Sarti, Sonia Cecoli, Karin Bonora, Chiara Ajolfi, Francesco Bellelli, Valeria Coluccio, Gualtiero Palareti, Marco Marietta

https://doi.org/10.4081/btvb.2022.9

961

PDF: 300

Supplementary Files: 113

Still unmet problems with low molecular weight heparin prophylaxis of venous thromboembolism. An Italian survey

Stefania Cavazza, Gualtiero Palareti*

https://doi.org/10.4081/btvb.2025.177

1260

PDF: 207

HTML: 86

Supplementary: 57

The landscape of rare coagulation factor deficiency management in Italy: a national hemophilia center survey

Silvia Linari, Renato Marino, Marzia Leotta, Antonio Coppola, Patrizia Di Gregorio, Augusto Bramante Federici, Flora Peyvandi, Cristina Santoro, Ezio Zanon, Rita Carlotta Santoro

https://doi.org/10.4081/btvb.2025.369

939

PDF: 122

HTML: 36

Appendix: 55

The role of dyslipidemia and gender-related risk factors in the management of patients with abdominal aortic aneurysms: a survey from the Italian Society of Angiology and Vascular Medicine and a call to action

Martina Berteotti, Walter Ageno, Rossella Marcucci, Andrea Stella, Paolo Zamboni, Romeo Martini

https://doi.org/10.4081/btvb.2025.164

1083

PDF: 206

Thrombophilia work-up and clinical outcomes in Indian patients with unprovoked venous and arterial thrombosis aged 18-50 years

Monisha Harimadhavan, Bharath Ram, Karthick R G, Devi Prasad Shetty, Shilpa Prabhu, Nataraj K S, Akshatha Nayak, Sharat Damodar

https://doi.org/10.4081/btvb.2026.193

1338

PDF: 205

Thrombosis and hemostasis at the University of Padua: a reappraisal on the occasion of its 800th year of history

Paolo Simioni, Vittorio Pengo, Paolo Prandoni

https://doi.org/10.4081/btvb.2022.52

2428

PDF: 341

“Living under the sword of Damocles”: a psychological support project for patients with immune thrombocytopenia and their caregivers

Giuseppe Auteri, Laura Ricci, Nicola Vianelli, Barbara Lovrencic

https://doi.org/10.4081/btvb.2025.161

752

PDF: 233

Appendix A: 72

Appendix B: 106

Original Articles

All Items

A nitric oxide-donor pravastatin hybrid drug exerts antiplatelet and antiatherogenic activity in mice

Ankle brachial index for the diagnosis of asymptomatic lower extremity peripheral arterial disease

Association between non-O blood type and early unexplained recurrent spontaneous abortion in women with and without inherited thrombophilia

Attitude to clinical research among health professionals affiliated with the Italian Federation of Centers for the Diagnosis of Thrombotic Disorders and the Surveillance of the Antithrombotic Therapies (FCSA)

Circulating albumin-to-fibrinogen ratio may be a risk indicator for venous thromboembolism: findings from a population-based prospective cohort study

Clinical and radiological characteristics of cerebral vein thrombosis: a retrospective study

Combined oral contraceptives and the risk of venous thromboembolism carriers of antithrombin, protein C or S deficiency: Sub-analysis of a prospective cohort study

Comparison among three different bleeding scores and the thrombin generation assay to assess the different hemorrhagic phenotypes in patients with FVII deficiency

Crosstalk between hemostasis inhibitors and cholesterol biomarkers in multiple sclerosis

Descriptive analysis of patients positive for anti-phospholipid antibodies included in two Italian registries

Diagnostic and management practices for inherited fibrinogen disorders: a nationwide survey of Italian Hemophilia Treatment Centers

Diagnostic challenges in current laboratory practice at Italian Hemophilia Centers: findings from a nationwide survey

Evaluation of Coaguchek^®Pro II coagulation testing device performance to assess direct oral anticoagulant action. The DOAC-CHECK study

Influence of emicizumab on protein C-mediated clotting regulation

Major bleedings in mechanical prosthetic heart valves patients on Vitamin K antagonist treatment. Data from the PLECTRUM Study

Management of anticoagulation in atrial fibrillation patients in Italy: insight from the Atrial Fibrillation-Survey on Anticoagulated Patients Register (AF-START)

Pathways for lower extremity superficial vein thrombosis management in an academic medical center

Persistence of functional anti-PF4 antibodies and neutrophil activation in vaccine-induced immune thrombotic thrombocytopenia

Plasma fibrinogen levels and all-cause and cause-specific mortality in an Italian adult population: results from the Moli-sani study

Platelet distribution width is associated with cardiovascular mortality in an adult general population

Pleiotropic effects of anti-thrombotic therapies: have direct oral anticoagulants any anti-inflammatory effect?

Restrained glycoprotein VI-induced platelet signaling by tyrosine protein phosphatases independent of phospholipase Cγ2

Safety and efficacy of treatment with vitamin K antagonists in patients managed in a network of anticoagulation services or as routine general care

Still unmet problems with low molecular weight heparin prophylaxis of venous thromboembolism. An Italian survey

The landscape of rare coagulation factor deficiency management in Italy: a national hemophilia center survey

The role of dyslipidemia and gender-related risk factors in the management of patients with abdominal aortic aneurysms: a survey from the Italian Society of Angiology and Vascular Medicine and a call to action

Thrombophilia work-up and clinical outcomes in Indian patients with unprovoked venous and arterial thrombosis aged 18-50 years

Thrombosis and hemostasis at the University of Padua: a reappraisal on the occasion of its 800th year of history

“Living under the sword of Damocles”: a psychological support project for patients with immune thrombocytopenia and their caregivers

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